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PRJEB1986: zebrafish developmental stages transcriptome

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Results for esrrd+esrrga_esrrb_esrra+esrrgb

Z-value: 2.55

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Transcription factors associated with esrrd+esrrga_esrrb_esrra+esrrgb

Gene Symbol Gene ID Gene Info
esrrga
ENSDARG00000004861 estrogen-related receptor gamma a
esrrd
ENSDARG00000015064 estrogen-related receptor delta
esrrb
ENSDARG00000100847 estrogen-related receptor beta
esrrgb
ENSDARG00000011696 estrogen-related receptor gamma b
esrra
ENSDARG00000069266 estrogen-related receptor alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
esrrbdr11_v1_chr17_-_29902187_299021870.812.3e-05Click!
esrradr11_v1_chr21_+_26612777_266127770.761.8e-04Click!
esrrgbdr11_v1_chr20_-_46808870_468088700.716.3e-04Click!
esrrddr11_v1_chr18_-_48992363_489923630.571.1e-02Click!

Activity profile of esrrd+esrrga_esrrb_esrra+esrrgb motif

Sorted Z-values of esrrd+esrrga_esrrb_esrra+esrrgb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_11385155 13.85 ENSDART00000064214
plac8.1
placenta-specific 8, tandem duplicate 1
chr12_+_34896956 13.41 ENSDART00000055415
prph2a
peripherin 2a (retinal degeneration, slow)
chr9_+_22003942 12.30 ENSDART00000091013
si:dkey-57a22.15
si:dkey-57a22.15
chr7_+_35068036 10.58 ENSDART00000022139
zgc:136461
zgc:136461
chr17_-_12385308 10.02 ENSDART00000080927
snap25b
synaptosomal-associated protein, 25b
chr13_+_50375800 9.95 ENSDART00000099537
cox5b2
cytochrome c oxidase subunit Vb 2
chr15_+_20403903 9.80 ENSDART00000134182
cox7a1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr9_-_44939104 8.62 ENSDART00000192903
vil1
villin 1
chr5_-_37886063 8.38 ENSDART00000131378
ENSDART00000132152
si:ch211-139a5.9
si:ch211-139a5.9
chr16_+_52512025 7.54 ENSDART00000056095
fabp10a
fatty acid binding protein 10a, liver basic
chr8_+_24854600 7.31 ENSDART00000156570
slc6a17
solute carrier family 6 (neutral amino acid transporter), member 17
chr11_+_25472758 7.24 ENSDART00000011178
opn1sw2
opsin 1 (cone pigments), short-wave-sensitive 2
chr5_+_1278092 7.16 ENSDART00000147972
ENSDART00000159783
dnm1a
dynamin 1a
chr6_+_48618512 6.91 ENSDART00000111190
FAM19A3
si:dkey-238f9.1
chr25_+_3326885 6.90 ENSDART00000104866
ldhbb
lactate dehydrogenase Bb
chr23_+_44611864 6.79 ENSDART00000145905
ENSDART00000132361
eno3
enolase 3, (beta, muscle)
chr9_-_48736388 6.41 ENSDART00000022074
dhrs9
dehydrogenase/reductase (SDR family) member 9
chr3_-_21280373 6.26 ENSDART00000003939
syngr1a
synaptogyrin 1a
chr11_+_21076872 6.05 ENSDART00000155521
prelp
proline/arginine-rich end leucine-rich repeat protein
chr11_-_7320211 6.04 ENSDART00000091664
apc2
adenomatosis polyposis coli 2
chr3_-_3209432 5.97 ENSDART00000140635
si:ch211-229i14.2
si:ch211-229i14.2
chr15_+_19797918 5.89 ENSDART00000113314
si:ch211-229d2.5
si:ch211-229d2.5
chr12_-_30841679 5.85 ENSDART00000105594
crygmx
crystallin, gamma MX
chr4_-_1360495 5.70 ENSDART00000164623
ptn
pleiotrophin
chr7_-_48805181 5.37 ENSDART00000015884
mfge8a
milk fat globule-EGF factor 8 protein a
chr14_-_33454595 5.36 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
tmem255a
transmembrane protein 255A
chr3_-_60142530 5.33 ENSDART00000153247
si:ch211-120g10.1
si:ch211-120g10.1
chr20_+_6142433 5.32 ENSDART00000054084
ENSDART00000136986
ttr
transthyretin (prealbumin, amyloidosis type I)
chr25_-_19648154 5.18 ENSDART00000148570
atp2b1b
ATPase plasma membrane Ca2+ transporting 1b
chr5_-_57820873 5.18 ENSDART00000089961
sik2a
salt-inducible kinase 2a
chr7_+_67494107 5.08 ENSDART00000185653
cpne7
copine VII
chr25_+_3327071 4.85 ENSDART00000136131
ENSDART00000133243
ldhbb
lactate dehydrogenase Bb
chr16_+_26012569 4.83 ENSDART00000148846
prss59.1
protease, serine, 59, tandem duplicate 1
chr9_-_42861080 4.79 ENSDART00000193688
ttn.1
titin, tandem duplicate 1
chr4_+_47736069 4.79 ENSDART00000193329
si:ch211-196f19.1
si:ch211-196f19.1
chr21_-_32487061 4.71 ENSDART00000114359
ENSDART00000131591
ENSDART00000131477
si:dkeyp-72g9.4
si:dkeyp-72g9.4
chr7_+_568819 4.70 ENSDART00000173716
nrxn2b
neurexin 2b
chr10_-_42685512 4.63 ENSDART00000081347
stc1l
stanniocalcin 1, like
chr19_+_9344171 4.60 ENSDART00000133447
ENSDART00000104622
si:ch211-288g17.4
si:ch211-288g17.4
chr17_-_25737452 4.58 ENSDART00000152021
si:ch211-214p16.3
si:ch211-214p16.3
chr3_+_16762483 4.57 ENSDART00000132732
tmem86b
transmembrane protein 86B
chr20_+_43942278 4.57 ENSDART00000100571
clic5b
chloride intracellular channel 5b
chr10_-_32524771 4.51 ENSDART00000066793
dgat2
diacylglycerol O-acyltransferase 2
chr5_-_10768258 4.51 ENSDART00000157043
rtn4r
reticulon 4 receptor
chr6_-_28980756 4.51 ENSDART00000014661
glmnb
glomulin, FKBP associated protein b
chr21_+_19008168 4.50 ENSDART00000136196
ENSDART00000128381
ENSDART00000176624
nefla
neurofilament, light polypeptide a
chr8_-_21372446 4.43 ENSDART00000061481
ENSDART00000079293
ela2l
elastase 2 like
chr12_+_45200744 4.42 ENSDART00000098932
wbp2
WW domain binding protein 2
chr21_+_30563115 4.37 ENSDART00000028566
si:ch211-200p22.4
si:ch211-200p22.4
chr11_+_30513656 4.35 ENSDART00000008594
tmem178
transmembrane protein 178
chr21_+_25231160 4.34 ENSDART00000063089
ENSDART00000139127
gng8
guanine nucleotide binding protein (G protein), gamma 8
chr8_-_44015210 4.33 ENSDART00000186879
ENSDART00000188965
ENSDART00000001313
ENSDART00000188902
ENSDART00000185935
ENSDART00000147869
rimbp2
rimbp2
RIMS binding protein 2
RIMS binding protein 2
chr2_-_58201173 4.22 ENSDART00000166282
pnp5b
purine nucleoside phosphorylase 5b
chr5_+_21891305 4.19 ENSDART00000136788
si:ch73-92i20.1
si:ch73-92i20.1
chr20_-_1151265 4.19 ENSDART00000012376
gabrr1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr19_+_20724347 4.18 ENSDART00000090757
kat2b
K(lysine) acetyltransferase 2B
chr4_+_5531583 4.17 ENSDART00000137500
ENSDART00000042080
si:dkey-14d8.6
si:dkey-14d8.6
chr5_-_69934558 4.07 ENSDART00000124954
ugt2a4
UDP glucuronosyltransferase 2 family, polypeptide A4
chr10_+_10677697 4.00 ENSDART00000188705
fam163b
family with sequence similarity 163, member B
chr22_+_19290199 3.95 ENSDART00000148173
si:dkey-21e2.15
si:dkey-21e2.15
chr18_+_910992 3.89 ENSDART00000161206
ENSDART00000167229
pkma
pyruvate kinase M1/2a
chr24_-_17023392 3.88 ENSDART00000106058
ptgdsb.2
prostaglandin D2 synthase b, tandem duplicate 2
chr6_-_35439406 3.81 ENSDART00000073784
rgs5a
regulator of G protein signaling 5a
chr17_-_45254585 3.78 ENSDART00000185507
ENSDART00000172080
ttbk2a
tau tubulin kinase 2a
chr1_+_45080897 3.76 ENSDART00000129819
si:ch211-151p13.8
si:ch211-151p13.8
chr2_-_4797512 3.76 ENSDART00000160765
tnk2b
tyrosine kinase, non-receptor, 2b
chr17_+_33340675 3.71 ENSDART00000184396
ENSDART00000077553
xdh
xanthine dehydrogenase
chr8_-_14052349 3.63 ENSDART00000135811
atp2b3a
ATPase plasma membrane Ca2+ transporting 3a
chr15_+_44472356 3.63 ENSDART00000155763
ENSDART00000028011
msantd4
Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
chr10_+_1638876 3.63 ENSDART00000184484
ENSDART00000060946
ENSDART00000181251
sgsm1b
small G protein signaling modulator 1b
chr20_-_27857676 3.58 ENSDART00000192934
syndig1l
synapse differentiation inducing 1-like
chr6_+_51773873 3.53 ENSDART00000156516
tmem74b
transmembrane protein 74B
chr2_-_19109304 3.50 ENSDART00000168028
si:dkey-225f23.5
si:dkey-225f23.5
chr2_-_24289641 3.50 ENSDART00000128784
ENSDART00000123565
ENSDART00000141922
ENSDART00000184550
ENSDART00000191469
myh7l
myosin heavy chain 7-like
chr6_+_2190214 3.46 ENSDART00000156716
acvr1bb
activin A receptor type 1Bb
chr23_-_45504991 3.46 ENSDART00000148761
col24a1
collagen type XXIV alpha 1
chr22_+_19289970 3.45 ENSDART00000137976
ENSDART00000132386
si:dkey-21e2.15
si:dkey-21e2.15
chr11_+_28476298 3.43 ENSDART00000122319
lrrc38b
leucine rich repeat containing 38b
chr22_+_19188809 3.41 ENSDART00000134791
ENSDART00000133682
si:dkey-21e2.8
si:dkey-21e2.8
chr15_+_45563656 3.40 ENSDART00000157501
cldn15lb
claudin 15-like b
chr4_+_5537101 3.31 ENSDART00000008692
si:dkey-14d8.7
si:dkey-14d8.7
chr4_+_17280868 3.29 ENSDART00000145349
bcat1
branched chain amino-acid transaminase 1, cytosolic
chr22_-_21150845 3.29 ENSDART00000027345
tmem59l
transmembrane protein 59-like
chr25_+_7982979 3.29 ENSDART00000171904
ucmab
upper zone of growth plate and cartilage matrix associated b
chr11_-_29650930 3.27 ENSDART00000166969
chd5
chromodomain helicase DNA binding protein 5
chr1_-_54718863 3.21 ENSDART00000122601
pgam1b
phosphoglycerate mutase 1b
chr19_-_5103313 3.16 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr7_+_58699900 3.08 ENSDART00000144009
sdr16c5b
short chain dehydrogenase/reductase family 16C, member 5b
chr3_+_20012891 3.08 ENSDART00000078974
tmub2
transmembrane and ubiquitin-like domain containing 2
chr1_+_44826593 3.08 ENSDART00000162200
STX3
zgc:165520
chr24_+_32472155 3.07 ENSDART00000098859
neurod6a
neuronal differentiation 6a
chr20_+_5564042 3.06 ENSDART00000090934
ENSDART00000127050
nrxn3b
neurexin 3b
chr6_+_52235441 3.06 ENSDART00000056319
cox6c
cytochrome c oxidase subunit VIc
chr2_+_53359234 3.06 ENSDART00000147581
celf5b
cugbp, Elav-like family member 5b
chr6_+_40714811 3.04 ENSDART00000153868
ccdc36
coiled-coil domain containing 36
chr24_+_33802528 3.03 ENSDART00000136040
ENSDART00000147499
ENSDART00000182322
atg9b
autophagy related 9B
chr25_-_35599887 3.03 ENSDART00000153827
clpxb
caseinolytic mitochondrial matrix peptidase chaperone subunit b
chr15_+_45994123 2.99 ENSDART00000124704
lrfn1
leucine rich repeat and fibronectin type III domain containing 1
chr4_+_2620751 2.99 ENSDART00000013924
gpr22a
G protein-coupled receptor 22a
chr6_+_46481024 2.98 ENSDART00000155596
si:dkey-7k24.5
si:dkey-7k24.5
chr19_+_47311020 2.94 ENSDART00000138295
ext1c
exostoses (multiple) 1c
chr22_+_33362552 2.93 ENSDART00000101580
nicn1
nicolin 1
chr6_-_607063 2.92 ENSDART00000189900
lgals2b
lectin, galactoside-binding, soluble, 2b
chr24_+_37080771 2.88 ENSDART00000159942
kcnc3b
potassium voltage-gated channel, Shaw-related subfamily, member 3b
chr11_-_10770053 2.88 ENSDART00000179213
slc4a10a
solute carrier family 4, sodium bicarbonate transporter, member 10a
chr10_+_45128375 2.88 ENSDART00000164805
camk2b2
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr7_-_16205471 2.88 ENSDART00000173584
btr05
bloodthirsty-related gene family, member 5
chr14_-_9199968 2.88 ENSDART00000146113
arhgef9b
Cdc42 guanine nucleotide exchange factor (GEF) 9b
chr12_-_45304971 2.87 ENSDART00000186537
ENSDART00000126405
fdxr
ferredoxin reductase
chr2_+_37110504 2.85 ENSDART00000132794
ENSDART00000042974
slc1a8b
solute carrier family 1 (glutamate transporter), member 8b
chr7_-_38638276 2.84 ENSDART00000074463
c6ast4
six-cysteine containing astacin protease 4
chr10_-_19523752 2.82 ENSDART00000160057
si:ch211-127i16.2
si:ch211-127i16.2
chr1_-_1627487 2.82 ENSDART00000166094
clic6
chloride intracellular channel 6
chr21_+_25226558 2.81 ENSDART00000168480
sycn.2
syncollin, tandem duplicate 2
chr3_+_61185660 2.78 ENSDART00000167114
CR352263.1

chr15_-_7598542 2.77 ENSDART00000173092
gbe1b
glucan (1,4-alpha-), branching enzyme 1b
chr10_+_21737745 2.77 ENSDART00000170498
ENSDART00000167997
pcdh1g18
protocadherin 1 gamma 18
chr19_-_5103141 2.75 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr15_-_7598294 2.74 ENSDART00000165898
gbe1b
glucan (1,4-alpha-), branching enzyme 1b
chr2_+_10134345 2.73 ENSDART00000100725
ahsg2
alpha-2-HS-glycoprotein 2
chr3_+_4997545 2.73 ENSDART00000181237
CABZ01117706.1

chr17_-_12389259 2.72 ENSDART00000185724
snap25b
synaptosomal-associated protein, 25b
chr9_+_7909490 2.70 ENSDART00000133063
ENSDART00000109288
myo16
myosin XVI
chr24_-_40009446 2.68 ENSDART00000087422
aoc1
amine oxidase, copper containing 1
chr11_-_25213651 2.66 ENSDART00000097316
ENSDART00000152186
myh7ba
myosin, heavy chain 7B, cardiac muscle, beta a
chr5_+_5689476 2.63 ENSDART00000022729
unm_sa808
un-named sa808
chr3_+_43460696 2.63 ENSDART00000164581
galr2b
galanin receptor 2b
chr2_-_9646857 2.62 ENSDART00000056901
zgc:153615
zgc:153615
chr20_-_34090740 2.62 ENSDART00000062539
ENSDART00000008140
pdcb
phosducin b
chr3_+_1182315 2.61 ENSDART00000055430
ndufa6
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6
chr17_-_38887424 2.60 ENSDART00000141177
slc24a4a
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4a
chr16_-_13281380 2.60 ENSDART00000103882
grin2db
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr11_-_11471857 2.60 ENSDART00000030103
krt94
keratin 94
chr6_-_10320676 2.60 ENSDART00000151247
scn1lab
sodium channel, voltage-gated, type I like, alpha b
chr5_+_69981453 2.56 ENSDART00000143860
si:ch211-154e10.1
si:ch211-154e10.1
chr10_+_35952532 2.55 ENSDART00000184730
rtn4rl1a
reticulon 4 receptor-like 1a
chr1_-_50859053 2.55 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr19_-_38872650 2.55 ENSDART00000146641
adgrb2
adhesion G protein-coupled receptor B2
chr5_-_42544522 2.53 ENSDART00000157968
BX510949.1

chr3_+_42923275 2.53 ENSDART00000168228
tmem184a
transmembrane protein 184a
chr21_+_5882300 2.53 ENSDART00000165065
uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr25_+_5604512 2.52 ENSDART00000042781
plxnb2b
plexin b2b
chr3_-_34724879 2.51 ENSDART00000177021
thraa
thyroid hormone receptor alpha a
chr10_-_5814101 2.50 ENSDART00000161903
il6st
interleukin 6 signal transducer
chr8_-_39903803 2.49 ENSDART00000012391
cabp1a
calcium binding protein 1a
chr7_+_48761875 2.48 ENSDART00000003690
acana
aggrecan a
chr11_+_36989696 2.46 ENSDART00000045888
tkta
transketolase a
chr3_-_28828569 2.46 ENSDART00000167679
si:ch211-76l23.4
si:ch211-76l23.4
chr20_+_49119633 2.44 ENSDART00000151435
cd109
CD109 molecule
chr7_-_50633285 2.43 ENSDART00000174018
crtc3
CREB regulated transcription coactivator 3
chr25_+_25124684 2.43 ENSDART00000167542
ldha
lactate dehydrogenase A4
chr4_-_11163112 2.40 ENSDART00000188854
prmt8b
protein arginine methyltransferase 8b
chr9_-_52678146 2.40 ENSDART00000169179
pfkla
phosphofructokinase, liver a
chr6_-_10835849 2.40 ENSDART00000005903
ENSDART00000135065
atp5mc3b
ATP synthase membrane subunit c locus 3b
chr19_-_5805923 2.38 ENSDART00000134340
si:ch211-264f5.8
si:ch211-264f5.8
chr21_+_25221940 2.37 ENSDART00000108972
sycn.1
syncollin, tandem duplicate 1
chr16_-_45058919 2.32 ENSDART00000177134
gapdhs
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr8_-_39760427 2.31 ENSDART00000184336
ENSDART00000186500
si:ch211-170d8.8
si:ch211-170d8.8
chr7_+_58699718 2.30 ENSDART00000049264
sdr16c5b
short chain dehydrogenase/reductase family 16C, member 5b
chr5_-_38064065 2.26 ENSDART00000137181
si:dkey-111e8.5
si:dkey-111e8.5
chr7_+_9904627 2.25 ENSDART00000172824
cers3a
ceramide synthase 3a
chr5_-_57879138 2.25 ENSDART00000145959
sik2a
salt-inducible kinase 2a
chr3_-_41795917 2.20 ENSDART00000182662
grifin
galectin-related inter-fiber protein
chr1_-_55810730 2.18 ENSDART00000100551
zgc:136908
zgc:136908
chr23_+_6272638 2.16 ENSDART00000190366
syt2a
synaptotagmin IIa
chr18_-_226800 2.16 ENSDART00000165180
tarsl2
threonyl-tRNA synthetase-like 2
chr7_+_58686860 2.14 ENSDART00000052332
penkb
proenkephalin b
chr8_-_49908978 2.14 ENSDART00000172642
agtpbp1
ATP/GTP binding protein 1
chr23_+_42434348 2.14 ENSDART00000161027
cyp2aa1
cytochrome P450, family 2, subfamily AA, polypeptide 1
chr13_-_20540790 2.13 ENSDART00000131467
si:ch1073-126c3.2
si:ch1073-126c3.2
chr5_-_15524782 2.13 ENSDART00000189781
CU694999.1

chr16_+_11724230 2.12 ENSDART00000060266
ceacam1
carcinoembryonic antigen-related cell adhesion molecule 1
chr2_-_8102169 2.12 ENSDART00000131955
pls1
plastin 1 (I isoform)
chr4_-_11165611 2.12 ENSDART00000059489
prmt8b
protein arginine methyltransferase 8b
chr12_+_47162761 2.11 ENSDART00000192339
ENSDART00000167726
RYR2
ryanodine receptor 2
chr4_-_11165961 2.10 ENSDART00000193393
prmt8b
protein arginine methyltransferase 8b
chr17_-_29192987 2.07 ENSDART00000164302
sptbn5
spectrin, beta, non-erythrocytic 5
chr17_-_51202339 2.07 ENSDART00000167117
si:ch1073-469d17.2
si:ch1073-469d17.2
chr20_-_39271844 2.05 ENSDART00000192708
clu
clusterin
chr5_-_37103487 2.05 ENSDART00000149211
il13ra2
interleukin 13 receptor, alpha 2
chr3_-_32337653 2.05 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
si:dkey-16p21.8
chr5_+_28830388 2.03 ENSDART00000149150
serpina7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr22_+_7742211 2.02 ENSDART00000140896
CELA1 (1 of many)
zgc:92511
chr5_-_24044877 2.01 ENSDART00000161131
pdha1a
pyruvate dehydrogenase E1 alpha 1 subunit a
chr16_-_50181206 2.01 ENSDART00000148478
lim2.5
lens intrinsic membrane protein 2.5
chr9_-_42873700 2.01 ENSDART00000125953
ttn.1
titin, tandem duplicate 1
chr22_+_9472814 1.99 ENSDART00000112125
ENSDART00000138850
cacna2d2b
calcium channel, voltage-dependent, alpha 2/delta subunit 2b
chr20_+_1412193 1.99 ENSDART00000064419
leg1.1
liver-enriched gene 1, tandem duplicate 1
chr5_-_35301800 1.97 ENSDART00000085142
map1b
microtubule-associated protein 1B
chr2_+_55982300 1.97 ENSDART00000183903
nmrk2
nicotinamide riboside kinase 2
chr7_+_9981757 1.95 ENSDART00000113429
ENSDART00000173233
adamts17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr17_-_33289304 1.95 ENSDART00000135118
ENSDART00000040346
efr3ba
EFR3 homolog Ba (S. cerevisiae)
chr1_-_50838160 1.95 ENSDART00000163939
ENSDART00000165111
zgc:154142
zgc:154142
chr8_-_39739056 1.95 ENSDART00000147992
si:ch211-170d8.5
si:ch211-170d8.5
chr25_+_31238606 1.95 ENSDART00000149439
tnni2a.2
troponin I type 2a (skeletal, fast), tandem duplicate 2
chr5_-_69314495 1.93 ENSDART00000182335
smtnb
smoothelin b
chr10_+_22782522 1.92 ENSDART00000079498
ENSDART00000145558
si:ch211-237l4.6
si:ch211-237l4.6
chr11_-_18791834 1.92 ENSDART00000156431
pfkfb2b
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b
chr12_+_47162456 1.91 ENSDART00000186272
ENSDART00000180811
RYR2
ryanodine receptor 2
chr20_-_1141722 1.90 ENSDART00000152675
gabrr1
gamma-aminobutyric acid (GABA) A receptor, rho 1

Network of associatons between targets according to the STRING database.

First level regulatory network of esrrd+esrrga_esrrb_esrra+esrrgb

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.3 GO:0015824 proline transport(GO:0015824)
2.2 8.6 GO:0072673 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
1.5 6.1 GO:0070317 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
1.5 5.9 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
1.5 4.4 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
1.4 5.6 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
1.4 4.2 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
1.4 12.4 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
1.2 3.7 GO:0006145 purine nucleobase catabolic process(GO:0006145)
1.0 12.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.9 12.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.9 11.7 GO:0042572 retinol metabolic process(GO:0042572)
0.8 6.8 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.8 3.3 GO:0009098 leucine biosynthetic process(GO:0009098)
0.8 1.6 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.7 3.7 GO:0046677 response to antibiotic(GO:0046677)
0.7 4.4 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.7 2.2 GO:0051228 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.6 1.2 GO:0051196 regulation of glycolytic process(GO:0006110) regulation of nucleotide catabolic process(GO:0030811) regulation of cofactor metabolic process(GO:0051193) regulation of coenzyme metabolic process(GO:0051196)
0.6 3.5 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.5 2.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.5 6.2 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.5 2.5 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.4 2.6 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.4 1.3 GO:0009750 response to fructose(GO:0009750)
0.4 2.6 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.4 6.8 GO:0048769 sarcomerogenesis(GO:0048769)
0.4 1.3 GO:0097401 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.4 1.3 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.4 1.2 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.4 4.5 GO:0099558 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.4 1.6 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.4 3.0 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.4 11.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.4 2.5 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.3 2.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.3 3.8 GO:0061718 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.3 1.0 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.3 1.9 GO:0035889 otolith tethering(GO:0035889)
0.3 0.9 GO:0009099 valine biosynthetic process(GO:0009099)
0.3 4.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.3 3.0 GO:0044805 late nucleophagy(GO:0044805)
0.3 1.5 GO:0030329 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.3 5.1 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.3 2.3 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.3 1.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.3 2.5 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.2 1.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.2 1.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.2 1.8 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.2 0.9 GO:0051660 establishment of centrosome localization(GO:0051660)
0.2 2.9 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.2 0.9 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.2 14.1 GO:0051592 response to calcium ion(GO:0051592)
0.2 1.1 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.2 3.3 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.2 1.7 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.2 5.8 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.2 1.2 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.2 4.5 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.2 0.8 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.2 3.8 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.2 2.0 GO:1990402 embryonic liver development(GO:1990402)
0.2 43.2 GO:0007601 visual perception(GO:0007601)
0.2 7.5 GO:0030199 collagen fibril organization(GO:0030199)
0.2 1.9 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2 0.9 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 0.7 GO:0060074 synapse maturation(GO:0060074)
0.2 0.5 GO:0009397 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.2 1.0 GO:0032218 riboflavin transport(GO:0032218)
0.2 3.5 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.2 0.6 GO:0045938 regulation of endocrine process(GO:0044060) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) endocrine hormone secretion(GO:0060986)
0.2 1.1 GO:0010460 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.2 0.6 GO:0006844 acyl carnitine transport(GO:0006844)
0.2 5.7 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.2 0.9 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.2 0.5 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.6 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.1 0.7 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.7 GO:0098586 cytoplasmic pattern recognition receptor signaling pathway in response to virus(GO:0039528) cellular response to virus(GO:0098586)
0.1 1.4 GO:0098869 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 1.6 GO:0032264 IMP salvage(GO:0032264)
0.1 1.4 GO:0006108 malate metabolic process(GO:0006108)
0.1 2.6 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.1 1.9 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.7 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.1 0.7 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 1.2 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.1 2.6 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 0.9 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.1 2.8 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.4 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 2.9 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 4.1 GO:0006119 oxidative phosphorylation(GO:0006119)
0.1 0.4 GO:0021985 parturition(GO:0007567) neurohypophysis development(GO:0021985) maternal process involved in parturition(GO:0060137)
0.1 4.4 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.1 0.5 GO:0006531 aspartate metabolic process(GO:0006531)
0.1 4.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 3.0 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.1 1.8 GO:0099590 positive regulation of synaptic transmission, glutamatergic(GO:0051968) neurotransmitter receptor internalization(GO:0099590)
0.1 4.9 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 1.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.6 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 3.7 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.1 0.8 GO:0060976 coronary vasculature development(GO:0060976)
0.1 0.4 GO:0032475 otolith formation(GO:0032475)
0.1 1.0 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 1.1 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 5.7 GO:0051781 positive regulation of cell division(GO:0051781)
0.1 0.5 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 0.4 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 1.9 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 2.9 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.1 3.2 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.2 GO:0019233 sensory perception of pain(GO:0019233)
0.1 0.4 GO:0055091 phospholipid homeostasis(GO:0055091)
0.1 1.8 GO:0006825 copper ion transport(GO:0006825)
0.1 0.5 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.8 GO:0007608 sensory perception of smell(GO:0007608)
0.1 1.2 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.1 1.6 GO:0002027 regulation of heart rate(GO:0002027)
0.1 2.8 GO:0006096 glycolytic process(GO:0006096)
0.1 0.3 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.1 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.1 3.0 GO:0071346 cellular response to interferon-gamma(GO:0071346)
0.1 2.6 GO:0046847 filopodium assembly(GO:0046847)
0.1 16.7 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.1 0.9 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 0.9 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 3.1 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.1 0.5 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 1.0 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 1.5 GO:0006415 translational termination(GO:0006415)
0.1 1.9 GO:0046328 regulation of JNK cascade(GO:0046328)
0.1 2.1 GO:1901214 regulation of neuron death(GO:1901214)
0.1 0.7 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.1 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway(GO:0002753)
0.1 0.5 GO:0048069 eye pigmentation(GO:0048069)
0.1 1.0 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.4 GO:0050909 sensory perception of taste(GO:0050909)
0.1 1.8 GO:0051923 sulfation(GO:0051923)
0.1 0.1 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 0.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.6 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 4.6 GO:0007605 sensory perception of sound(GO:0007605)
0.1 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.1 GO:0008207 C21-steroid hormone metabolic process(GO:0008207)
0.1 1.2 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.1 3.6 GO:0030042 actin filament depolymerization(GO:0030042)
0.1 1.1 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 1.0 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 3.3 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.1 2.3 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 2.2 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.9 GO:0006536 glutamate metabolic process(GO:0006536)
0.0 1.3 GO:0006826 iron ion transport(GO:0006826)
0.0 1.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:0060347 ventricular trabecula myocardium morphogenesis(GO:0003222) trabecula formation(GO:0060343) heart trabecula formation(GO:0060347) skin epidermis development(GO:0098773)
0.0 1.5 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.6 GO:0072576 liver morphogenesis(GO:0072576)
0.0 0.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.3 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 1.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 3.5 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.3 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.5 GO:0060337 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.2 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.2 GO:0006788 heme oxidation(GO:0006788)
0.0 4.0 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.2 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.3 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 1.8 GO:2000181 negative regulation of angiogenesis(GO:0016525) negative regulation of blood vessel morphogenesis(GO:2000181)
0.0 2.4 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.3 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 2.9 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 1.1 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.1 GO:0002320 lymphoid progenitor cell differentiation(GO:0002320)
0.0 0.5 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 6.3 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.4 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 2.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.1 GO:0001964 startle response(GO:0001964)
0.0 0.2 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.9 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.7 GO:0003094 glomerular filtration(GO:0003094)
0.0 1.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.4 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 4.0 GO:0048675 axon extension(GO:0048675)
0.0 1.2 GO:0048484 enteric nervous system development(GO:0048484)
0.0 1.2 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.7 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.4 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 1.0 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.5 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.4 GO:0015669 gas transport(GO:0015669)
0.0 0.1 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.4 GO:0008217 regulation of blood pressure(GO:0008217)
0.0 0.4 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 16.2 GO:0006508 proteolysis(GO:0006508)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 8.6 GO:0005975 carbohydrate metabolic process(GO:0005975)
0.0 0.3 GO:0030168 platelet activation(GO:0030168)
0.0 2.6 GO:0055001 muscle cell development(GO:0055001)
0.0 0.5 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 1.4 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 9.6 GO:0016567 protein ubiquitination(GO:0016567)
0.0 0.8 GO:0016358 dendrite development(GO:0016358)
0.0 1.2 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.7 GO:0007338 single fertilization(GO:0007338)
0.0 0.0 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.6 GO:0006936 muscle contraction(GO:0006936)
0.0 0.7 GO:0006334 nucleosome assembly(GO:0006334)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) anchored component of the cytoplasmic side of the plasma membrane(GO:0098753)
2.1 12.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
1.7 8.6 GO:0032433 filopodium tip(GO:0032433)
1.2 3.5 GO:0005592 collagen type XI trimer(GO:0005592)
0.9 6.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.9 2.6 GO:1902560 GMP reductase complex(GO:1902560)
0.8 6.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.5 2.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.5 5.6 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.4 2.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.4 2.6 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.4 2.1 GO:0042583 chromaffin granule(GO:0042583)
0.4 7.1 GO:0030667 secretory granule membrane(GO:0030667)
0.4 1.6 GO:0097268 cytoophidium(GO:0097268)
0.3 3.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.3 4.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.3 1.3 GO:0043291 RAVE complex(GO:0043291)
0.3 0.9 GO:0005948 acetolactate synthase complex(GO:0005948)
0.3 5.5 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.3 4.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.3 3.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 17.9 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.2 0.9 GO:0061702 inflammasome complex(GO:0061702)
0.2 13.8 GO:0034707 chloride channel complex(GO:0034707)
0.2 2.9 GO:0048179 activin receptor complex(GO:0048179)
0.2 8.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.2 5.1 GO:0032589 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.2 0.7 GO:0005588 collagen type V trimer(GO:0005588)
0.2 0.8 GO:0008091 spectrin(GO:0008091)
0.2 0.3 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.2 4.8 GO:0031594 neuromuscular junction(GO:0031594)
0.2 0.5 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 1.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 2.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.9 GO:0001650 fibrillar center(GO:0001650)
0.1 6.4 GO:0005811 lipid particle(GO:0005811)
0.1 4.5 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 3.5 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.1 3.0 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 2.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 1.5 GO:0005581 collagen trimer(GO:0005581)
0.1 2.2 GO:0031430 M band(GO:0031430)
0.1 0.4 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.1 2.8 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 0.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 1.9 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 1.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 3.3 GO:0035869 ciliary transition zone(GO:0035869)
0.1 1.1 GO:0042627 chylomicron(GO:0042627)
0.1 0.4 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.8 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 1.3 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1 3.2 GO:0005861 troponin complex(GO:0005861)
0.1 1.0 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 7.5 GO:0043025 neuronal cell body(GO:0043025)
0.1 0.9 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 9.8 GO:0008021 synaptic vesicle(GO:0008021)
0.1 2.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.9 GO:0030315 T-tubule(GO:0030315)
0.1 4.8 GO:0043235 receptor complex(GO:0043235)
0.1 6.6 GO:0016459 myosin complex(GO:0016459)
0.1 2.4 GO:0031941 filamentous actin(GO:0031941)
0.1 2.8 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 2.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.7 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 1.0 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.2 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.4 GO:0031526 brush border membrane(GO:0031526)
0.0 2.6 GO:0005884 actin filament(GO:0005884)
0.0 1.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 4.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 43.3 GO:0005615 extracellular space(GO:0005615)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 7.0 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.5 GO:0008305 integrin complex(GO:0008305)
0.0 2.9 GO:0005882 intermediate filament(GO:0005882)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 3.9 GO:0043296 apical junction complex(GO:0043296)
0.0 36.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 2.0 GO:0060076 postsynaptic density(GO:0014069) excitatory synapse(GO:0060076)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 14.7 GO:0005576 extracellular region(GO:0005576)
0.0 1.0 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 3.3 GO:0045202 synapse(GO:0045202)
0.0 1.2 GO:0005769 early endosome(GO:0005769)
0.0 1.7 GO:0030424 axon(GO:0030424)
0.0 0.3 GO:0030427 site of polarized growth(GO:0030427)
0.0 8.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.7 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.5 GO:0016605 PML body(GO:0016605)
0.0 1.9 GO:0043005 neuron projection(GO:0043005)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 14.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
1.5 4.5 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
1.5 5.9 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
1.4 5.5 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
1.3 5.3 GO:0070324 thyroid hormone binding(GO:0070324)
1.3 7.5 GO:0032052 bile acid binding(GO:0032052)
0.9 6.6 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.9 25.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.9 2.6 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.8 6.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.8 3.3 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.8 6.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.7 2.9 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.7 2.2 GO:0048030 disaccharide binding(GO:0048030)
0.6 3.9 GO:0004743 pyruvate kinase activity(GO:0004743)
0.6 3.2 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.6 3.5 GO:0016361 activin receptor activity, type I(GO:0016361)
0.6 4.6 GO:0016803 ether hydrolase activity(GO:0016803)
0.6 3.4 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.5 2.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.5 4.2 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.5 2.6 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.5 1.5 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.5 3.3 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.5 4.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.5 4.5 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.4 2.6 GO:0004966 galanin receptor activity(GO:0004966)
0.4 5.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.4 5.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.4 3.7 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.4 11.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.4 2.0 GO:0016531 copper chaperone activity(GO:0016531)
0.4 1.6 GO:0003883 CTP synthase activity(GO:0003883)
0.3 2.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 1.0 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.3 1.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.3 12.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 1.2 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.3 1.5 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.3 2.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.3 4.5 GO:0048495 Roundabout binding(GO:0048495)
0.3 0.8 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.3 2.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.3 21.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 0.7 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.2 1.5 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.2 0.7 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 0.9 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.2 1.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.2 0.7 GO:0003913 DNA photolyase activity(GO:0003913)
0.2 1.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.2 1.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 8.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2 4.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 2.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 1.4 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.2 3.5 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.2 0.8 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.2 1.0 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.2 6.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 1.4 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 2.8 GO:0016411 acylglycerol O-acyltransferase activity(GO:0016411)
0.2 0.5 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.2 2.1 GO:0031628 opioid receptor binding(GO:0031628)
0.2 1.0 GO:0032217 riboflavin transporter activity(GO:0032217)
0.2 0.6 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.2 7.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.2 2.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 19.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.5 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 1.0 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 1.2 GO:0004985 opioid receptor activity(GO:0004985)
0.1 1.6 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.4 GO:0016936 galactoside binding(GO:0016936)
0.1 0.7 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 1.0 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.1 31.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.9 GO:0008443 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) phosphofructokinase activity(GO:0008443)
0.1 1.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 1.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 2.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 2.4 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 1.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.4 GO:0004990 oxytocin receptor activity(GO:0004990)
0.1 1.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.5 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 4.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 3.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 1.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 4.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.6 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.1 2.0 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.7 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.6 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.5 GO:1990757 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.1 5.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.9 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 4.8 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.5 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 1.1 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 6.1 GO:0005254 chloride channel activity(GO:0005254)
0.1 1.6 GO:0030552 cAMP binding(GO:0030552)
0.1 1.2 GO:0050811 GABA receptor binding(GO:0050811)
0.1 2.0 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.1 0.3 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.1 1.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 1.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.6 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 0.4 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.1 2.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 5.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.3 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 2.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 1.6 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.1 0.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.9 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 0.8 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 0.8 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 5.7 GO:0008201 heparin binding(GO:0008201)
0.1 3.2 GO:0005178 integrin binding(GO:0005178)
0.1 0.6 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 4.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 2.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.9 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 1.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.5 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 0.2 GO:0072570 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.1 0.9 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 8.1 GO:0015293 symporter activity(GO:0015293)
0.1 0.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 4.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 1.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 2.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.2 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.6 GO:0030145 manganese ion binding(GO:0030145)
0.0 1.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.4 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.4 GO:0048018 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.4 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 4.1 GO:0019955 cytokine binding(GO:0019955)
0.0 1.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.5 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 1.7 GO:0044325 ion channel binding(GO:0044325)
0.0 0.7 GO:0022839 calcium activated cation channel activity(GO:0005227) ion gated channel activity(GO:0022839)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 1.0 GO:0098632 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.9 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 1.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 6.8 GO:0003774 motor activity(GO:0003774)
0.0 1.8 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.4 GO:0045159 myosin II binding(GO:0045159)
0.0 0.8 GO:0016597 amino acid binding(GO:0016597)
0.0 10.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 3.0 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.5 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.5 GO:0022829 wide pore channel activity(GO:0022829)
0.0 2.2 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.2 GO:0005222 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 2.4 GO:0005179 hormone activity(GO:0005179)
0.0 0.0 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.8 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.5 GO:0031593 polyubiquitin binding(GO:0031593)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 0.8 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.3 2.0 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.2 3.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 6.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 0.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 4.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 2.5 PID IL27 PATHWAY IL27-mediated signaling events
0.1 6.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.2 PID FOXO PATHWAY FoxO family signaling
0.1 2.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 4.4 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.0 PID REELIN PATHWAY Reelin signaling pathway
0.1 1.6 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 0.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 2.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 4.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 1.0 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 6.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.7 PID INSULIN PATHWAY Insulin Pathway
0.0 0.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.7 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.6 1.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.6 6.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.4 1.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.4 4.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.3 6.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.3 5.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.3 2.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.3 0.5 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 2.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 6.1 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.2 3.9 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 3.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.2 5.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 2.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 1.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 3.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 6.1 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.2 8.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 4.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 1.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 0.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.0 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.2 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 0.9 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 0.7 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.9 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 2.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.3 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)