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PRJEB1986: zebrafish developmental stages transcriptome

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Results for foxd2_foxd5

Z-value: 1.45

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Transcription factors associated with foxd2_foxd5

Gene Symbol Gene ID Gene Info
foxd2
ENSDARG00000058133 forkhead box D2
foxd5
ENSDARG00000042485 forkhead box D5
foxd5
ENSDARG00000109712 forkhead box D5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxd2dr11_v1_chr8_+_19674369_19674369-0.922.5e-08Click!
foxd5dr11_v1_chr8_+_30452945_30452945-0.652.4e-03Click!

Activity profile of foxd2_foxd5 motif

Sorted Z-values of foxd2_foxd5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_3237561 6.28 ENSDART00000164665
si:ch1073-13h15.3
si:ch1073-13h15.3
chr12_-_22524388 5.09 ENSDART00000020942
shbg
sex hormone-binding globulin
chr4_+_7841627 4.49 ENSDART00000037997
ucmaa
upper zone of growth plate and cartilage matrix associated a
chr21_+_40092301 4.38 ENSDART00000145150
serpinf2a
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a
chr15_-_34408777 3.97 ENSDART00000139934
agmo
alkylglycerol monooxygenase
chr4_+_12013043 3.88 ENSDART00000130692
cry1aa
cryptochrome circadian clock 1aa
chr10_+_36650222 3.32 ENSDART00000126963
ucp3
uncoupling protein 3
chr15_-_37829160 3.26 ENSDART00000099425
ctrl
chymotrypsin-like
chr8_+_16004154 2.98 ENSDART00000134787
ENSDART00000172510
ENSDART00000141173
elavl4
ELAV like neuron-specific RNA binding protein 4
chr3_-_21280373 2.89 ENSDART00000003939
syngr1a
synaptogyrin 1a
chr6_+_41186320 2.86 ENSDART00000025241
opn1mw2
opsin 1 (cone pigments), medium-wave-sensitive, 2
chr25_+_24250247 2.77 ENSDART00000064646
tmem86a
transmembrane protein 86A
chr7_-_12909352 2.75 ENSDART00000172901
sh3gl3a
SH3-domain GRB2-like 3a
chr16_-_13388821 2.75 ENSDART00000144062
grin2db
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr25_+_29160102 2.49 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr20_+_34717403 2.45 ENSDART00000034252
pnocb
prepronociceptin b
chr9_+_34127005 2.41 ENSDART00000167384
ENSDART00000078065
f5
coagulation factor V
chr25_+_4760489 2.41 ENSDART00000167399
FP245455.1

chr5_+_26795465 2.39 ENSDART00000053001
tcn2
transcobalamin II
chr23_-_44219902 2.33 ENSDART00000185874
zgc:158659
zgc:158659
chr6_-_24053404 2.25 ENSDART00000168511
si:dkey-44g17.6
si:dkey-44g17.6
chr14_-_4121052 2.25 ENSDART00000167074
irf2
interferon regulatory factor 2
chr25_+_19149241 2.23 ENSDART00000184982
ENSDART00000067324
mfge8b
milk fat globule-EGF factor 8 protein b
chr16_-_44349845 2.18 ENSDART00000170932
rims2a
regulating synaptic membrane exocytosis 2a
chr20_+_36233873 2.08 ENSDART00000131867
cnih3
cornichon family AMPA receptor auxiliary protein 3
chr2_-_9748039 2.04 ENSDART00000134870
si:ch1073-170o4.1
si:ch1073-170o4.1
chr1_-_37087966 2.03 ENSDART00000172111
ENSDART00000160056
nr3c2
nuclear receptor subfamily 3, group C, member 2
chr18_-_6803424 2.00 ENSDART00000142647
si:dkey-266m15.5
si:dkey-266m15.5
chr1_-_30473422 1.96 ENSDART00000164202
igf2bp2b
insulin-like growth factor 2 mRNA binding protein 2b
chr24_-_35707552 1.95 ENSDART00000165199
mapre2
microtubule-associated protein, RP/EB family, member 2
chr14_-_4120636 1.91 ENSDART00000059230
irf2
interferon regulatory factor 2
chr10_+_26972755 1.91 ENSDART00000042162
tm7sf2
transmembrane 7 superfamily member 2
chr12_+_40905427 1.88 ENSDART00000170526
ENSDART00000185771
ENSDART00000193945
CDH18
cadherin 18
chr11_+_6295370 1.80 ENSDART00000139882
ranbp3a
RAN binding protein 3a
chr15_+_45563656 1.77 ENSDART00000157501
cldn15lb
claudin 15-like b
chr14_+_46410766 1.77 ENSDART00000032342
anxa5a
annexin A5a
chr6_+_40671336 1.75 ENSDART00000111639
ENSDART00000186617
rereb
arginine-glutamic acid dipeptide (RE) repeats b
chr3_-_28828242 1.74 ENSDART00000151445
si:ch211-76l23.4
si:ch211-76l23.4
chr13_-_30662403 1.69 ENSDART00000012457
si:dkey-275b16.2
si:dkey-275b16.2
chr18_+_14277003 1.69 ENSDART00000006628
zgc:173742
zgc:173742
chr11_-_37880492 1.65 ENSDART00000102868
etnk2
ethanolamine kinase 2
chr10_+_33744098 1.65 ENSDART00000147775
rxfp2a
relaxin/insulin-like family peptide receptor 2a
chr6_-_55864687 1.65 ENSDART00000160991
cyp24a1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr14_-_33894915 1.64 ENSDART00000143290
urp1
urotensin-related peptide 1
chr7_+_21841037 1.47 ENSDART00000077503
tm4sf5
transmembrane 4 L six family member 5
chr3_+_34683096 1.47 ENSDART00000084432
dusp3b
dual specificity phosphatase 3b
chr20_+_43083745 1.46 ENSDART00000139014
ENSDART00000153438
moxd1l
monooxygenase, DBH-like 1, like
chr13_+_32446169 1.43 ENSDART00000143325
nt5c1ba
5'-nucleotidase, cytosolic IB a
chr5_-_45634675 1.40 ENSDART00000168534
NPFFR2
neuropeptide FF receptor 2a
chr8_+_23142946 1.39 ENSDART00000152933
si:ch211-196c10.13
si:ch211-196c10.13
chr20_-_9963713 1.34 ENSDART00000104234
gjd2b
gap junction protein delta 2b
chr16_-_29334672 1.33 ENSDART00000162835
bcan
brevican
chr17_+_30448452 1.30 ENSDART00000153939
lpin1
lipin 1
chr14_-_4556896 1.30 ENSDART00000044678
ENSDART00000192863
GABRA2
gamma-aminobutyric acid type A receptor alpha2 subunit
chr18_-_16181952 1.25 ENSDART00000157824
slc6a15
solute carrier family 6 (neutral amino acid transporter), member 15
chr18_-_17077419 1.21 ENSDART00000148714
il17c
interleukin 17c
chr15_+_45563491 1.21 ENSDART00000191169
cldn15lb
claudin 15-like b
chr17_-_29311835 1.19 ENSDART00000104224
tecpr2
tectonin beta-propeller repeat containing 2
chr10_+_26973063 1.18 ENSDART00000143162
ENSDART00000186210
tm7sf2
transmembrane 7 superfamily member 2
chr14_+_11457500 1.18 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr5_+_32206378 1.18 ENSDART00000126873
ENSDART00000051361
myhz2
myosin, heavy polypeptide 2, fast muscle specific
chr2_-_4787566 1.16 ENSDART00000160663
ENSDART00000157808
tnk2b
tyrosine kinase, non-receptor, 2b
chr14_+_11458044 1.14 ENSDART00000186425
si:ch211-153b23.5
si:ch211-153b23.5
chr6_-_40697585 1.14 ENSDART00000113196
si:ch211-157b11.14
si:ch211-157b11.14
chr8_+_16004551 1.12 ENSDART00000165141
elavl4
ELAV like neuron-specific RNA binding protein 4
chr19_+_9186175 1.08 ENSDART00000039325
hcn3
hyperpolarization activated cyclic nucleotide-gated potassium channel 3
chr12_-_36260532 1.07 ENSDART00000022533
kcnj2a
potassium inwardly-rectifying channel, subfamily J, member 2a
chr19_+_32807236 1.05 ENSDART00000008698
stk3
serine/threonine kinase 3 (STE20 homolog, yeast)
chr7_-_35515931 1.04 ENSDART00000193324
irx6a
iroquois homeobox 6a
chr20_-_3166168 1.01 ENSDART00000134137
si:ch73-212j7.3
si:ch73-212j7.3
chr14_-_41556720 1.00 ENSDART00000149244
itga6l
integrin, alpha 6, like
chr22_+_1779401 0.98 ENSDART00000170126
znf1154
zinc finger protein 1154
chr5_+_13385837 0.95 ENSDART00000191190
ccl19a.1
chemokine (C-C motif) ligand 19a, tandem duplicate 1
chr6_+_2097690 0.94 ENSDART00000193770
tgm2b
transglutaminase 2b
chr2_-_37960688 0.93 ENSDART00000055565
cbln14
cerebellin 14
chr17_-_29312506 0.93 ENSDART00000133668
tecpr2
tectonin beta-propeller repeat containing 2
chr12_+_2648043 0.88 ENSDART00000082220
gdf2
growth differentiation factor 2
chr4_+_74551606 0.88 ENSDART00000174339
kcna1b
potassium voltage-gated channel, shaker-related subfamily, member 1b
chr21_-_18993110 0.88 ENSDART00000144086
si:ch211-222n4.6
si:ch211-222n4.6
chr24_+_5840258 0.88 ENSDART00000087034
trpc1
transient receptor potential cation channel, subfamily C, member 1
chr1_-_10473630 0.87 ENSDART00000040116
tnrc5
trinucleotide repeat containing 5
chr16_-_16619854 0.86 ENSDART00000150512
ENSDART00000191306
ENSDART00000181773
ENSDART00000183231
cyp21a2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr7_+_65387374 0.86 ENSDART00000188680
CLEC3A
C-type lectin domain family 3 member A
chr13_+_32740509 0.85 ENSDART00000076423
ENSDART00000160138
sobpa
sine oculis binding protein homolog (Drosophila) a
chr11_-_25730416 0.84 ENSDART00000191612
brpf3a
bromodomain and PHD finger containing, 3a
chr9_+_22677503 0.82 ENSDART00000131429
ENSDART00000080005
ENSDART00000101756
ENSDART00000138148
itgb5
integrin, beta 5
chr24_+_8904741 0.80 ENSDART00000140924
gnal
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr14_+_21107032 0.80 ENSDART00000138319
ENSDART00000139103
ENSDART00000184735
aldob
aldolase b, fructose-bisphosphate
chr6_+_9870192 0.80 ENSDART00000150894
MPP4 (1 of many)
si:ch211-222n4.6
chr13_+_16521898 0.80 ENSDART00000122557
kcnma1a
potassium large conductance calcium-activated channel, subfamily M, alpha member 1a
chr9_+_52398531 0.80 ENSDART00000126215
dap1b
death associated protein 1b
chr18_+_13837746 0.79 ENSDART00000169552
cdh13
cadherin 13, H-cadherin (heart)
chr19_-_31522625 0.78 ENSDART00000158438
ENSDART00000035049
necab1
N-terminal EF-hand calcium binding protein 1
chr4_+_12013642 0.78 ENSDART00000067281
cry1aa
cryptochrome circadian clock 1aa
chr19_+_32201991 0.73 ENSDART00000022667
fam8a1a
family with sequence similarity 8, member A1a
chr16_+_11724230 0.72 ENSDART00000060266
ceacam1
carcinoembryonic antigen-related cell adhesion molecule 1
chr23_-_42810664 0.70 ENSDART00000102328
pfkfb2a
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr8_+_26410197 0.69 ENSDART00000145836
ENSDART00000053447
ifrd2
interferon-related developmental regulator 2
chr20_+_27647436 0.69 ENSDART00000180557
ENSDART00000185628
mthfd1a
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1a, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
chr5_-_67750907 0.68 ENSDART00000172097
b4galt4
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr11_+_41858807 0.67 ENSDART00000161605
iffo2b
intermediate filament family orphan 2b
chr20_+_36234335 0.67 ENSDART00000193484
ENSDART00000181664
cnih3
cornichon family AMPA receptor auxiliary protein 3
chr10_-_25543227 0.66 ENSDART00000007778
grik1a
glutamate receptor, ionotropic, kainate 1a
chr23_-_35790235 0.66 ENSDART00000142369
ENSDART00000141141
ENSDART00000011004
mfsd5
major facilitator superfamily domain containing 5
chr20_-_30369598 0.66 ENSDART00000144549
allc
allantoicase
chr18_+_19419120 0.65 ENSDART00000025107
map2k1
mitogen-activated protein kinase kinase 1
chr15_+_24691088 0.65 ENSDART00000110618
LRRC75A
si:dkey-151p21.7
chr21_+_27416284 0.64 ENSDART00000077593
ENSDART00000108763
cfb
complement factor B
chr17_-_19963718 0.63 ENSDART00000154251
chrm3a
cholinergic receptor, muscarinic 3a
chr9_-_16109001 0.63 ENSDART00000053473
upp2
uridine phosphorylase 2
chr22_-_11493236 0.61 ENSDART00000002691
tspan7b
tetraspanin 7b
chr4_+_57093908 0.61 ENSDART00000170198
si:ch211-238e22.5
si:ch211-238e22.5
chr8_+_9149436 0.60 ENSDART00000064090
pnck
pregnancy up-regulated nonubiquitous CaM kinase
chr12_-_20120702 0.60 ENSDART00000153387
ENSDART00000158412
ENSDART00000112768
ubald1a
UBA-like domain containing 1a
chr15_+_24212847 0.59 ENSDART00000155502
sez6b
seizure related 6 homolog b
chr8_+_7975745 0.59 ENSDART00000137920
si:ch211-169p10.1
si:ch211-169p10.1
chr24_-_22756508 0.59 ENSDART00000035409
ENSDART00000146247
zc2hc1a
zinc finger, C2HC-type containing 1A
chr10_-_35236949 0.59 ENSDART00000145804
ypel2a
yippee-like 2a
chr5_+_4575800 0.58 ENSDART00000180952
cst14b.2
cystatin 14b, tandem duplicate 2
chr20_-_25436389 0.58 ENSDART00000153266
itsn2a
intersectin 2a
chr9_+_45789887 0.57 ENSDART00000135202
si:dkey-34f9.3
si:dkey-34f9.3
chr22_-_9728208 0.56 ENSDART00000185962
si:dkey-286j17.4
si:dkey-286j17.4
chr7_+_53156810 0.56 ENSDART00000189816
cdh29
cadherin 29
chr3_-_45848043 0.54 ENSDART00000055132
igfals
insulin-like growth factor binding protein, acid labile subunit
chr7_+_35245607 0.54 ENSDART00000193422
ENSDART00000173888
amfrb
autocrine motility factor receptor b
chr19_+_7043634 0.52 ENSDART00000133954
mhc1uka
major histocompatibility complex class I UKA
chr1_+_44582369 0.52 ENSDART00000003022
ENSDART00000137980
med19b
mediator complex subunit 19b
chr3_-_34724879 0.52 ENSDART00000177021
thraa
thyroid hormone receptor alpha a
chr3_+_25216790 0.51 ENSDART00000156544
c1qtnf6a
C1q and TNF related 6a
chr5_-_69707787 0.51 ENSDART00000108820
ENSDART00000149692
dguok
deoxyguanosine kinase
chr3_-_45848257 0.50 ENSDART00000147198
igfals
insulin-like growth factor binding protein, acid labile subunit
chr14_-_33613794 0.50 ENSDART00000010022
xpnpep2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr6_-_40098641 0.50 ENSDART00000017402
ip6k2b
inositol hexakisphosphate kinase 2b
chr11_-_13152215 0.49 ENSDART00000160989
ENSDART00000158239
elovl1b
ELOVL fatty acid elongase 1b
chr17_+_11507131 0.49 ENSDART00000013170
kif26ba
kinesin family member 26Ba
chr8_-_47329755 0.48 ENSDART00000060853
pex10
peroxisomal biogenesis factor 10
chr12_+_28986308 0.48 ENSDART00000153178
si:rp71-1c10.8
si:rp71-1c10.8
chr15_+_23911655 0.46 ENSDART00000156304
si:ch1073-145m9.1
si:ch1073-145m9.1
chr15_-_16121496 0.44 ENSDART00000128624
sgk494a
uncharacterized serine/threonine-protein kinase SgK494a
chr12_+_29173523 0.43 ENSDART00000153212
adgra1a
adhesion G protein-coupled receptor A1a
chr18_-_5111449 0.42 ENSDART00000046902
pdcd10a
programmed cell death 10a
chr2_-_985417 0.42 ENSDART00000140540
si:ch211-241e1.3
si:ch211-241e1.3
chr5_+_22970617 0.42 ENSDART00000192859
hmgn7
high mobility group nucleosomal binding domain 7
chr20_-_49889111 0.42 ENSDART00000058858
kif13bb
kinesin family member 13Bb
chr12_-_5455936 0.41 ENSDART00000109305
tbc1d12b
TBC1 domain family, member 12b
chr17_+_12942634 0.40 ENSDART00000016597
nfkbiab
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b
chr17_-_24564674 0.40 ENSDART00000105435
ENSDART00000135086
abch1
ATP-binding cassette, sub-family H, member 1
chr19_+_32856907 0.37 ENSDART00000148232
rpl30
ribosomal protein L30
chr24_+_7631797 0.36 ENSDART00000187464
cavin1b
caveolae associated protein 1b
chr2_-_48171112 0.36 ENSDART00000156258
pfkpb
phosphofructokinase, platelet b
chr16_+_23975930 0.35 ENSDART00000147858
ENSDART00000144347
ENSDART00000115270
apoc4
apolipoprotein C-IV
chr4_-_7212875 0.35 ENSDART00000161297
lrrn3b
leucine rich repeat neuronal 3b
chr1_+_532766 0.35 ENSDART00000179731
ENSDART00000060944
mrpl39
mitochondrial ribosomal protein L39
chr18_-_17077596 0.35 ENSDART00000111821
il17c
interleukin 17c
chr17_+_12942021 0.35 ENSDART00000192514
nfkbiab
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b
chr2_+_23007675 0.34 ENSDART00000163649
mknk2a
MAP kinase interacting serine/threonine kinase 2a
chr10_+_39248911 0.34 ENSDART00000170079
ENSDART00000167974
foxred1
FAD-dependent oxidoreductase domain containing 1
chr6_+_40437987 0.34 ENSDART00000136487
ghrl
ghrelin/obestatin prepropeptide
chr3_+_36424055 0.33 ENSDART00000170318
si:ch1073-443f11.2
si:ch1073-443f11.2
chr20_-_51267185 0.33 ENSDART00000158350
ENSDART00000023064
slc35b2
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
chr22_+_1586060 0.32 ENSDART00000160793
si:ch211-255f4.11
si:ch211-255f4.11
chr18_-_37007294 0.31 ENSDART00000088309
map3k10
mitogen-activated protein kinase kinase kinase 10
chr16_-_52966811 0.31 ENSDART00000153758
ENSDART00000009256
brd9
bromodomain containing 9
chr15_+_32867420 0.30 ENSDART00000159442
dclk1b
doublecortin-like kinase 1b
chr2_-_127945 0.30 ENSDART00000056453
igfbp1b
insulin-like growth factor binding protein 1b
chr7_+_13039426 0.29 ENSDART00000171777
syt7b
synaptotagmin VIIb
chr1_-_656693 0.28 ENSDART00000170483
ENSDART00000166786
appa
amyloid beta (A4) precursor protein a
chr15_-_5157572 0.27 ENSDART00000174192
or128-10
odorant receptor, family E, subfamily 128, member 10
chr22_-_15562933 0.27 ENSDART00000141528
ankmy1
ankyrin repeat and MYND domain containing 1
chr18_-_37007061 0.27 ENSDART00000136432
map3k10
mitogen-activated protein kinase kinase kinase 10
chr16_+_46492994 0.26 ENSDART00000134734
rpz5
rapunzel 5
chr21_-_39327223 0.26 ENSDART00000115097
aifm5
apoptosis-inducing factor, mitochondrion-associated, 5
chr11_-_40742424 0.25 ENSDART00000173399
ENSDART00000021369
tas1r3
taste receptor, type 1, member 3
chr8_+_19624589 0.25 ENSDART00000185698
slc35a3a
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a
chr19_-_42238440 0.25 ENSDART00000132591
si:ch211-191i18.4
si:ch211-191i18.4
chr11_-_13152524 0.25 ENSDART00000181440
ENSDART00000191997
elovl1b
ELOVL fatty acid elongase 1b
chr10_+_34315719 0.24 ENSDART00000135303
stard13a
StAR-related lipid transfer (START) domain containing 13a
chr6_+_24661736 0.24 ENSDART00000169283
znf644b
zinc finger protein 644b
chr17_+_8292892 0.23 ENSDART00000125728
si:ch211-236p5.3
si:ch211-236p5.3
chr15_+_17623115 0.23 ENSDART00000062378
adamts15b
ADAM metallopeptidase with thrombospondin type 1 motif, 15b
chr5_-_50600512 0.23 ENSDART00000190318
mctp1a
multiple C2 domains, transmembrane 1a
chr22_-_38819603 0.22 ENSDART00000104437
si:ch211-262h13.5
si:ch211-262h13.5
chr7_+_32722227 0.22 ENSDART00000126565
si:ch211-150g13.3
si:ch211-150g13.3
chr5_-_62988463 0.22 ENSDART00000047143
specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr19_+_9277327 0.21 ENSDART00000104623
ENSDART00000151164
si:rp71-15k1.1
si:rp71-15k1.1
chr14_+_36628131 0.21 ENSDART00000188625
ENSDART00000125345
TENM3
si:dkey-237h12.3
chr4_-_21851473 0.21 ENSDART00000019748
lin7a
lin-7 homolog A (C. elegans)
chr5_+_33070608 0.21 ENSDART00000135063
npffr2b
neuropeptide FF receptor 2b
chr10_+_26597990 0.20 ENSDART00000079187
fhl1b
four and a half LIM domains 1b
chr4_-_5913338 0.20 ENSDART00000183590
arl1
ADP-ribosylation factor-like 1
chr25_-_19486399 0.19 ENSDART00000155076
ENSDART00000156016
zgc:193812
zgc:193812
chr17_+_31914877 0.19 ENSDART00000177801
FAM196A (1 of many)
family with sequence similarity 196 member A
chr8_+_35212233 0.19 ENSDART00000111021
si:dkeyp-14d3.1
si:dkeyp-14d3.1
chr20_+_47196506 0.18 ENSDART00000153040
znf975
zinc finger protein 975
chr19_+_11984725 0.17 ENSDART00000185960
spag1a
sperm associated antigen 1a
chr15_+_25489406 0.17 ENSDART00000162482
zgc:152863
zgc:152863
chr22_+_11867639 0.17 ENSDART00000144677
mras
muscle RAS oncogene homolog
chr24_+_13642126 0.17 ENSDART00000126769
trpa1b
transient receptor potential cation channel, subfamily A, member 1b
chr2_-_51507540 0.16 ENSDART00000166605
ENSDART00000161093
pigrl2.3
polymeric immunoglobulin receptor-like 2.3
chr8_+_37749263 0.16 ENSDART00000108556
ENSDART00000147942
npm2a
nucleophosmin/nucleoplasmin, 2a

Network of associatons between targets according to the STRING database.

First level regulatory network of foxd2_foxd5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0006824 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.8 4.0 GO:0046485 ether lipid metabolic process(GO:0046485)
0.5 1.6 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.5 2.0 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
0.5 1.5 GO:0006589 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.4 3.3 GO:1990845 adaptive thermogenesis(GO:1990845)
0.3 1.2 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.3 4.5 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.2 0.7 GO:0043605 allantoin catabolic process(GO:0000256) cellular amide catabolic process(GO:0043605)
0.2 2.0 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.2 0.6 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.2 1.8 GO:0050819 negative regulation of coagulation(GO:0050819)
0.2 1.8 GO:0006611 protein export from nucleus(GO:0006611)
0.2 0.8 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 2.7 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 0.4 GO:1903358 regulation of Golgi organization(GO:1903358)
0.1 1.6 GO:0045762 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.1 0.9 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 2.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 2.3 GO:0014823 response to activity(GO:0014823)
0.1 0.8 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 3.0 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 1.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 3.1 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.1 1.7 GO:0006265 DNA topological change(GO:0006265)
0.1 2.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.8 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.1 2.7 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.4 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 0.6 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.1 0.8 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 3.0 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.8 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 3.6 GO:0006096 glycolytic process(GO:0006096)
0.1 0.2 GO:0007635 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.1 0.5 GO:0032095 regulation of response to food(GO:0032095)
0.1 0.5 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.1 0.7 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.7 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.4 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0 3.8 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.9 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.4 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 1.3 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.1 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.7 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 1.0 GO:0035329 hippo signaling(GO:0035329)
0.0 0.9 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.8 GO:0034198 negative regulation of autophagy(GO:0010507) cellular response to amino acid starvation(GO:0034198)
0.0 0.1 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.0 0.1 GO:0046443 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.0 0.5 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.6 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.2 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 1.7 GO:0007599 hemostasis(GO:0007599)
0.0 0.5 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.1 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.0 0.9 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.7 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 2.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.6 GO:0008217 regulation of blood pressure(GO:0008217)
0.0 0.3 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.1 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214) cardiac left ventricle formation(GO:0003218)
0.0 0.3 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 0.9 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.3 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0042359 response to vitamin D(GO:0033280) vitamin D metabolic process(GO:0042359)
0.0 0.3 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.4 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 1.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.6 GO:0007338 single fertilization(GO:0007338)
0.0 2.0 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.6 GO:0072376 complement activation(GO:0006956) protein activation cascade(GO:0072376)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 2.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.4 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.1 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 2.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 1.3 GO:0005922 connexon complex(GO:0005922)
0.1 2.9 GO:0031594 neuromuscular junction(GO:0031594)
0.1 4.1 GO:0043204 perikaryon(GO:0043204)
0.1 0.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 2.2 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.1 2.4 GO:0043679 axon terminus(GO:0043679)
0.1 1.8 GO:0035371 microtubule plus-end(GO:0035371)
0.1 3.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 2.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 1.5 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.8 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 2.5 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 1.3 GO:0008305 integrin complex(GO:0008305)
0.0 3.0 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 6.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.6 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.4 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 1.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.6 GO:0042734 presynaptic membrane(GO:0042734)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.5 1.5 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.4 4.0 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.4 2.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.4 1.6 GO:0070643 vitamin D 25-hydroxylase activity(GO:0070643)
0.3 6.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.3 2.8 GO:0016803 ether hydrolase activity(GO:0016803)
0.3 1.7 GO:0046592 polyamine oxidase activity(GO:0046592)
0.3 2.4 GO:0031419 cobalamin binding(GO:0031419)
0.3 1.3 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.2 1.2 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.2 2.3 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.2 2.7 GO:0031628 opioid receptor binding(GO:0031628)
0.2 2.0 GO:1990239 steroid hormone binding(GO:1990239)
0.2 0.8 GO:0070513 death domain binding(GO:0070513)
0.1 2.7 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 1.7 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 3.1 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 2.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.7 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 5.1 GO:0042562 hormone binding(GO:0042562)
0.1 0.4 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.7 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.5 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 3.0 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.8 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 0.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.1 1.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.9 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 2.4 GO:0044325 ion channel binding(GO:0044325)
0.0 2.4 GO:0005507 copper ion binding(GO:0005507)
0.0 0.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.7 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0008443 phosphofructokinase activity(GO:0008443)
0.0 3.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.0 1.1 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 1.1 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.3 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.7 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.7 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 0.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 2.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.5 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 3.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.5 GO:0005125 cytokine activity(GO:0005125)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 2.1 GO:0005179 hormone activity(GO:0005179)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 1.0 GO:0008395 steroid hydroxylase activity(GO:0008395)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.7 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 0.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.9 REACTOME OPSINS Genes involved in Opsins
0.3 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 4.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.2 3.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 2.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 0.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 3.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 0.7 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 1.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 3.3 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1 1.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.1 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 1.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway