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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for zeb1a+zeb1b

Z-value: 5.13

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Transcription factors associated with zeb1a+zeb1b

Gene Symbol Gene ID Gene Info
zeb1b
ENSDARG00000013207 zinc finger E-box binding homeobox 1b
zeb1a
ENSDARG00000016788 zinc finger E-box binding homeobox 1a
zeb1b
ENSDARG00000113922 zinc finger E-box binding homeobox 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zeb1bdr11_v1_chr12_-_26851726_26851726-0.616.6e-11Click!
zeb1adr11_v1_chr2_-_43851915_43851915-0.533.7e-08Click!

Activity profile of zeb1a+zeb1b motif

Sorted Z-values of zeb1a+zeb1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_20239141 144.31 ENSDART00000101152
ENSDART00000152473
spint2
serine peptidase inhibitor, Kunitz type, 2
chr19_-_48312109 89.61 ENSDART00000161103
si:ch73-359m17.9
si:ch73-359m17.9
chr10_-_2942900 79.51 ENSDART00000002622
oclna
occludin a
chr22_+_661711 79.39 ENSDART00000113795
elf3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr21_-_25741411 77.48 ENSDART00000101211
cldnh
claudin h
chr21_-_38153824 72.18 ENSDART00000151226
klf5l
Kruppel-like factor 5 like
chr19_-_30404096 71.92 ENSDART00000103475
agr2
anterior gradient 2
chr2_+_68789 70.21 ENSDART00000058569
cldn1
claudin 1
chr1_-_50247 69.89 ENSDART00000168428
ildr1a
immunoglobulin-like domain containing receptor 1a
chr16_+_17715243 68.39 ENSDART00000149437
ENSDART00000149596
si:dkey-87o1.2
si:dkey-87o1.2
chr6_-_7776612 66.63 ENSDART00000190269
myh9a
myosin, heavy chain 9a, non-muscle
chr8_-_18667693 65.39 ENSDART00000100516
stap2b
signal transducing adaptor family member 2b
chr21_+_30351256 65.01 ENSDART00000078341
foxi3a
forkhead box I3a
chr22_+_661505 63.16 ENSDART00000149460
elf3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr25_-_22187397 59.74 ENSDART00000123211
ENSDART00000139110
pkp3a
plakophilin 3a
chr7_-_53117131 57.34 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cdh1
cadherin 1, type 1, E-cadherin (epithelial)
chr2_-_722156 56.62 ENSDART00000045770
ENSDART00000169498
foxq1a
forkhead box Q1a
chr15_-_33964897 56.17 ENSDART00000172075
ENSDART00000158126
ENSDART00000160456
lsr
lipolysis stimulated lipoprotein receptor
chr12_-_4243268 54.81 ENSDART00000131275
zgc:92313
zgc:92313
chr22_+_1170294 52.26 ENSDART00000159761
ENSDART00000169809
irf6
interferon regulatory factor 6
chr16_+_28792158 52.20 ENSDART00000161525
ENSDART00000027417
zgc:171704
zgc:171704
chr9_+_48007081 50.67 ENSDART00000060593
ENSDART00000099835
zgc:92380
zgc:92380
chr13_+_33606739 49.98 ENSDART00000026464
cfl1l
cofilin 1 (non-muscle), like
chr16_-_23346095 49.77 ENSDART00000160546
si:dkey-247k7.2
si:dkey-247k7.2
chr1_-_45177373 48.55 ENSDART00000143142
ENSDART00000034549
zgc:111983
zgc:111983
chr1_+_56180416 48.21 ENSDART00000089358
crb3b
crumbs homolog 3b
chr18_-_7539166 48.03 ENSDART00000133541
si:dkey-30c15.2
si:dkey-30c15.2
chr22_-_15578402 45.69 ENSDART00000062986
hsh2d
hematopoietic SH2 domain containing
chr5_-_65021736 44.78 ENSDART00000162368
ENSDART00000161876
anxa1c
annexin A1c
chr22_-_17677947 44.39 ENSDART00000139911
tjp3
tight junction protein 3
chr5_-_37959874 44.07 ENSDART00000031719
mpzl2b
myelin protein zero-like 2b
chr19_+_791538 43.74 ENSDART00000146554
ENSDART00000138406
tmem79a
transmembrane protein 79a
chr16_-_26676685 42.63 ENSDART00000103431
esrp1
epithelial splicing regulatory protein 1
chr25_+_22107643 42.47 ENSDART00000089680
sigirr
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr14_-_33277743 42.30 ENSDART00000048130
stard14
START domain containing 14
chr19_-_30403922 41.26 ENSDART00000181841
agr2
anterior gradient 2
chr16_+_28754403 40.98 ENSDART00000103340
s100v1
S100 calcium binding protein V1
chr21_-_25741096 40.57 ENSDART00000181756
cldnh
claudin h
chr15_+_36096689 40.24 ENSDART00000049849
col4a3
collagen, type IV, alpha 3
chr13_-_21672131 40.24 ENSDART00000067537
elovl6l
ELOVL family member 6, elongation of long chain fatty acids like
chr22_+_11756040 39.79 ENSDART00000105808
krt97
keratin 97
chr3_+_49021079 39.69 ENSDART00000162012
zgc:163083
zgc:163083
chr12_-_46228023 39.60 ENSDART00000153455
si:ch211-226h7.6
si:ch211-226h7.6
chr21_-_7928101 39.45 ENSDART00000151543
ENSDART00000114982
f2rl1.2
coagulation factor II (thrombin) receptor-like 1, tandem duplicate 2
chr7_+_22680560 38.93 ENSDART00000133761
ponzr4
plac8 onzin related protein 4
chr12_-_11349899 38.25 ENSDART00000079645
zgc:174164
zgc:174164
chr6_+_103361 37.56 ENSDART00000151899
ldlrb
low density lipoprotein receptor b
chr17_+_24843401 37.47 ENSDART00000110179
cx34.4
connexin 34.4
chr23_-_41651759 37.09 ENSDART00000146808
si:ch73-184c24.1
si:ch73-184c24.1
chr17_-_30652738 37.07 ENSDART00000154960
sh3yl1
SH3 and SYLF domain containing 1
chr3_-_61162750 36.34 ENSDART00000055064
pvalb8
parvalbumin 8
chr11_+_10984293 35.66 ENSDART00000065933
itgb6
integrin, beta 6
chr7_+_14291323 35.61 ENSDART00000053521
rhcga
Rh family, C glycoprotein a
chr7_+_32901658 35.59 ENSDART00000115420
ano9b
anoctamin 9b
chr1_+_26411496 35.53 ENSDART00000112263
arhgef38
Rho guanine nucleotide exchange factor (GEF) 38
chr14_-_33278084 35.16 ENSDART00000132850
stard14
START domain containing 14
chr5_-_37900350 34.96 ENSDART00000084839
ENSDART00000084841
ENSDART00000133437
tmprss13b
transmembrane protease, serine 13b
chr21_-_7940043 34.55 ENSDART00000099733
ENSDART00000136671
f2rl1.1
coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1
chr10_+_17776981 34.48 ENSDART00000141693
ccl19b
chemokine (C-C motif) ligand 19b
chr17_+_2549503 34.48 ENSDART00000156843
si:dkey-248g15.3
si:dkey-248g15.3
chr1_+_55002583 33.83 ENSDART00000037250
si:ch211-196h16.12
si:ch211-196h16.12
chr16_-_20312146 33.15 ENSDART00000134980
si:dkeyp-86h10.3
si:dkeyp-86h10.3
chr16_+_17714664 33.00 ENSDART00000149042
si:dkey-87o1.2
si:dkey-87o1.2
chr19_-_48010490 32.65 ENSDART00000159938
FBXL19
zgc:158376
chr14_+_48862987 32.42 ENSDART00000167810
zgc:154054
zgc:154054
chr19_-_40198478 31.99 ENSDART00000191736
grn2
granulin 2
chr20_-_3238110 31.84 ENSDART00000008077
spint1b
serine peptidase inhibitor, Kunitz type 1 b
chr19_-_10771558 31.48 ENSDART00000085165
slc9a3.2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3, tandem duplicate 2
chr16_-_25233515 31.33 ENSDART00000058943
zgc:110182
zgc:110182
chr17_-_32426392 30.97 ENSDART00000148455
ENSDART00000149885
ENSDART00000179314
grhl1
grainyhead-like transcription factor 1
chr16_-_45235947 30.81 ENSDART00000164436
si:dkey-33i11.4
si:dkey-33i11.4
chr1_+_1789357 30.66 ENSDART00000006449
atp1a1a.2
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 2
chr5_+_26212621 30.58 ENSDART00000134432
oclnb
occludin b
chr19_+_7567763 30.46 ENSDART00000140411
s100a11
S100 calcium binding protein A11
chr14_+_3495542 30.04 ENSDART00000168934
gstp2
glutathione S-transferase pi 2
chr5_+_57658898 29.68 ENSDART00000074268
ENSDART00000124568
zgc:153929
zgc:153929
chr12_-_46252062 29.46 ENSDART00000153223
si:ch211-226h7.5
si:ch211-226h7.5
chr8_-_38022298 29.41 ENSDART00000067809
rab11fip1a
RAB11 family interacting protein 1 (class I) a
chr3_+_21189766 29.32 ENSDART00000078807
zgc:123295
zgc:123295
chr19_-_5332784 29.14 ENSDART00000010373
krt1-19d
keratin, type 1, gene 19d
chr11_+_11504014 29.11 ENSDART00000104264
ENSDART00000134806
ENSDART00000132291
zgc:171226
zgc:171226
chr24_+_26006730 29.06 ENSDART00000140384
ENSDART00000139184
ccl20b
chemokine (C-C motif) ligand 20b
chr10_-_35149513 28.88 ENSDART00000063434
ENSDART00000131291
ripk4
receptor-interacting serine-threonine kinase 4
chr22_+_3914318 28.79 ENSDART00000188774
ENSDART00000082034
FO904903.1
Danio rerio major histocompatibility complex class I ULA (mhc1ula), mRNA.
chr9_+_7358749 28.64 ENSDART00000081660
ihha
Indian hedgehog homolog a
chr5_-_30615901 28.63 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr3_-_19561058 28.44 ENSDART00000079323
zgc:163079
zgc:163079
chr17_+_26965351 28.24 ENSDART00000114215
ENSDART00000147192
grhl3
grainyhead-like transcription factor 3
chr24_-_8831866 28.24 ENSDART00000066780
ENSDART00000143501
gcm2
glial cells missing homolog 2 (Drosophila)
chr1_+_54865552 27.73 ENSDART00000145381
si:ch211-196h16.5
si:ch211-196h16.5
chr20_-_42702832 27.50 ENSDART00000134689
ENSDART00000045816
plg
plasminogen
chr11_+_37216668 27.41 ENSDART00000173076
zgc:112265
zgc:112265
chr7_-_34265481 27.38 ENSDART00000173596
si:ch211-98n17.5
si:ch211-98n17.5
chr13_+_24750078 26.79 ENSDART00000021053
col17a1b
collagen, type XVII, alpha 1b
chr25_+_10416583 26.73 ENSDART00000073907
ehf
ets homologous factor
chr16_+_23960933 26.40 ENSDART00000146077
apoeb
apolipoprotein Eb
chr1_+_1838164 26.25 ENSDART00000006013
atp1a1a.5
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 5
chr18_-_46354269 26.15 ENSDART00000010813
foxa3
forkhead box A3
chr11_-_11518469 26.07 ENSDART00000104254
krt15
keratin 15
chr17_-_26867725 26.00 ENSDART00000153590
si:dkey-221l4.10
si:dkey-221l4.10
chr25_-_169291 25.99 ENSDART00000128344
lipcb
lipase, hepatic b
chr7_+_22657566 25.95 ENSDART00000141048
ponzr5
plac8 onzin related protein 5
chr1_-_59313465 25.92 ENSDART00000158067
ENSDART00000159419
txndc11
thioredoxin domain containing 11
chr7_+_66565930 25.82 ENSDART00000154597
tmem176l.3b
transmembrane protein 176l.3b
chr12_+_5708400 25.79 ENSDART00000017191
dlx3b
distal-less homeobox 3b
chr3_-_27647845 25.78 ENSDART00000151625
si:ch211-157c3.4
si:ch211-157c3.4
chr3_-_50139860 25.74 ENSDART00000101563
btr02
bloodthirsty-related gene family, member 2
chr16_+_23961276 25.74 ENSDART00000192754
apoeb
apolipoprotein Eb
chr18_+_44703343 25.73 ENSDART00000131510
b3gnt2l
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2, like
chr24_-_40731305 25.66 ENSDART00000172073
CU633479.6

chr1_+_58922027 25.65 ENSDART00000159479
trip10b
thyroid hormone receptor interactor 10b
chr8_+_2478862 25.50 ENSDART00000131739
si:dkeyp-51b9.3
si:dkeyp-51b9.3
chr21_-_17956739 25.30 ENSDART00000148154
stx2a
syntaxin 2a
chr7_-_26571994 25.22 ENSDART00000128801
si:dkey-62k3.6
si:dkey-62k3.6
chr9_+_17309195 25.15 ENSDART00000048548
scel
sciellin
chr19_-_977849 25.04 ENSDART00000172303
CABZ01088282.1

chr7_+_49654588 24.90 ENSDART00000025451
ENSDART00000141934
rassf7b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr5_-_55981288 24.79 ENSDART00000146616
si:dkey-189h5.6
si:dkey-189h5.6
chr3_-_39488482 24.72 ENSDART00000135192
zgc:100868
zgc:100868
chr3_-_39488639 24.65 ENSDART00000161644
zgc:100868
zgc:100868
chr14_+_14568437 24.63 ENSDART00000164749
pcdh20
protocadherin 20
chr14_+_15155684 24.61 ENSDART00000167966
zgc:158852
zgc:158852
chr18_-_7539469 24.41 ENSDART00000101296
si:dkey-30c15.2
si:dkey-30c15.2
chr4_-_20181964 24.32 ENSDART00000022539
fgl2a
fibrinogen-like 2a
chr23_-_31428763 24.11 ENSDART00000053545
zgc:153284
zgc:153284
chr18_-_48530221 24.02 ENSDART00000188134
ENSDART00000142107
kcnj1a.2
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 2
chr6_-_7769178 24.01 ENSDART00000191701
ENSDART00000149823
myh9a
myosin, heavy chain 9a, non-muscle
chr11_-_18254 24.00 ENSDART00000167814
prr13
proline rich 13
chr10_-_2943474 23.91 ENSDART00000188698
oclna
occludin a
chr18_-_29925717 23.91 ENSDART00000099281
mhc2dbb
major histocompatibility complex class II DBB gene
chr21_+_11244068 23.84 ENSDART00000163432
arid6
AT-rich interaction domain 6
chr22_+_22021936 23.71 ENSDART00000149586
gna15.1
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1
chr16_+_23960744 23.41 ENSDART00000058965
apoeb
apolipoprotein Eb
chr11_-_18449 23.19 ENSDART00000172050
prr13
proline rich 13
chr2_-_29996036 23.14 ENSDART00000020792
cnpy1
canopy1
chr2_-_8648440 23.07 ENSDART00000135743
si:ch211-71m22.3
si:ch211-71m22.3
chr2_-_47620806 23.05 ENSDART00000038228
ap1s3b
adaptor-related protein complex 1, sigma 3 subunit, b
chr17_+_25332711 23.02 ENSDART00000082319
tmem54a
transmembrane protein 54a
chr11_-_669558 23.02 ENSDART00000173450
pparg
peroxisome proliferator-activated receptor gamma
chr22_-_3914162 23.00 ENSDART00000187174
ENSDART00000190612
ENSDART00000187928
ENSDART00000057224
ENSDART00000184758
mhc1uma
major histocompatibility complex class I UMA
chr2_-_58075414 22.98 ENSDART00000161920
nectin4
nectin cell adhesion molecule 4
chr16_-_46664465 22.96 ENSDART00000135364
tmem176l.4
transmembrane protein 176l.4
chr10_+_2715548 22.93 ENSDART00000130793
grk5
G protein-coupled receptor kinase 5
chr20_+_15015557 22.93 ENSDART00000039345
myoc
myocilin
chr4_+_18843015 22.89 ENSDART00000152086
ENSDART00000066977
ENSDART00000132567
bik
BCL2 interacting killer
chr24_-_20444844 22.88 ENSDART00000048940
vill
villin-like
chr17_-_23709347 22.88 ENSDART00000124661
papss2a
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
chr16_+_46725087 22.69 ENSDART00000008920
rab11al
RAB11a, member RAS oncogene family, like
chr7_+_26545911 22.66 ENSDART00000135313
tnk1
tyrosine kinase, non-receptor, 1
chr11_-_669270 22.62 ENSDART00000172834
pparg
peroxisome proliferator-activated receptor gamma
chr8_-_11170114 22.48 ENSDART00000133532
si:ch211-204d2.4
si:ch211-204d2.4
chr19_+_10331325 22.31 ENSDART00000143930
tmem238a
transmembrane protein 238a
chr14_-_40821411 22.21 ENSDART00000166621
elf1
E74-like ETS transcription factor 1
chr22_-_22340688 22.12 ENSDART00000105597
si:ch211-129c21.1
si:ch211-129c21.1
chr14_+_41345175 22.12 ENSDART00000086104
nox1
NADPH oxidase 1
chr24_+_31277360 22.10 ENSDART00000165993
f3a
coagulation factor IIIa
chr23_+_31815423 22.10 ENSDART00000075730
ENSDART00000075726
myb
v-myb avian myeloblastosis viral oncogene homolog
chr16_+_40301056 22.09 ENSDART00000058578
rspo3
R-spondin 3
chr4_-_178510 22.00 ENSDART00000169805
eps8
epidermal growth factor receptor pathway substrate 8
chr2_+_49457626 21.64 ENSDART00000129967
sh3gl1a
SH3-domain GRB2-like 1a
chr8_+_47099033 21.59 ENSDART00000142979
arhgef16
Rho guanine nucleotide exchange factor (GEF) 16
chr3_+_36424055 21.55 ENSDART00000170318
si:ch1073-443f11.2
si:ch1073-443f11.2
chr25_-_32311048 21.31 ENSDART00000181806
ENSDART00000086334
CU372926.1

chr21_-_25295087 21.20 ENSDART00000087910
ENSDART00000147860
st14b
suppression of tumorigenicity 14 (colon carcinoma) b
chr21_-_11996769 21.17 ENSDART00000143537
zgc:64106
zgc:64106
chr19_-_34979837 20.97 ENSDART00000044838
ndrg1a
N-myc downstream regulated 1a
chr20_-_17041025 20.95 ENSDART00000063764
si:dkey-5n18.1
si:dkey-5n18.1
chr1_-_52437056 20.94 ENSDART00000138337
si:ch211-217k17.12
si:ch211-217k17.12
chr20_-_35578435 20.93 ENSDART00000142444
adgrf6
adhesion G protein-coupled receptor F6
chr8_-_3312384 20.89 ENSDART00000035965
fut9b
fucosyltransferase 9b
chr16_+_38201840 20.85 ENSDART00000044971
myo1eb
myosin IE, b
chr16_-_31976269 20.80 ENSDART00000139664
styk1
serine/threonine/tyrosine kinase 1
chr24_-_31904924 20.72 ENSDART00000156060
ENSDART00000129741
ENSDART00000154276
si:ch73-78o10.1
si:ch73-78o10.1
chr16_+_23947196 20.70 ENSDART00000103190
ENSDART00000132961
ENSDART00000147690
ENSDART00000142168
apoa4b.2
apolipoprotein A-IV b, tandem duplicate 2
chr6_+_584632 20.66 ENSDART00000151150
zgc:92360
zgc:92360
chr16_+_35905031 20.60 ENSDART00000162411
sh3d21
SH3 domain containing 21
chr21_-_27213166 20.58 ENSDART00000146959
mark2a
MAP/microtubule affinity-regulating kinase 2a
chr20_+_26683933 20.55 ENSDART00000139852
ENSDART00000077751
foxq1b
forkhead box Q1b
chr24_-_25244637 20.55 ENSDART00000153798
hhla2b.2
HERV-H LTR-associating 2b, tandem duplicate 2
chr2_+_4208323 20.35 ENSDART00000167906
gata6
GATA binding protein 6
chr15_+_36054864 20.29 ENSDART00000156697
col4a3
collagen, type IV, alpha 3
chr18_-_977075 20.26 ENSDART00000032392
dhdhl
dihydrodiol dehydrogenase (dimeric), like
chr21_-_45882643 20.12 ENSDART00000168703
galnt10
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr5_+_29831235 20.10 ENSDART00000109660
f11r.1
F11 receptor, tandem duplicate 1
chr10_+_29259882 20.07 ENSDART00000180606
sytl2a
synaptotagmin-like 2a
chr4_-_76370630 19.92 ENSDART00000168831
ENSDART00000174313
si:ch73-158p21.3
si:ch73-158p21.3
chr6_+_36877968 19.75 ENSDART00000155187
traf3ip2l
TRAF3 interacting protein 2-like
chr3_+_32492467 19.73 ENSDART00000151329
trpm4a
transient receptor potential cation channel, subfamily M, member 4a
chr23_-_10175898 19.71 ENSDART00000146185
krt5
keratin 5
chr17_-_2039511 19.71 ENSDART00000160223
spint1a
serine peptidase inhibitor, Kunitz type 1 a
chr25_+_8356707 19.70 ENSDART00000153708
muc5.1
mucin 5.1, oligomeric mucus/gel-forming
chr24_-_36593876 19.70 ENSDART00000160901
CABZ01055365.1

chr3_-_8130491 19.69 ENSDART00000162309
si:ch211-51i16.1
si:ch211-51i16.1
chr7_+_26545502 19.66 ENSDART00000140528
tnk1
tyrosine kinase, non-receptor, 1
chr13_+_15682803 19.61 ENSDART00000188063
CR931980.1

chr13_-_36034582 19.54 ENSDART00000133565
si:dkey-157l19.2
si:dkey-157l19.2
chr23_-_37536127 19.51 ENSDART00000078253
tor1l1
torsin family 1 like 1
chr10_+_13209580 19.45 ENSDART00000000887
ENSDART00000136932
rassf6
Ras association (RalGDS/AF-6) domain family 6
chr23_+_17387325 19.36 ENSDART00000083947
ptk6b
PTK6 protein tyrosine kinase 6b
chr4_-_12725513 19.30 ENSDART00000132286
mgst1.2
microsomal glutathione S-transferase 1.2

Network of associatons between targets according to the STRING database.

First level regulatory network of zeb1a+zeb1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
25.2 75.5 GO:0071831 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
23.2 92.6 GO:0009957 epidermal cell fate specification(GO:0009957)
18.1 90.6 GO:0061439 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
16.7 50.0 GO:0030043 actin filament fragmentation(GO:0030043)
15.5 15.5 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
11.3 113.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
10.8 32.5 GO:0002369 T cell cytokine production(GO:0002369)
9.7 48.4 GO:0071763 nuclear membrane organization(GO:0071763)
9.6 48.1 GO:0010872 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873) high-density lipoprotein particle assembly(GO:0034380)
9.6 57.3 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
9.3 74.0 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
9.2 27.5 GO:0042730 fibrinolysis(GO:0042730)
8.7 26.2 GO:0048785 hatching gland development(GO:0048785)
8.6 25.8 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
8.4 67.1 GO:0072488 ammonium transmembrane transport(GO:0072488)
7.6 22.9 GO:0034035 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
7.5 45.1 GO:0003334 keratinocyte development(GO:0003334)
7.5 44.8 GO:0045628 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
7.4 51.9 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
7.3 21.9 GO:0090131 mesenchyme migration(GO:0090131)
6.4 57.2 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
5.7 34.0 GO:0003151 outflow tract morphogenesis(GO:0003151)
5.5 22.1 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
5.4 16.3 GO:0046415 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
5.4 5.4 GO:1900221 regulation of nitric-oxide synthase activity(GO:0050999) positive regulation of nitric-oxide synthase activity(GO:0051000) beta-amyloid clearance(GO:0097242) regulation of beta-amyloid clearance(GO:1900221)
5.1 51.3 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
5.1 15.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
5.0 30.0 GO:0048795 swim bladder morphogenesis(GO:0048795)
5.0 14.9 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
4.9 44.4 GO:0030104 water homeostasis(GO:0030104)
4.9 14.8 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
4.9 34.0 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
4.7 23.7 GO:0001773 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
4.7 14.2 GO:0019240 citrulline biosynthetic process(GO:0019240)
4.7 32.7 GO:0006953 acute-phase response(GO:0006953)
4.5 212.2 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
4.4 22.1 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
4.4 47.9 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
4.3 90.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
4.2 25.5 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
4.1 12.4 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
4.0 11.9 GO:0071896 protein localization to adherens junction(GO:0071896)
4.0 39.7 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
3.9 27.6 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
3.9 23.3 GO:0010269 response to selenium ion(GO:0010269)
3.9 11.6 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
3.8 11.5 GO:0016045 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
3.8 41.5 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
3.8 15.1 GO:0016554 cytidine to uridine editing(GO:0016554)
3.7 11.2 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
3.7 22.2 GO:0030852 regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
3.7 11.1 GO:0006958 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
3.5 17.7 GO:0070292 N-acylphosphatidylethanolamine metabolic process(GO:0070292)
3.5 13.8 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
3.4 13.4 GO:0009097 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
3.2 13.0 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
3.2 16.2 GO:0010719 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
3.1 22.0 GO:0045110 intermediate filament bundle assembly(GO:0045110)
3.0 15.2 GO:0061011 hepatic duct development(GO:0061011)
3.0 12.2 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
3.0 18.1 GO:0046874 quinolinate biosynthetic process(GO:0019805) quinolinate metabolic process(GO:0046874)
2.9 46.4 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
2.9 17.4 GO:0070254 mucus secretion(GO:0070254)
2.9 5.8 GO:0000052 citrulline metabolic process(GO:0000052)
2.9 25.9 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
2.8 11.4 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
2.8 8.5 GO:0006590 thyroid hormone generation(GO:0006590)
2.8 22.1 GO:0042554 superoxide anion generation(GO:0042554)
2.7 43.5 GO:0050728 negative regulation of inflammatory response(GO:0050728)
2.7 8.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
2.7 13.6 GO:0033238 regulation of cellular amino acid metabolic process(GO:0006521) regulation of cellular amine metabolic process(GO:0033238)
2.7 8.0 GO:0048496 maintenance of organ identity(GO:0048496)
2.6 7.9 GO:1903173 fatty alcohol metabolic process(GO:1903173)
2.6 18.2 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
2.6 12.9 GO:0006642 triglyceride mobilization(GO:0006642)
2.5 7.6 GO:0032060 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
2.5 15.0 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
2.5 2.5 GO:0045621 positive regulation of lymphocyte differentiation(GO:0045621)
2.4 4.9 GO:0098586 cytoplasmic pattern recognition receptor signaling pathway in response to virus(GO:0039528) cellular response to virus(GO:0098586)
2.4 14.7 GO:0032367 intracellular cholesterol transport(GO:0032367)
2.4 45.4 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
2.3 9.3 GO:2000392 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
2.3 13.9 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
2.3 6.9 GO:0042543 protein N-linked glycosylation via arginine(GO:0042543)
2.3 6.9 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
2.2 6.7 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
2.2 22.3 GO:0050688 regulation of defense response to virus(GO:0050688)
2.2 4.4 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
2.2 21.8 GO:0051601 exocyst localization(GO:0051601)
2.2 58.8 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
2.2 32.4 GO:0031641 regulation of myelination(GO:0031641)
2.1 15.0 GO:0042664 negative regulation of endodermal cell fate specification(GO:0042664)
2.1 35.6 GO:0019433 triglyceride catabolic process(GO:0019433)
2.1 6.3 GO:0043504 mitochondrial DNA repair(GO:0043504)
2.1 6.2 GO:0071470 cellular response to osmotic stress(GO:0071470)
2.1 6.2 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
2.1 14.4 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
2.1 6.2 GO:0048194 Golgi vesicle budding(GO:0048194)
2.0 8.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
2.0 42.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
2.0 10.1 GO:0090208 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867) positive regulation of triglyceride metabolic process(GO:0090208)
2.0 20.1 GO:0050892 intestinal absorption(GO:0050892)
2.0 8.0 GO:0045903 positive regulation of translational fidelity(GO:0045903)
2.0 14.0 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
2.0 8.0 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
2.0 8.0 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
2.0 8.0 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
2.0 13.9 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
2.0 13.8 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
2.0 47.2 GO:0051014 actin filament severing(GO:0051014)
2.0 17.7 GO:1990402 embryonic liver development(GO:1990402)
1.9 9.7 GO:0097039 protein linear polyubiquitination(GO:0097039)
1.9 13.5 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
1.9 32.7 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
1.9 13.4 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
1.9 49.4 GO:0043588 skin development(GO:0043588)
1.9 60.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
1.9 16.7 GO:0031126 snoRNA 3'-end processing(GO:0031126)
1.9 220.8 GO:1990266 neutrophil migration(GO:1990266)
1.8 16.5 GO:0097374 sensory neuron axon guidance(GO:0097374)
1.8 25.7 GO:0050870 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
1.8 5.5 GO:0052575 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
1.8 3.7 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
1.8 10.8 GO:0070527 platelet aggregation(GO:0070527)
1.8 7.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.8 8.8 GO:0048855 adenohypophysis morphogenesis(GO:0048855)
1.7 5.2 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
1.7 17.4 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
1.7 41.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
1.7 13.8 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
1.7 20.7 GO:2000403 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
1.7 5.1 GO:0042421 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
1.7 18.5 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
1.7 5.0 GO:0019417 sulfur oxidation(GO:0019417)
1.7 11.8 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
1.7 10.1 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
1.7 3.4 GO:0071715 icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
1.7 33.4 GO:0030183 B cell differentiation(GO:0030183)
1.7 13.3 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
1.6 3.3 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway(GO:0002753)
1.6 9.8 GO:0006013 mannose metabolic process(GO:0006013)
1.6 8.1 GO:0070301 response to acidic pH(GO:0010447) cellular response to hydrogen peroxide(GO:0070301)
1.6 8.1 GO:0098535 de novo centriole assembly(GO:0098535)
1.6 3.2 GO:0051451 myoblast migration involved in skeletal muscle regeneration(GO:0014839) myoblast migration(GO:0051451) positive regulation of lamellipodium organization(GO:1902745)
1.6 30.5 GO:0001843 neural tube closure(GO:0001843)
1.6 22.4 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
1.6 35.0 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
1.6 6.3 GO:0030224 monocyte differentiation(GO:0030224)
1.6 4.7 GO:0070285 pigment cell development(GO:0070285)
1.6 24.9 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
1.6 4.7 GO:0042119 neutrophil activation involved in immune response(GO:0002283) granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
1.5 4.6 GO:0090175 Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
1.5 4.6 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
1.5 7.6 GO:0045124 regulation of bone resorption(GO:0045124)
1.5 15.2 GO:0010890 regulation of sequestering of triglyceride(GO:0010889) positive regulation of sequestering of triglyceride(GO:0010890) sequestering of triglyceride(GO:0030730)
1.5 23.7 GO:0036065 fucosylation(GO:0036065)
1.5 5.9 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
1.5 16.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
1.5 2.9 GO:0048521 negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
1.5 33.4 GO:0017121 phospholipid scrambling(GO:0017121)
1.4 4.3 GO:0071706 tumor necrosis factor production(GO:0032640) tumor necrosis factor superfamily cytokine production(GO:0071706)
1.4 56.3 GO:0006749 glutathione metabolic process(GO:0006749)
1.4 2.9 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
1.4 8.6 GO:0046218 tryptophan metabolic process(GO:0006568) tryptophan catabolic process(GO:0006569) indolalkylamine metabolic process(GO:0006586) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
1.4 2.8 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
1.4 8.5 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
1.4 7.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
1.4 42.1 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
1.4 43.2 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
1.4 2.8 GO:0035767 endothelial cell chemotaxis(GO:0035767)
1.4 33.8 GO:0051492 regulation of stress fiber assembly(GO:0051492)
1.3 13.5 GO:0007260 tyrosine phosphorylation of STAT protein(GO:0007260) regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
1.3 37.3 GO:2001236 regulation of extrinsic apoptotic signaling pathway(GO:2001236)
1.3 6.6 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
1.3 5.3 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
1.3 10.5 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
1.3 3.9 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857) regulation of lens fiber cell differentiation(GO:1902746)
1.3 7.7 GO:0060967 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
1.3 7.7 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
1.3 12.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
1.3 6.3 GO:0001840 neural plate development(GO:0001840)
1.3 7.5 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
1.3 6.3 GO:0032776 DNA methylation on cytosine(GO:0032776)
1.2 8.7 GO:0006621 protein retention in ER lumen(GO:0006621)
1.2 2.5 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
1.2 12.4 GO:0015909 long-chain fatty acid transport(GO:0015909)
1.2 19.7 GO:0006959 humoral immune response(GO:0006959)
1.2 2.5 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
1.2 12.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
1.2 6.1 GO:0009435 NAD biosynthetic process(GO:0009435)
1.2 26.8 GO:0051923 sulfation(GO:0051923)
1.2 24.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
1.2 8.4 GO:0010155 regulation of proton transport(GO:0010155)
1.2 9.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
1.2 1.2 GO:0097065 anterior head development(GO:0097065)
1.2 16.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
1.2 4.7 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
1.2 8.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
1.2 3.5 GO:0000966 RNA 5'-end processing(GO:0000966)
1.1 8.0 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
1.1 3.4 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
1.1 9.0 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
1.1 7.9 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
1.1 4.5 GO:0038161 prolactin signaling pathway(GO:0038161)
1.1 12.2 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
1.1 9.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
1.1 9.8 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
1.1 18.5 GO:0043114 regulation of vascular permeability(GO:0043114)
1.1 20.6 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
1.1 3.2 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
1.1 16.0 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
1.1 109.9 GO:0009410 response to xenobiotic stimulus(GO:0009410)
1.1 3.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
1.1 7.4 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
1.0 10.3 GO:0046632 alpha-beta T cell differentiation(GO:0046632)
1.0 2.1 GO:0060019 radial glial cell differentiation(GO:0060019)
1.0 6.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
1.0 15.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
1.0 5.1 GO:0003173 ventriculo bulbo valve development(GO:0003173)
1.0 4.0 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.0 11.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
1.0 8.8 GO:0035141 medial fin morphogenesis(GO:0035141)
1.0 28.3 GO:0003094 glomerular filtration(GO:0003094)
1.0 28.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
1.0 2.9 GO:0000212 meiotic spindle organization(GO:0000212)
1.0 2.9 GO:0071421 manganese ion transmembrane transport(GO:0071421)
1.0 48.8 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.9 4.7 GO:0033273 response to vitamin(GO:0033273)
0.9 49.3 GO:0007492 endoderm development(GO:0007492)
0.9 5.7 GO:0006183 GTP biosynthetic process(GO:0006183)
0.9 22.7 GO:1990798 pancreas regeneration(GO:1990798)
0.9 14.0 GO:0048382 mesendoderm development(GO:0048382)
0.9 28.9 GO:0019882 antigen processing and presentation(GO:0019882)
0.9 7.4 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.9 6.4 GO:0061055 myotome development(GO:0061055)
0.9 3.7 GO:0046100 hypoxanthine metabolic process(GO:0046100)
0.9 15.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.9 7.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.9 3.5 GO:0051645 Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661)
0.9 3.5 GO:0070084 protein initiator methionine removal(GO:0070084)
0.9 2.6 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.9 12.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.9 8.6 GO:0048246 macrophage chemotaxis(GO:0048246)
0.9 17.9 GO:0060872 semicircular canal development(GO:0060872)
0.9 5.1 GO:0060036 notochord cell vacuolation(GO:0060036)
0.9 135.3 GO:0006954 inflammatory response(GO:0006954)
0.8 3.4 GO:0019068 virion assembly(GO:0019068) virus maturation(GO:0019075) multi-organism membrane organization(GO:0044803) viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.8 5.9 GO:0072098 anterior/posterior pattern specification involved in pronephros development(GO:0034672) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.8 95.9 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.8 0.8 GO:0050820 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.8 11.6 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.8 5.8 GO:0003188 heart valve formation(GO:0003188) atrioventricular valve formation(GO:0003190)
0.8 12.3 GO:0015693 magnesium ion transport(GO:0015693)
0.8 4.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.8 5.7 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.8 2.4 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519) spinal cord association neuron differentiation(GO:0021527)
0.8 13.0 GO:0048794 swim bladder development(GO:0048794)
0.8 14.5 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.8 5.6 GO:0032475 otolith formation(GO:0032475)
0.8 4.8 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.8 14.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.8 89.6 GO:0008544 epidermis development(GO:0008544)
0.8 3.2 GO:2000058 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.8 31.6 GO:0007596 blood coagulation(GO:0007596)
0.8 14.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.8 7.1 GO:0042113 B cell activation(GO:0042113)
0.8 5.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.8 12.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.8 7.7 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.8 33.1 GO:0010950 positive regulation of endopeptidase activity(GO:0010950) positive regulation of peptidase activity(GO:0010952)
0.8 16.9 GO:0015701 bicarbonate transport(GO:0015701)
0.8 11.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.8 8.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.8 3.0 GO:0097037 heme export(GO:0097037)
0.8 9.9 GO:0009303 rRNA transcription(GO:0009303)
0.8 2.3 GO:0044036 cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.8 7.6 GO:0006108 malate metabolic process(GO:0006108)
0.7 15.0 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.7 56.5 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.7 8.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.7 5.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.7 17.5 GO:0060037 pharyngeal system development(GO:0060037)
0.7 2.2 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.7 5.8 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.7 7.8 GO:0007608 sensory perception of smell(GO:0007608)
0.7 5.0 GO:0061511 centriole elongation(GO:0061511)
0.7 1.4 GO:0072526 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.7 12.6 GO:0006801 superoxide metabolic process(GO:0006801)
0.7 10.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.7 1.4 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.7 41.6 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.7 2.7 GO:0035988 chondrocyte proliferation(GO:0035988)
0.7 2.7 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.7 4.7 GO:0019731 antibacterial humoral response(GO:0019731)
0.7 11.2 GO:0030259 lipid glycosylation(GO:0030259)
0.7 5.9 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.6 5.1 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.6 6.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.6 5.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.6 37.0 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.6 14.6 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.6 4.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.6 4.4 GO:0061056 sclerotome development(GO:0061056)
0.6 9.5 GO:0018149 peptide cross-linking(GO:0018149)
0.6 117.7 GO:0045087 innate immune response(GO:0045087)
0.6 2.5 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.6 3.7 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.6 7.3 GO:0008354 germ cell migration(GO:0008354)
0.6 22.3 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.6 31.8 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.6 2.3 GO:0034982 mitochondrial protein processing(GO:0034982)
0.6 7.0 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.6 45.5 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.6 4.0 GO:0042129 regulation of T cell proliferation(GO:0042129)
0.6 8.6 GO:0009749 response to carbohydrate(GO:0009743) response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.6 1.1 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.6 2.3 GO:0021755 eurydendroid cell differentiation(GO:0021755)
0.6 9.0 GO:0042476 odontogenesis(GO:0042476)
0.6 1.7 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.6 12.4 GO:0030199 collagen fibril organization(GO:0030199)
0.6 6.1 GO:0016556 mRNA modification(GO:0016556)
0.6 2.2 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.6 5.0 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.6 8.9 GO:0051289 protein homotetramerization(GO:0051289)
0.6 1.7 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.5 4.4 GO:0010002 cardioblast differentiation(GO:0010002)
0.5 60.0 GO:0007266 Rho protein signal transduction(GO:0007266)
0.5 1.6 GO:1901052 sarcosine metabolic process(GO:1901052)
0.5 2.7 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.5 1.6 GO:0048387 negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144) negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.5 10.1 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.5 6.9 GO:0001841 neural tube formation(GO:0001841)
0.5 1.6 GO:0042220 response to cocaine(GO:0042220) cellular response to alkaloid(GO:0071312) cellular response to cocaine(GO:0071314)
0.5 20.1 GO:0042742 defense response to bacterium(GO:0042742)
0.5 2.6 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.5 2.1 GO:0046292 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.5 93.0 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.5 2.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.5 26.6 GO:0050673 epithelial cell proliferation(GO:0050673)
0.5 5.2 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.5 2.6 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.5 17.9 GO:0044259 collagen metabolic process(GO:0032963) multicellular organismal macromolecule metabolic process(GO:0044259)
0.5 16.7 GO:0007340 acrosome reaction(GO:0007340)
0.5 2.5 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.5 2.0 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.5 2.0 GO:0071867 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.5 5.5 GO:0050909 sensory perception of taste(GO:0050909)
0.5 2.0 GO:0030497 fatty acid elongation(GO:0030497)
0.5 3.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.5 2.0 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.5 5.3 GO:0097191 extrinsic apoptotic signaling pathway(GO:0097191)
0.5 3.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.5 2.4 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.5 1.4 GO:1990108 protein linear deubiquitination(GO:1990108)
0.5 2.8 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.5 2.3 GO:0032479 regulation of type I interferon production(GO:0032479) positive regulation of type I interferon production(GO:0032481) type I interferon production(GO:0032606)
0.5 5.5 GO:0042572 retinol metabolic process(GO:0042572)
0.4 1.8 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.4 12.8 GO:0031017 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.4 3.4 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.4 1.7 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.4 3.3 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.4 2.9 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.4 2.8 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.4 13.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.4 4.0 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.4 1.2 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.4 3.6 GO:0045444 fat cell differentiation(GO:0045444)
0.4 4.7 GO:0009651 response to salt stress(GO:0009651)
0.4 3.1 GO:0003323 type B pancreatic cell development(GO:0003323)
0.4 6.6 GO:0032438 melanosome organization(GO:0032438) pigment granule organization(GO:0048753)
0.4 3.0 GO:0006167 AMP biosynthetic process(GO:0006167)
0.4 3.4 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.4 1.1 GO:0007172 signal complex assembly(GO:0007172)
0.4 5.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.4 2.6 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.4 2.2 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.4 3.5 GO:0021654 rhombomere boundary formation(GO:0021654)
0.4 3.5 GO:0044206 pyrimidine-containing compound salvage(GO:0008655) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.3 3.1 GO:0050975 sensory perception of touch(GO:0050975)
0.3 2.4 GO:0006703 estrogen biosynthetic process(GO:0006703) estrogen metabolic process(GO:0008210)
0.3 3.8 GO:0006611 protein export from nucleus(GO:0006611)
0.3 3.8 GO:0036368 cone photoresponse recovery(GO:0036368)
0.3 0.3 GO:0061032 pericardium development(GO:0060039) visceral serous pericardium development(GO:0061032)
0.3 1.3 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.3 1.6 GO:0002159 desmosome assembly(GO:0002159)
0.3 1.3 GO:0071632 optomotor response(GO:0071632)
0.3 11.4 GO:0048916 posterior lateral line development(GO:0048916)
0.3 1.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797) regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.3 4.5 GO:0015781 nucleotide-sugar transport(GO:0015780) pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.3 1.3 GO:0034433 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.3 5.9 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.3 5.2 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.3 63.7 GO:0006955 immune response(GO:0006955)
0.3 2.4 GO:0021984 adenohypophysis development(GO:0021984)
0.3 3.8 GO:0042541 hemoglobin metabolic process(GO:0020027) hemoglobin biosynthetic process(GO:0042541)
0.3 2.9 GO:0033750 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.3 3.8 GO:0002574 thrombocyte differentiation(GO:0002574)
0.3 9.2 GO:0097352 autophagosome maturation(GO:0097352)
0.3 4.8 GO:0048264 determination of ventral identity(GO:0048264)
0.3 0.6 GO:0061312 BMP signaling pathway involved in heart development(GO:0061312) regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901213)
0.3 17.7 GO:0031101 fin regeneration(GO:0031101)
0.3 2.5 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.3 3.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.3 18.7 GO:0045765 regulation of angiogenesis(GO:0045765)
0.3 1.9 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.3 0.8 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.3 18.3 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.3 14.4 GO:0035304 regulation of protein dephosphorylation(GO:0035304)
0.3 2.2 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.3 1.7 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.3 0.8 GO:0006833 water transport(GO:0006833)
0.3 24.3 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.3 5.7 GO:0006826 iron ion transport(GO:0006826)
0.3 5.6 GO:0001878 response to yeast(GO:0001878) response to fungus(GO:0009620)
0.3 1.3 GO:0006031 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.3 268.0 GO:0006508 proteolysis(GO:0006508)
0.3 5.4 GO:0036303 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.3 2.0 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.3 9.1 GO:0002062 chondrocyte differentiation(GO:0002062)
0.3 1.3 GO:1904427 T-tubule organization(GO:0033292) positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of voltage-gated calcium channel activity(GO:1901387) positive regulation of calcium ion transmembrane transport(GO:1904427)
0.2 0.7 GO:0048211 Golgi vesicle docking(GO:0048211)
0.2 1.2 GO:0032196 transposition(GO:0032196)
0.2 1.0 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.2 4.4 GO:0007520 myoblast fusion(GO:0007520)
0.2 13.6 GO:0060048 cardiac muscle contraction(GO:0060048)
0.2 1.2 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.2 3.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.2 4.0 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.2 11.4 GO:0008045 motor neuron axon guidance(GO:0008045)
0.2 19.4 GO:0017148 negative regulation of translation(GO:0017148)
0.2 1.8 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 2.5 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.2 4.5 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.2 0.9 GO:0034501 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.2 6.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.2 2.0 GO:0046548 retinal rod cell development(GO:0046548)
0.2 11.7 GO:0055123 digestive system development(GO:0055123)
0.2 29.9 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.2 14.9 GO:0006672 ceramide metabolic process(GO:0006672)
0.2 1.1 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.2 6.0 GO:0016925 protein sumoylation(GO:0016925)
0.2 1.3 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.2 1.9 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.2 1.4 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 2.2 GO:0021986 habenula development(GO:0021986)
0.2 3.4 GO:0021915 neural tube development(GO:0021915)
0.2 0.8 GO:0050435 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987) beta-amyloid metabolic process(GO:0050435)
0.2 8.2 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.2 0.4 GO:0021983 pituitary gland development(GO:0021983)
0.2 0.6 GO:0034629 cellular protein complex localization(GO:0034629)
0.2 1.7 GO:0003171 atrioventricular valve development(GO:0003171)
0.2 5.1 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.2 4.9 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)
0.2 2.3 GO:0009409 response to cold(GO:0009409)
0.2 0.6 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 4.6 GO:0043113 receptor clustering(GO:0043113)
0.2 2.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.2 1.7 GO:0006829 zinc II ion transport(GO:0006829)
0.2 11.7 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.2 2.7 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.2 0.9 GO:0016093 polyprenol metabolic process(GO:0016093)
0.2 3.0 GO:0048538 thymus development(GO:0048538)
0.2 0.9 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.2 4.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 1.9 GO:1901071 chitin metabolic process(GO:0006030) glucosamine-containing compound metabolic process(GO:1901071)
0.2 1.3 GO:0034063 stress granule assembly(GO:0034063)
0.2 3.7 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.2 1.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.2 0.6 GO:0089700 protein kinase D signaling(GO:0089700)
0.2 3.1 GO:0055088 lipid homeostasis(GO:0055088)
0.2 2.3 GO:0008406 gonad development(GO:0008406)
0.2 13.5 GO:0006413 translational initiation(GO:0006413)
0.2 0.8 GO:0032978 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.1 1.9 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 5.9 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.1 0.9 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 2.7 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 4.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 1.9 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 0.5 GO:0003262 endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262)
0.1 2.1 GO:0006665 sphingolipid metabolic process(GO:0006665)
0.1 0.5 GO:0051928 positive regulation of calcium ion transport(GO:0051928)
0.1 0.9 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 5.9 GO:0001894 tissue homeostasis(GO:0001894)
0.1 2.2 GO:0033334 fin morphogenesis(GO:0033334)
0.1 1.9 GO:0030217 T cell differentiation(GO:0030217)
0.1 0.2 GO:0034103 regulation of tissue remodeling(GO:0034103)
0.1 0.4 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.1 0.4 GO:0015874 norepinephrine transport(GO:0015874)
0.1 5.8 GO:0007043 cell-cell junction assembly(GO:0007043)
0.1 11.6 GO:0042254 ribosome biogenesis(GO:0042254)
0.1 0.4 GO:0072595 maintenance of protein localization in endoplasmic reticulum(GO:0035437) maintenance of protein localization in organelle(GO:0072595)
0.1 2.0 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 4.2 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 4.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 2.7 GO:0006937 regulation of muscle contraction(GO:0006937)
0.1 0.5 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 4.3 GO:0016575 histone deacetylation(GO:0016575)
0.1 0.6 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.7 GO:0043248 proteasome assembly(GO:0043248)
0.1 3.1 GO:0045332 phospholipid translocation(GO:0045332)
0.1 1.8 GO:0051028 mRNA transport(GO:0051028)
0.1 2.0 GO:0002573 myeloid leukocyte differentiation(GO:0002573)
0.1 1.7 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.1 1.5 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 1.1 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.1 2.6 GO:1903706 regulation of hemopoiesis(GO:1903706)
0.1 4.1 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.1 1.0 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 0.3 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 1.9 GO:1903844 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.1 1.2 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.1 0.4 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 1.2 GO:0048821 erythrocyte development(GO:0048821)
0.1 2.0 GO:0032456 endocytic recycling(GO:0032456)
0.1 1.5 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1 0.6 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 12.9 GO:0006412 translation(GO:0006412)
0.1 0.3 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.1 0.8 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.8 GO:0006094 gluconeogenesis(GO:0006094)
0.0 0.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.6 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 1.6 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 0.7 GO:0031647 regulation of protein stability(GO:0031647)
0.0 0.8 GO:0010675 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.0 0.5 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.6 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.2 GO:0016072 rRNA metabolic process(GO:0016072)
0.0 0.3 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 2.3 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.2 GO:0006868 glutamine transport(GO:0006868)
0.0 0.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
20.2 80.9 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
13.2 39.5 GO:0043218 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
11.9 35.7 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
7.8 148.1 GO:0030057 desmosome(GO:0030057)
7.7 92.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
5.3 15.9 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
5.0 25.2 GO:0097433 dense body(GO:0097433)
4.5 13.4 GO:0005948 acetolactate synthase complex(GO:0005948)
4.4 88.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
3.9 35.1 GO:0031526 brush border membrane(GO:0031526)
3.7 11.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
3.7 44.8 GO:0016328 lateral plasma membrane(GO:0016328)
3.7 22.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
3.6 14.3 GO:0019815 B cell receptor complex(GO:0019815)
3.3 409.6 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
3.2 16.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
3.0 23.9 GO:0042613 MHC class II protein complex(GO:0042613)
2.8 56.9 GO:0009925 basal plasma membrane(GO:0009925)
2.8 22.1 GO:0043020 NADPH oxidase complex(GO:0043020)
2.6 12.9 GO:0034362 low-density lipoprotein particle(GO:0034362)
2.3 13.9 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
2.3 16.0 GO:0000439 core TFIIH complex(GO:0000439)
2.2 15.3 GO:0005663 DNA replication factor C complex(GO:0005663)
2.2 60.5 GO:0005839 proteasome core complex(GO:0005839)
2.1 131.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
2.1 8.3 GO:0017177 glucosidase II complex(GO:0017177)
2.0 10.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
2.0 6.0 GO:0010369 chromocenter(GO:0010369)
2.0 9.9 GO:0005797 Golgi medial cisterna(GO:0005797)
2.0 21.7 GO:0014704 intercalated disc(GO:0014704)
1.9 3.8 GO:0031501 mannosyltransferase complex(GO:0031501)
1.9 9.3 GO:0032433 filopodium tip(GO:0032433)
1.8 25.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
1.8 19.7 GO:0045095 keratin filament(GO:0045095)
1.8 7.1 GO:0008537 proteasome activator complex(GO:0008537)
1.7 13.7 GO:0005614 interstitial matrix(GO:0005614)
1.7 142.0 GO:0005581 collagen trimer(GO:0005581)
1.6 8.1 GO:0070390 transcription export complex 2(GO:0070390)
1.6 6.4 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
1.5 29.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.3 32.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
1.2 20.0 GO:0005869 dynactin complex(GO:0005869)
1.2 11.2 GO:0071797 LUBAC complex(GO:0071797)
1.2 5.9 GO:0031258 lamellipodium membrane(GO:0031258)
1.2 51.2 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
1.2 4.6 GO:0044611 nuclear pore inner ring(GO:0044611)
1.1 3.4 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
1.1 4.6 GO:0043073 germ cell nucleus(GO:0043073)
1.1 4.4 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
1.1 51.7 GO:0022626 cytosolic ribosome(GO:0022626)
1.1 103.8 GO:0005795 Golgi stack(GO:0005795)
1.1 4.3 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
1.1 60.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
1.1 7.4 GO:0005826 actomyosin contractile ring(GO:0005826)
1.0 7.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
1.0 128.7 GO:0016459 myosin complex(GO:0016459)
1.0 93.9 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
1.0 3.0 GO:0098536 deuterosome(GO:0098536)
1.0 31.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
1.0 5.0 GO:0042824 MHC class I peptide loading complex(GO:0042824)
1.0 22.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
1.0 36.0 GO:0032587 ruffle membrane(GO:0032587)
1.0 4.8 GO:0031298 replication fork protection complex(GO:0031298)
0.9 4.7 GO:0071439 clathrin complex(GO:0071439)
0.9 7.5 GO:0000796 condensin complex(GO:0000796)
0.9 35.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.9 2.7 GO:0032998 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.9 4.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.9 19.6 GO:0030686 90S preribosome(GO:0030686)
0.8 16.1 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.8 93.7 GO:0016324 apical plasma membrane(GO:0016324)
0.8 2.5 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.8 6.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.8 3.1 GO:0070209 ASTRA complex(GO:0070209)
0.8 8.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.8 7.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.8 9.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.8 5.4 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.8 13.6 GO:0045178 basal part of cell(GO:0045178)
0.7 37.9 GO:0005811 lipid particle(GO:0005811)
0.7 5.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.7 5.1 GO:0030892 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.7 7.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.7 3.5 GO:1990923 PET complex(GO:1990923)
0.7 7.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.7 7.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.7 796.5 GO:0005615 extracellular space(GO:0005615)
0.6 18.1 GO:0000145 exocyst(GO:0000145)
0.6 8.8 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.6 12.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.6 7.4 GO:0002102 podosome(GO:0002102)
0.6 118.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.6 85.4 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.6 8.8 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.6 10.0 GO:0042555 MCM complex(GO:0042555)
0.5 2.7 GO:0030893 meiotic cohesin complex(GO:0030893)
0.5 4.3 GO:0032797 SMN complex(GO:0032797)
0.5 15.6 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.5 2.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.5 11.2 GO:0000421 autophagosome membrane(GO:0000421)
0.5 56.0 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.5 26.1 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.4 23.3 GO:0031901 early endosome membrane(GO:0031901)
0.4 2.6 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.4 3.0 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.4 2.6 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.4 1.7 GO:0001650 fibrillar center(GO:0001650)
0.4 6.1 GO:0070187 telosome(GO:0070187)
0.4 1.9 GO:1990023 mitotic spindle midzone(GO:1990023)
0.4 5.2 GO:0048179 activin receptor complex(GO:0048179)
0.4 2.6 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.4 10.6 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.4 37.1 GO:0005884 actin filament(GO:0005884)
0.4 1.4 GO:0031511 Mis6-Sim4 complex(GO:0031511)
0.4 7.0 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.3 2.4 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.3 12.9 GO:0016605 PML body(GO:0016605)
0.3 19.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.3 19.1 GO:0030027 lamellipodium(GO:0030027)
0.3 4.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.3 13.5 GO:0005643 nuclear pore(GO:0005643)
0.3 17.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.3 5.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.3 6.9 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.3 12.1 GO:0005861 troponin complex(GO:0005861)
0.3 3.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.3 0.8 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.3 15.4 GO:0005604 basement membrane(GO:0005604)
0.3 6.5 GO:0035861 site of double-strand break(GO:0035861)
0.3 47.0 GO:0015629 actin cytoskeleton(GO:0015629)
0.2 2.2 GO:0089701 U2AF(GO:0089701)
0.2 6.7 GO:0005657 replication fork(GO:0005657)
0.2 5.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 2.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.2 10.1 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.2 0.9 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.2 4.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.2 26.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.2 2.3 GO:0016580 Sin3 complex(GO:0016580)
0.2 8.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 1.5 GO:0030428 cell septum(GO:0030428)
0.2 17.0 GO:0044815 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.2 2.8 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.2 1.9 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2 0.7 GO:0071203 WASH complex(GO:0071203)
0.2 10.4 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.2 1.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.2 3.4 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 8.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.3 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.9 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 2.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 3.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 5.1 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 15.0 GO:0009986 cell surface(GO:0009986)
0.1 1.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 12.5 GO:0031012 extracellular matrix(GO:0031012)
0.1 3.1 GO:0030496 midbody(GO:0030496)
0.1 1.2 GO:0015030 Cajal body(GO:0015030)
0.1 3.5 GO:0030139 endocytic vesicle(GO:0030139)
0.1 1.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 2.0 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898) cytoplasmic side of membrane(GO:0098562)
0.1 7.8 GO:0005764 lysosome(GO:0005764)
0.1 2.5 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 39.1 GO:0005576 extracellular region(GO:0005576)
0.1 1.0 GO:0017119 Golgi transport complex(GO:0017119)
0.1 1.5 GO:0098844 dendritic spine head(GO:0044327) postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.1 2.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.4 GO:0005876 spindle microtubule(GO:0005876)
0.1 3.3 GO:0016592 mediator complex(GO:0016592)
0.1 19.9 GO:0005667 transcription factor complex(GO:0005667)
0.1 0.3 GO:0000814 ESCRT II complex(GO:0000814)
0.0 5.7 GO:0005840 ribosome(GO:0005840)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.3 GO:0070552 BRISC complex(GO:0070552)
0.0 0.4 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.7 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.5 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 3.1 GO:0000785 chromatin(GO:0000785)
0.0 0.9 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.0 1.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
25.2 75.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
14.8 44.3 GO:0034185 apolipoprotein binding(GO:0034185)
10.1 30.4 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174)
9.6 48.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
9.4 47.1 GO:0070644 vitamin D response element binding(GO:0070644)
9.3 74.0 GO:0015057 thrombin receptor activity(GO:0015057)
8.1 24.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
7.6 22.9 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
7.5 44.8 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
6.5 32.7 GO:0043394 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
6.1 24.3 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
6.0 30.0 GO:0038132 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
5.8 17.3 GO:0001729 ceramide kinase activity(GO:0001729)
5.7 56.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
5.1 15.3 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
5.0 25.2 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
5.0 64.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
4.8 14.4 GO:0004017 adenylate kinase activity(GO:0004017)
4.7 14.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
4.7 14.0 GO:1901612 cardiolipin binding(GO:1901612)
4.6 13.8 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
4.5 13.4 GO:0003984 acetolactate synthase activity(GO:0003984)
4.4 8.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
4.4 47.9 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
4.3 38.7 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
4.3 90.2 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
4.1 57.8 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
4.1 12.4 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765) inositol trisphosphate kinase activity(GO:0051766)
4.1 24.6 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
3.8 11.5 GO:0016019 peptidoglycan receptor activity(GO:0016019)
3.7 14.8 GO:0003796 lysozyme activity(GO:0003796)
3.7 44.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
3.7 18.4 GO:0098639 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
3.5 17.7 GO:0039706 co-receptor binding(GO:0039706)
3.5 13.8 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
3.4 13.5 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
3.4 10.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
3.2 28.8 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
3.1 12.6 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
3.1 28.0 GO:0005113 patched binding(GO:0005113)
3.1 15.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
3.0 32.9 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
3.0 23.9 GO:0070008 serine-type exopeptidase activity(GO:0070008)
2.9 29.1 GO:0050700 CARD domain binding(GO:0050700)
2.9 5.8 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
2.8 11.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
2.8 8.4 GO:0046923 ER retention sequence binding(GO:0046923)
2.8 11.2 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
2.7 16.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
2.7 314.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
2.7 13.5 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
2.7 13.4 GO:0008097 5S rRNA binding(GO:0008097)
2.6 23.8 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
2.6 39.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
2.6 7.8 GO:0004301 epoxide hydrolase activity(GO:0004301)
2.6 31.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
2.6 30.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
2.5 22.6 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
2.5 17.4 GO:1903924 estradiol binding(GO:1903924)
2.5 9.9 GO:0072571 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
2.4 19.0 GO:0008515 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
2.3 7.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
2.3 23.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
2.3 71.6 GO:0004364 glutathione transferase activity(GO:0004364)
2.3 18.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
2.3 280.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
2.2 15.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
2.2 36.7 GO:0019894 kinesin binding(GO:0019894)
2.1 12.9 GO:0070325 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
2.1 19.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
2.1 10.7 GO:0009374 biotin binding(GO:0009374)
2.1 14.9 GO:0004974 leukotriene receptor activity(GO:0004974)
2.0 23.7 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
1.9 36.9 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.9 7.7 GO:0008887 glycerate kinase activity(GO:0008887)
1.9 48.1 GO:0035591 signaling adaptor activity(GO:0035591)
1.8 3.7 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
1.8 20.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
1.8 34.0 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
1.7 7.0 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
1.7 10.4 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
1.7 6.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.7 49.8 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
1.7 5.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.7 10.3 GO:0017040 ceramidase activity(GO:0017040)
1.7 389.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
1.7 8.5 GO:0019215 intermediate filament binding(GO:0019215)
1.7 13.6 GO:0036122 BMP binding(GO:0036122)
1.7 5.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
1.7 6.7 GO:0034511 U3 snoRNA binding(GO:0034511)
1.7 16.8 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
1.7 5.0 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
1.7 6.6 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
1.7 5.0 GO:0046978 TAP1 binding(GO:0046978)
1.6 6.5 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
1.6 9.6 GO:0005412 glucose:sodium symporter activity(GO:0005412)
1.6 22.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
1.6 7.9 GO:0051903 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
1.6 70.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
1.6 15.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
1.6 4.7 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
1.5 10.8 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
1.5 7.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
1.5 16.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
1.5 13.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
1.5 16.2 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
1.5 7.4 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
1.5 7.4 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
1.5 4.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
1.5 4.4 GO:0016748 succinyltransferase activity(GO:0016748)
1.5 13.1 GO:0048039 ubiquinone binding(GO:0048039)
1.5 11.7 GO:0002020 protease binding(GO:0002020)
1.4 15.9 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
1.4 14.5 GO:0016936 galactoside binding(GO:0016936)
1.4 5.7 GO:0070052 collagen V binding(GO:0070052)
1.4 28.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
1.4 15.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
1.4 9.9 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
1.4 15.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.4 5.5 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
1.4 11.0 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
1.4 12.4 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
1.4 4.1 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
1.4 14.9 GO:0004046 aminoacylase activity(GO:0004046)
1.3 7.9 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
1.3 11.6 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
1.3 32.2 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
1.3 6.4 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
1.3 12.8 GO:0005522 profilin binding(GO:0005522)
1.3 21.5 GO:0008649 rRNA methyltransferase activity(GO:0008649)
1.2 17.5 GO:0008327 methyl-CpG binding(GO:0008327)
1.2 34.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
1.2 11.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
1.2 19.9 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
1.2 4.9 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
1.2 3.7 GO:0031752 D5 dopamine receptor binding(GO:0031752)
1.2 12.2 GO:0070700 BMP receptor binding(GO:0070700)
1.2 8.4 GO:0004962 endothelin receptor activity(GO:0004962)
1.2 7.1 GO:0061133 endopeptidase activator activity(GO:0061133)
1.2 5.8 GO:0003993 acid phosphatase activity(GO:0003993)
1.2 64.1 GO:0000146 microfilament motor activity(GO:0000146)
1.2 16.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
1.2 3.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
1.1 9.1 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
1.1 4.5 GO:0004925 prolactin receptor activity(GO:0004925)
1.1 5.5 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
1.1 4.4 GO:0005119 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
1.1 15.3 GO:0032051 clathrin light chain binding(GO:0032051)
1.1 10.7 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
1.0 32.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.0 26.8 GO:0042043 neurexin family protein binding(GO:0042043)
1.0 20.6 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
1.0 2.1 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
1.0 3.1 GO:0051185 coenzyme transporter activity(GO:0051185)
1.0 17.4 GO:0015923 mannosidase activity(GO:0015923)
1.0 5.1 GO:0008026 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
1.0 9.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
1.0 8.0 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
1.0 4.9 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
1.0 15.7 GO:0016018 cyclosporin A binding(GO:0016018)
1.0 10.7 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
1.0 48.6 GO:0043022 ribosome binding(GO:0043022)
1.0 3.8 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.9 2.8 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.9 5.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.9 75.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.9 1.9 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.9 18.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.9 5.5 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.9 6.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.9 99.6 GO:0004896 cytokine receptor activity(GO:0004896)
0.9 2.7 GO:0019763 immunoglobulin receptor activity(GO:0019763) IgE receptor activity(GO:0019767)
0.9 7.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.9 4.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.9 12.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.9 4.5 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.9 10.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.9 10.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.9 11.6 GO:0016783 sulfurtransferase activity(GO:0016783)
0.9 8.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.9 4.4 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.9 38.6 GO:0005178 integrin binding(GO:0005178)
0.9 2.6 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.8 27.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.8 6.6 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.8 18.8 GO:0005518 collagen binding(GO:0005518)
0.8 153.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.8 2.4 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.8 17.6 GO:0005523 tropomyosin binding(GO:0005523)
0.8 16.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.8 14.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.8 5.6 GO:0034632 retinol transporter activity(GO:0034632)
0.8 7.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.8 7.9 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.8 27.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.8 9.3 GO:0031720 haptoglobin binding(GO:0031720)
0.8 17.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.8 16.8 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.8 20.5 GO:0042805 actinin binding(GO:0042805)
0.8 16.7 GO:0004065 arylsulfatase activity(GO:0004065)
0.8 5.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.7 91.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.7 17.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.7 20.0 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.7 3.4 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.7 11.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.7 4.6 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.7 4.6 GO:0019955 cytokine binding(GO:0019955)
0.6 2.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.6 20.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.6 3.7 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.6 6.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.6 2.5 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.6 7.4 GO:0048038 quinone binding(GO:0048038)
0.6 38.9 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.6 3.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.6 6.5 GO:0004623 phospholipase A2 activity(GO:0004623)
0.6 1.8 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.6 14.4 GO:0005112 Notch binding(GO:0005112)
0.6 6.9 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.6 29.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.6 10.0 GO:0035497 cAMP response element binding(GO:0035497)
0.6 1.7 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.6 5.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.5 92.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.5 17.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.5 5.4 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.5 1.6 GO:0016496 substance P receptor activity(GO:0016496)
0.5 78.4 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.5 3.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.5 9.2 GO:0048185 activin binding(GO:0048185)
0.5 1.5 GO:0015295 solute:proton symporter activity(GO:0015295)
0.5 17.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.5 2.5 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.5 7.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.5 3.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.5 2.0 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.5 1.5 GO:0072545 tyrosine binding(GO:0072545)
0.5 13.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.5 1.0 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.5 9.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.5 9.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.5 13.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.5 12.6 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.5 15.8 GO:0004180 carboxypeptidase activity(GO:0004180)
0.5 5.1 GO:0035804 structural constituent of egg coat(GO:0035804)
0.4 2.7 GO:0032190 acrosin binding(GO:0032190)
0.4 28.7 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.4 54.1 GO:0042803 protein homodimerization activity(GO:0042803)
0.4 3.5 GO:0034584 piRNA binding(GO:0034584)
0.4 1.3 GO:0003999 adenine phosphoribosyltransferase activity(GO:0003999)
0.4 5.6 GO:0030515 snoRNA binding(GO:0030515)
0.4 4.2 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.4 5.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.4 112.6 GO:0051015 actin filament binding(GO:0051015)
0.4 3.6 GO:0019843 rRNA binding(GO:0019843)
0.4 1.2 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.4 16.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.4 53.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.4 3.0 GO:0015232 heme transporter activity(GO:0015232)
0.4 5.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.4 7.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.4 3.3 GO:0004359 glutaminase activity(GO:0004359)
0.4 1.4 GO:0001096 RNA polymerase II basal transcription factor binding(GO:0001091) TFIIF-class transcription factor binding(GO:0001096)
0.4 2.5 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.4 7.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.4 3.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.4 7.0 GO:0070411 I-SMAD binding(GO:0070411)
0.4 7.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.3 2.4 GO:0070698 type I activin receptor binding(GO:0070698)
0.3 2.8 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.3 18.4 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.3 13.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.3 2.3 GO:0071916 oligopeptide transporter activity(GO:0015198) oligopeptide transmembrane transporter activity(GO:0035673) dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.3 16.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 21.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.3 2.9 GO:0008199 ferric iron binding(GO:0008199)
0.3 1.3 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.3 10.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.3 1.9 GO:0043531 ADP binding(GO:0043531)
0.3 2.1 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.3 0.9 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.3 23.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.3 2.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.3 1.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.3 1.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.3 8.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.3 1.6 GO:0030331 estrogen receptor binding(GO:0030331) retinoic acid receptor binding(GO:0042974)
0.3 80.3 GO:0005198 structural molecule activity(GO:0005198)
0.3 5.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.3 1.3 GO:0060182 apelin receptor activity(GO:0060182)
0.2 20.1 GO:0042802 identical protein binding(GO:0042802)
0.2 6.5 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.2 1.9 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.2 0.7 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 2.6 GO:0048256 flap endonuclease activity(GO:0048256)
0.2 5.7 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.2 6.1 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.2 0.9 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.2 6.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 4.7 GO:0004875 complement receptor activity(GO:0004875)
0.2 46.4 GO:0046983 protein dimerization activity(GO:0046983)
0.2 2.0 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.2 17.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 10.5 GO:0008201 heparin binding(GO:0008201)
0.2 3.0 GO:0046527 glucosyltransferase activity(GO:0046527)
0.2 1.3 GO:0015616 DNA translocase activity(GO:0015616)
0.2 2.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 334.6 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.2 0.8 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.2 3.5 GO:0045159 myosin II binding(GO:0045159)
0.2 2.0 GO:0005042 netrin receptor activity(GO:0005042)
0.2 1.0 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.2 0.6 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.2 6.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.2 3.1 GO:0050811 GABA receptor binding(GO:0050811)
0.2 2.5 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.2 3.3 GO:0003823 antigen binding(GO:0003823)
0.2 0.6 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.2 2.4 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.2 3.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 0.9 GO:0030060 malate dehydrogenase activity(GO:0016615) L-malate dehydrogenase activity(GO:0030060)
0.2 3.9 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.2 1.9 GO:0070628 proteasome binding(GO:0070628)
0.2 3.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 11.2 GO:0045499 chemorepellent activity(GO:0045499)
0.2 9.8 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.2 1.9 GO:0004568 chitinase activity(GO:0004568)
0.2 7.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 3.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.2 1.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738)
0.2 1.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 2.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 1.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 4.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 1.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 3.4 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.2 2.0 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.2 3.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.2 1.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 7.5 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 0.6 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADPH binding(GO:0070402) NADH binding(GO:0070404)
0.1 0.5 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.1 2.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 26.5 GO:0030246 carbohydrate binding(GO:0030246)
0.1 97.0 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.1 0.5 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 0.6 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.7 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.8 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 0.8 GO:0015250 water channel activity(GO:0015250)
0.1 3.1 GO:0004175 endopeptidase activity(GO:0004175)
0.1 7.1 GO:0003678 DNA helicase activity(GO:0003678)
0.1 7.8 GO:0003724 RNA helicase activity(GO:0003724)
0.1 1.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 36.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 0.3 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 13.1 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.1 18.8 GO:0019901 protein kinase binding(GO:0019901)
0.1 0.6 GO:0044389 ubiquitin-like protein ligase binding(GO:0044389)
0.1 6.9 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.6 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.8 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 1.5 GO:0002039 p53 binding(GO:0002039)
0.1 1.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 2.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 0.8 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.3 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.1 5.5 GO:0003713 transcription coactivator activity(GO:0003713)
0.1 1.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 2.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 1.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.5 GO:0032977 membrane insertase activity(GO:0032977)
0.1 44.4 GO:0008270 zinc ion binding(GO:0008270)
0.1 0.6 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.1 1.7 GO:0004620 phospholipase activity(GO:0004620)
0.1 0.3 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.2 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.1 3.3 GO:0003690 double-stranded DNA binding(GO:0003690)
0.1 1.0 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 0.7 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 5.3 GO:0042393 histone binding(GO:0042393)
0.0 0.3 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.8 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 5.3 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 1.0 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 3.4 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.3 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.6 GO:0008233 peptidase activity(GO:0008233)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
11.6 11.6 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
5.6 33.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
5.4 139.9 PID NECTIN PATHWAY Nectin adhesion pathway
3.5 147.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
3.0 29.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
2.3 25.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
2.2 58.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
2.0 8.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
1.7 57.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
1.7 15.0 PID S1P S1P3 PATHWAY S1P3 pathway
1.6 31.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
1.6 6.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
1.3 22.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
1.3 29.8 PID WNT SIGNALING PATHWAY Wnt signaling network
1.3 26.5 PID ENDOTHELIN PATHWAY Endothelins
1.3 53.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
1.2 10.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
1.2 7.4 PID IL5 PATHWAY IL5-mediated signaling events
1.2 46.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
1.2 12.2 PID EPHB FWD PATHWAY EPHB forward signaling
1.2 9.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
1.2 13.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
1.1 3.4 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
1.1 67.0 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
1.1 14.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
1.1 11.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
1.1 8.9 ST G ALPHA S PATHWAY G alpha s Pathway
1.1 13.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
1.1 16.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
1.0 3.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
1.0 21.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.9 13.2 PID ALK2 PATHWAY ALK2 signaling events
0.9 37.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.9 22.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.8 5.9 PID TRAIL PATHWAY TRAIL signaling pathway
0.8 19.8 PID BCR 5PATHWAY BCR signaling pathway
0.8 4.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.7 10.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.7 3.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.7 2.0 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.6 5.2 NABA COLLAGENS Genes encoding collagen proteins
0.6 29.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.6 23.6 PID ATR PATHWAY ATR signaling pathway
0.6 7.2 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.6 6.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.6 4.4 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.5 6.5 PID ARF6 PATHWAY Arf6 signaling events
0.5 27.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.5 7.9 ST GA13 PATHWAY G alpha 13 Pathway
0.5 6.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.4 7.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.4 2.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.4 17.1 PID CMYB PATHWAY C-MYB transcription factor network
0.4 6.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.4 6.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.3 11.3 PID P53 REGULATION PATHWAY p53 pathway
0.3 3.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.3 4.8 PID IL1 PATHWAY IL1-mediated signaling events
0.3 4.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.3 42.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3 40.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.3 8.9 PID AURORA B PATHWAY Aurora B signaling
0.3 12.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.3 2.3 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.2 8.6 PID E2F PATHWAY E2F transcription factor network
0.2 3.0 PID TNF PATHWAY TNF receptor signaling pathway
0.2 1.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.2 5.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.2 2.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 2.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.2 1.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 20.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 2.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 2.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 3.2 PID P73PATHWAY p73 transcription factor network
0.1 0.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 1.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 0.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.1 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID FANCONI PATHWAY Fanconi anemia pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
20.1 60.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
7.7 68.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
4.8 33.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
4.4 21.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
3.5 28.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
3.4 10.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
2.9 142.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
2.9 54.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
2.8 39.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
2.2 17.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
1.8 52.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
1.7 24.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
1.7 188.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
1.6 16.4 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
1.5 25.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
1.4 12.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
1.4 28.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.4 10.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
1.3 28.8 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
1.3 16.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
1.3 16.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
1.2 7.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
1.2 9.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
1.1 45.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
1.1 10.0 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
1.1 22.9 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
1.1 11.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
1.1 14.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
1.0 8.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
1.0 2.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
1.0 6.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
1.0 26.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
1.0 29.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
1.0 11.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
1.0 11.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.9 11.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.9 5.6 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.9 12.9 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.9 15.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.9 28.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.9 100.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.9 25.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.9 28.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.9 20.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.9 10.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.8 5.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.8 7.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.8 12.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.8 9.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.8 10.7 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.8 8.6 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.8 18.6 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.8 13.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.7 2.2 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.7 11.8 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.6 3.9 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.6 14.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.6 30.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.6 6.7 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.6 14.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.6 10.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.6 3.4 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.6 8.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.6 25.6 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.6 43.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.5 3.8 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.5 6.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.5 2.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.5 43.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.5 5.2 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.5 5.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.4 8.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.4 6.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.4 4.8 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.4 3.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.4 3.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.4 2.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.4 16.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.4 16.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.4 14.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.4 8.1 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.4 24.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.4 8.1 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.4 4.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.4 3.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.4 1.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3 2.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.3 3.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 7.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 4.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.3 7.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.3 0.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 1.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 5.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2 1.5 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.2 1.4 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.2 2.6 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.2 12.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 10.7 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.2 5.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2 2.5 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.2 1.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.2 1.7 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.2 2.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 4.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 1.3 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.2 2.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.6 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 1.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 0.7 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 1.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.9 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 2.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 0.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 0.8 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 2.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 0.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 6.0 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.2 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism