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PRJEB1986: zebrafish developmental stages transcriptome

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Results for etv7

Z-value: 0.80

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Transcription factors associated with etv7

Gene Symbol Gene ID Gene Info
etv7
ENSDARG00000089434 ETS variant transcription factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
etv7dr11_v1_chr23_-_5101847_5101847-0.493.5e-02Click!

Activity profile of etv7 motif

Sorted Z-values of etv7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_+_32101361 2.62 ENSDART00000138849
zgc:56699
zgc:56699
chr23_+_32101202 2.60 ENSDART00000000992
zgc:56699
zgc:56699
chr20_-_37820939 2.14 ENSDART00000032978
nsl1
NSL1, MIS12 kinetochore complex component
chr20_+_39344889 1.94 ENSDART00000009164
esco2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr17_-_51121525 1.78 ENSDART00000130412
ENSDART00000013418
aqr
aquarius intron-binding spliceosomal factor
chr5_+_28497956 1.59 ENSDART00000191935
nfr
notochord formation related
chr13_-_4979029 1.59 ENSDART00000132931
nolc1
nucleolar and coiled-body phosphoprotein 1
chr13_-_33700461 1.59 ENSDART00000160520
mad2l1bp
MAD2L1 binding protein
chr6_+_60125033 1.53 ENSDART00000148557
ENSDART00000008224
aurka
aurora kinase A
chr13_+_5978809 1.53 ENSDART00000102563
ENSDART00000121598
phf10
PHD finger protein 10
chr22_+_9862243 1.48 ENSDART00000105942
si:dkey-253d23.3
si:dkey-253d23.3
chr16_+_13860299 1.33 ENSDART00000121998
grwd1
glutamate-rich WD repeat containing 1
chr23_-_45318760 1.31 ENSDART00000166883
ccdc171
coiled-coil domain containing 171
chr13_+_6188759 1.28 ENSDART00000161062
ppm1g
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr7_+_46019780 1.26 ENSDART00000163991
ccne1
cyclin E1
chr3_-_15444396 1.23 ENSDART00000104361
si:dkey-56d12.4
si:dkey-56d12.4
chr3_+_301479 1.22 ENSDART00000165169
CABZ01075611.1

chr22_+_9862466 1.22 ENSDART00000146864
si:dkey-253d23.3
si:dkey-253d23.3
chr22_+_17118225 1.22 ENSDART00000135604
frem1b
Fras1 related extracellular matrix 1b
chr17_+_34244345 1.20 ENSDART00000006058
eif2s1a
eukaryotic translation initiation factor 2, subunit 1 alpha a
chr7_-_33351485 1.20 ENSDART00000146420
anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr13_+_39532050 1.20 ENSDART00000019379
marveld1
MARVEL domain containing 1
chr19_-_37508571 1.19 ENSDART00000018255
ilf2
interleukin enhancer binding factor 2
chr23_+_39611688 1.17 ENSDART00000034690
otud3
OTU deubiquitinase 3
chr11_+_3959495 1.17 ENSDART00000122953
gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr8_-_31053872 1.15 ENSDART00000109885
snrnp200
small nuclear ribonucleoprotein 200 (U5)
chr10_+_17747880 1.14 ENSDART00000135044
pigo
phosphatidylinositol glycan anchor biosynthesis, class O
chr8_-_17184482 1.14 ENSDART00000025803
pola2
polymerase (DNA directed), alpha 2
chr13_+_6189203 1.14 ENSDART00000109665
ppm1g
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr7_+_756942 1.11 ENSDART00000152224
zgc:63470
zgc:63470
chr13_+_9559461 1.10 ENSDART00000047740
wdr32
WD repeat domain 32
chr14_-_10617923 1.09 ENSDART00000133723
ENSDART00000131939
ENSDART00000136649
si:dkey-92i17.2
si:dkey-92i17.2
chr22_+_16535575 1.09 ENSDART00000083063
tal1
T-cell acute lymphocytic leukemia 1
chr16_+_38338721 1.07 ENSDART00000076528
ENSDART00000142885
gabpb2b
GA binding protein transcription factor, beta subunit 2b
chr18_-_50799510 1.04 ENSDART00000174373
taldo1
transaldolase 1
chr25_+_16880990 1.01 ENSDART00000020259
zgc:77158
zgc:77158
chr1_+_11107688 1.00 ENSDART00000109858
knstrn
kinetochore-localized astrin/SPAG5 binding protein
chr17_+_43863708 0.99 ENSDART00000133874
ENSDART00000140316
ENSDART00000142929
ENSDART00000148090
zgc:66313
zgc:66313
chr16_+_38337783 0.98 ENSDART00000135008
gabpb2b
GA binding protein transcription factor, beta subunit 2b
chr7_-_26049282 0.97 ENSDART00000136389
ENSDART00000101124
rnaseka
ribonuclease, RNase K a
chr8_+_7854130 0.97 ENSDART00000165575
cxxc1a
CXXC finger protein 1a
chr18_-_40884087 0.97 ENSDART00000059194
snrpd2
small nuclear ribonucleoprotein D2 polypeptide
chr22_-_22242884 0.95 ENSDART00000020937
hdgfl2
HDGF like 2
chr19_+_7495791 0.92 ENSDART00000010862
mrpl24
mitochondrial ribosomal protein L24
chr15_-_25365570 0.92 ENSDART00000152754
cluha
clustered mitochondria (cluA/CLU1) homolog a
chr8_+_387622 0.91 ENSDART00000167361
pym1
PYM homolog 1, exon junction complex associated factor
chr17_-_43863700 0.89 ENSDART00000157530
ahsa1b
AHA1, activator of heat shock protein ATPase homolog 1b
chr25_+_245438 0.89 ENSDART00000004689
zgc:92481
zgc:92481
chr7_+_44608224 0.85 ENSDART00000005033
cmtm3
CKLF-like MARVEL transmembrane domain containing 3
chr21_-_18932761 0.82 ENSDART00000140129
med15
mediator complex subunit 15
chr15_+_37545855 0.82 ENSDART00000099456
psenen
presenilin enhancer gamma secretase subunit
chr22_-_506522 0.82 ENSDART00000106645
ENSDART00000067637
dstyk
dual serine/threonine and tyrosine protein kinase
chr16_-_9453591 0.82 ENSDART00000126154
prpf3
PRP3 pre-mRNA processing factor 3 homolog (yeast)
chr14_+_23668730 0.80 ENSDART00000157741
med12
mediator complex subunit 12
chr18_+_50707179 0.79 ENSDART00000160206
rap2b
RAP2B, member of RAS oncogene family
chr2_-_24317240 0.79 ENSDART00000078975
trnau1apb
tRNA selenocysteine 1 associated protein 1b
chr3_+_62140077 0.77 ENSDART00000108945
GID4
GID complex subunit 4 homolog
chr2_-_37134169 0.77 ENSDART00000146123
ENSDART00000146533
ENSDART00000040427
elavl1a
ELAV like RNA binding protein 1a
chr15_+_37546391 0.75 ENSDART00000186625
psenen
presenilin enhancer gamma secretase subunit
chr5_-_4297459 0.74 ENSDART00000018895
srrt
serrate RNA effector molecule homolog (Arabidopsis)
chr6_-_55958705 0.71 ENSDART00000155963
eya2
EYA transcriptional coactivator and phosphatase 2
chr21_+_27513859 0.70 ENSDART00000065420
pacs1a
phosphofurin acidic cluster sorting protein 1a
chr24_+_29352039 0.70 ENSDART00000101641
prmt6
protein arginine methyltransferase 6
chr1_+_54889733 0.70 ENSDART00000140375
zfyve27
zinc finger, FYVE domain containing 27
chr1_+_6225493 0.68 ENSDART00000145378
fastkd2
FAST kinase domains 2
chr7_+_44608478 0.68 ENSDART00000149981
cmtm3
CKLF-like MARVEL transmembrane domain containing 3
chr6_+_52212574 0.68 ENSDART00000025940
ywhaba
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a
chr13_-_3324764 0.67 ENSDART00000102748
ENSDART00000114040
ubr2
ubiquitin protein ligase E3 component n-recognin 2
chr5_+_483965 0.66 ENSDART00000150007
tek
TEK tyrosine kinase, endothelial
chr14_+_12178915 0.65 ENSDART00000054626
hdac3
histone deacetylase 3
chr1_+_494297 0.63 ENSDART00000108579
ENSDART00000146732
blzf1
basic leucine zipper nuclear factor 1
chr7_+_26545911 0.61 ENSDART00000135313
tnk1
tyrosine kinase, non-receptor, 1
chr25_-_3627130 0.60 ENSDART00000171863
si:ch211-272n13.3
si:ch211-272n13.3
chr5_+_3927989 0.60 ENSDART00000030125
znhit3
zinc finger, HIT-type containing 3
chr20_+_37820992 0.58 ENSDART00000064692
tatdn3
TatD DNase domain containing 3
chr21_+_21621042 0.58 ENSDART00000134907
tgfb1b
transforming growth factor, beta 1b
chr14_+_49220026 0.57 ENSDART00000063643
ENSDART00000128744
rmnd5b
required for meiotic nuclear division 5 homolog B
chr13_+_6086730 0.55 ENSDART00000049328
fam120b
family with sequence similarity 120B
chr11_+_5681762 0.54 ENSDART00000179139
arid3a
AT rich interactive domain 3A (BRIGHT-like)
chr21_-_36453594 0.54 ENSDART00000193176
cnot8
CCR4-NOT transcription complex, subunit 8
chr20_-_37831849 0.53 ENSDART00000188483
ENSDART00000153005
ENSDART00000142364
si:ch211-147d7.5
si:ch211-147d7.5
chr21_-_45073764 0.53 ENSDART00000181390
ENSDART00000063714
rapgef6
Rap guanine nucleotide exchange factor (GEF) 6
chr19_+_6904314 0.52 ENSDART00000151502
si:ch1073-127d16.1
si:ch1073-127d16.1
chr20_+_51199666 0.51 ENSDART00000169321
hsp90ab1
heat shock protein 90, alpha (cytosolic), class B member 1
chr21_+_19858627 0.51 ENSDART00000147010
fybb
FYN binding protein b
chr7_+_29177191 0.51 ENSDART00000008096
aph1b
APH1B gamma secretase subunit
chr13_-_330004 0.50 ENSDART00000093149
ddx21
DEAD (Asp-Glu-Ala-Asp) box helicase 21
chr18_+_15778110 0.48 ENSDART00000014188
ube2na
ubiquitin-conjugating enzyme E2Na
chr1_-_6225285 0.47 ENSDART00000141653
mdh1b
malate dehydrogenase 1B, NAD (soluble)
chr16_+_33931032 0.46 ENSDART00000167240
snip1
Smad nuclear interacting protein
chr1_+_54766943 0.45 ENSDART00000144759
nlrc6
NLR family CARD domain containing 6
chr5_-_68495967 0.43 ENSDART00000188107
ephb4a
eph receptor B4a
chr8_+_17184602 0.43 ENSDART00000050228
ENSDART00000140531
dimt1l
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
chr9_-_21825913 0.43 ENSDART00000101986
mrpl30
mitochondrial ribosomal protein L30
chr20_+_27093042 0.43 ENSDART00000024595
ubr7
ubiquitin protein ligase E3 component n-recognin 7
chr4_+_2637947 0.42 ENSDART00000130623
dus4l
dihydrouridine synthase 4-like (S. cerevisiae)
chr3_+_28831450 0.41 ENSDART00000055422
flr
fleer
chr22_+_16320076 0.41 ENSDART00000164161
osbpl1a
oxysterol binding protein-like 1A
chr6_+_52212927 0.40 ENSDART00000143458
ywhaba
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a
chr12_-_20409794 0.40 ENSDART00000077936
lcmt1
leucine carboxyl methyltransferase 1
chr10_-_1697037 0.40 ENSDART00000125188
ENSDART00000002985
srsf9
serine/arginine-rich splicing factor 9
chr9_+_44304980 0.39 ENSDART00000147990
ssfa2
sperm specific antigen 2
chr1_+_51407520 0.36 ENSDART00000074294
actr2a
ARP2 actin related protein 2a homolog
chr5_+_32490238 0.34 ENSDART00000191839
ndor1
NADPH dependent diflavin oxidoreductase 1
chr2_+_26479676 0.34 ENSDART00000056795
ENSDART00000144837
hectd3
HECT domain containing 3
chr22_-_347424 0.34 ENSDART00000067633
necap2
NECAP endocytosis associated 2
chr9_-_21067971 0.33 ENSDART00000004333
tbx15
T-box 15
chr13_-_35760969 0.33 ENSDART00000127476
erlec1
endoplasmic reticulum lectin 1
chr2_+_58008980 0.32 ENSDART00000171264
si:ch211-155e24.3
si:ch211-155e24.3
chr24_+_4373355 0.30 ENSDART00000179062
ENSDART00000093256
ENSDART00000138943
ccny
cyclin Y
chr2_+_2772447 0.30 ENSDART00000124882
thoc1
THO complex 1
chr15_-_25365319 0.29 ENSDART00000152651
cluha
clustered mitochondria (cluA/CLU1) homolog a
chr13_-_35761266 0.27 ENSDART00000190217
erlec1
endoplasmic reticulum lectin 1
chr21_-_33126697 0.27 ENSDART00000189293
ENSDART00000084559
CU019662.1

chr16_+_53489676 0.27 ENSDART00000074653
grinab
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1b (glutamate binding)
chr10_-_41400049 0.26 ENSDART00000009838
gpat4
glycerol-3-phosphate acyltransferase 4
chr1_+_9199031 0.26 ENSDART00000092058
ENSDART00000182771
chtf18
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
chr1_+_39865748 0.25 ENSDART00000131954
ENSDART00000130270
irf2a
interferon regulatory factor 2a
chr8_-_6918721 0.24 ENSDART00000014915
asb6
ankyrin repeat and SOCS box containing 6
chr5_-_24124118 0.24 ENSDART00000051550
capga
capping protein (actin filament), gelsolin-like a
chr8_-_45430817 0.24 ENSDART00000150067
ENSDART00000112394
ywhabb
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b
chr1_-_46505310 0.23 ENSDART00000178072
si:busm1-105l16.2
si:busm1-105l16.2
chr1_-_494280 0.22 ENSDART00000144406
ercc5
excision repair cross-complementation group 5
chr7_+_29962559 0.22 ENSDART00000075538
fbxo22
F-box protein 22
chr14_+_49251331 0.22 ENSDART00000148882
anxa6
annexin A6
chr14_+_52408619 0.22 ENSDART00000163856
noa1
nitric oxide associated 1
chr5_-_50084310 0.21 ENSDART00000074599
ENSDART00000189970
fam172a
family with sequence similarity 172, member A
chr22_+_9523479 0.21 ENSDART00000189473
ENSDART00000143953
strip1
striatin interacting protein 1
chr21_-_36453417 0.19 ENSDART00000018350
cnot8
CCR4-NOT transcription complex, subunit 8
chr15_-_31409013 0.19 ENSDART00000140456
or111-9
odorant receptor, family D, subfamily 111, member 9
chr16_+_12730311 0.18 ENSDART00000162030
ENSDART00000124544
epn1
epsin 1
chr7_+_26545502 0.17 ENSDART00000140528
tnk1
tyrosine kinase, non-receptor, 1
chr21_+_37513058 0.17 ENSDART00000141096
amot
angiomotin
chr8_-_6918290 0.16 ENSDART00000138259
ENSDART00000142496
asb6
ankyrin repeat and SOCS box containing 6
chr9_-_7287375 0.16 ENSDART00000128352
mitd1
MIT, microtubule interacting and transport, domain containing 1
chr5_+_872299 0.16 ENSDART00000130042
fubp3
far upstream element (FUSE) binding protein 3
chr20_+_46172649 0.15 ENSDART00000111317
taar13e
trace amine associated receptor 13e
chr2_+_54389750 0.14 ENSDART00000189236
rab12
RAB12, member RAS oncogene family
chr16_+_33930864 0.14 ENSDART00000125945
snip1
Smad nuclear interacting protein
chr4_+_29773917 0.13 ENSDART00000170798
BX530097.1

chr20_-_1439256 0.13 ENSDART00000002928
themis
thymocyte selection associated
chr19_+_17386393 0.12 ENSDART00000034837
rpl15
ribosomal protein L15
chr7_-_58826164 0.12 ENSDART00000171095
sox32
SRY (sex determining region Y)-box 32
chr14_+_38878482 0.12 ENSDART00000043317
timm8a
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr11_-_6868474 0.12 ENSDART00000168372
lsm4
LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
chr23_+_20644511 0.11 ENSDART00000133131
uba1
ubiquitin-like modifier activating enzyme 1
chr2_+_24317465 0.11 ENSDART00000139339
ENSDART00000136284
mrpl34
mitochondrial ribosomal protein L34
chr21_-_22928214 0.10 ENSDART00000182760
dub
duboraya
chr19_+_348729 0.10 ENSDART00000114284
mcl1a
MCL1, BCL2 family apoptosis regulator a
chr9_-_37637179 0.10 ENSDART00000188143
sema5ba
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Ba
chr3_+_36972298 0.10 ENSDART00000150917
si:ch211-18i17.2
si:ch211-18i17.2
chr16_+_54829574 0.08 ENSDART00000148392
pabpc1a
poly(A) binding protein, cytoplasmic 1a
chr3_-_35554809 0.08 ENSDART00000010944
dctn5
dynactin 5
chr7_-_46019756 0.06 ENSDART00000162583
zgc:162297
zgc:162297
chr22_+_22260210 0.06 ENSDART00000017755
ubxn6
UBX domain protein 6
chr6_-_19381993 0.06 ENSDART00000164114
grb2a
growth factor receptor-bound protein 2a
chr25_+_469855 0.05 ENSDART00000104717
rsl24d1
ribosomal L24 domain containing 1
chr2_+_37134281 0.05 ENSDART00000020135
pex19
peroxisomal biogenesis factor 19
chr1_+_12049229 0.05 ENSDART00000103403
ENSDART00000137697
saraf
store-operated calcium entry-associated regulatory factor
chr13_-_5978433 0.04 ENSDART00000102555
actr2b
ARP2 actin related protein 2b homolog
chr5_-_38777852 0.02 ENSDART00000131603
si:dkey-58f10.4
si:dkey-58f10.4
chr25_-_37338048 0.02 ENSDART00000073439
trim44
tripartite motif containing 44
chr9_-_21067673 0.01 ENSDART00000180257
tbx15
T-box 15
chr2_-_19520324 0.00 ENSDART00000079877
pimr52
Pim proto-oncogene, serine/threonine kinase, related 52

Network of associatons between targets according to the STRING database.

First level regulatory network of etv7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0034421 post-translational protein acetylation(GO:0034421)
0.5 1.5 GO:0000212 meiotic spindle organization(GO:0000212)
0.4 1.1 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.3 1.2 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.2 2.1 GO:0007220 Notch receptor processing(GO:0007220)
0.2 1.0 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.2 1.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 0.8 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2 1.2 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.2 0.7 GO:0034969 histone arginine methylation(GO:0034969)
0.2 0.5 GO:0036363 transforming growth factor beta activation(GO:0036363) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635)
0.2 2.8 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 0.7 GO:0031053 primary miRNA processing(GO:0031053)
0.1 0.7 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.7 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 1.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.5 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 0.8 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.6 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.7 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 0.7 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.7 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 0.5 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.7 GO:0016576 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.2 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 0.7 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.4 GO:0035475 angioblast cell migration involved in selective angioblast sprouting(GO:0035475)
0.1 0.6 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.1 0.2 GO:0001778 plasma membrane repair(GO:0001778) chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
0.1 0.4 GO:0036372 opsin transport(GO:0036372)
0.1 0.4 GO:2001032 positive regulation of double-strand break repair via homologous recombination(GO:1905168) regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.1 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.6 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 5.2 GO:0007283 spermatogenesis(GO:0007283)
0.0 0.7 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 1.1 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.6 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.4 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.0 0.1 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.0 1.1 GO:0006270 DNA replication initiation(GO:0006270)
0.0 1.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.9 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.2 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 1.2 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.4 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.3 GO:1901655 cellular response to ketone(GO:1901655)
0.0 0.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 2.1 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.0 0.1 GO:0003262 endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262)
0.0 1.1 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.0 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.6 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.1 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 1.2 GO:0042552 myelination(GO:0042552)
0.0 0.1 GO:0050975 sensory perception of touch(GO:0050975)
0.0 0.0 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 1.0 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.0 1.2 GO:0006413 translational initiation(GO:0006413)
0.0 1.5 GO:0006913 nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169)
0.0 0.6 GO:0045766 positive regulation of angiogenesis(GO:0045766)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.4 1.2 GO:0043614 multi-eIF complex(GO:0043614)
0.3 1.3 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.3 2.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.3 1.5 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 1.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 0.7 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.6 GO:0034657 GID complex(GO:0034657)
0.1 1.5 GO:0071564 npBAF complex(GO:0071564)
0.1 1.0 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.4 GO:0005879 axonemal microtubule(GO:0005879)
0.1 1.8 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 0.7 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 1.0 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 1.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.3 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 1.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 3.5 GO:0005730 nucleolus(GO:0005730)
0.0 1.2 GO:0005681 spliceosomal complex(GO:0005681)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.2 0.7 GO:0043621 protein self-association(GO:0043621)
0.2 1.5 GO:0035173 histone kinase activity(GO:0035173)
0.2 1.0 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.2 2.4 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 0.7 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.1 0.4 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.1 1.0 GO:0008506 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.6 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.5 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 0.3 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 0.4 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 1.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.4 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.4 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.2 GO:0035197 siRNA binding(GO:0035197)
0.0 2.1 GO:0043022 ribosome binding(GO:0043022)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0043142 DNA clamp loader activity(GO:0003689) single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) protein-DNA loading ATPase activity(GO:0033170) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)
0.0 0.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.4 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 1.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.0 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 2.7 GO:0042393 histone binding(GO:0042393)
0.0 1.9 GO:0004386 helicase activity(GO:0004386)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 1.5 PID AURORA A PATHWAY Aurora A signaling
0.0 1.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.2 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.1 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 1.1 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 2.1 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 1.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.2 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 2.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.5 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 1.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.0 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism