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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for znf740b

Z-value: 0.83

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Transcription factors associated with znf740b

Gene Symbol Gene ID Gene Info
znf740b
ENSDARG00000061174 zinc finger protein 740b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
znf740bdr11_v1_chr23_-_36418708_364187080.471.5e-06Click!

Activity profile of znf740b motif

Sorted Z-values of znf740b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_36803415 8.20 ENSDART00000111680
iqsec2b
IQ motif and Sec7 domain 2b
chr25_+_4750972 7.59 ENSDART00000168903
si:zfos-2372e4.1
si:zfos-2372e4.1
chr11_-_3334248 7.09 ENSDART00000154314
ENSDART00000121861
prph
peripherin
chr11_-_24191928 6.24 ENSDART00000136827
sox12
SRY (sex determining region Y)-box 12
chr2_+_22694382 5.20 ENSDART00000139196
kif1ab
kinesin family member 1Ab
chr1_+_39553040 5.02 ENSDART00000137676
tenm3
teneurin transmembrane protein 3
chr25_+_30196039 4.87 ENSDART00000005299
hsd17b12a
hydroxysteroid (17-beta) dehydrogenase 12a
chr3_-_61162750 4.49 ENSDART00000055064
pvalb8
parvalbumin 8
chr25_+_37366698 4.39 ENSDART00000165400
ENSDART00000192589
slc1a2b
solute carrier family 1 (glial high affinity glutamate transporter), member 2b
chr24_+_41931585 4.19 ENSDART00000130310
epb41l3a
erythrocyte membrane protein band 4.1-like 3a
chr10_+_1849874 4.01 ENSDART00000158897
ENSDART00000149956
apc
adenomatous polyposis coli
chr5_+_31214341 4.00 ENSDART00000133432
atp2a3
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr1_-_42778510 3.99 ENSDART00000190172
lrrtm1
leucine rich repeat transmembrane neuronal 1
chr11_-_97817 3.94 ENSDART00000092903
elmo2
engulfment and cell motility 2
chr21_+_13389499 3.91 ENSDART00000151268
zgc:113162
zgc:113162
chr23_-_10175898 3.58 ENSDART00000146185
krt5
keratin 5
chr20_+_26538137 3.54 ENSDART00000045397
stx11b.1
syntaxin 11b, tandem duplicate 1
chr16_-_17586883 3.48 ENSDART00000017142
m6pr
mannose-6-phosphate receptor (cation dependent)
chr22_-_20403194 3.45 ENSDART00000010048
map2k2a
mitogen-activated protein kinase kinase 2a
chr23_+_6232895 3.43 ENSDART00000139795
syt2a
synaptotagmin IIa
chr1_+_31112436 3.41 ENSDART00000075340
eef1a1b
eukaryotic translation elongation factor 1 alpha 1b
chr6_+_58492201 3.40 ENSDART00000156375
kcnq2b
potassium voltage-gated channel, KQT-like subfamily, member 2b
chr16_-_31435020 3.35 ENSDART00000138508
zgc:194210
zgc:194210
chr6_+_38381957 3.30 ENSDART00000087300
gabrb3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr20_+_20672163 3.30 ENSDART00000027758
rtn1b
reticulon 1b
chr20_-_25542183 3.30 ENSDART00000024350
cyp2ad2
cytochrome P450, family 2, subfamily AD, polypeptide 2
chr17_-_12389259 3.24 ENSDART00000185724
snap25b
synaptosomal-associated protein, 25b
chr12_+_24561832 3.19 ENSDART00000088159
nrxn1a
neurexin 1a
chr3_-_50998577 3.17 ENSDART00000157735
cdc42ep4a
CDC42 effector protein (Rho GTPase binding) 4a
chr7_-_27686021 3.11 ENSDART00000079112
ENSDART00000100989
calca
calcitonin/calcitonin-related polypeptide, alpha
chr2_-_16565690 3.04 ENSDART00000022549
atp1b3a
ATPase Na+/K+ transporting subunit beta 3a
chr21_+_1143141 3.00 ENSDART00000178294
CABZ01086139.1

chr14_+_22172047 2.97 ENSDART00000114750
ENSDART00000148259
gabrb2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr10_-_17170086 2.95 ENSDART00000020122
ywhah
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr16_-_25393699 2.92 ENSDART00000149445
pard6ga
par-6 family cell polarity regulator gamma a
chr13_-_27767330 2.84 ENSDART00000131631
ENSDART00000112553
ENSDART00000189911
rims1a
regulating synaptic membrane exocytosis 1a
chr11_+_25101220 2.80 ENSDART00000183700
ndrg3a
ndrg family member 3a
chr5_+_32162684 2.78 ENSDART00000134472
taok3b
TAO kinase 3b
chr14_+_31566517 2.72 ENSDART00000002684
ints6l
integrator complex subunit 6 like
chr11_+_38280454 2.70 ENSDART00000171496
CDK18
si:dkey-166c18.1
chr13_+_11439486 2.70 ENSDART00000138312
zbtb18
zinc finger and BTB domain containing 18
chr1_-_42779075 2.69 ENSDART00000133917
lrrtm1
leucine rich repeat transmembrane neuronal 1
chr15_-_28618502 2.67 ENSDART00000086902
slc6a4a
solute carrier family 6 (neurotransmitter transporter), member 4a
chr3_+_21189766 2.64 ENSDART00000078807
zgc:123295
zgc:123295
chr5_-_14326959 2.61 ENSDART00000137355
tet3
tet methylcytosine dioxygenase 3
chr18_+_35742838 2.59 ENSDART00000088504
ENSDART00000140386
rasgrp4
RAS guanyl releasing protein 4
chr25_+_4091067 2.54 ENSDART00000104926
eps8l2
EPS8 like 2
chr21_+_22878834 2.50 ENSDART00000065562
pcf11
PCF11 cleavage and polyadenylation factor subunit
chr8_-_31107537 2.46 ENSDART00000098925
vgll4l
vestigial like 4 like
chr13_-_638485 2.44 ENSDART00000066080
ENSDART00000128969
slit1a
slit homolog 1a (Drosophila)
chr9_-_31278048 2.41 ENSDART00000022204
zic5
zic family member 5 (odd-paired homolog, Drosophila)
chr9_+_29585943 2.40 ENSDART00000185989
ENSDART00000115290
mcf2lb
mcf.2 cell line derived transforming sequence-like b
chr19_+_13994563 2.39 ENSDART00000164696
tmem222b
transmembrane protein 222b
chr17_+_37310663 2.31 ENSDART00000157122
elmsan1b
ELM2 and Myb/SANT-like domain containing 1b
chr21_+_30351256 2.31 ENSDART00000078341
foxi3a
forkhead box I3a
chr25_-_11088839 2.30 ENSDART00000154748
sv2bb
synaptic vesicle glycoprotein 2Bb
chr22_+_24157807 2.29 ENSDART00000159165
b3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr3_-_31804481 2.28 ENSDART00000028270
gfap
glial fibrillary acidic protein
chr21_-_9446747 2.28 ENSDART00000158790
ptpn13
protein tyrosine phosphatase, non-receptor type 13
chr23_+_5977965 2.23 ENSDART00000115403
ENSDART00000183147
NAV1 (1 of many)
neuron navigator 1
chr12_+_42436328 2.23 ENSDART00000167324
ebf3a
early B cell factor 3a
chr10_-_35542071 2.22 ENSDART00000162139
si:ch211-244c8.4
si:ch211-244c8.4
chr16_-_47245563 2.21 ENSDART00000190225
LO017877.2

chr23_+_39346930 2.12 ENSDART00000102843
src
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr3_+_13440900 2.10 ENSDART00000143715
GNG14
si:dkey-117i10.1
chr9_-_32177117 2.09 ENSDART00000078568
sf3b1
splicing factor 3b, subunit 1
chr16_-_9879407 2.07 ENSDART00000149424
ncalda
neurocalcin delta a
chr8_+_25267903 2.06 ENSDART00000093090
ampd2b
adenosine monophosphate deaminase 2b
chr16_+_1803462 2.06 ENSDART00000183974
GRIK2
glutamate ionotropic receptor kainate type subunit 2
chr20_-_35246150 2.05 ENSDART00000090549
fzd3a
frizzled class receptor 3a
chr21_+_7823146 2.04 ENSDART00000030579
crhbp
corticotropin releasing hormone binding protein
chr16_-_24672919 2.02 ENSDART00000008326
pon2
paraoxonase 2
chr8_+_28900689 1.98 ENSDART00000141634
grid2
glutamate receptor, ionotropic, delta 2
chr8_-_23776399 1.97 ENSDART00000114800
INAVA
si:ch211-163l21.4
chr9_-_18877597 1.97 ENSDART00000099446
kctd4
potassium channel tetramerization domain containing 4
chr17_+_52822422 1.96 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr5_+_36614196 1.95 ENSDART00000150574
nova1
neuro-oncological ventral antigen 1
chr3_-_26204867 1.94 ENSDART00000103748
gdpd3a
glycerophosphodiester phosphodiesterase domain containing 3a
chr22_-_5839686 1.92 ENSDART00000145406
si:rp71-36a1.5
si:rp71-36a1.5
chr15_-_35246742 1.90 ENSDART00000131479
mff
mitochondrial fission factor
chr21_+_11244068 1.88 ENSDART00000163432
arid6
AT-rich interaction domain 6
chr2_+_37245382 1.88 ENSDART00000004626
sec62
SEC62 homolog, preprotein translocation factor
chr17_+_5846202 1.87 ENSDART00000189713
fndc4b
fibronectin type III domain containing 4b
chr1_-_8012476 1.87 ENSDART00000177051
CR855320.3

chr7_+_23495986 1.87 ENSDART00000190739
ENSDART00000115299
ENSDART00000101423
ENSDART00000142401
zgc:109889
zgc:109889
chr11_-_4235811 1.87 ENSDART00000121716
si:ch211-236d3.4
si:ch211-236d3.4
chr9_+_7358749 1.87 ENSDART00000081660
ihha
Indian hedgehog homolog a
chr16_-_27749172 1.87 ENSDART00000145198
steap4
STEAP family member 4
chr9_+_13714379 1.86 ENSDART00000017593
ENSDART00000145503
tmem237a
transmembrane protein 237a
chr13_-_45523026 1.85 ENSDART00000020663
rhd
Rh blood group, D antigen
chr13_+_23677949 1.84 ENSDART00000144215
pcnxl2
pecanex-like 2 (Drosophila)
chr12_-_20584413 1.82 ENSDART00000170923
FP885542.2

chr6_-_29377092 1.82 ENSDART00000078665
tmem131
transmembrane protein 131
chr9_-_32753535 1.81 ENSDART00000060006
olig2
oligodendrocyte lineage transcription factor 2
chr5_-_67115872 1.79 ENSDART00000065262
rps6ka4
ribosomal protein S6 kinase, polypeptide 4
chr12_-_14211293 1.79 ENSDART00000158399
avl9
AVL9 homolog (S. cerevisiase)
chr5_-_35264517 1.79 ENSDART00000114981
ptcd2
pentatricopeptide repeat domain 2
chr9_-_23807032 1.78 ENSDART00000027443
esyt3
extended synaptotagmin-like protein 3
chr18_+_21122818 1.78 ENSDART00000060015
ENSDART00000060184
chka
choline kinase alpha
chr15_+_3790556 1.77 ENSDART00000181467
RNF14 (1 of many)
ring finger protein 14
chr8_+_36270571 1.75 ENSDART00000187505
CU929676.1

chr20_-_37629084 1.74 ENSDART00000141734
hivep2a
human immunodeficiency virus type I enhancer binding protein 2a
chr2_-_23004286 1.74 ENSDART00000134664
ENSDART00000110373
ENSDART00000185833
ENSDART00000187235
znf414
mllt1b
zinc finger protein 414
MLLT1, super elongation complex subunit b
chr10_-_22249444 1.73 ENSDART00000148831
fgf11b
fibroblast growth factor 11b
chr20_-_20610812 1.73 ENSDART00000181870
ppm1ab
protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
chr2_+_58221163 1.72 ENSDART00000157939
FO704813.1

chr9_+_8942258 1.69 ENSDART00000138836
ankrd10b
ankyrin repeat domain 10b
chr19_+_2602903 1.68 ENSDART00000033132
fam126a
family with sequence similarity 126, member A
chr1_-_38709551 1.66 ENSDART00000128794
gpm6ab
glycoprotein M6Ab
chr21_-_30181732 1.63 ENSDART00000015636
hnrnph1l
heterogeneous nuclear ribonucleoprotein H1, like
chr15_-_37543839 1.56 ENSDART00000148870
kmt2bb
lysine (K)-specific methyltransferase 2Bb
chr14_-_2369849 1.56 ENSDART00000180422
ENSDART00000189731
ENSDART00000111748
pcdhb
protocadherin b
chr7_-_2039060 1.56 ENSDART00000173879
si:cabz01007794.1
si:cabz01007794.1
chr2_+_43469241 1.56 ENSDART00000142078
ENSDART00000098265
nrp1b
neuropilin 1b
chr5_+_42912966 1.55 ENSDART00000039973
rufy3
RUN and FYVE domain containing 3
chr13_+_2830574 1.54 ENSDART00000138143
si:ch211-233m11.1
si:ch211-233m11.1
chr5_-_70625697 1.52 ENSDART00000179538
ENSDART00000190540
CABZ01075572.1

chr7_-_19043401 1.51 ENSDART00000158796
fcer1g
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chr18_+_46151505 1.51 ENSDART00000015034
ENSDART00000141287
blvrb
biliverdin reductase B
chr6_+_38845697 1.50 ENSDART00000053187
stk35l
serine/threonine kinase 35, like
chr18_+_41232719 1.49 ENSDART00000138552
ENSDART00000145863
trip12
thyroid hormone receptor interactor 12
chr25_+_35502552 1.49 ENSDART00000189612
ENSDART00000058443
fibina
fin bud initiation factor a
chr14_+_33458294 1.46 ENSDART00000075278
atp1b4
ATPase Na+/K+ transporting subunit beta 4
chr2_+_47623202 1.46 ENSDART00000154465
si:ch211-165b10.3
si:ch211-165b10.3
chr2_-_36818132 1.45 ENSDART00000110447
slitrk3b
SLIT and NTRK-like family, member 3b
chr11_+_6650966 1.45 ENSDART00000131236
si:dkey-246j7.1
si:dkey-246j7.1
chr6_-_30859656 1.44 ENSDART00000156235
pde4ba
phosphodiesterase 4B, cAMP-specific a
chr25_-_19395476 1.44 ENSDART00000182622
map1ab
microtubule-associated protein 1Ab
chr2_+_28889936 1.42 ENSDART00000078232
cdh10a
cadherin 10, type 2a (T2-cadherin)
chr3_-_33417826 1.41 ENSDART00000084284
abi3a
ABI family, member 3a
chr11_-_23322182 1.40 ENSDART00000111289
kiss1
KiSS-1 metastasis-suppressor
chr15_-_37543591 1.39 ENSDART00000180400
kmt2bb
lysine (K)-specific methyltransferase 2Bb
chr3_+_37824268 1.39 ENSDART00000137038
asic2
acid-sensing (proton-gated) ion channel 2
chr4_+_34417403 1.38 ENSDART00000186032
ENSDART00000167909
si:ch211-246b8.2
si:ch211-246b8.2
chr19_+_12406583 1.36 ENSDART00000013865
ENSDART00000151535
seh1l
SEH1-like (S. cerevisiae)
chr22_-_5918670 1.35 ENSDART00000141373
si:rp71-36a1.1
si:rp71-36a1.1
chr25_+_3788074 1.34 ENSDART00000154008
chid1
chitinase domain containing 1
chr10_-_43721530 1.34 ENSDART00000025366
cetn3
centrin 3
chr17_-_36988455 1.33 ENSDART00000187180
ENSDART00000126823
dnmt3ab
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr13_+_771403 1.32 ENSDART00000093166
nrxn1b
neurexin 1b
chr1_+_53842344 1.30 ENSDART00000114506
crfb17
cytokine receptor family member B17
chr3_+_62126981 1.29 ENSDART00000060527
drc3
dynein regulatory complex subunit 3
chr5_-_40190949 1.29 ENSDART00000175588
wdfy3
WD repeat and FYVE domain containing 3
chr2_-_37043540 1.28 ENSDART00000131834
gng7
guanine nucleotide binding protein (G protein), gamma 7
chr7_-_28611145 1.28 ENSDART00000054366
scube2
signal peptide, CUB domain, EGF-like 2
chr11_-_7139555 1.27 ENSDART00000016472
bmp7a
bone morphogenetic protein 7a
chr12_+_8003872 1.27 ENSDART00000180300
ENSDART00000126661
rhobtb1
Rho-related BTB domain containing 1
chr6_-_18121075 1.25 ENSDART00000171072
SEC14L1
si:dkey-237i9.1
chr22_+_35068046 1.25 ENSDART00000161660
ENSDART00000169573
si:ch73-173h19.3
si:ch73-173h19.3
chr11_+_7432533 1.24 ENSDART00000180977
adgrl2a
adhesion G protein-coupled receptor L2a
chr15_+_32643873 1.23 ENSDART00000189433
trpc4b
transient receptor potential cation channel, subfamily C, member 4b
chr19_-_7358184 1.23 ENSDART00000092379
oxr1b
oxidation resistance 1b
chr16_-_41439659 1.22 ENSDART00000191624
cpne4a
copine IVa
chr23_-_524780 1.22 ENSDART00000055139
col9a3
collagen, type IX, alpha 3
chr14_-_24111292 1.22 ENSDART00000186611
cpeb4a
cytoplasmic polyadenylation element binding protein 4a
chr2_-_44183613 1.21 ENSDART00000079596
cadm3
cell adhesion molecule 3
chr8_-_37328112 1.20 ENSDART00000140365
slc12a5b
solute carrier family 12 (potassium/chloride transporter), member 5b
chr8_-_23578660 1.20 ENSDART00000039080
wasb
Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b
chr6_-_34860574 1.18 ENSDART00000073957
slc35d1a
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1a
chr7_+_16835218 1.18 ENSDART00000173580
nav2a
neuron navigator 2a
chr12_-_22540943 1.15 ENSDART00000172310
zbtb4
zinc finger and BTB domain containing 4
chr6_+_23712911 1.15 ENSDART00000167795
zgc:158654
zgc:158654
chr16_-_39477746 1.14 ENSDART00000102525
stt3b
STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
chr17_-_2721336 1.14 ENSDART00000109582
ENSDART00000192691
ENSDART00000189381
spata7
spermatogenesis associated 7
chr22_-_6219674 1.13 ENSDART00000182582
si:ch211-274k16.2
si:ch211-274k16.2
chr10_+_8968203 1.13 ENSDART00000110443
ENSDART00000080772
fstb
follistatin b
chr10_-_43294933 1.12 ENSDART00000062631
hapln1b
hyaluronan and proteoglycan link protein 1b
chr20_+_23408970 1.12 ENSDART00000144261
fryl
furry homolog, like
chr7_+_31074636 1.10 ENSDART00000173805
tjp1a
tight junction protein 1a
chr23_+_41200854 1.10 ENSDART00000109567
nhsa
Nance-Horan syndrome a (congenital cataracts and dental anomalies)
chr25_+_25464630 1.09 ENSDART00000150537
rassf7a
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7a
chr18_-_16181952 1.08 ENSDART00000157824
slc6a15
solute carrier family 6 (neutral amino acid transporter), member 15
chr10_-_39283883 1.06 ENSDART00000023831
cry5
cryptochrome circadian clock 5
chr23_+_44580254 1.05 ENSDART00000185069
pfn1
profilin 1
chr17_-_33289304 1.05 ENSDART00000135118
ENSDART00000040346
efr3ba
EFR3 homolog Ba (S. cerevisiae)
chr24_-_40860603 1.04 ENSDART00000188032
CU633479.7

chr23_+_42434348 1.03 ENSDART00000161027
cyp2aa1
cytochrome P450, family 2, subfamily AA, polypeptide 1
chr25_+_3788443 1.03 ENSDART00000189747
chid1
chitinase domain containing 1
chr15_-_40267485 1.02 ENSDART00000152253
kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr9_-_28990649 1.02 ENSDART00000078823
ptpn4a
protein tyrosine phosphatase, non-receptor type 4a
chr23_+_22785375 1.01 ENSDART00000142085
rerea
arginine-glutamic acid dipeptide (RE) repeats a
chr7_+_36552725 1.01 ENSDART00000173682
chd9
chromodomain helicase DNA binding protein 9
chr8_+_26268100 1.01 ENSDART00000138882
slc26a6
solute carrier family 26, member 6
chr20_+_26394324 1.00 ENSDART00000078093
zbtb2b
zinc finger and BTB domain containing 2b
chr19_-_25519612 1.00 ENSDART00000133150
C1GALT1 (1 of many)
si:dkey-202e17.1
chr19_-_6873107 1.00 ENSDART00000124440
CABZ01029822.1

chr15_+_3125136 1.00 ENSDART00000130968
rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr2_+_33052169 1.00 ENSDART00000180008
rnf220a
ring finger protein 220a
chr10_-_43540196 0.99 ENSDART00000170891
si:ch73-215f7.1
si:ch73-215f7.1
chr5_-_42180205 0.99 ENSDART00000145247
fam222ba
family with sequence similarity 222, member Ba
chr1_-_51474974 0.98 ENSDART00000152719
spred2a
sprouty-related, EVH1 domain containing 2a
chr18_+_17959681 0.98 ENSDART00000142700
znf423
zinc finger protein 423
chr4_-_5795309 0.97 ENSDART00000039987
pgm3
phosphoglucomutase 3
chr13_+_30506781 0.96 ENSDART00000110884
zmiz1a
zinc finger, MIZ-type containing 1a
chr21_+_26733529 0.96 ENSDART00000168379
pcxa
pyruvate carboxylase a
chr16_-_30655980 0.96 ENSDART00000146508
ldlrad4b
low density lipoprotein receptor class A domain containing 4b
chr12_+_5530247 0.95 ENSDART00000114637
ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr16_-_8280885 0.95 ENSDART00000129068
entpd3
ectonucleoside triphosphate diphosphohydrolase 3
chr20_-_42100932 0.95 ENSDART00000191930
slc35f1
solute carrier family 35, member F1
chr10_+_10210455 0.94 ENSDART00000144214
sh2d3ca
SH2 domain containing 3Ca

Network of associatons between targets according to the STRING database.

First level regulatory network of znf740b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.0 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
1.0 4.0 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031) Wnt signaling pathway involved in somitogenesis(GO:0090244) negative regulation of canonical Wnt signaling pathway involved in heart development(GO:1905067)
0.7 2.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.7 2.0 GO:0090278 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.7 2.7 GO:0051610 serotonin transport(GO:0006837) serotonin uptake(GO:0051610)
0.6 4.9 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.6 2.3 GO:0009957 epidermal cell fate specification(GO:0009957)
0.5 2.6 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.5 1.9 GO:0015677 copper ion import(GO:0015677)
0.5 1.8 GO:0021742 abducens nucleus development(GO:0021742)
0.4 2.5 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.4 1.1 GO:0060031 mediolateral intercalation(GO:0060031)
0.4 2.5 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.3 2.4 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.3 3.2 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.3 3.5 GO:0006622 protein targeting to lysosome(GO:0006622)
0.3 4.2 GO:0051963 regulation of synapse assembly(GO:0051963)
0.3 1.8 GO:0016572 histone phosphorylation(GO:0016572)
0.3 6.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.3 1.1 GO:0061033 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.3 1.1 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.3 1.9 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.3 1.9 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.3 1.0 GO:0051876 pigment granule dispersal(GO:0051876)
0.2 1.5 GO:1902915 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.2 3.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 1.8 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.2 1.4 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.2 1.6 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.2 8.2 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 4.4 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.2 3.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 0.9 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591)
0.2 1.0 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.2 2.3 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2 3.0 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.2 1.4 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1 6.9 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.1 2.1 GO:0032264 IMP salvage(GO:0032264)
0.1 4.3 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 1.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 1.0 GO:0090311 regulation of histone deacetylation(GO:0031063) regulation of protein deacetylation(GO:0090311)
0.1 1.7 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.3 GO:0021754 facial nucleus development(GO:0021754)
0.1 1.8 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.0 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.1 3.0 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.1 0.6 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.1 1.3 GO:0042664 locus ceruleus development(GO:0021703) negative regulation of endodermal cell fate specification(GO:0042664)
0.1 2.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 3.5 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 1.3 GO:0042694 muscle cell fate specification(GO:0042694)
0.1 2.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 1.9 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279) post-translational protein modification(GO:0043687)
0.1 1.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.7 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 1.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.9 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.9 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.1 0.4 GO:0042481 regulation of odontogenesis(GO:0042481)
0.1 0.4 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.1 0.3 GO:0003242 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 1.9 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 2.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.4 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 1.1 GO:0097499 protein localization to nonmotile primary cilium(GO:0097499)
0.1 3.9 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1 1.0 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 1.7 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 3.4 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 0.6 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 3.8 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 1.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.4 GO:0032261 purine nucleotide salvage(GO:0032261)
0.1 0.4 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 1.4 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.1 1.3 GO:0019228 neuronal action potential(GO:0019228)
0.1 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.9 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.1 0.4 GO:2001286 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 3.4 GO:0006414 translational elongation(GO:0006414)
0.1 1.1 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.5 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.5 GO:0071451 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 1.2 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.9 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 1.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.5 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 1.1 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.6 GO:0042407 cristae formation(GO:0042407)
0.0 1.3 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 1.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 3.6 GO:0031101 fin regeneration(GO:0031101)
0.0 1.9 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 0.3 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.2 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.3 GO:0050890 cognition(GO:0050890)
0.0 0.6 GO:0034453 microtubule anchoring(GO:0034453)
0.0 1.0 GO:0045332 phospholipid translocation(GO:0045332)
0.0 1.2 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 3.4 GO:0006909 phagocytosis(GO:0006909)
0.0 0.3 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 1.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 5.7 GO:0006813 potassium ion transport(GO:0006813)
0.0 2.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.2 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.9 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.7 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 1.8 GO:0001945 lymph vessel development(GO:0001945)
0.0 2.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.5 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 1.7 GO:0051260 protein homooligomerization(GO:0051260)
0.0 2.3 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.7 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 4.4 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.0 1.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 3.4 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 1.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.5 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 1.6 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 1.9 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.0 0.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.5 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.6 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.4 GO:0019319 hexose biosynthetic process(GO:0019319)
0.0 2.3 GO:0050770 regulation of axonogenesis(GO:0050770)
0.0 0.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.4 GO:0039020 pronephric nephron tubule development(GO:0039020)
0.0 2.1 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.0 0.4 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 1.6 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.2 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.9 GO:0051607 defense response to virus(GO:0051607)
0.0 0.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 1.2 GO:0006979 response to oxidative stress(GO:0006979)
0.0 0.8 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 1.1 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.4 GO:0042584 chromaffin granule membrane(GO:0042584)
0.6 4.0 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.5 3.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.5 1.5 GO:0032997 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.5 3.4 GO:0043194 axon initial segment(GO:0043194)
0.5 4.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.3 3.6 GO:0045095 keratin filament(GO:0045095)
0.3 2.5 GO:0035060 brahma complex(GO:0035060)
0.3 1.2 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 3.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.7 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.9 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 3.8 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 2.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.1 2.2 GO:0032039 integrator complex(GO:0032039)
0.1 0.4 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.1 9.4 GO:0005882 intermediate filament(GO:0005882)
0.1 2.8 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.1 2.1 GO:0005686 U2 snRNP(GO:0005686) U12-type spliceosomal complex(GO:0005689)
0.1 1.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.9 GO:0035869 ciliary transition zone(GO:0035869)
0.1 0.6 GO:0061617 MICOS complex(GO:0061617)
0.0 4.1 GO:0005871 kinesin complex(GO:0005871)
0.0 0.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 3.0 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 2.3 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 1.4 GO:0030175 filopodium(GO:0030175)
0.0 4.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 4.6 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.5 GO:0030667 secretory granule membrane(GO:0030667)
0.0 3.5 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 10.3 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.9 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.4 GO:0016342 catenin complex(GO:0016342)
0.0 1.1 GO:0030427 site of polarized growth(GO:0030427)
0.0 1.7 GO:0005884 actin filament(GO:0005884)
0.0 1.4 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.9 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.0 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 1.1 GO:0005930 axoneme(GO:0005930)
0.0 1.6 GO:0005911 cell-cell junction(GO:0005911)
0.0 3.4 GO:0030424 axon(GO:0030424)
0.0 1.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 6.8 GO:0005789 endoplasmic reticulum membrane(GO:0005789)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.9 2.7 GO:0005335 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
0.6 4.9 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.5 2.0 GO:0004064 arylesterase activity(GO:0004064)
0.5 1.5 GO:0019763 immunoglobulin receptor activity(GO:0019763) IgE receptor activity(GO:0019767)
0.5 2.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.5 1.9 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.5 1.9 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.4 1.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.4 2.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.4 1.1 GO:0003913 DNA photolyase activity(GO:0003913)
0.3 1.0 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.3 1.2 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.3 0.9 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.3 3.5 GO:0005537 mannose binding(GO:0005537)
0.2 1.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.2 1.9 GO:0005113 patched binding(GO:0005113)
0.2 1.0 GO:0070412 R-SMAD binding(GO:0070412)
0.2 2.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 2.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 2.4 GO:0008061 chitin binding(GO:0008061)
0.2 3.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 2.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2 1.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 2.4 GO:0048495 Roundabout binding(GO:0048495)
0.2 3.0 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.8 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 1.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 4.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 3.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 2.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 2.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 1.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 1.3 GO:0070700 BMP receptor binding(GO:0070700)
0.1 6.2 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.6 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 3.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 7.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.9 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 4.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 1.8 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.7 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.1 0.7 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 1.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 1.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.0 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 4.3 GO:0044325 ion channel binding(GO:0044325)
0.1 0.4 GO:0004001 adenosine kinase activity(GO:0004001)
0.1 3.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 1.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 3.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 3.9 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 1.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.0 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.2 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.1 0.5 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 1.1 GO:0048185 activin binding(GO:0048185)
0.1 0.9 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 2.0 GO:0017046 peptide hormone binding(GO:0017046)
0.1 1.2 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 1.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.7 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.9 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 10.2 GO:0042802 identical protein binding(GO:0042802)
0.0 0.5 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 1.7 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.2 GO:0047192 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.5 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 1.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.3 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.3 GO:0016208 AMP binding(GO:0016208)
0.0 1.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 5.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0016408 C-acyltransferase activity(GO:0016408)
0.0 1.0 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 4.4 GO:0015293 symporter activity(GO:0015293)
0.0 2.9 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.3 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 0.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.0 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 6.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0030552 cAMP binding(GO:0030552)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 1.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 7.5 GO:0003779 actin binding(GO:0003779)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.2 2.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 2.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.6 PID RAS PATHWAY Regulation of Ras family activation
0.1 3.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 2.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 0.6 PID IL3 PATHWAY IL3-mediated signaling events
0.1 1.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.9 PID ARF 3PATHWAY Arf1 pathway
0.0 2.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.6 PID CXCR4 PATHWAY CXCR4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.3 2.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.3 4.0 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 1.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 4.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 3.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 3.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 2.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 1.8 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 0.6 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 1.3 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 1.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.7 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 2.1 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 1.0 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 2.1 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)