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PRJEB1986: zebrafish developmental stages transcriptome

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Results for foxj2

Z-value: 0.67

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Transcription factors associated with foxj2

Gene Symbol Gene ID Gene Info
ENSDARG00000057680 forkhead box J2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxj2dr11_v1_chr16_-_12784373_12784373-0.831.1e-05Click!

Activity profile of foxj2 motif

Sorted Z-values of foxj2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_24201437 2.44 ENSDART00000114113
SRY (sex determining region Y)-box 19a
chr7_-_17337233 2.41 ENSDART00000050236
ENSDART00000102141
novel immune-type receptor 8
chr23_+_32335871 1.88 ENSDART00000149698
solute carrier family 39 (zinc transporter), member 5
chr16_+_54210554 1.81 ENSDART00000172622
X-ray repair complementing defective repair in Chinese hamster cells 1
chr7_-_54679595 1.79 ENSDART00000165320
cyclin D1
chr10_-_35257458 1.72 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr14_+_20911310 1.63 ENSDART00000160318
lysozyme g-like 2
chr11_+_37768298 1.62 ENSDART00000166886
SRY (sex determining region Y)-box 13
chr16_-_6198543 1.57 ENSDART00000167505
catenin (cadherin-associated protein), beta 1
chr19_-_1948236 1.48 ENSDART00000163344
zinc and ring finger 2a
chr20_+_25904199 1.41 ENSDART00000016864
solute carrier family 35, member F6
chr25_-_19608382 1.28 ENSDART00000022279
ENSDART00000135201
ENSDART00000147223
ENSDART00000190220
ENSDART00000184242
ENSDART00000166824
G-2 and S-phase expressed 1
chr17_+_51743908 1.18 ENSDART00000149039
ENSDART00000148869
ornithine decarboxylase 1
chr4_+_21741228 1.16 ENSDART00000112035
ENSDART00000127664
myogenic factor 5
chr19_-_2318391 1.14 ENSDART00000012791
sp8 transcription factor a
chr3_-_58644920 1.12 ENSDART00000155953
dehydrogenase/reductase (SDR family) member 7Ca
chr20_+_34770197 1.12 ENSDART00000018304
minichromosome maintenance complex component 3
chr12_-_17479078 1.11 ENSDART00000079115
3'-phosphoadenosine 5'-phosphosulfate synthase 2b
chr17_+_15534815 1.10 ENSDART00000159426
myristoylated alanine-rich protein kinase C substrate b
chr2_-_29996036 1.02 ENSDART00000020792
canopy1
chr7_+_67434677 1.01 ENSDART00000165971
ENSDART00000166702
lysyl-tRNA synthetase
chr18_-_44316920 0.98 ENSDART00000098599
si:ch211-151h10.2
chr7_-_20464468 0.97 ENSDART00000134700
canopy4
chr23_-_27607039 0.96 ENSDART00000183639
PHD finger protein 8
chr10_+_15025006 0.95 ENSDART00000145192
ENSDART00000140084
si:dkey-88l16.5
chr19_+_6990970 0.94 ENSDART00000158758
ENSDART00000160482
ENSDART00000193566
kinesin family member C1
chr4_+_17353714 0.92 ENSDART00000136299
nucleoporin 37
chr3_-_44094451 0.92 ENSDART00000157902
ENSDART00000190036
ENSDART00000188028
lysine (K)-specific demethylase 8
chr2_+_30480907 0.91 ENSDART00000041378
ENSDART00000138863
family with sequence similarity 173, member B
chr3_+_34159192 0.89 ENSDART00000151119
coactivator-associated arginine methyltransferase 1
chr24_+_21540842 0.89 ENSDART00000091529
WAS protein family, member 3b
chr18_+_20034023 0.86 ENSDART00000139441
mortality factor 4 like 1
chr18_-_15911394 0.84 ENSDART00000091339
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr19_+_41551335 0.84 ENSDART00000169193
si:ch211-57n23.4
chr3_-_44094248 0.82 ENSDART00000166866
lysine (K)-specific demethylase 8
chr19_+_20177887 0.82 ENSDART00000008595
transformer 2 alpha homolog
chr25_-_13789955 0.82 ENSDART00000167742
ENSDART00000165116
ENSDART00000171461
cytoskeleton associated protein 5
chr3_-_55328548 0.82 ENSDART00000082944
dedicator of cytokinesis 6
chr18_+_25225524 0.80 ENSDART00000055563
si:dkeyp-59c12.1
chr10_+_42898103 0.79 ENSDART00000015872
zinc finger, CCHC domain containing 9
chr18_-_24988645 0.79 ENSDART00000136434
ENSDART00000085735
chromodomain helicase DNA binding protein 2
chr17_+_38602790 0.78 ENSDART00000062010
coiled-coil domain containing 88C
chr8_+_23147609 0.78 ENSDART00000180284
GID complex subunit 8 homolog a (S. cerevisiae)
chr13_-_10431476 0.77 ENSDART00000133968
calmodulin-lysine N-methyltransferase
chr2_+_22602301 0.76 ENSDART00000038514
septin 2
chr15_-_5901514 0.76 ENSDART00000155252
si:ch73-281n10.2
chr4_-_2265271 0.76 ENSDART00000125815
KRR1, small subunit (SSU) processome component, homolog (yeast)
chr4_+_56974252 0.74 ENSDART00000161888
zinc finger protein 999
chr3_+_13862753 0.74 ENSDART00000168315
interleukin enhancer binding factor 3b
chr4_-_12795030 0.73 ENSDART00000150427
beta-2-microglobulin
chr5_+_63302660 0.72 ENSDART00000142131
si:ch73-376l24.2
chr8_+_31016180 0.72 ENSDART00000130870
ENSDART00000143604
outer dense fiber of sperm tails 2b
chr17_+_5985933 0.72 ENSDART00000190844
zgc:194275
chr3_-_62194512 0.72 ENSDART00000074174
transducin (beta)-like 3
chr11_-_22372072 0.72 ENSDART00000065996
transmembrane protein 183A
chr15_+_21254800 0.72 ENSDART00000142902
upstream transcription factor 1
chr12_+_11352630 0.71 ENSDART00000129495
si:rp71-19m20.1
chr10_+_35257651 0.70 ENSDART00000028940
serine/threonine/tyrosine interacting-like 1
chr17_-_28797395 0.68 ENSDART00000134735
sec1 family domain containing 1
chr7_-_28549361 0.68 ENSDART00000173918
ENSDART00000054368
ENSDART00000113313
suppression of tumorigenicity 5
chr8_+_48942470 0.67 ENSDART00000005464
ENSDART00000132035
retention in endoplasmic reticulum sorting receptor 1
chr3_+_28860283 0.67 ENSDART00000077235
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr13_+_39315881 0.67 ENSDART00000135999
si:dkey-85a20.4
chr5_-_63302944 0.66 ENSDART00000047110
gelsolin b
chr6_-_7439490 0.66 ENSDART00000188825
FK506 binding protein 11
chr3_-_57762247 0.65 ENSDART00000156522
calcium activated nucleotidase 1a
chr13_+_47007075 0.65 ENSDART00000109247
ENSDART00000183205
ENSDART00000180924
ENSDART00000133146
anaphase promoting complex subunit 1
chr13_-_31687925 0.64 ENSDART00000085989
TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
chr2_+_29996650 0.64 ENSDART00000138050
ENSDART00000141026
RNA binding motif protein 33b
chr12_+_5977777 0.62 ENSDART00000152302
si:ch211-131k2.2
chr1_-_36770883 0.62 ENSDART00000167831
protein arginine methyltransferase 9
chr25_+_3217419 0.61 ENSDART00000104859
RCC1 domain containing 1
chr6_-_40449399 0.61 ENSDART00000103879
TatD DNase domain containing 2
chr1_-_14503182 0.60 ENSDART00000190599
si:dkey-194g4.1
chr23_-_17450746 0.60 ENSDART00000145399
ENSDART00000136457
ENSDART00000133125
ENSDART00000145719
ENSDART00000147524
ENSDART00000005366
ENSDART00000104680
tumor protein D52-like 2b
chr1_+_53945934 0.59 ENSDART00000052838
actin, alpha 1a, skeletal muscle
chr2_-_30668580 0.58 ENSDART00000087270
catenin (cadherin-associated protein), delta 2b
chr5_+_42957503 0.58 ENSDART00000192885
MOB kinase activator 1Ba
chr8_+_40284973 0.58 ENSDART00000018401
ORAI calcium release-activated calcium modulator 1a
chr4_+_27100531 0.58 ENSDART00000115200
ALG12, alpha-1,6-mannosyltransferase
chr4_+_13586455 0.57 ENSDART00000187230
transportin 3
chr25_+_14870043 0.57 ENSDART00000035714
ENSDART00000171835
DnaJ (Hsp40) homolog, subfamily C, member 24
chr1_-_23268013 0.57 ENSDART00000146575
replication factor C (activator 1) 1
chr15_+_30126971 0.56 ENSDART00000100214
nuclear fragile X mental retardation protein interacting protein 2
chr10_-_13178853 0.56 ENSDART00000163740
ENSDART00000166327
ENSDART00000160265
ENSDART00000164299
muscle, skeletal, receptor tyrosine kinase
chr18_+_14633974 0.56 ENSDART00000133834
VPS9 domain containing 1
chr15_-_9002155 0.55 ENSDART00000126708
ras homolog family member Ub
chr23_+_45966436 0.55 ENSDART00000172160

chr10_+_17681074 0.55 ENSDART00000057500
developmentally regulated GTP binding protein 1
chr25_-_3217115 0.54 ENSDART00000032390
general transcription factor IIH, polypeptide 1
chr5_+_29726428 0.54 ENSDART00000143183
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr8_+_10305400 0.54 ENSDART00000172400
Pim-1 proto-oncogene, serine/threonine kinase
chr19_+_48018802 0.53 ENSDART00000161339
ENSDART00000166978
si:ch1073-205c8.3
chr21_-_11199366 0.52 ENSDART00000167666
DnaJ (Hsp40) homolog, subfamily C, member 21
chr23_+_20640875 0.52 ENSDART00000147382
ubiquitin-like modifier activating enzyme 1
chr4_+_71819777 0.52 ENSDART00000171070
zinc finger protein 1017
chr4_+_50891961 0.51 ENSDART00000150271
si:ch211-208f21.2
chr14_+_35279343 0.51 ENSDART00000187750
clathrin interactor 1a
chr8_-_41264502 0.49 ENSDART00000133124
ring finger protein 10
chr22_-_36875264 0.49 ENSDART00000137548
kininogen 1
chr1_-_26444075 0.49 ENSDART00000125690
integrator complex subunit 12
chr16_+_45922175 0.48 ENSDART00000018253
RNA binding motif protein 8A
chr13_-_25476920 0.47 ENSDART00000131403
TIA1 cytotoxic granule-associated RNA binding protein-like 1
chr1_-_55166511 0.47 ENSDART00000150430
ENSDART00000035725
proliferation associated nuclear element
chr19_+_41551543 0.46 ENSDART00000112364
si:ch211-57n23.4
chr11_-_45420212 0.46 ENSDART00000182042
ENSDART00000163185
ankyrin repeat domain 13C
chr22_+_2170887 0.46 ENSDART00000147881
ENSDART00000169375
ENSDART00000165871
ENSDART00000166014
zinc finger protein 1151
chr12_-_9790485 0.46 ENSDART00000027321
PR domain containing 9
chr17_+_24597001 0.46 ENSDART00000191834
rearranged L-myc fusion
chr16_+_26777473 0.44 ENSDART00000188870
cadherin 17, LI cadherin (liver-intestine)
chr20_+_33924235 0.44 ENSDART00000146292
ENSDART00000139609
LIM homeobox transcription factor 1, alpha
chr19_+_18739085 0.43 ENSDART00000188868
sperm acrosome associated 4 like
chr14_+_16151636 0.43 ENSDART00000159352
polymerase (RNA) I polypeptide A
chr12_+_28799988 0.41 ENSDART00000022724
pyridoxamine 5'-phosphate oxidase
chr4_-_12795436 0.41 ENSDART00000131026
ENSDART00000075127
beta-2-microglobulin
chr2_+_48303142 0.41 ENSDART00000023040
hes family bHLH transcription factor 6
chr15_+_42573909 0.39 ENSDART00000181801
zgc:110333
chr13_-_36319308 0.39 ENSDART00000057164
COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
chr19_+_4856351 0.39 ENSDART00000093402
cyclin-dependent kinase 12
chr3_-_29891218 0.39 ENSDART00000142118
solute carrier family 25, member 39
chr22_+_4442473 0.39 ENSDART00000170751
toll-like receptor adaptor molecule 1
chr2_+_20410652 0.37 ENSDART00000185940
palmdelphin a
chr11_-_11878099 0.37 ENSDART00000188314
WAS/WASL interacting protein family, member 2a
chr15_+_32419303 0.37 ENSDART00000162663
si:dkey-285b23.3
chr4_+_14727212 0.37 ENSDART00000158094
cytidine monophosphate N-acetylneuraminic acid synthetase a
chr8_-_43750062 0.36 ENSDART00000142243
unc-51 like autophagy activating kinase 1a
chr13_-_15986871 0.36 ENSDART00000189394
IKAROS family zinc finger 1 (Ikaros)
chr11_-_16394971 0.36 ENSDART00000180981
ENSDART00000179925
leucine-rich repeats and immunoglobulin-like domains 1
chr24_+_17345521 0.36 ENSDART00000024722
ENSDART00000154250
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr17_+_16755287 0.36 ENSDART00000080129
stonin 2
chr15_-_18574716 0.35 ENSDART00000142010
ENSDART00000019006
neural cell adhesion molecule 1b
chr18_-_17721810 0.35 ENSDART00000061016
family with sequence similarity 192, member A
chr19_+_19767567 0.35 ENSDART00000169074
homeobox A3a
chr10_-_15672862 0.35 ENSDART00000109231
MAM domain containing 2b
chr14_-_34633960 0.33 ENSDART00000128869
ENSDART00000179977
actin filament associated protein 1-like 1a
chr25_+_150570 0.33 ENSDART00000170892
ADAM metallopeptidase domain 10b
chr8_-_51954562 0.33 ENSDART00000132527
ENSDART00000057315
centrosomal protein 78
chr17_+_11372531 0.32 ENSDART00000130975
ENSDART00000149366
translocase of inner mitochondrial membrane 9 homolog
chr23_-_7594723 0.32 ENSDART00000115298
pleiomorphic adenoma gene-like 2
chr16_-_41714988 0.31 ENSDART00000138798
centrosomal protein 85
chr3_+_17878124 0.31 ENSDART00000166430
ENSDART00000163421
ENSDART00000121473
DnaJ (Hsp40) homolog, subfamily C, member 7
chr4_+_13586689 0.30 ENSDART00000067161
ENSDART00000138201
transportin 3
chr16_+_10422836 0.30 ENSDART00000161568
INO80 complex subunit E
chr15_-_617797 0.29 ENSDART00000154224
si:ch73-144d13.7
chr8_-_46457233 0.29 ENSDART00000113214
sulfotransferase family 1, cytosolic sulfotransferase 7
chr25_+_25310063 0.29 ENSDART00000164291

chr25_+_28563465 0.29 ENSDART00000186861
si:ch211-190o6.3
chr14_+_21699129 0.29 ENSDART00000073707
syntaxin 3A
chr17_-_29119362 0.28 ENSDART00000104204
forkhead box G1a
chr16_-_17560822 0.28 ENSDART00000089230
caspase 2, apoptosis-related cysteine peptidase
chr19_+_48018464 0.28 ENSDART00000172307
ENSDART00000163848
si:ch1073-205c8.3
chr21_-_34261677 0.28 ENSDART00000124649
ENSDART00000172381
ENSDART00000064320
ALG13, UDP-N-acetylglucosaminyltransferase subunit
chr1_+_40566978 0.28 ENSDART00000137047
ENSDART00000135578
short coiled-coil protein a
chr5_+_53009083 0.27 ENSDART00000157836
histidine triad nucleotide binding protein 2
chr8_+_20918207 0.27 ENSDART00000144039
si:ch73-196i15.5
chr3_-_14571514 0.26 ENSDART00000137197
SWIM-type zinc finger 7 associated protein 1
chr15_+_618081 0.25 ENSDART00000181518
si:ch211-210b2.1
chr4_+_45148652 0.25 ENSDART00000150798
si:dkey-51d8.9
chr19_-_35492693 0.24 ENSDART00000135838
ENSDART00000051745
ENSDART00000177052
protein tyrosine phosphatase type IVA, member 2b
chr6_-_14004772 0.24 ENSDART00000185629
zgc:92027
chr8_-_11202378 0.24 ENSDART00000147817
ENSDART00000174039
family with sequence similarity 208, member B
chr17_+_6957042 0.23 ENSDART00000103839
zgc:172341
chr6_-_18393476 0.23 ENSDART00000168309
tripartite motif containing 25
chr6_-_2171818 0.23 ENSDART00000181082
ENSDART00000187556
wu:fe02h09
chr3_-_29891456 0.22 ENSDART00000151677
ENSDART00000014021
solute carrier family 25, member 39
chr5_+_46277593 0.22 ENSDART00000045598
zgc:110626
chr25_+_16689633 0.22 ENSDART00000073416
adenosine deaminase 2a
chr16_-_47360023 0.21 ENSDART00000164041
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
chr14_+_16151368 0.21 ENSDART00000160973
polymerase (RNA) I polypeptide A
chr3_-_31893008 0.21 ENSDART00000127297
DEAD (Asp-Glu-Ala-Asp) box helicase 42
chr25_-_6261693 0.20 ENSDART00000135808
iron-responsive element binding protein 2
chr21_+_38732945 0.20 ENSDART00000076157
RAB24, member RAS oncogene family
chr8_+_17838924 0.19 ENSDART00000170762
solute carrier family 44, member 5b
chr20_-_33966148 0.19 ENSDART00000148111
selectin P
chr10_-_36253958 0.19 ENSDART00000126288
odorant receptor, family D, subfamily 110, member 2
chr1_-_29761086 0.19 ENSDART00000136760
asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase)
chr22_+_15624371 0.19 ENSDART00000124868
lipoprotein lipase
chr19_-_15229421 0.19 ENSDART00000055619
phosphatase and actin regulator 4a
chr18_+_41561285 0.19 ENSDART00000169621
bromodomain adjacent to zinc finger domain, 1B
chr19_+_46222918 0.18 ENSDART00000158703
vacuolar protein sorting 28 (yeast)
chr22_+_36875400 0.18 ENSDART00000158293
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr7_+_5920665 0.17 ENSDART00000173208
si:dkey-23a13.11
chr1_+_17527931 0.17 ENSDART00000131927
caspase 3, apoptosis-related cysteine peptidase a
chr19_-_25119443 0.17 ENSDART00000148953
protein tyrosine phosphatase type IVA, member 3
chr1_+_16127825 0.17 ENSDART00000122503
tumor suppressor candidate 3
chr5_-_69212184 0.17 ENSDART00000053963
methionine adenosyltransferase II, alpha b
chr20_-_3390406 0.16 ENSDART00000136987
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr18_+_38885309 0.16 ENSDART00000041597
cAMP-regulated phosphoprotein 19a
chr2_-_38337122 0.15 ENSDART00000076523
ENSDART00000187473
solute carrier family 7 (amino acid transporter light chain, L system), member 8b
chr15_-_17870090 0.15 ENSDART00000155066
activating transcription factor 5b
chr24_-_27430612 0.15 ENSDART00000158139

chr12_+_4149112 0.14 ENSDART00000166191
integrin, alpha M (complement component 3 receptor 3 subunit)
chr6_+_12527725 0.14 ENSDART00000149328
serine/threonine kinase 24b (STE20 homolog, yeast)
chr15_+_31444466 0.13 ENSDART00000143003
odorant receptor, family C, subfamily 103, member 4
chr18_+_35742838 0.13 ENSDART00000088504
ENSDART00000140386
RAS guanyl releasing protein 4
chr25_+_17920361 0.13 ENSDART00000185644
BLOC-1 related complex subunit 5
chr8_+_23521974 0.13 ENSDART00000188130
ENSDART00000129378
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr7_+_37372479 0.13 ENSDART00000173652
spalt-like transcription factor 1a
chr7_-_59047720 0.13 ENSDART00000184831

chr15_+_5901970 0.12 ENSDART00000114134
tryptophan rich basic protein

Network of associatons between targets according to the STRING database.

First level regulatory network of foxj2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.5 1.6 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.4 1.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.4 1.1 GO:0034036 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.4 1.8 GO:0000012 single strand break repair(GO:0000012)
0.4 1.8 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.3 1.7 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.3 1.0 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.2 0.7 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.2 0.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.2 0.9 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 1.9 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.2 0.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 0.6 GO:0090131 mesenchyme migration(GO:0090131)
0.2 0.7 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.2 1.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 0.6 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.2 1.1 GO:1902292 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.2 1.4 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.2 0.6 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.2 0.5 GO:0080182 histone H3-K4 trimethylation(GO:0080182) histone H3-K36 dimethylation(GO:0097676)
0.1 0.4 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 1.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.4 GO:0035666 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.1 1.9 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.1 0.9 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 1.1 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122) negative regulation of innate immune response(GO:0045824)
0.1 0.2 GO:0039535 RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535)
0.1 0.6 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 0.5 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 0.9 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.5 GO:0031643 positive regulation of myelination(GO:0031643)
0.1 0.6 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.1 0.4 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 0.9 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.6 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.1 0.2 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.7 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 0.4 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.6 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0006154 adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.0 0.6 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 1.7 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.2 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.3 GO:0043584 nose development(GO:0043584)
0.0 0.6 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.5 GO:0045682 regulation of epidermis development(GO:0045682)
0.0 0.3 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.2 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.0 0.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.7 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.6 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.0 0.7 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.2 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.9 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 0.1 GO:0048909 anterior lateral line nerve development(GO:0048909) anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.0 0.7 GO:0051014 actin filament severing(GO:0051014)
0.0 0.7 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.6 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 1.2 GO:0030217 T cell differentiation(GO:0030217)
0.0 0.5 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 1.1 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.4 GO:0007286 spermatid development(GO:0007286)
0.0 0.3 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.7 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.0 GO:0090199 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.7 GO:0051607 defense response to virus(GO:0051607)
0.0 0.2 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.1 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.0 2.4 GO:0009617 response to bacterium(GO:0009617)
0.0 0.1 GO:0001709 cell fate determination(GO:0001709)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.2 1.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.9 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.5 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 0.5 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.7 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.1 GO:0042555 MCM complex(GO:0042555)
0.1 2.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.6 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.9 GO:0031209 SCAR complex(GO:0031209)
0.1 0.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.4 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 1.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.8 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.8 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.3 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.1 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.9 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 3.5 GO:0005730 nucleolus(GO:0005730)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.5 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0003796 lysozyme activity(GO:0003796)
0.4 1.1 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2 1.0 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.2 0.7 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 0.9 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.2 1.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 1.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.2 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.1 0.6 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.3 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.1 0.6 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.6 GO:0016530 metallochaperone activity(GO:0016530)
0.1 0.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.7 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.2 GO:0003994 aconitate hydratase activity(GO:0003994)
0.1 0.2 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.1 0.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.2 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 0.7 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 1.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 1.8 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.0 0.4 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.4 GO:0030332 cyclin binding(GO:0030332)
0.0 0.7 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 1.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0043394 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.0 0.6 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 1.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.6 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.4 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.4 GO:0010181 FMN binding(GO:0010181)
0.0 0.6 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 1.1 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.4 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.3 GO:0004675 transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.0 0.8 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling
0.0 0.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.6 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.8 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.1 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.3 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 1.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.8 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 1.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 1.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.0 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.6 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination