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PRJEB1986: zebrafish developmental stages transcriptome

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Results for atf5a+atf5b

Z-value: 0.86

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Transcription factors associated with atf5a+atf5b

Gene Symbol Gene ID Gene Info
atf5a
ENSDARG00000068096 activating transcription factor 5a
atf5b
ENSDARG00000077785 activating transcription factor 5b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
atf5adr11_v1_chr5_-_30418636_304186360.751.9e-04Click!
atf5bdr11_v1_chr15_-_17869115_17869115-0.331.6e-01Click!

Activity profile of atf5a+atf5b motif

Sorted Z-values of atf5a+atf5b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_9802998 2.73 ENSDART00000154217
tapbpl
TAP binding protein (tapasin)-like
chr15_-_39963009 2.35 ENSDART00000157388
lypc
ly6 domain containing, pigment cell
chr9_-_30190513 2.30 ENSDART00000137083
impg2a
interphotoreceptor matrix proteoglycan 2a
chr19_-_5125663 2.26 ENSDART00000005547
ENSDART00000132642
gnb3b
guanine nucleotide binding protein (G protein), beta polypeptide 3b
chr7_-_28147838 2.10 ENSDART00000158921
lmo1
LIM domain only 1
chr25_+_20216159 1.98 ENSDART00000048642
tnnt2d
troponin T2d, cardiac
chr9_-_23944470 1.83 ENSDART00000138754
col6a3
collagen, type VI, alpha 3
chr4_-_16333944 1.83 ENSDART00000079523
epyc
epiphycan
chr21_-_22115136 1.77 ENSDART00000134715
ENSDART00000089246
ENSDART00000139789
elmod1
ELMO/CED-12 domain containing 1
chr18_+_7283283 1.77 ENSDART00000141493
ANO2 (1 of many)
si:ch73-86n2.1
chr5_-_64213253 1.75 ENSDART00000171711
gpsm1a
G protein signaling modulator 1a
chr3_+_29714775 1.74 ENSDART00000041388
cacng2a
calcium channel, voltage-dependent, gamma subunit 2a
chr5_-_33215261 1.54 ENSDART00000097935
ENSDART00000134777
si:dkey-226m8.10
si:dkey-226m8.10
chr9_-_27648683 1.54 ENSDART00000017292
stxbp5l
syntaxin binding protein 5-like
chr23_-_26521970 1.53 ENSDART00000143712
si:dkey-205h13.1
si:dkey-205h13.1
chr4_-_72609735 1.49 ENSDART00000174299
ENSDART00000159227
si:cabz01054394.6
si:cabz01054394.6
chr19_-_21832441 1.45 ENSDART00000151272
ENSDART00000151442
ENSDART00000150168
ENSDART00000148797
ENSDART00000128196
ENSDART00000149259
ENSDART00000052556
ENSDART00000149658
ENSDART00000149639
ENSDART00000148424
mbpa
myelin basic protein a
chr3_-_30123113 1.41 ENSDART00000153562
ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr11_+_25472758 1.40 ENSDART00000011178
opn1sw2
opsin 1 (cone pigments), short-wave-sensitive 2
chr18_-_38088099 1.39 ENSDART00000146120
luzp2
leucine zipper protein 2
chr18_+_22793465 1.35 ENSDART00000149685
gnao1a
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a
chr18_-_38087875 1.33 ENSDART00000111301
luzp2
leucine zipper protein 2
chr17_-_37214196 1.28 ENSDART00000128715
kif3cb
kinesin family member 3Cb
chr20_+_15982482 1.20 ENSDART00000020999
angptl1a
angiopoietin-like 1a
chr4_-_16334362 1.19 ENSDART00000101461
epyc
epiphycan
chr16_+_10918252 1.18 ENSDART00000172949
pou2f2a
POU class 2 homeobox 2a
chr24_+_34606966 1.14 ENSDART00000105477
lrrtm2
leucine rich repeat transmembrane neuronal 2
chr17_-_20711735 1.14 ENSDART00000150056
ank3b
ankyrin 3b
chr6_+_36807861 1.14 ENSDART00000161708
si:ch73-29l19.1
si:ch73-29l19.1
chr1_+_32521469 1.14 ENSDART00000113818
ENSDART00000152580
nlgn4a
neuroligin 4a
chr5_+_25952340 1.10 ENSDART00000147188
trpm3
transient receptor potential cation channel, subfamily M, member 3
chr14_-_44841335 1.07 ENSDART00000173011
GRXCR1
si:dkey-109l4.6
chr9_-_6372535 1.06 ENSDART00000149189
ecrg4a
esophageal cancer related gene 4a
chr6_-_52400896 1.06 ENSDART00000187624
mmp24
matrix metallopeptidase 24
chr10_+_29199172 1.05 ENSDART00000148828
picalma
phosphatidylinositol binding clathrin assembly protein a
chr5_+_42467867 1.02 ENSDART00000172028
pimr58
Pim proto-oncogene, serine/threonine kinase, related 58
chr21_+_13908858 1.01 ENSDART00000148199
stxbp1a
syntaxin binding protein 1a
chr18_+_28988373 1.01 ENSDART00000018685
syt9a
synaptotagmin IXa
chr23_-_35069805 1.00 ENSDART00000087219
BX294434.1

chr21_+_13353263 0.99 ENSDART00000114677
si:ch73-62l21.1
si:ch73-62l21.1
chr11_+_26476153 0.97 ENSDART00000103507
unm_sa1614
un-named sa1614
chr5_+_45140914 0.96 ENSDART00000172702
smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr5_-_26187097 0.94 ENSDART00000137027
ccdc125
coiled-coil domain containing 125
chr11_-_44030962 0.94 ENSDART00000171910
FP016005.1

chr9_-_35069645 0.93 ENSDART00000122679
ENSDART00000077908
ENSDART00000077894
ENSDART00000125536
appb
amyloid beta (A4) precursor protein b
chr24_-_23671383 0.89 ENSDART00000144193
hnf4g
hepatocyte nuclear factor 4, gamma
chr16_-_24135508 0.88 ENSDART00000171819
ENSDART00000103176
bcam
basal cell adhesion molecule (Lutheran blood group)
chr2_-_34555945 0.88 ENSDART00000056671
brinp2
bone morphogenetic protein/retinoic acid inducible neural-specific 2
chr15_+_15390882 0.88 ENSDART00000062024
ca4b
carbonic anhydrase IV b
chr16_-_24518027 0.87 ENSDART00000134120
ENSDART00000143761
cadm4
cell adhesion molecule 4
chr24_-_11309477 0.86 ENSDART00000137257
myrip
myosin VIIA and Rab interacting protein
chr14_+_14225048 0.85 ENSDART00000168749
nlgn3a
neuroligin 3a
chr16_+_10346277 0.82 ENSDART00000081092
si:dkeyp-77h1.4
si:dkeyp-77h1.4
chr14_-_44841503 0.82 ENSDART00000179114
GRXCR1
si:dkey-109l4.6
chr21_-_17482465 0.80 ENSDART00000004548
barhl1b
BarH-like homeobox 1b
chr13_+_28854438 0.78 ENSDART00000193407
ENSDART00000189554
CU639469.1

chr24_+_25069609 0.77 ENSDART00000115165
amer2
APC membrane recruitment protein 2
chr6_-_15639087 0.77 ENSDART00000128940
ENSDART00000183092
mlpha
melanophilin a
chr3_-_16227683 0.77 ENSDART00000111707
cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr18_+_22793743 0.77 ENSDART00000150106
gnao1a
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a
chr2_+_30916188 0.75 ENSDART00000137012
myom1a
myomesin 1a (skelemin)
chr13_-_21739142 0.73 ENSDART00000078460
si:dkey-191g9.5
si:dkey-191g9.5
chr10_-_7785930 0.73 ENSDART00000043961
ENSDART00000111058
mpx
myeloid-specific peroxidase
chr7_-_20758825 0.73 ENSDART00000156717
ENSDART00000182629
ENSDART00000179801
chd3
chromodomain helicase DNA binding protein 3
chr24_-_20321012 0.73 ENSDART00000163683
map3k20
mitogen-activated protein kinase kinase kinase 20
chr5_-_19052184 0.72 ENSDART00000133330
fam214b
family with sequence similarity 214, member B
chr24_-_23671709 0.71 ENSDART00000164750
hnf4g
hepatocyte nuclear factor 4, gamma
chr22_-_13165186 0.71 ENSDART00000105762
ahr2
aryl hydrocarbon receptor 2
chr24_+_35947077 0.71 ENSDART00000173406
obscnb
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b
chr12_+_8373525 0.71 ENSDART00000152180
arid5b
AT-rich interaction domain 5B
chr16_+_25259313 0.71 ENSDART00000058938
fbxo32
F-box protein 32
chr9_-_19699728 0.70 ENSDART00000166780
si:ch211-141e20.2
si:ch211-141e20.2
chr25_+_11281970 0.69 ENSDART00000180094
AKAP13
si:dkey-187e18.1
chr7_+_31879649 0.69 ENSDART00000099789
mybpc3
myosin binding protein C, cardiac
chr13_-_33007781 0.68 ENSDART00000183671
ENSDART00000179859
rbm25a
RNA binding motif protein 25a
chr19_+_32553874 0.65 ENSDART00000078197
heyl
hes-related family bHLH transcription factor with YRPW motif-like
chr19_-_46777963 0.65 ENSDART00000046857
abrab
actin binding Rho activating protein b
chr3_-_16227490 0.62 ENSDART00000057159
ENSDART00000130611
ENSDART00000012835
cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr3_+_26081343 0.61 ENSDART00000134647
atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr13_-_35051897 0.61 ENSDART00000129559
btbd3b
BTB (POZ) domain containing 3b
chr14_-_2209742 0.61 ENSDART00000054889
pcdh2ab5
protocadherin 2 alpha b 5
chr14_+_14224730 0.59 ENSDART00000180112
ENSDART00000184891
ENSDART00000174760
nlgn3a
neuroligin 3a
chr3_-_26341959 0.59 ENSDART00000169344
ENSDART00000142878
ENSDART00000087196
zgc:153240
zgc:153240
chr6_-_39765546 0.58 ENSDART00000185767
pfkmb
phosphofructokinase, muscle b
chr1_+_54626491 0.57 ENSDART00000136063
si:ch211-202h22.9
si:ch211-202h22.9
chr18_+_5213338 0.56 ENSDART00000033574
slc24a5
solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
chr24_-_20320480 0.56 ENSDART00000137366
map3k20
mitogen-activated protein kinase kinase kinase 20
chr11_-_37880492 0.54 ENSDART00000102868
etnk2
ethanolamine kinase 2
chr3_+_45758760 0.51 ENSDART00000076007
gper1
G protein-coupled estrogen receptor 1
chr15_+_7054754 0.49 ENSDART00000149800
foxl2a
forkhead box L2a
chr17_+_38476300 0.48 ENSDART00000123298
stard9
StAR-related lipid transfer (START) domain containing 9
chr19_+_30662529 0.48 ENSDART00000175662
fam49al
family with sequence similarity 49, member A-like
chr16_+_29303971 0.48 ENSDART00000087149
hapln2
hyaluronan and proteoglycan link protein 2
chr14_-_24110707 0.48 ENSDART00000133522
ENSDART00000123152
cpeb4a
cytoplasmic polyadenylation element binding protein 4a
chr25_-_16832705 0.48 ENSDART00000171336
ENSDART00000189396
dyrk4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr17_-_29902187 0.47 ENSDART00000009104
esrrb
estrogen-related receptor beta
chr5_-_40178092 0.47 ENSDART00000146664
wdfy3
WD repeat and FYVE domain containing 3
chr20_+_27194833 0.46 ENSDART00000150072
si:dkey-85n7.8
si:dkey-85n7.8
chr12_-_31995840 0.46 ENSDART00000112881
grin2cb
glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb
chr9_+_32930622 0.45 ENSDART00000100928
cnga4
cyclic nucleotide gated channel alpha 4
chr13_+_41819817 0.45 ENSDART00000185778
CABZ01066611.1

chr4_+_5180650 0.45 ENSDART00000067390
fgf6b
fibroblast growth factor 6b
chr25_-_27541288 0.44 ENSDART00000187245
spam1
sperm adhesion molecule 1
chr23_+_42652877 0.44 ENSDART00000035654
cyp2ae1
cytochrome P450, family 2, subfamily AE, polypeptide 1
chr3_-_37476278 0.44 ENSDART00000083442
si:ch211-278a6.1
si:ch211-278a6.1
chr8_+_26125218 0.44 ENSDART00000145095
celsr3
cadherin, EGF LAG seven-pass G-type receptor 3
chr7_+_26138240 0.44 ENSDART00000193750
ENSDART00000184942
nat16
N-acetyltransferase 16
chr2_+_33541928 0.42 ENSDART00000162852
BX548164.1

chr20_+_27240388 0.42 ENSDART00000123950
si:dkey-85n7.6
si:dkey-85n7.6
chr23_-_31506854 0.41 ENSDART00000131352
ENSDART00000138625
ENSDART00000133002
eya4
EYA transcriptional coactivator and phosphatase 4
chr15_-_4023182 0.40 ENSDART00000190195
CR626884.5

chr9_+_38962017 0.39 ENSDART00000140436
map2
microtubule-associated protein 2
chr7_-_31321027 0.39 ENSDART00000186878
CR356242.1

chr7_+_28612671 0.37 ENSDART00000019991
slc7a6os
solute carrier family 7, member 6 opposite strand
chr1_+_52130213 0.36 ENSDART00000018817
rnf11a
ring finger protein 11a
chr21_+_9997418 0.36 ENSDART00000181454
ENSDART00000171579
herc7
hect domain and RLD 7
chr5_+_22264051 0.36 ENSDART00000143314
arhgap20b
Rho GTPase activating protein 20b
chr6_+_37308716 0.36 ENSDART00000085498
ptger3
prostaglandin E receptor 3 (subtype EP3)
chr3_+_15358625 0.36 ENSDART00000143280
sh2b1
SH2B adaptor protein 1
chr6_-_13475439 0.35 ENSDART00000172318
mylkb
myosin light chain kinase b
chr3_+_22905341 0.35 ENSDART00000111435
hdac5
histone deacetylase 5
chr20_+_54336137 0.35 ENSDART00000113792
cipcb
CLOCK-interacting pacemaker b
chr1_+_10771457 0.35 ENSDART00000027050
ENSDART00000137185
cnga3b
cyclic nucleotide gated channel alpha 3b
chr4_-_8902406 0.34 ENSDART00000192962
mpped1
metallophosphoesterase domain containing 1
chr8_+_25767610 0.34 ENSDART00000062406
cacna1sb
calcium channel, voltage-dependent, L type, alpha 1S subunit, b
chr25_+_16214854 0.34 ENSDART00000109672
ENSDART00000190093
mical2b
microtubule associated monooxygenase, calponin and LIM domain containing 2b
chr4_-_13255700 0.33 ENSDART00000162277
ENSDART00000026593
grip1
glutamate receptor interacting protein 1
chr21_+_10790680 0.33 ENSDART00000144460
znf532
zinc finger protein 532
chr16_-_44649053 0.33 ENSDART00000184807
CR925804.2

chr9_-_48701035 0.32 ENSDART00000178332
rdh1
retinol dehydrogenase 1
chr21_-_26691959 0.32 ENSDART00000149702
ENSDART00000149840
bscl2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr19_-_35596207 0.32 ENSDART00000136811
col8a2
collagen, type VIII, alpha 2
chr22_+_36656680 0.31 ENSDART00000134031
ENSDART00000056169
b3gnt7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr15_+_31515976 0.30 ENSDART00000156471
tex26
testis expressed 26
chr17_-_20849879 0.30 ENSDART00000088100
ENSDART00000149630
ank3b
ankyrin 3b
chr5_-_1047504 0.30 ENSDART00000159346
mbd2
methyl-CpG binding domain protein 2
chr23_-_27692717 0.30 ENSDART00000053878
ENSDART00000145028
IKZF4
si:dkey-166n8.9
chr1_+_16573982 0.29 ENSDART00000166317
mtus1b
microtubule associated tumor suppressor 1b
chr25_-_37465064 0.28 ENSDART00000186128
zgc:158366
zgc:158366
chr16_-_34338537 0.28 ENSDART00000142223
hivep3b
human immunodeficiency virus type I enhancer binding protein 3b
chr10_+_8534750 0.26 ENSDART00000183960
tbc1d10ab
TBC1 domain family, member 10Ab
chr3_-_46817838 0.26 ENSDART00000028610
elavl3
ELAV like neuron-specific RNA binding protein 3
chr10_-_7386475 0.25 ENSDART00000167963
nrg1
neuregulin 1
chr24_-_1341543 0.25 ENSDART00000169341
nrp1a
neuropilin 1a
chr15_-_3976035 0.25 ENSDART00000168061
si:ch73-309g22.1
si:ch73-309g22.1
chr16_-_13004166 0.24 ENSDART00000133735
cacng7b
calcium channel, voltage-dependent, gamma subunit 7b
chr21_-_38031038 0.24 ENSDART00000179483
ENSDART00000076238
rbm41
RNA binding motif protein 41
chr17_-_21793113 0.24 ENSDART00000104612
hmx3a
H6 family homeobox 3a
chr18_+_13203831 0.24 ENSDART00000032151
cotl1
coactosin-like F-actin binding protein 1
chr20_+_23676649 0.23 ENSDART00000035239
nek1
NIMA-related kinase 1
chr22_-_30935510 0.23 ENSDART00000133335
si:dkey-49n23.1
si:dkey-49n23.1
chr15_+_22267847 0.23 ENSDART00000110665
spa17
sperm autoantigenic protein 17
chr13_-_13754091 0.23 ENSDART00000131255
ky
kyphoscoliosis peptidase
chr4_+_18824959 0.23 ENSDART00000146141
ENSDART00000040424
slc26a3.1
solute carrier family 26 (anion exchanger), member 3
chr3_+_15358459 0.22 ENSDART00000141808
sh2b1
SH2B adaptor protein 1
chr11_+_5926850 0.22 ENSDART00000104364
rps15
ribosomal protein S15
chr24_+_7782313 0.21 ENSDART00000111090
ptprh
protein tyrosine phosphatase, receptor type, h
chr20_+_44582318 0.21 ENSDART00000149000
ENSDART00000149775
ENSDART00000085416
atad2b
ATPase family, AAA domain containing 2B
chr5_+_30384554 0.20 ENSDART00000135483
zgc:158412
zgc:158412
chr12_-_43435254 0.20 ENSDART00000182723
ptprea
protein tyrosine phosphatase, receptor type, E, a
chr16_+_44314097 0.20 ENSDART00000148684
dpys
dihydropyrimidinase
chr5_-_67757188 0.20 ENSDART00000167168
b4galt4
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr1_-_5745420 0.19 ENSDART00000166779
nrp2a
neuropilin 2a
chr2_-_5399437 0.18 ENSDART00000132411
si:ch1073-184j22.2
si:ch1073-184j22.2
chr15_+_3790556 0.17 ENSDART00000181467
RNF14 (1 of many)
ring finger protein 14
chr22_+_30035719 0.16 ENSDART00000192238
AL845330.1

chr5_+_22791686 0.15 ENSDART00000014806
npas2
neuronal PAS domain protein 2
chr18_-_50152689 0.14 ENSDART00000006078
loxl1
lysyl oxidase-like 1
chr5_-_1047222 0.14 ENSDART00000181112
mbd2
methyl-CpG binding domain protein 2
chr21_+_22985078 0.13 ENSDART00000156491
lpar6b
lysophosphatidic acid receptor 6b
chr7_+_25036188 0.12 ENSDART00000163957
ENSDART00000169749
sb:cb1058
sb:cb1058
chr11_-_1948784 0.12 ENSDART00000082475
nr1d4b
nuclear receptor subfamily 1, group D, member 4b
chr23_-_21758253 0.12 ENSDART00000046613
vps13d
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr1_-_16665044 0.11 ENSDART00000040434
asah1b
N-acylsphingosine amidohydrolase (acid ceramidase) 1b
chr19_+_3826782 0.11 ENSDART00000169222
oscp1a
organic solute carrier partner 1a
chr9_-_15362556 0.10 ENSDART00000191233
fn1a
fibronectin 1a
chr20_+_51478939 0.10 ENSDART00000149758
tlr5a
toll-like receptor 5a
chr3_+_18389363 0.10 ENSDART00000146114
si:ch211-139g16.8
si:ch211-139g16.8
chr8_+_35356944 0.10 ENSDART00000143243
si:dkeyp-14d3.1
si:dkeyp-14d3.1
chr1_+_16574312 0.10 ENSDART00000187067
mtus1b
microtubule associated tumor suppressor 1b
chr19_-_46088429 0.10 ENSDART00000161385
ptdss1b
phosphatidylserine synthase 1b
chr20_-_23026223 0.09 ENSDART00000015755
rasl11b
RAS-like, family 11, member B
chr14_+_8127893 0.09 ENSDART00000169091
psd2
pleckstrin and Sec7 domain containing 2
chr25_-_32751982 0.08 ENSDART00000012862
isl2a
ISL LIM homeobox 2a
chr16_+_39159752 0.08 ENSDART00000122081
sybu
syntabulin (syntaxin-interacting)
chr6_-_42971184 0.08 ENSDART00000014552
arl8ba
ADP-ribosylation factor-like 8Ba
chr1_-_37377509 0.08 ENSDART00000113542
tnip2
TNFAIP3 interacting protein 2
chr10_-_39055620 0.07 ENSDART00000187437
igsf5a
immunoglobulin superfamily, member 5a
chr23_+_2185397 0.07 ENSDART00000109373
c1qtnf7
C1q and TNF related 7
chr14_-_24110251 0.07 ENSDART00000079226
cpeb4a
cytoplasmic polyadenylation element binding protein 4a
chr1_+_41498188 0.07 ENSDART00000191934
ENSDART00000146310
dtx4
deltex 4, E3 ubiquitin ligase
chr9_+_9858935 0.06 ENSDART00000137206
si:ch1073-394i4.1
si:ch1073-394i4.1
chr5_-_48307804 0.06 ENSDART00000182831
ENSDART00000186920
ENSDART00000183585
mef2cb
myocyte enhancer factor 2cb
chr14_-_24110062 0.04 ENSDART00000177062
cpeb4a
cytoplasmic polyadenylation element binding protein 4a
chr11_+_2649664 0.04 ENSDART00000166357
si:ch211-160o17.4
si:ch211-160o17.4
chr3_+_17456428 0.04 ENSDART00000090676
ENSDART00000182082
si:ch211-210g13.5
si:ch211-210g13.5
chr4_-_62503772 0.04 ENSDART00000108891
si:dkey-165b20.1
si:dkey-165b20.1
chr3_-_46818001 0.03 ENSDART00000166505
elavl3
ELAV like neuron-specific RNA binding protein 3
chr3_-_50118140 0.03 ENSDART00000131913
hgs
hepatocyte growth factor-regulated tyrosine kinase substrate
chr22_+_3045495 0.03 ENSDART00000164061
LO017843.1

Network of associatons between targets according to the STRING database.

First level regulatory network of atf5a+atf5b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.2 2.7 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 0.8 GO:0051876 pigment granule dispersal(GO:0051876)
0.2 1.1 GO:0050951 detection of temperature stimulus(GO:0016048) sensory perception of temperature stimulus(GO:0050951)
0.2 0.5 GO:1903430 negative regulation of cell maturation(GO:1903430)
0.2 0.5 GO:0048496 maintenance of organ identity(GO:0048496)
0.2 1.0 GO:0031507 heterochromatin assembly(GO:0031507)
0.2 0.6 GO:0090076 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.1 0.9 GO:0003232 bulbus arteriosus development(GO:0003232)
0.1 0.7 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 1.4 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 2.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.4 GO:0044058 regulation of digestive system process(GO:0044058)
0.1 0.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.3 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 0.3 GO:0060959 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.1 0.7 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.1 0.7 GO:0060612 adipose tissue development(GO:0060612)
0.1 1.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.7 GO:0001541 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
0.1 0.3 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.7 GO:2000377 regulation of reactive oxygen species metabolic process(GO:2000377)
0.1 1.4 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 0.6 GO:0061620 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.3 GO:0060055 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.0 2.1 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.8 GO:0007398 ectoderm development(GO:0007398)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.4 GO:0016576 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.4 GO:0048532 anatomical structure arrangement(GO:0048532)
0.0 2.0 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 1.5 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 0.1 GO:0097264 self proteolysis(GO:0097264)
0.0 0.6 GO:0097324 melanocyte migration(GO:0097324)
0.0 1.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 1.0 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 1.1 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.4 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 1.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.3 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.1 GO:0061339 establishment of apical/basal cell polarity(GO:0035089) establishment of epithelial cell apical/basal polarity(GO:0045198) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.1 GO:0034138 toll-like receptor 2 signaling pathway(GO:0034134) toll-like receptor 3 signaling pathway(GO:0034138)
0.0 0.3 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.5 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 2.3 GO:0007623 circadian rhythm(GO:0007623)
0.0 0.7 GO:0035775 pronephric glomerulus morphogenesis(GO:0035775)
0.0 1.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 1.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0060074 synapse maturation(GO:0060074)
0.0 0.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.6 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.2 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968) neurotransmitter receptor internalization(GO:0099590)
0.0 3.7 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.2 GO:0009651 response to salt stress(GO:0009651)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.9 GO:0008593 regulation of Notch signaling pathway(GO:0008593)
0.0 2.6 GO:0007601 visual perception(GO:0007601)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 1.4 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 0.9 GO:2000146 negative regulation of cell motility(GO:2000146)
0.0 0.2 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 1.6 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.3 GO:0072114 pronephros morphogenesis(GO:0072114)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.2 1.5 GO:0016586 RSC complex(GO:0016586)
0.2 0.6 GO:0031673 H zone(GO:0031673)
0.1 1.0 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 1.0 GO:0031045 dense core granule(GO:0031045)
0.1 1.5 GO:0043209 myelin sheath(GO:0043209)
0.1 1.5 GO:0031430 M band(GO:0031430)
0.1 4.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.6 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.7 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 3.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.0 GO:0005861 troponin complex(GO:0005861)
0.0 0.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 1.0 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.5 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 1.8 GO:0005871 kinesin complex(GO:0005871)
0.0 1.5 GO:0031201 SNARE complex(GO:0031201)
0.0 1.8 GO:0005581 collagen trimer(GO:0005581)
0.0 1.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.0 GO:0030141 secretory granule(GO:0030141)
0.0 0.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0031852 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 2.0 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.2 2.3 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.5 GO:0045159 myosin II binding(GO:0045159)
0.1 1.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 2.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.6 GO:0017022 myosin binding(GO:0017022)
0.1 0.5 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.8 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 1.5 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 1.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.3 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.1 1.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 2.1 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 0.6 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.4 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 1.1 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 2.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 2.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.5 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 5.8 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 1.8 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0001948 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.0 0.7 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.7 PID FOXO PATHWAY FoxO family signaling
0.0 1.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 3.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.4 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA