Project

PRJEB1986: zebrafish developmental stages transcriptome

Navigation
Downloads

Results for eomesa

Z-value: 0.73

Motif logo

logo of

Transcription factors associated with eomesa

Gene Symbol Gene ID Gene Info
eomesa
ENSDARG00000006640 eomesodermin homolog a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
eomesadr11_v1_chr19_-_867071_867071-0.589.3e-03Click!

Activity profile of eomesa motif

Sorted Z-values of eomesa motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_2602445 1.97 ENSDART00000166910
etf1a
eukaryotic translation termination factor 1a
chr2_-_32637592 1.76 ENSDART00000136353
si:dkeyp-73d8.8
si:dkeyp-73d8.8
chr13_-_7031033 1.41 ENSDART00000193211
CABZ01061524.1

chr3_+_59051503 1.22 ENSDART00000160767
rasd4
rasd family member 4
chr20_-_14665002 1.05 ENSDART00000152816
scrn2
secernin 2
chr1_-_40015782 1.05 ENSDART00000157425
ENSDART00000159238
cdk2ap2
cyclin-dependent kinase 2 associated protein 2
chr25_-_13703826 0.92 ENSDART00000163398
pla2g15
phospholipase A2, group XV
chr15_-_21877726 0.90 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
zgc:162608
chr22_+_25274712 0.86 ENSDART00000137341
BX950205.1

chr20_-_40755614 0.84 ENSDART00000061247
cx32.3
connexin 32.3
chr13_-_9318891 0.83 ENSDART00000137364
si:dkey-33c12.3
si:dkey-33c12.3
chr7_-_61845282 0.79 ENSDART00000182586
HTRA3
HtrA serine peptidase 3
chr2_-_13216269 0.79 ENSDART00000149947
bcl2b
BCL2, apoptosis regulator b
chr7_+_21887787 0.77 ENSDART00000162252
pop7
POP7 homolog, ribonuclease P/MRP subunit
chr7_+_23907692 0.76 ENSDART00000045479
syt4
synaptotagmin IV
chr1_-_40016058 0.73 ENSDART00000165373
cdk2ap2
cyclin-dependent kinase 2 associated protein 2
chr2_-_58085444 0.72 ENSDART00000166395
fcer1gl
Fc receptor, IgE, high affinity I, gamma polypeptide like
chr12_-_48960308 0.72 ENSDART00000176247
CABZ01112647.1

chr21_-_27010796 0.72 ENSDART00000065398
ENSDART00000144342
ENSDART00000126542
ppp1r14ba
protein phosphatase 1, regulatory (inhibitor) subunit 14Ba
chr10_-_5847904 0.65 ENSDART00000161096
ankrd55
ankyrin repeat domain 55
chr10_-_26997344 0.62 ENSDART00000146595
zgc:193742
zgc:193742
chr7_-_7845540 0.61 ENSDART00000166280
cxcl8b.1
chemokine (C-X-C motif) ligand 8b, duplicate 1
chr10_-_5847655 0.61 ENSDART00000192773
ankrd55
ankyrin repeat domain 55
chr12_+_5129245 0.55 ENSDART00000169073
pde6c
phosphodiesterase 6C, cGMP-specific, cone, alpha prime
chr19_+_3849378 0.54 ENSDART00000166218
ENSDART00000159228
oscp1a
organic solute carrier partner 1a
chr22_-_6066867 0.51 ENSDART00000142383
si:dkey-19a16.1
si:dkey-19a16.1
chr20_-_46773258 0.50 ENSDART00000060653
si:ch211-57i17.5
si:ch211-57i17.5
chr10_+_26612321 0.49 ENSDART00000134322
fhl1b
four and a half LIM domains 1b
chr6_-_15641686 0.48 ENSDART00000135583
mlpha
melanophilin a
chr2_-_10896745 0.47 ENSDART00000114609
cdcp2
CUB domain containing protein 2
chr3_+_6469754 0.46 ENSDART00000185809
NUP85 (1 of many)
nucleoporin 85
chr24_-_24060632 0.45 ENSDART00000090514
abcc13
ATP-binding cassette, sub-family C (CFTR/MRP), member 13
chr25_+_33939728 0.38 ENSDART00000148537
roraa
RAR-related orphan receptor A, paralog a
chr23_-_31648026 0.37 ENSDART00000133569
sgk1
serum/glucocorticoid regulated kinase 1
chr7_+_27691647 0.37 ENSDART00000079091
cyp2r1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr12_-_28881638 0.36 ENSDART00000148459
ENSDART00000039667
ENSDART00000148668
ENSDART00000136593
ENSDART00000139923
ENSDART00000148912
cbx1b
chromobox homolog 1b (HP1 beta homolog Drosophila)
chr23_-_31647793 0.36 ENSDART00000145621
sgk1
serum/glucocorticoid regulated kinase 1
chr9_-_21238616 0.35 ENSDART00000191840
ENSDART00000189127
cox17
COX17 cytochrome c oxidase copper chaperone
chr11_-_40728380 0.33 ENSDART00000023745
ccdc114
coiled-coil domain containing 114
chr10_-_8956973 0.32 ENSDART00000189564
mocs2
molybdenum cofactor synthesis 2
chr22_+_26263290 0.32 ENSDART00000184840
BX649315.1

chr22_+_19111444 0.31 ENSDART00000109655
fgf22
fibroblast growth factor 22
chr13_+_33703784 0.30 ENSDART00000173361
macrod2
MACRO domain containing 2
chr12_-_25380028 0.29 ENSDART00000142674
zfp36l2
zinc finger protein 36, C3H type-like 2
chr8_-_43158486 0.27 ENSDART00000134801
ccdc92
coiled-coil domain containing 92
chr17_-_33415740 0.26 ENSDART00000135218
ccdc28a
coiled-coil domain containing 28A
chr13_-_280827 0.25 ENSDART00000144819
slc30a6
solute carrier family 30 (zinc transporter), member 6
chr17_+_36588281 0.25 ENSDART00000076115
htr1b
5-hydroxytryptamine (serotonin) receptor 1B
chr7_+_73332486 0.24 ENSDART00000174119
ENSDART00000092051
ENSDART00000192388
CABZ01081780.1

chr22_+_25352530 0.23 ENSDART00000176742
ENSDART00000113186
si:dkey-240e12.6
si:dkey-240e12.6
chr7_-_2090594 0.23 ENSDART00000183166
si:cabz01007802.1
si:cabz01007802.1
chr8_-_22965916 0.22 ENSDART00000143791
emilin3a
elastin microfibril interfacer 3a
chr10_+_40606084 0.21 ENSDART00000133119
si:ch211-238p8.24
si:ch211-238p8.24
chr12_-_10421955 0.21 ENSDART00000052004
zgc:153595
zgc:153595
chr1_-_8966046 0.21 ENSDART00000136198
socs1b
suppressor of cytokine signaling 1b
chr2_+_35240485 0.21 ENSDART00000179804
tnr
tenascin R (restrictin, janusin)
chr21_-_14815952 0.20 ENSDART00000134278
ENSDART00000067004
phpt1
phosphohistidine phosphatase 1
chr5_-_67762434 0.19 ENSDART00000167301
b4galt4
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr9_-_23824290 0.18 ENSDART00000059209
wdfy2
WD repeat and FYVE domain containing 2
chr2_-_57469115 0.18 ENSDART00000192201
pias4b
protein inhibitor of activated STAT, 4b
chr16_+_23947196 0.18 ENSDART00000103190
ENSDART00000132961
ENSDART00000147690
ENSDART00000142168
apoa4b.2
apolipoprotein A-IV b, tandem duplicate 2
chr1_-_55750208 0.18 ENSDART00000142244
dnajb1b
DnaJ (Hsp40) homolog, subfamily B, member 1b
chr1_-_57129179 0.17 ENSDART00000157226
ENSDART00000152469
si:ch73-94k4.2
si:ch73-94k4.2
chr7_+_21275152 0.17 ENSDART00000173612
serpinh2
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr7_-_69983462 0.17 ENSDART00000123380
KCNIP4
potassium voltage-gated channel interacting protein 4
chr12_-_17424162 0.17 ENSDART00000079144
ENSDART00000079138
ptenb
phosphatase and tensin homolog B
chr22_+_25704430 0.17 ENSDART00000143776
si:dkeyp-98a7.3
si:dkeyp-98a7.3
chr1_+_29741843 0.16 ENSDART00000136066
raph1b
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b
chr25_-_17852944 0.16 ENSDART00000155169
si:ch211-176l24.4
si:ch211-176l24.4
chr5_-_16475374 0.16 ENSDART00000134274
ENSDART00000136004
piwil2
piwi-like RNA-mediated gene silencing 2
chr22_-_18544701 0.15 ENSDART00000132156
cirbpb
cold inducible RNA binding protein b
chr1_+_57142509 0.15 ENSDART00000146799
si:ch73-94k4.3
si:ch73-94k4.3
chr11_+_14312260 0.14 ENSDART00000102518
si:ch211-262i1.5
si:ch211-262i1.5
chr22_-_5252005 0.14 ENSDART00000132942
ENSDART00000081801
ncln
nicalin
chr17_-_33416020 0.13 ENSDART00000140149
ccdc28a
coiled-coil domain containing 28A
chr2_-_34555945 0.13 ENSDART00000056671
brinp2
bone morphogenetic protein/retinoic acid inducible neural-specific 2
chr13_-_49586255 0.13 ENSDART00000190813
tomm20a
translocase of outer mitochondrial membrane 20
chr18_-_50921002 0.13 ENSDART00000017053
ENSDART00000008696
cttn
cortactin
chr4_-_77624155 0.12 ENSDART00000099761
si:ch211-250m6.7
si:ch211-250m6.7
chr5_-_45877387 0.12 ENSDART00000183714
ENSDART00000041503
slc4a4a
solute carrier family 4 (sodium bicarbonate cotransporter), member 4a
chr10_-_25217347 0.11 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr13_-_280652 0.11 ENSDART00000193627
slc30a6
solute carrier family 30 (zinc transporter), member 6
chr3_+_16449490 0.10 ENSDART00000141467
kcnj12b
potassium inwardly-rectifying channel, subfamily J, member 12b
chr6_+_54538948 0.09 ENSDART00000149270
tulp1b
tubby like protein 1b
chr5_-_41645058 0.09 ENSDART00000051092
riok2
RIO kinase 2 (yeast)
chr6_+_28877306 0.09 ENSDART00000065137
ENSDART00000123189
ENSDART00000065135
ENSDART00000181512
ENSDART00000130799
tp63
tumor protein p63
chr22_+_25681911 0.09 ENSDART00000113381
si:dkeyp-98a7.3
si:dkeyp-98a7.3
chr22_+_25687525 0.09 ENSDART00000135717
si:dkeyp-98a7.3
si:dkeyp-98a7.3
chr4_+_56833071 0.09 ENSDART00000157504
si:dkeyp-33c10.7
si:dkeyp-33c10.7
chr2_-_9607879 0.08 ENSDART00000056899
txndc12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr22_+_39096911 0.08 ENSDART00000157127
ENSDART00000153841
lmcd1
LIM and cysteine-rich domains 1
chr22_+_25753972 0.08 ENSDART00000188417
AL929192.2

chr5_+_45000597 0.08 ENSDART00000051146
dmrt3a
doublesex and mab-3 related transcription factor 3a
chr18_+_33779440 0.07 ENSDART00000133349
si:dkey-145c18.3
si:dkey-145c18.3
chr1_+_45323400 0.07 ENSDART00000148906
ENSDART00000132366
emp1
epithelial membrane protein 1
chr11_-_4137242 0.07 ENSDART00000184669
BX571768.1

chr10_+_19595009 0.06 ENSDART00000112276
zgc:173837
zgc:173837
chr10_+_23511816 0.06 ENSDART00000127255
zmp:0000000924
zmp:0000000924
chr3_-_31784082 0.06 ENSDART00000134201
kcnh6a
potassium voltage-gated channel, subfamily H (eag-related), member 6a
chr9_+_44721808 0.05 ENSDART00000190578
nckap1
NCK-associated protein 1
chr5_+_13647288 0.05 ENSDART00000099660
ENSDART00000139199
h2afva
H2A histone family, member Va
chr19_-_81851 0.04 ENSDART00000172319
hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr20_-_32007209 0.04 ENSDART00000021575
adgb
androglobin
chr14_+_49231776 0.04 ENSDART00000169096
rmnd5b
required for meiotic nuclear division 5 homolog B
chr10_+_16225870 0.03 ENSDART00000164647
slc12a2
solute carrier family 12 (sodium/potassium/chloride transporter), member 2
chr22_+_25715925 0.03 ENSDART00000150650
si:dkeyp-98a7.7
si:dkeyp-98a7.7
chr5_+_37379825 0.03 ENSDART00000171826
klhl13
kelch-like family member 13
chr11_+_14622379 0.02 ENSDART00000112589
efna2b
ephrin-A2b
chr22_+_25693295 0.02 ENSDART00000123888
ENSDART00000150783
si:dkeyp-98a7.4
si:dkeyp-98a7.3
si:dkeyp-98a7.4
si:dkeyp-98a7.3
chr3_+_37083765 0.02 ENSDART00000125611
retreg3
reticulophagy regulator family member 3
chr3_-_31783737 0.01 ENSDART00000090809
kcnh6a
potassium voltage-gated channel, subfamily H (eag-related), member 6a

Network of associatons between targets according to the STRING database.

First level regulatory network of eomesa

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 0.9 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.1 0.5 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.6 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.4 GO:0071305 cellular response to vitamin D(GO:0071305)
0.1 0.2 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
0.0 0.5 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.3 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 1.3 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.2 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.2 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.0 0.3 GO:0043545 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.7 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.1 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 0.8 GO:0038034 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) response to copper ion(GO:0046688) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0060306 regulation of membrane repolarization(GO:0060306) regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.0 0.8 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.4 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.2 GO:0046849 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) bone remodeling(GO:0046849)
0.0 0.1 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.4 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.0 1.2 GO:0031101 fin regeneration(GO:0031101)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0018444 translation release factor complex(GO:0018444)
0.2 0.7 GO:0032998 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.1 0.9 GO:0042627 chylomicron(GO:0042627)
0.1 0.3 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 0.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 0.7 GO:0019767 immunoglobulin receptor activity(GO:0019763) IgE receptor activity(GO:0019767)
0.2 0.9 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.2 0.9 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.2 0.6 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.1 0.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.3 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.1 0.4 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.8 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.0 0.2 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.9 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 1.2 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0 0.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.5 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0017022 myosin binding(GO:0017022)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.7 PID FOXO PATHWAY FoxO family signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type