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PRJEB1986: zebrafish developmental stages transcriptome

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Results for ddx28+nfatc1+nfatc2b+nfatc3a+nfatc3b+nfatc4

Z-value: 0.89

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Transcription factors associated with ddx28+nfatc1+nfatc2b+nfatc3a+nfatc3b+nfatc4

Gene Symbol Gene ID Gene Info
nfatc1
ENSDARG00000036168 nuclear factor of activated T cells 1
nfatc3b
ENSDARG00000051729 nuclear factor of activated T cells 3b
nfatc4
ENSDARG00000054162 nuclear factor of activated T cells 4
nfatc3a
ENSDARG00000076297 nuclear factor of activated T cells 3a
nfatc2b
ENSDARG00000079972 nuclear factor of activated T cells 2b
ddx28
ENSDARG00000112133 nuclear factor of activated T cells 3a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nfatc2bdr11_v1_chr6_-_55254786_552547860.831.2e-05Click!
nfatc3bdr11_v1_chr25_-_36248053_362480530.812.7e-05Click!
nfatc1dr11_v1_chr19_+_22216778_222167780.789.2e-05Click!
nfatc4dr11_v1_chr2_-_37797577_37797577-0.493.2e-02Click!
nfatc3adr11_v1_chr7_-_34927961_349279610.341.5e-01Click!

Activity profile of ddx28+nfatc1+nfatc2b+nfatc3a+nfatc3b+nfatc4 motif

Sorted Z-values of ddx28+nfatc1+nfatc2b+nfatc3a+nfatc3b+nfatc4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_42063906 2.87 ENSDART00000048893
pcbp3
poly(rC) binding protein 3
chr19_-_5125663 1.97 ENSDART00000005547
ENSDART00000132642
gnb3b
guanine nucleotide binding protein (G protein), beta polypeptide 3b
chr17_+_51499789 1.95 ENSDART00000187701
CABZ01067581.1

chr17_+_27456804 1.77 ENSDART00000017756
ENSDART00000181461
ENSDART00000180178
ctsl.1
cathepsin L.1
chr8_+_22931427 1.75 ENSDART00000063096
sypa
synaptophysin a
chr20_+_46040666 1.75 ENSDART00000060744
si:dkey-7c18.24
si:dkey-7c18.24
chr13_+_32740509 1.74 ENSDART00000076423
ENSDART00000160138
sobpa
sine oculis binding protein homolog (Drosophila) a
chr17_+_33340675 1.73 ENSDART00000184396
ENSDART00000077553
xdh
xanthine dehydrogenase
chr12_-_32421046 1.73 ENSDART00000075567
enpp7.1
ectonucleotide pyrophosphatase/phosphodiesterase 7, tandem duplicate 1
chr12_+_46960579 1.64 ENSDART00000149032
oat
ornithine aminotransferase
chr16_+_45739193 1.60 ENSDART00000184852
ENSDART00000156851
ENSDART00000154704
paqr6
progestin and adipoQ receptor family member VI
chr11_-_24191928 1.59 ENSDART00000136827
sox12
SRY (sex determining region Y)-box 12
chr16_+_45746549 1.58 ENSDART00000190403
paqr6
progestin and adipoQ receptor family member VI
chr3_-_61181018 1.50 ENSDART00000187970
pvalb4
parvalbumin 4
chr13_+_27073901 1.49 ENSDART00000146227
slc24a3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr3_+_9332984 1.45 ENSDART00000185184
ENSDART00000183535
LO018550.2

chr21_-_26250443 1.39 ENSDART00000123713
gria1b
glutamate receptor, ionotropic, AMPA 1b
chr20_-_53624645 1.36 ENSDART00000083427
ENSDART00000152920
slc25a29
solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29
chr6_-_10233538 1.35 ENSDART00000182004
ENSDART00000149237
ENSDART00000148876
xirp2a
xin actin binding repeat containing 2a
chr11_-_37359416 1.31 ENSDART00000159184
erc2
ELKS/RAB6-interacting/CAST family member 2
chr21_+_11401247 1.30 ENSDART00000143952
cel.1
carboxyl ester lipase, tandem duplicate 1
chr24_+_35975398 1.30 ENSDART00000173058
obscnb
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b
chr12_-_31103187 1.30 ENSDART00000005562
ENSDART00000031408
ENSDART00000125046
ENSDART00000009237
ENSDART00000122972
ENSDART00000153068
tcf7l2
transcription factor 7 like 2
chr16_+_4055331 1.26 ENSDART00000128978
CR391998.1

chr6_-_48094342 1.23 ENSDART00000137458
slc2a1b
solute carrier family 2 (facilitated glucose transporter), member 1b
chr3_-_41791178 1.22 ENSDART00000049687
grifin
galectin-related inter-fiber protein
chr2_-_37353098 1.16 ENSDART00000056522
skila
SKI-like proto-oncogene a
chr3_-_5067585 1.13 ENSDART00000169609
tefb
thyrotrophic embryonic factor b
chr17_+_30448452 1.11 ENSDART00000153939
lpin1
lipin 1
chr9_+_31752628 1.10 ENSDART00000060054
itgbl1
integrin, beta-like 1
chr16_-_13613475 1.09 ENSDART00000139102
dbpb
D site albumin promoter binding protein b
chr4_+_61995745 1.09 ENSDART00000171539
CT990567.1

chr6_+_10450000 1.07 ENSDART00000151288
ENSDART00000187431
ENSDART00000192474
ENSDART00000188214
ENSDART00000184766
ENSDART00000190082
kcnh7
potassium channel, voltage gated eag related subfamily H, member 7
chr9_+_13682133 1.07 ENSDART00000175639
mpp4a
membrane protein, palmitoylated 4a (MAGUK p55 subfamily member 4)
chr8_+_37489495 1.06 ENSDART00000141516
fmodb
fibromodulin b
chr9_-_42989297 1.06 ENSDART00000126871
ttn.2
titin, tandem duplicate 2
chr2_+_33541928 1.06 ENSDART00000162852
BX548164.1

chr3_+_14463941 1.05 ENSDART00000170927
cnn1b
calponin 1, basic, smooth muscle, b
chr8_-_21268303 1.05 ENSDART00000067211
gpr37l1b
G protein-coupled receptor 37 like 1b
chr12_-_15205087 1.04 ENSDART00000010068
sult1st6
sulfotransferase family 1, cytosolic sulfotransferase 6
chr12_-_26064480 1.04 ENSDART00000158215
ENSDART00000171206
ENSDART00000171212
ENSDART00000182956
ENSDART00000186779
ldb3b
LIM domain binding 3b
chr20_+_6142433 1.03 ENSDART00000054084
ENSDART00000136986
ttr
transthyretin (prealbumin, amyloidosis type I)
chr23_-_7826849 1.01 ENSDART00000157612
myt1b
myelin transcription factor 1b
chr9_-_30190513 1.01 ENSDART00000137083
impg2a
interphotoreceptor matrix proteoglycan 2a
chr6_+_6491013 1.00 ENSDART00000140827
bcl11ab
B cell CLL/lymphoma 11Ab
chr8_+_53464216 1.00 ENSDART00000169514
cacna1db
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr13_-_298454 0.99 ENSDART00000135782
chs1
chitin synthase 1
chr4_+_76926059 0.97 ENSDART00000136192
si:dkey-240n22.6
si:dkey-240n22.6
chr1_+_19332837 0.97 ENSDART00000078594
tyrp1b
tyrosinase-related protein 1b
chr22_+_19311411 0.97 ENSDART00000133234
ENSDART00000138284
si:dkey-21e2.16
si:dkey-21e2.16
chr15_+_30158652 0.97 ENSDART00000190682
nlk2
nemo-like kinase, type 2
chr1_-_47089818 0.97 ENSDART00000132378
itsn1
intersectin 1 (SH3 domain protein)
chr17_+_13763425 0.96 ENSDART00000105175
lrfn5a
leucine rich repeat and fibronectin type III domain containing 5a
chr12_-_31461219 0.95 ENSDART00000148954
acsl5
acyl-CoA synthetase long chain family member 5
chr13_+_1575276 0.94 ENSDART00000165987
DST
dystonin
chr12_+_19401854 0.94 ENSDART00000153415
si:dkey-16i5.8
si:dkey-16i5.8
chr2_-_13216269 0.94 ENSDART00000149947
bcl2b
BCL2, apoptosis regulator b
chr6_+_53349966 0.92 ENSDART00000167079
si:ch211-161c3.5
si:ch211-161c3.5
chr1_-_5455498 0.91 ENSDART00000040368
ENSDART00000114035
mnx2b
motor neuron and pancreas homeobox 2b
chr16_+_14033121 0.91 ENSDART00000135844
rusc1
RUN and SH3 domain containing 1
chr2_-_22927958 0.90 ENSDART00000141621
myo7bb
myosin VIIBb
chr10_-_35236949 0.89 ENSDART00000145804
ypel2a
yippee-like 2a
chr4_+_19535946 0.89 ENSDART00000192342
ENSDART00000183740
ENSDART00000180812
ENSDART00000180017
lrrc4.1
leucine rich repeat containing 4.1
chr15_-_6404443 0.88 ENSDART00000098038
dscamb
Down syndrome cell adhesion molecule b
chr20_-_39789036 0.87 ENSDART00000086405
ENSDART00000098253
rnf217
ring finger protein 217
chr17_+_36627099 0.86 ENSDART00000154104
impg1b
interphotoreceptor matrix proteoglycan 1b
chr6_-_57539141 0.85 ENSDART00000156967
itcha
itchy E3 ubiquitin protein ligase a
chr18_+_3630331 0.85 ENSDART00000159059
lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr4_+_23223881 0.85 ENSDART00000133056
ENSDART00000089126
trhde.1
thyrotropin releasing hormone degrading enzyme, tandem duplicate 1
chr25_+_14087045 0.85 ENSDART00000155770
actc1c
actin, alpha, cardiac muscle 1c
chr15_-_34845414 0.84 ENSDART00000009892
gabbr1a
gamma-aminobutyric acid (GABA) B receptor, 1a
chr2_+_7192966 0.84 ENSDART00000142735
si:ch211-13f8.1
si:ch211-13f8.1
chr20_+_1996202 0.83 ENSDART00000184143
CABZ01092781.1

chr21_-_21096437 0.83 ENSDART00000186552
ank1b
ankyrin 1, erythrocytic b
chr5_-_23277939 0.83 ENSDART00000003514
plp1b
proteolipid protein 1b
chr11_-_37425407 0.83 ENSDART00000160911
erc2
ELKS/RAB6-interacting/CAST family member 2
chr1_+_19616799 0.80 ENSDART00000143077
fbxo10
F-box protein 10
chr15_+_16525126 0.80 ENSDART00000193455
galnt17
polypeptide N-acetylgalactosaminyltransferase 17
chr19_-_4851411 0.79 ENSDART00000110398
fbxl20
F-box and leucine-rich repeat protein 20
chr17_-_19828505 0.79 ENSDART00000154745
fmn2a
formin 2a
chr8_-_4327473 0.79 ENSDART00000134378
cux2b
cut-like homeobox 2b
chr11_-_32723851 0.78 ENSDART00000155592
pcdh17
protocadherin 17
chr2_-_22927581 0.77 ENSDART00000109515
myo7bb
myosin VIIBb
chr10_-_42685512 0.76 ENSDART00000081347
stc1l
stanniocalcin 1, like
chr12_+_31713239 0.76 ENSDART00000122379
habp2
hyaluronan binding protein 2
chr14_-_2369849 0.76 ENSDART00000180422
ENSDART00000189731
ENSDART00000111748
pcdhb
protocadherin b
chr9_-_23994225 0.76 ENSDART00000140346
col6a3
collagen, type VI, alpha 3
chr16_+_46430627 0.76 ENSDART00000127681
rpz6
rapunzel 6
chr19_-_15335787 0.76 ENSDART00000187131
hivep3a
human immunodeficiency virus type I enhancer binding protein 3a
chr12_+_33403694 0.75 ENSDART00000124083
fasn
fatty acid synthase
chr9_+_54290896 0.75 ENSDART00000149175
pou4f3
POU class 4 homeobox 3
chr9_-_23990416 0.75 ENSDART00000113176
col6a3
collagen, type VI, alpha 3
chr5_+_6755466 0.75 ENSDART00000163247
ENSDART00000114293
areg
amphiregulin
chr4_-_23083187 0.75 ENSDART00000009768
magi2a
membrane associated guanylate kinase, WW and PDZ domain containing 2a
chr14_-_448182 0.75 ENSDART00000180018
FAT4
FAT atypical cadherin 4
chr9_-_35069645 0.74 ENSDART00000122679
ENSDART00000077908
ENSDART00000077894
ENSDART00000125536
appb
amyloid beta (A4) precursor protein b
chr14_-_33454595 0.74 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
tmem255a
transmembrane protein 255A
chr6_-_46398584 0.74 ENSDART00000193098
camk1a
calcium/calmodulin-dependent protein kinase Ia
chr18_+_41495841 0.74 ENSDART00000098671
si:ch211-203b8.6
si:ch211-203b8.6
chr10_+_34623183 0.73 ENSDART00000114630
nbeaa
neurobeachin a
chr7_+_18176162 0.73 ENSDART00000109171
rce1a
Ras converting CAAX endopeptidase 1a
chr5_+_51443009 0.73 ENSDART00000083350
rasgrf2b
Ras protein-specific guanine nucleotide-releasing factor 2b
chr19_+_5674907 0.73 ENSDART00000042189
pdk2b
pyruvate dehydrogenase kinase, isozyme 2b
chr25_+_336503 0.73 ENSDART00000160395
CU929262.1

chr2_-_37352514 0.72 ENSDART00000140498
ENSDART00000186422
skila
SKI-like proto-oncogene a
chr1_+_37391141 0.72 ENSDART00000083593
ENSDART00000168647
sparcl1
SPARC-like 1
chr19_+_43392446 0.72 ENSDART00000147290
yrk
Yes-related kinase
chr20_+_23173710 0.71 ENSDART00000074172
sgcb
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr8_+_7144066 0.71 ENSDART00000146306
slc6a6a
solute carrier family 6 (neurotransmitter transporter), member 6a
chr1_+_38858399 0.70 ENSDART00000165454
CU915762.1

chr5_-_30418636 0.70 ENSDART00000098285
atf5a
activating transcription factor 5a
chr24_-_21588914 0.70 ENSDART00000152054
gpr12
G protein-coupled receptor 12
chr3_-_30434016 0.70 ENSDART00000150958
lrrc4ba
leucine rich repeat containing 4Ba
chr21_-_26250744 0.69 ENSDART00000044735
gria1b
glutamate receptor, ionotropic, AMPA 1b
chr14_-_36345175 0.69 ENSDART00000077823
lrit3a
info leucine-rich repeat, immunoglobulin-like and transmembrane domains 3a
chr8_+_36948256 0.69 ENSDART00000140410
iqsec2b
IQ motif and Sec7 domain 2b
chr20_-_18731268 0.69 ENSDART00000183893
enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr6_-_55254786 0.68 ENSDART00000113805
nfatc2b
nuclear factor of activated T cells 2b
chr4_+_19534833 0.68 ENSDART00000140028
lrrc4.1
leucine rich repeat containing 4.1
chr16_+_48714048 0.68 ENSDART00000148709
ENSDART00000150121
brd2b
bromodomain containing 2b
chr2_+_53357953 0.67 ENSDART00000187577
celf5b
cugbp, Elav-like family member 5b
chr14_-_47314011 0.67 ENSDART00000178523
fstl5
follistatin-like 5
chr21_+_40417152 0.67 ENSDART00000171244
ssh2b
slingshot protein phosphatase 2b
chr2_+_42191592 0.67 ENSDART00000144716
cavin4a
caveolae associated protein 4a
chr8_-_34051548 0.67 ENSDART00000105204
pbx3b
pre-B-cell leukemia homeobox 3b
chr25_+_27493444 0.67 ENSDART00000112299
gpr37a
G protein-coupled receptor 37a
chr6_+_10534752 0.67 ENSDART00000090874
kcnh7
potassium channel, voltage gated eag related subfamily H, member 7
chr1_-_38816685 0.67 ENSDART00000075230
asb5b
ankyrin repeat and SOCS box containing 5b
chr2_+_49246099 0.66 ENSDART00000179089
sema6ba
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba
chr16_+_30117798 0.65 ENSDART00000135723
ENSDART00000000198
sema6e
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E
chr25_-_17395315 0.65 ENSDART00000064596
cyp2x8
cytochrome P450, family 2, subfamily X, polypeptide 8
chr20_-_9273669 0.64 ENSDART00000175069
syt14b
synaptotagmin XIVb
chr14_+_40874608 0.64 ENSDART00000168448
si:ch211-106m9.1
si:ch211-106m9.1
chr3_+_22059066 0.63 ENSDART00000155739
kansl1b
KAT8 regulatory NSL complex subunit 1b
chr2_+_53359234 0.62 ENSDART00000147581
celf5b
cugbp, Elav-like family member 5b
chr12_-_28537615 0.61 ENSDART00000067762
MYO1D
si:ch211-94l19.4
chr9_-_11263228 0.61 ENSDART00000113847
chpfa
chondroitin polymerizing factor a
chr14_-_2400668 0.61 ENSDART00000172717
ENSDART00000182882
si:ch73-233f7.1
si:ch73-233f7.1
chr8_+_50985798 0.61 ENSDART00000177963
si:dkey-32e23.4
si:dkey-32e23.4
chr7_+_56889879 0.61 ENSDART00000039810
myo9aa
myosin IXAa
chr11_+_24819624 0.61 ENSDART00000155514
kdm5ba
lysine (K)-specific demethylase 5Ba
chr6_-_49078702 0.61 ENSDART00000135185
slc5a8l
solute carrier family 5 (iodide transporter), member 8-like
chr16_-_12787029 0.60 ENSDART00000139916
foxj2
forkhead box J2
chr19_-_46775562 0.60 ENSDART00000187144
abrab
actin binding Rho activating protein b
chr1_-_59415948 0.60 ENSDART00000168614
si:ch211-188p14.4
si:ch211-188p14.4
chr8_-_7637626 0.60 ENSDART00000123882
ENSDART00000040672
mecp2
methyl CpG binding protein 2
chr5_-_40910749 0.60 ENSDART00000083467
ENSDART00000133183
parp8
poly (ADP-ribose) polymerase family, member 8
chr6_-_40899618 0.59 ENSDART00000153949
ENSDART00000021969
zgc:172271
zgc:172271
chr6_+_27667359 0.59 ENSDART00000159624
ENSDART00000049177
rab6ba
RAB6B, member RAS oncogene family a
chr19_-_6193448 0.59 ENSDART00000151405
erf
Ets2 repressor factor
chr1_-_21599219 0.59 ENSDART00000148327
adamtsl7
ADAMTS-like 7
chr14_+_6429399 0.59 ENSDART00000149783
ENSDART00000148461
abca1b
ATP-binding cassette, sub-family A (ABC1), member 1B
chr14_+_4178236 0.59 ENSDART00000162015
slc25a51b
solute carrier family 25, member 51b
chr7_+_33279108 0.58 ENSDART00000084530
coro2ba
coronin, actin binding protein, 2Ba
chr5_-_15851953 0.58 ENSDART00000173101
si:dkey-1k23.3
si:dkey-1k23.3
chr10_-_2682198 0.58 ENSDART00000183727
pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr20_-_37522569 0.58 ENSDART00000177011
ENSDART00000058502
hivep2a
human immunodeficiency virus type I enhancer binding protein 2a
chr7_-_11605185 0.58 ENSDART00000169291
ENSDART00000113904
stard5
StAR-related lipid transfer (START) domain containing 5
chr3_-_34279109 0.57 ENSDART00000183255
tnrc6c1
trinucleotide repeat containing 6C1
chr20_-_49681850 0.57 ENSDART00000025926
col12a1b
collagen, type XII, alpha 1b
chr10_-_23358357 0.57 ENSDART00000135475
cadm2a
cell adhesion molecule 2a
chr19_+_3056450 0.57 ENSDART00000141324
ENSDART00000082353
hsf1
heat shock transcription factor 1
chr3_-_28209001 0.57 ENSDART00000151178
rbfox1
RNA binding fox-1 homolog 1
chr13_+_16521898 0.57 ENSDART00000122557
kcnma1a
potassium large conductance calcium-activated channel, subfamily M, alpha member 1a
chr14_-_493029 0.56 ENSDART00000115093
zgc:172215
zgc:172215
chr2_-_48966431 0.56 ENSDART00000147948
kcnj9
potassium inwardly-rectifying channel, subfamily J, member 9
chr8_-_38403018 0.56 ENSDART00000134100
sorbs3
sorbin and SH3 domain containing 3
chr4_-_23643272 0.56 ENSDART00000112301
ENSDART00000133184
trhde.2
thyrotropin releasing hormone degrading enzyme, tandem duplicate 2
chr10_+_35468978 0.55 ENSDART00000131984
phldb2a
pleckstrin homology-like domain, family B, member 2a
chr20_-_25533739 0.55 ENSDART00000063064
cyp2ad6
cytochrome P450, family 2, subfamily AD, polypeptide 6
chr2_-_14390627 0.55 ENSDART00000172367
sgip1b
SH3-domain GRB2-like (endophilin) interacting protein 1b
chr3_-_32817274 0.55 ENSDART00000142582
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr16_-_17541890 0.55 ENSDART00000131328
clcn1b
chloride channel, voltage-sensitive 1b
chr23_-_32892441 0.54 ENSDART00000147998
plxna2
plexin A2
chr3_+_12593558 0.53 ENSDART00000186891
ENSDART00000159252
abca3b
ATP-binding cassette, sub-family A (ABC1), member 3b
chr17_-_45247332 0.53 ENSDART00000016815
ttbk2a
tau tubulin kinase 2a
chr1_-_49409549 0.53 ENSDART00000074317
GSK3B (1 of many)
si:dkeyp-80c12.7
chr25_-_16818978 0.53 ENSDART00000104140
dyrk4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr19_-_10243148 0.53 ENSDART00000148073
shisa7b
shisa family member 7
chr6_+_36807861 0.53 ENSDART00000161708
si:ch73-29l19.1
si:ch73-29l19.1
chr18_+_25546227 0.53 ENSDART00000085824
pex11a
peroxisomal biogenesis factor 11 alpha
chr20_+_31287356 0.52 ENSDART00000007688
slc22a16
solute carrier family 22 (organic cation/carnitine transporter), member 16
chr22_+_20461488 0.51 ENSDART00000135984
onecut3a
one cut homeobox 3a
chr24_+_15897717 0.51 ENSDART00000105956
neto1l
neuropilin (NRP) and tolloid (TLL)-like 1, like
chr25_+_4837915 0.51 ENSDART00000168016
gnb5a
guanine nucleotide binding protein (G protein), beta 5a
chr14_+_19258702 0.51 ENSDART00000187087
ENSDART00000005738
slitrk2
SLIT and NTRK-like family, member 2
chr10_-_22249444 0.51 ENSDART00000148831
fgf11b
fibroblast growth factor 11b
chr4_-_12102025 0.50 ENSDART00000048391
ENSDART00000023894
braf
B-Raf proto-oncogene, serine/threonine kinase
chr13_+_10945337 0.50 ENSDART00000091845
abcg5
ATP-binding cassette, sub-family G (WHITE), member 5
chr24_+_15670013 0.50 ENSDART00000185826
CU929414.1

chr21_-_2814709 0.50 ENSDART00000097664
SEMA4D
semaphorin 4D
chr10_-_29903165 0.50 ENSDART00000078800
lim2.1
lens intrinsic membrane protein 2.1
chr17_-_45247151 0.50 ENSDART00000186230
ttbk2a
tau tubulin kinase 2a
chr14_-_3174570 0.49 ENSDART00000163585
csf1ra
colony stimulating factor 1 receptor, a
chr4_-_75707991 0.49 ENSDART00000166358
ENSDART00000160021
si:dkey-165o8.2
si:dkey-165o8.2
chr23_+_37579107 0.49 ENSDART00000169376
plekhg5b
pleckstrin homology domain containing, family G (with RhoGef domain) member 5b
chr2_-_31634978 0.49 ENSDART00000135668
si:ch211-106h4.9
si:ch211-106h4.9
chr6_+_45347219 0.49 ENSDART00000188240
LO017951.1

chr15_-_20933574 0.49 ENSDART00000152648
ENSDART00000152448
ENSDART00000152244
usp2a
ubiquitin specific peptidase 2a
chr14_+_41490821 0.49 ENSDART00000173319
chrnb2l
cholinergic receptor, nicotinic, beta 2, like

Network of associatons between targets according to the STRING database.

First level regulatory network of ddx28+nfatc1+nfatc2b+nfatc3a+nfatc3b+nfatc4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.3 1.4 GO:0006844 acyl carnitine transport(GO:0006844)
0.3 1.3 GO:0010226 response to lithium ion(GO:0010226)
0.3 1.0 GO:2000193 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.3 1.0 GO:0003322 pancreatic A cell development(GO:0003322)
0.3 1.0 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.2 0.7 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.2 1.0 GO:0006031 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.2 2.1 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.2 1.0 GO:0097066 response to thyroid hormone(GO:0097066)
0.2 1.6 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.2 0.5 GO:0003403 optic vesicle formation(GO:0003403)
0.2 1.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 0.5 GO:0015695 organic cation transport(GO:0015695)
0.2 0.6 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 0.5 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.6 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.1 0.4 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.5 GO:0016559 peroxisome fission(GO:0016559)
0.1 1.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.1 0.5 GO:0071675 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) regulation of odontogenesis(GO:0042481) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.1 0.6 GO:1903146 regulation of mitophagy(GO:1903146)
0.1 0.6 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.1 0.4 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 1.3 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.5 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.4 GO:0021755 eurydendroid cell differentiation(GO:0021755)
0.1 1.0 GO:0072337 modified amino acid transport(GO:0072337)
0.1 0.4 GO:0090299 regulation of neural crest formation(GO:0090299)
0.1 0.4 GO:0051148 negative regulation of muscle cell differentiation(GO:0051148)
0.1 0.3 GO:0071926 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.1 0.4 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.1 0.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.5 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 1.9 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.3 GO:0014909 smooth muscle cell migration(GO:0014909)
0.1 0.4 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.3 GO:0044246 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246)
0.1 0.9 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.9 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 0.3 GO:0060405 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.1 0.3 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 1.1 GO:0048769 sarcomerogenesis(GO:0048769)
0.1 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 0.3 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.3 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.1 0.6 GO:0050975 sensory perception of touch(GO:0050975)
0.1 0.6 GO:0033700 phospholipid efflux(GO:0033700)
0.1 0.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.4 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 0.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.3 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 0.4 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 0.5 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.4 GO:0051013 microtubule severing(GO:0051013)
0.0 0.4 GO:1901998 toxin transport(GO:1901998)
0.0 0.4 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.3 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.9 GO:0007634 optokinetic behavior(GO:0007634)
0.0 1.0 GO:0051923 sulfation(GO:0051923)
0.0 0.3 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.5 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.6 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 1.1 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.9 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.3 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 0.7 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.9 GO:0097192 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 0.6 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.9 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.4 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:1901490 regulation of lymphangiogenesis(GO:1901490)
0.0 4.6 GO:0048675 axon extension(GO:0048675)
0.0 0.4 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.6 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.6 GO:0009408 response to heat(GO:0009408)
0.0 2.6 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.0 0.1 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 1.5 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.7 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 1.2 GO:0039021 pronephric glomerulus development(GO:0039021)
0.0 0.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.7 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 1.2 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.3 GO:0016556 mRNA modification(GO:0016556)
0.0 2.1 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0070293 renal absorption(GO:0070293)
0.0 0.1 GO:1902667 regulation of axon guidance(GO:1902667)
0.0 0.3 GO:0048070 regulation of developmental pigmentation(GO:0048070)
0.0 0.2 GO:0030431 sleep(GO:0030431)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.4 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.1 GO:0007289 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 1.0 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.7 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.7 GO:0051494 negative regulation of cytoskeleton organization(GO:0051494)
0.0 0.2 GO:0050930 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.0 0.3 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0 0.2 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.2 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 0.3 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.6 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 4.3 GO:0034765 regulation of ion transmembrane transport(GO:0034765)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.7 GO:0045010 actin nucleation(GO:0045010)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.7 GO:0007416 synapse assembly(GO:0007416)
0.0 0.4 GO:0006826 iron ion transport(GO:0006826)
0.0 2.0 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 2.0 GO:0006816 calcium ion transport(GO:0006816)
0.0 2.4 GO:0007601 visual perception(GO:0007601)
0.0 0.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.3 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.2 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0 0.2 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.3 GO:0042446 hormone biosynthetic process(GO:0042446)
0.0 0.2 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.3 GO:0003208 cardiac ventricle morphogenesis(GO:0003208)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 1.0 GO:0021782 glial cell development(GO:0021782)
0.0 0.2 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.0 GO:1902024 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 1.4 GO:0006814 sodium ion transport(GO:0006814)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.2 1.9 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 1.0 GO:0030428 cell septum(GO:0030428)
0.1 0.8 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 1.0 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 0.4 GO:0043034 costamere(GO:0043034)
0.1 2.1 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.1 1.3 GO:0031430 M band(GO:0031430)
0.1 0.5 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 2.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.4 GO:0071914 prominosome(GO:0071914)
0.0 1.0 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.8 GO:0043209 myelin sheath(GO:0043209)
0.0 2.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0000792 heterochromatin(GO:0000792)
0.0 0.2 GO:0055087 Ski complex(GO:0055087)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.5 GO:0044545 NSL complex(GO:0044545)
0.0 0.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 1.4 GO:0008305 integrin complex(GO:0008305)
0.0 1.3 GO:0031941 filamentous actin(GO:0031941)
0.0 2.1 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 3.2 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 1.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.6 GO:0045180 basal cortex(GO:0045180)
0.0 2.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0043195 terminal bouton(GO:0043195)
0.0 1.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 1.7 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.7 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 1.1 GO:0005814 centriole(GO:0005814)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0004771 sterol esterase activity(GO:0004771)
0.4 1.2 GO:0048030 disaccharide binding(GO:0048030)
0.3 1.4 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.3 1.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 2.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.2 0.8 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.2 1.7 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.2 0.7 GO:0070699 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.2 1.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.2 1.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 2.5 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.2 0.6 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.3 GO:0031690 adrenergic receptor binding(GO:0031690)
0.1 1.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.0 GO:0004100 chitin synthase activity(GO:0004100)
0.1 2.1 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.6 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 1.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.8 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.6 GO:0032052 bile acid binding(GO:0032052)
0.1 0.3 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.3 GO:0038046 enkephalin receptor activity(GO:0038046)
0.1 0.5 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.1 0.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.1 0.6 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.5 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.1 0.8 GO:0030507 spectrin binding(GO:0030507)
0.1 0.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.6 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.2 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 1.6 GO:0008483 transaminase activity(GO:0008483)
0.1 0.5 GO:0005113 patched binding(GO:0005113)
0.1 0.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.0 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 2.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.0 0.2 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.2 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0031530 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.0 1.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 2.1 GO:0046332 SMAD binding(GO:0046332)
0.0 1.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 1.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 1.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.9 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 1.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.1 GO:0004960 thromboxane receptor activity(GO:0004960)
0.0 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.1 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.7 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 2.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.2 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.2 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.5 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.6 GO:0019957 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 1.7 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.2 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.1 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 0.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 3.2 GO:0003774 motor activity(GO:0003774)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.3 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 0.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 1.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 0.7 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.0 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.3 PID P73PATHWAY p73 transcription factor network
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.2 PID FGF PATHWAY FGF signaling pathway
0.0 0.4 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.2 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.1 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 1.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.7 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.1 1.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.0 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 0.3 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 0.4 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 0.5 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 0.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 1.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.4 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.3 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME SIGNALLING TO RAS Genes involved in Signalling to RAS
0.0 1.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis