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PRJEB1986: zebrafish developmental stages transcriptome

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Results for crx+otx1

Z-value: 1.17

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Transcription factors associated with crx+otx1

Gene Symbol Gene ID Gene Info
crx
ENSDARG00000011989 cone-rod homeobox
otx1
ENSDARG00000094992 orthodenticle homeobox 1
crx
ENSDARG00000113850 cone-rod homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
otx1dr11_v1_chr17_+_24320861_24320861-0.716.0e-04Click!
crxdr11_v1_chr5_+_36932718_369327180.077.7e-01Click!

Activity profile of crx+otx1 motif

Sorted Z-values of crx+otx1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_13366353 4.21 ENSDART00000151630
si:ch73-62l21.1
si:ch73-62l21.1
chr4_+_68562464 3.41 ENSDART00000192954
BX548011.4

chr1_+_5576151 3.17 ENSDART00000109756
cpo
carboxypeptidase O
chr4_-_16853464 3.12 ENSDART00000125743
ENSDART00000164570
slc25a3a
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3a
chr6_+_54538948 3.10 ENSDART00000149270
tulp1b
tubby like protein 1b
chr1_-_58766424 2.56 ENSDART00000191010
CABZ01096573.1

chr17_+_30448452 2.54 ENSDART00000153939
lpin1
lipin 1
chr19_-_5207361 2.53 ENSDART00000174611
stx1b
syntaxin 1B
chr10_+_17026870 2.51 ENSDART00000184529
ENSDART00000157480
CR855996.2

chr6_-_16406210 2.46 ENSDART00000012023
faimb
Fas apoptotic inhibitory molecule b
chr10_-_35108683 2.42 ENSDART00000049633
zgc:110006
zgc:110006
chr25_-_19090479 2.27 ENSDART00000027465
ENSDART00000177670
cacna2d4b
calcium channel, voltage-dependent, alpha 2/delta subunit 4b
chr7_+_19903924 2.26 ENSDART00000159112
si:ch211-285j22.3
si:ch211-285j22.3
chr8_-_46572298 2.20 ENSDART00000030470
sult1st3
sulfotransferase family 1, cytosolic sulfotransferase 3
chr11_-_37693019 2.20 ENSDART00000102898
zgc:158258
zgc:158258
chr3_+_29980603 2.08 ENSDART00000151509
kcna7
potassium voltage-gated channel, shaker-related subfamily, member 7
chr17_-_51202339 2.01 ENSDART00000167117
si:ch1073-469d17.2
si:ch1073-469d17.2
chr7_-_39378903 2.00 ENSDART00000173659
slc8b1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr3_+_62000822 1.95 ENSDART00000106680
rai1
retinoic acid induced 1
chr24_+_35975398 1.92 ENSDART00000173058
obscnb
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b
chr18_+_10784730 1.90 ENSDART00000028938
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr24_-_38079261 1.88 ENSDART00000105662
crp1
C-reactive protein 1
chr4_+_72797711 1.87 ENSDART00000190934
ENSDART00000163236
MYRFL
myelin regulatory factor-like
chr17_+_50701748 1.87 ENSDART00000191938
ENSDART00000183220
ENSDART00000049464
fermt2
fermitin family member 2
chr18_+_50089000 1.86 ENSDART00000058936
scamp5b
secretory carrier membrane protein 5b
chr4_+_7841627 1.85 ENSDART00000037997
ucmaa
upper zone of growth plate and cartilage matrix associated a
chr22_+_17203752 1.85 ENSDART00000143376
rab3b
RAB3B, member RAS oncogene family
chr5_-_69180587 1.83 ENSDART00000156681
ENSDART00000160753
zgc:171967
zgc:171967
chr16_+_4055331 1.83 ENSDART00000128978
CR391998.1

chr18_-_8579907 1.79 ENSDART00000147284
FRMD4A
si:ch211-220f12.1
chr21_-_28340977 1.79 ENSDART00000141629
nrxn2a
neurexin 2a
chr1_+_23162124 1.78 ENSDART00000188428
si:dkey-92j12.5
si:dkey-92j12.5
chr7_+_19904136 1.77 ENSDART00000173452
si:ch211-285j22.3
si:ch211-285j22.3
chr20_+_46560258 1.71 ENSDART00000122115
si:ch211-153j24.3
si:ch211-153j24.3
chr12_+_2660733 1.68 ENSDART00000152235
irbpl
interphotoreceptor retinoid-binding protein like
chr23_+_7710721 1.68 ENSDART00000186852
ENSDART00000161193
kif3b
kinesin family member 3B
chr3_+_15296824 1.65 ENSDART00000043801
cabp5b
calcium binding protein 5b
chr23_+_5465806 1.61 ENSDART00000149434
ENSDART00000148506
tulp1a
tubby like protein 1a
chr24_-_31140356 1.61 ENSDART00000167837
tmem56a
transmembrane protein 56a
chr1_-_58009216 1.60 ENSDART00000143829
nxnl1
nucleoredoxin like 1
chr9_-_55744713 1.58 ENSDART00000157570
asmt
acetylserotonin O-methyltransferase
chr11_+_6295370 1.55 ENSDART00000139882
ranbp3a
RAN binding protein 3a
chr19_+_14921000 1.47 ENSDART00000144052
oprd1a
opioid receptor, delta 1a
chr23_+_39963599 1.45 ENSDART00000166539
fyco1a
FYVE and coiled-coil domain containing 1a
chr18_+_3634652 1.44 ENSDART00000159913
lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr6_-_28980756 1.44 ENSDART00000014661
glmnb
glomulin, FKBP associated protein b
chr1_-_24349759 1.42 ENSDART00000142740
ENSDART00000177989
lrba
LPS-responsive vesicle trafficking, beach and anchor containing
chr12_-_35883814 1.40 ENSDART00000177986
ENSDART00000129888
cep131
centrosomal protein 131
chr19_+_7152966 1.40 ENSDART00000080348
brd2a
bromodomain containing 2a
chr2_-_51757328 1.40 ENSDART00000189286
si:ch211-9d9.1
si:ch211-9d9.1
chr7_+_67486807 1.37 ENSDART00000159989
cpne7
copine VII
chr18_-_8030073 1.35 ENSDART00000151490
shank3a
SH3 and multiple ankyrin repeat domains 3a
chr3_+_22327738 1.35 ENSDART00000055675
gh1
growth hormone 1
chr8_+_2656231 1.34 ENSDART00000160833
fam102aa
family with sequence similarity 102, member Aa
chr25_-_204019 1.30 ENSDART00000188440
ENSDART00000191735
FP236318.2

chr11_-_3366782 1.29 ENSDART00000127982
suox
sulfite oxidase
chr20_+_2134816 1.28 ENSDART00000039249
l3mbtl3
l(3)mbt-like 3 (Drosophila)
chr16_+_46497149 1.27 ENSDART00000135151
ENSDART00000058324
rpz4
rapunzel 4
chr17_-_29194219 1.27 ENSDART00000157340
sptbn5
spectrin, beta, non-erythrocytic 5
chr16_+_43219363 1.25 ENSDART00000183610
adam22
ADAM metallopeptidase domain 22
chr5_-_69180227 1.24 ENSDART00000154816
zgc:171967
zgc:171967
chr13_-_40499296 1.24 ENSDART00000158338
CNNM1
Danio rerio cyclin and CBS domain divalent metal cation transport mediator 1 (cnnm1), mRNA.
chr1_-_43712120 1.22 ENSDART00000074600
SLC9B2
si:dkey-162b23.4
chr2_+_20430366 1.22 ENSDART00000155108
si:ch211-153l6.6
si:ch211-153l6.6
chr3_-_3366590 1.22 ENSDART00000109428
ENSDART00000175329
si:dkey-46g23.1
si:dkey-46g23.1
chr2_-_26499842 1.21 ENSDART00000186929
BX569796.1

chr10_+_4875262 1.21 ENSDART00000165942
palm2
paralemmin 2
chr11_+_29770966 1.19 ENSDART00000088624
ENSDART00000124471
rpgrb
retinitis pigmentosa GTPase regulator b
chr14_+_11909966 1.19 ENSDART00000171829
frmpd3
FERM and PDZ domain containing 3
chr21_-_39058490 1.15 ENSDART00000114885
aldh3a2b
aldehyde dehydrogenase 3 family, member A2b
chr17_-_7371564 1.15 ENSDART00000060336
rab32b
RAB32b, member RAS oncogene family
chr2_+_49417900 1.13 ENSDART00000122742
ENSDART00000160783
rorcb
RAR-related orphan receptor C b
chr20_+_13969414 1.07 ENSDART00000049864
rd3
retinal degeneration 3
chr21_+_31838386 1.06 ENSDART00000135591
si:ch211-12m10.1
si:ch211-12m10.1
chr9_-_1459985 1.05 ENSDART00000124777
osbpl6
oxysterol binding protein-like 6
chr10_+_40235959 1.05 ENSDART00000145862
gramd1ba
GRAM domain containing 1Ba
chr9_+_10014817 1.04 ENSDART00000132065
nxph2a
neurexophilin 2a
chr23_+_1181248 1.02 ENSDART00000170942
utrn
utrophin
chr24_+_9475809 1.02 ENSDART00000132688
si:ch211-285f17.1
si:ch211-285f17.1
chr13_-_36050303 1.02 ENSDART00000134955
ENSDART00000139087
lgmn
legumain
chr12_+_23850661 1.01 ENSDART00000152921
svila
supervillin a
chr22_+_5176693 1.00 ENSDART00000160927
cers1
ceramide synthase 1
chr22_+_5176255 0.98 ENSDART00000092647
cers1
ceramide synthase 1
chr11_-_15090564 0.95 ENSDART00000162079
slc1a8a
solute carrier family 1 (glutamate transporter), member 8a
chr19_+_48176745 0.95 ENSDART00000164963
prdm1b
PR domain containing 1b, with ZNF domain
chr17_-_31058900 0.95 ENSDART00000134998
ENSDART00000104307
ENSDART00000172721
eml1
echinoderm microtubule associated protein like 1
chr8_-_19649617 0.90 ENSDART00000189033
fam78bb
family with sequence similarity 78, member B b
chr9_+_10014514 0.90 ENSDART00000185590
nxph2a
neurexophilin 2a
chr3_-_13068189 0.88 ENSDART00000167180
prkar1b
protein kinase, cAMP-dependent, regulatory, type I, beta
chr8_-_51806584 0.85 ENSDART00000146976
si:ch73-313l22.2
si:ch73-313l22.2
chr9_+_17982737 0.82 ENSDART00000192569
akap11
A kinase (PRKA) anchor protein 11
chr21_-_40562705 0.80 ENSDART00000158289
ENSDART00000171997
taok1b
TAO kinase 1b
chr14_-_6402769 0.79 ENSDART00000121552
slc44a1b
solute carrier family 44 (choline transporter), member 1b
chr5_+_9434288 0.78 ENSDART00000162089
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr13_+_733027 0.78 ENSDART00000149547
nrxn1b
neurexin 1b
chr8_+_28724692 0.78 ENSDART00000140115
ccser1
coiled-coil serine-rich protein 1
chr3_-_30218504 0.77 ENSDART00000103487
zgc:195001
zgc:195001
chr23_+_45512825 0.77 ENSDART00000064846
prelid1b
PRELI domain containing 1b
chr13_+_2442841 0.75 ENSDART00000114456
ENSDART00000137124
ENSDART00000193737
ENSDART00000189722
ENSDART00000187485
arfgef3
ARFGEF family member 3
chr14_-_31694274 0.75 ENSDART00000173353
map7d3
MAP7 domain containing 3
chr2_+_30721070 0.74 ENSDART00000099052
si:dkey-94e7.2
si:dkey-94e7.2
chr14_+_2487672 0.72 ENSDART00000170629
ENSDART00000123063
fgf18a
fibroblast growth factor 18a
chr7_-_38340674 0.72 ENSDART00000075782
slc7a10a
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10a
chr10_-_42898220 0.72 ENSDART00000099270
CU326366.2

chr15_+_46605482 0.71 ENSDART00000184449
CABZ01044048.1

chr22_+_30047245 0.71 ENSDART00000142857
ENSDART00000141247
ENSDART00000140015
ENSDART00000040538
add3a
adducin 3 (gamma) a
chr21_-_2209012 0.69 ENSDART00000158345
zgc:162971
zgc:162971
chr4_+_33537372 0.69 ENSDART00000181450
si:dkey-84h14.2
si:dkey-84h14.2
chr9_-_5318873 0.69 ENSDART00000129308
ACVR1C
activin A receptor type 1C
chr9_-_46276626 0.69 ENSDART00000165238
hdac4
histone deacetylase 4
chr12_+_49100365 0.68 ENSDART00000171905
CABZ01075125.1

chr25_-_10629940 0.67 ENSDART00000154483
ENSDART00000155231
ppp6r3
protein phosphatase 6, regulatory subunit 3
chr6_-_10168822 0.66 ENSDART00000151016
b3galt1a
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1a
chr9_-_135774 0.66 ENSDART00000160435
FQ377903.1

chr4_+_12111154 0.66 ENSDART00000036779
tmem178b
transmembrane protein 178B
chr4_-_908821 0.66 ENSDART00000168266
mrap2b
melanocortin 2 receptor accessory protein 2b
chr25_-_4733008 0.65 ENSDART00000191884
drd4a
dopamine receptor D4a
chr21_-_20765338 0.64 ENSDART00000135940
ghrb
growth hormone receptor b
chr9_-_2945008 0.63 ENSDART00000183452
zak
sterile alpha motif and leucine zipper containing kinase AZK
chr1_+_55264712 0.62 ENSDART00000193162
BX284640.1

chr18_+_19006063 0.60 ENSDART00000135729
slc24a1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr9_+_1313418 0.59 ENSDART00000191361
casp8l2
caspase 8, apoptosis-related cysteine peptidase, like 2
chr19_+_34169055 0.58 ENSDART00000135592
ENSDART00000186043
poc1bl
POC1 centriolar protein homolog B (Chlamydomonas), like
chr25_+_35891342 0.58 ENSDART00000147093
lsm14aa
LSM14A mRNA processing body assembly factor a
chr5_-_40910749 0.58 ENSDART00000083467
ENSDART00000133183
parp8
poly (ADP-ribose) polymerase family, member 8
chr2_-_37537887 0.57 ENSDART00000143496
ENSDART00000025841
arhgef18a
rho/rac guanine nucleotide exchange factor (GEF) 18a
chr13_+_12528043 0.56 ENSDART00000057761
rrh
retinal pigment epithelium-derived rhodopsin homolog
chr23_-_42810664 0.56 ENSDART00000102328
pfkfb2a
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr19_-_35340027 0.56 ENSDART00000146394
macf1a
microtubule-actin crosslinking factor 1a
chr15_-_26931541 0.55 ENSDART00000027563
ccdc9
coiled-coil domain containing 9
chr2_-_32551178 0.55 ENSDART00000145603
smarcd3a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3a
chr10_+_39476600 0.54 ENSDART00000135756
kirrel3a
kirre like nephrin family adhesion molecule 3a
chr13_+_1015749 0.53 ENSDART00000190982
prokr1b
prokineticin receptor 1b
chr13_-_8815530 0.53 ENSDART00000122498
si:ch73-105b23.6
si:ch73-105b23.6
chr4_+_28442223 0.53 ENSDART00000150879
znf1067
zinc finger protein 1067
chr17_+_10593398 0.52 ENSDART00000168897
ENSDART00000193989
ENSDART00000191664
ENSDART00000167188
mapkbp1
mitogen-activated protein kinase binding protein 1
chr21_+_45496442 0.51 ENSDART00000164880
si:dkey-223p19.1
si:dkey-223p19.1
chr21_+_36581384 0.51 ENSDART00000183924
BX936439.1

chr3_+_23063718 0.50 ENSDART00000140225
ENSDART00000184431
b4galnt2.1
beta-1,4-N-acetyl-galactosaminyl transferase 2, tandem duplicate 1
chr12_-_33659328 0.49 ENSDART00000153457
tmem94
transmembrane protein 94
chr7_+_22330466 0.49 ENSDART00000187347
ENSDART00000174483
fgf11a
fibroblast growth factor 11a
chr10_+_39476432 0.48 ENSDART00000190375
ENSDART00000183954
kirrel3a
kirre like nephrin family adhesion molecule 3a
chr10_-_40968095 0.47 ENSDART00000184104
npffr1l1
neuropeptide FF receptor 1 like 1
chr18_-_6975175 0.47 ENSDART00000134194
si:dkey-266m15.6
si:dkey-266m15.6
chr16_+_54592907 0.46 ENSDART00000172113
dennd4b
DENN/MADD domain containing 4B
chr8_+_4838114 0.45 ENSDART00000146667
es1
es1 protein
chr7_+_20030888 0.45 ENSDART00000192808
slc16a13
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr20_-_30920356 0.44 ENSDART00000022951
kif25
kinesin family member 25
chr23_+_16935494 0.43 ENSDART00000143120
si:dkey-147f3.4
si:dkey-147f3.4
chr24_-_21689146 0.43 ENSDART00000105917
urad
ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
chr14_+_52413846 0.43 ENSDART00000160952
noa1
nitric oxide associated 1
chr7_+_39011852 0.41 ENSDART00000093009
dgkza
diacylglycerol kinase, zeta a
chr10_-_322769 0.40 ENSDART00000165244
akt2l
v-akt murine thymoma viral oncogene homolog 2, like
chr4_-_49133107 0.39 ENSDART00000150806
znf1146
zinc finger protein 1146
chr20_+_53577502 0.39 ENSDART00000126983
myh6
myosin, heavy chain 6, cardiac muscle, alpha
chr25_+_35913614 0.39 ENSDART00000022437
gpia
glucose-6-phosphate isomerase a
chr18_+_27439680 0.38 ENSDART00000014726
tp53i11b
tumor protein p53 inducible protein 11b
chr11_+_19080400 0.38 ENSDART00000044423
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr5_-_23715027 0.37 ENSDART00000139020
gbgt1l1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr9_-_394088 0.37 ENSDART00000169014
si:dkey-11f4.7
si:dkey-11f4.7
chr9_+_7030016 0.36 ENSDART00000148047
ENSDART00000148181
inpp4aa
inositol polyphosphate-4-phosphatase type I Aa
chr15_-_34468599 0.35 ENSDART00000192984
meox2a
mesenchyme homeobox 2a
chr11_-_15090118 0.35 ENSDART00000171118
slc1a8a
solute carrier family 1 (glutamate transporter), member 8a
chr20_-_35012093 0.35 ENSDART00000062761
cnstb
consortin, connexin sorting protein b
chr14_+_30340251 0.34 ENSDART00000148448
mtus1a
microtubule associated tumor suppressor 1a
chr15_+_25683069 0.33 ENSDART00000148190
hic1
hypermethylated in cancer 1
chr23_-_437467 0.33 ENSDART00000192106
tspan2b
tetraspanin 2b
chr10_+_6013076 0.32 ENSDART00000167613
ENSDART00000159216
hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr9_+_1365747 0.31 ENSDART00000140917
ENSDART00000036605
prkra
protein kinase, interferon-inducible double stranded RNA dependent activator
chr6_-_39218609 0.28 ENSDART00000133305
os9
osteosarcoma amplified 9, endoplasmic reticulum lectin
chr23_-_35064785 0.28 ENSDART00000172240
BX294434.1

chr20_+_54666222 0.27 ENSDART00000166592
CABZ01087948.1

chr15_+_887032 0.27 ENSDART00000156395
si:dkey-7i4.9
si:dkey-7i4.9
chr21_-_38853737 0.25 ENSDART00000184100
tlr22
toll-like receptor 22
chr4_+_50401133 0.25 ENSDART00000150644
si:dkey-156k2.7
si:dkey-156k2.7
chr5_-_27994679 0.24 ENSDART00000132740
ppp3cca
protein phosphatase 3, catalytic subunit, gamma isozyme, a
chr2_+_30721466 0.24 ENSDART00000128982
si:dkey-94e7.2
si:dkey-94e7.2
chr19_+_43884120 0.23 ENSDART00000139684
ENSDART00000142312
lypla2
lysophospholipase II
chr15_+_20355465 0.23 ENSDART00000143092
ENSDART00000062666
il15l
interleukin 15, like
chr4_-_73561848 0.22 ENSDART00000174210
CU570689.2

chr1_+_52633367 0.21 ENSDART00000134658
slc44a1a
solute carrier family 44 (choline transporter), member 1a
chr4_+_22480169 0.20 ENSDART00000146272
ENSDART00000066904
ndufb2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr7_+_39011355 0.20 ENSDART00000173855
dgkza
diacylglycerol kinase, zeta a
chr24_+_10039165 0.20 ENSDART00000144186
pou6f2
POU class 6 homeobox 2
chr7_+_13702248 0.19 ENSDART00000172811
pdcd7
programmed cell death 7
chr7_-_54320088 0.18 ENSDART00000172396
fadd
Fas (tnfrsf6)-associated via death domain
chr25_+_16731802 0.18 ENSDART00000188715
BX004976.1

chr3_-_20058417 0.17 ENSDART00000165695
ubtf
upstream binding transcription factor, RNA polymerase I
chr20_-_2134620 0.17 ENSDART00000064375
tmem244
transmembrane protein 244
chr23_-_45501177 0.15 ENSDART00000150103
col24a1
collagen type XXIV alpha 1
chr4_+_11053301 0.15 ENSDART00000140362
ccdc59
coiled-coil domain containing 59
chr13_-_29406534 0.14 ENSDART00000100877
zgc:153142
zgc:153142
chr14_-_36412473 0.12 ENSDART00000128244
ENSDART00000138376
asb5a
ankyrin repeat and SOCS box containing 5a
chr13_+_30228077 0.12 ENSDART00000100813
ENSDART00000147729
ENSDART00000133404
rps24
ribosomal protein S24
chr17_+_14886828 0.11 ENSDART00000010507
ENSDART00000131052
ptger2a
prostaglandin E receptor 2a (subtype EP2)
chr16_+_53519048 0.10 ENSDART00000124691
smpd5
sphingomyelin phosphodiesterase 5
chr10_+_8690936 0.09 ENSDART00000144218
si:dkey-27b3.4
si:dkey-27b3.4
chr18_-_24989580 0.07 ENSDART00000163449
chd2
chromodomain helicase DNA binding protein 2
chr9_-_3519253 0.06 ENSDART00000169586
dcaf17
ddb1 and cul4 associated factor 17
chr2_+_24080694 0.05 ENSDART00000024058
kcnh2a
potassium voltage-gated channel, subfamily H (eag-related), member 2a

Network of associatons between targets according to the STRING database.

First level regulatory network of crx+otx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0030186 melatonin metabolic process(GO:0030186)
0.5 2.5 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.4 1.5 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.3 1.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.3 1.3 GO:0050996 positive regulation of lipid catabolic process(GO:0050996)
0.3 1.0 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.2 0.7 GO:0042941 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.2 3.8 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.2 2.5 GO:1902042 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.2 1.7 GO:0043584 nose development(GO:0043584)
0.2 0.6 GO:0060292 long term synaptic depression(GO:0060292)
0.2 1.4 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.2 0.7 GO:0090299 regulation of neural crest formation(GO:0090299)
0.2 1.9 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.1 0.4 GO:0046415 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
0.1 2.3 GO:0046549 retinal cone cell development(GO:0046549)
0.1 1.6 GO:0006611 protein export from nucleus(GO:0006611)
0.1 3.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 2.2 GO:0006584 catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.1 1.2 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.3 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.3 GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.1 4.7 GO:0061512 protein localization to cilium(GO:0061512)
0.1 0.6 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.1 0.9 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 1.2 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 2.5 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 0.6 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.9 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.1 1.4 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 0.4 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.1 0.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.5 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.7 GO:0097009 energy homeostasis(GO:0097009)
0.1 4.9 GO:0030042 actin filament depolymerization(GO:0030042)
0.1 1.1 GO:0032438 melanosome organization(GO:0032438)
0.1 1.9 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.1 0.3 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.6 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.5 GO:0030431 sleep(GO:0030431)
0.1 0.7 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 1.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.7 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.2 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.3 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 1.9 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.4 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 1.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.3 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.8 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 2.1 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 1.4 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0034695 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.0 1.2 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.2 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 1.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.4 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 2.1 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.6 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.0 GO:0070257 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.0 1.5 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.8 GO:0007416 synapse assembly(GO:0007416)
0.0 0.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 0.6 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 1.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 3.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 2.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.9 GO:0031430 M band(GO:0031430)
0.1 1.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.6 GO:0032019 mitochondrial cloud(GO:0032019)
0.0 0.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 2.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 2.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 2.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.1 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 2.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 2.1 GO:0005871 kinesin complex(GO:0005871)
0.0 1.4 GO:0005776 autophagosome(GO:0005776)
0.0 0.9 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 1.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 2.1 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0038046 enkephalin receptor activity(GO:0038046)
0.5 1.4 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.4 1.3 GO:0005131 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.2 2.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 3.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.2 1.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 0.7 GO:0031782 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.2 0.6 GO:0004903 growth hormone receptor activity(GO:0004903)
0.2 2.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 2.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.9 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 3.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.8 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.3 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 1.3 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.7 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.3 GO:0071253 connexin binding(GO:0071253)
0.1 2.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.7 GO:0019840 retinoid binding(GO:0005501) isoprenoid binding(GO:0019840)
0.1 0.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.4 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.7 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.7 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.7 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 1.1 GO:0015248 sterol transporter activity(GO:0015248)
0.0 2.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.9 GO:0071949 FAD binding(GO:0071949)
0.0 1.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 2.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.8 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.6 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 1.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 2.1 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.9 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.5 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 2.7 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 5.5 GO:0051015 actin filament binding(GO:0051015)
0.0 2.1 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.2 GO:0002020 protease binding(GO:0002020)
0.0 0.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.4 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.6 REACTOME OPSINS Genes involved in Opsins
0.1 1.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.7 REACTOME KINESINS Genes involved in Kinesins
0.1 1.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis