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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish
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Results for znf384l
Z-value: 1.32
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Transcription factors associated with znf384l
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| znf384l | dr11_v1_chr19_-_6983002_6983002 | -0.20 | 5.6e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_+_1838164 Show fit | 13.46 |
ENSDART00000006013
|
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 5 |
|
| chr16_-_23346095 Show fit | 12.61 |
ENSDART00000160546
|
si:dkey-247k7.2 |
|
| chr16_+_35924188 Show fit | 11.75 |
ENSDART00000165847
|
SH3 domain containing 21 |
|
| chr22_-_15593824 Show fit | 10.16 |
ENSDART00000123125
|
tropomyosin 4a |
|
| chr16_-_21038015 Show fit | 10.07 |
ENSDART00000059239
|
sorting nexin 10b |
|
| chr25_+_8356707 Show fit | 9.25 |
ENSDART00000153708
|
mucin 5.1, oligomeric mucus/gel-forming |
|
| chr17_-_8862424 Show fit | 9.19 |
ENSDART00000064633
|
NK-lysin tandem duplicate 4 |
|
| chr2_-_20923864 Show fit | 8.78 |
ENSDART00000006870
|
prostaglandin-endoperoxide synthase 2a |
|
| chr7_-_31441420 Show fit | 8.70 |
ENSDART00000075398
|
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
|
| chr12_-_4249000 Show fit | 8.42 |
ENSDART00000059298
|
zgc:92313 |
Network of associatons between targets according to the STRING database.
First level regulatory network of znf384l
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 20.8 | GO:0042742 | defense response to bacterium(GO:0042742) |
| 0.9 | 18.0 | GO:0036376 | cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436) |
| 0.2 | 14.8 | GO:0007229 | integrin-mediated signaling pathway(GO:0007229) |
| 1.4 | 14.4 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
| 0.0 | 13.4 | GO:0006955 | immune response(GO:0006955) |
| 0.4 | 10.2 | GO:0055003 | cardiac myofibril assembly(GO:0055003) |
| 0.1 | 10.0 | GO:0030048 | actin filament-based movement(GO:0030048) |
| 0.1 | 10.0 | GO:0031101 | fin regeneration(GO:0031101) |
| 0.2 | 9.7 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.1 | 9.5 | GO:0007160 | cell-matrix adhesion(GO:0007160) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 32.1 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 28.0 | GO:0005615 | extracellular space(GO:0005615) |
| 0.2 | 16.0 | GO:0030018 | Z disc(GO:0030018) |
| 0.2 | 15.1 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 15.1 | GO:0070160 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 0.0 | 13.3 | GO:0005764 | lysosome(GO:0005764) |
| 0.1 | 10.5 | GO:0005884 | actin filament(GO:0005884) |
| 0.1 | 10.1 | GO:0010008 | endosome membrane(GO:0010008) |
| 0.2 | 9.6 | GO:0008305 | integrin complex(GO:0008305) |
| 0.5 | 8.9 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 15.8 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
| 0.7 | 14.4 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 11.5 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.0 | 11.4 | GO:0003779 | actin binding(GO:0003779) |
| 0.1 | 10.9 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
| 0.0 | 10.5 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.2 | 10.0 | GO:0000146 | microfilament motor activity(GO:0000146) |
| 0.0 | 9.8 | GO:0005525 | GTP binding(GO:0005525) |
| 0.1 | 9.3 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 2.2 | 8.8 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 11.3 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 9.8 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.2 | 7.4 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.1 | 5.2 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.1 | 5.0 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.2 | 4.9 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 4.9 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.1 | 4.7 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.2 | 4.3 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.1 | 4.1 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.4 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.3 | 7.5 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.1 | 6.7 | REACTOME PI3K EVENTS IN ERBB2 SIGNALING | Genes involved in PI3K events in ERBB2 signaling |
| 0.1 | 6.6 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 5.6 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.4 | 5.3 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.4 | 4.9 | REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
| 0.3 | 4.9 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.3 | 4.4 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.3 | 4.1 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |