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PRJEB1986: zebrafish developmental stages transcriptome

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Results for foxb1a

Z-value: 0.59

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Transcription factors associated with foxb1a

Gene Symbol Gene ID Gene Info
foxb1a
ENSDARG00000089042 forkhead box B1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxb1adr11_v1_chr25_-_34156152_34156152-0.752.0e-04Click!

Activity profile of foxb1a motif

Sorted Z-values of foxb1a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_39386982 2.29 ENSDART00000146702
tnni2b.2
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr21_+_40092301 2.19 ENSDART00000145150
serpinf2a
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a
chr6_-_35446110 2.12 ENSDART00000058773
rgs16
regulator of G protein signaling 16
chr13_+_23988442 1.85 ENSDART00000010918
agt
angiotensinogen
chr14_+_15155684 1.69 ENSDART00000167966
zgc:158852
zgc:158852
chr3_+_19207176 1.46 ENSDART00000087803
rln3a
relaxin 3a
chr16_-_43025885 1.38 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
si:dkey-7j14.5
chr2_+_6885852 1.37 ENSDART00000016607
rgs5b
regulator of G protein signaling 5b
chr4_+_7841627 1.24 ENSDART00000037997
ucmaa
upper zone of growth plate and cartilage matrix associated a
chr23_+_21966447 1.20 ENSDART00000189378
lactbl1a
lactamase, beta-like 1a
chr18_-_5781922 1.14 ENSDART00000128722
RGS9BP
si:ch73-167i17.6
chr9_-_9992697 1.09 ENSDART00000123415
ugt1ab
UDP glucuronosyltransferase 1 family a, b
chr23_+_31405497 1.07 ENSDART00000053546
sh3bgrl2
SH3 domain binding glutamate-rich protein like 2
chr16_-_12173554 1.04 ENSDART00000110567
ENSDART00000155935
clstn3
calsyntenin 3
chr23_-_27633730 0.90 ENSDART00000103639
arf3a
ADP-ribosylation factor 3a
chr4_+_12013043 0.90 ENSDART00000130692
cry1aa
cryptochrome circadian clock 1aa
chr9_-_44905867 0.89 ENSDART00000138316
ENSDART00000131252
ENSDART00000179383
ENSDART00000159337
zgc:66484
zgc:66484
chr6_-_51101834 0.89 ENSDART00000092493
ptprt
protein tyrosine phosphatase, receptor type, t
chr4_+_12013642 0.85 ENSDART00000067281
cry1aa
cryptochrome circadian clock 1aa
chr19_-_31522625 0.83 ENSDART00000158438
ENSDART00000035049
necab1
N-terminal EF-hand calcium binding protein 1
chr17_-_20287530 0.77 ENSDART00000078703
ENSDART00000191289
add3b
adducin 3 (gamma) b
chr2_-_43168292 0.76 ENSDART00000132588
crema
cAMP responsive element modulator a
chr11_-_29082175 0.75 ENSDART00000123245
igsf21a
immunoglobin superfamily, member 21a
chr4_+_8797197 0.73 ENSDART00000158671
sult4a1
sulfotransferase family 4A, member 1
chr22_+_20195280 0.67 ENSDART00000088603
ENSDART00000135692
si:dkey-110c1.7
si:dkey-110c1.7
chr16_+_46492994 0.67 ENSDART00000134734
rpz5
rapunzel 5
chr3_-_13146631 0.65 ENSDART00000172460
prkar1b
protein kinase, cAMP-dependent, regulatory, type I, beta
chr14_-_4120636 0.64 ENSDART00000059230
irf2
interferon regulatory factor 2
chr16_-_12173399 0.64 ENSDART00000142574
clstn3
calsyntenin 3
chr15_+_14856307 0.63 ENSDART00000167213
diabloa
diablo, IAP-binding mitochondrial protein a
chr5_-_52243424 0.63 ENSDART00000159078
erap2
endoplasmic reticulum aminopeptidase 2
chr1_+_25801648 0.63 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr4_-_4834617 0.59 ENSDART00000141539
coa6
cytochrome c oxidase assembly factor 6
chr12_+_48480632 0.58 ENSDART00000158157
arhgap44
Rho GTPase activating protein 44
chr23_+_44881020 0.56 ENSDART00000149355
si:ch73-361h17.1
si:ch73-361h17.1
chr5_-_13086616 0.54 ENSDART00000051664
ypel1
yippee-like 1
chr8_-_14184423 0.54 ENSDART00000063817
ndufb11
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11
chr9_-_46072805 0.51 ENSDART00000169682
hdac4
histone deacetylase 4
chr19_+_14573998 0.51 ENSDART00000022076
fam46bb
family with sequence similarity 46, member Bb
chr11_+_30162407 0.50 ENSDART00000190333
ENSDART00000127502
cdkl5
cyclin-dependent kinase-like 5
chr3_+_34877066 0.49 ENSDART00000161963
itga3a
integrin, alpha 3a
chr21_+_27416284 0.48 ENSDART00000077593
ENSDART00000108763
cfb
complement factor B
chr24_+_15897717 0.48 ENSDART00000105956
neto1l
neuropilin (NRP) and tolloid (TLL)-like 1, like
chr9_+_19489514 0.48 ENSDART00000152032
ENSDART00000114256
ENSDART00000190572
ENSDART00000147571
ENSDART00000151918
ENSDART00000152034
si:ch211-140m22.7
si:ch211-140m22.7
chr12_-_28537615 0.47 ENSDART00000067762
MYO1D
si:ch211-94l19.4
chr17_+_24006792 0.46 ENSDART00000122415
si:ch211-63b16.4
si:ch211-63b16.4
chr16_-_43356018 0.45 ENSDART00000181683
FO704821.1

chr5_-_24000211 0.45 ENSDART00000188865
map7d2a
MAP7 domain containing 2a
chr4_-_4834347 0.45 ENSDART00000141803
coa6
cytochrome c oxidase assembly factor 6
chr6_-_9565526 0.44 ENSDART00000151470
map3k2
mitogen-activated protein kinase kinase kinase 2
chr17_-_14613711 0.44 ENSDART00000157345
sdsl
serine dehydratase-like
chr25_+_21178033 0.44 ENSDART00000041169
erc1a
ELKS/RAB6-interacting/CAST family member 1a
chr14_-_17576391 0.43 ENSDART00000161355
ENSDART00000168959
rnf4
ring finger protein 4
chr21_-_11856143 0.42 ENSDART00000151204
ube2r2
ubiquitin-conjugating enzyme E2R 2
chr10_+_8847033 0.42 ENSDART00000140894
itga2.1
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 1
chr6_+_40671336 0.41 ENSDART00000111639
ENSDART00000186617
rereb
arginine-glutamic acid dipeptide (RE) repeats b
chr7_-_32599669 0.41 ENSDART00000173752
kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr24_-_21620316 0.41 ENSDART00000112670
usp12a
ubiquitin specific peptidase 12a
chr1_-_49947290 0.40 ENSDART00000141476
sgms2
sphingomyelin synthase 2
chr6_-_51386656 0.39 ENSDART00000154732
ENSDART00000177990
ENSDART00000184928
ENSDART00000180197
ptprt
protein tyrosine phosphatase, receptor type, t
chr1_+_16073887 0.37 ENSDART00000160270
tusc3
tumor suppressor candidate 3
chr23_-_33750135 0.37 ENSDART00000187641
bin2a
bridging integrator 2a
chr11_+_6819050 0.37 ENSDART00000104289
rab3ab
RAB3A, member RAS oncogene family, b
chr23_-_33750307 0.37 ENSDART00000162772
bin2a
bridging integrator 2a
chr11_+_6295370 0.35 ENSDART00000139882
ranbp3a
RAN binding protein 3a
chr19_+_30990815 0.35 ENSDART00000134645
sync
syncoilin, intermediate filament protein
chr18_-_6803424 0.35 ENSDART00000142647
si:dkey-266m15.5
si:dkey-266m15.5
chr25_+_3677650 0.35 ENSDART00000154348
prnprs3
prion protein, related sequence 3
chr5_-_19494048 0.34 ENSDART00000098795
mmab
methylmalonic aciduria (cobalamin deficiency) cblB type
chr18_+_19974289 0.34 ENSDART00000090334
ENSDART00000192982
skor1b
SKI family transcriptional corepressor 1b
chr25_+_28253844 0.33 ENSDART00000151891
cadps2
Ca++-dependent secretion activator 2
chr7_-_31941330 0.33 ENSDART00000144682
bdnf
brain-derived neurotrophic factor
chr16_-_12784373 0.33 ENSDART00000080396
foxj2
forkhead box J2
chr16_-_25233515 0.33 ENSDART00000058943
zgc:110182
zgc:110182
chr9_+_13986427 0.32 ENSDART00000147200
cd28
CD28 molecule
chr16_-_34477805 0.31 ENSDART00000136546
serinc2l
serine incorporator 2, like
chr2_+_30463825 0.31 ENSDART00000092356
neto1
neuropilin (NRP) and tolloid (TLL)-like 1
chr7_+_46252993 0.31 ENSDART00000167149
znf536
zinc finger protein 536
chr20_+_6756247 0.30 ENSDART00000167344
igfbp3
insulin-like growth factor binding protein 3
chr7_-_31941670 0.29 ENSDART00000180929
ENSDART00000075389
bdnf
brain-derived neurotrophic factor
chr13_-_21701323 0.28 ENSDART00000164112
si:dkey-191g9.7
si:dkey-191g9.7
chr9_+_22632126 0.27 ENSDART00000139434
etv5a
ets variant 5a
chr3_-_1364946 0.27 ENSDART00000159328
FP236551.1

chr3_-_60142530 0.26 ENSDART00000153247
si:ch211-120g10.1
si:ch211-120g10.1
chr1_-_37383741 0.26 ENSDART00000193155
ENSDART00000191887
ENSDART00000189077
scpp1
secretory calcium-binding phosphoprotein 1
chr19_-_19025998 0.25 ENSDART00000186156
ENSDART00000163359
ENSDART00000167951
dync1li1
dynein, cytoplasmic 1, light intermediate chain 1
chr1_-_37383539 0.25 ENSDART00000127579
scpp1
secretory calcium-binding phosphoprotein 1
chr6_+_13730522 0.25 ENSDART00000153524
wnt6a
wingless-type MMTV integration site family, member 6a
chr24_+_19210001 0.25 ENSDART00000179373
ENSDART00000139299
zgc:162928
zgc:162928
chr13_+_21601149 0.24 ENSDART00000179369
sh2d4ba
SH2 domain containing 4Ba
chr24_-_22756508 0.24 ENSDART00000035409
ENSDART00000146247
zc2hc1a
zinc finger, C2HC-type containing 1A
chr3_-_49138004 0.23 ENSDART00000167173
gipc1
GIPC PDZ domain containing family, member 1
chr15_+_44206698 0.23 ENSDART00000186996
CU929391.1

chr5_-_34993242 0.22 ENSDART00000134516
ENSDART00000051295
btf3
basic transcription factor 3
chr5_-_67757188 0.22 ENSDART00000167168
b4galt4
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr5_-_38384289 0.22 ENSDART00000135260
mink1
misshapen-like kinase 1
chr6_-_3998199 0.21 ENSDART00000059212
unc50
unc-50 homolog (C. elegans)
chr8_-_3963100 0.21 ENSDART00000139023
mtmr3
myotubularin related protein 3
chr16_+_11724230 0.21 ENSDART00000060266
ceacam1
carcinoembryonic antigen-related cell adhesion molecule 1
chr7_+_21887787 0.20 ENSDART00000162252
pop7
POP7 homolog, ribonuclease P/MRP subunit
chr11_+_8170948 0.20 ENSDART00000112127
ENSDART00000186267
dnase2b
deoxyribonuclease II beta
chr22_+_26798853 0.19 ENSDART00000087576
ENSDART00000179780
slx4
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
chr2_+_3881000 0.18 ENSDART00000081897
mpp7b
membrane protein, palmitoylated 7b (MAGUK p55 subfamily member 7)
chr24_-_25574967 0.17 ENSDART00000189828
cnksr2a
connector enhancer of kinase suppressor of Ras 2a
chr21_-_18824434 0.16 ENSDART00000156333
si:dkey-112m2.1
si:dkey-112m2.1
chr2_-_5399437 0.16 ENSDART00000132411
si:ch1073-184j22.2
si:ch1073-184j22.2
chr7_+_9308625 0.15 ENSDART00000084598
selenos
selenoprotein S
chr15_-_8856391 0.15 ENSDART00000008273
rab4b
RAB4B, member RAS oncogene family
chr16_-_36748374 0.15 ENSDART00000133310
pik3r4
phosphoinositide-3-kinase, regulatory subunit 4
chr20_-_39103119 0.14 ENSDART00000143379
rcan2
regulator of calcineurin 2
chr14_-_24110707 0.14 ENSDART00000133522
ENSDART00000123152
cpeb4a
cytoplasmic polyadenylation element binding protein 4a
chr12_-_19151708 0.13 ENSDART00000057124
tefa
thyrotrophic embryonic factor a
chr5_-_4931266 0.13 ENSDART00000067600
zbtb43
zinc finger and BTB domain containing 43
chr20_-_20533865 0.13 ENSDART00000125039
six6b
SIX homeobox 6b
chr2_+_24786765 0.13 ENSDART00000141030
pde4ca
phosphodiesterase 4C, cAMP-specific a
chr13_+_21600946 0.13 ENSDART00000144045
sh2d4ba
SH2 domain containing 4Ba
chr15_+_36445350 0.13 ENSDART00000154552
si:dkey-262k9.2
si:dkey-262k9.2
chr14_-_9982603 0.12 ENSDART00000054687
il1rapl2
interleukin 1 receptor accessory protein-like 2
chr21_-_21781158 0.12 ENSDART00000113734
chrdl2
chordin-like 2
chr4_+_77907740 0.12 ENSDART00000172216
si:zfos-2131b9.2
si:zfos-2131b9.2
chr20_-_52928541 0.11 ENSDART00000162812
fdft1
farnesyl-diphosphate farnesyltransferase 1
chr3_+_1724941 0.10 ENSDART00000193402
BX321875.2

chr11_+_26403334 0.10 ENSDART00000171781
fer1l4
fer-1-like family member 4
chr10_-_8129456 0.10 ENSDART00000180916
ndufa9b
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9b
chr24_-_37484123 0.09 ENSDART00000111623
cluap1
clusterin associated protein 1
chr19_+_390298 0.09 ENSDART00000136361
sema6d
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr18_-_39702327 0.08 ENSDART00000149158
dmxl2
Dmx-like 2
chr21_-_11855828 0.08 ENSDART00000081666
ube2r2
ubiquitin-conjugating enzyme E2R 2
chr8_+_24740013 0.07 ENSDART00000126897
lamtor5
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr16_+_36748538 0.07 ENSDART00000139069
decr1
2,4-dienoyl CoA reductase 1, mitochondrial
chr10_-_28477023 0.06 ENSDART00000137008
bbx
bobby sox homolog (Drosophila)
chr7_+_39360797 0.06 ENSDART00000173481
acp2
acid phosphatase 2, lysosomal
chr6_+_52212927 0.06 ENSDART00000143458
ywhaba
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a
chr3_+_46762703 0.06 ENSDART00000133283
prkcsh
protein kinase C substrate 80K-H
chr8_-_2616326 0.06 ENSDART00000027214
slc25a25a
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a
chr14_+_24075254 0.05 ENSDART00000181117
AL935195.3

chr14_+_50918769 0.05 ENSDART00000146918
rnf44
ring finger protein 44
chr18_+_26899316 0.04 ENSDART00000050230
tspan3a
tetraspanin 3a
chr14_-_24111292 0.04 ENSDART00000186611
cpeb4a
cytoplasmic polyadenylation element binding protein 4a
chr10_+_31951338 0.04 ENSDART00000019416
lhfpl6
LHFPL tetraspan subfamily member 6
chr18_-_16795262 0.03 ENSDART00000048722
ampd3b
adenosine monophosphate deaminase 3b
chr16_-_21668082 0.03 ENSDART00000088513
gnl1
guanine nucleotide binding protein-like 1
chr15_-_18138607 0.03 ENSDART00000176690
CR385077.1

chr14_-_17599452 0.02 ENSDART00000080042
rab33a
RAB33A, member RAS oncogene family
chr2_+_38161318 0.02 ENSDART00000044264
mmp14b
matrix metallopeptidase 14b (membrane-inserted)
chr7_+_56472585 0.02 ENSDART00000135259
ENSDART00000073596
ist1
increased sodium tolerance 1 homolog (yeast)
chr11_+_26403873 0.02 ENSDART00000109298
fer1l4
fer-1-like family member 4
chr3_-_50139860 0.02 ENSDART00000101563
btr02
bloodthirsty-related gene family, member 2
chr20_-_19365875 0.01 ENSDART00000063703
ENSDART00000187707
ENSDART00000161065
si:dkey-71h2.2
si:dkey-71h2.2
chr21_-_35419486 0.01 ENSDART00000138529
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr1_-_39909985 0.01 ENSDART00000181673
stox2a
storkhead box 2a
chr21_+_3928947 0.01 ENSDART00000149777
setx
senataxin
chr7_+_30875273 0.00 ENSDART00000173693
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b

Network of associatons between targets according to the STRING database.

First level regulatory network of foxb1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 0.6 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.1 0.5 GO:0090299 regulation of neural crest formation(GO:0090299)
0.1 0.6 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 0.7 GO:0071800 podosome assembly(GO:0071800)
0.1 0.4 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1 0.8 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.7 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.1 0.4 GO:0006549 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.1 1.8 GO:0001990 regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.1 1.2 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.1 0.3 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.1 0.6 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.4 GO:0099558 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.1 1.0 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.1 0.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.3 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.3 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.2 GO:0061010 gall bladder development(GO:0061010)
0.0 2.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.7 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.4 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:1901006 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.0 0.8 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.2 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.2 GO:0006309 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.1 GO:1901546 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.0 0.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.7 GO:0051923 sulfation(GO:0051923)
0.0 0.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.2 GO:0002931 response to ischemia(GO:0002931)
0.0 0.3 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.6 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.8 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.0 0.4 GO:0030851 granulocyte differentiation(GO:0030851)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.8 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 2.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 1.1 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.2 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0017177 glucosidase II complex(GO:0017177)
0.0 0.5 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0098978 glutamatergic synapse(GO:0098978)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0046592 polyamine oxidase activity(GO:0046592)
0.1 0.7 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.4 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.6 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.4 GO:0030955 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 3.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.4 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 1.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID CONE PATHWAY Visual signal transduction: Cones
0.1 1.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.7 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels