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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for znf711

Z-value: 1.37

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Transcription factors associated with znf711

Gene Symbol Gene ID Gene Info
znf711
ENSDARG00000071868 Danio rerio zinc finger protein 711 (znf711), transcript variant 1, mRNA.
znf711
ENSDARG00000111963 zinc finger protein 711

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
znf711dr11_v1_chr14_-_12020653_12020653-0.151.5e-01Click!

Activity profile of znf711 motif

Sorted Z-values of znf711 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_23645810 24.07 ENSDART00000168845
ckmb
creatine kinase, muscle b
chr5_+_51594209 22.74 ENSDART00000164668
ENSDART00000058403
ENSDART00000055857
ckmt2b
creatine kinase, mitochondrial 2b (sarcomeric)
chr23_-_10175898 19.88 ENSDART00000146185
krt5
keratin 5
chr13_+_22480496 17.90 ENSDART00000136863
ENSDART00000131870
ENSDART00000078720
ENSDART00000078740
ENSDART00000139218
ldb3a
LIM domain binding 3a
chr3_+_32526799 12.86 ENSDART00000185755
si:ch73-367p23.2
si:ch73-367p23.2
chr3_+_23221047 12.32 ENSDART00000009393
col1a1a
collagen, type I, alpha 1a
chr13_+_24280380 11.45 ENSDART00000184115
acta1b
actin, alpha 1b, skeletal muscle
chr7_+_7048245 10.92 ENSDART00000001649
actn3b
actinin alpha 3b
chr8_-_1051438 10.89 ENSDART00000067093
ENSDART00000170737
smyd1b
SET and MYND domain containing 1b
chr13_+_22480857 10.81 ENSDART00000078721
ENSDART00000044719
ENSDART00000130957
ENSDART00000078757
ENSDART00000130424
ENSDART00000078747
ldb3a
LIM domain binding 3a
chr13_+_22479988 10.00 ENSDART00000188182
ENSDART00000192972
ENSDART00000178372
ldb3a
LIM domain binding 3a
chr17_-_15546862 9.99 ENSDART00000091021
col10a1a
collagen, type X, alpha 1a
chr7_+_29952719 9.35 ENSDART00000173737
tpma
alpha-tropomyosin
chr17_-_10025234 7.70 ENSDART00000008355
cfl2
cofilin 2 (muscle)
chr23_-_10177442 7.56 ENSDART00000144280
ENSDART00000129044
krt5
keratin 5
chr11_-_55224 7.21 ENSDART00000159169
col2a1b
collagen, type II, alpha 1b
chr9_-_33107237 7.20 ENSDART00000013918
casq2
calsequestrin 2
chr5_-_72390259 6.33 ENSDART00000172302
wbp1
WW domain binding protein 1
chr3_-_43770876 6.18 ENSDART00000160162
zgc:92162
zgc:92162
chr23_+_13814978 6.06 ENSDART00000090864
lmod3
leiomodin 3 (fetal)
chr19_+_31183495 5.99 ENSDART00000088618
meox2b
mesenchyme homeobox 2b
chr19_+_43119698 5.98 ENSDART00000167847
ENSDART00000186962
ENSDART00000187305
eef1a1l1
eukaryotic translation elongation factor 1 alpha 1, like 1
chr7_+_22747915 5.94 ENSDART00000173609
fxr2
fragile X mental retardation, autosomal homolog 2
chr11_-_22599584 5.93 ENSDART00000014062
myog
myogenin
chr7_+_22543963 5.92 ENSDART00000101528
chrnb1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr2_+_25245083 5.79 ENSDART00000189649
ENSDART00000139080
ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr11_+_11504014 5.69 ENSDART00000104264
ENSDART00000134806
ENSDART00000132291
zgc:171226
zgc:171226
chr18_-_50839033 5.67 ENSDART00000169773
ddb1
damage-specific DNA binding protein 1
chr11_-_3860534 5.27 ENSDART00000082425
gata2a
GATA binding protein 2a
chr6_+_28877306 5.17 ENSDART00000065137
ENSDART00000123189
ENSDART00000065135
ENSDART00000181512
ENSDART00000130799
tp63
tumor protein p63
chr25_-_26736088 5.17 ENSDART00000067114
fbxl22
F-box and leucine-rich repeat protein 22
chr7_-_35432901 5.13 ENSDART00000026712
mmp2
matrix metallopeptidase 2
chr5_-_47727819 5.07 ENSDART00000165249
cox7c
cytochrome c oxidase, subunit VIIc
chr24_+_42074143 5.02 ENSDART00000170514
top1mt
DNA topoisomerase I mitochondrial
chr20_+_26538137 4.90 ENSDART00000045397
stx11b.1
syntaxin 11b, tandem duplicate 1
chr15_-_34567370 4.77 ENSDART00000099793
sostdc1a
sclerostin domain containing 1a
chr5_-_1963498 4.67 ENSDART00000073462
rplp0
ribosomal protein, large, P0
chr7_-_48667056 4.66 ENSDART00000006378
cdkn1ca
cyclin-dependent kinase inhibitor 1Ca
chr24_+_25471196 4.42 ENSDART00000066625
smpx
small muscle protein, X-linked
chr9_-_105135 4.27 ENSDART00000180126
FQ377903.3

chr16_-_24194587 4.17 ENSDART00000181520
rps19
ribosomal protein S19
chr13_+_32148338 4.06 ENSDART00000188591
osr1
odd-skipped related transciption factor 1
chr2_+_5371492 4.05 ENSDART00000139762
si:ch1073-184j22.1
si:ch1073-184j22.1
chr6_-_10835849 4.00 ENSDART00000005903
ENSDART00000135065
atp5mc3b
ATP synthase membrane subunit c locus 3b
chr3_-_5644028 3.92 ENSDART00000019957
ddx39ab
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Ab
chr16_-_33817828 3.80 ENSDART00000188395
rspo1
R-spondin 1
chr6_-_15096556 3.75 ENSDART00000185327
fhl2b
four and a half LIM domains 2b
chr19_+_48018802 3.74 ENSDART00000161339
ENSDART00000166978
UBE2M
si:ch1073-205c8.3
chr3_-_29925482 3.70 ENSDART00000151525
grna
granulin a
chr23_+_22819971 3.58 ENSDART00000111345
rerea
arginine-glutamic acid dipeptide (RE) repeats a
chr7_-_52531252 3.58 ENSDART00000174369
tcf12
transcription factor 12
chr15_-_35960250 3.44 ENSDART00000186765
col4a4
collagen, type IV, alpha 4
chr1_+_8508753 3.43 ENSDART00000091683
alkbh5
alkB homolog 5, RNA demethylase
chr10_-_38243579 3.37 ENSDART00000150159
usp25
ubiquitin specific peptidase 25
chr20_+_1329509 3.37 ENSDART00000017791
ENSDART00000136669
tab2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr9_-_34260214 3.36 ENSDART00000012385
me3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr7_-_51639699 3.31 ENSDART00000128917
rps4x
ribosomal protein S4, X-linked
chr16_+_31921812 3.30 ENSDART00000176928
ENSDART00000193733
rps9
ribosomal protein S9
chr16_-_24195252 3.26 ENSDART00000136205
ENSDART00000048599
ENSDART00000161547
rps19
ribosomal protein S19
chr10_+_26669177 3.22 ENSDART00000143402
si:ch73-52f15.5
si:ch73-52f15.5
chr25_+_3099073 3.15 ENSDART00000022506
rab3il1
RAB3A interacting protein (rabin3)-like 1
chr1_-_54972170 3.12 ENSDART00000150548
ENSDART00000038330
khsrp
KH-type splicing regulatory protein
chr15_-_36249087 3.04 ENSDART00000157190
ostn
osteocrin
chr9_+_33145522 3.03 ENSDART00000005879
atp5po
ATP synthase peripheral stalk subunit OSCP
chr21_-_45871866 2.93 ENSDART00000161716
larp1
La ribonucleoprotein domain family, member 1
chr8_+_25733872 2.89 ENSDART00000156340
si:ch211-167b20.8
si:ch211-167b20.8
chr1_-_54971968 2.87 ENSDART00000140016
khsrp
KH-type splicing regulatory protein
chr8_+_26372115 2.86 ENSDART00000053460
nat6
N-acetyltransferase 6
chr13_+_21870269 2.82 ENSDART00000144612
zswim8
zinc finger, SWIM-type containing 8
chr20_+_33981946 2.76 ENSDART00000131775
si:dkey-51e6.1
si:dkey-51e6.1
chr16_+_27345383 2.72 ENSDART00000078250
ENSDART00000162857
nr4a3
nuclear receptor subfamily 4, group A, member 3
chr5_+_45000597 2.72 ENSDART00000051146
dmrt3a
doublesex and mab-3 related transcription factor 3a
chr5_-_4418555 2.70 ENSDART00000170158
apooa
apolipoprotein O, a
chr6_+_58832323 2.69 ENSDART00000042595
dctn2
dynactin 2 (p50)
chr14_-_52408307 2.68 ENSDART00000167045
ENSDART00000162719
ENSDART00000160293
polr2b
polymerase (RNA) II (DNA directed) polypeptide B
chr3_+_60957512 2.64 ENSDART00000044096
helz
helicase with zinc finger
chr5_-_18007077 2.64 ENSDART00000129878
zdhhc8b
zinc finger, DHHC-type containing 8b
chr23_-_3758637 2.63 ENSDART00000131536
ENSDART00000139408
ENSDART00000137826
hmga1a
high mobility group AT-hook 1a
chr7_-_18508815 2.60 ENSDART00000173539
rgs12a
regulator of G protein signaling 12a
chr19_-_48019366 2.57 ENSDART00000169429
si:ch1073-205c8.5
si:ch1073-205c8.5
chr7_+_40081630 2.56 ENSDART00000173559
zgc:112356
zgc:112356
chr12_+_22680115 2.55 ENSDART00000152879
ablim2
actin binding LIM protein family, member 2
chr23_+_34047413 2.53 ENSDART00000143933
ENSDART00000123925
ENSDART00000176139
chchd6a
coiled-coil-helix-coiled-coil-helix domain containing 6a
chr22_-_817479 2.50 ENSDART00000123487
zgc:153675
zgc:153675
chr19_-_81851 2.48 ENSDART00000172319
hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr5_-_15851953 2.47 ENSDART00000173101
si:dkey-1k23.3
si:dkey-1k23.3
chr21_+_11969603 2.45 ENSDART00000142247
ENSDART00000140652
mlnl
motilin-like
chr20_+_19176959 2.39 ENSDART00000163276
ENSDART00000020099
blk
BLK proto-oncogene, Src family tyrosine kinase
chr23_-_20010579 2.36 ENSDART00000089999
b4galt3
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr19_-_7110617 2.35 ENSDART00000104838
psmb8a
proteasome subunit beta 8A
chr9_+_21407987 2.34 ENSDART00000145627
gja3
gap junction protein, alpha 3
chr20_+_46492175 2.33 ENSDART00000060695
zc3h14
zinc finger CCCH-type containing 14
chr9_-_29036263 2.31 ENSDART00000160393
tmem177
transmembrane protein 177
chr14_+_38849432 2.31 ENSDART00000052511
hnrnpa0l
heterogeneous nuclear ribonucleoprotein A0, like
chr13_-_23007813 2.31 ENSDART00000057638
hk1
hexokinase 1
chr6_-_54107269 2.31 ENSDART00000190017
hyal2a
hyaluronoglucosaminidase 2a
chr3_+_23752150 2.30 ENSDART00000146636
hoxb2a
homeobox B2a
chr5_-_29238889 2.29 ENSDART00000143098
si:dkey-61l1.4
si:dkey-61l1.4
chr13_-_44738574 2.29 ENSDART00000074761
zfand3
zinc finger, AN1-type domain 3
chr21_-_36948 2.27 ENSDART00000181230
JMY
junction mediating and regulatory protein, p53 cofactor
chr11_-_127785 2.22 ENSDART00000162658
ARFGAP1
ADP ribosylation factor GTPase activating protein 1
chr3_+_43086548 2.21 ENSDART00000163579
si:dkey-43p13.5
si:dkey-43p13.5
chr19_+_12237945 2.15 ENSDART00000190034
grhl2b
grainyhead-like transcription factor 2b
chr1_+_41466011 2.15 ENSDART00000135280
paip2b
poly(A) binding protein interacting protein 2B
chr9_+_8898835 2.11 ENSDART00000147820
naxd
NAD(P)HX dehydratase
chr2_-_48255843 2.10 ENSDART00000056277
gigyf2
GRB10 interacting GYF protein 2
chr16_-_26676685 2.07 ENSDART00000103431
esrp1
epithelial splicing regulatory protein 1
chr19_-_47832853 2.07 ENSDART00000170988
ago4
argonaute RISC catalytic component 4
chr22_+_14836291 2.07 ENSDART00000122740
gtpbp1l
GTP binding protein 1, like
chr3_+_23742868 2.06 ENSDART00000153512
hoxb3a
homeobox B3a
chr5_+_13326765 2.04 ENSDART00000090851
ydjc
YdjC chitooligosaccharide deacetylase homolog
chr7_+_52811291 2.04 ENSDART00000192900
CT030160.1

chr5_+_20437124 2.03 ENSDART00000159001
tmem119a
transmembrane protein 119a
chr21_-_43428040 2.02 ENSDART00000148325
stk26
serine/threonine protein kinase 26
chr14_-_24001825 2.00 ENSDART00000130704
il4
interleukin 4
chr4_-_9557186 1.96 ENSDART00000150569
shank3b
SH3 and multiple ankyrin repeat domains 3b
chr20_-_26537171 1.96 ENSDART00000061926
stx11b.2
syntaxin 11b, tandem duplicate 2
chr3_-_40301467 1.95 ENSDART00000055186
atp5mf
ATP synthase membrane subunit f
chr12_-_7824291 1.94 ENSDART00000148673
ENSDART00000149453
ank3b
ankyrin 3b
chr10_+_26612321 1.93 ENSDART00000134322
fhl1b
four and a half LIM domains 1b
chr17_+_12865746 1.92 ENSDART00000157083
ralgapa1
Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr18_+_13315739 1.90 ENSDART00000143404
si:ch211-260p9.3
si:ch211-260p9.3
chr7_+_24393678 1.89 ENSDART00000188690
haus3
HAUS augmin-like complex, subunit 3
chr13_+_28819768 1.88 ENSDART00000191401
ENSDART00000188895
ENSDART00000101653
CU639469.1

chr10_-_35186310 1.88 ENSDART00000127805
pom121
POM121 transmembrane nucleoporin
chr8_+_36560019 1.87 ENSDART00000136418
ENSDART00000061378
ENSDART00000185237
sf3a1
splicing factor 3a, subunit 1
chr7_-_59564011 1.82 ENSDART00000186053
zgc:112271
zgc:112271
chr14_+_22132896 1.79 ENSDART00000138274
ccng1
cyclin G1
chr12_-_26587231 1.78 ENSDART00000153168
slc16a5a
solute carrier family 16 (monocarboxylate transporter), member 5a
chr16_-_25680666 1.77 ENSDART00000132693
ENSDART00000140539
ENSDART00000015302
tomm40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr17_+_654759 1.76 ENSDART00000193703
CABZ01079748.1

chr3_+_20012891 1.74 ENSDART00000078974
tmub2
transmembrane and ubiquitin-like domain containing 2
chr23_-_43486714 1.74 ENSDART00000169726
e2f1
E2F transcription factor 1
chr1_-_49947290 1.73 ENSDART00000141476
sgms2
sphingomyelin synthase 2
chr5_+_22264051 1.72 ENSDART00000143314
arhgap20b
Rho GTPase activating protein 20b
chr23_+_42336084 1.67 ENSDART00000158959
ENSDART00000161812
cyp2aa7
cyp2aa8
cytochrome P450, family 2, subfamily AA, polypeptide 7
cytochrome P450, family 2, subfamily AA, polypeptide 8
chr25_+_13406069 1.67 ENSDART00000010495
znrf1
zinc and ring finger 1
chr3_+_23743139 1.64 ENSDART00000187409
hoxb3a
homeobox B3a
chr2_+_37762924 1.64 ENSDART00000156530
ftr66
finTRIM family, member 66
chr19_+_48019070 1.62 ENSDART00000158269
UBE2M
si:ch1073-205c8.3
chr6_-_11812224 1.62 ENSDART00000150989
march7
membrane-associated ring finger (C3HC4) 7
chr20_-_43742822 1.62 ENSDART00000181729
si:dkeyp-50f7.2
si:dkeyp-50f7.2
chr6_+_202367 1.60 ENSDART00000168232
mgat3b
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase b
chr1_+_10297027 1.60 ENSDART00000152562
eif3f
eukaryotic translation initiation factor 3, subunit F
chr13_+_11876437 1.60 ENSDART00000179753
trim8a
tripartite motif containing 8a
chr22_-_10752471 1.59 ENSDART00000081191
sass6
SAS-6 centriolar assembly protein
chr16_+_31922065 1.59 ENSDART00000131661
ENSDART00000144194
ENSDART00000145510
rps9
ribosomal protein S9
chr16_+_16529748 1.59 ENSDART00000029579
ccdc12
coiled-coil domain containing 12
chr6_-_41536323 1.57 ENSDART00000113157
hemk1
HemK methyltransferase family member 1
chr9_+_21277846 1.57 ENSDART00000139620
ENSDART00000110996
ENSDART00000111899
lats2
large tumor suppressor kinase 2
chr23_-_4705110 1.55 ENSDART00000144536
ENSDART00000129050
ENSDART00000136399
cnbpa
CCHC-type zinc finger, nucleic acid binding protein a
chr10_-_27197044 1.55 ENSDART00000137928
auts2a
autism susceptibility candidate 2a
chr17_+_49091661 1.54 ENSDART00000177166
ENSDART00000177390
ENSDART00000190114
tiam2a
T cell lymphoma invasion and metastasis 2a
chr1_+_8521323 1.54 ENSDART00000121439
ENSDART00000103626
ENSDART00000141283
mief2
mitochondrial elongation factor 2
chr15_+_11825366 1.53 ENSDART00000190042
prkd2
protein kinase D2
chr6_+_25213934 1.52 ENSDART00000163440
si:ch73-97h19.2
si:ch73-97h19.2
chr12_-_7807298 1.52 ENSDART00000191355
ank3b
ankyrin 3b
chr20_+_30939178 1.51 ENSDART00000062556
sod2
superoxide dismutase 2, mitochondrial
chr3_+_54581987 1.51 ENSDART00000018071
eif3g
eukaryotic translation initiation factor 3, subunit G
chr6_-_40882880 1.50 ENSDART00000181706
sirt4
sirtuin 4
chr24_-_2312868 1.46 ENSDART00000140125
ENSDART00000138432
cul2
cullin 2
chr1_-_24918686 1.46 ENSDART00000148076
fbxw7
F-box and WD repeat domain containing 7
chr16_-_24550029 1.46 ENSDART00000108590
si:ch211-79k12.1
si:ch211-79k12.1
chr3_+_32411343 1.46 ENSDART00000186287
ENSDART00000141793
rras
RAS related
chr4_-_5831036 1.44 ENSDART00000166232
foxm1
forkhead box M1
chr4_+_6032640 1.42 ENSDART00000157487
tfec
transcription factor EC
chr15_-_4616816 1.40 ENSDART00000160191
ENSDART00000161721
ENSDART00000144949
eif4h
eukaryotic translation initiation factor 4h
chr16_+_20055878 1.39 ENSDART00000146436
ankrd28b
ankyrin repeat domain 28b
chr3_+_34149337 1.39 ENSDART00000006091
carm1
coactivator-associated arginine methyltransferase 1
chr3_+_22591395 1.39 ENSDART00000190526
tanc2a
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2a
chr12_+_36109507 1.39 ENSDART00000175409
map2k6
mitogen-activated protein kinase kinase 6
chr18_+_44673990 1.38 ENSDART00000018625
napab
N-ethylmaleimide-sensitive factor attachment protein, alpha b
chr11_-_29657947 1.35 ENSDART00000125753
rpl22
ribosomal protein L22
chr13_+_51710725 1.33 ENSDART00000163741
pwwp2b
PWWP domain containing 2B
chr3_-_22366562 1.33 ENSDART00000129447
ifnphi1
interferon phi 1
chr17_-_50022827 1.31 ENSDART00000161008
filip1a
filamin A interacting protein 1a
chr14_+_31493306 1.30 ENSDART00000138341
phf6
PHD finger protein 6
chr16_-_46578523 1.30 ENSDART00000131061
si:dkey-152b24.6
si:dkey-152b24.6
chr13_+_45524475 1.29 ENSDART00000074567
ENSDART00000019113
maco1b
macoilin 1b
chr8_+_10869183 1.28 ENSDART00000188111
brpf3b
bromodomain and PHD finger containing, 3b
chr7_+_9981757 1.28 ENSDART00000113429
ENSDART00000173233
adamts17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr2_-_38080075 1.27 ENSDART00000056544
tox4a
TOX high mobility group box family member 4 a
chr8_+_52377516 1.26 ENSDART00000115398
arid5a
AT rich interactive domain 5A (MRF1-like)
chr9_+_21306902 1.24 ENSDART00000138554
ENSDART00000004108
xpo4
exportin 4
chr23_-_16737161 1.24 ENSDART00000132573
si:ch211-224l10.4
si:ch211-224l10.4
chr10_-_8672820 1.23 ENSDART00000080763
si:dkey-27b3.2
si:dkey-27b3.2
chr7_-_66126628 1.23 ENSDART00000184492
btbd10b
BTB (POZ) domain containing 10b
chr21_+_45816030 1.23 ENSDART00000187056
pitx1
paired-like homeodomain 1
chr3_-_31619463 1.22 ENSDART00000124559
moto
minamoto
chr5_-_13645995 1.22 ENSDART00000099665
ENSDART00000166957
purba
purine-rich element binding protein Ba
chr11_-_39105253 1.22 ENSDART00000102827
p3h1
prolyl 3-hydroxylase 1
chr21_-_3007412 1.21 ENSDART00000190839
CKS2
zgc:86839
chr5_+_30520249 1.20 ENSDART00000013431
hmbsa
hydroxymethylbilane synthase a
chr2_+_24936766 1.20 ENSDART00000025962
gyg1a
glycogenin 1a
chr6_-_138392 1.18 ENSDART00000148974
keap1b
kelch-like ECH-associated protein 1b
chr5_-_16472719 1.17 ENSDART00000162071
piwil2
piwi-like RNA-mediated gene silencing 2
chr18_-_21177674 1.16 ENSDART00000060175
si:dkey-12e7.4
si:dkey-12e7.4
chr18_-_24988645 1.16 ENSDART00000136434
ENSDART00000085735
chd2
chromodomain helicase DNA binding protein 2
chr18_-_5111449 1.14 ENSDART00000046902
pdcd10a
programmed cell death 10a
chr15_-_36347858 1.14 ENSDART00000155274
ENSDART00000157936
si:dkey-23k10.2
si:dkey-23k10.2

Network of associatons between targets according to the STRING database.

First level regulatory network of znf711

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 46.8 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
3.1 12.3 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
2.2 6.5 GO:0030043 actin filament fragmentation(GO:0030043)
1.8 7.2 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
1.8 5.3 GO:1902895 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
1.5 17.0 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
1.4 4.1 GO:0048389 intermediate mesoderm development(GO:0048389)
1.2 5.0 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
1.2 4.9 GO:0045903 positive regulation of translational fidelity(GO:0045903)
1.2 5.9 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.9 2.8 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
0.9 3.4 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.8 2.4 GO:0001783 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.8 2.3 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.7 2.0 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.7 7.4 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.7 4.7 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.7 2.0 GO:0002369 T cell cytokine production(GO:0002369)
0.6 5.2 GO:0048730 epidermis morphogenesis(GO:0048730)
0.6 2.3 GO:0003161 cardiac conduction system development(GO:0003161)
0.5 5.2 GO:0086003 cardiac muscle cell contraction(GO:0086003)
0.5 1.5 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.5 1.5 GO:0031645 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.5 4.2 GO:0001780 neutrophil homeostasis(GO:0001780)
0.5 3.7 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.4 3.6 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.4 6.2 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.4 5.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.4 1.1 GO:1903358 regulation of Golgi organization(GO:1903358)
0.3 5.2 GO:0042407 cristae formation(GO:0042407)
0.3 1.4 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.3 38.8 GO:0031101 fin regeneration(GO:0031101)
0.3 1.4 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.3 5.1 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.3 3.0 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.3 2.4 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 3.4 GO:0006108 malate metabolic process(GO:0006108)
0.3 0.9 GO:2000374 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.3 10.7 GO:0030199 collagen fibril organization(GO:0030199)
0.3 5.9 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.3 1.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.3 2.6 GO:0003139 secondary heart field specification(GO:0003139)
0.3 2.0 GO:0097107 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.3 2.7 GO:0046661 male sex differentiation(GO:0046661)
0.3 1.3 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.3 1.3 GO:0023041 neuronal signal transduction(GO:0023041)
0.3 5.2 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.3 1.5 GO:0089700 protein kinase D signaling(GO:0089700)
0.3 47.4 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.2 2.7 GO:0030719 P granule organization(GO:0030719)
0.2 1.6 GO:0040016 embryonic cleavage(GO:0040016)
0.2 2.2 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.2 6.9 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.2 1.4 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.2 1.2 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.2 4.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 1.7 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.2 0.8 GO:0061015 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.2 4.0 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 1.4 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.2 2.5 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.2 1.2 GO:0007141 male meiosis I(GO:0007141)
0.2 2.9 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.2 2.3 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.2 3.9 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.2 2.3 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.2 1.7 GO:0021535 cell migration in hindbrain(GO:0021535)
0.1 2.0 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.4 GO:1990120 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833) messenger ribonucleoprotein complex assembly(GO:1990120)
0.1 0.7 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 2.1 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 1.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 7.8 GO:0006414 translational elongation(GO:0006414)
0.1 5.8 GO:0045214 sarcomere organization(GO:0045214)
0.1 1.3 GO:0006611 protein export from nucleus(GO:0006611)
0.1 1.2 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 10.3 GO:0061515 myeloid cell development(GO:0061515)
0.1 2.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.9 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.8 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.1 1.6 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 1.9 GO:0010634 positive regulation of epithelial cell migration(GO:0010634)
0.1 1.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.9 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 1.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 1.3 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 3.8 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.1 0.3 GO:0021693 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698)
0.1 3.8 GO:0070972 protein localization to endoplasmic reticulum(GO:0070972)
0.1 0.9 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 2.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 2.6 GO:0035194 posttranscriptional gene silencing(GO:0016441) posttranscriptional gene silencing by RNA(GO:0035194)
0.1 1.3 GO:0033077 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.1 2.6 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 1.5 GO:0021884 forebrain neuron development(GO:0021884)
0.1 0.2 GO:0010712 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246)
0.1 2.3 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.1 1.8 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 3.6 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.7 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.7 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.1 1.0 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.9 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 3.1 GO:0048484 enteric nervous system development(GO:0048484)
0.1 0.7 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 1.7 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 1.3 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.4 GO:0060004 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.0 1.0 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 3.8 GO:1902667 regulation of axon guidance(GO:1902667)
0.0 1.2 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.4 GO:0061709 reticulophagy(GO:0061709)
0.0 1.8 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 1.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.7 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 0.5 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 6.5 GO:0061053 somite development(GO:0061053)
0.0 0.9 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 1.2 GO:0032963 collagen metabolic process(GO:0032963) multicellular organismal macromolecule metabolic process(GO:0044259)
0.0 0.8 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.3 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.2 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.0 5.0 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 1.9 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 1.5 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 0.4 GO:0060729 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.6 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.6 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 1.2 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 1.3 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 6.0 GO:0010564 regulation of cell cycle process(GO:0010564)
0.0 0.5 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.6 GO:0006479 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0 1.9 GO:0007517 muscle organ development(GO:0007517)
0.0 0.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 1.5 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 1.8 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.6 GO:0032508 DNA geometric change(GO:0032392) DNA duplex unwinding(GO:0032508)
0.0 0.2 GO:0006501 C-terminal protein lipidation(GO:0006501) lysosomal microautophagy(GO:0016237) C-terminal protein amino acid modification(GO:0018410) piecemeal microautophagy of nucleus(GO:0034727) single-organism membrane invagination(GO:1902534)
0.0 3.4 GO:0009953 dorsal/ventral pattern formation(GO:0009953)
0.0 1.4 GO:0006413 translational initiation(GO:0006413)
0.0 0.9 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.7 GO:0002548 monocyte chemotaxis(GO:0002548)
0.0 0.1 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 1.6 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 1.3 GO:0006006 glucose metabolic process(GO:0006006)
0.0 3.6 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 3.2 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.7 GO:0071897 DNA biosynthetic process(GO:0071897)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.0 GO:0009615 response to virus(GO:0009615)
0.0 0.6 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 0.6 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.5 GO:0050982 detection of mechanical stimulus(GO:0050982)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 27.4 GO:0045095 keratin filament(GO:0045095)
1.3 5.2 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
1.0 7.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
1.0 21.4 GO:0031430 M band(GO:0031430)
0.9 14.1 GO:0005869 dynactin complex(GO:0005869)
0.8 38.7 GO:0031941 filamentous actin(GO:0031941)
0.8 3.1 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.5 1.6 GO:0098536 deuterosome(GO:0098536)
0.5 5.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.5 5.2 GO:0061617 MICOS complex(GO:0061617)
0.5 9.0 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.4 1.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.4 1.1 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.4 1.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.4 33.0 GO:0005581 collagen trimer(GO:0005581)
0.3 1.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.3 15.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 6.9 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.3 4.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.3 2.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.3 0.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 2.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 1.2 GO:1990923 PET complex(GO:1990923)
0.2 1.9 GO:0070652 HAUS complex(GO:0070652)
0.2 1.2 GO:0016234 inclusion body(GO:0016234)
0.2 0.9 GO:0097433 dense body(GO:0097433)
0.2 5.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 2.3 GO:0005922 connexon complex(GO:0005922)
0.2 1.0 GO:0016589 NURF complex(GO:0016589)
0.2 2.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 1.8 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.4 GO:0042382 paraspeckles(GO:0042382)
0.1 0.5 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.1 8.7 GO:0005884 actin filament(GO:0005884)
0.1 0.5 GO:0060171 stereocilium membrane(GO:0060171)
0.1 1.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.9 GO:0072487 MSL complex(GO:0072487)
0.1 0.5 GO:0005899 insulin receptor complex(GO:0005899)
0.1 1.6 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 2.5 GO:0071004 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.1 0.9 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 2.6 GO:0043186 P granule(GO:0043186)
0.1 2.8 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.7 GO:0001772 immunological synapse(GO:0001772)
0.1 2.4 GO:0005839 proteasome core complex(GO:0005839)
0.1 0.9 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.5 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.1 1.4 GO:0042555 MCM complex(GO:0042555)
0.1 4.7 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 0.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.0 GO:0036038 MKS complex(GO:0036038)
0.1 1.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 8.9 GO:0030017 sarcomere(GO:0030017)
0.0 1.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.4 GO:0005687 U4 snRNP(GO:0005687)
0.0 1.4 GO:0005840 ribosome(GO:0005840)
0.0 2.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.8 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 4.1 GO:0016607 nuclear speck(GO:0016607)
0.0 1.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.9 GO:0016605 PML body(GO:0016605)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 29.3 GO:0005739 mitochondrion(GO:0005739)
0.0 7.9 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 2.1 GO:0000922 spindle pole(GO:0000922)
0.0 1.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 35.0 GO:0005576 extracellular region(GO:0005576)
0.0 4.9 GO:0000785 chromatin(GO:0000785)
0.0 5.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 3.1 GO:0030425 dendrite(GO:0030425)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 46.8 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
1.9 38.7 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
1.3 5.0 GO:0033149 FFAT motif binding(GO:0033149)
0.9 3.4 GO:1990931 RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.8 3.4 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.8 4.7 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.7 2.8 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.6 6.0 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.6 4.8 GO:0036122 BMP binding(GO:0036122)
0.6 4.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.6 2.3 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.6 6.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.5 2.3 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.5 5.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.4 1.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.4 10.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.4 2.3 GO:0005536 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.3 0.9 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.3 1.2 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.3 6.1 GO:0003785 actin monomer binding(GO:0003785)
0.3 2.0 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.3 1.4 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.3 35.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 0.8 GO:0052855 ATP-dependent NAD(P)H-hydrate dehydratase activity(GO:0047453) ADP-dependent NAD(P)H-hydrate dehydratase activity(GO:0052855)
0.2 2.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 5.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.2 2.1 GO:0035198 miRNA binding(GO:0035198)
0.2 1.4 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.2 1.2 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.2 1.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.2 0.8 GO:0005521 lamin binding(GO:0005521)
0.2 2.9 GO:2001069 glycogen binding(GO:2001069)
0.2 1.5 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 0.7 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.2 8.2 GO:0019843 rRNA binding(GO:0019843)
0.2 8.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 0.9 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.2 5.1 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 1.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 6.6 GO:0045182 translation regulator activity(GO:0045182)
0.1 1.2 GO:0034584 piRNA binding(GO:0034584)
0.1 0.7 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 2.1 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.9 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 2.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 1.8 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 0.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.7 GO:0019202 amino acid kinase activity(GO:0019202)
0.1 1.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.7 GO:0008142 oxysterol binding(GO:0008142)
0.1 1.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.5 GO:0005009 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.1 0.7 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 2.7 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 1.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 6.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 1.5 GO:0008143 poly(A) binding(GO:0008143)
0.1 9.1 GO:0042803 protein homodimerization activity(GO:0042803)
0.1 2.0 GO:0019213 deacetylase activity(GO:0019213)
0.1 1.5 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 1.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 2.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 4.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 5.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 1.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 8.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.9 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 3.9 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 4.0 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.9 GO:0070411 I-SMAD binding(GO:0070411)
0.0 1.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 6.9 GO:0005179 hormone activity(GO:0005179)
0.0 6.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 3.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.8 GO:0048038 quinone binding(GO:0048038)
0.0 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.9 GO:0044325 ion channel binding(GO:0044325)
0.0 1.0 GO:0035064 methylated histone binding(GO:0035064)
0.0 3.2 GO:0008201 heparin binding(GO:0008201)
0.0 1.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.0 2.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 1.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.4 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 1.8 GO:0051536 iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.0 2.2 GO:0004386 helicase activity(GO:0004386)
0.0 15.9 GO:0003779 actin binding(GO:0003779)
0.0 1.7 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 0.8 GO:0051087 chaperone binding(GO:0051087)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 1.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.6 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.6 GO:0019003 GDP binding(GO:0019003)
0.0 7.0 GO:0046983 protein dimerization activity(GO:0046983)
0.0 1.6 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.4 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 5.1 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 0.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 2.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.4 GO:0017069 snRNA binding(GO:0017069)
0.0 1.3 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 31.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.4 9.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.3 5.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.3 5.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 2.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.2 4.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.2 3.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 2.7 ST GA12 PATHWAY G alpha 12 Pathway
0.2 2.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.2 PID ARF 3PATHWAY Arf1 pathway
0.1 1.7 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 1.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 3.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 1.0 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 1.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 5.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 0.8 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 2.0 PID RAS PATHWAY Regulation of Ras family activation
0.1 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 0.9 PID ALK2 PATHWAY ALK2 signaling events
0.1 2.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 5.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 0.8 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.9 PID FOXO PATHWAY FoxO family signaling
0.0 0.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.8 PID E2F PATHWAY E2F transcription factor network
0.0 1.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.4 18.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.4 1.4 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.3 6.0 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.3 2.5 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.3 10.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.3 3.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.2 2.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 2.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.2 5.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.2 3.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.2 1.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 1.0 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 1.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 2.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 4.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 1.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 2.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 3.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 5.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 6.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 2.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 0.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 2.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 2.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 8.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 2.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 4.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis