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PRJEB1986: zebrafish developmental stages transcriptome

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Results for drgx_arxb

Z-value: 1.24

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Transcription factors associated with drgx_arxb

Gene Symbol Gene ID Gene Info
ENSDARG00000069329 dorsal root ganglia homeobox
ENSDARG00000101523 aristaless related homeobox b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
drgxdr11_v1_chr13_+_30912938_30912938-0.493.3e-02Click!
arxbdr11_v1_chr21_-_40676224_40676224-0.351.4e-01Click!

Activity profile of drgx_arxb motif

Sorted Z-values of drgx_arxb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_31276842 17.00 ENSDART00000187238
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr19_+_40856534 5.88 ENSDART00000051950
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr21_-_27881752 5.60 ENSDART00000132583
neurexin 2a
chr9_+_34641237 5.45 ENSDART00000133996
short stature homeobox
chr19_+_40856807 5.35 ENSDART00000139083
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr19_+_9174166 5.35 ENSDART00000104637
ENSDART00000150968
si:ch211-81a5.8
chr21_+_7582036 4.93 ENSDART00000135485
ENSDART00000027268
orthopedia homeobox a
chr2_+_37227011 3.86 ENSDART00000126587
ENSDART00000084958
sterile alpha motif domain containing 7
chr13_-_29421331 3.73 ENSDART00000150228
choline O-acetyltransferase a
chr20_-_43775495 3.67 ENSDART00000100610
ENSDART00000149001
ENSDART00000148809
ENSDART00000100608
matrilin 3a
chr14_+_22152060 3.56 ENSDART00000082697
ENSDART00000054982
gamma-aminobutyric acid (GABA) A receptor, alpha 6a
chr12_-_20795867 3.44 ENSDART00000152835
ENSDART00000153424
NME/NM23 nucleoside diphosphate kinase 2a
chr9_-_46701326 3.33 ENSDART00000159971
si:ch73-193i22.1
chr18_+_1703984 3.21 ENSDART00000114010
SLIT and NTRK-like family, member 3a
chr17_-_19345521 3.14 ENSDART00000082085
goosecoid
chr24_-_38384432 3.13 ENSDART00000140739
leucine rich repeat containing 4Bb
chr25_-_13381854 3.11 ENSDART00000164621
ENSDART00000169129
NDRG family member 4
chr25_-_19648154 2.94 ENSDART00000148570
ATPase plasma membrane Ca2+ transporting 1b
chr15_+_45640906 2.92 ENSDART00000149361
ENSDART00000149079
S-antigen; retina and pineal gland (arrestin) b
chr3_-_31079186 2.89 ENSDART00000145636
ENSDART00000140569
elongin B
elongin B
chr6_+_40661703 2.87 ENSDART00000142492
enolase 1b, (alpha)
chr12_-_19091214 2.83 ENSDART00000153225
si:ch73-139e5.4
chr16_-_27749172 2.81 ENSDART00000145198
STEAP family member 4
chr4_+_9669717 2.79 ENSDART00000004604
si:dkey-153k10.9
chr3_-_32337653 2.74 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
chr10_-_26744131 2.69 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fibroblast growth factor 13b
chr4_-_14315855 2.48 ENSDART00000133325
neural EGFL like 2b
chr7_+_66822229 2.43 ENSDART00000112109
lymphatic vessel endothelial hyaluronic receptor 1a
chr6_+_23887314 2.43 ENSDART00000163188
zinc finger protein 648
chr22_+_10698549 2.33 ENSDART00000081228
abhydrolase domain containing 14A
chr10_-_34772211 2.16 ENSDART00000145450
ENSDART00000134307
doublecortin-like kinase 1a
chr19_+_10339538 2.10 ENSDART00000151808
ENSDART00000151235
recoverin 3
chr7_-_28148310 2.03 ENSDART00000044208
LIM domain only 1
chr15_+_19797918 2.01 ENSDART00000113314
si:ch211-229d2.5
chr24_-_7697274 1.97 ENSDART00000186077
synaptotagmin Vb
chr9_-_48407408 1.86 ENSDART00000058248
zgc:172182
chr23_-_12345764 1.86 ENSDART00000133956
phosphatase and actin regulator 3a
chr12_+_23850661 1.81 ENSDART00000152921
supervillin a
chr1_+_53954230 1.79 ENSDART00000037729
ENSDART00000159900
centriole, cilia and spindle-associated protein a
chr17_+_18117029 1.77 ENSDART00000154646
ENSDART00000179739
B cell CLL/lymphoma 11Ba
chr20_-_30920356 1.71 ENSDART00000022951
kinesin family member 25
chr14_+_19258702 1.69 ENSDART00000187087
ENSDART00000005738
SLIT and NTRK-like family, member 2
chr6_+_40354424 1.69 ENSDART00000047416
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr12_+_42436920 1.67 ENSDART00000177303
early B cell factor 3a
chr5_-_58840971 1.66 ENSDART00000050932
transmembrane protein 136b
chr5_+_51079504 1.61 ENSDART00000097466
family with sequence similarity 169, member Aa
chr21_+_10739846 1.59 ENSDART00000084011
complexin 4a
chr9_+_29643036 1.46 ENSDART00000023210
ENSDART00000175160
tripartite motif containing 13
chr7_+_26629084 1.42 ENSDART00000101044
ENSDART00000173765
heat shock factor binding protein 1a
chr17_-_31483469 1.40 ENSDART00000062907
ENSDART00000061547
leukocyte receptor tyrosine kinase
chr9_-_27649406 1.39 ENSDART00000181270
ENSDART00000187112
syntaxin binding protein 5-like
chr2_+_30916188 1.34 ENSDART00000137012
myomesin 1a (skelemin)
chr1_+_18811679 1.34 ENSDART00000078610
solute carrier family 25, member 51a
chr16_-_22294265 1.31 ENSDART00000124718
aquaporin 10a
chr18_-_26785861 1.30 ENSDART00000098361
neuromedin Ba
chr8_-_21372446 1.30 ENSDART00000061481
ENSDART00000079293
elastase 2 like
chr24_-_38079261 1.27 ENSDART00000105662
C-reactive protein 1
chr12_-_47601845 1.24 ENSDART00000169548
ENSDART00000182889
regulator of G protein signaling 7b
chr21_-_43022048 1.23 ENSDART00000138329
dihydropyrimidinase-like 3
chr9_+_36314867 1.23 ENSDART00000176763
low density lipoprotein receptor-related protein 1Bb
chr2_+_38554260 1.22 ENSDART00000171527
cadherin 24, type 2b
chr20_-_2134620 1.20 ENSDART00000064375
transmembrane protein 244
chr7_+_20344032 1.19 ENSDART00000144948
ENSDART00000138786
plac8 onzin related protein 1
chr6_+_37894220 1.17 ENSDART00000087311
oculocutaneous albinism II
chr5_+_11407504 1.14 ENSDART00000186723
ENSDART00000018047
zgc:112294
chr5_-_69180587 1.14 ENSDART00000156681
ENSDART00000160753
zgc:171967
chr8_-_7391721 1.14 ENSDART00000149836
LHFPL tetraspan subfamily member 4b
chr10_+_29698467 1.05 ENSDART00000163402
discs, large homolog 2 (Drosophila)
chr21_-_10446405 1.03 ENSDART00000167948
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr21_+_19008168 1.02 ENSDART00000136196
ENSDART00000128381
ENSDART00000176624
neurofilament, light polypeptide a
chr1_+_25801648 1.02 ENSDART00000129471
guanylate cyclase 1 soluble subunit beta 1
chr18_-_8030073 1.01 ENSDART00000151490
SH3 and multiple ankyrin repeat domains 3a
chr11_-_37425407 0.99 ENSDART00000160911
ELKS/RAB6-interacting/CAST family member 2
chr5_-_69180227 0.96 ENSDART00000154816
zgc:171967
chr21_-_20733615 0.95 ENSDART00000145544
si:ch211-22d5.2
chr2_-_5505094 0.94 ENSDART00000145035
S-antigen; retina and pineal gland (arrestin) a
chr3_+_46628885 0.92 ENSDART00000006602
phosphodiesterase 4A, cAMP-specific
chr17_+_30545895 0.90 ENSDART00000076739
NHS-like 1a
chr12_+_42436328 0.89 ENSDART00000167324
early B cell factor 3a
chr20_+_41664350 0.85 ENSDART00000186247
family with sequence similarity 184, member A
chr18_+_38321039 0.85 ENSDART00000132534
ENSDART00000111260
ENSDART00000192806
ALX homeobox 4b
chr17_+_46387086 0.85 ENSDART00000157079
si:dkey-206p8.1
chr6_+_8315050 0.83 ENSDART00000189987
glutaryl-CoA dehydrogenase a
chr4_+_2267641 0.83 ENSDART00000165503
si:ch73-89b15.3
chr13_+_18331509 0.83 ENSDART00000181918
zgc:110319
chr12_+_17504559 0.79 ENSDART00000020628
cytohesin 3a
chr3_-_25268751 0.76 ENSDART00000139423
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase a
chr2_-_48153945 0.76 ENSDART00000146553
phosphofructokinase, platelet b
chr7_+_20344222 0.74 ENSDART00000141186
ENSDART00000139274
plac8 onzin related protein 1
chr17_-_45254585 0.74 ENSDART00000185507
ENSDART00000172080
tau tubulin kinase 2a
chr4_-_28158335 0.72 ENSDART00000134605
GRAM domain containing 4a
chr16_-_27640995 0.72 ENSDART00000019658
NAC alpha domain containing
chr3_-_13921173 0.69 ENSDART00000159177
ENSDART00000165174
si:dkey-61n16.5
chr21_-_17482465 0.66 ENSDART00000004548
BarH-like homeobox 1b
chr10_-_33621739 0.65 ENSDART00000142655
ENSDART00000128049
hormonally up-regulated Neu-associated kinase
chr24_+_25069609 0.65 ENSDART00000115165
APC membrane recruitment protein 2
chr2_+_49417900 0.63 ENSDART00000122742
ENSDART00000160783
RAR-related orphan receptor C b
chr3_+_52753416 0.61 ENSDART00000171185
GEM interacting protein
chr22_-_32507966 0.59 ENSDART00000104693
poly(rC) binding protein 4
chr17_-_14726824 0.58 ENSDART00000162947
si:ch73-305o9.3
chr1_-_18811517 0.58 ENSDART00000142026
si:dkey-167i21.2
chr12_+_10631266 0.57 ENSDART00000161455
colony stimulating factor 3 (granulocyte) a
chr9_-_51436377 0.56 ENSDART00000006612
T-box, brain, 1b
chr22_+_17784414 0.55 ENSDART00000188189
ENSDART00000145260
transmembrane 6 superfamily member 2
chr15_-_21702317 0.55 ENSDART00000155824
si:dkey-40g16.6
chr13_-_49444636 0.54 ENSDART00000136991
interferon regulatory factor 2 binding protein 2a
chr11_+_36409457 0.53 ENSDART00000077641
cytochrome b561 family, member D1
chr18_+_33171765 0.53 ENSDART00000064153
si:ch73-125k17.2
chr5_+_45138934 0.52 ENSDART00000041412
ENSDART00000136002
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr8_-_18203274 0.51 ENSDART00000134078
ENSDART00000180235
ENSDART00000080006
ENSDART00000125418
ENSDART00000142114
ELOVL fatty acid elongase 8b
chr13_+_12761707 0.49 ENSDART00000015127
zgc:100846
chr10_-_5581487 0.47 ENSDART00000141943
spleen tyrosine kinase
chr2_+_20605186 0.47 ENSDART00000128505
olfactomedin-like 2Bb
chr1_-_49250490 0.46 ENSDART00000150386
si:ch73-6k14.2
chr10_+_23537576 0.46 ENSDART00000130515

chr7_+_47243564 0.45 ENSDART00000098942
ENSDART00000162237
zinc finger protein 507
chr20_+_31287356 0.43 ENSDART00000007688
solute carrier family 22 (organic cation/carnitine transporter), member 16
chr7_-_11638126 0.43 ENSDART00000125827
si:dkey-15b23.3
chr3_+_3610140 0.39 ENSDART00000104977
protein interacting with prkca 1
chr3_+_32594357 0.37 ENSDART00000151639
unc-119 lipid binding chaperone B homolog 2
chr2_-_20890429 0.36 ENSDART00000149989
phosducin a
chr5_+_34407763 0.36 ENSDART00000188849
ENSDART00000145127
laminin, gamma 3
chr3_+_29445473 0.35 ENSDART00000020381
GRB2-related adaptor protein 2a
chr12_-_32013125 0.35 ENSDART00000153355
glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb
chr23_+_28770225 0.34 ENSDART00000132179
ENSDART00000142273
mannan-binding lectin serine peptidase 2
chr14_-_17068712 0.34 ENSDART00000170277
paired-like homeobox 2bb
chr5_-_18897482 0.34 ENSDART00000010101
ENSDART00000099434
acetoacetyl-CoA synthetase
chr6_+_49081141 0.32 ENSDART00000131080
ENSDART00000050000
thyroid stimulating hormone, beta subunit, a
chr12_+_20412564 0.32 ENSDART00000186783
Rho GTPase activating protein 17a
chr13_-_50002852 0.32 ENSDART00000099439
lysosomal trafficking regulator
chr6_+_6924637 0.32 ENSDART00000065551
ENSDART00000151393
sterile alpha motif and leucine zipper containing kinase AZK
chr5_+_45139196 0.31 ENSDART00000113738
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr21_+_9997418 0.30 ENSDART00000181454
ENSDART00000171579
hect domain and RLD 7
chr20_+_22130284 0.29 ENSDART00000025575
clock circadian regulator a
chr22_-_15693085 0.28 ENSDART00000141861
si:ch1073-396h14.1
chr5_-_68074592 0.24 ENSDART00000165052
ENSDART00000018792
sperm associated antigen 7
chr2_+_20604775 0.24 ENSDART00000131501
olfactomedin-like 2Bb
chr22_+_17433968 0.24 ENSDART00000139523
RAB GTPase activating protein 1-like
chr10_-_32920690 0.22 ENSDART00000136245
cut-like homeobox 1a
chr16_+_28727383 0.21 ENSDART00000149753
DC-STAMP domain containing 2
chr10_-_1725699 0.20 ENSDART00000183555
galactose-3-O-sulfotransferase 1b
chr5_+_42400777 0.16 ENSDART00000183114

chr16_+_23984755 0.15 ENSDART00000145328
apolipoprotein C-II
chr7_+_20147202 0.14 ENSDART00000011398
si:ch73-335l21.1
chr21_+_21817975 0.14 ENSDART00000151292
ENSDART00000166704
sialidase 3 (membrane sialidase), tandem duplicate 5
chr8_+_35212233 0.13 ENSDART00000111021
si:dkeyp-14d3.1
chr23_-_1658980 0.12 ENSDART00000186227

chr1_-_23110740 0.12 ENSDART00000171848
ENSDART00000086797
ENSDART00000189344
ENSDART00000190858
adhesion G protein-coupled receptor L3.1
chr8_-_43834442 0.12 ENSDART00000191927
adhesion G protein-coupled receptor D1
chr6_+_58698475 0.11 ENSDART00000056138
immunoglobulin superfamily, member 8
chr7_-_52334840 0.09 ENSDART00000174173

chr2_-_42071558 0.08 ENSDART00000142792
centrosome and spindle pole associated protein 1b
chr17_-_39772999 0.07 ENSDART00000155727
Pim proto-oncogene, serine/threonine kinase, related 60
chr25_+_33002963 0.06 ENSDART00000187366

chr5_+_6672870 0.05 ENSDART00000126598
paxillin a
chr4_+_5835393 0.05 ENSDART00000055414
peroxisomal biogenesis factor 26
chr5_+_40299568 0.03 ENSDART00000142157
ADP-ribosylation factor-like 15a
chr11_-_29816429 0.01 ENSDART00000069132
cytochrome b-245, beta polypeptide (chronic granulomatous disease)
chr17_+_28102487 0.00 ENSDART00000131638
ENSDART00000076265
zgc:91908

Network of associatons between targets according to the STRING database.

First level regulatory network of drgx_arxb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.8 4.9 GO:0051703 mammillary body development(GO:0021767) social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.7 2.8 GO:0015677 copper ion import(GO:0015677)
0.4 2.9 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.3 17.0 GO:0003009 skeletal muscle contraction(GO:0003009)
0.3 3.9 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.3 0.8 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.3 1.8 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.3 1.0 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.2 3.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 3.4 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.2 1.4 GO:0070285 pigment cell development(GO:0070285)
0.2 2.7 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 2.1 GO:0036368 cone photoresponse recovery(GO:0036368)
0.2 3.1 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.2 0.7 GO:0034164 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.2 2.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 1.9 GO:0061333 renal tubule morphogenesis(GO:0061333) nephron tubule morphogenesis(GO:0072078) nephron epithelium morphogenesis(GO:0072088)
0.2 3.6 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.2 2.7 GO:0006825 copper ion transport(GO:0006825)
0.2 0.5 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.2 0.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 1.0 GO:2000463 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 0.4 GO:0015695 organic cation transport(GO:0015695)
0.1 0.8 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 6.9 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 1.2 GO:0042438 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.1 1.4 GO:0034605 cellular response to heat(GO:0034605)
0.1 1.0 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.1 3.3 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 0.6 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 0.8 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 1.6 GO:0046887 positive regulation of hormone secretion(GO:0046887)
0.1 0.8 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 1.2 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 1.0 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.1 0.6 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.1 0.4 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.1 6.0 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 1.7 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.5 GO:0036268 swimming(GO:0036268)
0.1 0.8 GO:0061620 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 3.5 GO:0030282 bone mineralization(GO:0030282)
0.1 1.8 GO:0051014 actin filament severing(GO:0051014)
0.1 1.4 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 0.8 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.4 GO:0071632 optomotor response(GO:0071632) caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 2.4 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.6 GO:0007398 ectoderm development(GO:0007398)
0.0 0.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.6 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.3 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 1.4 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 1.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.5 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 2.9 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.0 0.1 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 1.1 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.3 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 1.1 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 1.3 GO:0006936 muscle contraction(GO:0006936)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 11.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.4 17.0 GO:0005861 troponin complex(GO:0005861)
0.4 2.4 GO:0030891 VCB complex(GO:0030891)
0.4 2.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 6.9 GO:0043195 terminal bouton(GO:0043195)
0.2 2.0 GO:0031045 dense core granule(GO:0031045)
0.1 3.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 0.7 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 3.6 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 3.7 GO:0035869 ciliary transition zone(GO:0035869)
0.1 0.4 GO:0098842 postsynaptic early endosome(GO:0098842)
0.1 0.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 3.9 GO:0030426 growth cone(GO:0030426)
0.1 2.7 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 1.3 GO:0031430 M band(GO:0031430)
0.1 0.3 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 1.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.0 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.8 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.4 GO:0031201 SNARE complex(GO:0031201)
0.0 0.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.2 GO:0016342 catenin complex(GO:0016342)
0.0 1.7 GO:0005871 kinesin complex(GO:0005871)
0.0 1.0 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.0 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 4.7 GO:0043235 receptor complex(GO:0043235)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.5 2.7 GO:0016531 copper chaperone activity(GO:0016531)
0.5 11.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.4 2.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 1.3 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.3 3.7 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.3 3.6 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.2 0.8 GO:0071253 connexin binding(GO:0071253)
0.2 0.8 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.2 1.3 GO:0031705 bombesin receptor binding(GO:0031705)
0.2 3.3 GO:0015026 coreceptor activity(GO:0015026)
0.2 2.9 GO:0005080 protein kinase C binding(GO:0005080)
0.1 1.0 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.8 GO:0004104 cholinesterase activity(GO:0004104)
0.1 1.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 3.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 2.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 2.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 10.3 GO:0019905 syntaxin binding(GO:0019905)
0.1 0.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 2.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.0 GO:0030552 cAMP binding(GO:0030552)
0.1 1.0 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 1.0 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 2.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.5 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 4.5 GO:0042393 histone binding(GO:0042393)
0.0 3.9 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 2.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.0 0.1 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 1.4 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.1 GO:0005158 insulin receptor binding(GO:0005158)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 10.9 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 3.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.8 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 11.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.0 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels