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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for ybx1

Z-value: 1.09

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Transcription factors associated with ybx1

Gene Symbol Gene ID Gene Info
ybx1
ENSDARG00000004757 Y box binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ybx1dr11_v1_chr8_-_47152001_47152086-0.592.6e-10Click!

Activity profile of ybx1 motif

Sorted Z-values of ybx1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_+_44883805 30.48 ENSDART00000182805
si:ch73-361h17.1
si:ch73-361h17.1
chr22_+_38173960 19.76 ENSDART00000010537
cp
ceruloplasmin
chr25_-_4148719 16.47 ENSDART00000112880
ENSDART00000023278
fads2
fatty acid desaturase 2
chr18_+_62932 12.24 ENSDART00000052638
slc27a2a
solute carrier family 27 (fatty acid transporter), member 2a
chr13_+_2394534 10.20 ENSDART00000172535
ENSDART00000006990
elovl5
ELOVL fatty acid elongase 5
chr1_-_20928772 9.06 ENSDART00000078277
msmo1
methylsterol monooxygenase 1
chr10_+_6010570 7.96 ENSDART00000190025
ENSDART00000163680
hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr11_-_44543082 7.86 ENSDART00000099568
gpr137bb
G protein-coupled receptor 137Bb
chr10_+_10788811 7.78 ENSDART00000101077
ENSDART00000139143
ptgdsa
prostaglandin D2 synthase a
chr9_+_27411502 7.65 ENSDART00000143994
si:dkey-193n17.9
si:dkey-193n17.9
chr18_-_3166726 7.54 ENSDART00000165002
aqp11
aquaporin 11
chr13_+_2394264 7.44 ENSDART00000168595
elovl5
ELOVL fatty acid elongase 5
chr6_+_3710865 7.03 ENSDART00000170781
phospho2
phosphatase, orphan 2
chr6_-_34958274 6.74 ENSDART00000113097
hsd17b7
hydroxysteroid (17-beta) dehydrogenase 7
chr6_-_35446110 6.47 ENSDART00000058773
rgs16
regulator of G protein signaling 16
chr25_-_19433244 6.28 ENSDART00000154778
map1ab
microtubule-associated protein 1Ab
chr16_-_39477746 6.23 ENSDART00000102525
stt3b
STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
chr19_-_30562648 6.14 ENSDART00000171006
hpcal4
hippocalcin like 4
chr22_+_17205608 6.12 ENSDART00000181267
rab3b
RAB3B, member RAS oncogene family
chr4_+_11375894 6.08 ENSDART00000190471
ENSDART00000143963
pcloa
piccolo presynaptic cytomatrix protein a
chr16_-_39477509 5.81 ENSDART00000191330
stt3b
STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
chr24_+_17334682 5.75 ENSDART00000018868
pdia4
protein disulfide isomerase family A, member 4
chr1_-_18803919 5.46 ENSDART00000020970
pgm2
phosphoglucomutase 2
chr24_+_7708652 5.39 ENSDART00000066816
btr33
bloodthirsty-related gene family, member 33
chr15_+_43166511 5.38 ENSDART00000011737
flj13639
flj13639
chr16_-_44349845 5.36 ENSDART00000170932
rims2a
regulating synaptic membrane exocytosis 2a
chr17_+_23556764 5.25 ENSDART00000146787
pank1a
pantothenate kinase 1a
chr20_-_52939501 5.24 ENSDART00000166508
fdft1
farnesyl-diphosphate farnesyltransferase 1
chr20_-_7176809 5.19 ENSDART00000012247
ENSDART00000125019
dhcr24
24-dehydrocholesterol reductase
chr6_-_52156427 4.92 ENSDART00000082821
rims4
regulating synaptic membrane exocytosis 4
chr8_-_39884359 4.80 ENSDART00000131372
mlec
malectin
chr3_+_17951790 4.73 ENSDART00000164663
aclya
ATP citrate lyase a
chr3_+_59051503 4.67 ENSDART00000160767
rasd4
rasd family member 4
chr2_+_24868010 4.66 ENSDART00000078838
rab3aa
RAB3A, member RAS oncogene family, a
chr22_-_36875264 4.61 ENSDART00000137548
kng1
kininogen 1
chr10_+_7703251 4.58 ENSDART00000165134
ggcx
gamma-glutamyl carboxylase
chr15_-_19250543 4.42 ENSDART00000092705
ENSDART00000138895
igsf9ba
immunoglobulin superfamily, member 9Ba
chr18_+_27515640 4.31 ENSDART00000181593
tp53i11b
tumor protein p53 inducible protein 11b
chr4_-_28158335 4.12 ENSDART00000134605
gramd4a
GRAM domain containing 4a
chr23_+_45579497 4.07 ENSDART00000110381
egr4
early growth response 4
chr21_+_19070921 4.00 ENSDART00000029874
nkx6.1
NK6 homeobox 1
chr24_+_34606966 3.87 ENSDART00000105477
lrrtm2
leucine rich repeat transmembrane neuronal 2
chr15_-_20731297 3.84 ENSDART00000114464
tpst1
tyrosylprotein sulfotransferase 1
chr14_-_16476863 3.83 ENSDART00000089021
canx
calnexin
chr16_+_46695777 3.77 ENSDART00000169767
rab25b
RAB25, member RAS oncogene family b
chr7_+_1521834 3.74 ENSDART00000174007
si:cabz01102082.1
si:cabz01102082.1
chr21_+_244503 3.73 ENSDART00000162889
stard4
StAR-related lipid transfer (START) domain containing 4
chr23_+_19564392 3.71 ENSDART00000144746
atp6ap1lb
ATPase H+ transporting accessory protein 1 like b
chr4_-_5247335 3.71 ENSDART00000050221
atp6v1e1b
ATPase H+ transporting V1 subunit E1b
chr3_-_13147310 3.59 ENSDART00000160840
prkar1b
protein kinase, cAMP-dependent, regulatory, type I, beta
chr11_-_15297129 3.55 ENSDART00000167985
ENSDART00000163031
ENSDART00000165010
ENSDART00000171250
ENSDART00000010684
ENSDART00000191714
ENSDART00000191164
rpn2
ribophorin II
chr3_-_32541033 3.39 ENSDART00000151476
ENSDART00000055324
rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr9_-_1604601 3.31 ENSDART00000143130
agps
alkylglycerone phosphate synthase
chr15_-_3094516 3.26 ENSDART00000179719
slitrk5a
SLIT and NTRK-like family, member 5a
chr20_+_16743056 3.26 ENSDART00000050308
calm1b
calmodulin 1b
chr3_+_3810919 3.16 ENSDART00000056035
FQ311927.1

chr17_+_31221761 3.14 ENSDART00000155580
ccdc32
coiled-coil domain containing 32
chr18_+_7073130 3.13 ENSDART00000101216
ENSDART00000148947
si:dkey-88e18.2
si:dkey-88e18.2
chr2_+_24867534 3.12 ENSDART00000158050
rab3aa
RAB3A, member RAS oncogene family, a
chr24_-_39772045 3.11 ENSDART00000087441
GFOD1
si:ch211-276f18.2
chr21_+_3897680 3.10 ENSDART00000170653
dolpp1
dolichyldiphosphatase 1
chr25_+_25508495 3.08 ENSDART00000150719
phrf1
PHD and ring finger domains 1
chr24_+_24923166 3.08 ENSDART00000065288
pcyt1ba
phosphate cytidylyltransferase 1, choline, beta a
chr12_+_1469327 3.03 ENSDART00000059143
usp22
ubiquitin specific peptidase 22
chr21_+_5888641 3.03 ENSDART00000091331
prodha
proline dehydrogenase (oxidase) 1a
chr1_-_50527964 2.99 ENSDART00000024984
papss1
3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr2_+_37480669 2.83 ENSDART00000029801
sppl2
signal peptide peptidase-like 2
chr1_+_54737353 2.82 ENSDART00000130675
ENSDART00000162075
pi4k2a
phosphatidylinositol 4-kinase type 2 alpha
chr21_+_944715 2.76 ENSDART00000144766
nars
asparaginyl-tRNA synthetase
chr1_+_24076243 2.76 ENSDART00000014608
mab21l2
mab-21-like 2
chr11_-_30352333 2.71 ENSDART00000030794
tmem169a
transmembrane protein 169a
chr9_+_2452672 2.65 ENSDART00000193993
chn1
chimerin 1
chr8_+_54081819 2.56 ENSDART00000005857
ENSDART00000161795
prickle2a
prickle homolog 2a
chr21_-_26406244 2.56 ENSDART00000137312
ENSDART00000077200
eif4ebp3
eukaryotic translation initiation factor 4E binding protein 3
chr12_+_46960579 2.54 ENSDART00000149032
oat
ornithine aminotransferase
chr20_-_3403033 2.41 ENSDART00000092264
rev3l
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr21_+_34981263 2.41 ENSDART00000132711
rbm11
RNA binding motif protein 11
chr5_+_20030414 2.39 ENSDART00000181430
ENSDART00000047841
ENSDART00000182813
sgsm1a
small G protein signaling modulator 1a
chr6_-_25952848 2.37 ENSDART00000076997
ENSDART00000148748
lmo4b
LIM domain only 4b
chr14_-_12020653 2.32 ENSDART00000106654
znf711
zinc finger protein 711
chr23_+_6795531 2.31 ENSDART00000092131
si:ch211-117c9.5
si:ch211-117c9.5
chr23_+_2778813 2.30 ENSDART00000142621
top1
DNA topoisomerase I
chr21_-_12119711 2.29 ENSDART00000131538
celf4
CUGBP, Elav-like family member 4
chr3_-_58543658 2.29 ENSDART00000042386
unm_sa1261
un-named sa1261
chr1_+_43686251 2.29 ENSDART00000074604
ENSDART00000137791
cisd2
CDGSH iron sulfur domain 2
chr4_+_4079418 2.23 ENSDART00000028016
waslb
Wiskott-Aldrich syndrome-like b
chr11_-_42554290 2.23 ENSDART00000130573
atp6ap1la
ATPase H+ transporting accessory protein 1 like a
chr5_-_16983336 2.22 ENSDART00000038740
galnt9
polypeptide N-acetylgalactosaminyltransferase 9
chr15_-_19677511 2.16 ENSDART00000043743
si:dkey-4p15.3
si:dkey-4p15.3
chr16_-_32672883 2.15 ENSDART00000124515
ENSDART00000190920
ENSDART00000188776
pnisr
PNN-interacting serine/arginine-rich protein
chr2_-_4797512 2.13 ENSDART00000160765
tnk2b
tyrosine kinase, non-receptor, 2b
chr19_+_42806812 2.13 ENSDART00000108775
ENSDART00000151653
ubp1
upstream binding protein 1
chr16_-_12095144 2.12 ENSDART00000145106
pex5
peroxisomal biogenesis factor 5
chr1_+_51386649 2.09 ENSDART00000152289
atg4da
autophagy related 4D, cysteine peptidase a
chr11_-_18604317 2.09 ENSDART00000182081
zmynd8
zinc finger, MYND-type containing 8
chr11_-_15296805 2.06 ENSDART00000124968
rpn2
ribophorin II
chr11_-_18604542 2.05 ENSDART00000171183
zmynd8
zinc finger, MYND-type containing 8
chr15_+_41836104 1.99 ENSDART00000137434
pxylp1
2-phosphoxylose phosphatase 1
chr23_-_10786400 1.96 ENSDART00000055038
rybpa
RING1 and YY1 binding protein a
chr5_+_26138313 1.96 ENSDART00000010041
dhfr
dihydrofolate reductase
chr22_-_12693833 1.92 ENSDART00000129768
ENSDART00000044574
adarb1a
adenosine deaminase, RNA-specific, B1a
chr8_-_1266181 1.88 ENSDART00000148654
ENSDART00000149924
cdc14b
cell division cycle 14B
chr3_-_21062706 1.88 ENSDART00000155605
ENSDART00000153686
ENSDART00000157168
ENSDART00000156614
ENSDART00000155743
ENSDART00000156275
fam57ba
family with sequence similarity 57, member Ba
chr20_-_53366137 1.86 ENSDART00000146001
wasf1
WAS protein family, member 1
chr5_-_2721686 1.85 ENSDART00000169404
hspa5
heat shock protein 5
chr12_+_1469090 1.84 ENSDART00000183637
usp22
ubiquitin specific peptidase 22
chr18_+_40364732 1.80 ENSDART00000123661
ENSDART00000130847
sema6dl
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr18_+_22606259 1.78 ENSDART00000128965
bcar1
breast cancer anti-estrogen resistance 1
chr1_+_25801648 1.77 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr22_-_16180467 1.75 ENSDART00000171331
ENSDART00000185607
vcam1b
vascular cell adhesion molecule 1b
chr4_-_9196291 1.72 ENSDART00000153963
hcfc2
host cell factor C2
chr11_+_14321113 1.71 ENSDART00000039822
ENSDART00000137347
ENSDART00000132997
ptbp1b
polypyrimidine tract binding protein 1b
chr3_-_37585863 1.70 ENSDART00000149762
arf2a
ADP-ribosylation factor 2a
chr12_+_38807604 1.68 ENSDART00000155563
abca5
ATP-binding cassette, sub-family A (ABC1), member 5
chr9_+_22677503 1.67 ENSDART00000131429
ENSDART00000080005
ENSDART00000101756
ENSDART00000138148
itgb5
integrin, beta 5
chr19_+_14109348 1.67 ENSDART00000159015
zgc:175136
zgc:175136
chr13_+_8892784 1.65 ENSDART00000075054
ENSDART00000143705
thada
thyroid adenoma associated
chr18_-_2549198 1.64 ENSDART00000186516
CABZ01070631.1

chr6_+_53349966 1.64 ENSDART00000167079
si:ch211-161c3.5
si:ch211-161c3.5
chr1_-_20271138 1.62 ENSDART00000185931
ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr4_+_29967255 1.59 ENSDART00000150383
znf1128
zinc finger protein 1128
chr13_-_30700460 1.56 ENSDART00000139073
rassf4
Ras association (RalGDS/AF-6) domain family member 4
chr2_+_29249204 1.55 ENSDART00000168957
cdh18a
cadherin 18, type 2a
chr17_-_43287290 1.54 ENSDART00000156885
EML5
si:dkey-1f12.3
chr19_+_770300 1.49 ENSDART00000062518
gstr
glutathione S-transferase rho
chr1_-_9644630 1.48 ENSDART00000123725
ENSDART00000161164
ugt5b3
UDP glucuronosyltransferase 5 family, polypeptide B3
chr12_+_40905427 1.39 ENSDART00000170526
ENSDART00000185771
ENSDART00000193945
CDH18
cadherin 18
chr19_-_6134802 1.39 ENSDART00000140051
cica
capicua transcriptional repressor a
chr7_-_29115772 1.37 ENSDART00000076386
fbxl8
F-box and leucine-rich repeat protein 8
chr3_-_61218272 1.36 ENSDART00000133091
ENSDART00000055068
pvalb5
parvalbumin 5
chr19_-_26769867 1.36 ENSDART00000043776
ENSDART00000159489
ENSDART00000138675
prrc2a
proline-rich coiled-coil 2A
chr3_+_62353650 1.35 ENSDART00000112428
iqck
IQ motif containing K
chr25_-_6261693 1.34 ENSDART00000135808
ireb2
iron-responsive element binding protein 2
chr6_-_51541488 1.32 ENSDART00000156336
si:dkey-6e2.2
si:dkey-6e2.2
chr18_+_17600570 1.32 ENSDART00000175258
ENSDART00000151850
ENSDART00000151934
herpud1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr10_-_2713228 1.28 ENSDART00000123754
ENSDART00000126236
mier3a
mesoderm induction early response 1, family member 3 a
chr18_+_44795711 1.27 ENSDART00000110229
ENSDART00000188262
ENSDART00000139526
fam118b
family with sequence similarity 118, member B
chr8_+_53269657 1.27 ENSDART00000184212
gnb1a
guanine nucleotide binding protein (G protein), beta polypeptide 1a
chr23_+_36616717 1.26 ENSDART00000042701
ENSDART00000192980
pip4k2ca
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma a
chr12_-_35885349 1.25 ENSDART00000085662
cep131
centrosomal protein 131
chr9_-_12594759 1.25 ENSDART00000021266
tra2b
transformer 2 beta homolog
chr7_-_56835543 1.24 ENSDART00000010322
senp8
SUMO/sentrin peptidase family member, NEDD8 specific
chr3_+_16664212 1.23 ENSDART00000013816
zgc:55558
zgc:55558
chr20_-_40487208 1.21 ENSDART00000075070
ENSDART00000142029
hsf2
heat shock transcription factor 2
chr5_+_26686279 1.20 ENSDART00000193543
tango2
transport and golgi organization 2 homolog (Drosophila)
chr12_-_48671612 1.20 ENSDART00000007202
zgc:92749
zgc:92749
chr19_-_26770083 1.18 ENSDART00000193811
ENSDART00000174455
prrc2a
proline-rich coiled-coil 2A
chr1_+_6817292 1.18 ENSDART00000145822
ENSDART00000092118
erbb4a
erb-b2 receptor tyrosine kinase 4a
chr20_-_49889111 1.15 ENSDART00000058858
kif13bb
kinesin family member 13Bb
chr17_-_43286903 1.14 ENSDART00000176637
EML5
si:dkey-1f12.3
chr1_+_30723677 1.13 ENSDART00000177900
bora
bora, aurora kinase A activator
chr23_-_41651759 1.13 ENSDART00000146808
si:ch73-184c24.1
si:ch73-184c24.1
chr11_+_18612166 1.13 ENSDART00000162694
ncoa3
nuclear receptor coactivator 3
chr10_+_36026576 1.12 ENSDART00000193786
hmgb1a
high mobility group box 1a
chr2_+_9946121 1.12 ENSDART00000100696
tsen15
TSEN15 tRNA splicing endonuclease subunit
chr12_-_33582382 1.09 ENSDART00000009794
ENSDART00000136617
tdrkh
tudor and KH domain containing
chr25_-_17918810 1.09 ENSDART00000023959
arntl1a
aryl hydrocarbon receptor nuclear translocator-like 1a
chr20_+_18703108 1.09 ENSDART00000181188
eif5
eukaryotic translation initiation factor 5
chr7_+_39360797 1.09 ENSDART00000173481
acp2
acid phosphatase 2, lysosomal
chr3_+_62317990 1.08 ENSDART00000058719
znf1124
zinc finger protein 1124
chr12_-_10674606 1.08 ENSDART00000157919
med24
mediator complex subunit 24
chr16_+_4838808 1.07 ENSDART00000179363
ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr3_+_35498119 1.04 ENSDART00000178963
tnrc6a
trinucleotide repeat containing 6a
chr11_+_26375979 1.03 ENSDART00000087652
ENSDART00000171748
ENSDART00000103513
ENSDART00000165931
ENSDART00000170043
cpne1
rbm12
copine I
RNA binding motif protein 12
chr9_+_45227028 1.02 ENSDART00000185579
adarb1b
adenosine deaminase, RNA-specific, B1b
chr25_+_4541211 1.02 ENSDART00000129978
pnpla2
patatin-like phospholipase domain containing 2
chr19_-_31686252 0.99 ENSDART00000131721
ripor2
RHO family interacting cell polarization regulator 2
chr16_-_52646789 0.99 ENSDART00000035761
ubr5
ubiquitin protein ligase E3 component n-recognin 5
chr8_-_44015210 0.97 ENSDART00000186879
ENSDART00000188965
ENSDART00000001313
ENSDART00000188902
ENSDART00000185935
ENSDART00000147869
rimbp2
rimbp2
RIMS binding protein 2
RIMS binding protein 2
chr23_+_6795709 0.96 ENSDART00000149136
si:ch211-117c9.5
si:ch211-117c9.5
chr13_-_856701 0.96 ENSDART00000140423
TMEM14A
zgc:163080
chr21_-_5007109 0.96 ENSDART00000187042
ENSDART00000097796
ENSDART00000146766
rnf165a
ring finger protein 165a
chr7_+_34794829 0.95 ENSDART00000009698
ENSDART00000075089
ENSDART00000173456
esrp2
epithelial splicing regulatory protein 2
chr1_+_1599979 0.95 ENSDART00000097626
urp2
urotensin II-related peptide
chr10_-_7858553 0.94 ENSDART00000182010
inpp5ja
inositol polyphosphate-5-phosphatase Ja
chr24_-_24271629 0.94 ENSDART00000135060
rps6ka3b
ribosomal protein S6 kinase, polypeptide 3b
chr13_-_856525 0.93 ENSDART00000143356
TMEM14A
zgc:163080
chr10_+_44903676 0.92 ENSDART00000158553
zgc:114173
zgc:114173
chr11_-_45152702 0.92 ENSDART00000168066
afmid
arylformamidase
chr15_+_26941063 0.92 ENSDART00000149957
bcas3
breast carcinoma amplified sequence 3
chr7_-_31794476 0.90 ENSDART00000142385
nap1l4b
nucleosome assembly protein 1-like 4b
chr22_+_1285182 0.90 ENSDART00000171750
si:ch73-138e16.3
si:ch73-138e16.3
chr6_+_2951645 0.90 ENSDART00000183181
ENSDART00000181271
ptprfa
protein tyrosine phosphatase, receptor type, f, a
chr25_+_10458990 0.88 ENSDART00000130354
ENSDART00000044738
ric8a
RIC8 guanine nucleotide exchange factor A
chr12_+_25432627 0.87 ENSDART00000011662
ppm1bb
protein phosphatase, Mg2+/Mn2+ dependent, 1Bb
chr3_-_1146497 0.84 ENSDART00000149061
si:ch73-211l13.2
si:ch73-211l13.2
chr3_-_5964557 0.83 ENSDART00000184738
BX284638.1

chr18_-_18942098 0.80 ENSDART00000100458
si:dkey-73n10.1
si:dkey-73n10.1
chr7_+_57088920 0.79 ENSDART00000024076
scamp2l
secretory carrier membrane protein 2, like
chr16_+_49647402 0.79 ENSDART00000015694
ENSDART00000132547
rab5ab
RAB5A, member RAS oncogene family, b
chr6_-_6448519 0.75 ENSDART00000180157
ENSDART00000191112
si:ch211-194e18.2
si:ch211-194e18.2
chr20_+_37866171 0.74 ENSDART00000153190
vash2
vasohibin 2
chr17_+_35097024 0.74 ENSDART00000026152
asap2a
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2a
chr6_+_37752781 0.73 ENSDART00000154364
herc2
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr25_-_35542739 0.72 ENSDART00000097651
si:ch211-87j1.4
si:ch211-87j1.4
chr3_+_17878466 0.72 ENSDART00000180218
dnajc7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr19_-_27334394 0.72 ENSDART00000052359
gtf2h4
general transcription factor IIH, polypeptide 4
chr1_-_30723241 0.71 ENSDART00000152175
ENSDART00000152150
MZT1
si:dkey-15d12.2
chr3_+_17878124 0.70 ENSDART00000166430
ENSDART00000163421
ENSDART00000121473
dnajc7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr7_-_69636502 0.69 ENSDART00000126739
tspan5a
tetraspanin 5a

Network of associatons between targets according to the STRING database.

First level regulatory network of ybx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.0 GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
2.6 7.9 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
2.6 7.8 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
1.2 3.7 GO:0071470 cellular response to osmotic stress(GO:0071470)
1.1 3.3 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
1.0 5.2 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
1.0 4.1 GO:0034164 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
1.0 3.0 GO:0050428 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.9 19.8 GO:0006825 copper ion transport(GO:0006825)
0.9 3.7 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.9 18.8 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.8 4.6 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.7 7.4 GO:0050819 negative regulation of coagulation(GO:0050819)
0.7 12.0 GO:0043687 protein N-linked glycosylation via asparagine(GO:0018279) post-translational protein modification(GO:0043687)
0.7 2.7 GO:0021557 oculomotor nerve development(GO:0021557)
0.6 6.1 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.6 3.0 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.6 2.3 GO:0010259 multicellular organism aging(GO:0010259)
0.5 2.0 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.5 3.8 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.5 10.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.4 1.8 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.4 1.3 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.4 16.5 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.4 3.7 GO:0060036 notochord cell vacuolation(GO:0060036)
0.4 2.0 GO:0090527 actin filament reorganization(GO:0090527)
0.4 15.8 GO:0016126 sterol biosynthetic process(GO:0016126)
0.4 2.0 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.3 4.9 GO:0034033 nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.3 4.0 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.3 1.0 GO:1990868 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.3 2.5 GO:0055129 arginine catabolic process(GO:0006527) proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.3 2.8 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.3 4.1 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.3 2.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.3 0.8 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.3 2.6 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.3 1.0 GO:0010898 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.3 1.3 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.2 2.9 GO:0006382 adenosine to inosine editing(GO:0006382)
0.2 6.3 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.2 4.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 3.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.2 2.1 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.2 2.1 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.2 1.9 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.2 1.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735) negative regulation of intracellular protein transport(GO:0090317)
0.2 2.8 GO:0007032 endosome organization(GO:0007032)
0.2 1.0 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.2 6.1 GO:0072350 citrate metabolic process(GO:0006101) tricarboxylic acid metabolic process(GO:0072350)
0.2 1.3 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 5.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 1.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 2.4 GO:0006265 DNA topological change(GO:0006265)
0.1 0.7 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 1.8 GO:0042026 protein refolding(GO:0042026)
0.1 0.9 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 0.9 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.1 1.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 1.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 8.7 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.1 1.5 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 1.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 0.9 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 5.9 GO:0030641 regulation of cellular pH(GO:0030641)
0.1 2.9 GO:0009648 photoperiodism(GO:0009648)
0.1 10.1 GO:0006457 protein folding(GO:0006457)
0.1 1.1 GO:0009409 response to cold(GO:0009409)
0.1 1.0 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 1.6 GO:1990798 pancreas regeneration(GO:1990798)
0.1 0.3 GO:0060760 positive regulation of cytokine-mediated signaling pathway(GO:0001961) positive regulation of response to cytokine stimulus(GO:0060760)
0.1 1.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 1.7 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 5.2 GO:0008202 steroid metabolic process(GO:0008202)
0.0 1.1 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.7 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 4.7 GO:0031101 fin regeneration(GO:0031101)
0.0 1.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 2.8 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.9 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 4.9 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.3 GO:0051299 mitotic centrosome separation(GO:0007100) centrosome separation(GO:0051299)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.4 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 5.2 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 4.3 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.5 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 1.8 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.5 GO:0043489 RNA stabilization(GO:0043489)
0.0 1.6 GO:0009306 protein secretion(GO:0009306)
0.0 1.8 GO:0006006 glucose metabolic process(GO:0006006)
0.0 0.3 GO:0060324 face development(GO:0060324)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.9 GO:0008217 regulation of blood pressure(GO:0008217)
0.0 3.1 GO:0006887 exocytosis(GO:0006887)
0.0 0.1 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.9 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.7 2.8 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.6 1.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.6 6.1 GO:0098982 GABA-ergic synapse(GO:0098982)
0.5 10.3 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.4 5.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.4 3.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 1.0 GO:0060171 stereocilium membrane(GO:0060171)
0.2 0.8 GO:0098842 postsynaptic early endosome(GO:0098842)
0.2 2.4 GO:0042575 DNA polymerase complex(GO:0042575)
0.2 3.7 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.2 21.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 1.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.9 GO:0031209 SCAR complex(GO:0031209)
0.1 2.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 1.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 5.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.7 GO:0000439 core TFIIH complex(GO:0000439)
0.1 1.3 GO:0015030 Cajal body(GO:0015030)
0.1 1.7 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.5 GO:0071818 BAT3 complex(GO:0071818)
0.1 0.5 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 1.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 3.9 GO:0048786 presynaptic active zone(GO:0048786)
0.1 10.5 GO:0008021 synaptic vesicle(GO:0008021)
0.1 40.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 3.8 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 7.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 1.2 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.1 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 3.8 GO:0055037 recycling endosome(GO:0055037)
0.0 6.3 GO:0043025 neuronal cell body(GO:0043025)
0.0 3.3 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.7 GO:0008305 integrin complex(GO:0008305)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 3.8 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.0 1.9 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:0005685 U1 snRNP(GO:0005685)
0.0 8.2 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 1.8 GO:0005925 focal adhesion(GO:0005925)
0.0 1.4 GO:0005871 kinesin complex(GO:0005871)
0.0 0.9 GO:0001726 ruffle(GO:0001726)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 18.0 GO:0005615 extracellular space(GO:0005615)
0.0 1.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.5 GO:0005681 spliceosomal complex(GO:0005681)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 12.0 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
2.7 8.0 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
1.7 5.2 GO:0004311 farnesyltranstransferase activity(GO:0004311)
1.3 19.8 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
1.3 9.1 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
1.1 4.6 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
1.0 3.0 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.9 4.7 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.9 18.8 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.9 5.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.8 12.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.8 3.0 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.6 3.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.5 3.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.5 3.8 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.5 5.5 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.4 1.3 GO:0003994 aconitate hydratase activity(GO:0003994)
0.4 5.7 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.4 2.8 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.4 2.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.4 2.8 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.3 6.1 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.3 3.7 GO:0008556 potassium-transporting ATPase activity(GO:0008556)
0.3 1.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.3 0.9 GO:0004061 arylformamidase activity(GO:0004061)
0.3 1.5 GO:0043295 glutathione binding(GO:0043295)
0.3 2.9 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.3 2.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 1.0 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 6.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 1.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 1.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 11.6 GO:0044325 ion channel binding(GO:0044325)
0.2 1.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 2.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.2 8.5 GO:0071949 FAD binding(GO:0071949)
0.2 5.9 GO:0019003 GDP binding(GO:0019003)
0.1 3.7 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 1.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 1.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 1.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.9 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 4.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 1.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 2.5 GO:0008483 transaminase activity(GO:0008483)
0.1 1.3 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 0.9 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 2.0 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 3.7 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.5 GO:0030619 U1 snRNA binding(GO:0030619)
0.1 2.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 1.1 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 6.7 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 18.9 GO:0003924 GTPase activity(GO:0003924)
0.0 3.8 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 2.4 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 4.9 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 2.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 1.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 1.7 GO:0005178 integrin binding(GO:0005178)
0.0 11.8 GO:0016791 phosphatase activity(GO:0016791)
0.0 7.0 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 7.2 GO:0008017 microtubule binding(GO:0008017)
0.0 2.0 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 1.7 GO:0043492 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 3.0 GO:0000989 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 7.5 GO:0022803 channel activity(GO:0015267) passive transmembrane transporter activity(GO:0022803)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 19.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.3 4.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 5.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 8.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 1.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 4.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 2.8 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 1.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.1 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 34.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
1.4 34.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
1.1 19.8 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.7 3.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.5 4.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.4 8.6 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.4 5.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.4 4.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 2.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.3 3.6 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.3 2.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 1.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 3.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.2 3.1 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 2.8 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.8 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 1.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.7 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 1.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 5.6 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.1 0.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.0 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.7 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 2.0 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 1.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.0 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs