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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for vsx1_shox_shox2_uncx4.1_lhx2a

Z-value: 0.92

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Transcription factors associated with vsx1_shox_shox2_uncx4.1_lhx2a

Gene Symbol Gene ID Gene Info
vsx1
ENSDARG00000056292 visual system homeobox 1 homolog, chx10-like
vsx1
ENSDARG00000109766 visual system homeobox 1 homolog, chx10-like
shox
ENSDARG00000025891 short stature homeobox
shox2
ENSDARG00000075713 short stature homeobox 2
uncx4.1
ENSDARG00000037760 Unc4.1 homeobox (C. elegans)
lhx2a
ENSDARG00000037964 LIM homeobox 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
uncx4.1dr11_v1_chr1_+_9290103_92901030.631.6e-11Click!
vsx1dr11_v1_chr17_-_21066075_210661050.405.8e-05Click!
shox2dr11_v1_chr15_-_2188332_21884220.321.8e-03Click!
lhx2adr11_v1_chr21_-_8422351_84223630.189.1e-02Click!
shoxdr11_v1_chr9_+_34641237_346412370.047.0e-01Click!

Activity profile of vsx1_shox_shox2_uncx4.1_lhx2a motif

Sorted Z-values of vsx1_shox_shox2_uncx4.1_lhx2a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_37903790 16.53 ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr18_-_40708537 13.05 ENSDART00000077577
si:ch211-132b12.8
si:ch211-132b12.8
chr2_+_50608099 13.01 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr11_-_44801968 12.83 ENSDART00000161846
map1lc3c
microtubule-associated protein 1 light chain 3 gamma
chr5_+_64732036 12.45 ENSDART00000073950
olfm1a
olfactomedin 1a
chr16_+_5774977 11.80 ENSDART00000134202
ccka
cholecystokinin a
chr15_+_22311803 10.82 ENSDART00000150182
hepacama
hepatic and glial cell adhesion molecule a
chr1_-_18811517 10.66 ENSDART00000142026
si:dkey-167i21.2
si:dkey-167i21.2
chr10_-_34915886 10.49 ENSDART00000141201
ENSDART00000002166
ccna1
cyclin A1
chr13_+_38430466 10.47 ENSDART00000132691
adgrb3
adhesion G protein-coupled receptor B3
chr9_-_35633827 10.45 ENSDART00000077745
zp2l1
zona pellucida glycoprotein 2, like 1
chr5_+_64732270 10.42 ENSDART00000134241
olfm1a
olfactomedin 1a
chr21_+_25777425 10.21 ENSDART00000021620
cldnd
claudin d
chr4_+_21129752 10.04 ENSDART00000169764
syt1a
synaptotagmin Ia
chr17_+_23298928 9.95 ENSDART00000153652
zgc:165461
zgc:165461
chr20_-_9436521 9.48 ENSDART00000133000
zgc:101840
zgc:101840
chr11_-_6452444 9.35 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
larp6b
La ribonucleoprotein domain family, member 6b
chr2_+_6253246 9.35 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr19_-_20113696 9.32 ENSDART00000188813
npy
neuropeptide Y
chr23_+_40460333 9.26 ENSDART00000184658
soga3b
SOGA family member 3b
chr20_+_18551657 8.85 ENSDART00000147001
si:dkeyp-72h1.1
si:dkeyp-72h1.1
chr16_+_39159752 8.83 ENSDART00000122081
sybu
syntabulin (syntaxin-interacting)
chr2_+_20332044 8.69 ENSDART00000112131
plppr4a
phospholipid phosphatase related 4a
chr10_-_21362071 8.66 ENSDART00000125167
avd
avidin
chr10_-_34916208 8.47 ENSDART00000187371
ccna1
cyclin A1
chr18_-_1185772 8.44 ENSDART00000143245
nptnb
neuroplastin b
chr20_-_28800999 7.96 ENSDART00000049462
rab15
RAB15, member RAS oncogene family
chr7_+_30787903 7.89 ENSDART00000174000
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr10_-_21362320 7.78 ENSDART00000189789
avd
avidin
chr20_-_23426339 7.47 ENSDART00000004625
zar1
zygote arrest 1
chr3_-_43356082 7.16 ENSDART00000171213
uncx
UNC homeobox
chr15_-_9272328 6.82 ENSDART00000172114
calm2a
calmodulin 2a (phosphorylase kinase, delta)
chr1_-_50859053 6.82 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr25_-_13842618 6.68 ENSDART00000160258
mapk8ip1a
mitogen-activated protein kinase 8 interacting protein 1a
chr10_-_25217347 6.63 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr18_+_24921587 6.61 ENSDART00000191345
rgma
repulsive guidance molecule family member a
chr24_+_12835935 6.53 ENSDART00000114762
nanog
nanog homeobox
chr24_-_21923930 6.43 ENSDART00000131944
tagln3b
transgelin 3b
chr12_+_24342303 6.42 ENSDART00000111239
nrxn1a
neurexin 1a
chr4_+_11384891 6.35 ENSDART00000092381
ENSDART00000186577
ENSDART00000191054
ENSDART00000191584
pcloa
piccolo presynaptic cytomatrix protein a
chr8_+_45334255 6.04 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr20_-_29420713 5.91 ENSDART00000147464
ryr3
ryanodine receptor 3
chr19_-_5103141 5.84 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr19_-_10243148 5.76 ENSDART00000148073
shisa7b
shisa family member 7
chr10_-_34002185 5.60 ENSDART00000046599
zar1l
zygote arrest 1-like
chr16_+_46111849 5.54 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr10_+_6884627 5.47 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr2_-_38284648 5.45 ENSDART00000148281
ENSDART00000132621
si:ch211-14a17.7
si:ch211-14a17.7
chr20_-_32110882 5.40 ENSDART00000030324
grm1a
glutamate receptor, metabotropic 1a
chr23_+_44741500 5.28 ENSDART00000166421
atp1b2a
ATPase Na+/K+ transporting subunit beta 2a
chr9_-_31278048 5.26 ENSDART00000022204
zic5
zic family member 5 (odd-paired homolog, Drosophila)
chr2_-_38287987 5.23 ENSDART00000185329
ENSDART00000061677
si:ch211-14a17.6
si:ch211-14a17.6
chr23_+_20563779 5.21 ENSDART00000146008
camkvl
CaM kinase-like vesicle-associated, like
chr15_-_22074315 5.21 ENSDART00000149830
drd2a
dopamine receptor D2a
chr20_+_19238382 5.18 ENSDART00000136757
fndc4a
fibronectin type III domain containing 4a
chr6_+_3828560 5.16 ENSDART00000185273
ENSDART00000179091
gad1b
glutamate decarboxylase 1b
chr24_+_40860320 5.15 ENSDART00000161351
gorasp1b
golgi reassembly stacking protein 1b
chr11_-_1550709 5.09 ENSDART00000110097
si:ch73-303b9.1
si:ch73-303b9.1
chr11_-_37509001 5.06 ENSDART00000109753
bsnb
bassoon (presynaptic cytomatrix protein) b
chr16_+_20161805 5.01 ENSDART00000192146
c16h2orf66
chromosome 16 C2orf66 homolog
chr17_-_12389259 4.95 ENSDART00000185724
snap25b
synaptosomal-associated protein, 25b
chr22_-_12160283 4.84 ENSDART00000146785
ENSDART00000128176
tmem163b
transmembrane protein 163b
chr6_+_39232245 4.84 ENSDART00000187351
b4galnt1b
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr8_-_33114202 4.66 ENSDART00000098840
ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr4_+_12615836 4.59 ENSDART00000003583
lmo3
LIM domain only 3
chr6_+_23887314 4.57 ENSDART00000163188
znf648
zinc finger protein 648
chr5_+_61301525 4.41 ENSDART00000128773
doc2b
double C2-like domains, beta
chr16_+_34531486 4.39 ENSDART00000043291
paqr7b
progestin and adipoQ receptor family member VII, b
chr21_+_28958471 4.38 ENSDART00000144331
ENSDART00000005929
ppp3ca
protein phosphatase 3, catalytic subunit, alpha isozyme
chr5_+_32247310 4.29 ENSDART00000182649
myha
myosin, heavy chain a
chr1_+_35985813 4.22 ENSDART00000179634
ENSDART00000139636
ENSDART00000175902
zgc:152968
zgc:152968
chr3_+_33341640 4.18 ENSDART00000186352
pyya
peptide YYa
chr5_-_12219572 4.17 ENSDART00000167834
nos1
nitric oxide synthase 1 (neuronal)
chr1_+_18811679 4.16 ENSDART00000078610
slc25a51a
solute carrier family 25, member 51a
chr9_-_20372977 4.15 ENSDART00000113418
igsf3
immunoglobulin superfamily, member 3
chr23_+_28582865 4.14 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr21_+_28478663 4.12 ENSDART00000077887
ENSDART00000134150
slc22a6l
solute carrier family 22 (organic anion transporter), member 6, like
chr9_-_32753535 3.99 ENSDART00000060006
olig2
oligodendrocyte lineage transcription factor 2
chr11_+_18183220 3.96 ENSDART00000113468
LO018315.10

chr19_-_32710922 3.92 ENSDART00000004034
hpca
hippocalcin
chr4_+_9467049 3.90 ENSDART00000012659
zgc:55888
zgc:55888
chr1_-_42778510 3.89 ENSDART00000190172
lrrtm1
leucine rich repeat transmembrane neuronal 1
chr11_+_30057762 3.85 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr7_+_32722227 3.83 ENSDART00000126565
si:ch211-150g13.3
si:ch211-150g13.3
chr8_-_50888806 3.69 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr8_+_16025554 3.66 ENSDART00000110171
elavl4
ELAV like neuron-specific RNA binding protein 4
chr12_+_18681477 3.65 ENSDART00000127981
ENSDART00000143979
rgs9b
regulator of G protein signaling 9b
chr21_+_34088110 3.62 ENSDART00000145123
ENSDART00000029599
ENSDART00000147519
mtmr1b
myotubularin related protein 1b
chr19_-_5103313 3.55 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr2_-_11512819 3.51 ENSDART00000142013
penka
proenkephalin a
chr9_-_43538328 3.51 ENSDART00000140526
znf385b
zinc finger protein 385B
chr24_+_16547035 3.51 ENSDART00000164319
sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr13_-_36911118 3.48 ENSDART00000048739
trim9
tripartite motif containing 9
chr16_+_2820340 3.42 ENSDART00000092299
ENSDART00000192931
ENSDART00000148512
si:dkey-288i20.2
si:dkey-288i20.2
chr21_-_39177564 3.41 ENSDART00000065143
unc119b
unc-119 homolog b (C. elegans)
chr19_-_32641725 3.38 ENSDART00000165006
ENSDART00000188185
hpca
hippocalcin
chr1_-_55248496 3.36 ENSDART00000098615
nanos3
nanos homolog 3
chr6_+_21001264 3.34 ENSDART00000044519
ENSDART00000151278
cx44.2
connexin 44.2
chr20_-_9462433 3.33 ENSDART00000152674
ENSDART00000040557
zgc:101840
zgc:101840
chr14_+_45406299 3.30 ENSDART00000173142
ENSDART00000112377
map1lc3cl
microtubule-associated protein 1 light chain 3 gamma, like
chr12_-_33579873 3.26 ENSDART00000184661
tdrkh
tudor and KH domain containing
chr16_-_42056137 3.19 ENSDART00000102798
zp3d.2
zona pellucida glycoprotein 3d tandem duplicate 2
chr6_-_12172424 3.16 ENSDART00000109344
tanc1a
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr19_-_42391383 3.16 ENSDART00000110075
ENSDART00000087002
plekho1a
pleckstrin homology domain containing, family O member 1a
chr25_-_20378721 3.12 ENSDART00000181707
kctd15a
potassium channel tetramerization domain containing 15a
chr14_+_25817628 3.10 ENSDART00000047680
glra1
glycine receptor, alpha 1
chr12_-_33972798 3.08 ENSDART00000105545
arl3
ADP-ribosylation factor-like 3
chr7_+_24023653 3.08 ENSDART00000141165
tinf2
TERF1 (TRF1)-interacting nuclear factor 2
chr2_-_30668580 3.07 ENSDART00000087270
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr19_+_21362553 3.03 ENSDART00000122002
tshz1
teashirt zinc finger homeobox 1
chr2_+_22702488 2.94 ENSDART00000076647
kif1ab
kinesin family member 1Ab
chr6_-_6487876 2.92 ENSDART00000137642
cep170ab
centrosomal protein 170Ab
chr20_-_6532462 2.92 ENSDART00000054653
mcm3l
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like
chr21_-_18648861 2.89 ENSDART00000112113
si:dkey-112m2.1
si:dkey-112m2.1
chr20_-_29864390 2.88 ENSDART00000161834
ENSDART00000132278
rnf144ab
ring finger protein 144ab
chr22_+_17261801 2.79 ENSDART00000192978
ENSDART00000193187
ENSDART00000179953
ENSDART00000134798
tdrd5
tudor domain containing 5
chr15_-_16098531 2.76 ENSDART00000080377
aldoca
aldolase C, fructose-bisphosphate, a
chr12_+_31744217 2.74 ENSDART00000190361
RNF157
si:dkey-49c17.3
chr9_-_12424791 2.73 ENSDART00000135447
ENSDART00000088199
zgc:162707
zgc:162707
chr25_-_27564205 2.72 ENSDART00000157319
hyal4
hyaluronoglucosaminidase 4
chr16_+_25116827 2.71 ENSDART00000163244
si:ch211-261d7.6
si:ch211-261d7.6
chr15_-_20024205 2.67 ENSDART00000161379
auts2b
autism susceptibility candidate 2b
chr7_+_23292133 2.65 ENSDART00000134489
htr2cl1
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1
chr21_+_34088377 2.65 ENSDART00000170070
mtmr1b
myotubularin related protein 1b
chr5_-_23280098 2.62 ENSDART00000126540
ENSDART00000051533
plp1b
proteolipid protein 1b
chr17_+_15433671 2.61 ENSDART00000149568
fabp7a
fatty acid binding protein 7, brain, a
chr19_-_20403507 2.59 ENSDART00000052603
ENSDART00000137590
dazl
deleted in azoospermia-like
chr21_+_32820175 2.59 ENSDART00000076903
adra2db
adrenergic, alpha-2D-, receptor b
chr20_-_48485354 2.58 ENSDART00000124040
ENSDART00000148437
insm1a
insulinoma-associated 1a
chr15_-_6247775 2.57 ENSDART00000148350
dscamb
Down syndrome cell adhesion molecule b
chr17_+_15433518 2.53 ENSDART00000026180
fabp7a
fatty acid binding protein 7, brain, a
chr7_-_23996133 2.51 ENSDART00000173761
si:dkey-183c6.8
si:dkey-183c6.8
chr21_-_42100471 2.51 ENSDART00000166148
gabra1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr9_-_44295071 2.50 ENSDART00000011837
neurod1
neuronal differentiation 1
chr16_-_29437373 2.48 ENSDART00000148405
si:ch211-113g11.6
si:ch211-113g11.6
chr10_+_6884123 2.47 ENSDART00000149095
ENSDART00000148772
ENSDART00000149334
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr7_-_28148310 2.45 ENSDART00000044208
lmo1
LIM domain only 1
chr2_-_15324837 2.45 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr20_+_41756996 2.43 ENSDART00000186393
fam184a
family with sequence similarity 184, member A
chr12_+_34953038 2.42 ENSDART00000187022
ENSDART00000123988
ENSDART00000027034
qki2
QKI, KH domain containing, RNA binding 2
chr23_+_28731379 2.40 ENSDART00000047378
cort
cortistatin
chr2_-_31936966 2.40 ENSDART00000169484
ENSDART00000192492
ENSDART00000027689
amph
amphiphysin
chr19_+_46158078 2.37 ENSDART00000183933
ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr11_-_29563437 2.34 ENSDART00000163958
arhgef10la
Rho guanine nucleotide exchange factor (GEF) 10-like a
chr5_-_15851953 2.29 ENSDART00000173101
si:dkey-1k23.3
si:dkey-1k23.3
chr5_-_68333081 2.28 ENSDART00000168786
h1m
linker histone H1M
chr16_-_29387215 2.27 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr4_-_17629444 2.25 ENSDART00000108814
nrip2
nuclear receptor interacting protein 2
chr25_+_14507567 2.25 ENSDART00000015681
dbx1b
developing brain homeobox 1b
chr20_-_39271844 2.24 ENSDART00000192708
clu
clusterin
chr4_+_3980247 2.24 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr14_-_8940499 2.24 ENSDART00000129030
zgc:153681
zgc:153681
chr6_-_38419318 2.23 ENSDART00000138026
gabra5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr22_+_17828267 2.21 ENSDART00000136016
hapln4
hyaluronan and proteoglycan link protein 4
chr7_-_30174882 2.20 ENSDART00000110409
frmd5
FERM domain containing 5
chr12_+_41697664 2.20 ENSDART00000162302
bnip3
BCL2 interacting protein 3
chr14_-_34026316 2.19 ENSDART00000186062
cyfip2
cytoplasmic FMR1 interacting protein 2
chr4_-_15420452 2.18 ENSDART00000016230
plxna4
plexin A4
chr18_+_10884996 2.17 ENSDART00000147613
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr6_-_41229787 2.17 ENSDART00000065013
synpr
synaptoporin
chr21_-_25573064 2.13 ENSDART00000134310
CR388166.1

chr20_+_30445971 2.12 ENSDART00000153150
myt1la
myelin transcription factor 1-like, a
chr11_+_24620742 2.07 ENSDART00000182471
ENSDART00000048365
syt6b
synaptotagmin VIb
chr19_-_27261102 2.06 ENSDART00000143919
gabbr1b
gamma-aminobutyric acid (GABA) B receptor, 1b
chr5_+_30624183 2.06 ENSDART00000141444
abcg4a
ATP-binding cassette, sub-family G (WHITE), member 4a
chr7_+_29167744 2.05 ENSDART00000076345
slc38a8b
solute carrier family 38, member 8b
chr24_+_1023839 2.05 ENSDART00000082526
zgc:111976
zgc:111976
chr8_-_7232413 2.04 ENSDART00000092426
grip2a
glutamate receptor interacting protein 2a
chr7_-_24699985 2.04 ENSDART00000052802
calb2b
calbindin 2b
chr11_+_28476298 2.04 ENSDART00000122319
lrrc38b
leucine rich repeat containing 38b
chr10_-_21545091 2.03 ENSDART00000029122
ENSDART00000132207
zgc:165539
zgc:165539
chr8_+_11325310 2.02 ENSDART00000142577
fxn
frataxin
chr22_-_20166660 1.98 ENSDART00000085913
ENSDART00000188241
btbd2a
BTB (POZ) domain containing 2a
chr2_-_3678029 1.95 ENSDART00000146861
mmp16b
matrix metallopeptidase 16b (membrane-inserted)
chr19_-_7358184 1.95 ENSDART00000092379
oxr1b
oxidation resistance 1b
chr3_+_34919810 1.95 ENSDART00000055264
ca10b
carbonic anhydrase Xb
chr19_+_22062202 1.94 ENSDART00000100181
sall3b
spalt-like transcription factor 3b
chr20_+_52554352 1.94 ENSDART00000153217
ENSDART00000145230
eef1db
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr10_-_20696518 1.94 ENSDART00000064581
kcnip3b
Kv channel interacting protein 3b, calsenilin
chr17_+_24722646 1.92 ENSDART00000138356
mtfr1l
mitochondrial fission regulator 1-like
chr20_-_28642061 1.92 ENSDART00000135513
rgs6
regulator of G protein signaling 6
chr21_+_39705483 1.91 ENSDART00000147718
ENSDART00000168996
plrdgb
PITP-less RdgB-like protein
chr5_+_32206378 1.91 ENSDART00000126873
ENSDART00000051361
myhz2
myosin, heavy polypeptide 2, fast muscle specific
chr13_-_37545487 1.90 ENSDART00000131269
syt16
synaptotagmin XVI
chr17_+_19630272 1.88 ENSDART00000104895
rgs7a
regulator of G protein signaling 7a
chr11_-_30158191 1.88 ENSDART00000155278
ENSDART00000156121
scml2
Scm polycomb group protein like 2
chr16_+_47207691 1.85 ENSDART00000062507
ica1
islet cell autoantigen 1
chr13_+_38817871 1.85 ENSDART00000187708
col19a1
collagen, type XIX, alpha 1
chr19_-_30510259 1.84 ENSDART00000135128
ENSDART00000186169
ENSDART00000182974
ENSDART00000187797
bag6l
BCL2 associated athanogene 6, like
chr5_+_21144269 1.82 ENSDART00000028087
cds2
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
chr4_-_77125693 1.81 ENSDART00000174256
CU467646.3

chr21_+_42226113 1.81 ENSDART00000170362
GABRB2 (1 of many)
gamma-aminobutyric acid type A receptor beta2 subunit
chr10_-_26744131 1.80 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fgf13b
fibroblast growth factor 13b
chr17_-_29119362 1.79 ENSDART00000104204
foxg1a
forkhead box G1a
chr3_-_36932515 1.78 ENSDART00000111981
ENSDART00000188470
cntnap1
contactin associated protein 1
chr3_+_28860283 1.78 ENSDART00000077235
alg1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr18_+_17827149 1.78 ENSDART00000190237
ENSDART00000189345
ZNF423
si:ch211-216l23.1
chr4_-_14315855 1.77 ENSDART00000133325
nell2b
neural EGFL like 2b
chr16_-_12173554 1.76 ENSDART00000110567
ENSDART00000155935
clstn3
calsyntenin 3
chr3_-_46811611 1.76 ENSDART00000134092
elavl3
ELAV like neuron-specific RNA binding protein 3

Network of associatons between targets according to the STRING database.

First level regulatory network of vsx1_shox_shox2_uncx4.1_lhx2a

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 22.9 GO:0061075 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
2.3 9.4 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
2.3 9.3 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
2.2 8.8 GO:0060074 synapse maturation(GO:0060074)
2.1 10.5 GO:0016322 neuron remodeling(GO:0016322)
2.0 10.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
1.7 5.2 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
1.4 4.2 GO:0098924 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
1.4 23.2 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
1.3 6.6 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
1.3 12.6 GO:1904071 presynaptic active zone assembly(GO:1904071)
1.2 1.2 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
1.0 3.1 GO:0071361 cellular response to ethanol(GO:0071361)
1.0 4.0 GO:0021742 abducens nucleus development(GO:0021742)
0.8 16.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.8 3.4 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.8 6.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.8 5.3 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.7 2.2 GO:0007414 axonal defasciculation(GO:0007414)
0.7 2.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.7 14.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.6 3.6 GO:0060967 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.6 1.1 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.6 6.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.5 2.6 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.5 2.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.5 1.5 GO:0035902 response to immobilization stress(GO:0035902)
0.5 2.0 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.5 2.5 GO:0070208 protein heterotrimerization(GO:0070208)
0.5 1.4 GO:0097378 interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
0.5 1.4 GO:0045887 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.4 2.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.4 12.6 GO:0070593 dendrite self-avoidance(GO:0070593)
0.4 7.3 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.4 3.4 GO:1900186 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.4 2.9 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.4 2.9 GO:1902292 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.4 8.6 GO:0008406 gonad development(GO:0008406)
0.4 1.2 GO:0060986 negative regulation of peptide secretion(GO:0002792) regulation of endocrine process(GO:0044060) endocrine hormone secretion(GO:0060986) negative regulation of peptide hormone secretion(GO:0090278)
0.4 5.4 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.4 5.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.4 19.2 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.4 5.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.3 1.4 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.3 1.2 GO:1901017 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.3 1.5 GO:0071422 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.3 5.3 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.3 4.4 GO:0001556 oocyte maturation(GO:0001556)
0.3 2.9 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.3 1.1 GO:0001774 microglial cell activation(GO:0001774) regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.3 4.2 GO:0007631 feeding behavior(GO:0007631)
0.3 1.0 GO:0015677 copper ion import(GO:0015677)
0.3 3.1 GO:0001964 startle response(GO:0001964)
0.3 0.8 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.2 3.7 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.2 8.0 GO:0032482 Rab protein signal transduction(GO:0032482)
0.2 0.7 GO:0006089 lactate metabolic process(GO:0006089)
0.2 10.8 GO:0007586 digestion(GO:0007586)
0.2 8.6 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.2 2.2 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.2 1.2 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.2 1.1 GO:0000012 single strand break repair(GO:0000012)
0.2 1.1 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.2 3.1 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.2 2.7 GO:0048512 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.2 2.7 GO:0007143 female meiotic division(GO:0007143)
0.2 1.4 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 1.8 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.2 8.8 GO:0060968 regulation of gene silencing(GO:0060968)
0.2 1.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 1.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.2 1.3 GO:0070207 protein homotrimerization(GO:0070207)
0.2 3.0 GO:0007340 acrosome reaction(GO:0007340)
0.2 3.1 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.2 2.3 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.2 4.1 GO:0045773 positive regulation of axon extension(GO:0045773)
0.2 1.8 GO:0032288 myelin assembly(GO:0032288)
0.2 0.5 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011)
0.2 5.4 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.2 13.4 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.2 4.7 GO:0006829 zinc II ion transport(GO:0006829)
0.2 1.1 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.2 1.5 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.4 GO:0010662 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.1 2.4 GO:0045761 regulation of cAMP metabolic process(GO:0030814) regulation of cAMP biosynthetic process(GO:0030817) regulation of adenylate cyclase activity(GO:0045761)
0.1 3.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 3.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 0.7 GO:0034505 tooth mineralization(GO:0034505)
0.1 0.4 GO:2000434 regulation of protein neddylation(GO:2000434)
0.1 0.5 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.1 0.8 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.1 1.8 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.4 GO:0021527 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519) spinal cord association neuron differentiation(GO:0021527)
0.1 1.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 2.2 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.1 4.1 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 2.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.3 GO:0021512 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.1 2.0 GO:0008354 germ cell migration(GO:0008354)
0.1 7.1 GO:0046328 regulation of JNK cascade(GO:0046328)
0.1 0.4 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 0.4 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.1 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.7 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 7.9 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 9.0 GO:1902284 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.1 3.2 GO:0030073 insulin secretion(GO:0030073)
0.1 2.3 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 3.7 GO:0000266 mitochondrial fission(GO:0000266)
0.1 0.6 GO:0003232 bulbus arteriosus development(GO:0003232)
0.1 1.5 GO:0099590 positive regulation of synaptic transmission, glutamatergic(GO:0051968) neurotransmitter receptor internalization(GO:0099590)
0.1 0.8 GO:0043090 amino acid import(GO:0043090) L-amino acid import(GO:0043092)
0.1 0.3 GO:0032099 negative regulation of response to food(GO:0032096) regulation of appetite(GO:0032098) negative regulation of appetite(GO:0032099)
0.1 1.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.5 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.9 GO:0042044 fluid transport(GO:0042044)
0.1 1.0 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 0.5 GO:0021767 mammillary body development(GO:0021767)
0.1 0.3 GO:0019532 oxalate transport(GO:0019532)
0.1 8.4 GO:0010506 regulation of autophagy(GO:0010506)
0.1 0.7 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.1 0.8 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.6 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 1.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 1.1 GO:0007254 JNK cascade(GO:0007254)
0.1 0.2 GO:0030889 negative regulation of B cell proliferation(GO:0030889) negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645) negative regulation of B cell activation(GO:0050869)
0.1 0.6 GO:0060118 reflex(GO:0060004) vestibular reflex(GO:0060005) vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.1 0.6 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.8 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.1 1.0 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 4.2 GO:0006414 translational elongation(GO:0006414)
0.1 1.2 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.1 0.8 GO:0045471 response to ethanol(GO:0045471)
0.1 0.6 GO:0006465 signal peptide processing(GO:0006465)
0.1 2.4 GO:0060037 pharyngeal system development(GO:0060037)
0.1 1.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 5.1 GO:0007030 Golgi organization(GO:0007030)
0.1 5.5 GO:0017148 negative regulation of translation(GO:0017148)
0.1 1.0 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 2.0 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.1 1.8 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1 0.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.8 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.2 GO:0048890 epidermal cell fate specification(GO:0009957) lateral line ganglion development(GO:0048890)
0.0 0.8 GO:0051382 kinetochore assembly(GO:0051382)
0.0 1.9 GO:0036269 swimming behavior(GO:0036269)
0.0 1.2 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.0 0.6 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.4 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 2.1 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 1.6 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.7 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 2.2 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.3 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.9 GO:0018149 peptide cross-linking(GO:0018149)
0.0 3.1 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 1.9 GO:0034332 adherens junction organization(GO:0034332)
0.0 0.9 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 1.6 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.6 GO:1902656 calcium ion transmembrane import into cytosol(GO:0097553) calcium ion import into cytosol(GO:1902656)
0.0 0.2 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.8 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 1.0 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 11.3 GO:0098916 chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916) trans-synaptic signaling(GO:0099537)
0.0 1.6 GO:0014904 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 0.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.0 0.1 GO:0016246 RNA interference(GO:0016246)
0.0 0.2 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.4 GO:0099536 synaptic signaling(GO:0099536)
0.0 0.6 GO:0019229 regulation of vasoconstriction(GO:0019229)
0.0 2.8 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.3 GO:0031060 regulation of histone methylation(GO:0031060)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.4 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.4 GO:0006265 DNA topological change(GO:0006265)
0.0 1.4 GO:0007626 locomotory behavior(GO:0007626)
0.0 1.0 GO:0048484 enteric nervous system development(GO:0048484)
0.0 1.1 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.3 GO:0009566 single fertilization(GO:0007338) fertilization(GO:0009566)
0.0 2.6 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.4 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.1 GO:0048532 anatomical structure arrangement(GO:0048532)
0.0 1.8 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.4 GO:0007050 cell cycle arrest(GO:0007050)
0.0 2.8 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 1.0 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 1.5 GO:0016573 histone acetylation(GO:0016573)
0.0 1.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0015740 C4-dicarboxylate transport(GO:0015740)
0.0 0.8 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.9 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 2.1 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 0.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.4 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.2 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.8 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.1 GO:0032350 retinoic acid biosynthetic process(GO:0002138) regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of hormone metabolic process(GO:0032350) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 0.7 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.6 GO:0043648 dicarboxylic acid metabolic process(GO:0043648)
0.0 0.0 GO:0030858 positive regulation of epithelial cell differentiation(GO:0030858)
0.0 1.2 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.5 GO:0046513 ceramide biosynthetic process(GO:0046513)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.3 19.0 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
2.0 10.0 GO:0042584 chromaffin granule membrane(GO:0042584)
1.7 10.5 GO:0043083 synaptic cleft(GO:0043083)
1.3 12.6 GO:0098982 GABA-ergic synapse(GO:0098982)
0.9 2.8 GO:0033391 chromatoid body(GO:0033391)
0.8 5.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.8 5.0 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.8 8.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.7 4.4 GO:0005955 calcineurin complex(GO:0005955)
0.5 5.3 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.5 6.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.5 17.3 GO:0000421 autophagosome membrane(GO:0000421)
0.4 2.2 GO:0042583 chromaffin granule(GO:0042583)
0.4 2.9 GO:0071818 BAT3 complex(GO:0071818)
0.4 11.5 GO:0043186 P granule(GO:0043186)
0.3 4.1 GO:0044295 axonal growth cone(GO:0044295)
0.3 3.4 GO:0045171 intercellular bridge(GO:0045171)
0.3 4.8 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 1.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.3 1.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3 6.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 2.2 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.2 8.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 1.8 GO:0033010 paranodal junction(GO:0033010)
0.2 8.8 GO:0043204 perikaryon(GO:0043204)
0.2 3.1 GO:0070187 telosome(GO:0070187)
0.2 2.6 GO:0043209 myelin sheath(GO:0043209)
0.2 0.6 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.2 5.9 GO:0098978 glutamatergic synapse(GO:0098978)
0.2 4.7 GO:0032590 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.2 2.8 GO:0036038 MKS complex(GO:0036038)
0.2 8.6 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 42.5 GO:0030424 axon(GO:0030424)
0.1 2.4 GO:0031209 SCAR complex(GO:0031209)
0.1 1.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.6 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.8 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 6.9 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 2.1 GO:0042555 MCM complex(GO:0042555)
0.1 8.8 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1 0.3 GO:0097189 apoptotic body(GO:0097189)
0.1 3.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 2.0 GO:0030426 growth cone(GO:0030426)
0.1 0.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 2.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 1.9 GO:0030667 secretory granule membrane(GO:0030667)
0.1 1.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 3.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 0.6 GO:0034990 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 0.7 GO:0032021 NELF complex(GO:0032021)
0.1 4.8 GO:0014069 postsynaptic density(GO:0014069)
0.1 0.4 GO:0000801 central element(GO:0000801)
0.1 27.8 GO:0045202 synapse(GO:0045202)
0.1 3.2 GO:0016592 mediator complex(GO:0016592)
0.1 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.7 GO:0005903 brush border(GO:0005903)
0.0 5.4 GO:0016459 myosin complex(GO:0016459)
0.0 16.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 2.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.6 GO:0005682 U5 snRNP(GO:0005682)
0.0 2.9 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.8 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 2.6 GO:0036477 somatodendritic compartment(GO:0036477)
0.0 3.1 GO:0000786 nucleosome(GO:0000786)
0.0 2.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.3 GO:0030427 site of polarized growth(GO:0030427)
0.0 2.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 1.2 GO:0005871 kinesin complex(GO:0005871)
0.0 0.6 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.0 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.9 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.0 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 16.4 GO:0009374 biotin binding(GO:0009374)
2.7 13.5 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
2.3 9.4 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
1.7 5.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
1.4 23.2 GO:0032190 acrosin binding(GO:0032190)
1.2 5.9 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.8 4.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.8 2.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.8 5.4 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.7 4.4 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.7 12.6 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.6 6.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.6 4.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.5 1.8 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.4 2.6 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.4 17.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.4 2.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.4 5.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.4 3.6 GO:0008494 translation activator activity(GO:0008494)
0.4 5.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.4 12.6 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.4 7.2 GO:0015026 coreceptor activity(GO:0015026)
0.4 2.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.4 6.2 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.3 2.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 3.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.3 1.4 GO:0016521 pituitary adenylate cyclase activating polypeptide activity(GO:0016521)
0.3 5.1 GO:0005504 fatty acid binding(GO:0005504)
0.3 1.4 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.3 4.7 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237) benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.3 3.7 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.3 8.7 GO:0042577 lipid phosphatase activity(GO:0042577)
0.3 7.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.3 1.0 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.3 20.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.3 1.5 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.3 2.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.3 2.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.3 3.5 GO:0031628 opioid receptor binding(GO:0031628)
0.3 1.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.3 5.3 GO:0001671 ATPase activator activity(GO:0001671)
0.3 1.0 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 11.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 7.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 1.1 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.2 1.7 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.2 15.7 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.2 0.6 GO:0019777 Atg12 transferase activity(GO:0019777)
0.2 0.8 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.2 0.6 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.2 1.4 GO:0016530 metallochaperone activity(GO:0016530)
0.2 2.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 0.6 GO:0004945 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.2 1.2 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.1 2.8 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.9 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 2.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.5 GO:0031005 filamin binding(GO:0031005)
0.1 1.8 GO:0070628 proteasome binding(GO:0070628)
0.1 1.7 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 1.7 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.4 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.1 1.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 2.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 1.8 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 0.7 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 4.8 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 5.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 2.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 6.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.8 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.4 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 0.5 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.1 3.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 4.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 2.2 GO:0051787 misfolded protein binding(GO:0051787)
0.1 4.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 3.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 0.7 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 21.3 GO:0042802 identical protein binding(GO:0042802)
0.1 2.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 2.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 1.1 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.1 0.8 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.7 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 2.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 4.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.9 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 2.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 1.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 2.6 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 0.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 1.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.1 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.1 1.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 4.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.8 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 3.2 GO:0044325 ion channel binding(GO:0044325)
0.1 1.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.5 GO:0048039 ubiquinone binding(GO:0048039)
0.1 4.8 GO:0003724 RNA helicase activity(GO:0003724)
0.1 17.8 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 3.8 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.1 0.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.7 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.4 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 2.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.7 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.0 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 2.4 GO:0071949 FAD binding(GO:0071949)
0.0 4.0 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.9 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 1.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 2.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.8 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 1.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 1.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 1.2 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.8 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.6 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 6.7 GO:0003774 motor activity(GO:0003774)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 9.8 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.9 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.9 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 6.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 1.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 2.1 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 1.1 GO:0016247 channel regulator activity(GO:0016247)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 2.2 GO:0042393 histone binding(GO:0042393)
0.0 1.1 GO:0045296 cadherin binding(GO:0045296)
0.0 0.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 2.5 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 19.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 3.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.2 6.5 PID BMP PATHWAY BMP receptor signaling
0.1 3.7 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 0.4 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 2.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 1.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 2.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 3.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 0.6 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 2.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 1.0 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.0 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.8 PID SHP2 PATHWAY SHP2 signaling
0.0 0.4 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.6 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 PID BCR 5PATHWAY BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 19.0 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.4 1.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.3 4.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.3 3.1 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.3 4.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 4.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2 3.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.2 3.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 5.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 2.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 0.6 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 12.7 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 1.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 3.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 3.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 2.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 0.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 2.0 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.7 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.0 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 1.7 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway