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PRJEB1986: zebrafish developmental stages transcriptome

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Results for bbx

Z-value: 1.34

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Transcription factors associated with bbx

Gene Symbol Gene ID Gene Info
bbx
ENSDARG00000012699 BBX high mobility group box domain containing

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
bbxdr11_v1_chr10_-_28525611_28525611-0.923.0e-08Click!

Activity profile of bbx motif

Sorted Z-values of bbx motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_12031958 4.51 ENSDART00000044154
tnnt2c
troponin T2c, cardiac
chr21_+_21263988 3.63 ENSDART00000089651
ENSDART00000108978
ccdc61
coiled-coil domain containing 61
chr7_+_72003301 3.54 ENSDART00000012918
ENSDART00000182268
ENSDART00000185750
psmd9
proteasome 26S subunit, non-ATPase 9
chr1_+_29858032 3.31 ENSDART00000054066
zic2b
zic family member 2 (odd-paired homolog, Drosophila) b
chr12_-_18568834 3.16 ENSDART00000039693
pgp
phosphoglycolate phosphatase
chr8_+_28593707 3.03 ENSDART00000097213
tcf15
transcription factor 15
chr23_+_19670085 2.88 ENSDART00000031872
kctd6b
potassium channel tetramerization domain containing 6b
chr20_-_25626693 2.83 ENSDART00000132247
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr20_-_25626198 2.62 ENSDART00000126716
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr17_+_24718272 2.43 ENSDART00000007271
mtfr1l
mitochondrial fission regulator 1-like
chr14_-_4177311 2.41 ENSDART00000128129
si:dkey-185e18.7
si:dkey-185e18.7
chr20_-_25626428 2.40 ENSDART00000136475
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr25_+_16646113 2.33 ENSDART00000110426
cecr2
cat eye syndrome chromosome region, candidate 2
chr25_-_16076257 2.23 ENSDART00000140780
ovch2
ovochymase 2
chr10_-_29892486 2.17 ENSDART00000099983
bsx
brain-specific homeobox
chr8_-_14091886 2.11 ENSDART00000137857
si:ch211-229n2.7
si:ch211-229n2.7
chr9_-_30555725 2.07 ENSDART00000079222
chaf1b
chromatin assembly factor 1, subunit B
chr5_+_69733096 2.05 ENSDART00000169013
arl6ip4
ADP-ribosylation factor-like 6 interacting protein 4
chr9_-_15424639 2.03 ENSDART00000124346
fn1a
fibronectin 1a
chr15_-_4596623 2.00 ENSDART00000132227
eif4h
eukaryotic translation initiation factor 4h
chr7_+_24729558 1.98 ENSDART00000111542
ENSDART00000170100
shroom4
shroom family member 4
chr24_-_9002038 1.86 ENSDART00000066783
ENSDART00000150185
mppe1
metallophosphoesterase 1
chr3_+_13862753 1.84 ENSDART00000168315
ilf3b
interleukin enhancer binding factor 3b
chr2_-_32237916 1.74 ENSDART00000141418
fam49ba
family with sequence similarity 49, member Ba
chr17_+_8799451 1.73 ENSDART00000189814
ENSDART00000191577
tonsl
tonsoku-like, DNA repair protein
chr11_-_7410537 1.71 ENSDART00000009859
adgrl4
adhesion G protein-coupled receptor L4
chr8_+_52701811 1.69 ENSDART00000179692
bcl2l16
BCL2 like 16
chr17_+_8799661 1.68 ENSDART00000105326
tonsl
tonsoku-like, DNA repair protein
chr8_-_40205712 1.67 ENSDART00000158927
anapc5
anaphase promoting complex subunit 5
chr25_+_16880990 1.66 ENSDART00000020259
zgc:77158
zgc:77158
chr15_+_16886196 1.63 ENSDART00000139296
ENSDART00000049196
gdpd1
glycerophosphodiester phosphodiesterase domain containing 1
chr24_+_41989108 1.62 ENSDART00000169725
zbtb14
zinc finger and BTB domain containing 14
chr7_+_50395856 1.57 ENSDART00000032324
hddc3
HD domain containing 3
chr6_+_36839509 1.53 ENSDART00000190605
ENSDART00000104160
zgc:110788
zgc:110788
chr12_-_17686404 1.52 ENSDART00000079065
ccz1
CCZ1 homolog, vacuolar protein trafficking and biogenesis associated
chr15_-_35212462 1.51 ENSDART00000043960
agfg1a
ArfGAP with FG repeats 1a
chr11_+_2416064 1.51 ENSDART00000067117
ube2v1
ubiquitin-conjugating enzyme E2 variant 1
chr16_-_27566552 1.47 ENSDART00000142102
zgc:153215
zgc:153215
chr13_-_24669258 1.42 ENSDART00000000831
znf511
zinc finger protein 511
chr7_+_42460302 1.42 ENSDART00000004120
adamts18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr3_+_54761569 1.40 ENSDART00000135913
ENSDART00000180983
si:ch211-74m13.1
si:ch211-74m13.1
chr6_+_30430591 1.38 ENSDART00000108943
shroom2a
shroom family member 2a
chr12_-_33770299 1.37 ENSDART00000189849
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr11_-_12104917 1.36 ENSDART00000136108
mrpl45
mitochondrial ribosomal protein L45
chr6_+_37301341 1.33 ENSDART00000104180
zranb2
zinc finger, RAN-binding domain containing 2
chr18_+_6857071 1.33 ENSDART00000018735
ENSDART00000181969
dnaja2l
DnaJ (Hsp40) homolog, subfamily A, member 2, like
chr9_+_24106469 1.32 ENSDART00000039295
lrrfip1a
leucine rich repeat (in FLII) interacting protein 1a
chr24_-_20926812 1.31 ENSDART00000130958
ccdc58
coiled-coil domain containing 58
chr19_+_10860485 1.28 ENSDART00000169962
si:ch73-347e22.4
si:ch73-347e22.4
chr23_+_35504824 1.25 ENSDART00000082647
ENSDART00000159218
acp1
acid phosphatase 1
chr19_-_438337 1.25 ENSDART00000127985
MTERF1
mitochondrial transcription termination factor 1
chr7_+_36898850 1.24 ENSDART00000113342
tox3
TOX high mobility group box family member 3
chr14_+_36223097 1.21 ENSDART00000186872
pitx2
paired-like homeodomain 2
chr1_+_35956435 1.20 ENSDART00000085021
ENSDART00000148505
mmaa
methylmalonic aciduria (cobalamin deficiency) cblA type
chr6_+_6780873 1.20 ENSDART00000011865
sec23b
Sec23 homolog B, COPII coat complex component
chr15_+_23528310 1.19 ENSDART00000152523
si:dkey-182i3.8
si:dkey-182i3.8
chr8_+_31016180 1.18 ENSDART00000130870
ENSDART00000143604
odf2b
outer dense fiber of sperm tails 2b
chr16_-_47427016 1.18 ENSDART00000074575
sept7b
septin 7b
chr16_+_32014552 1.15 ENSDART00000047570
mboat7
membrane bound O-acyltransferase domain containing 7
chr13_+_18507592 1.15 ENSDART00000142622
si:ch211-198a12.6
si:ch211-198a12.6
chr21_-_25416391 1.12 ENSDART00000114081
sms
spermine synthase
chr8_+_21114338 1.12 ENSDART00000002186
uck2a
uridine-cytidine kinase 2a
chr15_+_36310442 1.12 ENSDART00000154678
gmnc
geminin coiled-coil domain containing
chr1_-_7673376 1.11 ENSDART00000013264
arglu1b
arginine and glutamate rich 1b
chr1_+_12767318 1.10 ENSDART00000162652
pcdh10a
protocadherin 10a
chr4_+_5215950 1.09 ENSDART00000140613
galnt8b.2
polypeptide N-acetylgalactosaminyltransferase 8b, tandem duplicate 2
chr23_-_30781875 1.09 ENSDART00000114628
ENSDART00000180949
ENSDART00000191313
myt1a
myelin transcription factor 1a
chr20_-_20248408 1.07 ENSDART00000183234
ppp2r5ea
protein phosphatase 2, regulatory subunit B', epsilon isoform a
chr6_-_43922813 1.06 ENSDART00000123341
prok2
prokineticin 2
chr11_-_23322182 1.06 ENSDART00000111289
kiss1
KiSS-1 metastasis-suppressor
chr2_-_22659450 1.04 ENSDART00000115025
thap4
THAP domain containing 4
chr17_+_43867889 1.03 ENSDART00000132673
ENSDART00000167214
zgc:66313
zgc:66313
chr1_+_55643198 1.01 ENSDART00000060693
adgre7
adhesion G protein-coupled receptor E7
chr5_+_36650096 1.00 ENSDART00000111414
alkbh6
alkB homolog 6
chr12_+_27156943 1.00 ENSDART00000153030
ENSDART00000001737
skap1
src kinase associated phosphoprotein 1
chr21_+_38732945 1.00 ENSDART00000076157
rab24
RAB24, member RAS oncogene family
chr23_+_17512037 0.99 ENSDART00000054738
gid8b
GID complex subunit 8 homolog b (S. cerevisiae)
chr22_+_9939901 0.98 ENSDART00000169777
ENSDART00000081420
zgc:171686
zgc:171686
chr1_-_28831848 0.97 ENSDART00000148536
GK3P
zgc:172295
chr20_+_25626479 0.97 ENSDART00000143883
ppat
phosphoribosyl pyrophosphate amidotransferase
chr21_+_21709204 0.96 ENSDART00000137478
or125-1
odorant receptor, family E, subfamily 125, member 1
chr11_-_27501027 0.95 ENSDART00000065889
wnt7aa
wingless-type MMTV integration site family, member 7Aa
chr8_+_23784471 0.94 ENSDART00000189457
si:ch211-163l21.8
si:ch211-163l21.8
chr13_-_7233811 0.94 ENSDART00000162026
ninl
ninein-like
chr14_+_36246726 0.90 ENSDART00000105602
elovl6
ELOVL fatty acid elongase 6
chr14_-_29826659 0.89 ENSDART00000138413
sorbs2b
sorbin and SH3 domain containing 2b
chr23_-_30781510 0.85 ENSDART00000183364
myt1a
myelin transcription factor 1a
chr12_-_9700605 0.83 ENSDART00000161063
heatr1
HEAT repeat containing 1
chr6_+_14980761 0.82 ENSDART00000087782
mrps9
mitochondrial ribosomal protein S9
chr10_-_43771447 0.81 ENSDART00000052307
arrdc3b
arrestin domain containing 3b
chr18_-_17724295 0.80 ENSDART00000121553
fam192a
family with sequence similarity 192, member A
chr15_-_31419805 0.80 ENSDART00000060111
or111-11
odorant receptor, family D, subfamily 111, member 11
chr18_-_26510545 0.80 ENSDART00000135133
FRMD5
si:ch211-69m14.1
chr3_-_34816893 0.78 ENSDART00000084448
ENSDART00000154696
psmd11a
proteasome 26S subunit, non-ATPase 11a
chr25_+_23591990 0.78 ENSDART00000151938
ENSDART00000089199
cpt1ab
carnitine palmitoyltransferase 1Ab (liver)
chr16_-_24195252 0.78 ENSDART00000136205
ENSDART00000048599
ENSDART00000161547
rps19
ribosomal protein S19
chr1_-_45039726 0.75 ENSDART00000186188
smu1b
SMU1, DNA replication regulator and spliceosomal factor b
chr4_+_16323970 0.75 ENSDART00000190651
BX322608.1

chr1_+_2431956 0.74 ENSDART00000183832
farp1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr11_-_18323059 0.71 ENSDART00000182590
SFMBT1
Scm like with four mbt domains 1
chr1_+_19535144 0.71 ENSDART00000103089
si:dkey-245p14.4
si:dkey-245p14.4
chr4_+_60296027 0.69 ENSDART00000172479
si:dkey-248e17.5
si:dkey-248e17.5
chr18_+_26899316 0.69 ENSDART00000050230
tspan3a
tetraspanin 3a
chr9_+_48755638 0.68 ENSDART00000047401
abcb11a
ATP-binding cassette, sub-family B (MDR/TAP), member 11a
chr12_-_31484677 0.67 ENSDART00000066578
tectb
tectorin beta
chr5_+_37744625 0.65 ENSDART00000014031
dpf2
D4, zinc and double PHD fingers family 2
chr21_+_29077509 0.62 ENSDART00000128561
ecscr
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr17_+_23549117 0.61 ENSDART00000063953
zgc:65997
zgc:65997
chr4_+_47636303 0.60 ENSDART00000167272
ENSDART00000166961
BX324142.1

chr16_-_30826712 0.59 ENSDART00000122474
ptk2ab
protein tyrosine kinase 2ab
chr8_-_22157301 0.57 ENSDART00000158383
nphp4
nephronophthisis 4
chr6_-_40921412 0.57 ENSDART00000076097
ENSDART00000188364
sfi1
SFI1 centrin binding protein
chr1_-_46244523 0.56 ENSDART00000143908
si:ch211-138g9.3
si:ch211-138g9.3
chr19_+_33093395 0.55 ENSDART00000019459
fam91a1
family with sequence similarity 91, member A1
chr1_+_23784905 0.55 ENSDART00000171951
ENSDART00000188521
ENSDART00000183029
ENSDART00000187183
slit2
slit homolog 2 (Drosophila)
chr21_-_22647695 0.54 ENSDART00000187553
gig2l
grass carp reovirus (GCRV)-induced gene 2l
chr25_-_12730260 0.53 ENSDART00000171834
klhdc4
kelch domain containing 4
chr10_-_34107919 0.51 ENSDART00000167428
ENSDART00000145279
pimr144
pimr146
Pim proto-oncogene, serine/threonine kinase, related 144
Pim proto-oncogene, serine/threonine kinase, related 146
chr8_+_23034718 0.51 ENSDART00000184512
ythdf1
YTH N(6)-methyladenosine RNA binding protein 1
chr3_-_37759969 0.50 ENSDART00000151105
ENSDART00000151208
si:dkey-260c8.6
si:dkey-260c8.6
chr2_-_10188598 0.49 ENSDART00000189122
dmbx1a
diencephalon/mesencephalon homeobox 1a
chr16_-_13622794 0.48 ENSDART00000146953
si:dkeyp-69b9.6
si:dkeyp-69b9.6
chr7_-_50395395 0.48 ENSDART00000065868
vps33b
vacuolar protein sorting 33B
chr6_-_35052388 0.46 ENSDART00000181000
ENSDART00000170116
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr25_+_22107643 0.46 ENSDART00000089680
sigirr
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr4_-_5595237 0.44 ENSDART00000109854
vegfab
vascular endothelial growth factor Ab
chr1_-_9104631 0.44 ENSDART00000146642
si:ch211-14k19.8
si:ch211-14k19.8
chr15_-_5222924 0.44 ENSDART00000128924
or128-4
odorant receptor, family E, subfamily 128, member 4
chr4_+_47768097 0.43 ENSDART00000192738
BX324142.2

chr19_+_33093577 0.43 ENSDART00000180317
fam91a1
family with sequence similarity 91, member A1
chr17_-_8656155 0.41 ENSDART00000148990
ctbp2a
C-terminal binding protein 2a
chr7_+_10701770 0.41 ENSDART00000167323
arnt2
aryl-hydrocarbon receptor nuclear translocator 2
chr16_-_45235947 0.41 ENSDART00000164436
si:dkey-33i11.4
si:dkey-33i11.4
chr16_+_16977786 0.41 ENSDART00000043173
ENSDART00000132150
rpl18
ribosomal protein L18
chr14_+_21005372 0.40 ENSDART00000170638
pimr195
Pim proto-oncogene, serine/threonine kinase, related 195
chr13_+_6086730 0.39 ENSDART00000049328
fam120b
family with sequence similarity 120B
chr8_+_20438884 0.39 ENSDART00000016422
ENSDART00000133794
mknk2b
MAP kinase interacting serine/threonine kinase 2b
chr15_-_1022436 0.38 ENSDART00000156003
znf1010
zinc finger protein 1010
chr14_-_30808174 0.37 ENSDART00000173262
prss23
protease, serine, 23
chr2_+_19633493 0.36 ENSDART00000147989
pimr54
Pim proto-oncogene, serine/threonine kinase, related 54
chr16_-_12291045 0.35 ENSDART00000185447
CR388102.1

chr3_-_12026741 0.34 ENSDART00000132238
cfap70
cilia and flagella associated protein 70
chr7_-_50395059 0.34 ENSDART00000191150
vps33b
vacuolar protein sorting 33B
chr8_+_20951590 0.33 ENSDART00000138728
si:dkeyp-82a1.1
si:dkeyp-82a1.1
chr16_+_16978424 0.32 ENSDART00000143128
rpl18
ribosomal protein L18
chr18_+_17493859 0.27 ENSDART00000090754
si:dkey-102f14.5
si:dkey-102f14.5
chr10_-_42751641 0.25 ENSDART00000182734
ENSDART00000113926
zgc:100918
zgc:100918
chr11_+_10548171 0.25 ENSDART00000191497
b3gnt5a
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr22_+_35930526 0.24 ENSDART00000169242
LO016987.1

chr8_+_3431671 0.21 ENSDART00000017850
ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr23_+_2703044 0.20 ENSDART00000182512
ENSDART00000105286
ncoa6
nuclear receptor coactivator 6
chr23_-_18381361 0.18 ENSDART00000016891
hsd17b10
hydroxysteroid (17-beta) dehydrogenase 10
chr22_+_19230434 0.18 ENSDART00000132929
si:dkey-21e2.8
si:dkey-21e2.8
chr17_-_24439672 0.16 ENSDART00000155020
wdpcp
WD repeat containing planar cell polarity effector
chr13_-_50565338 0.15 ENSDART00000062684
blnk
B cell linker
chr1_+_55583116 0.15 ENSDART00000152163
adgre19
adhesion G protein-coupled receptor E19
chr13_-_23095006 0.14 ENSDART00000089242
kif1bp
kif1 binding protein
chr6_-_54816567 0.14 ENSDART00000150079
tnni1b
troponin I type 1b (skeletal, slow)
chr25_-_16070806 0.13 ENSDART00000162645
CR759887.3

chr12_+_23812530 0.12 ENSDART00000066331
svila
supervillin a
chr6_-_19042294 0.09 ENSDART00000159461
si:rp71-81e14.2
si:rp71-81e14.2
chr19_+_43341424 0.09 ENSDART00000134815
sesn2
sestrin 2
chr1_+_55535827 0.07 ENSDART00000152784
adgre16
adhesion G protein-coupled receptor E16
chr7_-_1163829 0.07 ENSDART00000181937
CT030017.1

chr20_+_3934516 0.07 ENSDART00000165732
clec11a
C-type lectin domain containing 11A
chr15_+_44201056 0.06 ENSDART00000162433
ENSDART00000148336
CU655961.4

chr4_+_76442674 0.06 ENSDART00000164825
si:dkey-16p6.1
si:dkey-16p6.1
chr3_+_32553714 0.04 ENSDART00000165638
pax10
paired box 10
chr2_-_41518340 0.02 ENSDART00000130830
otomp
otolith matrix protein
chr9_+_19623363 0.01 ENSDART00000142471
ENSDART00000147662
ENSDART00000136053
pdxka
pyridoxal (pyridoxine, vitamin B6) kinase a
chr1_+_55563532 0.00 ENSDART00000152549
adgre15
adhesion G protein-coupled receptor E15
chr13_+_23095228 0.00 ENSDART00000189068
ENSDART00000188624
pik3ap1
phosphoinositide-3-kinase adaptor protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of bbx

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 1.6 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.9 8.8 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.8 3.2 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.5 3.3 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.4 2.1 GO:0070292 N-acylphosphatidylethanolamine metabolic process(GO:0070292)
0.3 2.2 GO:0021982 pineal gland development(GO:0021982)
0.3 2.0 GO:0045198 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319) acute-phase response(GO:0006953) establishment of epithelial cell apical/basal polarity(GO:0045198)
0.3 1.2 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.3 4.3 GO:0043248 proteasome assembly(GO:0043248)
0.3 2.0 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.3 1.4 GO:0010719 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.2 1.2 GO:0061072 iris morphogenesis(GO:0061072)
0.2 1.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.2 0.9 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.2 0.5 GO:0007414 axonal defasciculation(GO:0007414)
0.2 0.7 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.2 3.4 GO:0031297 replication fork processing(GO:0031297)
0.2 1.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 1.1 GO:0044211 CTP salvage(GO:0044211)
0.1 0.8 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 0.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 3.6 GO:0098534 centriole assembly(GO:0098534)
0.1 1.4 GO:0008105 asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.1 0.9 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.1 1.7 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 1.1 GO:0030431 sleep(GO:0030431)
0.1 1.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.8 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.1 0.8 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 1.5 GO:0006301 postreplication repair(GO:0006301)
0.1 4.7 GO:0060048 cardiac muscle contraction(GO:0060048)
0.1 1.9 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.6 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.1 1.1 GO:0097324 melanocyte migration(GO:0097324)
0.1 0.4 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.1 0.6 GO:0070309 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.1 2.0 GO:0000266 mitochondrial fission(GO:0000266)
0.1 1.7 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.1 1.1 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 1.1 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.0 0.9 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.5 GO:0061157 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.0 0.4 GO:0003160 endocardium morphogenesis(GO:0003160)
0.0 2.3 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.6 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.0 1.0 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.0 0.5 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.8 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 1.0 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.5 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 0.5 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 1.8 GO:0051607 defense response to virus(GO:0051607)
0.0 1.0 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 2.5 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.7 GO:0003094 glomerular filtration(GO:0003094)
0.0 1.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031) cellular response to leucine starvation(GO:1990253)
0.0 2.5 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.7 GO:0048840 otolith development(GO:0048840)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0033186 CAF-1 complex(GO:0033186)
0.5 3.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.3 3.6 GO:0034451 centriolar satellite(GO:0034451)
0.3 1.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.3 2.0 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.5 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.2 2.3 GO:0031010 ISWI-type complex(GO:0031010)
0.2 0.8 GO:0033263 CORVET complex(GO:0033263)
0.1 3.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 4.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 0.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.2 GO:0097541 axonemal basal plate(GO:0097541)
0.1 2.2 GO:0005861 troponin complex(GO:0005861)
0.0 0.8 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.6 GO:0097546 ciliary base(GO:0097546)
0.0 0.8 GO:0030686 90S preribosome(GO:0030686)
0.0 0.7 GO:0071565 nBAF complex(GO:0071565)
0.0 0.8 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 2.7 GO:0005770 late endosome(GO:0005770)
0.0 1.0 GO:0005776 autophagosome(GO:0005776)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.1 GO:0016607 nuclear speck(GO:0016607)
0.0 1.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 1.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.9 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.5 GO:0005925 focal adhesion(GO:0005925)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 7.9 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.7 2.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.4 1.3 GO:0030882 lipid antigen binding(GO:0030882)
0.3 2.0 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.3 2.0 GO:0001948 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.3 1.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 1.7 GO:0008506 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 2.1 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.2 1.8 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 0.7 GO:0015126 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.1 1.1 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.8 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.5 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.1 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.3 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 1.6 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 1.4 GO:0045159 myosin II binding(GO:0045159)
0.1 1.2 GO:0071617 lysophospholipid acyltransferase activity(GO:0071617)
0.1 1.1 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 1.9 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.9 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.8 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.5 GO:0048495 Roundabout binding(GO:0048495)
0.0 1.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 1.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 4.6 GO:0042802 identical protein binding(GO:0042802)
0.0 4.1 GO:0042393 histone binding(GO:0042393)
0.0 0.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.1 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 1.1 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 2.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.6 ST GAQ PATHWAY G alpha q Pathway
0.1 1.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.3 1.2 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 0.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 3.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 1.7 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 2.8 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.7 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation