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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for zbtb14

Z-value: 3.24

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Transcription factors associated with zbtb14

Gene Symbol Gene ID Gene Info
zbtb14
ENSDARG00000098273 zinc finger and BTB domain containing 14

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zbtb14dr11_v1_chr24_+_41989108_419891080.431.4e-05Click!

Activity profile of zbtb14 motif

Sorted Z-values of zbtb14 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_25649626 83.69 ENSDART00000146947
tac1
tachykinin 1
chr16_-_43026273 55.56 ENSDART00000156820
ENSDART00000189080
si:dkey-7j14.5
si:dkey-7j14.5
chr23_+_44732863 51.37 ENSDART00000160044
ENSDART00000172268
atp1b2a
ATPase Na+/K+ transporting subunit beta 2a
chr16_-_43025885 45.98 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
si:dkey-7j14.5
chr1_-_56223913 44.95 ENSDART00000019573
zgc:65894
zgc:65894
chr21_+_11468934 43.39 ENSDART00000126045
ENSDART00000129744
ENSDART00000102368
grin1a
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr4_+_5741733 42.50 ENSDART00000110243
pou3f2a
POU class 3 homeobox 2a
chr3_-_21280373 42.00 ENSDART00000003939
syngr1a
synaptogyrin 1a
chr22_-_21150845 41.08 ENSDART00000027345
tmem59l
transmembrane protein 59-like
chr25_+_21324588 40.65 ENSDART00000151842
lrrn3a
leucine rich repeat neuronal 3a
chr1_-_21409877 40.41 ENSDART00000102782
gria2a
glutamate receptor, ionotropic, AMPA 2a
chr19_-_5254699 39.11 ENSDART00000081951
stx1b
syntaxin 1B
chr8_+_26868105 37.68 ENSDART00000005337
rimkla
ribosomal modification protein rimK-like family member A
chr2_+_42724404 36.93 ENSDART00000075392
basp1
brain abundant, membrane attached signal protein 1
chr24_+_32176155 36.64 ENSDART00000003745
vim
vimentin
chr11_+_7324704 36.25 ENSDART00000031937
diras1a
DIRAS family, GTP-binding RAS-like 1a
chr25_+_14165447 35.21 ENSDART00000145387
shank2
SH3 and multiple ankyrin repeat domains 2
chr4_-_5764255 34.92 ENSDART00000113864
faxca
failed axon connections homolog a
chr24_+_14713776 34.60 ENSDART00000134475
gdap1
ganglioside induced differentiation associated protein 1
chr25_-_22639133 33.83 ENSDART00000073583
islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr20_-_35246150 33.77 ENSDART00000090549
fzd3a
frizzled class receptor 3a
chr14_-_2163454 33.48 ENSDART00000160123
ENSDART00000169653
pcdh2ab9
pcdh2ac
protocadherin 2 alpha b 9
protocadherin 2 alpha c
chr10_-_15405564 33.44 ENSDART00000020665
sgtb
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr16_+_45456066 31.79 ENSDART00000093365
syngap1b
synaptic Ras GTPase activating protein 1b
chr18_-_5692292 30.88 ENSDART00000121503
cplx3b
complexin 3b
chr5_-_22952156 30.67 ENSDART00000111146
si:ch211-26b3.4
si:ch211-26b3.4
chr20_-_40451115 30.61 ENSDART00000075092
pkib
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr1_-_20911297 30.57 ENSDART00000078271
cpe
carboxypeptidase E
chr7_+_32722227 30.36 ENSDART00000126565
si:ch211-150g13.3
si:ch211-150g13.3
chr16_-_26074529 30.20 ENSDART00000148653
ENSDART00000148923
tmem145
transmembrane protein 145
chr21_+_11468642 29.99 ENSDART00000041869
grin1a
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr8_+_48603398 29.81 ENSDART00000074900
zgc:195023
zgc:195023
chr19_-_13733870 29.39 ENSDART00000177773
epb41a
erythrocyte membrane protein band 4.1a
chr14_-_34276574 29.26 ENSDART00000021437
gria1a
glutamate receptor, ionotropic, AMPA 1a
chr2_+_26179096 28.61 ENSDART00000024662
plppr3a
phospholipid phosphatase related 3a
chr14_-_25577094 28.00 ENSDART00000163669
cplx2
complexin 2
chr13_+_30054996 27.92 ENSDART00000110061
ENSDART00000186045
spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr11_+_15931188 27.61 ENSDART00000165768
ENSDART00000081098
draxin
dorsal inhibitory axon guidance protein
chr22_-_12160283 26.37 ENSDART00000146785
ENSDART00000128176
tmem163b
transmembrane protein 163b
chr10_+_466926 26.36 ENSDART00000145220
arvcfa
ARVCF, delta catenin family member a
chr14_-_9199968 25.79 ENSDART00000146113
arhgef9b
Cdc42 guanine nucleotide exchange factor (GEF) 9b
chr13_-_27767330 25.70 ENSDART00000131631
ENSDART00000112553
ENSDART00000189911
rims1a
regulating synaptic membrane exocytosis 1a
chr1_+_53321878 25.54 ENSDART00000143909
tbc1d9
TBC1 domain family, member 9 (with GRAM domain)
chr24_+_5840748 25.17 ENSDART00000139191
trpc1
transient receptor potential cation channel, subfamily C, member 1
chr14_+_11103718 25.06 ENSDART00000161311
nexmifb
neurite extension and migration factor b
chr22_-_372723 24.80 ENSDART00000112895
FNDC10
si:zfos-1324h11.5
chr1_-_50859053 24.76 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr7_+_48288762 23.81 ENSDART00000083569
oaz2b
ornithine decarboxylase antizyme 2b
chr23_-_39849155 23.21 ENSDART00000115330
ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr7_+_39624728 22.55 ENSDART00000173847
ENSDART00000173845
ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr5_+_63668735 22.46 ENSDART00000134261
ENSDART00000097330
dnm1b
dynamin 1b
chr6_-_13308813 22.31 ENSDART00000065372
kcnj3b
potassium inwardly-rectifying channel, subfamily J, member 3b
chr1_-_38709551 22.26 ENSDART00000128794
gpm6ab
glycoprotein M6Ab
chr3_-_36115339 22.17 ENSDART00000187406
ENSDART00000123505
ENSDART00000151775
rab11fip4a
RAB11 family interacting protein 4 (class II) a
chr1_-_8428736 22.10 ENSDART00000138435
ENSDART00000121823
syngr3b
synaptogyrin 3b
chr2_-_24462277 21.88 ENSDART00000033922
kcnn1a
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1a
chr12_+_21299338 21.71 ENSDART00000074540
ENSDART00000133188
ca10a
carbonic anhydrase Xa
chr6_-_11780070 21.54 ENSDART00000151195
march7
membrane-associated ring finger (C3HC4) 7
chr12_+_21298317 21.33 ENSDART00000178562
ca10a
carbonic anhydrase Xa
chr2_-_44720551 21.15 ENSDART00000146380
map6d1
MAP6 domain containing 1
chr7_-_49594995 21.14 ENSDART00000174161
ENSDART00000109147
brsk2b
BR serine/threonine kinase 2b
chr13_+_30055171 20.97 ENSDART00000143581
ENSDART00000132027
spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr25_+_4837915 20.71 ENSDART00000168016
gnb5a
guanine nucleotide binding protein (G protein), beta 5a
chr21_+_15870752 20.66 ENSDART00000122015
fam169ab
family with sequence similarity 169, member Ab
chr24_+_5840258 20.57 ENSDART00000087034
trpc1
transient receptor potential cation channel, subfamily C, member 1
chr13_+_35746440 20.50 ENSDART00000187859
gpr75
G protein-coupled receptor 75
chr3_-_36944749 19.44 ENSDART00000154501
cntnap1
contactin associated protein 1
chr2_-_44398611 19.43 ENSDART00000146192
pip4p1a
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1a
chr16_+_32559821 19.41 ENSDART00000093250
pou3f2b
POU class 3 homeobox 2b
chr24_+_4977862 19.34 ENSDART00000114537
zic4
zic family member 4
chr25_-_3979583 19.29 ENSDART00000124749
myrf
myelin regulatory factor
chr14_-_4682114 19.26 ENSDART00000014454
gabra4
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4
chr5_-_21030934 19.20 ENSDART00000133461
ENSDART00000098667
camk2b1
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
chr17_+_51764310 18.71 ENSDART00000157171
si:ch211-168d23.3
si:ch211-168d23.3
chr5_-_31712399 18.56 ENSDART00000141328
pip5kl1
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr10_+_23060391 18.53 ENSDART00000079711
slc25a1a
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1a
chr13_+_27073901 18.44 ENSDART00000146227
slc24a3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr25_-_12203952 18.19 ENSDART00000158204
ENSDART00000091727
ntrk3a
neurotrophic tyrosine kinase, receptor, type 3a
chr13_-_31470439 18.07 ENSDART00000076574
rtn1a
reticulon 1a
chr1_-_22834824 17.94 ENSDART00000043556
ldb2b
LIM domain binding 2b
chr10_-_13772847 17.85 ENSDART00000145103
ENSDART00000184491
cntfr
ciliary neurotrophic factor receptor
chr17_+_50127648 17.51 ENSDART00000156460
galnt16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr25_-_20381271 17.20 ENSDART00000142665
kctd15a
potassium channel tetramerization domain containing 15a
chr21_+_39423974 17.15 ENSDART00000031470
pafah1b1b
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b
chr21_-_25573064 17.06 ENSDART00000134310
CR388166.1

chr7_+_14632157 17.04 ENSDART00000161264
ntrk3b
neurotrophic tyrosine kinase, receptor, type 3b
chr24_+_41931585 16.95 ENSDART00000130310
epb41l3a
erythrocyte membrane protein band 4.1-like 3a
chr20_+_25350435 16.88 ENSDART00000063034
fam228a
family with sequence similarity 228, member A
chr1_+_9004719 16.38 ENSDART00000006211
ENSDART00000137211
prkcba
protein kinase C, beta a
chr12_-_7607114 16.36 ENSDART00000158095
slc16a9b
solute carrier family 16, member 9b
chr20_+_50852356 16.32 ENSDART00000167517
ENSDART00000168396
gphnb
gephyrin b
chr4_-_9810999 16.28 ENSDART00000146858
si:dkeyp-27e10.3
si:dkeyp-27e10.3
chr3_+_32789605 16.19 ENSDART00000171895
tbc1d10b
TBC1 domain family, member 10b
chr4_-_797831 16.16 ENSDART00000158970
ENSDART00000170012
mapre3b
microtubule-associated protein, RP/EB family, member 3b
chr10_-_17170086 16.11 ENSDART00000020122
ywhah
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr5_-_34185497 16.04 ENSDART00000146321
fibcd1
fibrinogen C domain containing 1
chr8_+_47897734 15.95 ENSDART00000140266
mfn2
mitofusin 2
chr20_-_9963713 15.89 ENSDART00000104234
gjd2b
gap junction protein delta 2b
chr24_+_4978055 15.83 ENSDART00000045813
zic4
zic family member 4
chr19_+_1184878 15.78 ENSDART00000163539
scrt1a
scratch family zinc finger 1a
chr18_+_42970208 15.71 ENSDART00000084454
nectin1b
nectin cell adhesion molecule 1b
chr23_+_41800052 15.54 ENSDART00000141484
pdyn
prodynorphin
chr16_+_52771199 15.52 ENSDART00000111383
baalca
brain and acute leukemia, cytoplasmic a
chr20_+_18209895 15.50 ENSDART00000111063
kctd1
potassium channel tetramerization domain containing 1
chr6_+_4539953 15.49 ENSDART00000025031
pou4f1
POU class 4 homeobox 1
chr24_-_6501211 15.47 ENSDART00000186241
ENSDART00000109040
ENSDART00000136154
gpr158a
G protein-coupled receptor 158a
chr22_-_22416337 15.40 ENSDART00000142947
ENSDART00000089569
camsap2a
calmodulin regulated spectrin-associated protein family, member 2a
chr13_-_29421331 15.33 ENSDART00000150228
chata
choline O-acetyltransferase a
chr20_+_474288 15.31 ENSDART00000026794
nt5dc1
5'-nucleotidase domain containing 1
chr7_+_73332486 15.16 ENSDART00000174119
ENSDART00000092051
ENSDART00000192388
CABZ01081780.1

chr4_-_12007404 15.15 ENSDART00000092250
btbd11a
BTB (POZ) domain containing 11a
chr22_-_29922872 15.06 ENSDART00000020249
dusp5
dual specificity phosphatase 5
chr12_+_12112384 14.96 ENSDART00000152431
grid1b
glutamate receptor, ionotropic, delta 1b
chr10_+_37981471 14.95 ENSDART00000113112
ENSDART00000185102
wscd1b
WSC domain containing 1b
chr1_+_20635190 14.67 ENSDART00000145418
ENSDART00000148518
ENSDART00000139461
ENSDART00000102969
ENSDART00000166479
spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr17_-_24717925 14.60 ENSDART00000153725
si:ch211-15d5.11
si:ch211-15d5.11
chr10_-_21054059 14.30 ENSDART00000139733
pcdh1a
protocadherin 1a
chr12_+_26621906 14.28 ENSDART00000158440
ENSDART00000046959
arhgap12b
Rho GTPase activating protein 12b
chr19_-_25301711 14.20 ENSDART00000175739
rims3
regulating synaptic membrane exocytosis 3
chr20_-_33790003 14.17 ENSDART00000020183
fam102bb
family with sequence similarity 102, member B, b
chr25_-_4733221 14.09 ENSDART00000172689
drd4a
dopamine receptor D4a
chr10_-_27223827 13.93 ENSDART00000185138
auts2a
autism susceptibility candidate 2a
chr7_+_4162994 13.81 ENSDART00000172800
si:ch211-63p21.1
si:ch211-63p21.1
chr2_+_46032678 13.71 ENSDART00000184382
ENSDART00000125971
gpc1b
glypican 1b
chr17_-_3986236 13.65 ENSDART00000188794
ENSDART00000160830
PLCB1
si:ch1073-140o9.2
chr6_+_52350443 13.13 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
si:ch211-239j9.1
chr3_-_1204341 12.79 ENSDART00000089646
fam234b
family with sequence similarity 234, member B
chr9_+_21843915 12.79 ENSDART00000101977
kctd12.1
potassium channel tetramerisation domain containing 12.1
chr3_+_17744339 12.76 ENSDART00000132622
znf385c
zinc finger protein 385C
chr16_+_49601838 12.75 ENSDART00000168570
ENSDART00000159236
si:dkey-82o10.4
si:dkey-82o10.4
chr19_+_41075488 12.64 ENSDART00000138687
ppp1r9a
protein phosphatase 1, regulatory subunit 9A
chr11_-_36765834 12.44 ENSDART00000002055
cacna2d3
calcium channel, voltage dependent, alpha2/delta subunit 3
chr24_+_39227519 12.42 ENSDART00000184611
ENSDART00000193494
ENSDART00000190728
ENSDART00000168705
MPRIP
si:ch73-103b11.2
chr1_-_23157583 12.36 ENSDART00000144208
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr22_+_4488454 12.30 ENSDART00000170620
ctxn1
cortexin 1
chr2_+_38742338 12.22 ENSDART00000177290
carmil3
capping protein regulator and myosin 1 linker 3
chr8_+_23916647 12.21 ENSDART00000143152
cpne5a
copine Va
chr4_+_2482046 12.18 ENSDART00000103371
zdhhc17
zinc finger, DHHC-type containing 17
chr23_-_32129569 12.11 ENSDART00000167761
ENSDART00000139569
zgc:92658
zgc:92658
chr7_-_52334429 11.99 ENSDART00000187372
CR938716.1

chr18_+_6857071 11.80 ENSDART00000018735
ENSDART00000181969
dnaja2l
DnaJ (Hsp40) homolog, subfamily A, member 2, like
chr13_+_29773153 11.74 ENSDART00000144443
ENSDART00000133796
ENSDART00000141310
ENSDART00000139782
pax2a
paired box 2a
chr22_-_29586608 11.74 ENSDART00000059869
adra2a
adrenoceptor alpha 2A
chr7_-_47850702 11.69 ENSDART00000109511
si:ch211-186j3.6
si:ch211-186j3.6
chr21_-_45210092 11.58 ENSDART00000066373
vdac1
voltage-dependent anion channel 1
chr9_-_44289636 11.37 ENSDART00000110411
cerkl
ceramide kinase-like
chr17_-_20287530 11.35 ENSDART00000078703
ENSDART00000191289
add3b
adducin 3 (gamma) b
chr24_-_35699595 11.34 ENSDART00000167990
mapre2
microtubule-associated protein, RP/EB family, member 2
chr12_-_30032188 11.30 ENSDART00000042514
atrnl1b
attractin-like 1b
chr9_+_53707240 11.25 ENSDART00000171490
PCDH8
si:ch211-199f5.1
chr11_-_36765376 11.20 ENSDART00000163210
cacna2d3
calcium channel, voltage dependent, alpha2/delta subunit 3
chr20_+_48782068 11.19 ENSDART00000159275
nkx2.2b
NK2 homeobox 2b
chr25_+_26923193 11.16 ENSDART00000187364
grm8b
glutamate receptor, metabotropic 8b
chr22_+_12431608 11.14 ENSDART00000108609
rnd3a
Rho family GTPase 3a
chr11_+_355305 11.06 ENSDART00000147426
pdrg1
p53 and DNA-damage regulated 1
chr10_-_37075361 10.98 ENSDART00000132023
myo18aa
myosin XVIIIAa
chr14_-_2209742 10.88 ENSDART00000054889
pcdh2ab5
protocadherin 2 alpha b 5
chr11_-_19694334 10.86 ENSDART00000054735
SYNPR
si:dkey-30j16.3
chr3_-_21348478 10.72 ENSDART00000114906
fam171a2a
family with sequence similarity 171, member A2a
chr25_+_3677650 10.72 ENSDART00000154348
prnprs3
prion protein, related sequence 3
chr3_-_43356082 10.70 ENSDART00000171213
uncx
UNC homeobox
chr17_-_45254585 10.65 ENSDART00000185507
ENSDART00000172080
ttbk2a
tau tubulin kinase 2a
chr20_-_40119872 10.52 ENSDART00000191569
nkain2
sodium/potassium transporting ATPase interacting 2
chr14_-_9056066 10.48 ENSDART00000139669
ENSDART00000138758
ENSDART00000041099
sybl1
synaptobrevin-like 1
chr4_-_3145359 10.41 ENSDART00000112210
plekha5
pleckstrin homology domain containing, family A member 5
chr17_-_35352690 10.40 ENSDART00000016053
rnf144aa
ring finger protein 144aa
chr24_-_25673405 10.30 ENSDART00000186081
ENSDART00000110241
ENSDART00000142351
cnksr2a
connector enhancer of kinase suppressor of Ras 2a
chr7_+_39011355 10.00 ENSDART00000173855
dgkza
diacylglycerol kinase, zeta a
chr5_-_37881345 9.90 ENSDART00000084819
arhgap35b
Rho GTPase activating protein 35b
chr7_+_74141297 9.85 ENSDART00000164992
rbpms
RNA binding protein with multiple splicing
chr22_+_28803739 9.80 ENSDART00000129476
ENSDART00000189726
tp53bp2b
tumor protein p53 binding protein, 2b
chr19_-_307246 9.79 ENSDART00000145916
lingo4a
leucine rich repeat and Ig domain containing 4a
chr21_-_33995710 9.75 ENSDART00000100508
ENSDART00000179622
ebf1b
early B cell factor 1b
chr2_+_40294313 9.65 ENSDART00000037292
epha4b
eph receptor A4b
chr3_-_30434016 9.58 ENSDART00000150958
lrrc4ba
leucine rich repeat containing 4Ba
chr4_-_2036620 9.50 ENSDART00000150490
si:dkey-97m3.1
si:dkey-97m3.1
chr6_-_957830 9.50 ENSDART00000090019
ENSDART00000184286
zeb2b
zinc finger E-box binding homeobox 2b
chr19_+_19028633 9.50 ENSDART00000158618
cpne4b
copine IVb
chr20_+_38322444 9.48 ENSDART00000161741
ENSDART00000132241
ENSDART00000148936
ENSDART00000149623
stum
stum, mechanosensory transduction mediator homolog
chr15_+_36941490 9.47 ENSDART00000172664
kirrel3l
kirre like nephrin family adhesion molecule 3, like
chr5_+_31995683 9.24 ENSDART00000139744
scai
suppressor of cancer cell invasion
chr10_-_120580 9.11 ENSDART00000053702
ripply3
ripply transcriptional repressor 3
chr7_+_73593814 9.11 ENSDART00000110544
znf219
zinc finger protein 219
chr2_-_45154550 9.08 ENSDART00000148595
ENSDART00000150002
capn10
calpain 10
chr24_-_35699444 9.00 ENSDART00000166567
mapre2
microtubule-associated protein, RP/EB family, member 2
chr14_+_3411771 8.99 ENSDART00000164778
trpc3
transient receptor potential cation channel, subfamily C, member 3
chr14_-_9355177 8.95 ENSDART00000138535
fam46d
family with sequence similarity 46, member D
chr12_-_35885349 8.74 ENSDART00000085662
cep131
centrosomal protein 131
chr9_+_8929764 8.58 ENSDART00000102562
ankrd10b
ankyrin repeat domain 10b
chr22_-_718615 8.52 ENSDART00000149320
arl8a
ADP-ribosylation factor-like 8A
chr17_+_24718272 8.39 ENSDART00000007271
mtfr1l
mitochondrial fission regulator 1-like
chr19_+_14059349 8.37 ENSDART00000166230
tpbga
trophoblast glycoprotein a
chr2_+_36046126 8.35 ENSDART00000085976
ENSDART00000171680
smg7
SMG7 nonsense mediated mRNA decay factor
chr17_+_15983247 8.30 ENSDART00000154275
clmn
calmin
chr21_-_33995213 8.27 ENSDART00000140184
EBF1 (1 of many)
si:ch211-51e8.2
chr1_-_47771742 8.26 ENSDART00000101079
neurl1aa
neuralized E3 ubiquitin protein ligase 1Aa
chr24_+_16393302 8.23 ENSDART00000188670
ENSDART00000081759
ENSDART00000177790
sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr25_-_20381107 8.21 ENSDART00000067454
kctd15a
potassium channel tetramerization domain containing 15a
chr8_-_24135171 8.08 ENSDART00000112926
adora1b
adenosine A1 receptor b
chr1_-_53700392 8.03 ENSDART00000127216
fam161a
family with sequence similarity 161, member A

Network of associatons between targets according to the STRING database.

First level regulatory network of zbtb14

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
16.7 83.7 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
11.1 33.4 GO:1903646 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
7.8 39.1 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
7.5 37.3 GO:0061551 trigeminal ganglion development(GO:0061551)
6.3 25.1 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
5.4 16.3 GO:0072579 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
5.2 15.7 GO:0044406 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
5.1 15.3 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
5.1 30.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
5.0 35.2 GO:0021534 cell proliferation in hindbrain(GO:0021534)
4.6 18.5 GO:0006843 mitochondrial citrate transport(GO:0006843)
4.1 73.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
4.1 36.5 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
3.8 11.4 GO:2000425 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176) regulation of apoptotic cell clearance(GO:2000425)
3.2 50.6 GO:0008053 mitochondrial fusion(GO:0008053)
2.7 51.4 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
2.7 10.7 GO:0021731 trigeminal motor nucleus development(GO:0021731)
2.6 23.6 GO:0043217 myelin maintenance(GO:0043217)
2.6 33.8 GO:0021754 facial nucleus development(GO:0021754)
2.6 33.7 GO:0048899 anterior lateral line development(GO:0048899)
2.6 12.8 GO:0051204 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
2.5 17.8 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
2.3 11.7 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
2.3 93.8 GO:0046847 filopodium assembly(GO:0046847)
2.3 9.1 GO:0051012 microtubule sliding(GO:0051012)
2.1 17.0 GO:0051963 regulation of synapse assembly(GO:0051963)
2.1 8.4 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
2.0 12.2 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
1.9 19.4 GO:0032288 myelin assembly(GO:0032288)
1.9 98.8 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
1.9 92.9 GO:0036269 swimming behavior(GO:0036269)
1.9 35.2 GO:1990090 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
1.7 5.0 GO:0009397 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
1.5 11.7 GO:0021588 cerebellum formation(GO:0021588)
1.4 7.1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
1.3 6.4 GO:0060544 regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544)
1.3 15.4 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
1.3 6.3 GO:0090200 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
1.2 7.5 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
1.2 8.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
1.2 9.7 GO:0070571 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
1.2 22.5 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
1.1 11.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
1.1 15.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
1.0 23.8 GO:0006595 polyamine metabolic process(GO:0006595)
1.0 5.8 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.9 27.6 GO:0006829 zinc II ion transport(GO:0006829)
0.9 9.1 GO:0003139 secondary heart field specification(GO:0003139)
0.9 5.3 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.8 19.3 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.8 8.9 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.8 11.2 GO:0033505 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.8 1.5 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.8 26.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.7 4.5 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.7 28.0 GO:0060037 pharyngeal system development(GO:0060037)
0.7 8.1 GO:0035587 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.7 21.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.7 4.7 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.6 4.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.6 2.9 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.6 5.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.6 4.0 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.6 45.7 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.6 13.9 GO:0021884 forebrain neuron development(GO:0021884)
0.6 9.5 GO:0072176 pronephric duct development(GO:0039022) nephric duct development(GO:0072176)
0.6 12.8 GO:0021986 habenula development(GO:0021986)
0.5 8.4 GO:0000266 mitochondrial fission(GO:0000266)
0.5 5.7 GO:0030431 sleep(GO:0030431)
0.5 5.1 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.5 1.5 GO:0070417 cellular response to cold(GO:0070417)
0.5 1.5 GO:0009193 ribonucleoside diphosphate catabolic process(GO:0009191) pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.5 22.2 GO:0032456 endocytic recycling(GO:0032456)
0.5 11.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.5 9.5 GO:0060030 dorsal convergence(GO:0060030)
0.4 4.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.4 13.8 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.4 22.2 GO:0001885 endothelial cell development(GO:0001885)
0.4 10.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.4 25.7 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.4 12.0 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.4 20.9 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.4 3.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.4 23.3 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.4 21.7 GO:0071277 cellular response to calcium ion(GO:0071277)
0.4 2.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.3 1.4 GO:0045023 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.3 5.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.3 6.0 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.3 41.7 GO:0090630 activation of GTPase activity(GO:0090630)
0.3 49.3 GO:0048675 axon extension(GO:0048675)
0.3 1.2 GO:0031053 primary miRNA processing(GO:0031053)
0.3 3.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.3 6.6 GO:0006828 manganese ion transport(GO:0006828)
0.3 11.0 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.3 11.1 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.3 3.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.3 4.7 GO:0072160 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014) nephron tubule epithelial cell differentiation(GO:0072160)
0.3 10.5 GO:0008333 endosome to lysosome transport(GO:0008333)
0.3 51.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 8.4 GO:0021954 central nervous system neuron development(GO:0021954)
0.2 42.1 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.2 9.0 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.2 10.4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.2 3.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 9.3 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.2 6.6 GO:0001706 endoderm formation(GO:0001706)
0.2 0.6 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.2 10.5 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.2 6.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.2 8.1 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.2 23.8 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.2 2.7 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 5.7 GO:0045332 phospholipid translocation(GO:0045332)
0.2 18.1 GO:0051260 protein homooligomerization(GO:0051260)
0.2 2.0 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.2 15.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 9.1 GO:0030903 notochord development(GO:0030903)
0.1 0.8 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 4.7 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.5 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.1 4.5 GO:0048634 regulation of muscle organ development(GO:0048634)
0.1 14.6 GO:0006979 response to oxidative stress(GO:0006979)
0.1 14.8 GO:0016485 protein processing(GO:0016485)
0.1 0.6 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.1 3.6 GO:0021545 cranial nerve development(GO:0021545)
0.1 1.1 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 0.4 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.1 0.7 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 4.1 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 11.6 GO:0098656 anion transmembrane transport(GO:0098656)
0.1 1.2 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 5.3 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.1 4.6 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344) response to fibroblast growth factor(GO:0071774)
0.1 1.4 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.1 5.6 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.1 1.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 3.9 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.1 17.2 GO:0006470 protein dephosphorylation(GO:0006470)
0.1 1.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 1.6 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 7.0 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.1 11.8 GO:0006869 lipid transport(GO:0006869)
0.1 3.9 GO:0016358 dendrite development(GO:0016358)
0.1 9.8 GO:0043087 regulation of GTPase activity(GO:0043087)
0.1 6.8 GO:0044782 cilium organization(GO:0044782)
0.1 5.5 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1 14.0 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.1 3.3 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 3.2 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 16.8 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.0 12.7 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 5.2 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.4 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 8.9 GO:0042060 wound healing(GO:0042060)
0.0 1.9 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.2 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 1.0 GO:0008643 carbohydrate transport(GO:0008643)
0.0 4.0 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.3 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 1.7 GO:0030162 regulation of proteolysis(GO:0030162)
0.0 2.1 GO:0006914 autophagy(GO:0006914)
0.0 1.4 GO:0048511 rhythmic process(GO:0048511)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
11.1 33.4 GO:0072380 TRC complex(GO:0072380)
5.1 51.4 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
4.1 61.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
3.2 50.6 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
2.6 64.1 GO:0031594 neuromuscular junction(GO:0031594)
2.4 19.4 GO:0033010 paranodal junction(GO:0033010)
2.4 58.9 GO:0043195 terminal bouton(GO:0043195)
2.3 9.1 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
2.0 8.0 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
1.9 22.3 GO:0044295 axonal growth cone(GO:0044295)
1.8 26.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.6 39.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
1.6 69.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
1.5 15.4 GO:0036449 microtubule minus-end(GO:0036449)
1.4 36.5 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
1.4 64.9 GO:0042734 presynaptic membrane(GO:0042734)
1.2 11.1 GO:0016272 prefoldin complex(GO:0016272)
1.2 15.9 GO:0005922 connexon complex(GO:0005922)
1.2 8.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
1.2 22.5 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
1.0 4.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
1.0 15.5 GO:0044306 axon terminus(GO:0043679) neuron projection terminus(GO:0044306)
0.9 8.7 GO:0001669 acrosomal vesicle(GO:0001669) centriolar satellite(GO:0034451)
0.7 3.7 GO:0030314 junctional membrane complex(GO:0030314)
0.7 6.2 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.7 21.8 GO:0032589 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.6 22.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.5 6.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.5 18.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.5 61.4 GO:0099572 postsynaptic specialization(GO:0099572)
0.5 11.6 GO:0046930 pore complex(GO:0046930)
0.4 78.4 GO:0034703 cation channel complex(GO:0034703)
0.4 4.6 GO:0030904 retromer complex(GO:0030904)
0.4 2.0 GO:0005899 insulin receptor complex(GO:0005899)
0.4 37.5 GO:0005882 intermediate filament(GO:0005882)
0.3 21.9 GO:0043025 neuronal cell body(GO:0043025)
0.3 6.7 GO:0035102 PRC1 complex(GO:0035102)
0.3 43.3 GO:0030424 axon(GO:0030424)
0.3 19.4 GO:0031902 late endosome membrane(GO:0031902)
0.2 4.3 GO:0005801 cis-Golgi network(GO:0005801)
0.2 5.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 0.7 GO:0097361 CIA complex(GO:0097361)
0.2 14.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 4.5 GO:0008278 cohesin complex(GO:0008278)
0.2 10.5 GO:0031201 SNARE complex(GO:0031201)
0.2 3.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 7.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 39.3 GO:0005911 cell-cell junction(GO:0005911)
0.2 6.3 GO:0016605 PML body(GO:0016605)
0.2 5.5 GO:0035869 ciliary transition zone(GO:0035869)
0.2 70.3 GO:0000139 Golgi membrane(GO:0000139)
0.1 1.5 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 45.4 GO:0005874 microtubule(GO:0005874)
0.1 5.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 16.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 42.3 GO:0043005 neuron projection(GO:0043005)
0.1 2.6 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 4.5 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 22.8 GO:0005813 centrosome(GO:0005813)
0.1 3.9 GO:0005930 axoneme(GO:0005930)
0.1 8.5 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 11.7 GO:0005929 cilium(GO:0005929)
0.1 0.5 GO:0032797 SMN complex(GO:0032797)
0.1 12.9 GO:0005938 cell cortex(GO:0005938) cytoplasmic region(GO:0099568)
0.1 24.2 GO:0005667 transcription factor complex(GO:0005667)
0.1 81.2 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 14.6 GO:0030054 cell junction(GO:0030054)
0.1 1.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 32.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.2 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 8.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.1 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 146.9 GO:0016020 membrane(GO:0016020)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
27.9 83.7 GO:0031835 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
12.6 37.7 GO:0072591 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
6.0 23.8 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
5.9 35.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
5.4 16.3 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
5.1 30.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
4.6 69.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
3.6 25.4 GO:0030274 LIM domain binding(GO:0030274)
3.2 15.9 GO:0055077 gap junction hemi-channel activity(GO:0055077)
3.1 61.8 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
2.6 23.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
2.6 51.4 GO:0001671 ATPase activator activity(GO:0001671)
2.5 22.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
2.4 21.9 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
2.4 19.4 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
2.4 54.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
2.3 11.6 GO:0015288 porin activity(GO:0015288)
2.1 33.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
2.0 18.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
2.0 6.0 GO:0042165 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
2.0 11.7 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
1.7 5.0 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
1.6 11.4 GO:0001727 lipid kinase activity(GO:0001727)
1.6 11.2 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
1.5 43.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
1.5 4.5 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
1.4 20.7 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
1.4 19.3 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
1.4 4.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
1.4 9.5 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
1.3 45.6 GO:0051010 microtubule plus-end binding(GO:0051010)
1.3 10.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
1.2 7.4 GO:0008502 melatonin receptor activity(GO:0008502)
1.2 15.5 GO:0031628 opioid receptor binding(GO:0031628)
1.2 15.4 GO:0030507 spectrin binding(GO:0030507)
1.2 8.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
1.1 30.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
1.1 22.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
1.1 28.6 GO:0042577 lipid phosphatase activity(GO:0042577)
1.1 5.5 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
1.0 4.2 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
1.0 13.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.9 35.1 GO:0019003 GDP binding(GO:0019003)
0.9 22.2 GO:0031267 small GTPase binding(GO:0031267)
0.9 20.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.9 15.0 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.9 5.2 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.9 49.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.8 39.9 GO:0044325 ion channel binding(GO:0044325)
0.7 29.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.7 15.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.7 10.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.7 3.6 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.6 3.8 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.6 12.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.6 16.4 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.6 13.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.6 7.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.6 30.9 GO:0019905 syntaxin binding(GO:0019905)
0.6 4.6 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.6 9.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.5 9.8 GO:0002039 p53 binding(GO:0002039)
0.5 2.6 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.5 20.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.5 15.4 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.5 3.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.4 5.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.4 19.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.4 10.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.4 50.5 GO:0005516 calmodulin binding(GO:0005516)
0.4 2.0 GO:0005009 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.4 1.5 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.4 2.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.3 4.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.3 4.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.3 17.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.3 9.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3 23.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.3 22.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.3 10.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 3.7 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.2 81.8 GO:0005096 GTPase activator activity(GO:0005096)
0.2 5.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 20.1 GO:0045296 cadherin binding(GO:0045296)
0.2 14.9 GO:0008146 sulfotransferase activity(GO:0008146)
0.2 26.5 GO:0060090 binding, bridging(GO:0060090)
0.2 2.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 11.6 GO:0019903 protein phosphatase binding(GO:0019903)
0.2 6.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.2 5.7 GO:0004707 MAP kinase activity(GO:0004707)
0.2 9.6 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 0.4 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.1 50.5 GO:0003924 GTPase activity(GO:0003924)
0.1 8.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 19.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 3.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 11.3 GO:0008201 heparin binding(GO:0008201)
0.1 4.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 20.9 GO:0046982 protein heterodimerization activity(GO:0046982)
0.1 1.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 1.5 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 22.4 GO:0030246 carbohydrate binding(GO:0030246)
0.1 2.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 23.0 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 61.1 GO:0005509 calcium ion binding(GO:0005509)
0.1 3.8 GO:0030898 microfilament motor activity(GO:0000146) actin-dependent ATPase activity(GO:0030898)
0.1 1.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 2.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 3.2 GO:0046332 SMAD binding(GO:0046332)
0.1 4.8 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 5.2 GO:0003777 microtubule motor activity(GO:0003777)
0.0 3.1 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 2.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 5.7 GO:0000287 magnesium ion binding(GO:0000287)
0.0 6.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 60.2 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 4.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.6 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 1.7 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 3.5 GO:0015293 symporter activity(GO:0015293)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 7.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 63.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
1.1 15.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
1.0 36.6 PID AURORA B PATHWAY Aurora B signaling
0.8 13.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.7 30.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.6 23.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.6 5.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.5 6.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.4 15.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.3 8.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.3 9.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.3 15.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.2 2.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.2 3.1 PID P53 REGULATION PATHWAY p53 pathway
0.1 3.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 3.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 2.1 PID BMP PATHWAY BMP receptor signaling
0.0 1.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 2.5 PID P73PATHWAY p73 transcription factor network
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 36.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
2.3 39.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
2.2 9.0 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
1.6 30.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
1.5 13.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
1.3 19.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
1.3 101.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.9 11.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.6 9.0 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.6 6.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.5 8.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.4 2.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.3 4.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.3 2.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.3 25.2 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.2 18.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 11.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.2 6.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 7.3 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.2 4.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 13.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.2 2.6 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1 5.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 3.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 5.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.1 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 8.4 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.5 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA