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PRJEB1986: zebrafish developmental stages transcriptome

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Results for eve1+evx1

Z-value: 0.86

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Transcription factors associated with eve1+evx1

Gene Symbol Gene ID Gene Info
eve1
ENSDARG00000056012 even-skipped-like1
evx1
ENSDARG00000099365 even-skipped homeobox 1
evx1
ENSDARG00000100087 even-skipped homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
evx1dr11_v1_chr19_-_19871211_19871211-0.787.8e-05Click!
eve1dr11_v1_chr3_-_23643751_23643830-0.493.4e-02Click!

Activity profile of eve1+evx1 motif

Sorted Z-values of eve1+evx1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_11385155 4.26 ENSDART00000064214
plac8.1
placenta-specific 8, tandem duplicate 1
chr19_+_40856534 3.83 ENSDART00000051950
gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr18_+_1837668 3.68 ENSDART00000164210
CABZ01079192.1

chr19_+_40856807 3.38 ENSDART00000139083
gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr3_-_31079186 2.84 ENSDART00000145636
ENSDART00000140569
ELOB (1 of many)
elob
elongin B
elongin B
chr8_-_21372446 2.46 ENSDART00000061481
ENSDART00000079293
ela2l
elastase 2 like
chr4_+_11384891 2.35 ENSDART00000092381
ENSDART00000186577
ENSDART00000191054
ENSDART00000191584
pcloa
piccolo presynaptic cytomatrix protein a
chr16_-_54455573 2.22 ENSDART00000075275
pklr
pyruvate kinase L/R
chr23_+_40460333 2.05 ENSDART00000184658
soga3b
SOGA family member 3b
chr8_+_53423408 2.02 ENSDART00000164792
cacna1db
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr21_-_27185915 1.97 ENSDART00000135052
slc8a4a
solute carrier family 8 (sodium/calcium exchanger), member 4a
chr6_-_55585423 1.91 ENSDART00000157129
slc12a5a
solute carrier family 12 (potassium/chloride transporter), member 5a
chr9_-_6372535 1.85 ENSDART00000149189
ecrg4a
esophageal cancer related gene 4a
chr25_-_25384045 1.75 ENSDART00000150631
zgc:123278
zgc:123278
chr18_+_9615147 1.71 ENSDART00000160284
pclob
piccolo presynaptic cytomatrix protein b
chr23_-_19230627 1.69 ENSDART00000007122
guca1b
guanylate cyclase activator 1B
chr20_-_40755614 1.65 ENSDART00000061247
cx32.3
connexin 32.3
chr10_+_25726694 1.58 ENSDART00000140308
ugt5d1
UDP glucuronosyltransferase 5 family, polypeptide D1
chr2_-_1443692 1.56 ENSDART00000004533
rpe65a
retinal pigment epithelium-specific protein 65a
chr11_+_38280454 1.52 ENSDART00000171496
CDK18
si:dkey-166c18.1
chr1_-_47071979 1.48 ENSDART00000160817
itsn1
intersectin 1 (SH3 domain protein)
chr19_-_657439 1.42 ENSDART00000167100
slc6a18
solute carrier family 6 (neutral amino acid transporter), member 18
chr4_-_67969695 1.40 ENSDART00000190016
si:ch211-223k15.1
si:ch211-223k15.1
chr1_+_17676745 1.36 ENSDART00000030665
slc25a4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr5_+_64732270 1.33 ENSDART00000134241
olfm1a
olfactomedin 1a
chr10_+_3049636 1.27 ENSDART00000081794
ENSDART00000183167
ENSDART00000191634
ENSDART00000183514
rasgrf2a
Ras protein-specific guanine nucleotide-releasing factor 2a
chr25_+_3327071 1.26 ENSDART00000136131
ENSDART00000133243
ldhbb
lactate dehydrogenase Bb
chr18_+_11506561 1.24 ENSDART00000121647
PRMT8
protein arginine methyltransferase 8
chr5_+_64732036 1.21 ENSDART00000073950
olfm1a
olfactomedin 1a
chr24_-_39518599 1.20 ENSDART00000145606
ENSDART00000031486
lyrm1
LYR motif containing 1
chr15_+_9053059 1.17 ENSDART00000012039
ppm1na
protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative)
chr15_+_47418565 1.17 ENSDART00000155709
clpb
ClpB homolog, mitochondrial AAA ATPase chaperonin
chr21_+_30355767 1.17 ENSDART00000189948
CR749164.1

chr3_+_1005059 1.16 ENSDART00000132460
zgc:172051
zgc:172051
chr13_+_38814521 1.10 ENSDART00000110976
col19a1
collagen, type XIX, alpha 1
chr17_-_23616626 1.09 ENSDART00000104730
ifit14
interferon-induced protein with tetratricopeptide repeats 14
chr21_+_1381276 1.07 ENSDART00000192907
TCF4
transcription factor 4
chr2_-_57076687 1.04 ENSDART00000161523
slc25a42
solute carrier family 25, member 42
chr23_+_33963619 1.03 ENSDART00000140666
ENSDART00000084792
plpbp
pyridoxal phosphate binding protein
chr23_-_44219902 1.03 ENSDART00000185874
zgc:158659
zgc:158659
chr22_+_17205608 1.00 ENSDART00000181267
rab3b
RAB3B, member RAS oncogene family
chr1_+_11977426 0.99 ENSDART00000103399
tspan5b
tetraspanin 5b
chr2_+_31492662 0.99 ENSDART00000123495
cacnb2b
calcium channel, voltage-dependent, beta 2b
chr17_-_28198099 0.96 ENSDART00000156143
htr1d
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr21_-_3770636 0.95 ENSDART00000053596
scamp1
secretory carrier membrane protein 1
chr16_-_2414063 0.94 ENSDART00000073621
zgc:152945
zgc:152945
chr20_-_46362606 0.92 ENSDART00000153087
bmf2
BCL2 modifying factor 2
chr18_-_43884044 0.90 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr5_+_27137473 0.84 ENSDART00000181833
unc5db
unc-5 netrin receptor Db
chr19_-_205104 0.84 ENSDART00000011890
zbtb22a
zinc finger and BTB domain containing 22a
chr2_-_32825917 0.84 ENSDART00000180409
prpf4ba
pre-mRNA processing factor 4Ba
chr15_-_34785594 0.84 ENSDART00000154256
gabbr1a
gamma-aminobutyric acid (GABA) B receptor, 1a
chr10_+_41765944 0.84 ENSDART00000171484
rnf34b
ring finger protein 34b
chr9_+_17983463 0.84 ENSDART00000182150
akap11
A kinase (PRKA) anchor protein 11
chr2_-_16380283 0.83 ENSDART00000149992
si:dkey-231j24.3
si:dkey-231j24.3
chr24_-_1341543 0.83 ENSDART00000169341
nrp1a
neuropilin 1a
chr19_+_5543072 0.83 ENSDART00000082080
jupb
junction plakoglobin b
chr5_-_30615901 0.80 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr23_+_26946744 0.79 ENSDART00000115141
cacnb3b
calcium channel, voltage-dependent, beta 3b
chr23_+_4646194 0.79 ENSDART00000092344
LO017700.1

chr21_+_11244068 0.78 ENSDART00000163432
arid6
AT-rich interaction domain 6
chr11_+_45323455 0.77 ENSDART00000189249
mafgb
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb
chr7_-_24046999 0.77 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dhrs4
dehydrogenase/reductase (SDR family) member 4
chr16_+_5774977 0.77 ENSDART00000134202
ccka
cholecystokinin a
chr10_+_21867307 0.75 ENSDART00000126629
cbln17
cerebellin 17
chr21_-_18993110 0.74 ENSDART00000144086
si:ch211-222n4.6
si:ch211-222n4.6
chr6_+_24398907 0.73 ENSDART00000167482
tgfbr3
transforming growth factor, beta receptor III
chr19_+_712127 0.73 ENSDART00000093281
ENSDART00000180002
ENSDART00000146050
fhod3a
formin homology 2 domain containing 3a
chr16_+_17389116 0.73 ENSDART00000103750
ENSDART00000173448
fam131bb
family with sequence similarity 131, member Bb
chr21_-_3853204 0.72 ENSDART00000188829
st6galnac4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr2_-_32826108 0.72 ENSDART00000098834
prpf4ba
pre-mRNA processing factor 4Ba
chr2_-_11258547 0.69 ENSDART00000165803
ENSDART00000193817
slc44a5a
solute carrier family 44, member 5a
chr4_+_12612723 0.69 ENSDART00000133767
lmo3
LIM domain only 3
chr12_-_32426685 0.69 ENSDART00000105574
enpp7.2
ectonucleotide pyrophosphatase/phosphodiesterase 7, tandem duplicate 2
chr14_-_8625845 0.67 ENSDART00000054760
zgc:162144
zgc:162144
chr6_+_9870192 0.67 ENSDART00000150894
MPP4 (1 of many)
si:ch211-222n4.6
chr3_-_34084387 0.66 ENSDART00000155365
ighv4-3
immunoglobulin heavy variable 4-3
chr18_+_28106139 0.66 ENSDART00000089615
kiaa1549lb
KIAA1549-like b
chr8_+_52503340 0.66 ENSDART00000168838
si:ch1073-392o20.1
si:ch1073-392o20.1
chr11_+_28476298 0.65 ENSDART00000122319
lrrc38b
leucine rich repeat containing 38b
chr6_+_41039166 0.65 ENSDART00000125659
entpd8
ectonucleoside triphosphate diphosphohydrolase 8
chr9_-_21918963 0.64 ENSDART00000090782
lmo7a
LIM domain 7a
chr11_+_36231248 0.63 ENSDART00000131104
GPR62 (1 of many)
si:ch211-213o11.11
chr1_-_10647484 0.63 ENSDART00000164541
ENSDART00000188958
ENSDART00000190904
si:dkey-31e10.1
si:dkey-31e10.1
chr20_+_22067337 0.62 ENSDART00000152636
clocka
clock circadian regulator a
chr4_-_49582108 0.62 ENSDART00000154999
si:dkey-159n16.2
si:dkey-159n16.2
chr1_+_16396870 0.61 ENSDART00000189245
ENSDART00000113266
micu3a
mitochondrial calcium uptake family, member 3a
chr23_-_33361425 0.59 ENSDART00000031638
slc48a1a
solute carrier family 48 (heme transporter), member 1a
chr6_-_6487876 0.56 ENSDART00000137642
cep170ab
centrosomal protein 170Ab
chr19_+_9033376 0.55 ENSDART00000192298
ENSDART00000052915
ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr8_-_30338872 0.53 ENSDART00000137583
dock8
dedicator of cytokinesis 8
chr24_+_36636208 0.53 ENSDART00000139211
si:ch73-334d15.4
si:ch73-334d15.4
chr5_+_19314574 0.51 ENSDART00000133247
rusc2
RUN and SH3 domain containing 2
chr1_-_9195629 0.51 ENSDART00000143587
ENSDART00000192174
ern2
endoplasmic reticulum to nucleus signaling 2
chr5_-_42904329 0.47 ENSDART00000112807
cxcl20
chemokine (C-X-C motif) ligand 20
chr1_-_46981134 0.46 ENSDART00000130607
pknox1.2
pbx/knotted 1 homeobox 1.2
chr21_-_5205617 0.46 ENSDART00000145554
ENSDART00000045284
rpl37
ribosomal protein L37
chr12_-_24060358 0.46 ENSDART00000050831
chac2
ChaC, cation transport regulator homolog 2 (E. coli)
chr18_+_50461981 0.45 ENSDART00000158761
CU896640.1

chr2_+_21229909 0.44 ENSDART00000046127
vipr1a
vasoactive intestinal peptide receptor 1a
chr15_-_22074315 0.44 ENSDART00000149830
drd2a
dopamine receptor D2a
chr8_-_21142550 0.43 ENSDART00000143192
ENSDART00000186820
ENSDART00000135938
cpt2
carnitine palmitoyltransferase 2
chr19_-_44054930 0.43 ENSDART00000151084
ENSDART00000150991
ENSDART00000005191
uqcrb
ubiquinol-cytochrome c reductase binding protein
chrM_+_12897 0.43 ENSDART00000093622
mt-nd5
NADH dehydrogenase 5, mitochondrial
chr1_+_51191049 0.41 ENSDART00000132244
ENSDART00000014970
ENSDART00000132141
btbd3a
BTB (POZ) domain containing 3a
chr5_+_38263240 0.41 ENSDART00000051231
gnb2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr16_-_36093776 0.41 ENSDART00000159134
OSCP1
organic solute carrier partner 1
chr16_-_25829779 0.40 ENSDART00000086301
irge4
immunity-related GTPase family, e4
chr3_+_54047342 0.40 ENSDART00000178486
olfm2a
olfactomedin 2a
chr6_+_515181 0.40 ENSDART00000171374
CACNA1I (1 of many)
si:ch73-379f7.5
chr18_-_1185772 0.40 ENSDART00000143245
nptnb
neuroplastin b
chr18_+_11970987 0.39 ENSDART00000144111
si:dkeyp-2c8.3
si:dkeyp-2c8.3
chr10_-_21955231 0.39 ENSDART00000183695
FO744833.2

chr3_-_8399774 0.38 ENSDART00000190238
ENSDART00000113140
ENSDART00000132949
rbfox3b
RNA binding fox-1 homolog 3b
chr24_-_41320037 0.37 ENSDART00000129058
rheb
Ras homolog, mTORC1 binding
chr6_+_39232245 0.36 ENSDART00000187351
b4galnt1b
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr7_-_64589920 0.35 ENSDART00000172619
ENSDART00000184113
CR387919.1

chr21_+_40292801 0.34 ENSDART00000174220
si:ch211-218m3.16
si:ch211-218m3.16
chr23_-_20051369 0.33 ENSDART00000049836
bgnb
biglycan b
chr7_+_30787903 0.32 ENSDART00000174000
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr14_+_45406299 0.31 ENSDART00000173142
ENSDART00000112377
map1lc3cl
microtubule-associated protein 1 light chain 3 gamma, like
chr3_+_32832538 0.31 ENSDART00000139410
cd2bp2
CD2 (cytoplasmic tail) binding protein 2
chr3_+_17537352 0.30 ENSDART00000104549
hcrt
hypocretin (orexin) neuropeptide precursor
chr22_-_37686966 0.30 ENSDART00000192217
htr2b
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr19_+_19241372 0.30 ENSDART00000184392
ENSDART00000165008
ptpn23b
protein tyrosine phosphatase, non-receptor type 23, b
chr15_+_22014029 0.30 ENSDART00000079504
ankk1
ankyrin repeat and kinase domain containing 1
chr23_-_24394719 0.30 ENSDART00000044918
epha2b
eph receptor A2 b
chr1_-_10647307 0.30 ENSDART00000103548
si:dkey-31e10.1
si:dkey-31e10.1
chr7_-_27685365 0.30 ENSDART00000188342
calca
calcitonin/calcitonin-related polypeptide, alpha
chr4_+_9400012 0.29 ENSDART00000191960
tmtc1
transmembrane and tetratricopeptide repeat containing 1
chr3_+_27786601 0.28 ENSDART00000086994
nat15
N-acetyltransferase 15 (GCN5-related, putative)
chr12_-_19007834 0.27 ENSDART00000153248
chadlb
chondroadherin-like b
chr11_-_44876005 0.26 ENSDART00000192006
opn6a
opsin 6, group member a
chr8_-_27656765 0.26 ENSDART00000078491
mov10b.2
Moloney leukemia virus 10b, tandem duplicate 2
chr15_-_23793641 0.26 ENSDART00000122891
tmem97
transmembrane protein 97
chr18_-_12052132 0.26 ENSDART00000074361
zgc:110789
zgc:110789
chr20_-_9462433 0.25 ENSDART00000152674
ENSDART00000040557
zgc:101840
zgc:101840
chr25_+_26923193 0.25 ENSDART00000187364
grm8b
glutamate receptor, metabotropic 8b
chr12_-_4408828 0.24 ENSDART00000152447
si:ch211-173d10.1
si:ch211-173d10.1
chr20_-_13722514 0.24 ENSDART00000152458
si:ch211-122h15.4
si:ch211-122h15.4
chr2_-_21819421 0.23 ENSDART00000121586
chd7
chromodomain helicase DNA binding protein 7
chr1_+_16397063 0.23 ENSDART00000159794
micu3a
mitochondrial calcium uptake family, member 3a
chr1_-_17715493 0.23 ENSDART00000133027
si:dkey-256e7.8
si:dkey-256e7.8
chr22_-_10121880 0.21 ENSDART00000002348
rdh5
retinol dehydrogenase 5 (11-cis/9-cis)
chr25_+_35891342 0.20 ENSDART00000147093
lsm14aa
LSM14A mRNA processing body assembly factor a
chr2_-_17235891 0.19 ENSDART00000144251
artnb
artemin b
chr11_-_45152702 0.19 ENSDART00000168066
afmid
arylformamidase
chr9_+_41156818 0.19 ENSDART00000105764
ENSDART00000147052
stat4
signal transducer and activator of transcription 4
chr3_+_18398876 0.18 ENSDART00000141100
ENSDART00000138107
rps2
ribosomal protein S2
chr16_-_21038015 0.18 ENSDART00000059239
snx10b
sorting nexin 10b
chr6_-_57655030 0.18 ENSDART00000155438
cbfa2t2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr8_-_24252933 0.17 ENSDART00000057624
zgc:110353
zgc:110353
chr14_+_924876 0.17 ENSDART00000183908
myoz3a
myozenin 3a
chr2_+_30464829 0.15 ENSDART00000181432
neto1
neuropilin (NRP) and tolloid (TLL)-like 1
chr5_+_26765275 0.14 ENSDART00000144169
si:ch211-102c2.8
si:ch211-102c2.8
chr21_+_34814444 0.14 ENSDART00000161816
wdr55
WD repeat domain 55
chr10_-_41664427 0.12 ENSDART00000150213
ggt1b
gamma-glutamyltransferase 1b
chr4_-_71912457 0.12 ENSDART00000179685
si:dkey-92c21.1
si:dkey-92c21.1
chr2_+_30465102 0.12 ENSDART00000188404
neto1
neuropilin (NRP) and tolloid (TLL)-like 1
chr16_+_11029762 0.10 ENSDART00000091183
erfl3
Ets2 repressor factor like 3
chr21_-_42831033 0.09 ENSDART00000160998
stk10
serine/threonine kinase 10
chr22_-_881725 0.08 ENSDART00000035514
cept1b
choline/ethanolamine phosphotransferase 1b
chr20_+_41021054 0.08 ENSDART00000146052
man1a1
mannosidase, alpha, class 1A, member 1
chr11_-_29768054 0.08 ENSDART00000079117
plekha3
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
chr2_-_26720854 0.08 ENSDART00000148110
si:dkey-181m9.8
si:dkey-181m9.8
chr15_+_29662401 0.07 ENSDART00000135540
nrip1a
nuclear receptor interacting protein 1a
chr22_+_20427170 0.07 ENSDART00000136744
foxq2
forkhead box Q2
chr17_-_23446760 0.06 ENSDART00000104715
pcgf5a
polycomb group ring finger 5a
chr9_-_54361357 0.06 ENSDART00000149813
rad50
RAD50 homolog, double strand break repair protein
chr13_+_33117528 0.06 ENSDART00000085719
si:ch211-10a23.2
si:ch211-10a23.2
chr1_+_55758257 0.06 ENSDART00000139312
tecrb
trans-2,3-enoyl-CoA reductase b
chr15_+_31481939 0.05 ENSDART00000134306
or102-5
odorant receptor, family C, subfamily 102, member 5
chr15_+_5360407 0.05 ENSDART00000110420
or112-1
odorant receptor, family A, subfamily 112, member 1
chr16_-_29458806 0.05 ENSDART00000047931
lingo4b
leucine rich repeat and Ig domain containing 4b
chr3_+_13624815 0.03 ENSDART00000161451
pglyrp6
peptidoglycan recognition protein 6
chr6_-_40352215 0.02 ENSDART00000103992
ttll3
tubulin tyrosine ligase-like family, member 3
chr2_-_15324837 0.02 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr24_+_16547035 0.00 ENSDART00000164319
sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A

Network of associatons between targets according to the STRING database.

First level regulatory network of eve1+evx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0070314 G1 to G0 transition(GO:0070314)
0.4 4.1 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.4 1.6 GO:0016123 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.4 1.1 GO:0044038 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.3 1.4 GO:0051503 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.3 2.5 GO:0061075 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.2 0.8 GO:0002164 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.2 0.8 GO:0002159 desmosome assembly(GO:0002159)
0.2 2.0 GO:0042044 fluid transport(GO:0042044)
0.1 1.1 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.8 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.8 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.4 GO:0015990 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.1 1.2 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.5 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 1.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.8 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.3 GO:0042755 eating behavior(GO:0042755)
0.1 2.2 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 0.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.6 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 1.3 GO:0050795 regulation of behavior(GO:0050795)
0.1 2.8 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1 0.6 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 0.3 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 1.2 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.8 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.7 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 1.4 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.2 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.9 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.7 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.5 GO:0036230 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 2.2 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 1.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.5 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.2 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 1.0 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.0 0.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 2.0 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.7 GO:1903844 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0 0.4 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0060465 pharynx development(GO:0060465)
0.0 0.6 GO:0009648 photoperiodism(GO:0009648)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.8 GO:0007586 digestion(GO:0007586)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.4 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 1.1 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.0 0.5 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.3 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.0 GO:0016045 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.8 GO:0030891 VCB complex(GO:0030891)
0.4 7.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.4 4.1 GO:0098982 GABA-ergic synapse(GO:0098982)
0.2 0.5 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.6 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 0.8 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 1.0 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.6 GO:0016586 RSC complex(GO:0016586)
0.1 0.8 GO:1990246 uniplex complex(GO:1990246)
0.1 3.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.8 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.0 GO:0042383 sarcolemma(GO:0042383)
0.0 1.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 1.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.4 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.7 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 3.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.7 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0050251 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.4 2.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.3 1.0 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.3 7.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.3 1.4 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.2 4.1 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.2 1.7 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.2 1.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 2.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.7 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.5 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.1 0.5 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.8 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 3.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.3 GO:0031716 calcitonin receptor binding(GO:0031716)
0.1 0.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.6 GO:0070888 E-box binding(GO:0070888)
0.1 0.3 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.1 0.8 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.9 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 0.4 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.6 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.8 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.2 GO:0004061 arylformamidase activity(GO:0004061)
0.1 0.4 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.0 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.7 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.4 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.3 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 1.2 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 1.2 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 1.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.8 GO:0051018 protein kinase A binding(GO:0051018)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.0 0.1 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.0 1.0 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.7 GO:0044325 ion channel binding(GO:0044325)
0.0 0.0 GO:0016019 peptidoglycan receptor activity(GO:0016019)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.1 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 2.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 1.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 2.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 0.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.4 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 1.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME AMYLOIDS Genes involved in Amyloids