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PRJEB1986: zebrafish developmental stages transcriptome

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Results for ctcf

Z-value: 2.60

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Transcription factors associated with ctcf

Gene Symbol Gene ID Gene Info
ctcf
ENSDARG00000056621 CCCTC-binding factor (zinc finger protein)
ctcf
ENSDARG00000113285 CCCTC-binding factor (zinc finger protein)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ctcfdr11_v1_chr18_+_22287084_22287188-0.361.3e-01Click!

Activity profile of ctcf motif

Sorted Z-values of ctcf motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_22965214 9.41 ENSDART00000148178
emilin3a
elastin microfibril interfacer 3a
chr3_+_14641962 8.67 ENSDART00000091070
zgc:158403
zgc:158403
chr21_-_23331619 8.65 ENSDART00000007806
zbtb16a
zinc finger and BTB domain containing 16a
chr8_-_22964486 7.48 ENSDART00000112381
emilin3a
elastin microfibril interfacer 3a
chr18_-_14677936 6.97 ENSDART00000111995
si:dkey-238o13.4
si:dkey-238o13.4
chr22_+_20135443 6.85 ENSDART00000143641
eef2a.1
eukaryotic translation elongation factor 2a, tandem duplicate 1
chr21_-_19918286 6.77 ENSDART00000180816
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr11_-_41853874 6.40 ENSDART00000002556
mrto4
MRT4 homolog, ribosome maturation factor
chr13_-_33822550 6.13 ENSDART00000143703
flrt3
fibronectin leucine rich transmembrane 3
chr10_-_40826657 6.09 ENSDART00000076304
pcna
proliferating cell nuclear antigen
chr6_+_60125033 5.94 ENSDART00000148557
ENSDART00000008224
aurka
aurora kinase A
chr22_+_5135884 5.77 ENSDART00000141276
mydgf
myeloid-derived growth factor
chr3_+_31093455 5.61 ENSDART00000153074
si:dkey-66i24.9
si:dkey-66i24.9
chr6_-_42388608 5.58 ENSDART00000049425
sec61a1l
Sec61 translocon alpha 1 subunit, like
chr7_+_34236238 5.30 ENSDART00000052474
tipin
timeless interacting protein
chr5_+_54497475 5.28 ENSDART00000158149
ENSDART00000163968
ENSDART00000160446
tmem203
transmembrane protein 203
chr19_+_20785724 5.22 ENSDART00000038942
adnp2b
ADNP homeobox 2b
chr5_-_54497319 5.03 ENSDART00000160492
alad
aminolevulinate dehydratase
chr11_-_25257595 4.78 ENSDART00000123567
snai1a
snail family zinc finger 1a
chr2_-_20666920 4.75 ENSDART00000143437
ENSDART00000114546
ENSDART00000136113
ENSDART00000179247
dusp12
dual specificity phosphatase 12
chr11_+_2198831 4.73 ENSDART00000160515
hoxc6b
homeobox C6b
chr2_-_9744081 4.69 ENSDART00000097732
dvl3a
dishevelled segment polarity protein 3a
chr6_+_45934682 4.65 ENSDART00000103489
cenps
centromere protein S
chr14_-_41468892 4.64 ENSDART00000173099
ENSDART00000003170
mid1ip1l
MID1 interacting protein 1, like
chr1_-_8651718 4.61 ENSDART00000133319
actb1
actin, beta 1
chr2_-_37896965 4.61 ENSDART00000129852
hbl1
hexose-binding lectin 1
chr1_-_22851481 4.54 ENSDART00000054386
qdprb1
quinoid dihydropteridine reductase b1
chr17_-_29224908 4.50 ENSDART00000156288
si:dkey-28g23.6
si:dkey-28g23.6
chr25_+_19733704 4.47 ENSDART00000145334
ENSDART00000138946
ENSDART00000138851
zgc:101783
zgc:101783
chr3_-_37148594 4.42 ENSDART00000140855
mlx
MLX, MAX dimerization protein
chr21_+_43702016 4.41 ENSDART00000017176
dkc1
dyskeratosis congenita 1, dyskerin
chr12_-_4220713 4.40 ENSDART00000129427
vkorc1
vitamin K epoxide reductase complex, subunit 1
chr2_+_23701613 4.25 ENSDART00000047073
oxsr1a
oxidative stress responsive 1a
chr1_+_218524 4.25 ENSDART00000109529
tmco3
transmembrane and coiled-coil domains 3
chr19_-_33274978 4.25 ENSDART00000020301
ENSDART00000114714
fam92a1
family with sequence similarity 92, member A1
chr3_+_37790351 4.18 ENSDART00000151506
si:dkey-260c8.8
si:dkey-260c8.8
chr1_+_22851261 4.17 ENSDART00000193925
gtf2e2
general transcription factor IIE, polypeptide 2, beta
chr14_+_48045193 4.03 ENSDART00000124773
ppid
peptidylprolyl isomerase D
chr19_-_1947403 4.01 ENSDART00000113951
ENSDART00000151293
ENSDART00000134074
znrf2a
zinc and ring finger 2a
chr5_-_32396929 3.99 ENSDART00000023977
fbxw2
F-box and WD repeat domain containing 2
chr6_+_47846366 3.98 ENSDART00000064842
padi2
peptidyl arginine deiminase, type II
chr24_-_13349464 3.94 ENSDART00000134482
ENSDART00000139212
terf1
telomeric repeat binding factor (NIMA-interacting) 1
chr1_+_26676758 3.90 ENSDART00000152299
si:dkey-25o16.4
si:dkey-25o16.4
chr4_+_9177997 3.88 ENSDART00000057254
ENSDART00000154614
nfyba
nuclear transcription factor Y, beta a
chr24_-_17400143 3.87 ENSDART00000134947
cul1b
cullin 1b
chr2_-_25140022 3.82 ENSDART00000134543
nceh1a
neutral cholesterol ester hydrolase 1a
chr21_-_21514176 3.74 ENSDART00000031205
nectin3b
nectin cell adhesion molecule 3b
chr9_+_48819280 3.71 ENSDART00000112555
spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr2_-_37896646 3.69 ENSDART00000075931
hbl1
hexose-binding lectin 1
chr3_-_45777226 3.68 ENSDART00000192849
h3f3b.1
H3 histone, family 3B.1
chr25_+_19734038 3.68 ENSDART00000067354
zgc:101783
zgc:101783
chr6_-_35046735 3.63 ENSDART00000143649
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr1_+_53919110 3.62 ENSDART00000020680
nup133
nucleoporin 133
chr13_-_37600600 3.60 ENSDART00000003888
snapc1b
small nuclear RNA activating complex, polypeptide 1b
chr14_+_6954579 3.60 ENSDART00000060998
nme5
NME/NM23 family member 5
chr16_-_14587332 3.59 ENSDART00000012479
dscc1
DNA replication and sister chromatid cohesion 1
chr14_-_30557637 3.58 ENSDART00000183141
pfdn6
prefoldin subunit 6
chr5_+_41496490 3.56 ENSDART00000039369
fancg
Fanconi anemia, complementation group G
chr3_+_36671585 3.55 ENSDART00000159033
nde1
nudE neurodevelopment protein 1
chr18_+_17021391 3.52 ENSDART00000100160
chtf8
CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
chr8_+_20488322 3.50 ENSDART00000036630
zgc:101100
zgc:101100
chr12_-_5418340 3.48 ENSDART00000028043
noc3l
NOC3-like DNA replication regulator
chr6_-_41028698 3.45 ENSDART00000134293
trub2
TruB pseudouridine (psi) synthase family member 2
chr12_-_3077395 3.43 ENSDART00000002867
ENSDART00000126315
rfng
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr14_-_30557127 3.42 ENSDART00000053936
pfdn6
prefoldin subunit 6
chr14_+_22129096 3.39 ENSDART00000132514
ccng1
cyclin G1
chr19_-_19871211 3.38 ENSDART00000170980
evx1
even-skipped homeobox 1
chr22_+_10646928 3.36 ENSDART00000038465
rassf1
Ras association (RalGDS/AF-6) domain family 1
chr3_+_41647637 3.28 ENSDART00000050332
gna12a
guanine nucleotide binding protein (G protein) alpha 12a
chr25_-_16755340 3.23 ENSDART00000124729
ENSDART00000110859
ribc2
RIB43A domain with coiled-coils 2
chr3_+_24050043 3.19 ENSDART00000151788
cbx1a
chromobox homolog 1a (HP1 beta homolog Drosophila)
chr12_+_31783066 3.17 ENSDART00000105584
lrrc59
leucine rich repeat containing 59
chr15_-_17406056 3.15 ENSDART00000146735
tubd1
tubulin, delta 1
chr22_-_20403194 3.15 ENSDART00000010048
map2k2a
mitogen-activated protein kinase kinase 2a
chr19_-_3886991 3.13 ENSDART00000162085
thrap3b
thyroid hormone receptor associated protein 3b
chr2_-_26596794 3.10 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691
chr19_+_20274944 3.05 ENSDART00000151237
oxnad1
oxidoreductase NAD-binding domain containing 1
chr23_+_24501918 3.04 ENSDART00000078824
szrd1
SUZ RNA binding domain containing 1
chr8_-_11324143 3.03 ENSDART00000008215
pip5k1bb
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr24_-_13349802 3.02 ENSDART00000164729
terf1
telomeric repeat binding factor (NIMA-interacting) 1
chr16_+_40340523 2.98 ENSDART00000102571
mettl6
methyltransferase like 6
chr15_+_31911989 2.97 ENSDART00000111472
brca2
breast cancer 2, early onset
chr7_-_60156409 2.96 ENSDART00000006802
cct7
chaperonin containing TCP1, subunit 7 (eta)
chr13_-_35765028 2.96 ENSDART00000157391
erlec1
endoplasmic reticulum lectin 1
chr1_-_34713710 2.92 ENSDART00000141569
ENSDART00000102111
ENSDART00000122137
tpt1
tumor protein, translationally-controlled 1
chr4_+_12931763 2.90 ENSDART00000016382
wif1
wnt inhibitory factor 1
chr21_+_25669934 2.89 ENSDART00000101203
sumf2
sulfatase modifying factor 2
chr12_-_7639120 2.88 ENSDART00000126712
ENSDART00000126219
ccdc6b
coiled-coil domain containing 6b
chr4_-_18512550 2.87 ENSDART00000045639
rint1
RAD50 interactor 1
chr16_+_28881235 2.86 ENSDART00000146525
chtopb
chromatin target of PRMT1b
chr7_+_24049776 2.81 ENSDART00000166559
efs
embryonal Fyn-associated substrate
chr9_+_29985010 2.81 ENSDART00000020743
cmss1
cms1 ribosomal small subunit homolog (yeast)
chr20_-_30931139 2.80 ENSDART00000006778
ENSDART00000146376
acat2
acetyl-CoA acetyltransferase 2
chr2_-_37883256 2.79 ENSDART00000035685
hbl4
hexose-binding lectin 4
chr21_+_25120546 2.77 ENSDART00000149507
ddx10
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr7_+_66634167 2.75 ENSDART00000027616
eif4g2a
eukaryotic translation initiation factor 4, gamma 2a
chr1_-_45577980 2.74 ENSDART00000160961
atf7ip
activating transcription factor 7 interacting protein
chr2_-_40135942 2.73 ENSDART00000176951
ENSDART00000098632
ENSDART00000148563
ENSDART00000149895
epha4a
eph receptor A4a
chr2_+_3823813 2.72 ENSDART00000103596
ENSDART00000161880
ENSDART00000185408
npc1
Niemann-Pick disease, type C1
chr14_-_17588345 2.72 ENSDART00000143486
selenot2
selenoprotein T, 2
chr11_+_27364338 2.67 ENSDART00000186759
fbln2
fibulin 2
chr22_-_2886937 2.67 ENSDART00000063533
aqp12
aquaporin 12
chr15_+_47525073 2.66 ENSDART00000067583
sidt2
SID1 transmembrane family, member 2
chr20_-_36800002 2.65 ENSDART00000015190
ptrhd1
peptidyl-tRNA hydrolase domain containing 1
chr6_+_8153813 2.64 ENSDART00000192436
nfil3-3
nuclear factor, interleukin 3 regulated, member 3
chr21_+_261490 2.57 ENSDART00000177919
jak2a
Janus kinase 2a
chr1_+_40613297 2.56 ENSDART00000040798
ENSDART00000168067
ENSDART00000130490
naa15b
N(alpha)-acetyltransferase 15, NatA auxiliary subunit b
chr1_+_22851745 2.54 ENSDART00000138235
ENSDART00000016488
gtf2e2
general transcription factor IIE, polypeptide 2, beta
chr2_+_36606019 2.54 ENSDART00000098415
ing5b
inhibitor of growth family, member 5b
chr25_+_28823952 2.53 ENSDART00000067072
nfybb
nuclear transcription factor Y, beta b
chr5_-_29514689 2.50 ENSDART00000126018
ENSDART00000125175
ehmt1a
euchromatic histone-lysine N-methyltransferase 1a
chr20_+_49895220 2.49 ENSDART00000097865
ints9
integrator complex subunit 9
chr5_-_1869982 2.48 ENSDART00000055878
rcl1
RNA terminal phosphate cyclase-like 1
chr9_+_21148318 2.48 ENSDART00000035428
hao2
hydroxyacid oxidase 2 (long chain)
chr16_+_23799622 2.48 ENSDART00000046922
rab13
RAB13, member RAS oncogene family
chr10_-_35186310 2.48 ENSDART00000127805
pom121
POM121 transmembrane nucleoporin
chr5_+_64907368 2.45 ENSDART00000122863
ptgs1
prostaglandin-endoperoxide synthase 1
chr18_+_35229115 2.42 ENSDART00000129624
ENSDART00000184596
tbrg1
transforming growth factor beta regulator 1
chr23_-_20429741 2.40 ENSDART00000104334
taf13
TATA-box binding protein associated factor 13
chr18_+_44649804 2.32 ENSDART00000059063
ehd2b
EH-domain containing 2b
chr24_-_17400472 2.32 ENSDART00000024691
cul1b
cullin 1b
chr18_+_8402129 2.28 ENSDART00000081154
ENSDART00000171974
prpf18
PRP18 pre-mRNA processing factor 18 homolog (yeast)
chr5_-_58832332 2.28 ENSDART00000161230
arhgef12b
Rho guanine nucleotide exchange factor (GEF) 12b
chr7_+_52154215 2.27 ENSDART00000098712
TMEM208
zgc:77041
chr24_+_37800102 2.25 ENSDART00000187591
telo2
TEL2, telomere maintenance 2, homolog (S. cerevisiae)
chr6_+_21993613 2.24 ENSDART00000160750
ENSDART00000083070
thumpd3
THUMP domain containing 3
chr14_+_31473866 2.23 ENSDART00000173088
ccdc160
coiled-coil domain containing 160
chr21_-_32462856 2.23 ENSDART00000147318
zgc:123105
zgc:123105
chr8_-_20858676 2.18 ENSDART00000018515
dohh
deoxyhypusine hydroxylase/monooxygenase
chr24_+_32668675 2.16 ENSDART00000156638
ENSDART00000155973
si:ch211-282b22.1
si:ch211-282b22.1
chr19_-_3906369 2.16 ENSDART00000160299
ENSDART00000169205
si:ch73-281i18.4
si:ch73-281i18.4
chr7_-_17816175 2.13 ENSDART00000091272
ENSDART00000173757
ecsit
ECSIT signalling integrator
chr9_-_12595003 2.12 ENSDART00000184900
tra2b
transformer 2 beta homolog
chr8_-_17184482 2.11 ENSDART00000025803
pola2
polymerase (DNA directed), alpha 2
chr5_+_57320113 2.10 ENSDART00000036331
atp6v1g1
ATPase H+ transporting V1 subunit G1
chr20_+_26002534 2.08 ENSDART00000147845
nrbp1
nuclear receptor binding protein 1
chr17_+_21817002 2.08 ENSDART00000136727
ikzf5
IKAROS family zinc finger 5
chr8_+_21437908 2.08 ENSDART00000142758
si:dkey-163f12.10
si:dkey-163f12.10
chr7_-_71384391 2.05 ENSDART00000112841
ccdc149a
coiled-coil domain containing 149a
chr17_-_735537 2.05 ENSDART00000166259
wars
tryptophanyl-tRNA synthetase
chr21_+_26539157 2.04 ENSDART00000021121
stx5al
syntaxin 5A, like
chr10_+_17681074 2.03 ENSDART00000057500
drg1
developmentally regulated GTP binding protein 1
chr10_+_11355841 1.97 ENSDART00000193067
ENSDART00000064215
cops4
COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
chr12_-_17492852 1.93 ENSDART00000012421
ENSDART00000138766
ENSDART00000130735
minpp1b
multiple inositol-polyphosphate phosphatase 1b
chr15_+_22435460 1.91 ENSDART00000031976
tmem136a
transmembrane protein 136a
chr19_-_3916075 1.91 ENSDART00000161799
si:ch73-281i18.7
si:ch73-281i18.7
chr9_+_22929675 1.87 ENSDART00000061299
tsn
translin
chr14_-_30932373 1.85 ENSDART00000172988
si:zfos-80g12.1
si:zfos-80g12.1
chr25_+_8921425 1.84 ENSDART00000128591
accs
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
chr21_-_21824285 1.84 ENSDART00000030984
wdr73
WD repeat domain 73
chr17_-_25303486 1.84 ENSDART00000162235
ppie
peptidylprolyl isomerase E (cyclophilin E)
chr15_-_16323750 1.83 ENSDART00000028500
nxn
nucleoredoxin
chr8_+_26007988 1.83 ENSDART00000193948
ENSDART00000058100
xpc
xeroderma pigmentosum, complementation group C
chr8_-_13364879 1.83 ENSDART00000063863
ccdc124
coiled-coil domain containing 124
chr18_-_40753583 1.81 ENSDART00000026767
akt2
v-akt murine thymoma viral oncogene homolog 2
chr12_-_31726748 1.80 ENSDART00000153174
srsf2a
serine/arginine-rich splicing factor 2a
chr16_+_11585576 1.80 ENSDART00000172967
si:dkey-11o1.6
si:dkey-11o1.6
chr7_-_34256374 1.78 ENSDART00000075176
dis3l
DIS3 like exosome 3'-5' exoribonuclease
chr20_+_9763364 1.77 ENSDART00000053834
psmc6
proteasome 26S subunit, ATPase 6
chr11_+_22623284 1.77 ENSDART00000111850
si:ch211-86h15.1
si:ch211-86h15.1
chr12_-_33582382 1.77 ENSDART00000009794
ENSDART00000136617
tdrkh
tudor and KH domain containing
chr6_-_379248 1.76 ENSDART00000172052
si:zfos-169g10.2
si:zfos-169g10.2
chr19_-_3925801 1.76 ENSDART00000129570
ENSDART00000163138
si:ch73-281i18.6
si:ch73-281i18.6
chr12_-_10567188 1.75 ENSDART00000144283
myof
myoferlin
chr8_-_51954562 1.74 ENSDART00000132527
ENSDART00000057315
cep78
centrosomal protein 78
chr22_-_3344613 1.74 ENSDART00000165600
tbxa2r
thromboxane A2 receptor
chr2_-_38282079 1.72 ENSDART00000145808
rnf212b
si:ch211-10e2.1
chr9_-_12594759 1.69 ENSDART00000021266
tra2b
transformer 2 beta homolog
chr5_+_32076109 1.68 ENSDART00000051357
ENSDART00000144510
zmat5
zinc finger, matrin-type 5
chr21_+_17024002 1.65 ENSDART00000080628
arpc3
actin related protein 2/3 complex, subunit 3
chr13_+_35528607 1.64 ENSDART00000075414
ENSDART00000112947
wdr27
WD repeat domain 27
chr18_+_3140682 1.61 ENSDART00000166382
clns1a
chloride channel, nucleotide-sensitive, 1A
chr21_+_6114709 1.61 ENSDART00000065858
fpgs
folylpolyglutamate synthase
chr19_+_18903533 1.59 ENSDART00000157523
ENSDART00000166562
slc39a7
solute carrier family 39 (zinc transporter), member 7
chr5_-_28052883 1.57 ENSDART00000188791
zgc:113436
zgc:113436
chr12_-_11294979 1.56 ENSDART00000148850
get4
golgi to ER traffic protein 4 homolog (S. cerevisiae)
chr17_+_22577472 1.56 ENSDART00000045099
yipf4
Yip1 domain family, member 4
chr2_+_57149002 1.55 ENSDART00000168497
eef2b
eukaryotic translation elongation factor 2b
chr14_+_7377552 1.55 ENSDART00000142158
ENSDART00000141471
hars
histidyl-tRNA synthetase
chr8_+_25900049 1.53 ENSDART00000124300
ENSDART00000127618
ENSDART00000024009
rhoab
ras homolog gene family, member Ab
chr9_-_14273652 1.52 ENSDART00000135458
abcb6b
ATP-binding cassette, sub-family B (MDR/TAP), member 6b
chr19_-_3896514 1.51 ENSDART00000161346
si:ch73-281i18.3
si:ch73-281i18.3
chr17_+_25590127 1.51 ENSDART00000064803
iars2
isoleucyl-tRNA synthetase 2, mitochondrial
chr13_+_35765317 1.51 ENSDART00000100156
ENSDART00000167650
agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr12_+_23991639 1.51 ENSDART00000003143
psme4b
proteasome activator subunit 4b
chr18_+_17020967 1.50 ENSDART00000189168
chtf8
CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
chr13_+_24834199 1.50 ENSDART00000101274
zgc:153981
zgc:153981
chr4_+_17245217 1.50 ENSDART00000184215
ENSDART00000110908
casc1
cancer susceptibility candidate 1
chr15_-_26887028 1.49 ENSDART00000156292
si:dkey-243i1.1
si:dkey-243i1.1
chr19_+_20274264 1.48 ENSDART00000183513
oxnad1
oxidoreductase NAD-binding domain containing 1
chr11_+_27364059 1.47 ENSDART00000172883
fbln2
fibulin 2
chr21_+_17005737 1.45 ENSDART00000101246
vps29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr2_-_42492445 1.45 ENSDART00000139929
esyt2a
extended synaptotagmin-like protein 2a
chr5_-_38170996 1.44 ENSDART00000145805
si:ch211-284e13.12
si:ch211-284e13.12
chr6_+_11680726 1.44 ENSDART00000186732
calcrlb
calcitonin receptor-like b
chr24_+_26329018 1.44 ENSDART00000145752
mynn
myoneurin
chr12_-_999762 1.43 ENSDART00000127003
ENSDART00000084076
ENSDART00000152425
mettl9
methyltransferase like 9
chr1_+_45958904 1.43 ENSDART00000108528
arhgef7b
Rho guanine nucleotide exchange factor (GEF) 7b
chr3_-_30248277 1.43 ENSDART00000133516
ENSDART00000077029
emc10
ER membrane protein complex subunit 10
chr9_+_38043337 1.42 ENSDART00000022574
stam2
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2

Network of associatons between targets according to the STRING database.

First level regulatory network of ctcf

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.8 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
2.0 5.9 GO:0000212 meiotic spindle organization(GO:0000212)
1.5 6.1 GO:0006272 leading strand elongation(GO:0006272)
1.5 4.4 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
1.5 4.4 GO:0042373 vitamin K metabolic process(GO:0042373)
1.4 8.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
1.2 3.6 GO:1902176 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
1.2 3.6 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
1.1 5.3 GO:0043111 replication fork arrest(GO:0043111)
0.9 3.6 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.8 3.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.8 5.6 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.8 4.0 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.8 3.9 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.8 2.3 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.8 3.0 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.7 2.2 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.7 2.0 GO:0071514 genetic imprinting(GO:0071514)
0.7 8.6 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.6 2.5 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.6 2.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.6 3.6 GO:0051299 mitotic centrosome separation(GO:0007100) centrosome separation(GO:0051299)
0.6 16.9 GO:0048570 notochord morphogenesis(GO:0048570)
0.6 2.8 GO:0090527 actin filament reorganization(GO:0090527)
0.5 2.7 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.5 1.6 GO:0015074 DNA integration(GO:0015074)
0.5 3.6 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.5 9.2 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.5 1.0 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.5 2.9 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.5 1.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.5 7.0 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.5 1.8 GO:0046324 regulation of glucose import(GO:0046324)
0.4 2.9 GO:0061635 regulation of protein complex stability(GO:0061635)
0.4 2.7 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.4 2.3 GO:0035093 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.4 2.6 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.4 1.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.3 2.1 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.3 3.4 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.3 5.0 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.3 3.4 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.3 1.8 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.3 4.7 GO:0051382 kinetochore assembly(GO:0051382)
0.3 2.0 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.3 3.6 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.3 5.8 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.3 6.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.3 1.8 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.3 4.8 GO:0008078 mesodermal cell migration(GO:0008078)
0.2 3.0 GO:0007530 sex determination(GO:0007530)
0.2 6.2 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.2 1.5 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.2 5.0 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.2 5.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.2 5.1 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.2 3.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 2.7 GO:0006346 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 1.4 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.2 1.0 GO:0042264 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2 4.9 GO:0007286 spermatid development(GO:0007286) spermatid differentiation(GO:0048515)
0.2 1.4 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.2 0.6 GO:0014014 negative regulation of gliogenesis(GO:0014014) positive regulation of DNA binding(GO:0043388) negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.2 5.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 0.9 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.2 2.5 GO:0000479 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.2 1.0 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.2 1.6 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.2 5.6 GO:0006270 DNA replication initiation(GO:0006270)
0.2 3.4 GO:0001522 pseudouridine synthesis(GO:0001522)
0.2 1.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 6.7 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.2 1.8 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.2 1.5 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 1.8 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 0.6 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 1.7 GO:0045777 positive regulation of blood pressure(GO:0045777)
0.1 8.7 GO:0006414 translational elongation(GO:0006414)
0.1 2.5 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.1 0.4 GO:0006089 lactate metabolic process(GO:0006089)
0.1 3.6 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 2.7 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 1.2 GO:0016926 protein desumoylation(GO:0016926)
0.1 1.8 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.1 2.5 GO:0016180 snRNA processing(GO:0016180)
0.1 4.9 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.1 2.6 GO:0046427 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.1 1.0 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 3.8 GO:0032456 endocytic recycling(GO:0032456)
0.1 1.8 GO:0006298 mismatch repair(GO:0006298)
0.1 0.3 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 0.4 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.1 0.9 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) establishment of mitochondrion localization(GO:0051654)
0.1 1.0 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 1.3 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 2.8 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 2.9 GO:0048794 swim bladder development(GO:0048794)
0.1 3.2 GO:0051057 positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.1 0.8 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.1 1.8 GO:0007520 myoblast fusion(GO:0007520)
0.1 1.6 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 3.4 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 1.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 2.2 GO:0030488 tRNA methylation(GO:0030488)
0.1 1.7 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 5.1 GO:0050657 nucleic acid transport(GO:0050657) RNA transport(GO:0050658) establishment of RNA localization(GO:0051236)
0.1 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 1.5 GO:0007099 centriole replication(GO:0007099)
0.0 1.2 GO:0090148 membrane fission(GO:0090148)
0.0 2.0 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 1.1 GO:0070831 basement membrane assembly(GO:0070831)
0.0 1.4 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 1.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 2.5 GO:0034968 histone lysine methylation(GO:0034968)
0.0 4.1 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.3 GO:0010212 response to ionizing radiation(GO:0010212)
0.0 2.9 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 3.4 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 0.4 GO:0099560 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988) synaptic membrane adhesion(GO:0099560)
0.0 1.0 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.0 0.9 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 3.0 GO:0006413 translational initiation(GO:0006413)
0.0 2.1 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.1 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 3.8 GO:0032259 methylation(GO:0032259)
0.0 2.8 GO:0006364 rRNA processing(GO:0006364)
0.0 6.0 GO:0008380 RNA splicing(GO:0008380)
0.0 0.8 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.9 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.8 GO:0048247 monocyte chemotaxis(GO:0002548) lymphocyte chemotaxis(GO:0048247)
0.0 1.1 GO:0006473 protein acetylation(GO:0006473)
0.0 0.1 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 4.1 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.7 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)
0.0 1.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 5.0 GO:0051301 cell division(GO:0051301)
0.0 0.5 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 1.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.8 GO:0098661 inorganic anion transmembrane transport(GO:0098661)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
1.3 6.7 GO:0005673 transcription factor TFIIE complex(GO:0005673)
1.2 3.6 GO:0019185 snRNA-activating protein complex(GO:0019185)
1.1 4.4 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
1.1 5.3 GO:0031298 replication fork protection complex(GO:0031298)
1.0 5.9 GO:0032133 chromosome passenger complex(GO:0032133)
0.9 5.6 GO:0005784 Sec61 translocon complex(GO:0005784)
0.9 4.6 GO:0097433 dense body(GO:0097433)
0.8 7.0 GO:0016272 prefoldin complex(GO:0016272)
0.7 8.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.6 3.7 GO:0031262 Ndc80 complex(GO:0031262)
0.6 2.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.6 6.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.6 2.2 GO:0070209 ASTRA complex(GO:0070209)
0.5 1.6 GO:0034709 methylosome(GO:0034709)
0.5 2.6 GO:0031415 NatA complex(GO:0031415)
0.4 2.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.4 6.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.4 3.3 GO:0031526 brush border membrane(GO:0031526)
0.4 7.9 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.3 3.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.3 3.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.3 1.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.3 6.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 2.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 1.8 GO:0061700 GATOR2 complex(GO:0061700)
0.2 1.6 GO:0071818 BAT3 complex(GO:0071818)
0.2 1.8 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.2 1.3 GO:0070876 SOSS complex(GO:0070876)
0.2 1.4 GO:0030914 STAGA complex(GO:0030914)
0.2 0.6 GO:0043220 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.2 1.3 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.2 1.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 2.0 GO:0008180 COP9 signalosome(GO:0008180)
0.2 1.8 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.2 1.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.2 2.3 GO:0005682 U5 snRNP(GO:0005682)
0.1 2.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 2.5 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 3.1 GO:0005771 multivesicular body(GO:0005771)
0.1 1.4 GO:0030904 retromer complex(GO:0030904)
0.1 2.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 2.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 2.5 GO:0032039 integrator complex(GO:0032039)
0.1 2.1 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 0.8 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 4.9 GO:0016592 mediator complex(GO:0016592)
0.1 3.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 2.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 4.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 3.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.7 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.2 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.2 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 1.8 GO:0030496 midbody(GO:0030496)
0.1 0.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 4.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.9 GO:0044545 NSL complex(GO:0044545)
0.0 3.1 GO:0005814 centriole(GO:0005814)
0.0 2.5 GO:0005643 nuclear pore(GO:0005643)
0.0 10.1 GO:0005819 spindle(GO:0005819)
0.0 4.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 5.1 GO:0005769 early endosome(GO:0005769)
0.0 1.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.9 GO:0000145 exocyst(GO:0000145)
0.0 4.0 GO:0005681 spliceosomal complex(GO:0005681)
0.0 2.7 GO:0016607 nuclear speck(GO:0016607)
0.0 6.9 GO:0005730 nucleolus(GO:0005730)
0.0 2.8 GO:0005925 focal adhesion(GO:0005925)
0.0 2.0 GO:0031201 SNARE complex(GO:0031201)
0.0 2.5 GO:0043296 apical junction complex(GO:0043296)
0.0 9.0 GO:1990904 ribonucleoprotein complex(GO:1990904)
0.0 10.9 GO:0005654 nucleoplasm(GO:0005654)
0.0 0.6 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 1.0 GO:0031514 motile cilium(GO:0031514)
0.0 3.5 GO:0005874 microtubule(GO:0005874)
0.0 1.1 GO:0005604 basement membrane(GO:0005604)
0.0 1.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.7 GO:0000502 proteasome complex(GO:0000502)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0071532 ankyrin repeat binding(GO:0071532)
1.2 4.8 GO:0051059 NF-kappaB binding(GO:0051059)
1.1 3.3 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.9 2.8 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.9 4.6 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.9 3.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.8 5.9 GO:0035173 histone kinase activity(GO:0035173)
0.7 3.6 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.6 2.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.5 8.2 GO:0022884 macromolecule transmembrane transporter activity(GO:0022884)
0.5 1.9 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.5 1.8 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.5 6.8 GO:2001069 glycogen binding(GO:2001069)
0.4 4.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.4 7.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.4 2.7 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.4 2.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.4 1.1 GO:0001605 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.4 5.9 GO:0016018 cyclosporin A binding(GO:0016018)
0.3 3.6 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3 2.7 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.3 1.7 GO:0004960 thromboxane receptor activity(GO:0004960)
0.3 0.8 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.3 1.8 GO:0070728 leucine binding(GO:0070728)
0.3 1.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.3 1.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2 2.3 GO:0016504 peptidase activator activity(GO:0016504)
0.2 0.9 GO:0030626 U12 snRNA binding(GO:0030626)
0.2 1.8 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 6.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 1.1 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.2 4.4 GO:0048038 quinone binding(GO:0048038)
0.2 2.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 5.1 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.2 8.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 1.5 GO:0015232 heme transporter activity(GO:0015232)
0.2 7.0 GO:0051087 chaperone binding(GO:0051087)
0.2 1.4 GO:0032977 membrane insertase activity(GO:0032977)
0.1 0.6 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 4.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 2.5 GO:0002039 p53 binding(GO:0002039)
0.1 1.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 2.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 0.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 1.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 2.5 GO:0010181 FMN binding(GO:0010181)
0.1 2.5 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.1 1.9 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.0 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 3.0 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 1.0 GO:0005042 netrin receptor activity(GO:0005042)
0.1 8.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 1.7 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 6.2 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 4.4 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 1.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 2.5 GO:0035064 methylated histone binding(GO:0035064)
0.1 5.0 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 14.2 GO:0046982 protein heterodimerization activity(GO:0046982)
0.1 1.0 GO:0050811 GABA receptor binding(GO:0050811)
0.1 3.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.9 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 1.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 4.9 GO:0042803 protein homodimerization activity(GO:0042803)
0.1 3.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.8 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 2.0 GO:0005109 frizzled binding(GO:0005109)
0.0 1.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.8 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.4 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.8 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 1.0 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 3.0 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 3.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.8 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 2.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 2.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.8 GO:0051020 GTPase binding(GO:0051020)
0.0 1.2 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 2.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 4.4 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.8 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 1.3 GO:0019902 phosphatase binding(GO:0019902)
0.0 1.1 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 4.4 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 3.8 GO:0008168 methyltransferase activity(GO:0008168)
0.0 4.5 GO:0003682 chromatin binding(GO:0003682)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 42.5 GO:0003677 DNA binding(GO:0003677)
0.0 2.1 GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 0.9 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 6.4 GO:0005525 GTP binding(GO:0005525)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 9.3 GO:0003723 RNA binding(GO:0003723)
0.0 0.8 GO:0015296 anion:cation symporter activity(GO:0015296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.7 PID BARD1 PATHWAY BARD1 signaling events
0.2 8.3 PID ATR PATHWAY ATR signaling pathway
0.2 13.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.2 5.9 PID AURORA A PATHWAY Aurora A signaling
0.2 6.7 PID P53 REGULATION PATHWAY p53 pathway
0.2 4.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 1.2 PID ATM PATHWAY ATM pathway
0.1 2.9 PID PLK1 PATHWAY PLK1 signaling events
0.1 4.0 PID CMYB PATHWAY C-MYB transcription factor network
0.1 4.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 1.7 ST GA13 PATHWAY G alpha 13 Pathway
0.0 1.0 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 4.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.6 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.8 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.5 6.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.5 4.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.4 5.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.4 10.0 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.4 2.1 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.3 1.7 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.3 6.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.3 1.8 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.3 4.4 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.2 5.1 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.2 9.1 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2 2.1 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.2 3.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 6.1 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.2 1.8 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 4.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 3.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 7.7 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 1.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.0 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 2.5 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 0.8 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 0.8 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 1.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.6 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 3.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 2.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 2.3 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases