Project

PRJEB1986: zebrafish developmental stages transcriptome

Navigation
Downloads

Results for en1b_en2a+en2b_gbx1_emx1

Z-value: 0.97

Motif logo

logo of logo of logo of logo of

Transcription factors associated with en1b_en2a+en2b_gbx1_emx1

Gene Symbol Gene ID Gene Info
en1b
ENSDARG00000098730 engrailed homeobox 1b
en2a
ENSDARG00000026599 engrailed homeobox 2a
en2b
ENSDARG00000038868 engrailed homeobox 2b
en2a
ENSDARG00000115233 engrailed homeobox 2a
gbx1
ENSDARG00000071418 gastrulation brain homeobox 1
emx1
ENSDARG00000039569 empty spiracles homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
en2adr11_v1_chr7_-_40993456_409934560.853.7e-06Click!
en2bdr11_v1_chr2_+_29976419_299764190.493.2e-02Click!
en1bdr11_v1_chr1_+_7679328_76793280.483.8e-02Click!
gbx1dr11_v1_chr24_+_34113424_341134240.381.1e-01Click!
emx1dr11_v1_chr13_+_15004398_150043980.262.8e-01Click!

Activity profile of en1b_en2a+en2b_gbx1_emx1 motif

Sorted Z-values of en1b_en2a+en2b_gbx1_emx1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_306036 2.65 ENSDART00000103659
msgn1
mesogenin 1
chr8_-_50888806 2.48 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr10_+_16036246 2.42 ENSDART00000141586
ENSDART00000135868
ENSDART00000065037
ENSDART00000124502
lmnb1
lamin B1
chr15_+_1796313 1.96 ENSDART00000126253
fam124b
family with sequence similarity 124B
chr1_+_34696503 1.62 ENSDART00000186106
CR339054.2

chr17_+_8799451 1.58 ENSDART00000189814
ENSDART00000191577
tonsl
tonsoku-like, DNA repair protein
chr2_+_20793982 1.57 ENSDART00000014785
prg4a
proteoglycan 4a
chr19_-_19871211 1.57 ENSDART00000170980
evx1
even-skipped homeobox 1
chr2_+_1714640 1.55 ENSDART00000086761
ENSDART00000111613
adgrl2b.1
adgrl2b.1
adhesion G protein-coupled receptor L2b, tandem duplicate 1
adhesion G protein-coupled receptor L2b, tandem duplicate 1
chr12_-_16941319 1.53 ENSDART00000109968
zgc:174855
zgc:174855
chr4_+_34343524 1.50 ENSDART00000171694
si:ch211-246b8.5
si:ch211-246b8.5
chr25_+_14507567 1.44 ENSDART00000015681
dbx1b
developing brain homeobox 1b
chr1_+_33668236 1.39 ENSDART00000122316
ENSDART00000102184
arl13b
ADP-ribosylation factor-like 13b
chr13_+_22295905 1.37 ENSDART00000180133
ENSDART00000181125
usp54a
ubiquitin specific peptidase 54a
chr16_+_28994709 1.37 ENSDART00000088023
gon4l
gon-4-like (C. elegans)
chr7_-_25895189 1.36 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
cd99l2
CD99 molecule-like 2
chr24_+_19415124 1.32 ENSDART00000186931
sulf1
sulfatase 1
chr5_+_66433287 1.27 ENSDART00000170757
kntc1
kinetochore associated 1
chr13_+_30903816 1.25 ENSDART00000191727
ercc6
excision repair cross-complementation group 6
chr10_-_44560165 1.23 ENSDART00000181217
ENSDART00000076084
npm2b
nucleophosmin/nucleoplasmin, 2b
chr12_-_16636627 1.16 ENSDART00000128811
si:dkey-239j18.3
si:dkey-239j18.3
chr19_+_15521997 1.16 ENSDART00000003164
ppp1r8a
protein phosphatase 1, regulatory subunit 8a
chr5_-_12219572 1.14 ENSDART00000167834
nos1
nitric oxide synthase 1 (neuronal)
chr4_-_8014463 1.14 ENSDART00000036153
ccdc3a
coiled-coil domain containing 3a
chr2_+_4146606 1.14 ENSDART00000171170
mib1
mindbomb E3 ubiquitin protein ligase 1
chr18_-_25568994 1.13 ENSDART00000133029
si:ch211-13k12.2
si:ch211-13k12.2
chr13_-_42400647 1.09 ENSDART00000043069
march5
membrane-associated ring finger (C3HC4) 5
chr10_+_17371356 1.08 ENSDART00000122663
sppl3
signal peptide peptidase 3
chr2_+_56213694 1.08 ENSDART00000162582
upf1
upf1 regulator of nonsense transcripts homolog (yeast)
chr10_-_35257458 1.08 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
prr11
proline rich 11
chr22_-_12746539 1.06 ENSDART00000175374
plcd4a
phospholipase C, delta 4a
chr9_-_20372977 1.05 ENSDART00000113418
igsf3
immunoglobulin superfamily, member 3
chr12_-_16558106 1.03 ENSDART00000109033
si:dkey-269i1.4
si:dkey-269i1.4
chr15_+_34988148 1.03 ENSDART00000076269
ccdc105
coiled-coil domain containing 105
chr2_+_4146299 1.02 ENSDART00000173418
mib1
mindbomb E3 ubiquitin protein ligase 1
chr15_+_23799461 1.02 ENSDART00000154885
si:ch211-167j9.4
si:ch211-167j9.4
chr19_+_1831911 1.02 ENSDART00000166653
ptk2aa
protein tyrosine kinase 2aa
chr20_-_9095105 1.00 ENSDART00000140792
oma1
OMA1 zinc metallopeptidase
chr22_+_4488454 0.99 ENSDART00000170620
ctxn1
cortexin 1
chr6_-_43283122 0.99 ENSDART00000186022
frmd4ba
FERM domain containing 4Ba
chr12_-_35830625 0.98 ENSDART00000180028
CU459056.1

chr2_-_55298075 0.97 ENSDART00000186404
ENSDART00000149062
rab8a
RAB8A, member RAS oncogene family
chr3_-_12930217 0.96 ENSDART00000166322
pdgfab
platelet-derived growth factor alpha polypeptide b
chr16_-_22930925 0.93 ENSDART00000133819
si:dkey-246i14.3
si:dkey-246i14.3
chr25_+_35891342 0.92 ENSDART00000147093
lsm14aa
LSM14A mRNA processing body assembly factor a
chr13_+_27232848 0.89 ENSDART00000138043
rin2
Ras and Rab interactor 2
chr5_+_68807170 0.89 ENSDART00000017849
her7
hairy and enhancer of split related-7
chr3_-_23643751 0.88 ENSDART00000078425
ENSDART00000140264
eve1
even-skipped-like1
chr20_-_23426339 0.88 ENSDART00000004625
zar1
zygote arrest 1
chr4_+_9400012 0.88 ENSDART00000191960
tmtc1
transmembrane and tetratricopeptide repeat containing 1
chr21_-_31013817 0.87 ENSDART00000065504
ncbp3
nuclear cap binding subunit 3
chr6_+_39232245 0.87 ENSDART00000187351
b4galnt1b
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr24_+_1023839 0.86 ENSDART00000082526
zgc:111976
zgc:111976
chr16_+_54209504 0.86 ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr14_+_45406299 0.86 ENSDART00000173142
ENSDART00000112377
map1lc3cl
microtubule-associated protein 1 light chain 3 gamma, like
chr1_-_55248496 0.85 ENSDART00000098615
nanos3
nanos homolog 3
chr8_+_29986265 0.85 ENSDART00000148258
ptch1
patched 1
chr5_-_14326959 0.85 ENSDART00000137355
tet3
tet methylcytosine dioxygenase 3
chr8_+_52515188 0.83 ENSDART00000163668
si:ch1073-392o20.2
si:ch1073-392o20.2
chr21_+_43404945 0.82 ENSDART00000142234
frmd7
FERM domain containing 7
chr3_+_22035863 0.82 ENSDART00000177169
cdc27
cell division cycle 27
chr23_-_17003533 0.82 ENSDART00000080545
dnmt3bb.2
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2
chr15_-_16177603 0.82 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr9_+_38372216 0.81 ENSDART00000141895
plcd4b
phospholipase C, delta 4b
chr7_-_51368681 0.80 ENSDART00000146385
arhgap36
Rho GTPase activating protein 36
chr14_-_30387894 0.77 ENSDART00000176136
slc7a2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr3_-_16719244 0.76 ENSDART00000055859
pold1
polymerase (DNA directed), delta 1, catalytic subunit
chr24_-_34680956 0.76 ENSDART00000171009
ctnna1
catenin (cadherin-associated protein), alpha 1
chr13_-_35808904 0.76 ENSDART00000171667
map3k4
mitogen-activated protein kinase kinase kinase 4
chr4_-_9891874 0.75 ENSDART00000067193
adm2a
adrenomedullin 2a
chr4_+_77943184 0.75 ENSDART00000159094
pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr9_+_25568839 0.74 ENSDART00000177342
zeb2a
zinc finger E-box binding homeobox 2a
chr2_+_26288301 0.74 ENSDART00000017668
ptbp1a
polypyrimidine tract binding protein 1a
chr18_-_20458840 0.73 ENSDART00000177125
kif23
kinesin family member 23
chr17_+_8799661 0.73 ENSDART00000105326
tonsl
tonsoku-like, DNA repair protein
chr11_+_33818179 0.72 ENSDART00000109418
spoplb
speckle-type POZ protein-like b
chr8_-_52562672 0.72 ENSDART00000159333
ENSDART00000159974
si:ch73-199g24.2
si:ch73-199g24.2
chr12_-_48168135 0.72 ENSDART00000186624
pald1a
phosphatase domain containing, paladin 1a
chr5_+_59392183 0.71 ENSDART00000082983
ENSDART00000180882
clip2
CAP-GLY domain containing linker protein 2
chr12_-_16694092 0.71 ENSDART00000047916
ctslb
cathepsin Lb
chr23_-_18130264 0.71 ENSDART00000016976
nucks1b
nuclear casein kinase and cyclin-dependent kinase substrate 1b
chr9_-_35633827 0.70 ENSDART00000077745
zp2l1
zona pellucida glycoprotein 2, like 1
chr23_+_44374041 0.70 ENSDART00000136056
ephb4b
eph receptor B4b
chr3_-_15210491 0.69 ENSDART00000037906
hirip3
HIRA interacting protein 3
chr21_+_26390549 0.69 ENSDART00000185643
tmsb
thymosin, beta
chr12_-_16877136 0.68 ENSDART00000152593
si:dkey-269i1.4
si:dkey-269i1.4
chr18_+_9362455 0.68 ENSDART00000187025
sema3ab
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr23_-_1017605 0.66 ENSDART00000138290
cdh26.1
cadherin 26, tandem duplicate 1
chr25_+_16116740 0.65 ENSDART00000139778
far1
fatty acyl CoA reductase 1
chr7_+_15872357 0.65 ENSDART00000165757
pax6b
paired box 6b
chr8_+_48484455 0.65 ENSDART00000122737
PRDM16
si:ch211-263k4.2
chr2_+_11685742 0.65 ENSDART00000138562
greb1l
growth regulation by estrogen in breast cancer-like
chr5_-_68795063 0.64 ENSDART00000016307
her1
hairy-related 1
chr6_-_12275836 0.64 ENSDART00000189980
pkp4
plakophilin 4
chr23_+_42254960 0.64 ENSDART00000102980
zcchc11
zinc finger, CCHC domain containing 11
chr3_+_39663987 0.64 ENSDART00000184614
ENSDART00000184573
ENSDART00000183127
epn2
epsin 2
chr11_-_35171768 0.64 ENSDART00000192896
traip
TRAF-interacting protein
chr5_-_69004007 0.63 ENSDART00000137443
ank1a
ankyrin 1, erythrocytic a
chr5_-_68779747 0.63 ENSDART00000192636
ENSDART00000188039
mepce
methylphosphate capping enzyme
chr12_-_18393408 0.62 ENSDART00000159674
tom1l2
target of myb1 like 2 membrane trafficking protein
chr5_+_19933356 0.62 ENSDART00000088819
ankrd13a
ankyrin repeat domain 13A
chr17_-_20118145 0.62 ENSDART00000149737
ENSDART00000165606
ryr2b
ryanodine receptor 2b (cardiac)
chr3_+_13842554 0.62 ENSDART00000162317
ENSDART00000158068
ilf3b
interleukin enhancer binding factor 3b
chr17_+_16046314 0.61 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr12_-_43664682 0.61 ENSDART00000159423
foxi1
forkhead box i1
chr23_-_31913231 0.61 ENSDART00000146852
ENSDART00000085054
mtfr2
mitochondrial fission regulator 2
chr9_-_21460164 0.60 ENSDART00000133469
zmym2
zinc finger, MYM-type 2
chr11_+_18873113 0.60 ENSDART00000103969
ENSDART00000103968
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr17_+_24821627 0.60 ENSDART00000112389
wdr43
WD repeat domain 43
chr6_+_11850359 0.60 ENSDART00000109552
ENSDART00000188139
ENSDART00000181499
ENSDART00000178269
baz2ba
bromodomain adjacent to zinc finger domain, 2Ba
chr19_+_31585917 0.60 ENSDART00000132182
gmnn
geminin, DNA replication inhibitor
chr4_-_43388943 0.59 ENSDART00000150796
si:dkey-29j8.2
si:dkey-29j8.2
chr18_+_9171778 0.59 ENSDART00000101192
sema3d
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr2_+_6253246 0.59 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr24_-_2450597 0.58 ENSDART00000188080
ENSDART00000093331
rreb1a
ras responsive element binding protein 1a
chr6_+_41191482 0.58 ENSDART00000000877
opn1mw3
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr14_-_15990361 0.58 ENSDART00000168075
trim105
tripartite motif containing 105
chr2_-_56385373 0.58 ENSDART00000169101
cers4b
ceramide synthase 4b
chr4_-_56954002 0.58 ENSDART00000160934
si:dkey-269o24.1
si:dkey-269o24.1
chr10_+_35257651 0.57 ENSDART00000028940
styxl1
serine/threonine/tyrosine interacting-like 1
chr13_-_21660203 0.57 ENSDART00000100925
mxtx1
mix-type homeobox gene 1
chr11_+_24703108 0.57 ENSDART00000159173
gpr25
G protein-coupled receptor 25
chr1_+_513986 0.56 ENSDART00000109083
ENSDART00000081945
txnl4b
thioredoxin-like 4B
chr6_-_40922971 0.56 ENSDART00000155363
sfi1
SFI1 centrin binding protein
chr10_+_8680730 0.56 ENSDART00000011987
isl1l
islet1, like
chr24_-_6078222 0.56 ENSDART00000146830
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr7_+_38936132 0.56 ENSDART00000173945
creb3l1
cAMP responsive element binding protein 3-like 1
chr16_+_6021908 0.55 ENSDART00000163786
BX511115.1

chr17_+_12865746 0.55 ENSDART00000157083
ralgapa1
Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr17_+_12813316 0.55 ENSDART00000155629
ralgapa1
Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr12_+_2446837 0.54 ENSDART00000112032
ARHGAP22
si:dkey-191m6.4
chr15_-_47848544 0.54 ENSDART00000098711
eif3k
eukaryotic translation initiation factor 3, subunit K
chr8_+_21353878 0.54 ENSDART00000056420
alas2
aminolevulinate, delta-, synthase 2
chr15_-_590787 0.54 ENSDART00000189367
si:ch73-144d13.5
si:ch73-144d13.5
chr2_+_41526904 0.53 ENSDART00000127520
acvr1l
activin A receptor, type 1 like
chr8_-_15129573 0.53 ENSDART00000142358
bcar3
BCAR3, NSP family adaptor protein
chr11_-_15296805 0.53 ENSDART00000124968
rpn2
ribophorin II
chr19_-_30510259 0.53 ENSDART00000135128
ENSDART00000186169
ENSDART00000182974
ENSDART00000187797
bag6l
BCL2 associated athanogene 6, like
chr22_-_4439311 0.53 ENSDART00000169317
uhrf1
ubiquitin-like with PHD and ring finger domains 1
chr15_+_46313082 0.51 ENSDART00000153830
si:ch1073-190k2.1
si:ch1073-190k2.1
chr4_-_49582108 0.51 ENSDART00000154999
si:dkey-159n16.2
si:dkey-159n16.2
chr10_+_17714866 0.51 ENSDART00000039969
slc20a1b
solute carrier family 20 (phosphate transporter), member 1b
chr8_-_23612462 0.51 ENSDART00000025024
slc38a5b
solute carrier family 38, member 5b
chr23_-_31913069 0.50 ENSDART00000135526
mtfr2
mitochondrial fission regulator 2
chr21_-_15200556 0.50 ENSDART00000141809
sfswap
splicing factor SWAP
chr1_-_7970653 0.50 ENSDART00000188909
si:dkey-79f11.7
si:dkey-79f11.7
chr1_+_21731382 0.50 ENSDART00000054395
pax5
paired box 5
chr4_-_71152937 0.50 ENSDART00000191017
si:dkey-193i10.4
si:dkey-193i10.4
chr3_-_26183699 0.50 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
si:ch211-11k18.4
chr10_+_6884627 0.50 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr23_-_45705525 0.50 ENSDART00000148959
ednrab
endothelin receptor type Ab
chr7_-_59165640 0.49 ENSDART00000170853
haus6
HAUS augmin-like complex, subunit 6
chr1_-_46981134 0.49 ENSDART00000130607
pknox1.2
pbx/knotted 1 homeobox 1.2
chr11_-_25418856 0.49 ENSDART00000013714
gata1a
GATA binding protein 1a
chr19_+_712127 0.49 ENSDART00000093281
ENSDART00000180002
ENSDART00000146050
fhod3a
formin homology 2 domain containing 3a
chr9_+_25776971 0.48 ENSDART00000146011
zeb2a
zinc finger E-box binding homeobox 2a
chr24_-_1151334 0.48 ENSDART00000039700
ENSDART00000177356
itgb1a
integrin, beta 1a
chr4_+_9450415 0.48 ENSDART00000189690
tmtc1
transmembrane and tetratricopeptide repeat containing 1
chr14_-_33945692 0.48 ENSDART00000168546
ENSDART00000189778
zdhhc24
zinc finger, DHHC-type containing 24
chr7_-_19642417 0.47 ENSDART00000160936
si:ch211-212k18.4
si:ch211-212k18.4
chr4_+_9177997 0.47 ENSDART00000057254
ENSDART00000154614
nfyba
nuclear transcription factor Y, beta a
chr15_+_6774994 0.47 ENSDART00000170011
si:ch1073-228b5.2
si:ch1073-228b5.2
chr19_+_12406583 0.47 ENSDART00000013865
ENSDART00000151535
seh1l
SEH1-like (S. cerevisiae)
chr6_+_4229360 0.47 ENSDART00000191347
ENSDART00000130642
FO082877.1

chr17_+_24722646 0.47 ENSDART00000138356
mtfr1l
mitochondrial fission regulator 1-like
chr11_-_6974022 0.46 ENSDART00000172851
COMP
si:ch211-43f4.1
chr21_-_37973819 0.46 ENSDART00000133405
ripply1
ripply transcriptional repressor 1
chr3_+_18807006 0.46 ENSDART00000180091
tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr4_+_40265583 0.46 ENSDART00000151870
si:ch211-246n15.2
si:ch211-246n15.2
chr22_+_2660505 0.46 ENSDART00000135555
ENSDART00000031485
znf1162
zinc finger protein 1162
chr19_+_26681848 0.46 ENSDART00000138322
si:dkey-27c15.3
si:dkey-27c15.3
chr4_+_11723852 0.45 ENSDART00000028820
mkln1
muskelin 1, intracellular mediator containing kelch motifs
chr8_+_7756893 0.45 ENSDART00000191894
fgd1
FYVE, RhoGEF and PH domain containing 1
chr2_-_50272077 0.45 ENSDART00000127623
cul1a
cullin 1a
chr22_-_881725 0.45 ENSDART00000035514
cept1b
choline/ethanolamine phosphotransferase 1b
chr21_+_34088110 0.45 ENSDART00000145123
ENSDART00000029599
ENSDART00000147519
mtmr1b
myotubularin related protein 1b
chr3_-_38918697 0.44 ENSDART00000145630
si:dkey-106c17.2
si:dkey-106c17.2
chr19_-_20430892 0.44 ENSDART00000111409
tbc1d5
TBC1 domain family, member 5
chr4_+_6032640 0.44 ENSDART00000157487
tfec
transcription factor EC
chr5_-_67241633 0.44 ENSDART00000114783
clip1a
CAP-GLY domain containing linker protein 1a
chr15_+_36309070 0.44 ENSDART00000157034
gmnc
geminin coiled-coil domain containing
chr7_+_65813301 0.44 ENSDART00000187449
ENSDART00000179834
ENSDART00000082740
ENSDART00000178627
tead1b
TEA domain family member 1b
chr22_+_5176255 0.43 ENSDART00000092647
cers1
ceramide synthase 1
chr1_-_51719110 0.43 ENSDART00000190574
rnaseh2a
ribonuclease H2, subunit A
chr21_-_23017478 0.42 ENSDART00000024309
rb1
retinoblastoma 1
chr24_+_22485710 0.42 ENSDART00000146058
si:dkey-40h20.1
si:dkey-40h20.1
chr18_+_17725410 0.41 ENSDART00000090608
rspry1
ring finger and SPRY domain containing 1
chr15_-_2497568 0.41 ENSDART00000080398
neu4
sialidase 4
chr18_-_25646286 0.41 ENSDART00000099511
ENSDART00000186890
si:ch211-13k12.2
si:ch211-13k12.2
chr24_-_25004553 0.41 ENSDART00000080997
ENSDART00000136860
zdhhc20b
zinc finger, DHHC-type containing 20b
chr5_+_63302660 0.41 ENSDART00000142131
si:ch73-376l24.2
si:ch73-376l24.2
chr9_+_19529951 0.41 ENSDART00000125416
pknox1.1
pbx/knotted 1 homeobox 1.1
chr10_+_16584382 0.40 ENSDART00000112039
CR790388.1

chr15_-_5178899 0.39 ENSDART00000132148
or126-4
odorant receptor, family E, subfamily 126, member 4
chr23_-_333457 0.39 ENSDART00000114486
uhrf1bp1
UHRF1 binding protein 1
chr16_-_41714988 0.39 ENSDART00000138798
cep85
centrosomal protein 85
chr18_+_24921587 0.39 ENSDART00000191345
rgma
repulsive guidance molecule family member a
chr9_-_32753535 0.39 ENSDART00000060006
olig2
oligodendrocyte lineage transcription factor 2
chr12_-_33817114 0.39 ENSDART00000161265
twnk
twinkle mtDNA helicase
chr8_+_17168114 0.38 ENSDART00000183901
cenph
centromere protein H

Network of associatons between targets according to the STRING database.

First level regulatory network of en1b_en2a+en2b_gbx1_emx1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.8 2.5 GO:0021519 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519)
0.5 1.4 GO:1903441 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.4 1.1 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
0.4 1.1 GO:1901232 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.3 1.0 GO:1900182 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.3 0.9 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.2 1.0 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.2 1.9 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2 1.2 GO:0000012 single strand break repair(GO:0000012)
0.2 0.9 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 1.5 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.2 0.8 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.2 0.7 GO:0060471 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.2 1.3 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.2 1.2 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.2 0.9 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.2 0.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 0.8 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.2 0.8 GO:0032776 DNA methylation on cytosine(GO:0032776) regulation of histone H3-K9 methylation(GO:0051570)
0.2 0.6 GO:0048890 epidermal cell fate specification(GO:0009957) lateral line ganglion development(GO:0048890)
0.1 0.7 GO:0002164 larval development(GO:0002164) larval heart development(GO:0007508)
0.1 1.3 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.6 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 0.5 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.1 0.4 GO:0021742 abducens nucleus development(GO:0021742)
0.1 0.8 GO:1902837 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.1 0.5 GO:0089709 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 2.6 GO:0031297 replication fork processing(GO:0031297)
0.1 1.0 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.5 GO:0030224 monocyte differentiation(GO:0030224)
0.1 1.0 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.2 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.1 0.7 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.1 0.2 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.1 0.3 GO:0046125 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.3 GO:0048785 hatching gland development(GO:0048785)
0.1 0.7 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.5 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.1 1.4 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.1 0.8 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.1 0.7 GO:0090104 pancreatic D cell differentiation(GO:0003311) pancreatic epsilon cell differentiation(GO:0090104)
0.1 2.6 GO:0001757 somite specification(GO:0001757)
0.1 0.4 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 2.2 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.9 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.1 0.5 GO:0097065 anterior head development(GO:0097065)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.3 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.4 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.3 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.1 0.4 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.1 0.1 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.1 0.2 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.1 1.0 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.7 GO:0060118 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.1 0.4 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.2 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 0.7 GO:0001765 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1 0.4 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.1 0.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.8 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 0.5 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.7 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 0.2 GO:1903332 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.1 0.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.3 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.2 GO:1902895 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.1 0.3 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 0.3 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.2 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.1 0.7 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 0.4 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.5 GO:0044030 regulation of DNA methylation(GO:0044030)
0.1 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.3 GO:0006691 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.1 0.3 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 0.2 GO:0014814 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.1 0.5 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1 0.3 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1 0.5 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 0.2 GO:0048569 post-embryonic organ development(GO:0048569)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.4 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.1 GO:0015884 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.0 0.2 GO:0000741 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.0 0.3 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.6 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0052576 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.0 0.2 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 1.5 GO:0000266 mitochondrial fission(GO:0000266)
0.0 1.3 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.7 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.0 1.2 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.8 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.2 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.0 0.1 GO:0007414 axonal defasciculation(GO:0007414)
0.0 0.1 GO:0030858 positive regulation of epithelial cell differentiation(GO:0030858) regulation of endothelial cell differentiation(GO:0045601)
0.0 1.2 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0019323 pentose catabolic process(GO:0019323)
0.0 0.6 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.6 GO:0003181 atrioventricular valve morphogenesis(GO:0003181)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.5 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0 0.1 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.5 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 1.1 GO:0097202 activation of cysteine-type endopeptidase activity(GO:0097202)
0.0 0.1 GO:0045429 regulation of nitric oxide biosynthetic process(GO:0045428) positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
0.0 0.2 GO:0006660 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:0048211 Golgi vesicle docking(GO:0048211)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.2 GO:0060420 regulation of heart growth(GO:0060420)
0.0 1.7 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.0 0.6 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 0.2 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.4 GO:0051382 kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.0 0.3 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.0 0.1 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.0 0.6 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 1.4 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.2 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967) 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.0 0.2 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.9 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.5 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.4 GO:0035459 cargo loading into vesicle(GO:0035459)
0.0 0.5 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.2 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 0.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion(GO:0061400) positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.7 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.1 GO:0072512 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.1 GO:0050748 N-terminal protein palmitoylation(GO:0006500) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.0 0.2 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.7 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.1 GO:0016045 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.0 0.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.1 GO:0036268 swimming(GO:0036268)
0.0 0.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.0 0.0 GO:0097378 interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
0.0 0.1 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.2 GO:0009303 rRNA transcription(GO:0009303) swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 0.4 GO:1901888 regulation of cell junction assembly(GO:1901888)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.3 GO:0045471 response to ethanol(GO:0045471)
0.0 0.1 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.0 0.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0098900 regulation of action potential(GO:0098900)
0.0 0.1 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.5 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.3 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.1 GO:0060847 cell proliferation in dorsal spinal cord(GO:0010456) endothelial cell fate specification(GO:0060847)
0.0 0.0 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:0051443 regulation of ubiquitin-protein transferase activity(GO:0051438) positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0051645 Golgi localization(GO:0051645)
0.0 0.3 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.6 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.1 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.0 0.2 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.4 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.1 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.2 GO:0032418 lysosome localization(GO:0032418)
0.0 0.3 GO:0001736 establishment of planar polarity(GO:0001736) establishment of tissue polarity(GO:0007164)
0.0 1.4 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.0 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.0 0.1 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 0.1 GO:2001271 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0010867 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.7 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.1 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.0 0.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.0 0.0 GO:0015677 copper ion import(GO:0015677)
0.0 0.8 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.1 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.0 GO:1903318 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.0 0.2 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.2 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 1.0 GO:0034249 negative regulation of translation(GO:0017148) negative regulation of cellular amide metabolic process(GO:0034249)
0.0 0.6 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.1 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 0.3 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.3 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.4 GO:0031102 neuron projection regeneration(GO:0031102)
0.0 5.6 GO:0051603 proteolysis involved in cellular protein catabolic process(GO:0051603)
0.0 0.1 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.2 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.2 GO:0010883 regulation of lipid storage(GO:0010883)
0.0 0.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.7 GO:0016331 morphogenesis of embryonic epithelium(GO:0016331)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.3 2.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 0.8 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.5 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.1 0.5 GO:0070724 BMP receptor complex(GO:0070724)
0.1 0.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.5 GO:0071818 BAT3 complex(GO:0071818)
0.1 0.2 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1 0.8 GO:0030669 clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 1.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 0.3 GO:0070209 ASTRA complex(GO:0070209)
0.1 0.2 GO:0072379 ER membrane insertion complex(GO:0072379) TRC complex(GO:0072380)
0.1 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.3 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 0.4 GO:0035060 brahma complex(GO:0035060)
0.1 1.2 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 1.2 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 1.4 GO:0043186 P granule(GO:0043186)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0097189 apoptotic body(GO:0097189)
0.0 0.3 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.3 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 2.2 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 1.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0030904 retromer complex(GO:0030904)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 1.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.5 GO:0000792 heterochromatin(GO:0000792)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.0 0.5 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0030892 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.0 2.1 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.3 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.8 GO:0005795 Golgi stack(GO:0005795)
0.0 0.3 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 3.9 GO:0005764 lysosome(GO:0005764)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 1.7 GO:0016607 nuclear speck(GO:0016607)
0.0 0.7 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 1.3 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0097546 ciliary base(GO:0097546)
0.0 0.1 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.3 GO:0005925 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 0.4 GO:0005657 replication fork(GO:0005657)
0.0 0.1 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0097108 hedgehog family protein binding(GO:0097108)
0.2 2.3 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.2 0.5 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 0.9 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.2 0.9 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 1.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 1.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 1.4 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.6 GO:0009374 biotin binding(GO:0009374)
0.1 1.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.4 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 1.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.3 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.6 GO:0060182 apelin receptor activity(GO:0060182)
0.1 0.8 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.5 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.5 GO:0098634 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.5 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 1.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.4 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.1 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.6 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 1.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 1.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.2 GO:0019777 Atg12 transferase activity(GO:0019777)
0.1 0.5 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.2 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.1 0.8 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 0.5 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.7 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.8 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.2 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 0.4 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.2 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.2 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.6 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 1.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 1.1 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.4 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.4 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0043531 ADP binding(GO:0043531)
0.0 0.1 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.0 1.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.5 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 5.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.0 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.3 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.0 0.5 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.3 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.0 1.5 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.4 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 0.1 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.0 0.5 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.9 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 1.4 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 4.2 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 2.0 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 0.4 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.9 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 1.6 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.1 GO:0015140 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 0.1 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 1.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.1 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.0 1.2 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 1.5 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.0 GO:0060175 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.0 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
0.0 0.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.0 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.5 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 ST GA13 PATHWAY G alpha 13 Pathway
0.1 2.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 3.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.4 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.8 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID P73PATHWAY p73 transcription factor network
0.0 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.4 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 2.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.6 REACTOME BASE EXCISION REPAIR Genes involved in Base Excision Repair
0.1 1.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.0 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 1.2 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.7 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.8 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 2.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.2 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.4 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.4 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.3 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.1 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.3 REACTOME MEIOSIS Genes involved in Meiosis
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity