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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for tp53

Z-value: 2.11

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Transcription factors associated with tp53

Gene Symbol Gene ID Gene Info
tp53
ENSDARG00000035559 tumor protein p53
tp53
ENSDARG00000115148 tumor protein p53

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tp53dr11_v1_chr5_+_24087035_240870350.511.2e-07Click!

Activity profile of tp53 motif

Sorted Z-values of tp53 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_31428763 39.63 ENSDART00000053545
zgc:153284
zgc:153284
chr5_+_29831235 29.91 ENSDART00000109660
f11r.1
F11 receptor, tandem duplicate 1
chr6_-_42983843 25.72 ENSDART00000130666
tnfrsf18
tumor necrosis factor receptor superfamily, member 18
chr12_-_5505205 24.40 ENSDART00000092319
abi3b
ABI family, member 3b
chr8_+_32406885 24.28 ENSDART00000167600
epgn
epithelial mitogen homolog (mouse)
chr22_-_6404807 24.03 ENSDART00000149399
ENSDART00000063420
si:rp71-1i20.2
si:rp71-1i20.2
chr12_+_22576404 21.32 ENSDART00000172053
capgb
capping protein (actin filament), gelsolin-like b
chr23_+_23232136 19.52 ENSDART00000126479
ENSDART00000187764
plekhn1
pleckstrin homology domain containing, family N member 1
chr7_-_2430286 18.83 ENSDART00000129312
zgc:66473
zgc:66473
chr16_+_38201840 18.65 ENSDART00000044971
myo1eb
myosin IE, b
chr5_-_37959874 18.65 ENSDART00000031719
mpzl2b
myelin protein zero-like 2b
chr4_+_25630555 18.35 ENSDART00000133425
acot15
acyl-CoA thioesterase 15
chr19_+_2835240 18.04 ENSDART00000190838
CDCP1
CUB domain containing protein 1
chr5_-_57686487 17.97 ENSDART00000074264
crfb12
cytokine receptor family member B12
chr3_-_50147160 17.70 ENSDART00000191341
btr02
bloodthirsty-related gene family, member 2
chr3_+_16229911 17.32 ENSDART00000121728
rpl19
ribosomal protein L19
chr13_+_24755049 17.12 ENSDART00000134102
col17a1b
collagen, type XVII, alpha 1b
chr2_-_37743834 16.49 ENSDART00000088040
ENSDART00000191057
myo9b
myosin IXb
chr10_-_4980150 16.27 ENSDART00000093228
mat2al
methionine adenosyltransferase II, alpha-like
chr25_+_34641536 16.12 ENSDART00000167033
CABZ01079011.1

chr7_-_26049282 15.91 ENSDART00000136389
ENSDART00000101124
rnaseka
ribonuclease, RNase K a
chr5_+_27404946 15.47 ENSDART00000121886
ENSDART00000005025
hdr
hematopoietic death receptor
chr18_+_7150144 15.21 ENSDART00000114690
vwf
von Willebrand factor
chr21_+_25688388 15.21 ENSDART00000125709
bicdl2
bicaudal-D-related protein 2
chr18_+_35861930 14.74 ENSDART00000185223
ppp1r13l
protein phosphatase 1, regulatory subunit 13 like
chr16_-_33806390 14.46 ENSDART00000160671
rspo1
R-spondin 1
chr4_-_70050522 14.32 ENSDART00000100252
si:ch211-171l17.14
si:ch211-171l17.14
chr3_-_28828242 13.91 ENSDART00000151445
si:ch211-76l23.4
si:ch211-76l23.4
chr7_-_2292403 13.63 ENSDART00000075856
zgc:66473
zgc:66473
chr5_+_27898226 13.12 ENSDART00000098604
ENSDART00000180251
adam28
ADAM metallopeptidase domain 28
chr16_+_34111919 12.59 ENSDART00000134037
ENSDART00000006061
ENSDART00000140552
tcea3
transcription elongation factor A (SII), 3
chr3_+_30922947 12.56 ENSDART00000184060
cldni
claudin i
chr3_-_50146854 12.46 ENSDART00000157047
si:dkey-120c6.5
si:dkey-120c6.5
chr6_-_19270484 12.40 ENSDART00000186894
ENSDART00000188709
zgc:174863
zgc:174863
chr17_-_10838434 12.18 ENSDART00000064597
lgals3b
lectin, galactoside binding soluble 3b
chr13_-_25774183 12.18 ENSDART00000046981
pdlim1
PDZ and LIM domain 1 (elfin)
chr10_+_4987766 12.15 ENSDART00000121959
si:ch73-234b20.5
si:ch73-234b20.5
chr22_-_15693085 12.13 ENSDART00000141861
si:ch1073-396h14.1
si:ch1073-396h14.1
chr5_+_24089334 11.51 ENSDART00000183748
tp53
tumor protein p53
chr4_-_71311438 11.22 ENSDART00000168021
si:dkeyp-123a12.2
si:dkeyp-123a12.2
chr11_+_10975481 11.14 ENSDART00000160488
itgb6
integrin, beta 6
chr14_+_36889893 10.96 ENSDART00000124159
si:ch211-132p1.3
si:ch211-132p1.3
chr15_-_29387446 10.87 ENSDART00000145976
ENSDART00000035096
serpinh1b
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr13_+_25422009 10.77 ENSDART00000057686
calhm2
calcium homeostasis modulator 2
chr16_-_30903930 10.77 ENSDART00000143996
dennd3b
DENN/MADD domain containing 3b
chr16_-_40459104 10.70 ENSDART00000032389
plekhf2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr12_-_33789006 10.59 ENSDART00000034550
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr20_-_26929685 10.23 ENSDART00000132556
ftr79
finTRIM family, member 79
chr7_-_66877058 10.19 ENSDART00000155954
adma
adrenomedullin a
chr6_+_49095646 9.93 ENSDART00000103385
slc25a55a
solute carrier family 25, member 55a
chr1_+_58282449 9.87 ENSDART00000131475
si:dkey-222h21.7
si:dkey-222h21.7
chr6_+_43450221 9.82 ENSDART00000075521
zgc:113054
zgc:113054
chr2_-_27900518 9.80 ENSDART00000109561
ENSDART00000077720
zgc:163121
zgc:163121
chr25_+_26441054 9.71 ENSDART00000158607
dapk2b
death-associated protein kinase 2b
chr23_-_5783421 9.49 ENSDART00000131521
ENSDART00000019455
csrp1a
cysteine and glycine-rich protein 1a
chr6_-_19168640 9.41 ENSDART00000163183
si:ch211-188c18.1
si:ch211-188c18.1
chr3_-_28828569 9.37 ENSDART00000167679
si:ch211-76l23.4
si:ch211-76l23.4
chr20_-_13673566 9.32 ENSDART00000181641
TAGAP
si:ch211-122h15.4
chr7_+_22688781 9.09 ENSDART00000173509
ugt5g1
UDP glucuronosyltransferase 5 family, polypeptide G1
chr8_+_23639124 8.88 ENSDART00000083108
nt5dc2
5'-nucleotidase domain containing 2
chr19_+_43780970 8.75 ENSDART00000063870
rpl11
ribosomal protein L11
chr17_+_25849332 8.55 ENSDART00000191994
acss1
acyl-CoA synthetase short chain family member 1
chr5_+_66170479 8.53 ENSDART00000172117
gldc
glycine dehydrogenase (decarboxylating)
chr11_+_10975012 8.46 ENSDART00000192872
itgb6
integrin, beta 6
chr7_+_24520518 8.08 ENSDART00000173604
btr09
bloodthirsty-related gene family, member 9
chr4_+_25607743 8.07 ENSDART00000028297
acot14
acyl-CoA thioesterase 14
chr23_-_1017605 7.94 ENSDART00000138290
cdh26.1
cadherin 26, tandem duplicate 1
chr5_+_9408901 7.89 ENSDART00000193364
FP236810.1

chr16_-_48400639 7.89 ENSDART00000159372
eif3ha
eukaryotic translation initiation factor 3, subunit H, a
chr10_+_38512270 7.81 ENSDART00000109752
serpinh1a
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a
chr7_+_26049818 7.69 ENSDART00000173611
si:dkey-6n21.12
si:dkey-6n21.12
chr21_-_19919020 7.67 ENSDART00000147396
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr8_+_25629722 7.43 ENSDART00000026807
wasa
Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a
chr16_+_35595312 7.23 ENSDART00000170438
si:ch211-1i11.3
si:ch211-1i11.3
chr20_-_43663494 7.15 ENSDART00000144564
BX470188.1

chr14_+_4796168 7.11 ENSDART00000041468
ap1ar
adaptor-related protein complex 1 associated regulatory protein
chr19_+_48176745 7.10 ENSDART00000164963
prdm1b
PR domain containing 1b, with ZNF domain
chr8_+_25629941 7.10 ENSDART00000186925
wasa
Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a
chr23_-_1017428 6.98 ENSDART00000110588
ENSDART00000183158
cdh26.1
cadherin 26, tandem duplicate 1
chr6_+_59913147 6.94 ENSDART00000156543
aamp
angio-associated, migratory cell protein
chr12_-_16435150 6.92 ENSDART00000086211
pcgf5b
polycomb group ring finger 5b
chr5_-_29570141 6.91 ENSDART00000043259
entpd2a.2
ectonucleoside triphosphate diphosphohydrolase 2a, tandem duplicate 2
chr4_+_77808579 6.82 ENSDART00000166325
si:dkey-238k10.3
si:dkey-238k10.3
chr23_+_11347313 6.50 ENSDART00000135406
chl1a
cell adhesion molecule L1-like a
chr6_-_43283122 6.47 ENSDART00000186022
frmd4ba
FERM domain containing 4Ba
chr11_+_42641404 6.30 ENSDART00000172641
ENSDART00000169938
il17rd
interleukin 17 receptor D
chr20_+_52546186 6.22 ENSDART00000110777
ENSDART00000153377
ENSDART00000153013
ENSDART00000042704
eef1db
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr16_-_9423735 5.95 ENSDART00000185645
ccr8.1
chemokine (C-C motif) receptor 8.1
chr3_-_58205045 5.94 ENSDART00000130740
si:ch211-256e16.11
si:ch211-256e16.11
chr4_-_1914228 5.90 ENSDART00000087835
ano6
anoctamin 6
chr22_-_10110959 5.86 ENSDART00000031005
ENSDART00000147580
gls2b
glutaminase 2b (liver, mitochondrial)
chr8_+_7322465 5.84 ENSDART00000192380
ssuh2rs1
ssu-2 homolog, related sequence 1
chr23_+_4483083 5.80 ENSDART00000092389
nup210
nucleoporin 210
chr5_-_6508250 5.65 ENSDART00000060535
crybb3
crystallin, beta B3
chr5_+_8196264 5.55 ENSDART00000174564
ENSDART00000161261
lmbrd2a
LMBR1 domain containing 2a
chr8_-_4694458 5.45 ENSDART00000019828
zgc:63587
zgc:63587
chr6_+_13046720 5.34 ENSDART00000165896
casp8
caspase 8, apoptosis-related cysteine peptidase
chr21_+_11139175 5.30 ENSDART00000169024
agxt2
alanine--glyoxylate aminotransferase 2
chr11_+_25328199 5.10 ENSDART00000141478
ENSDART00000112209
fam83d
family with sequence similarity 83, member D
chr12_-_33789218 5.09 ENSDART00000193258
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr11_+_6281647 4.99 ENSDART00000002459
ctns
cystinosin, lysosomal cystine transporter
chr3_-_49815223 4.97 ENSDART00000181208
gcgra
glucagon receptor a
chr11_+_2434262 4.96 ENSDART00000166445
csnk2a4
casein kinase 2, alpha 4 polypeptide
chr5_-_33039670 4.95 ENSDART00000141361
glipr2
GLI pathogenesis-related 2
chr3_+_35812040 4.94 ENSDART00000075903
ENSDART00000147712
crlf3
cytokine receptor-like factor 3
chr13_-_25745089 4.86 ENSDART00000189333
ENSDART00000147420
sgpl1
sphingosine-1-phosphate lyase 1
chr20_-_26936887 4.86 ENSDART00000160827
ftr79
finTRIM family, member 79
chr12_+_48784731 4.82 ENSDART00000158348
zmiz1b
zinc finger, MIZ-type containing 1b
chr18_+_44769027 4.77 ENSDART00000145190
ilvbl
ilvB (bacterial acetolactate synthase)-like
chr23_+_11285662 4.77 ENSDART00000111028
chl1a
cell adhesion molecule L1-like a
chr18_+_14619544 4.74 ENSDART00000010821
utp4
UTP4, small subunit processome component
chr13_+_25421531 4.61 ENSDART00000158093
calhm2
calcium homeostasis modulator 2
chr16_-_12491901 4.60 ENSDART00000174467
slc2a3b
solute carrier family 2 (facilitated glucose transporter), member 3b
chr3_+_3992590 4.60 ENSDART00000180211
ENSDART00000054840
BX005421.2

chr22_+_2598998 4.57 ENSDART00000176665
CU570894.1

chr4_-_62206968 4.57 ENSDART00000193074
si:dkeyp-35e5.5
si:dkeyp-35e5.5
chr25_-_4530085 4.56 ENSDART00000144907
pidd1
p53-induced death domain protein 1
chr15_-_25094026 4.53 ENSDART00000129154
exo5
exonuclease 5
chr4_+_59246094 4.51 ENSDART00000160587
si:dkey-105i14.1
si:dkey-105i14.1
chr4_-_71554068 4.50 ENSDART00000167414
si:dkey-27n6.1
si:dkey-27n6.1
chr23_-_33775145 4.42 ENSDART00000132147
ENSDART00000027959
ENSDART00000160116
racgap1
Rac GTPase activating protein 1
chr10_+_8554929 4.41 ENSDART00000190849
tbc1d10ab
TBC1 domain family, member 10Ab
chr15_-_25093680 4.39 ENSDART00000062695
exo5
exonuclease 5
chr15_+_28175638 4.34 ENSDART00000037119
slc46a1
solute carrier family 46 (folate transporter), member 1
chr8_+_15277874 4.27 ENSDART00000146965
dnttip2
deoxynucleotidyltransferase, terminal, interacting protein 2
chr1_+_58375871 4.26 ENSDART00000166736
CU914631.1

chr5_-_69804433 4.25 ENSDART00000028954
rilpl2
Rab interacting lysosomal protein-like 2
chr20_-_40367493 4.14 ENSDART00000075096
smpdl3a
sphingomyelin phosphodiesterase, acid-like 3A
chr3_-_11040575 4.11 ENSDART00000159802
CR382337.2

chr1_+_52662203 4.09 ENSDART00000141530
osbp
oxysterol binding protein
chr13_-_9300299 3.92 ENSDART00000144142
HTRA2 (1 of many)
si:dkey-33c12.12
chr5_-_323712 3.78 ENSDART00000188793
HOOK3
hook microtubule tethering protein 3
chr20_+_7398090 3.71 ENSDART00000108649
pcsk9
proprotein convertase subtilisin/kexin type 9
chr18_-_16924221 3.67 ENSDART00000122102
wee1
WEE1 G2 checkpoint kinase
chr7_-_20464133 3.65 ENSDART00000078192
cnpy4
canopy4
chr22_+_9793923 3.64 ENSDART00000063323
si:dkey-102c8.2
si:dkey-102c8.2
chr4_+_34418211 3.62 ENSDART00000160070
si:ch211-246b8.2
si:ch211-246b8.2
chr16_-_30931651 3.60 ENSDART00000132643
slc45a4
solute carrier family 45, member 4
chr25_+_35058088 3.57 ENSDART00000156838
zgc:112234
zgc:112234
chr1_-_11596829 3.56 ENSDART00000140725
si:dkey-26i13.7
si:dkey-26i13.7
chr13_-_36049008 3.55 ENSDART00000189978
lgmn
legumain
chr16_+_40508882 3.53 ENSDART00000126129
nagpa
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr16_+_20496691 3.51 ENSDART00000182737
ENSDART00000078984
cpvl
carboxypeptidase, vitellogenic-like
chr25_-_35136267 3.44 ENSDART00000109751
zgc:173585
zgc:173585
chr13_-_50567658 3.38 ENSDART00000132281
blnk
B cell linker
chr4_-_40589466 3.37 ENSDART00000133295
ENSDART00000124872
si:dkey-207m2.4
si:dkey-207m2.4
chr12_+_27537357 3.32 ENSDART00000136212
etv4
ets variant 4
chr15_-_18067220 3.29 ENSDART00000113142
phldb1b
pleckstrin homology-like domain, family B, member 1b
chr24_-_17039638 3.27 ENSDART00000048823
c8g
complement component 8, gamma polypeptide
chr23_-_5759242 3.22 ENSDART00000055087
phlda3
pleckstrin homology-like domain, family A, member 3
chr1_-_18592068 3.18 ENSDART00000082063
fam114a1
family with sequence similarity 114, member A1
chr9_+_50110763 3.15 ENSDART00000162990
cobll1b
cordon-bleu WH2 repeat protein-like 1b
chr4_+_77839900 3.08 ENSDART00000162243
si:dkey-207m2.4
si:dkey-207m2.4
chr11_-_37693019 3.05 ENSDART00000102898
zgc:158258
zgc:158258
chr13_-_45201300 3.04 ENSDART00000074750
ENSDART00000180265
runx3
runt-related transcription factor 3
chr18_+_2554666 3.02 ENSDART00000167218
p2ry2.1
purinergic receptor P2Y2, tandem duplicate 1
chr4_+_59245846 2.88 ENSDART00000104921
si:dkey-105i14.1
si:dkey-105i14.1
chr4_-_34455848 2.87 ENSDART00000184208
si:ch211-64i20.3
si:ch211-64i20.3
chr3_-_34082283 2.83 ENSDART00000151264
ighv4-3
immunoglobulin heavy variable 4-3
chr22_+_37888249 2.68 ENSDART00000076082
fetub
fetuin B
chr11_-_13618412 2.62 ENSDART00000137289
sid1
secreted immunoglobulin domain 1
chr6_-_7109063 2.60 ENSDART00000148548
nhej1
nonhomologous end-joining factor 1
chr22_+_2632961 2.58 ENSDART00000106278
znf1173
zinc finger protein 1173
chr19_+_41551543 2.52 ENSDART00000112364
si:ch211-57n23.4
si:ch211-57n23.4
chr3_+_24556640 2.49 ENSDART00000159405
sp100.2
SP110 nuclear body protein, tandem duplicate 2
chr15_-_252813 2.46 ENSDART00000163441
limk1a
LIM domain kinase 1a
chr7_+_49877148 2.43 ENSDART00000174182
slc1a2a
solute carrier family 1 (glial high affinity glutamate transporter), member 2a
chr14_+_22132896 2.42 ENSDART00000138274
ccng1
cyclin G1
chr15_+_29362714 2.40 ENSDART00000099916
ENSDART00000126196
gucy2f
guanylate cyclase 2F, retinal
chr5_+_57924611 2.38 ENSDART00000050949
btg4
B-cell translocation gene 4
chr23_-_15090782 2.33 ENSDART00000133624
si:ch211-218g4.2
si:ch211-218g4.2
chr19_+_34274504 2.30 ENSDART00000132046
si:ch211-9n13.3
si:ch211-9n13.3
chr7_+_54260004 2.26 ENSDART00000171909
pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr5_-_1999417 2.23 ENSDART00000155437
ENSDART00000145781
si:ch211-160e1.5
si:ch211-160e1.5
chr11_+_38429319 2.16 ENSDART00000029157
mfsd4aa
major facilitator superfamily domain containing 4Aa
chr4_-_44508975 2.12 ENSDART00000180528
si:dkeyp-100h4.1
si:dkeyp-100h4.1
chr5_-_63286077 2.09 ENSDART00000131274
tbcelb
tubulin folding cofactor E-like b
chr21_-_41065369 1.96 ENSDART00000143749
larsb
leucyl-tRNA synthetase b
chr19_+_25154066 1.89 ENSDART00000163220
si:ch211-239d6.2
si:ch211-239d6.2
chr12_+_34768106 1.85 ENSDART00000126420
ENSDART00000174433
slc38a10
solute carrier family 38, member 10
chr16_-_30931468 1.84 ENSDART00000187838
slc45a4
solute carrier family 45, member 4
chr7_-_2004159 1.82 ENSDART00000181965
ENSDART00000173821
zgc:171424
zgc:171424
zgc:171424
zgc:171424
chr8_-_30338872 1.73 ENSDART00000137583
dock8
dedicator of cytokinesis 8
chr15_+_29113616 1.57 ENSDART00000190015
ENSDART00000191099
capns1b
calpain, small subunit 1 b
chr19_+_2726819 1.56 ENSDART00000187122
ENSDART00000112414
rapgef5a
Rap guanine nucleotide exchange factor (GEF) 5a
chr20_-_45708962 1.54 ENSDART00000124283
gpcpd1
glycerophosphocholine phosphodiesterase 1
chr15_+_1134870 1.46 ENSDART00000155392
p2ry13
purinergic receptor P2Y13
chr23_-_24047054 1.45 ENSDART00000184308
ENSDART00000185902
CR925720.1

chr18_+_33340868 1.45 ENSDART00000099139
v2rh14
vomeronasal 2 receptor, h14
chr3_-_47294365 1.43 ENSDART00000191039
tnfsf18
TNF superfamily member 18
chr3_+_61420079 1.40 ENSDART00000168990
FP340292.1

chr4_+_13931578 1.34 ENSDART00000142466
pphln1
periphilin 1
chr7_-_16237861 1.33 ENSDART00000173647
btr07
bloodthirsty-related gene family, member 7
chr7_-_8438657 1.32 ENSDART00000173054
si:dkeyp-32g11.8
si:dkeyp-32g11.8
chr10_+_8629275 1.31 ENSDART00000129643
aplnrb
apelin receptor b
chr22_+_1947494 1.28 ENSDART00000159121
si:dkey-15h8.15
si:dkey-15h8.15
chr4_-_44509477 1.25 ENSDART00000102949
ENSDART00000135262
si:dkeyp-100h4.1
si:dkeyp-100h4.1
chr8_-_47818282 1.20 ENSDART00000137149
kank3
KN motif and ankyrin repeat domains 3
chr8_-_48770603 1.15 ENSDART00000159712
pimr184
Pim proto-oncogene, serine/threonine kinase, related 184
chr1_-_9134045 1.12 ENSDART00000142132
palb2
partner and localizer of BRCA2

Network of associatons between targets according to the STRING database.

First level regulatory network of tp53

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 19.5 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
3.9 15.5 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
3.8 11.5 GO:0032197 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
3.8 15.2 GO:0055107 Golgi to secretory granule transport(GO:0055107)
3.1 15.7 GO:0010719 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
2.7 24.3 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
2.6 7.7 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
2.5 15.2 GO:0070254 mucus secretion(GO:0070254)
2.4 12.2 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
2.3 16.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
2.1 29.9 GO:0050892 intestinal absorption(GO:0050892)
2.1 8.5 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
2.0 5.9 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
1.8 5.3 GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism(GO:0043903)
1.8 7.1 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
1.4 8.5 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
1.3 7.7 GO:0035332 positive regulation of hippo signaling(GO:0035332)
1.2 4.8 GO:0009097 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
1.2 6.9 GO:0033986 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
1.0 9.9 GO:0015800 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
1.0 14.5 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.9 3.5 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.7 5.9 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.7 10.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.7 21.3 GO:0051014 actin filament severing(GO:0051014)
0.7 23.6 GO:0003094 glomerular filtration(GO:0003094)
0.7 1.3 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.7 19.6 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.5 6.9 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.5 7.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.5 25.7 GO:0045785 positive regulation of cell adhesion(GO:0045785)
0.5 5.1 GO:1902808 positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.4 33.2 GO:0007596 blood coagulation(GO:0007596)
0.4 12.1 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.4 4.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.4 8.8 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.3 13.3 GO:0030199 collagen fibril organization(GO:0030199)
0.3 4.3 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.3 4.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.3 6.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.3 14.5 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.3 19.2 GO:0006414 translational elongation(GO:0006414)
0.3 3.2 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.3 7.9 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.3 12.6 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.3 8.4 GO:0036297 interstrand cross-link repair(GO:0036297)
0.2 16.5 GO:0030048 actin filament-based movement(GO:0030048)
0.2 0.9 GO:0060585 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.2 2.3 GO:0014028 notochord formation(GO:0014028)
0.2 12.4 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.2 1.1 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.2 13.1 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.2 3.3 GO:0035108 limb morphogenesis(GO:0035108)
0.2 4.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.2 2.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.2 5.8 GO:0042476 odontogenesis(GO:0042476)
0.2 14.9 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.2 4.9 GO:0046466 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.1 2.5 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 13.1 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 0.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 5.0 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.1 1.4 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 1.1 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 5.5 GO:0071875 adrenergic receptor signaling pathway(GO:0071875)
0.1 10.0 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.1 2.6 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.1 5.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.1 4.4 GO:0000281 mitotic cytokinesis(GO:0000281)
0.1 2.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 8.6 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.1 17.1 GO:0048925 sensory system development(GO:0048880) lateral line system development(GO:0048925)
0.1 8.2 GO:0002250 adaptive immune response(GO:0002250)
0.1 9.4 GO:0010942 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.1 3.0 GO:0002062 chondrocyte differentiation(GO:0002062)
0.1 1.5 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 14.7 GO:0045597 positive regulation of cell differentiation(GO:0045597)
0.1 14.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 3.7 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 5.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 3.7 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 6.0 GO:0060326 cell chemotaxis(GO:0060326)
0.0 2.2 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.6 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 4.2 GO:0006334 nucleosome assembly(GO:0006334)
0.0 31.4 GO:0016567 protein ubiquitination(GO:0016567)
0.0 2.5 GO:0051607 defense response to virus(GO:0051607)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 2.7 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 12.1 GO:0098609 cell-cell adhesion(GO:0098609)
0.0 2.4 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 18.1 GO:0030097 hemopoiesis(GO:0030097)
0.0 7.1 GO:0045165 cell fate commitment(GO:0045165)
0.0 0.8 GO:0001966 thigmotaxis(GO:0001966)
0.0 1.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 1.2 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 3.0 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 8.4 GO:0061061 muscle structure development(GO:0061061)
0.0 2.6 GO:0009617 response to bacterium(GO:0009617)
0.0 4.1 GO:0006869 lipid transport(GO:0006869)
0.0 6.3 GO:0006915 apoptotic process(GO:0006915)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 19.6 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
2.8 8.5 GO:0005960 glycine cleavage complex(GO:0005960)
1.6 4.8 GO:0005948 acetolactate synthase complex(GO:0005948)
1.5 12.2 GO:0001772 immunological synapse(GO:0001772)
0.9 6.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.8 2.4 GO:0044316 cone cell pedicle(GO:0044316)
0.8 7.9 GO:0042788 polysomal ribosome(GO:0042788)
0.5 2.6 GO:0032807 DNA ligase IV complex(GO:0032807)
0.5 7.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.4 5.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.4 5.1 GO:0097431 mitotic spindle pole(GO:0097431)
0.4 26.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.4 18.7 GO:0005902 microvillus(GO:0005902)
0.4 41.9 GO:0030027 lamellipodium(GO:0030027)
0.4 15.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.4 48.9 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.3 14.9 GO:0016342 catenin complex(GO:0016342)
0.3 6.9 GO:0035102 PRC1 complex(GO:0035102)
0.3 4.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 11.0 GO:0031941 filamentous actin(GO:0031941)
0.2 14.5 GO:0005884 actin filament(GO:0005884)
0.2 16.5 GO:0016459 myosin complex(GO:0016459)
0.2 46.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.2 4.7 GO:0030686 90S preribosome(GO:0030686)
0.2 5.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 12.1 GO:0030141 secretory granule(GO:0030141)
0.1 3.3 GO:0045180 basal cortex(GO:0045180)
0.1 9.5 GO:0030018 Z disc(GO:0030018)
0.1 19.2 GO:0009986 cell surface(GO:0009986)
0.1 7.3 GO:0031901 early endosome membrane(GO:0031901)
0.1 5.8 GO:0005643 nuclear pore(GO:0005643)
0.1 23.7 GO:0000785 chromatin(GO:0000785)
0.1 76.6 GO:0005615 extracellular space(GO:0005615)
0.0 2.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 4.2 GO:0036064 ciliary basal body(GO:0036064)
0.0 5.0 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 14.8 GO:0031966 mitochondrial membrane(GO:0031966)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 19.5 GO:1901612 cardiolipin binding(GO:1901612)
5.1 25.7 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
4.1 16.3 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
3.0 8.9 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
2.4 12.2 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
1.7 5.0 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
1.6 4.8 GO:0003984 acetolactate synthase activity(GO:0003984)
1.4 8.5 GO:0003987 acetate-CoA ligase activity(GO:0003987)
1.2 4.9 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
1.2 36.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
1.1 3.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
1.0 9.9 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
1.0 5.0 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.9 15.7 GO:0045159 myosin II binding(GO:0045159)
0.9 4.3 GO:0005542 folic acid binding(GO:0005542)
0.8 21.7 GO:0042805 actinin binding(GO:0042805)
0.8 8.5 GO:0016594 glycine binding(GO:0016594)
0.7 3.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.7 5.9 GO:0004359 glutaminase activity(GO:0004359)
0.6 35.1 GO:0000146 microfilament motor activity(GO:0000146)
0.6 14.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.5 6.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.5 1.5 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.5 7.7 GO:2001069 glycogen binding(GO:2001069)
0.5 18.7 GO:0005518 collagen binding(GO:0005518)
0.5 11.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.5 26.4 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.4 1.8 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.4 19.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.4 7.9 GO:0070122 isopeptidase activity(GO:0070122)
0.4 8.6 GO:0048038 quinone binding(GO:0048038)
0.4 6.9 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.4 24.4 GO:0017124 SH3 domain binding(GO:0017124)
0.4 5.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.4 19.6 GO:0005178 integrin binding(GO:0005178)
0.4 1.1 GO:0048030 disaccharide binding(GO:0048030)
0.3 7.1 GO:0019894 kinesin binding(GO:0019894)
0.3 4.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.3 4.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.3 1.3 GO:0060182 apelin receptor activity(GO:0060182)
0.2 15.9 GO:0004521 endoribonuclease activity(GO:0004521)
0.2 0.9 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 23.9 GO:0004896 cytokine receptor activity(GO:0004896)
0.2 5.3 GO:0008483 transaminase activity(GO:0008483)
0.2 25.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 2.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 12.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 3.2 GO:0003785 actin monomer binding(GO:0003785)
0.2 32.1 GO:0046982 protein heterodimerization activity(GO:0046982)
0.2 4.1 GO:0015248 sterol transporter activity(GO:0015248)
0.2 14.5 GO:0008201 heparin binding(GO:0008201)
0.1 7.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 4.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 3.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 2.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.9 GO:0005549 olfactory receptor activity(GO:0004984) odorant binding(GO:0005549)
0.1 2.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.1 25.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 18.6 GO:0042802 identical protein binding(GO:0042802)
0.1 11.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 8.3 GO:0045296 cadherin binding(GO:0045296)
0.1 5.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 4.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 2.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 10.2 GO:0005179 hormone activity(GO:0005179)
0.1 2.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 16.6 GO:0051015 actin filament binding(GO:0051015)
0.1 12.6 GO:0005198 structural molecule activity(GO:0005198)
0.1 1.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 30.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 10.7 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.1 14.5 GO:0003779 actin binding(GO:0003779)
0.0 3.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.6 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.3 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 5.5 GO:0008134 transcription factor binding(GO:0008134)
0.0 10.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 2.6 GO:0043566 structure-specific DNA binding(GO:0043566)
0.0 5.1 GO:0019901 protein kinase binding(GO:0019901)
0.0 15.9 GO:0005525 GTP binding(GO:0005525)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 3.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 19.7 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 1.8 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 3.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.3 GO:0005543 phospholipid binding(GO:0005543)
0.0 0.4 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 19.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.8 20.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.8 25.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.8 5.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.7 13.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.6 14.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.4 3.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.4 16.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.3 4.9 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.3 15.7 PID P53 REGULATION PATHWAY p53 pathway
0.2 4.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 30.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.2 6.3 PID FGF PATHWAY FGF signaling pathway
0.2 3.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.2 2.4 PID CONE PATHWAY Visual signal transduction: Cones
0.1 2.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 14.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 3.3 PID LKB1 PATHWAY LKB1 signaling events
0.0 3.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 15.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
1.7 8.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
1.1 11.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.7 5.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.7 5.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.3 9.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.3 3.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.3 3.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.3 19.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 4.3 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.2 26.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 4.4 REACTOME KINESINS Genes involved in Kinesins
0.2 3.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.2 18.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 5.8 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 6.3 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.1 1.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 3.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.1 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.6 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 1.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.5 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis