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PRJEB1986: zebrafish developmental stages transcriptome

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Results for foxj1a+foxj1b

Z-value: 1.57

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Transcription factors associated with foxj1a+foxj1b

Gene Symbol Gene ID Gene Info
foxj1b
ENSDARG00000088290 forkhead box J1b
foxj1a
ENSDARG00000101919 forkhead box J1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxj1adr11_v1_chr3_+_60721342_607213420.787.1e-05Click!
foxj1bdr11_v1_chr12_+_20149707_201497070.581.0e-02Click!

Activity profile of foxj1a+foxj1b motif

Sorted Z-values of foxj1a+foxj1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_20167206 4.83 ENSDART00000104874
ENSDART00000191995
p4ha1b
prolyl 4-hydroxylase, alpha polypeptide I b
chr14_-_41478265 4.62 ENSDART00000149886
ENSDART00000016002
tspan7
tetraspanin 7
chr10_-_35257458 4.18 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
prr11
proline rich 11
chr8_-_16697912 3.57 ENSDART00000076542
rpe65b
retinal pigment epithelium-specific protein 65b
chr14_-_35462148 3.54 ENSDART00000045809
srpx2
sushi-repeat containing protein, X-linked 2
chr15_+_26933196 3.54 ENSDART00000023842
ppm1da
protein phosphatase, Mg2+/Mn2+ dependent, 1Da
chr16_+_40576679 3.49 ENSDART00000169412
ENSDART00000193464
ccne2
cyclin E2
chr1_+_9153141 3.40 ENSDART00000081343
plk1
polo-like kinase 1 (Drosophila)
chr15_+_34069746 3.31 ENSDART00000163513
arl4aa
ADP-ribosylation factor-like 4aa
chr2_+_19195841 3.24 ENSDART00000163137
ENSDART00000161095
elovl1a
ELOVL fatty acid elongase 1a
chr7_-_28611145 3.14 ENSDART00000054366
scube2
signal peptide, CUB domain, EGF-like 2
chr17_-_28100741 3.12 ENSDART00000180532
kdm1a
lysine (K)-specific demethylase 1a
chr14_+_26439227 3.12 ENSDART00000054183
gpr137
G protein-coupled receptor 137
chr17_-_28100501 2.86 ENSDART00000149543
kdm1a
lysine (K)-specific demethylase 1a
chr4_+_27100531 2.84 ENSDART00000115200
alg12
ALG12, alpha-1,6-mannosyltransferase
chr23_+_28077953 2.82 ENSDART00000186122
ENSDART00000111570
slc26a10
solute carrier family 26, member 10
chr10_-_3416258 2.72 ENSDART00000005168
ddx55
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
chr2_-_42958113 2.71 ENSDART00000139945
oc90
otoconin 90
chr2_+_20866898 2.70 ENSDART00000150086
odr4
odr-4 GPCR localization factor homolog
chr16_-_31435020 2.62 ENSDART00000138508
zgc:194210
zgc:194210
chr17_-_35881841 2.62 ENSDART00000110040
sox11a
SRY (sex determining region Y)-box 11a
chr7_-_33023404 2.59 ENSDART00000052383
cd81a
CD81 molecule a
chr9_-_1990323 2.55 ENSDART00000082332
hoxd13a
homeobox D13a
chr5_-_20446082 2.55 ENSDART00000051607
ISCU (1 of many)
si:ch211-191d15.2
chr10_+_10728870 2.51 ENSDART00000109282
swi5
SWI5 homologous recombination repair protein
chr13_-_21650404 2.47 ENSDART00000078352
tspan14
tetraspanin 14
chr11_+_16153207 2.45 ENSDART00000192356
tada3l
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr24_+_39211288 2.45 ENSDART00000061540
im:7160594
im:7160594
chr15_-_17960228 2.40 ENSDART00000155898
phldb1b
pleckstrin homology-like domain, family B, member 1b
chr8_-_1267247 2.39 ENSDART00000150064
cdc14b
cell division cycle 14B
chr9_+_2041535 2.37 ENSDART00000093187
lnpa
limb and neural patterns a
chr6_-_9695294 2.36 ENSDART00000162728
nop58
NOP58 ribonucleoprotein homolog (yeast)
chr7_-_60831082 2.36 ENSDART00000073654
ENSDART00000136999
pcxb
pyruvate carboxylase b
chr7_-_26270014 2.35 ENSDART00000079347
serpine1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr5_+_60847823 2.34 ENSDART00000074426
lig3
ligase III, DNA, ATP-dependent
chr13_+_18533005 2.34 ENSDART00000136024
ftr14l
finTRIM family, member 14-like
chr20_+_15552657 2.27 ENSDART00000063912
jun
Jun proto-oncogene, AP-1 transcription factor subunit
chr4_-_6373735 2.26 ENSDART00000140100
MDFIC
si:ch73-156e19.1
chr15_-_44052927 2.24 ENSDART00000166209
wu:fb44b02
wu:fb44b02
chr13_+_5978809 2.23 ENSDART00000102563
ENSDART00000121598
phf10
PHD finger protein 10
chr9_+_41459759 2.23 ENSDART00000132501
ENSDART00000100265
nemp2
nuclear envelope integral membrane protein 2
chr13_-_31687925 2.23 ENSDART00000085989
trmt5
TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
chr18_+_6857071 2.22 ENSDART00000018735
ENSDART00000181969
dnaja2l
DnaJ (Hsp40) homolog, subfamily A, member 2, like
chr10_+_22775253 2.21 ENSDART00000190141
tmem88a
transmembrane protein 88 a
chr19_+_20177887 2.21 ENSDART00000008595
tra2a
transformer 2 alpha homolog
chr25_-_31423493 2.20 ENSDART00000027661
myod1
myogenic differentiation 1
chr12_+_18899396 2.16 ENSDART00000105858
xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr6_-_14038804 2.14 ENSDART00000184606
ENSDART00000184609
etv5b
ets variant 5b
chr7_+_38808027 2.13 ENSDART00000052323
harbi1
harbinger transposase derived 1
chr24_+_19542323 2.12 ENSDART00000140379
ENSDART00000142830
sulf1
sulfatase 1
chr13_-_31647323 2.12 ENSDART00000135381
six4a
SIX homeobox 4a
chr2_+_38271392 2.10 ENSDART00000042100
homeza
homeobox and leucine zipper encoding a
chr7_-_50367642 2.08 ENSDART00000134941
prc1b
protein regulator of cytokinesis 1b
chr16_+_26732086 2.08 ENSDART00000138496
rad54b
RAD54 homolog B (S. cerevisiae)
chr24_-_25461267 2.06 ENSDART00000105820
mbtps2
membrane-bound transcription factor peptidase, site 2
chr18_+_20226843 2.06 ENSDART00000100632
tle3a
transducin-like enhancer of split 3a
chr1_+_53945934 2.05 ENSDART00000052838
acta1a
actin, alpha 1a, skeletal muscle
chr10_-_23099809 2.04 ENSDART00000148333
ENSDART00000079703
ENSDART00000162444
nle1
notchless homolog 1 (Drosophila)
chr12_+_3912544 2.03 ENSDART00000013465
tbx6
T-box 6
chr17_-_27273296 2.03 ENSDART00000077087
id3
inhibitor of DNA binding 3
chr19_+_25971000 2.00 ENSDART00000089836
jarid2b
jumonji, AT rich interactive domain 2b
chr5_+_12528693 1.98 ENSDART00000051670
rfc5
replication factor C (activator 1) 5
chr6_-_40922971 1.97 ENSDART00000155363
sfi1
SFI1 centrin binding protein
chr13_-_25842074 1.95 ENSDART00000015154
papolg
poly(A) polymerase gamma
chr8_-_39859688 1.94 ENSDART00000019907
unc119.1
unc-119 homolog 1
chr2_+_16696052 1.94 ENSDART00000022356
ENSDART00000164329
ppp1r7
protein phosphatase 1, regulatory (inhibitor) subunit 7
chr22_+_10232527 1.94 ENSDART00000139297
si:dkeyp-87e7.4
si:dkeyp-87e7.4
chr6_-_10728057 1.92 ENSDART00000002247
sp3b
Sp3b transcription factor
chr11_-_16152400 1.89 ENSDART00000123665
arpc4l
actin related protein 2/3 complex, subunit 4, like
chr22_+_37631234 1.89 ENSDART00000007346
psmd1
proteasome 26S subunit, non-ATPase 1
chr2_-_30200206 1.89 ENSDART00000130142
ube2w
ubiquitin-conjugating enzyme E2W (putative)
chr23_-_17450746 1.88 ENSDART00000145399
ENSDART00000136457
ENSDART00000133125
ENSDART00000145719
ENSDART00000147524
ENSDART00000005366
ENSDART00000104680
tpd52l2b
tumor protein D52-like 2b
chr23_+_7692042 1.87 ENSDART00000018512
pofut1
protein O-fucosyltransferase 1
chr20_-_36800002 1.87 ENSDART00000015190
ptrhd1
peptidyl-tRNA hydrolase domain containing 1
chr11_+_16152316 1.83 ENSDART00000081054
tada3l
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr19_-_22843480 1.83 ENSDART00000052503
nudcd1
NudC domain containing 1
chr18_-_24988645 1.79 ENSDART00000136434
ENSDART00000085735
chd2
chromodomain helicase DNA binding protein 2
chr25_+_19734038 1.79 ENSDART00000067354
zgc:101783
zgc:101783
chr16_-_41131578 1.79 ENSDART00000102649
ENSDART00000145956
ptpn23a
protein tyrosine phosphatase, non-receptor type 23, a
chr7_-_26844064 1.78 ENSDART00000162241
si:ch211-107p11.3
si:ch211-107p11.3
chr16_-_7228276 1.77 ENSDART00000149030
nt5c3a
5'-nucleotidase, cytosolic IIIA
chr17_+_24718272 1.77 ENSDART00000007271
mtfr1l
mitochondrial fission regulator 1-like
chr23_-_43424510 1.76 ENSDART00000055564
rprd1b
regulation of nuclear pre-mRNA domain containing 1B
chr16_-_24605969 1.76 ENSDART00000163305
ENSDART00000167121
fxyd6l
FXYD domain containing ion transport regulator 6 like
chr4_-_20135919 1.75 ENSDART00000172230
cep83
centrosomal protein 83
chr16_+_33121260 1.73 ENSDART00000058472
akirin1
akirin 1
chr15_-_25527580 1.71 ENSDART00000167005
ENSDART00000157498
hif1al
hypoxia-inducible factor 1, alpha subunit, like
chr13_+_29926094 1.71 ENSDART00000057528
cuedc2
CUE domain containing 2
chr1_+_11107688 1.70 ENSDART00000109858
knstrn
kinetochore-localized astrin/SPAG5 binding protein
chr13_+_29773153 1.68 ENSDART00000144443
ENSDART00000133796
ENSDART00000141310
ENSDART00000139782
pax2a
paired box 2a
chr19_+_4968947 1.68 ENSDART00000003634
ENSDART00000134808
stard3
StAR-related lipid transfer (START) domain containing 3
chr10_+_35257651 1.65 ENSDART00000028940
styxl1
serine/threonine/tyrosine interacting-like 1
chr23_+_31596441 1.65 ENSDART00000053534
tbpl1
TBP-like 1
chr7_-_28549361 1.64 ENSDART00000173918
ENSDART00000054368
ENSDART00000113313
st5
suppression of tumorigenicity 5
chr1_+_47178529 1.64 ENSDART00000158432
ENSDART00000074450
ENSDART00000137448
morc3b
MORC family CW-type zinc finger 3b
chr16_-_13595027 1.62 ENSDART00000060004
ntd5
ntl-dependent gene 5
chr16_+_33121106 1.62 ENSDART00000110195
akirin1
akirin 1
chr1_-_51720633 1.62 ENSDART00000045894
rnaseh2a
ribonuclease H2, subunit A
chr7_+_48805534 1.61 ENSDART00000145375
ENSDART00000148744
cpt1aa
carnitine palmitoyltransferase 1Aa (liver)
chr16_+_9580699 1.60 ENSDART00000165565
taf2
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr15_+_23784842 1.60 ENSDART00000192889
ENSDART00000138375
ift20
intraflagellar transport 20 homolog (Chlamydomonas)
chr3_-_36419641 1.58 ENSDART00000173545
cog1
component of oligomeric golgi complex 1
chr2_+_1988036 1.58 ENSDART00000155956
ssx2ipa
synovial sarcoma, X breakpoint 2 interacting protein a
chr6_-_10728921 1.57 ENSDART00000151484
sp3b
Sp3b transcription factor
chr13_+_29925397 1.57 ENSDART00000123482
cuedc2
CUE domain containing 2
chr7_+_48805725 1.56 ENSDART00000166543
cpt1aa
carnitine palmitoyltransferase 1Aa (liver)
chr6_-_37745508 1.55 ENSDART00000078316
nipa2
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr19_+_5315987 1.55 ENSDART00000145749
si:dkeyp-113d7.1
si:dkeyp-113d7.1
chr4_-_12795030 1.53 ENSDART00000150427
b2m
beta-2-microglobulin
chr5_-_19014589 1.53 ENSDART00000002624
ranbp1
RAN binding protein 1
chr15_-_28805493 1.52 ENSDART00000179617
cd3eap
CD3e molecule, epsilon associated protein
chr11_+_18612421 1.52 ENSDART00000110621
ncoa3
nuclear receptor coactivator 3
chr11_+_14622379 1.51 ENSDART00000112589
efna2b
ephrin-A2b
chr6_+_43015916 1.51 ENSDART00000064888
tcta
T cell leukemia translocation altered
chr8_+_49065348 1.51 ENSDART00000032277
ddx51
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr2_+_26179096 1.50 ENSDART00000024662
plppr3a
phospholipid phosphatase related 3a
chr8_-_16712111 1.50 ENSDART00000184147
ENSDART00000180419
ENSDART00000076600
rpe65c
retinal pigment epithelium-specific protein 65c
chr17_-_21793113 1.50 ENSDART00000104612
hmx3a
H6 family homeobox 3a
chr25_-_10571078 1.49 ENSDART00000153898
si:ch211-107e6.5
si:ch211-107e6.5
chr24_+_9298198 1.49 ENSDART00000165780
otud1
OTU deubiquitinase 1
chr5_-_24231139 1.49 ENSDART00000143492
senp3a
SUMO1/sentrin/SMT3 specific peptidase 3a
chr16_-_21692024 1.49 ENSDART00000123597
si:ch211-154o6.2
si:ch211-154o6.2
chr20_-_2667902 1.47 ENSDART00000036373
cfap206
cilia and flagella associated protein 206
chr5_-_66749535 1.45 ENSDART00000132183
kat5b
K(lysine) acetyltransferase 5b
chr15_-_7337537 1.45 ENSDART00000161613
SLC7A1 (1 of many)
high affinity cationic amino acid transporter 1
chr5_+_29726428 1.44 ENSDART00000143183
ddx31
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr15_+_19990068 1.43 ENSDART00000154033
ENSDART00000054428
zgc:112083
zgc:112083
chr1_+_51537250 1.43 ENSDART00000152789
etaa1
ETAA1, ATR kinase activator
chr25_-_34740627 1.43 ENSDART00000137665
frs2b
fibroblast growth factor receptor substrate 2b
chr10_-_35186310 1.43 ENSDART00000127805
pom121
POM121 transmembrane nucleoporin
chr10_-_42237304 1.43 ENSDART00000140341
tcf7l1a
transcription factor 7 like 1a
chr7_-_24112484 1.42 ENSDART00000111923
ajuba
ajuba LIM protein
chr11_-_45420212 1.40 ENSDART00000182042
ENSDART00000163185
ankrd13c
ankyrin repeat domain 13C
chr19_+_18739085 1.39 ENSDART00000188868
spaca4l
sperm acrosome associated 4 like
chr19_-_25693728 1.38 ENSDART00000136187
bloc1s4
biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
chr7_+_26844261 1.37 ENSDART00000079165
ext2
exostosin glycosyltransferase 2
chr8_+_10305400 1.36 ENSDART00000172400
pim1
Pim-1 proto-oncogene, serine/threonine kinase
chr25_-_25142387 1.36 ENSDART00000031814
tsg101a
tumor susceptibility 101a
chr7_-_37555208 1.35 ENSDART00000148905
ENSDART00000150229
cylda
cylindromatosis (turban tumor syndrome), a
chr14_-_33425170 1.33 ENSDART00000124629
ENSDART00000105800
ENSDART00000001318
nkap
NFKB activating protein
chr21_+_25071805 1.33 ENSDART00000078651
dixdc1b
DIX domain containing 1b
chr16_-_41714988 1.32 ENSDART00000138798
cep85
centrosomal protein 85
chr1_+_45969240 1.32 ENSDART00000042086
arhgef7b
Rho guanine nucleotide exchange factor (GEF) 7b
chr14_-_34044369 1.30 ENSDART00000149396
ENSDART00000123607
ENSDART00000190746
cyfip2
cytoplasmic FMR1 interacting protein 2
chr19_-_46018152 1.29 ENSDART00000159206
krit1
KRIT1, ankyrin repeat containing
chr17_+_16755287 1.29 ENSDART00000080129
ston2
stonin 2
chr5_-_54672763 1.28 ENSDART00000159009
spag8
sperm associated antigen 8
chr21_-_28920245 1.28 ENSDART00000132884
cxxc5a
CXXC finger protein 5a
chr22_+_11153590 1.26 ENSDART00000188207
bcor
BCL6 corepressor
chr4_+_5868034 1.24 ENSDART00000166591
utp20
UTP20 small subunit (SSU) processome component
chr14_+_33264303 1.24 ENSDART00000130680
ENSDART00000075187
pdzd11
PDZ domain containing 11
chr10_+_28428222 1.23 ENSDART00000135003
si:ch211-222e20.4
si:ch211-222e20.4
chr12_-_8070969 1.23 ENSDART00000020995
tmem26b
transmembrane protein 26b
chr18_-_45761868 1.22 ENSDART00000025423
cstf3
cleavage stimulation factor, 3' pre-RNA, subunit 3
chr7_-_50367326 1.21 ENSDART00000141926
prc1b
protein regulator of cytokinesis 1b
chr12_+_28117365 1.21 ENSDART00000066290
UTS2R
urotensin 2 receptor
chr3_-_20793655 1.21 ENSDART00000163473
ENSDART00000159457
spop
speckle-type POZ protein
chr24_+_37640626 1.20 ENSDART00000008047
wdr24
WD repeat domain 24
chr7_+_52761841 1.19 ENSDART00000111444
ppip5k1a
diphosphoinositol pentakisphosphate kinase 1a
chr20_-_2641233 1.17 ENSDART00000145335
ENSDART00000133121
bub1
BUB1 mitotic checkpoint serine/threonine kinase
chr1_+_34295925 1.17 ENSDART00000075584
kctd12.2
potassium channel tetramerisation domain containing 12.2
chr21_-_30031396 1.17 ENSDART00000157167
pwwp2a
PWWP domain containing 2A
chr23_+_43424518 1.17 ENSDART00000022498
tti1
TELO2 interacting protein 1
chr4_+_11723852 1.17 ENSDART00000028820
mkln1
muskelin 1, intracellular mediator containing kelch motifs
chr14_-_21661015 1.16 ENSDART00000189403
ENSDART00000172442
ENSDART00000181913
kdm3b
lysine (K)-specific demethylase 3B
chr2_+_55365727 1.15 ENSDART00000162943
FP245456.1

chr21_+_17051478 1.13 ENSDART00000047201
ENSDART00000161650
ENSDART00000167298
atp2a2a
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr4_-_20135406 1.12 ENSDART00000161343
cep83
centrosomal protein 83
chr11_-_21586157 1.12 ENSDART00000190095
srgap2
SLIT-ROBO Rho GTPase activating protein 2
chr7_-_30127082 1.12 ENSDART00000173749
alpk3b
alpha-kinase 3b
chr5_+_36895860 1.12 ENSDART00000134493
srsf7a
serine/arginine-rich splicing factor 7a
chr7_+_56472585 1.11 ENSDART00000135259
ENSDART00000073596
ist1
increased sodium tolerance 1 homolog (yeast)
chr8_+_23147218 1.10 ENSDART00000030920
ENSDART00000141175
ENSDART00000146264
gid8a
GID complex subunit 8 homolog a (S. cerevisiae)
chr21_+_3796620 1.09 ENSDART00000099535
ENSDART00000144515
spout1
SPOUT domain containing methyltransferase 1
chr11_-_29563437 1.09 ENSDART00000163958
arhgef10la
Rho guanine nucleotide exchange factor (GEF) 10-like a
chr13_-_32906265 1.08 ENSDART00000113823
ENSDART00000171114
ENSDART00000180035
ENSDART00000137570
si:dkey-18j18.3
si:dkey-18j18.3
chr13_+_28690355 1.07 ENSDART00000137475
ENSDART00000128246
polr1c
polymerase (RNA) I polypeptide C
chr19_+_33476557 1.07 ENSDART00000181800
triqk
triple QxxK/R motif containing
chr20_+_53368611 1.07 ENSDART00000060432
cdc40
cell division cycle 40 homolog (S. cerevisiae)
chr25_+_28555584 1.07 ENSDART00000157046
SLC15A5
si:ch211-190o6.3
chr2_+_21982911 1.06 ENSDART00000190722
ENSDART00000044371
ENSDART00000134912
tox
thymocyte selection-associated high mobility group box
chr3_-_15475067 1.05 ENSDART00000025324
ENSDART00000139575
spns1
spinster homolog 1 (Drosophila)
chr8_+_23034718 1.04 ENSDART00000184512
ythdf1
YTH N(6)-methyladenosine RNA binding protein 1
chr23_+_25354856 1.04 ENSDART00000109023
ENSDART00000147440
fmnl3
formin-like 3
chr3_+_33440615 1.03 ENSDART00000146005
gtpbp1
GTP binding protein 1
chr24_+_14240196 1.03 ENSDART00000124740
ncoa2
nuclear receptor coactivator 2
chr22_+_39007533 1.03 ENSDART00000185958
ENSDART00000129848
fam208aa
family with sequence similarity 208, member Aa
chr25_+_3868438 1.03 ENSDART00000156438
tmem138
transmembrane protein 138
chr3_+_53116172 1.02 ENSDART00000115117
brd4
bromodomain containing 4
chr17_-_6451801 1.01 ENSDART00000064700
fuca2
alpha-L-fucosidase 2
chr1_+_35494837 0.99 ENSDART00000140724
gab1
GRB2-associated binding protein 1
chr24_+_27023616 0.99 ENSDART00000089541
dip2ca
disco-interacting protein 2 homolog Ca
chr23_-_42876596 0.99 ENSDART00000086156
dlgap4a
discs, large (Drosophila) homolog-associated protein 4a
chr10_+_22918338 0.99 ENSDART00000167874
ENSDART00000171298
zgc:103508
zgc:103508
chr12_-_10705916 0.98 ENSDART00000164038
FO704786.1

chr14_-_36799280 0.97 ENSDART00000168615
rnf130
ring finger protein 130
chr25_-_27843066 0.96 ENSDART00000179684
ENSDART00000186000
ENSDART00000190065
asb15a
ankyrin repeat and SOCS box containing 15a
chr9_+_52411530 0.95 ENSDART00000163684
nme8
NME/NM23 family member 8
chr19_+_619200 0.95 ENSDART00000050125
nupl2
nucleoporin like 2
chr15_-_4011013 0.94 ENSDART00000158029
CR626884.3

Network of associatons between targets according to the STRING database.

First level regulatory network of foxj1a+foxj1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.1 GO:0016108 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
1.1 2.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.9 6.0 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.8 3.4 GO:0071675 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675) positive regulation of lamellipodium organization(GO:1902745)
0.8 2.4 GO:1903373 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.8 2.3 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.7 2.2 GO:0061317 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.7 2.0 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.6 2.4 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.6 2.2 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.5 2.9 GO:0006004 fucose metabolic process(GO:0006004)
0.5 1.4 GO:2000637 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.4 1.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.4 2.2 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.4 1.3 GO:0045601 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.4 1.7 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.4 2.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.4 1.6 GO:2000583 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.4 1.6 GO:0051661 maintenance of centrosome location(GO:0051661)
0.4 1.4 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.3 1.0 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.3 1.7 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 3.2 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.3 1.5 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.3 0.9 GO:0051026 chiasma assembly(GO:0051026)
0.3 3.3 GO:0051256 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.3 1.8 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.3 2.0 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.3 1.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.3 2.8 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.3 3.3 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.3 1.6 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.3 2.1 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.3 3.1 GO:0042694 muscle cell fate specification(GO:0042694)
0.3 2.1 GO:0030656 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.3 0.8 GO:0090131 mesenchyme migration(GO:0090131)
0.3 4.8 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.2 1.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 1.5 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.2 4.6 GO:0046686 response to cadmium ion(GO:0046686)
0.2 2.4 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.2 2.6 GO:0046548 retinal rod cell development(GO:0046548)
0.2 1.4 GO:1990108 protein linear deubiquitination(GO:1990108)
0.2 1.1 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.2 0.7 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.2 0.4 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.2 0.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.2 1.7 GO:0021588 cerebellum formation(GO:0021588)
0.2 1.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 0.8 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.2 1.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 2.7 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.2 2.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.2 1.2 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.2 2.0 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.2 1.4 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2 3.2 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 1.4 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 0.7 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.1 4.3 GO:0043967 histone H4 acetylation(GO:0043967)
0.1 1.3 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.1 0.5 GO:1904182 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.1 3.5 GO:0008272 sulfate transport(GO:0008272)
0.1 0.9 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.4 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.1 2.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.6 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 0.4 GO:0030238 male sex determination(GO:0030238)
0.1 1.0 GO:0090398 cellular senescence(GO:0090398)
0.1 2.0 GO:0071456 cellular response to hypoxia(GO:0071456)
0.1 1.9 GO:0030316 osteoclast differentiation(GO:0030316)
0.1 0.3 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 3.9 GO:0007050 cell cycle arrest(GO:0007050)
0.1 1.9 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.9 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1 2.0 GO:0007032 endosome organization(GO:0007032)
0.1 1.8 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 1.2 GO:0006020 inositol metabolic process(GO:0006020)
0.1 2.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 2.0 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 1.0 GO:0061157 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.1 1.5 GO:0016926 protein desumoylation(GO:0016926)
0.1 3.4 GO:0032465 regulation of cytokinesis(GO:0032465)
0.1 1.5 GO:0015693 magnesium ion transport(GO:0015693)
0.1 2.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 1.3 GO:0001964 startle response(GO:0001964)
0.1 0.4 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 3.5 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 1.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 0.8 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 2.0 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1 0.5 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 1.8 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.1 1.0 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 1.4 GO:0007634 optokinetic behavior(GO:0007634)
0.1 0.3 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.6 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 1.8 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.5 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.2 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 1.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.7 GO:0030301 cholesterol transport(GO:0030301)
0.0 1.1 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.7 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 1.2 GO:0021986 habenula development(GO:0021986)
0.0 0.2 GO:0043091 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.0 2.1 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 0.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 1.4 GO:0039021 pronephric glomerulus development(GO:0039021)
0.0 0.8 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 1.8 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.4 GO:0070309 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.0 1.6 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.3 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.7 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.7 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.0 0.8 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.7 GO:0006027 glycosaminoglycan catabolic process(GO:0006027) sulfur compound catabolic process(GO:0044273)
0.0 1.6 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 2.0 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 1.2 GO:0031123 RNA 3'-end processing(GO:0031123)
0.0 1.0 GO:0046847 filopodium assembly(GO:0046847)
0.0 1.4 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 0.8 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.1 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.0 0.3 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.2 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 2.5 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 2.4 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 1.8 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.6 GO:0007286 spermatid development(GO:0007286)
0.0 1.1 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 1.5 GO:0048916 posterior lateral line development(GO:0048916)
0.0 0.9 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 3.9 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 1.0 GO:0006414 translational elongation(GO:0006414)
0.0 0.7 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 1.2 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.4 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.5 GO:0030199 collagen fibril organization(GO:0030199)
0.0 1.1 GO:0002521 leukocyte differentiation(GO:0002521)
0.0 0.8 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.8 2.4 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.6 1.9 GO:0034515 proteasome storage granule(GO:0034515)
0.5 1.5 GO:0001534 radial spoke(GO:0001534)
0.5 4.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.4 1.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.4 2.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.3 2.0 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 2.5 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.3 1.2 GO:0070209 ASTRA complex(GO:0070209)
0.3 2.0 GO:0005663 DNA replication factor C complex(GO:0005663)
0.3 3.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.3 0.8 GO:0005828 kinetochore microtubule(GO:0005828)
0.2 0.9 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 1.7 GO:0044232 organelle membrane contact site(GO:0044232)
0.2 1.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 2.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 0.8 GO:0017177 glucosidase II complex(GO:0017177)
0.2 1.0 GO:0016589 NURF complex(GO:0016589)
0.2 0.9 GO:0070695 FHF complex(GO:0070695)
0.1 3.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 2.2 GO:0071564 npBAF complex(GO:0071564)
0.1 1.6 GO:0017119 Golgi transport complex(GO:0017119)
0.1 2.4 GO:0045180 basal cortex(GO:0045180)
0.1 6.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.3 GO:0043218 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.1 0.9 GO:0032300 mismatch repair complex(GO:0032300)
0.1 1.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 4.1 GO:0072686 mitotic spindle(GO:0072686)
0.1 1.4 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.3 GO:0031209 SCAR complex(GO:0031209)
0.1 1.6 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 1.5 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 1.5 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 3.4 GO:0030496 midbody(GO:0030496)
0.1 1.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.6 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 0.3 GO:0016460 myosin II complex(GO:0016460)
0.1 0.4 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 3.8 GO:0005643 nuclear pore(GO:0005643)
0.1 4.3 GO:0005814 centriole(GO:0005814)
0.1 0.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.2 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 0.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 1.1 GO:0044327 dendritic spine head(GO:0044327)
0.1 2.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.8 GO:0005869 dynactin complex(GO:0005869)
0.0 1.2 GO:0030686 90S preribosome(GO:0030686)
0.0 1.4 GO:0043596 nuclear replication fork(GO:0043596)
0.0 2.0 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0060170 ciliary membrane(GO:0060170)
0.0 4.6 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 3.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 1.4 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 3.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 7.0 GO:0005730 nucleolus(GO:0005730)
0.0 1.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.0 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 1.8 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 2.1 GO:0005795 Golgi stack(GO:0005795)
0.0 0.5 GO:0043195 terminal bouton(GO:0043195)
0.0 1.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0045495 pole plasm(GO:0045495)
0.0 2.2 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 2.0 GO:0005819 spindle(GO:0005819)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 2.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.4 GO:0016607 nuclear speck(GO:0016607)
0.0 4.4 GO:0000785 chromatin(GO:0000785)
0.0 0.1 GO:0097268 cytoophidium(GO:0097268)
0.0 0.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.0 GO:0000793 condensed chromosome(GO:0000793)
0.0 3.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.2 GO:0030141 secretory granule(GO:0030141)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.0 GO:0005759 mitochondrial matrix(GO:0005759)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.1 GO:0050251 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.9 6.0 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.8 2.4 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.8 2.3 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.5 2.0 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.5 3.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.4 2.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.4 1.2 GO:0008022 protein C-terminus binding(GO:0008022)
0.4 4.8 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.3 2.1 GO:0015616 DNA translocase activity(GO:0015616)
0.3 1.0 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.3 2.2 GO:0070888 E-box binding(GO:0070888)
0.3 1.2 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.3 2.0 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.3 2.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.3 1.4 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.3 1.9 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 1.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 3.9 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.2 2.0 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 1.0 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.2 2.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 3.5 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.2 1.6 GO:0035198 miRNA binding(GO:0035198)
0.2 3.2 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 0.5 GO:0047453 ATP-dependent NAD(P)H-hydrate dehydratase activity(GO:0047453) ADP-dependent NAD(P)H-hydrate dehydratase activity(GO:0052855)
0.1 0.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 2.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.9 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 2.4 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.7 GO:1903924 estradiol binding(GO:1903924)
0.1 1.9 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 2.7 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 1.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 5.4 GO:0008013 beta-catenin binding(GO:0008013)
0.1 2.8 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 1.5 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 1.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 1.8 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.8 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 1.6 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1 2.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.9 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 1.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 1.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 2.2 GO:0030165 PDZ domain binding(GO:0030165)
0.1 1.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.2 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.1 5.7 GO:0003724 RNA helicase activity(GO:0003724)
0.1 1.5 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 1.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.3 GO:0032034 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.1 0.4 GO:0004738 pyruvate dehydrogenase activity(GO:0004738)
0.1 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.2 GO:0051380 norepinephrine binding(GO:0051380)
0.1 4.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 3.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 1.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 3.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.4 GO:0001727 lipid kinase activity(GO:0001727)
0.1 2.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 3.9 GO:0003678 DNA helicase activity(GO:0003678)
0.1 0.9 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 1.1 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.5 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 1.1 GO:0004675 transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.0 0.4 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.7 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 1.3 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 2.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 3.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 4.5 GO:0000989 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 0.5 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 1.2 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.4 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 5.2 GO:0008017 microtubule binding(GO:0008017)
0.0 1.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.6 GO:0004521 endoribonuclease activity(GO:0004521)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 3.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 8.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.2 2.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 7.4 PID PLK1 PATHWAY PLK1 signaling events
0.1 2.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 2.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 1.4 PID IL5 PATHWAY IL5-mediated signaling events
0.1 1.0 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 2.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 1.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 1.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 1.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 2.0 PID ATR PATHWAY ATR signaling pathway
0.0 1.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.8 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 2.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.8 PID INSULIN PATHWAY Insulin Pathway
0.0 0.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 3.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 2.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.4 2.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.2 2.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 3.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 2.1 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 3.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 2.0 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.1 1.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 2.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 0.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.8 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 1.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.1 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 6.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 0.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 2.3 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 0.7 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 2.4 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.8 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.9 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 1.0 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.5 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.7 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.9 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane