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PRJEB1986: zebrafish developmental stages transcriptome

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Results for dlx3b

Z-value: 0.42

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Transcription factors associated with dlx3b

Gene Symbol Gene ID Gene Info
dlx3b
ENSDARG00000014626 distal-less homeobox 3b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
dlx3bdr11_v1_chr12_+_5708400_5708400-0.681.4e-03Click!

Activity profile of dlx3b motif

Sorted Z-values of dlx3b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_15546862 1.44 ENSDART00000091021
col10a1a
collagen, type X, alpha 1a
chr14_-_30587814 1.44 ENSDART00000144912
ENSDART00000149714
tmem265
transmembrane protein 265
chr15_+_47903864 1.34 ENSDART00000063835
otx5
orthodenticle homolog 5
chr25_-_32869794 1.29 ENSDART00000162784
tmem266
transmembrane protein 266
chr11_+_30244356 1.24 ENSDART00000036050
ENSDART00000150080
rs1a
retinoschisin 1a
chr16_+_5774977 1.11 ENSDART00000134202
ccka
cholecystokinin a
chr3_-_31079186 1.09 ENSDART00000145636
ENSDART00000140569
ELOB (1 of many)
elob
elongin B
elongin B
chr25_+_29160102 1.08 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr3_-_21280373 1.00 ENSDART00000003939
syngr1a
synaptogyrin 1a
chr21_-_10488379 0.99 ENSDART00000163878
hcn1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr18_+_1837668 0.98 ENSDART00000164210
CABZ01079192.1

chr10_+_22381802 0.93 ENSDART00000112484
nlgn2b
neuroligin 2b
chr16_-_19890303 0.89 ENSDART00000147161
ENSDART00000079159
hdac9b
histone deacetylase 9b
chr3_-_28428198 0.87 ENSDART00000151546
rbfox1
RNA binding fox-1 homolog 1
chr6_-_35472923 0.85 ENSDART00000185907
rgs8
regulator of G protein signaling 8
chr20_+_30490682 0.81 ENSDART00000184871
myt1la
myelin transcription factor 1-like, a
chr14_-_36378494 0.79 ENSDART00000058503
gpm6aa
glycoprotein M6Aa
chr16_-_12953739 0.75 ENSDART00000103894
cacng8b
calcium channel, voltage-dependent, gamma subunit 8b
chr11_+_38280454 0.73 ENSDART00000171496
CDK18
si:dkey-166c18.1
chr2_-_28671139 0.70 ENSDART00000165272
ENSDART00000164657
dhcr7
7-dehydrocholesterol reductase
chr1_+_37752171 0.70 ENSDART00000183247
ENSDART00000189756
ENSDART00000139448
GALNTL6
si:ch211-15e22.3
chr2_+_35421285 0.69 ENSDART00000143787
tnr
tenascin R (restrictin, janusin)
chr24_+_36452927 0.68 ENSDART00000168181
zgc:114120
zgc:114120
chr20_+_23185530 0.64 ENSDART00000142346
lrrc66
leucine rich repeat containing 66
chr19_-_38830582 0.61 ENSDART00000189966
ENSDART00000183055
adgrb2
adhesion G protein-coupled receptor B2
chr23_+_28582865 0.61 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr10_+_29199172 0.60 ENSDART00000148828
picalma
phosphatidylinositol binding clathrin assembly protein a
chr9_+_11532025 0.57 ENSDART00000109037
cdk5r2b
cyclin-dependent kinase 5, regulatory subunit 2b (p39)
chr7_+_30787903 0.56 ENSDART00000174000
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr23_+_26946744 0.55 ENSDART00000115141
cacnb3b
calcium channel, voltage-dependent, beta 3b
chr8_-_43997538 0.55 ENSDART00000186449
rimbp2
RIMS binding protein 2
chr23_-_19230627 0.54 ENSDART00000007122
guca1b
guanylate cyclase activator 1B
chr16_-_13613475 0.54 ENSDART00000139102
dbpb
D site albumin promoter binding protein b
chr21_-_37790727 0.54 ENSDART00000162907
gabrb4
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr18_-_1185772 0.52 ENSDART00000143245
nptnb
neuroplastin b
chr11_+_13224281 0.52 ENSDART00000102557
ENSDART00000178706
abcb11b
ATP-binding cassette, sub-family B (MDR/TAP), member 11b
chr20_+_4060839 0.51 ENSDART00000178565
TRIM67
tripartite motif containing 67
chr4_+_12612723 0.51 ENSDART00000133767
lmo3
LIM domain only 3
chr8_-_23780334 0.50 ENSDART00000145179
ENSDART00000145894
zgc:195245
zgc:195245
chr20_-_9462433 0.50 ENSDART00000152674
ENSDART00000040557
zgc:101840
zgc:101840
chr6_-_50203682 0.50 ENSDART00000083999
ENSDART00000143050
raly
RALY heterogeneous nuclear ribonucleoprotein
chr12_-_19007834 0.50 ENSDART00000153248
chadlb
chondroadherin-like b
chr7_-_69298271 0.50 ENSDART00000122935
phlpp2
PH domain and leucine rich repeat protein phosphatase 2
chr21_+_11244068 0.49 ENSDART00000163432
arid6
AT-rich interaction domain 6
chr19_-_44955710 0.49 ENSDART00000165246
CSMD3 (1 of many)
si:ch211-233f16.1
chr21_+_6751405 0.48 ENSDART00000037265
ENSDART00000146371
olfm1b
olfactomedin 1b
chr10_-_34871737 0.48 ENSDART00000138755
dclk1a
doublecortin-like kinase 1a
chr23_-_20051369 0.47 ENSDART00000049836
bgnb
biglycan b
chr24_-_17023392 0.47 ENSDART00000106058
ptgdsb.2
prostaglandin D2 synthase b, tandem duplicate 2
chr15_-_42736433 0.46 ENSDART00000154379
si:ch211-181d7.1
si:ch211-181d7.1
chr14_+_25817628 0.46 ENSDART00000047680
glra1
glycine receptor, alpha 1
chr16_+_31804590 0.45 ENSDART00000167321
wnt4b
wingless-type MMTV integration site family, member 4b
chr14_-_17622080 0.45 ENSDART00000112149
si:ch211-159i8.4
si:ch211-159i8.4
chr1_-_44701313 0.43 ENSDART00000193926
si:dkey-28b4.8
si:dkey-28b4.8
chr24_+_35881124 0.42 ENSDART00000143015
klhl14
kelch-like family member 14
chr17_+_44780166 0.40 ENSDART00000156260
tmem63c
transmembrane protein 63C
chr10_+_3049636 0.40 ENSDART00000081794
ENSDART00000183167
ENSDART00000191634
ENSDART00000183514
rasgrf2a
Ras protein-specific guanine nucleotide-releasing factor 2a
chr22_+_20427170 0.38 ENSDART00000136744
foxq2
forkhead box Q2
chr21_-_15046065 0.38 ENSDART00000178507
mmp17a
matrix metallopeptidase 17a
chr2_-_54946834 0.38 ENSDART00000192280
CABZ01086574.1

chr8_-_5847533 0.37 ENSDART00000192489
CABZ01102147.1

chr3_+_22059066 0.37 ENSDART00000155739
kansl1b
KAT8 regulatory NSL complex subunit 1b
chr9_-_32730487 0.37 ENSDART00000147795
olig1
oligodendrocyte transcription factor 1
chr17_-_20717845 0.36 ENSDART00000150037
ank3b
ankyrin 3b
chr22_-_7129631 0.36 ENSDART00000171359
asic1b
acid-sensing (proton-gated) ion channel 1b
chr20_-_32270866 0.36 ENSDART00000153140
armc2
armadillo repeat containing 2
chr21_-_43949208 0.35 ENSDART00000150983
camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr4_+_22343093 0.35 ENSDART00000023588
guca1a
guanylate cyclase activator 1A
chr21_+_6751760 0.35 ENSDART00000135914
olfm1b
olfactomedin 1b
chr18_-_37007294 0.33 ENSDART00000088309
map3k10
mitogen-activated protein kinase kinase kinase 10
chr17_-_29192987 0.33 ENSDART00000164302
sptbn5
spectrin, beta, non-erythrocytic 5
chr12_-_6818676 0.33 ENSDART00000106391
pcdh15b
protocadherin-related 15b
chr2_+_21229909 0.33 ENSDART00000046127
vipr1a
vasoactive intestinal peptide receptor 1a
chr4_+_3980247 0.32 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr6_-_6487876 0.31 ENSDART00000137642
cep170ab
centrosomal protein 170Ab
chr25_-_27621268 0.31 ENSDART00000146205
ENSDART00000073511
hyal6
hyaluronoglucosaminidase 6
chr15_-_33172246 0.31 ENSDART00000158666
nbeab
neurobeachin b
chr13_+_38814521 0.31 ENSDART00000110976
col19a1
collagen, type XIX, alpha 1
chr18_-_37007061 0.31 ENSDART00000136432
map3k10
mitogen-activated protein kinase kinase kinase 10
chr14_-_7207961 0.30 ENSDART00000167994
ENSDART00000166532
stox2b
storkhead box 2b
chr18_-_43884044 0.30 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr16_+_45424907 0.29 ENSDART00000134471
phf1
PHD finger protein 1
chr1_-_47071979 0.28 ENSDART00000160817
itsn1
intersectin 1 (SH3 domain protein)
chr4_-_17629444 0.28 ENSDART00000108814
nrip2
nuclear receptor interacting protein 2
chr14_-_33821515 0.27 ENSDART00000173218
vimr2
vimentin-related 2
chr17_+_33311784 0.27 ENSDART00000156229
si:ch211-132f19.7
si:ch211-132f19.7
chr23_-_7799184 0.27 ENSDART00000190946
ENSDART00000165427
myt1b
myelin transcription factor 1b
chr16_+_39159752 0.25 ENSDART00000122081
sybu
syntabulin (syntaxin-interacting)
chr18_+_41232719 0.24 ENSDART00000138552
ENSDART00000145863
trip12
thyroid hormone receptor interactor 12
chr12_+_20412564 0.24 ENSDART00000186783
arhgap17a
Rho GTPase activating protein 17a
chr2_-_15324837 0.23 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr9_+_1313418 0.23 ENSDART00000191361
casp8l2
caspase 8, apoptosis-related cysteine peptidase, like 2
chr18_-_2433011 0.22 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr23_+_36130883 0.22 ENSDART00000103132
hoxc4a
homeobox C4a
chr6_+_24398907 0.21 ENSDART00000167482
tgfbr3
transforming growth factor, beta receptor III
chr4_-_15420452 0.20 ENSDART00000016230
plxna4
plexin A4
chr11_-_42554290 0.20 ENSDART00000130573
atp6ap1la
ATPase H+ transporting accessory protein 1 like a
chr13_+_38817871 0.18 ENSDART00000187708
col19a1
collagen, type XIX, alpha 1
chr21_+_30355767 0.18 ENSDART00000189948
CR749164.1

chr18_-_19095141 0.17 ENSDART00000090962
ENSDART00000090922
dennd4a
DENN/MADD domain containing 4A
chr25_+_11456696 0.17 ENSDART00000171408
AGBL1
si:ch73-141f14.1
chr4_+_41311345 0.17 ENSDART00000151905
si:dkey-16p19.8
si:dkey-16p19.8
chr9_+_11034314 0.16 ENSDART00000032695
asic4a
acid-sensing (proton-gated) ion channel family member 4a
chr19_-_32641725 0.15 ENSDART00000165006
ENSDART00000188185
hpca
hippocalcin
chr3_+_17537352 0.15 ENSDART00000104549
hcrt
hypocretin (orexin) neuropeptide precursor
chr6_+_9289802 0.15 ENSDART00000188650
kalrnb
kalirin RhoGEF kinase b
chr18_+_50461981 0.15 ENSDART00000158761
CU896640.1

chr21_-_5856050 0.15 ENSDART00000115367
CABZ01071020.1

chr8_-_21142550 0.14 ENSDART00000143192
ENSDART00000186820
ENSDART00000135938
cpt2
carnitine palmitoyltransferase 2
chr1_+_57311901 0.14 ENSDART00000149397
mycbpap
mycbp associated protein
chr2_-_32826108 0.13 ENSDART00000098834
prpf4ba
pre-mRNA processing factor 4Ba
chr3_+_17346502 0.13 ENSDART00000187786
ENSDART00000131584
si:ch211-210g13.5
si:ch211-210g13.5
chr4_+_49322310 0.13 ENSDART00000184154
ENSDART00000167162
BX942819.1

chr5_-_51619742 0.13 ENSDART00000188537
otpb
orthopedia homeobox b
chr25_-_3470910 0.13 ENSDART00000029067
ENSDART00000186737
hbp1
HMG-box transcription factor 1
chr23_+_30835589 0.13 ENSDART00000154145
npbwr2a
neuropeptides B/W receptor 2a
chr4_-_75681004 0.12 ENSDART00000186296
si:dkey-71l4.5
si:dkey-71l4.5
chr16_-_37415797 0.12 ENSDART00000188823
si:ch211-208k15.1
si:ch211-208k15.1
chrM_+_9052 0.12 ENSDART00000093612
mt-atp6
ATP synthase 6, mitochondrial
chr2_-_23004286 0.12 ENSDART00000134664
ENSDART00000110373
ENSDART00000185833
ENSDART00000187235
znf414
mllt1b
zinc finger protein 414
MLLT1, super elongation complex subunit b
chr5_+_19343880 0.11 ENSDART00000148130
acacb
acetyl-CoA carboxylase beta
chr7_-_69647988 0.10 ENSDART00000169943
LO018231.1

chr2_-_17235891 0.10 ENSDART00000144251
artnb
artemin b
chr16_-_21038015 0.10 ENSDART00000059239
snx10b
sorting nexin 10b
chr16_+_45425181 0.09 ENSDART00000168591
phf1
PHD finger protein 1
chr21_-_11655010 0.09 ENSDART00000144370
ENSDART00000139814
ENSDART00000139289
cast
calpastatin
chr11_-_29768054 0.08 ENSDART00000079117
plekha3
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
chr16_-_13623928 0.08 ENSDART00000164344
si:dkeyp-69b9.6
si:dkeyp-69b9.6
chr16_-_30903930 0.08 ENSDART00000143996
dennd3b
DENN/MADD domain containing 3b
chr24_-_25004553 0.08 ENSDART00000080997
ENSDART00000136860
zdhhc20b
zinc finger, DHHC-type containing 20b
chr11_+_18873619 0.08 ENSDART00000176141
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr11_-_40147032 0.07 ENSDART00000052918
si:dkey-264d12.4
si:dkey-264d12.4
chr15_-_9272328 0.06 ENSDART00000172114
calm2a
calmodulin 2a (phosphorylase kinase, delta)
chr4_-_9891874 0.06 ENSDART00000067193
adm2a
adrenomedullin 2a
chr20_-_35578435 0.05 ENSDART00000142444
adgrf6
adhesion G protein-coupled receptor F6
chr16_-_16120941 0.05 ENSDART00000131227
ankib1b
ankyrin repeat and IBR domain containing 1b
chr20_+_37294112 0.05 ENSDART00000076293
ENSDART00000140450
cx23
connexin 23
chr7_-_12464412 0.05 ENSDART00000178723
adamtsl3
ADAMTS-like 3
chr12_+_22580579 0.04 ENSDART00000171725
ENSDART00000192290
capgb
capping protein (actin filament), gelsolin-like b
chr18_+_16426266 0.04 ENSDART00000136626
si:dkey-287h13.1
si:dkey-287h13.1
chr22_+_1092479 0.04 ENSDART00000170119
guca1e
guanylate cyclase activator 1e
chr11_-_34522249 0.04 ENSDART00000158616
pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr22_+_21324398 0.04 ENSDART00000168509
shc2
SHC (Src homology 2 domain containing) transforming protein 2
chr10_+_21867307 0.03 ENSDART00000126629
cbln17
cerebellin 17
chr14_+_23717165 0.03 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr16_-_20312146 0.03 ENSDART00000134980
si:dkeyp-86h10.3
si:dkeyp-86h10.3
chr15_-_755023 0.02 ENSDART00000155594
znf1011
zinc finger protein 1011
chr7_+_30926289 0.02 ENSDART00000173518
si:dkey-1h4.4
si:dkey-1h4.4
chr25_-_18913336 0.01 ENSDART00000171010
parietopsin
parietopsin
chr13_+_31205439 0.01 ENSDART00000132326
ptpn20
protein tyrosine phosphatase, non-receptor type 20
chrM_+_9735 0.01 ENSDART00000093613
mt-co3
cytochrome c oxidase III, mitochondrial
chr9_-_19161982 0.00 ENSDART00000081878
pou1f1
POU class 1 homeobox 1

Network of associatons between targets according to the STRING database.

First level regulatory network of dlx3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.2 0.5 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.5 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.1 1.0 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.1 0.9 GO:0097105 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.2 GO:0060074 synapse maturation(GO:0060074)
0.1 0.4 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.7 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.1 GO:0007414 axonal defasciculation(GO:0007414)
0.0 0.8 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 0.2 GO:1900044 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.2 GO:0042755 eating behavior(GO:0042755)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.6 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.7 GO:0042446 hormone biosynthetic process(GO:0042446)
0.0 1.3 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.6 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.3 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 1.1 GO:0007586 digestion(GO:0007586)
0.0 0.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.9 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.4 GO:0031060 regulation of histone methylation(GO:0031060)
0.0 1.1 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.1 GO:0021767 mammillary body development(GO:0021767)
0.0 0.9 GO:0021761 limbic system development(GO:0021761) hypothalamus development(GO:0021854)
0.0 0.6 GO:0070142 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) synaptic vesicle budding(GO:0070142)
0.0 0.2 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.5 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.6 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.5 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.9 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.4 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.4 GO:0003094 glomerular filtration(GO:0003094)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0060077 inhibitory synapse(GO:0060077)
0.2 1.1 GO:0030891 VCB complex(GO:0030891)
0.1 1.4 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.6 GO:0098833 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.8 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0 1.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0044545 NSL complex(GO:0044545)
0.0 0.8 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.5 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0032420 stereocilium(GO:0032420)
0.0 1.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.5 GO:0015126 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.1 0.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.9 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.4 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.9 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.0 GO:0030552 cAMP binding(GO:0030552)
0.1 0.3 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.5 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.6 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.7 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.0 0.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 1.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0035064 methylated histone binding(GO:0035064)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID EPHB FWD PATHWAY EPHB forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.0 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation