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PRJEB1986: zebrafish developmental stages transcriptome

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Results for bcl11aa

Z-value: 0.67

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Transcription factors associated with bcl11aa

Gene Symbol Gene ID Gene Info
bcl11aa
ENSDARG00000061352 BAF chromatin remodeling complex subunit BCL11A a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
bcl11aadr11_v1_chr13_+_25846528_258465280.522.3e-02Click!

Activity profile of bcl11aa motif

Sorted Z-values of bcl11aa motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_18974064 2.41 ENSDART00000079248
slc6a19b
solute carrier family 6 (neutral amino acid transporter), member 19b
chr22_-_31517300 1.49 ENSDART00000164799
slc6a6b
solute carrier family 6 (neurotransmitter transporter), member 6b
chr16_-_13612650 1.43 ENSDART00000080372
dbpb
D site albumin promoter binding protein b
chr9_-_44939104 1.38 ENSDART00000192903
vil1
villin 1
chr5_-_18046053 1.37 ENSDART00000144898
rnf215
ring finger protein 215
chr15_+_39977461 1.33 ENSDART00000063786
cab39
calcium binding protein 39
chr18_+_8805575 1.20 ENSDART00000137098
impdh1a
IMP (inosine 5'-monophosphate) dehydrogenase 1a
chr5_-_38384289 1.08 ENSDART00000135260
mink1
misshapen-like kinase 1
chr2_+_22694382 1.04 ENSDART00000139196
kif1ab
kinesin family member 1Ab
chr7_+_49865049 0.99 ENSDART00000164165
slc1a2a
solute carrier family 1 (glial high affinity glutamate transporter), member 2a
chr10_+_38526496 0.96 ENSDART00000144329
acer3
alkaline ceramidase 3
chr21_-_21096437 0.93 ENSDART00000186552
ank1b
ankyrin 1, erythrocytic b
chr23_+_40908583 0.89 ENSDART00000180933
LO017845.1

chr17_+_15882533 0.86 ENSDART00000164124
gabrr2a
gamma-aminobutyric acid (GABA) A receptor, rho 2a
chr24_+_37722048 0.85 ENSDART00000191918
rab11fip3
RAB11 family interacting protein 3 (class II)
chr5_-_43682930 0.83 ENSDART00000075017
si:dkey-40c11.1
si:dkey-40c11.1
chr8_-_43997538 0.83 ENSDART00000186449
rimbp2
RIMS binding protein 2
chr25_+_4541211 0.82 ENSDART00000129978
pnpla2
patatin-like phospholipase domain containing 2
chr4_+_20255160 0.82 ENSDART00000188658
lrtm2a
leucine-rich repeats and transmembrane domains 2a
chr8_-_43456025 0.81 ENSDART00000001092
ENSDART00000140618
ncor2
nuclear receptor corepressor 2
chr24_+_26379441 0.80 ENSDART00000137786
si:ch211-230g15.5
si:ch211-230g15.5
chr13_-_23270576 0.78 ENSDART00000132828
si:dkey-103j14.5
si:dkey-103j14.5
chr5_-_18446483 0.78 ENSDART00000180027
si:dkey-215k6.1
si:dkey-215k6.1
chr11_+_38280454 0.78 ENSDART00000171496
CDK18
si:dkey-166c18.1
chr19_-_22488952 0.77 ENSDART00000179856
ENSDART00000141503
pleca
plectin a
chr13_+_31177934 0.73 ENSDART00000144568
ptpn20
protein tyrosine phosphatase, non-receptor type 20
chr15_-_26636826 0.73 ENSDART00000087632
slc47a4
solute carrier family 47 (multidrug and toxin extrusion), member 4
chr14_+_29975268 0.73 ENSDART00000172985
cyp4v7
cytochrome P450, family 4, subfamily V, polypeptide 7
chr11_+_30058139 0.70 ENSDART00000112254
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr3_-_45298487 0.69 ENSDART00000102245
pdpk1a
3-phosphoinositide dependent protein kinase 1a
chr7_-_2163361 0.69 ENSDART00000173654
si:cabz01007812.1
si:cabz01007812.1
chr3_-_37476278 0.68 ENSDART00000083442
si:ch211-278a6.1
si:ch211-278a6.1
chr6_+_10534752 0.67 ENSDART00000090874
kcnh7
potassium channel, voltage gated eag related subfamily H, member 7
chr21_+_27283054 0.67 ENSDART00000139058
si:dkey-175m17.7
si:dkey-175m17.7
chr2_-_5505094 0.67 ENSDART00000145035
saga
S-antigen; retina and pineal gland (arrestin) a
chr9_+_17984358 0.65 ENSDART00000192399
akap11
A kinase (PRKA) anchor protein 11
chr2_+_38804223 0.61 ENSDART00000147939
carmil3
capping protein regulator and myosin 1 linker 3
chr5_+_61556172 0.61 ENSDART00000131937
orai2
ORAI calcium release-activated calcium modulator 2
chr9_+_41612642 0.61 ENSDART00000138473
spegb
SPEG complex locus b
chr21_+_5915041 0.60 ENSDART00000151370
prodha
proline dehydrogenase (oxidase) 1a
chr22_-_38819603 0.59 ENSDART00000104437
si:ch211-262h13.5
si:ch211-262h13.5
chr3_-_56512473 0.59 ENSDART00000125439
ENSDART00000181743
cyth1a
cytohesin 1a
chr3_+_22905341 0.58 ENSDART00000111435
hdac5
histone deacetylase 5
chr3_+_15773991 0.56 ENSDART00000089923
znf652
zinc finger protein 652
chr17_+_19730001 0.53 ENSDART00000155025
grem2a
gremlin 2, DAN family BMP antagonist a
chr11_-_40257225 0.52 ENSDART00000139009
TRIM62 (1 of many)
si:ch211-193i15.2
chr2_-_24369087 0.51 ENSDART00000081237
plvapa
plasmalemma vesicle associated protein a
chr22_-_20379045 0.51 ENSDART00000183511
zbtb7a
zinc finger and BTB domain containing 7a
chr10_+_29204581 0.50 ENSDART00000148503
picalma
phosphatidylinositol binding clathrin assembly protein a
chr7_+_39706004 0.50 ENSDART00000161856
ccl36.1
chemokine (C-C motif) ligand 36, duplicate 1
chr16_+_27957808 0.48 ENSDART00000133696
znf804b
zinc finger protein 804B
chr16_+_8716800 0.47 ENSDART00000124693
ENSDART00000181961
cabz01093075.1
cabz01093075.1
chr21_+_37357578 0.46 ENSDART00000143621
nsd1b
nuclear receptor binding SET domain protein 1b
chr14_-_33177935 0.46 ENSDART00000180583
ENSDART00000078856
dlg3
discs, large homolog 3 (Drosophila)
chr17_+_27134806 0.46 ENSDART00000151901
rps6ka1
ribosomal protein S6 kinase a, polypeptide 1
chr17_-_44776224 0.44 ENSDART00000156195
zdhhc22
zinc finger, DHHC-type containing 22
chr8_+_47188154 0.44 ENSDART00000137319
si:dkeyp-100a1.6
si:dkeyp-100a1.6
chr7_+_50109239 0.44 ENSDART00000021605
LRRC4C (1 of many)
si:dkey-6l15.1
chr20_+_46216431 0.40 ENSDART00000185384
stx7l
syntaxin 7-like
chr15_-_36352983 0.40 ENSDART00000059786
si:dkey-23k10.5
si:dkey-23k10.5
chr3_-_56924654 0.40 ENSDART00000157038
hid1a
HID1 domain containing a
chr14_-_45702721 0.38 ENSDART00000165727
si:dkey-226n24.1
si:dkey-226n24.1
chr4_+_34126849 0.38 ENSDART00000162442
si:ch211-223g7.6
si:ch211-223g7.6
chr8_+_36803415 0.38 ENSDART00000111680
iqsec2b
IQ motif and Sec7 domain 2b
chr11_+_23957440 0.37 ENSDART00000190721
cntn2
contactin 2
chr17_-_45254585 0.37 ENSDART00000185507
ENSDART00000172080
ttbk2a
tau tubulin kinase 2a
chr3_-_31833266 0.37 ENSDART00000084932
ENSDART00000183617
map3k3
mitogen-activated protein kinase kinase kinase 3
chr15_-_38154616 0.37 ENSDART00000099392
irgq2
immunity-related GTPase family, q2
chr18_+_40354998 0.36 ENSDART00000098791
ENSDART00000049171
sema6dl
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr25_-_27564590 0.36 ENSDART00000073508
hyal4
hyaluronoglucosaminidase 4
chr6_-_21830405 0.36 ENSDART00000151803
ENSDART00000113497
setd5
SET domain containing 5
chr6_+_45918981 0.35 ENSDART00000149642
h6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr2_-_14387335 0.35 ENSDART00000189332
ENSDART00000164786
ENSDART00000188572
sgip1b
SH3-domain GRB2-like (endophilin) interacting protein 1b
chr17_+_8899016 0.34 ENSDART00000150214
psmc1a
proteasome 26S subunit, ATPase 1a
chr24_-_31306724 0.34 ENSDART00000165399
acp5b
acid phosphatase 5b, tartrate resistant
chr9_-_22352280 0.33 ENSDART00000115384
ENSDART00000060361
crygm5
crystallin, gamma M5
chr2_+_3516913 0.32 ENSDART00000109346
CU693445.1

chr10_+_19039507 0.31 ENSDART00000193538
ENSDART00000111952
ENSDART00000180093
igsf9a
immunoglobulin superfamily, member 9a
chr8_+_10835456 0.30 ENSDART00000151388
mapk13
mitogen-activated protein kinase 13
chr10_-_15128771 0.30 ENSDART00000101261
spp1
secreted phosphoprotein 1
chr13_-_47403154 0.29 ENSDART00000114318
bcl2l11
BCL2 like 11
chr24_-_18876877 0.28 ENSDART00000186269
arfgef1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr4_+_3980247 0.28 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr9_-_30160897 0.28 ENSDART00000143986
abi3bpa
ABI family, member 3 (NESH) binding protein a
chr11_+_4026229 0.28 ENSDART00000041417
camk1b
calcium/calmodulin-dependent protein kinase Ib
chr24_+_10302955 0.27 ENSDART00000112455
ENSDART00000066794
ENSDART00000149432
otulina
otulina
OTU deubiquitinase with linear linkage specificity a
OTU deubiquitinase with linear linkage specificity a
chr19_+_7552699 0.26 ENSDART00000180788
ENSDART00000115058
pbxip1a
pre-B-cell leukemia homeobox interacting protein 1a
chr24_-_36680261 0.26 ENSDART00000059507
ccr10
chemokine (C-C motif) receptor 10
chr1_+_23406403 0.26 ENSDART00000189921
chrna9
cholinergic receptor, nicotinic, alpha 9
chr4_+_17336557 0.25 ENSDART00000111650
pmch
pro-melanin-concentrating hormone
chr6_-_7438584 0.25 ENSDART00000053776
fkbp11
FK506 binding protein 11
chr2_+_24786765 0.24 ENSDART00000141030
pde4ca
phosphodiesterase 4C, cAMP-specific a
chr16_+_38820660 0.24 ENSDART00000182538
ENSDART00000189879
trhra
thyrotropin-releasing hormone receptor a
chr18_+_40525408 0.23 ENSDART00000132833
vwa7
von Willebrand factor A domain containing 7
chr3_-_25369557 0.23 ENSDART00000055491
smurf2
SMAD specific E3 ubiquitin protein ligase 2
chr9_+_33267211 0.21 ENSDART00000025635
usp9
ubiquitin specific peptidase 9
chr6_-_19023468 0.21 ENSDART00000184729
sept9b
septin 9b
chr9_+_51655636 0.21 ENSDART00000169908
RBMS1 (1 of many)
RNA binding motif single stranded interacting protein 1
chr21_-_28439596 0.20 ENSDART00000089980
ENSDART00000132844
rasgrp2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_-_12800945 0.20 ENSDART00000191178
txlng
taxilin gamma
chr1_+_39597809 0.20 ENSDART00000122700
tenm3
teneurin transmembrane protein 3
chr5_+_54422941 0.20 ENSDART00000175157
traf2b
Tnf receptor-associated factor 2b
chr16_+_26439939 0.19 ENSDART00000143073
trim35-28
tripartite motif containing 35-28
chr11_-_12801157 0.19 ENSDART00000103449
txlng
taxilin gamma
chr19_-_8798178 0.19 ENSDART00000188232
cers2a
ceramide synthase 2a
chr3_+_51660158 0.19 ENSDART00000155512
ENSDART00000171764
chmp6a
charged multivesicular body protein 6a
chr16_-_16619854 0.17 ENSDART00000150512
ENSDART00000191306
ENSDART00000181773
ENSDART00000183231
cyp21a2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr2_+_21855291 0.17 ENSDART00000186204
ca8
carbonic anhydrase VIII
chr16_+_10963602 0.15 ENSDART00000141032
pou2f2a
POU class 2 homeobox 2a
chr7_+_46368520 0.15 ENSDART00000192821
znf536
zinc finger protein 536
chr25_-_22889519 0.15 ENSDART00000128250
mob2a
MOB kinase activator 2a
chr25_-_27564205 0.14 ENSDART00000157319
hyal4
hyaluronoglucosaminidase 4
chr20_+_38285671 0.14 ENSDART00000061432
ccl38a.4
chemokine (C-C motif) ligand 38, duplicate 4
chr19_-_22478888 0.14 ENSDART00000090679
pleca
plectin a
chr23_-_4975452 0.13 ENSDART00000105241
ENSDART00000169978
ngfa
nerve growth factor a (beta polypeptide)
chr2_-_36925561 0.13 ENSDART00000187690
map1sb
microtubule-associated protein 1Sb
chr11_-_29685853 0.13 ENSDART00000128468
nr0b1
nuclear receptor subfamily 0, group B, member 1
chr17_+_5351922 0.13 ENSDART00000105394
runx2a
runt-related transcription factor 2a
chr17_+_5426087 0.13 ENSDART00000131430
ENSDART00000188636
runx2a
runt-related transcription factor 2a
chr20_+_40150612 0.13 ENSDART00000143680
ENSDART00000109681
ENSDART00000101041
ENSDART00000121818
trdn
triadin
chr25_+_18953756 0.12 ENSDART00000154291
tdg.2
thymine DNA glycosylase, tandem duplicate 2
chr15_+_29662401 0.12 ENSDART00000135540
nrip1a
nuclear receptor interacting protein 1a
chr7_-_29571615 0.12 ENSDART00000019140
rorab
RAR-related orphan receptor A, paralog b
chr16_+_19014886 0.11 ENSDART00000079298
si:ch211-254p10.2
si:ch211-254p10.2
chr11_-_30601401 0.11 ENSDART00000172244
ENSDART00000046800
slc8a1a
solute carrier family 8 (sodium/calcium exchanger), member 1a
chr25_+_15997957 0.11 ENSDART00000140047
ppfibp2b
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr20_-_14054083 0.11 ENSDART00000009549
rhag
Rh associated glycoprotein
chr24_+_39277043 0.11 ENSDART00000165458
MPRIP
si:ch73-103b11.2
chr6_+_13606410 0.11 ENSDART00000104716
asic4b
acid-sensing (proton-gated) ion channel family member 4b
chr16_-_39900665 0.10 ENSDART00000136719
rbms3
RNA binding motif, single stranded interacting protein
chr6_-_16394528 0.10 ENSDART00000089445
agap1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr16_+_8695595 0.10 ENSDART00000173249
si:cabz01093077.1
si:cabz01093077.1
chr24_+_13635387 0.10 ENSDART00000105997
trpa1b
transient receptor potential cation channel, subfamily A, member 1b
chr22_-_10470663 0.09 ENSDART00000143352
omd
osteomodulin
chr8_+_45294767 0.09 ENSDART00000191527
ubap2b
ubiquitin associated protein 2b
chr20_+_52554352 0.09 ENSDART00000153217
ENSDART00000145230
eef1db
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr5_-_60885935 0.09 ENSDART00000128350
rad51d
RAD51 paralog D
chr16_+_11724230 0.09 ENSDART00000060266
ceacam1
carcinoembryonic antigen-related cell adhesion molecule 1
chr14_+_24845941 0.08 ENSDART00000187513
arhgef37
Rho guanine nucleotide exchange factor (GEF) 37
chr21_-_11632403 0.08 ENSDART00000171708
ENSDART00000138619
ENSDART00000136308
ENSDART00000144770
cast
calpastatin
chr19_+_3849378 0.08 ENSDART00000166218
ENSDART00000159228
oscp1a
organic solute carrier partner 1a
chr25_+_31929325 0.07 ENSDART00000181095
apba2a
amyloid beta (A4) precursor protein-binding, family A, member 2a
chr14_-_33095917 0.07 ENSDART00000074720
dlg3
discs, large homolog 3 (Drosophila)
chr7_-_7810348 0.07 ENSDART00000171984
cxcl19
chemokine (C-X-C motif) ligand 19
chr7_-_7984015 0.07 ENSDART00000163203
si:cabz01030277.1
si:cabz01030277.1
chr5_-_31926906 0.06 ENSDART00000187340
ssh1b
slingshot protein phosphatase 1b
chr25_-_35996141 0.06 ENSDART00000149074
sall1b
spalt-like transcription factor 1b
chr6_+_34868156 0.05 ENSDART00000149364
il23r
interleukin 23 receptor
chr17_-_26868169 0.05 ENSDART00000157204
si:dkey-221l4.10
si:dkey-221l4.10
chr22_-_10397600 0.05 ENSDART00000181964
ENSDART00000142886
nisch
nischarin
chr5_+_24156170 0.05 ENSDART00000136570
slc25a15b
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15b
chr24_-_18877118 0.05 ENSDART00000092783
arfgef1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr11_+_30057762 0.04 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr1_+_33217911 0.03 ENSDART00000136761
prkx
protein kinase, X-linked
chr8_-_25690966 0.03 ENSDART00000033701
sema3ga
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ga
chr6_+_38626926 0.03 ENSDART00000190339
atp10a
ATPase phospholipid transporting 10A
chr16_-_29527412 0.03 ENSDART00000175376
onecutl
one cut domain, family member, like
chr20_-_20821783 0.02 ENSDART00000152577
ENSDART00000027603
ENSDART00000145601
ckbb
creatine kinase, brain b
chr14_+_45970033 0.02 ENSDART00000047716
fermt3b
fermitin family member 3b
chr2_-_6482240 0.01 ENSDART00000132623
rgs13
regulator of G protein signaling 13
chr16_+_26439518 0.01 ENSDART00000041787
trim35-28
tripartite motif containing 35-28
chr7_+_59677273 0.00 ENSDART00000039535
ENSDART00000132044
trmt44
tRNA methyltransferase 44 homolog

Network of associatons between targets according to the STRING database.

First level regulatory network of bcl11aa

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:2000392 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.2 0.7 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 0.8 GO:0010898 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.2 0.8 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1 0.7 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.4 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.1 0.6 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 1.2 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 0.8 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.1 0.5 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 1.0 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.1 1.4 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.1 0.7 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.2 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.7 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.3 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 1.5 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.3 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.6 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.8 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.3 GO:0045453 bone resorption(GO:0045453)
0.0 1.3 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0042148 strand invasion(GO:0042148)
0.0 0.1 GO:0008584 male gonad development(GO:0008584)
0.0 1.1 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.9 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.2 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 2.6 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.4 GO:0008345 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 0.6 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.6 GO:0002548 monocyte chemotaxis(GO:0002548)
0.0 0.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.5 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0044316 cone cell pedicle(GO:0044316)
0.3 1.4 GO:0032433 filopodium tip(GO:0032433)
0.1 0.8 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 1.4 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.9 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.5 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.3 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.6 GO:0031430 M band(GO:0031430)
0.0 0.9 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0043218 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.0 1.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 1.0 GO:0017040 ceramidase activity(GO:0017040)
0.2 0.8 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.2 0.6 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.9 GO:0030507 spectrin binding(GO:0030507)
0.1 0.9 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.7 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.8 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.7 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 1.5 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.6 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.0 0.5 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.9 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.5 GO:0030546 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 1.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 1.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 3.4 GO:0015293 symporter activity(GO:0015293)
0.0 0.8 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 0.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.8 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions