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PRJEB1986: zebrafish developmental stages transcriptome

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Results for foxl1

Z-value: 1.41

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Transcription factors associated with foxl1

Gene Symbol Gene ID Gene Info
foxl1
ENSDARG00000008133 forkhead box L1
foxl1
ENSDARG00000111418 forkhead box L1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxl1dr11_v1_chr18_-_17485419_17485419-0.633.5e-03Click!

Activity profile of foxl1 motif

Sorted Z-values of foxl1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_306036 6.59 ENSDART00000103659
msgn1
mesogenin 1
chr19_-_41518922 4.76 ENSDART00000164483
ENSDART00000062080
chrac1
chromatin accessibility complex 1
chr12_-_16898140 4.71 ENSDART00000152656
MGC174155
Cathepsin L1-like
chr12_-_16720432 3.95 ENSDART00000152261
ENSDART00000152154
si:dkey-26g8.4
si:dkey-26g8.4
chr8_-_50259448 3.33 ENSDART00000146056
nkx3-1
NK3 homeobox 1
chr20_-_34711528 3.06 ENSDART00000061555
si:ch211-63o20.7
si:ch211-63o20.7
chr16_-_27566552 3.04 ENSDART00000142102
zgc:153215
zgc:153215
chr11_+_41981959 2.97 ENSDART00000055707
her15.1
hairy and enhancer of split-related 15, tandem duplicate 1
chr4_+_5868034 2.94 ENSDART00000166591
utp20
UTP20 small subunit (SSU) processome component
chr13_-_24260609 2.93 ENSDART00000138747
urb2
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr7_-_71585065 2.74 ENSDART00000128678
mettl4
methyltransferase like 4
chr22_+_13977772 2.73 ENSDART00000080313
arl4ca
ADP-ribosylation factor-like 4Ca
chr18_+_20034023 2.58 ENSDART00000139441
morf4l1
mortality factor 4 like 1
chr17_+_25331576 2.29 ENSDART00000157309
tmem54a
transmembrane protein 54a
chr12_-_17698517 2.23 ENSDART00000105974
pvalb9
parvalbumin 9
chr2_+_29996650 2.19 ENSDART00000138050
ENSDART00000141026
rbm33b
RNA binding motif protein 33b
chr3_-_9444749 2.17 ENSDART00000182191
FO904885.3

chr5_-_3574199 2.16 ENSDART00000060162
hspb1
heat shock protein, alpha-crystallin-related, 1
chr11_-_10456553 2.13 ENSDART00000169509
ENSDART00000185574
ENSDART00000188276
ect2
epithelial cell transforming 2
chr17_+_38447473 2.12 ENSDART00000149007
cdan1
codanin 1
chr23_-_36934944 2.08 ENSDART00000109976
ENSDART00000162179
acap3a
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3a
chr5_+_65086856 2.02 ENSDART00000169209
ENSDART00000162409
ptrh1
peptidyl-tRNA hydrolase 1 homolog
chr12_-_17698669 2.02 ENSDART00000191384
pvalb9
parvalbumin 9
chr15_-_23529945 2.01 ENSDART00000152543
hmbsb
hydroxymethylbilane synthase, b
chr23_+_21473103 1.99 ENSDART00000142921
si:ch73-21g5.7
si:ch73-21g5.7
chr14_+_989733 1.95 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
si:ch73-308l14.2
chr15_-_16384184 1.88 ENSDART00000154504
fam222bb
family with sequence similarity 222, member Bb
chr3_-_16719244 1.88 ENSDART00000055859
pold1
polymerase (DNA directed), delta 1, catalytic subunit
chr21_-_37194669 1.81 ENSDART00000192748
fgfr4
fibroblast growth factor receptor 4
chr8_+_28259347 1.79 ENSDART00000110857
fam212b
family with sequence similarity 212, member B
chr24_+_22485710 1.78 ENSDART00000146058
si:dkey-40h20.1
si:dkey-40h20.1
chr19_+_7835025 1.78 ENSDART00000026276
cks1b
CDC28 protein kinase regulatory subunit 1B
chr22_+_1911269 1.78 ENSDART00000164158
ENSDART00000168205
znf1156
zinc finger protein 1156
chr3_-_20118342 1.77 ENSDART00000139902
selenow2a
selenoprotein W, 2a
chr12_+_19348538 1.75 ENSDART00000066388
tomm22
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr13_-_31296358 1.72 ENSDART00000030946
prdm8
PR domain containing 8
chr7_-_44970682 1.71 ENSDART00000144591
fam96b
family with sequence similarity 96, member B
chr24_-_21090447 1.70 ENSDART00000136507
ENSDART00000140786
ENSDART00000184841
qtrt2
queuine tRNA-ribosyltransferase accessory subunit 2
chr19_-_11315224 1.70 ENSDART00000104933
eepd1
endonuclease/exonuclease/phosphatase family domain containing 1
chr3_-_16289826 1.69 ENSDART00000131972
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr6_-_9646275 1.69 ENSDART00000012903
wdr12
WD repeat domain 12
chr22_+_9918872 1.66 ENSDART00000177953
blf
bloody fingers
chr11_-_27702778 1.65 ENSDART00000045942
ENSDART00000125352
phf2
PHD finger protein 2
chr22_+_18315490 1.63 ENSDART00000160413
gatad2ab
GATA zinc finger domain containing 2Ab
chr7_+_67429185 1.58 ENSDART00000162553
ENSDART00000178646
kars
lysyl-tRNA synthetase
chr18_-_27316599 1.55 ENSDART00000028294
zgc:56106
zgc:56106
chr12_-_48188928 1.55 ENSDART00000184384
pald1a
phosphatase domain containing, paladin 1a
chr23_+_25292147 1.55 ENSDART00000131486
pa2g4b
proliferation-associated 2G4, b
chr2_-_23391266 1.54 ENSDART00000159048
ivns1abpb
influenza virus NS1A binding protein b
chr11_-_25418856 1.53 ENSDART00000013714
gata1a
GATA binding protein 1a
chr12_+_27231212 1.53 ENSDART00000133023
ENSDART00000123739
tmem106a
transmembrane protein 106A
chr25_-_11026907 1.52 ENSDART00000156846
mespbb
mesoderm posterior bb
chr21_+_3796196 1.51 ENSDART00000146754
spout1
SPOUT domain containing methyltransferase 1
chr6_-_39275793 1.50 ENSDART00000180477
ENSDART00000148531
arhgef25b
Rho guanine nucleotide exchange factor (GEF) 25b
chr19_+_16015881 1.50 ENSDART00000187135
ctps1a
CTP synthase 1a
chr1_+_580642 1.50 ENSDART00000147633
mrpl39
mitochondrial ribosomal protein L39
chr5_+_1493767 1.48 ENSDART00000022132
haus4
HAUS augmin-like complex, subunit 4
chr7_-_64971839 1.46 ENSDART00000164682
sinhcafl
SIN3-HDAC complex associated factor, like
chr6_+_3816241 1.45 ENSDART00000178545
erich2
glutamate-rich 2
chr6_+_28124393 1.43 ENSDART00000089195
gpr17
G protein-coupled receptor 17
chr25_-_10630496 1.42 ENSDART00000153639
ENSDART00000181722
ENSDART00000177834
ppp6r3
protein phosphatase 6, regulatory subunit 3
chr23_-_36439961 1.42 ENSDART00000187907
csad
cysteine sulfinic acid decarboxylase
chr15_-_17406056 1.41 ENSDART00000146735
tubd1
tubulin, delta 1
chr23_+_45027263 1.40 ENSDART00000058364
hmgb2b
high mobility group box 2b
chr21_-_37194839 1.39 ENSDART00000175126
fgfr4
fibroblast growth factor receptor 4
chr15_-_31514818 1.37 ENSDART00000153978
hmgb1b
high mobility group box 1b
chr4_+_59320243 1.37 ENSDART00000150611
znf1084
zinc finger protein 1084
chr13_+_11436130 1.37 ENSDART00000169895
zbtb18
zinc finger and BTB domain containing 18
chr6_-_50685862 1.36 ENSDART00000134146
mtss1
metastasis suppressor 1
chr22_+_26443235 1.35 ENSDART00000044085
zgc:92480
zgc:92480
chr3_+_43955864 1.35 ENSDART00000168267
BX571715.1

chr24_-_26632171 1.35 ENSDART00000008374
ENSDART00000017384
tnikb
TRAF2 and NCK interacting kinase b
chr6_-_16717878 1.35 ENSDART00000153552
nomo
nodal modulator
chr8_-_16725959 1.34 ENSDART00000183593
depdc1a
DEP domain containing 1a
chr3_+_15893039 1.34 ENSDART00000055780
jpt2
Jupiter microtubule associated homolog 2
chr20_-_39596338 1.34 ENSDART00000023531
hey2
hes-related family bHLH transcription factor with YRPW motif 2
chr14_-_16082806 1.34 ENSDART00000165656
mxd3
MAX dimerization protein 3
chr16_+_44906324 1.34 ENSDART00000074960
cd22
cd22 molecule
chr1_+_496268 1.33 ENSDART00000109415
blzf1
basic leucine zipper nuclear factor 1
chr14_-_30905288 1.33 ENSDART00000173449
ENSDART00000173451
si:ch211-126c2.4
si:ch211-126c2.4
chr8_+_39619087 1.32 ENSDART00000134822
msi1
musashi RNA-binding protein 1
chr3_+_30190419 1.32 ENSDART00000157320
akt1s1
AKT1 substrate 1 (proline-rich)
chr13_-_21650404 1.30 ENSDART00000078352
tspan14
tetraspanin 14
chr9_-_18911608 1.30 ENSDART00000138785
si:dkey-239h2.3
si:dkey-239h2.3
chr10_+_23060391 1.29 ENSDART00000079711
slc25a1a
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1a
chr15_+_841383 1.28 ENSDART00000115077
zgc:174573
zgc:174573
chr3_-_47235997 1.27 ENSDART00000047071
tmed1a
transmembrane p24 trafficking protein 1a
chr3_-_5644028 1.26 ENSDART00000019957
ddx39ab
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Ab
chr15_-_33818872 1.26 ENSDART00000158325
n4bp2l2
NEDD4 binding protein 2-like 2
chr2_+_55365727 1.24 ENSDART00000162943
FP245456.1

chr15_+_8767650 1.23 ENSDART00000033871
ap2s1
adaptor-related protein complex 2, sigma 1 subunit
chr24_-_9300160 1.23 ENSDART00000152378
tgif1
TGFB-induced factor homeobox 1
chr17_+_28706946 1.23 ENSDART00000126967
strn3
striatin, calmodulin binding protein 3
chr5_-_26170225 1.23 ENSDART00000146363
ENSDART00000017696
fam151b
family with sequence similarity 151, member B
chr17_-_10000339 1.22 ENSDART00000162893
snx6
sorting nexin 6
chr1_+_38362412 1.21 ENSDART00000075086
cep44
centrosomal protein 44
chr7_-_41916505 1.20 ENSDART00000185785
dnaja2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr7_+_57795974 1.19 ENSDART00000148369
camk2d1
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1
chr18_-_18584839 1.17 ENSDART00000159274
sf3b3
splicing factor 3b, subunit 3
chr4_-_12477224 1.17 ENSDART00000027756
ENSDART00000182706
ENSDART00000127150
arhgef39
Rho guanine nucleotide exchange factor (GEF) 39
chr3_+_52899801 1.17 ENSDART00000058958
atp13a1
ATPase 13A1
chr14_-_33981544 1.16 ENSDART00000167774
foxa
forkhead box A sequence
chr6_+_33931740 1.15 ENSDART00000130492
ENSDART00000151213
orc1
origin recognition complex, subunit 1
chr4_+_5741733 1.15 ENSDART00000110243
pou3f2a
POU class 3 homeobox 2a
chr1_+_38142354 1.14 ENSDART00000179352
galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr25_+_20272145 1.13 ENSDART00000109605
si:dkey-219c3.2
si:dkey-219c3.2
chr6_+_1787160 1.13 ENSDART00000113505
myl9b
myosin, light chain 9b, regulatory
chr3_+_25087605 1.13 ENSDART00000138578
st13
ST13, Hsp70 interacting protein
chr15_+_25452092 1.12 ENSDART00000009545
pak4
p21 protein (Cdc42/Rac)-activated kinase 4
chr19_-_6840506 1.12 ENSDART00000081568
tcf19l
transcription factor 19 (SC1), like
chr14_+_31618982 1.12 ENSDART00000026195
slc9a6a
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6a
chr1_+_47178529 1.11 ENSDART00000158432
ENSDART00000074450
ENSDART00000137448
morc3b
MORC family CW-type zinc finger 3b
chr1_-_53277413 1.11 ENSDART00000150579
znf330
zinc finger protein 330
chr1_-_45215343 1.10 ENSDART00000014727
ddx39aa
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa
chr2_+_45300512 1.09 ENSDART00000144704
camsap2b
calmodulin regulated spectrin-associated protein family, member 2b
chr19_-_47474725 1.09 ENSDART00000165688
ncdn
neurochondrin
chr21_+_3796620 1.08 ENSDART00000099535
ENSDART00000144515
spout1
SPOUT domain containing methyltransferase 1
chr10_-_1788376 1.07 ENSDART00000123842
epb41l4a
erythrocyte membrane protein band 4.1 like 4A
chr8_+_49936585 1.07 ENSDART00000098707
naa35
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr25_-_19574146 1.06 ENSDART00000156811
si:ch211-59o9.10
si:ch211-59o9.10
chr22_+_33131891 1.06 ENSDART00000126885
dag1
dystroglycan 1
chr7_+_7511914 1.05 ENSDART00000172848
clcn3
chloride channel 3
chr3_+_42999844 1.05 ENSDART00000183950
ints1
integrator complex subunit 1
chr19_+_41520892 1.05 ENSDART00000182218
ENSDART00000115123
crtc2
CREB regulated transcription coactivator 2
chr17_-_12764360 1.04 ENSDART00000003418
brms1la
breast cancer metastasis-suppressor 1-like a
chr17_-_22573311 1.04 ENSDART00000141523
ENSDART00000140022
ENSDART00000079390
ENSDART00000188644
exo1
exonuclease 1
chr3_-_61375496 1.04 ENSDART00000165188
si:dkey-111k8.2
si:dkey-111k8.2
chr25_+_18583877 1.03 ENSDART00000148741
met
MET proto-oncogene, receptor tyrosine kinase
chr6_+_28018390 1.03 ENSDART00000123324
ENSDART00000150915
sap130a
Sin3A-associated protein a
chr18_-_18587745 1.02 ENSDART00000191973
sf3b3
splicing factor 3b, subunit 3
chr15_-_6615555 1.02 ENSDART00000152725
atm
ATM serine/threonine kinase
chr25_+_16043246 1.02 ENSDART00000186663
sb:cb470
sb:cb470
chr24_-_26981848 1.02 ENSDART00000183198
stag1b
stromal antigen 1b
chr4_-_75172216 1.01 ENSDART00000127522
naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr4_+_69823638 1.01 ENSDART00000165786
znf1087
zinc finger protein 1087
chr21_+_22423286 1.00 ENSDART00000133190
capslb
calcyphosine-like b
chr20_-_52882881 1.00 ENSDART00000111078
wu:fi04e12
wu:fi04e12
chr24_-_32665283 1.00 ENSDART00000038364
ca2
carbonic anhydrase II
chr13_-_44836727 0.99 ENSDART00000144385
si:dkeyp-2e4.3
si:dkeyp-2e4.3
chr8_+_24299321 0.98 ENSDART00000112046
ENSDART00000183558
ENSDART00000183796
ENSDART00000181395
ENSDART00000184555
ENSDART00000172531
ENSDART00000191663
ENSDART00000184103
ENSDART00000183676
ZNF335
si:ch211-269m15.3
chr10_+_32050906 0.98 ENSDART00000137373
si:ch211-266i6.3
si:ch211-266i6.3
chr17_-_45386546 0.98 ENSDART00000182647
tmem206
transmembrane protein 206
chr25_+_1591964 0.98 ENSDART00000093277
ppm1h
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr2_+_37837249 0.97 ENSDART00000113337
parp2
poly (ADP-ribose) polymerase 2
chr17_-_42568498 0.97 ENSDART00000014296
foxa2
forkhead box A2
chr6_-_55354004 0.97 ENSDART00000165911
pcif1
PDX1 C-terminal inhibiting factor 1
chr22_+_33135253 0.96 ENSDART00000004504
dag1
dystroglycan 1
chr16_-_26727032 0.96 ENSDART00000177668
rnf41l
ring finger protein 41, like
chr11_+_12811906 0.96 ENSDART00000123445
rtel1
regulator of telomere elongation helicase 1
chr7_+_7696665 0.96 ENSDART00000091099
ino80b
INO80 complex subunit B
chr19_+_40069524 0.95 ENSDART00000151365
ENSDART00000140926
zmym4
zinc finger, MYM-type 4
chr19_+_27342479 0.95 ENSDART00000184687
ddx39b
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr13_-_24263682 0.95 ENSDART00000176800
urb2
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr7_+_22981441 0.94 ENSDART00000182887
ccnb3
cyclin B3
chr11_-_36350421 0.94 ENSDART00000141477
psma5
proteasome subunit alpha 5
chr16_+_33121260 0.94 ENSDART00000058472
akirin1
akirin 1
chr13_-_18195942 0.94 ENSDART00000079902
slc25a16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr16_-_31718013 0.94 ENSDART00000190716
rbp5
retinol binding protein 1a, cellular
chr2_+_1989941 0.93 ENSDART00000190814
ssx2ipa
synovial sarcoma, X breakpoint 2 interacting protein a
chr22_-_36530902 0.93 ENSDART00000056188
polr2h
info polymerase (RNA) II (DNA directed) polypeptide H
chr7_-_12852406 0.92 ENSDART00000173127
sh3gl3a
SH3-domain GRB2-like 3a
chr3_-_25086986 0.92 ENSDART00000050245
xpnpep3
X-prolyl aminopeptidase 3, mitochondrial
chr15_-_20125331 0.92 ENSDART00000152355
med13b
mediator complex subunit 13b
chr2_+_19195841 0.92 ENSDART00000163137
ENSDART00000161095
elovl1a
ELOVL fatty acid elongase 1a
chr25_-_13789955 0.91 ENSDART00000167742
ENSDART00000165116
ENSDART00000171461
ckap5
cytoskeleton associated protein 5
chr12_-_34827477 0.91 ENSDART00000153026
NDUFAF8
si:dkey-21c1.6
chr6_-_58975010 0.89 ENSDART00000144911
ENSDART00000144514
mars
methionyl-tRNA synthetase
chr3_+_42999277 0.89 ENSDART00000163595
ints1
integrator complex subunit 1
chr2_+_38373272 0.89 ENSDART00000113111
psmb5
proteasome subunit beta 5
chr16_-_50952266 0.89 ENSDART00000165408
si:dkeyp-97a10.3
si:dkeyp-97a10.3
chr11_-_37720024 0.87 ENSDART00000023388
yod1
YOD1 deubiquitinase
chr20_+_9223514 0.87 ENSDART00000023293
kcnk5b
potassium channel, subfamily K, member 5b
chr24_-_16899406 0.86 ENSDART00000148753
mtrr
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr23_+_11285662 0.86 ENSDART00000111028
chl1a
cell adhesion molecule L1-like a
chr15_+_28175638 0.86 ENSDART00000037119
slc46a1
solute carrier family 46 (folate transporter), member 1
chr3_-_58733718 0.86 ENSDART00000154603
si:ch73-281f12.4
si:ch73-281f12.4
chr4_+_47636303 0.85 ENSDART00000167272
ENSDART00000166961
BX324142.1

chr20_-_29633507 0.85 ENSDART00000040292
cpsf3
cleavage and polyadenylation specific factor 3
chr10_+_16069987 0.84 ENSDART00000043936
megf10
multiple EGF-like-domains 10
chr22_-_10158038 0.84 ENSDART00000047444
rbck1
RanBP-type and C3HC4-type zinc finger containing 1
chr23_+_12455295 0.84 ENSDART00000143752
ENSDART00000135785
si:ch211-153a8.4
si:ch211-153a8.4
chr25_+_2776511 0.84 ENSDART00000115280
neo1b
neogenin 1b
chr24_-_4450238 0.83 ENSDART00000066835
fzd8a
frizzled class receptor 8a
chr7_+_10562118 0.83 ENSDART00000185188
ENSDART00000168801
zfand6
zinc finger, AN1-type domain 6
chr23_+_1702624 0.82 ENSDART00000149357
rabggta
Rab geranylgeranyltransferase, alpha subunit
chr2_-_9607879 0.82 ENSDART00000056899
txndc12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr1_-_57172294 0.82 ENSDART00000063774
rac1l
Rac family small GTPase 1, like
chr16_-_47301376 0.81 ENSDART00000169697
mios
missing oocyte, meiosis regulator, homolog (Drosophila)
chr12_+_19138452 0.81 ENSDART00000141346
ENSDART00000066397
phf5a
PHD finger protein 5A
chr15_+_11840311 0.81 ENSDART00000167671
prkd2
protein kinase D2
chr8_-_11770092 0.81 ENSDART00000091684
anapc7
anaphase promoting complex subunit 7
chr25_+_7532811 0.81 ENSDART00000161593
ptdss2
phosphatidylserine synthase 2
chr16_-_52728159 0.81 ENSDART00000158146
azin1a
antizyme inhibitor 1a
chr15_-_42283830 0.80 ENSDART00000015979
farsb
phenylalanyl-tRNA synthetase, beta subunit
chr18_-_34170918 0.80 ENSDART00000015079
slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr25_-_24233884 0.79 ENSDART00000146419
si:dkey-11e23.9
si:dkey-11e23.9
chr9_-_14504834 0.78 ENSDART00000056103
nrp2b
neuropilin 2b
chr18_+_7639401 0.78 ENSDART00000092416
rabl2
RAB, member of RAS oncogene family-like 2
chr13_+_46944607 0.77 ENSDART00000187352
fbxo5
F-box protein 5
chr12_+_38695808 0.77 ENSDART00000188726
ENSDART00000003339
dnai2b
dynein, axonemal, intermediate chain 2b

Network of associatons between targets according to the STRING database.

First level regulatory network of foxl1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.6 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
1.1 3.2 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.6 2.6 GO:0051661 maintenance of centrosome location(GO:0051661)
0.6 2.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.5 1.6 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.5 2.2 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.5 1.9 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.4 1.3 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.4 1.5 GO:0030224 monocyte differentiation(GO:0030224)
0.4 1.5 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.3 2.0 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.3 1.3 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.3 1.8 GO:0010269 response to selenium ion(GO:0010269)
0.3 0.8 GO:0060898 spinal cord radial glial cell differentiation(GO:0021531) eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.3 1.3 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) negative regulation of mesoderm development(GO:2000381)
0.3 0.8 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.3 1.5 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.3 2.0 GO:0033292 T-tubule organization(GO:0033292)
0.3 1.0 GO:0015670 carbon dioxide transport(GO:0015670)
0.2 0.9 GO:0071675 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675) positive regulation of lamellipodium organization(GO:1902745)
0.2 0.9 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 1.3 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.2 0.9 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.2 0.6 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.2 0.4 GO:0051645 Golgi localization(GO:0051645)
0.2 1.0 GO:0032289 central nervous system myelin formation(GO:0032289)
0.2 0.8 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.2 0.8 GO:0018343 protein farnesylation(GO:0018343)
0.2 2.1 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.2 0.8 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.2 0.5 GO:0034773 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773) regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.2 0.8 GO:0018344 protein geranylgeranylation(GO:0018344)
0.2 0.8 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.2 1.2 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.2 1.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 0.5 GO:2000009 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.1 1.0 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 0.4 GO:0090435 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.1 0.7 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 0.6 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 1.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.7 GO:0007412 axon target recognition(GO:0007412)
0.1 4.8 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 0.7 GO:0060585 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 1.9 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 0.8 GO:0089700 endocardial cushion formation(GO:0003272) protein kinase D signaling(GO:0089700)
0.1 0.8 GO:0015846 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.4 GO:0070126 mitochondrial translational termination(GO:0070126)
0.1 0.5 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.5 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.6 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.6 GO:0052651 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.7 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.8 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.4 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.5 GO:0099625 regulation of membrane repolarization(GO:0060306) regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.1 0.7 GO:1902751 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1 1.9 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 1.1 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.6 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.1 1.0 GO:0032205 negative regulation of telomere maintenance(GO:0032205)
0.1 0.5 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.1 0.6 GO:1904396 regulation of neuromuscular junction development(GO:1904396)
0.1 0.6 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.4 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 3.9 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 0.7 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.6 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 1.7 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.5 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.1 1.1 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 0.6 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.5 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 0.5 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 1.0 GO:0001881 receptor recycling(GO:0001881)
0.1 1.3 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 2.0 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.1 0.8 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.3 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.3 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.1 0.7 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.1 0.6 GO:0048796 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.1 0.7 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.1 0.8 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.1 0.7 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.1 1.9 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.7 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.3 GO:0010039 response to iron ion(GO:0010039)
0.1 0.8 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 0.9 GO:0050667 homocysteine metabolic process(GO:0050667)
0.1 0.6 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.1 1.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.1 1.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.9 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 1.7 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 2.1 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1 0.5 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.5 GO:0031268 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 1.0 GO:0033505 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.1 0.5 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.6 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.3 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.4 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 1.1 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.9 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0003352 regulation of cilium movement(GO:0003352)
0.0 0.3 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.3 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 1.9 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.6 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.7 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.6 GO:0045116 protein neddylation(GO:0045116)
0.0 0.8 GO:0072662 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 1.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.6 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 2.8 GO:0051225 spindle assembly(GO:0051225)
0.0 0.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.9 GO:0006298 mismatch repair(GO:0006298)
0.0 1.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.7 GO:0010043 response to zinc ion(GO:0010043)
0.0 0.8 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.2 GO:0071543 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.5 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.1 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.7 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.8 GO:0021955 central nervous system neuron axonogenesis(GO:0021955)
0.0 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 1.0 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 1.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.4 GO:0016203 muscle attachment(GO:0016203)
0.0 0.6 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 0.3 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 3.9 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.7 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 2.0 GO:0006400 tRNA modification(GO:0006400)
0.0 5.7 GO:0032259 methylation(GO:0032259)
0.0 0.1 GO:0043383 chemokine production(GO:0032602) negative T cell selection(GO:0043383) thymocyte migration(GO:0072679)
0.0 0.5 GO:0035476 angioblast cell migration(GO:0035476)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 1.4 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.0 0.6 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.2 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284) regulation of erythrocyte differentiation(GO:0045646)
0.0 0.4 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 1.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 1.0 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.6 GO:0006284 base-excision repair(GO:0006284)
0.0 0.7 GO:0030901 midbrain development(GO:0030901)
0.0 0.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:0007032 endosome organization(GO:0007032)
0.0 0.2 GO:0070293 renal absorption(GO:0070293)
0.0 0.6 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.2 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 1.8 GO:0051321 meiotic cell cycle(GO:0051321)
0.0 1.3 GO:0007030 Golgi organization(GO:0007030)
0.0 0.8 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.3 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.2 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.9 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.8 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.2 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.3 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 1.7 GO:0001889 liver development(GO:0001889)
0.0 1.7 GO:0060026 convergent extension(GO:0060026)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0070545 PeBoW complex(GO:0070545)
0.4 4.8 GO:0031010 ISWI-type complex(GO:0031010)
0.4 1.9 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.4 1.5 GO:0097268 cytoophidium(GO:0097268)
0.4 1.1 GO:0031417 NatC complex(GO:0031417)
0.3 2.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 2.2 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.2 0.7 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.2 2.0 GO:0016011 dystroglycan complex(GO:0016011)
0.2 2.6 GO:0016580 Sin3 complex(GO:0016580)
0.2 0.8 GO:0005880 nuclear microtubule(GO:0005880)
0.2 2.1 GO:0070822 Sin3-type complex(GO:0070822)
0.2 0.8 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 0.8 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.2 1.5 GO:0070652 HAUS complex(GO:0070652)
0.2 1.2 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.1 0.4 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 1.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 3.5 GO:0030686 90S preribosome(GO:0030686)
0.1 0.6 GO:0018444 translation release factor complex(GO:0018444)
0.1 1.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 1.1 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.8 GO:0071797 LUBAC complex(GO:0071797)
0.1 1.9 GO:0032039 integrator complex(GO:0032039)
0.1 0.5 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 1.6 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.9 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.4 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.1 0.3 GO:0097519 DNA recombinase complex(GO:0097519)
0.1 1.0 GO:0014704 intercalated disc(GO:0014704)
0.1 0.6 GO:0032797 SMN complex(GO:0032797)
0.1 0.5 GO:0035060 brahma complex(GO:0035060)
0.1 1.0 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 2.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.1 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.9 GO:0005839 proteasome core complex(GO:0005839)
0.0 1.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.9 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.6 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.6 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 1.0 GO:0008278 cohesin complex(GO:0008278)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 2.9 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.7 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 1.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 1.2 GO:0030496 midbody(GO:0030496)
0.0 2.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 7.7 GO:0005730 nucleolus(GO:0005730)
0.0 3.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0043514 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.4 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.7 GO:0005814 centriole(GO:0005814)
0.0 0.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.6 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.6 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.9 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.5 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.0 0.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.5 GO:0005902 microvillus(GO:0005902)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.4 2.2 GO:0030620 U2 snRNA binding(GO:0030620)
0.4 2.7 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.4 1.5 GO:0003883 CTP synthase activity(GO:0003883)
0.3 2.0 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.3 2.6 GO:0035198 miRNA binding(GO:0035198)
0.3 1.0 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.2 0.7 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.2 3.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.7 GO:0003994 aconitate hydratase activity(GO:0003994)
0.2 1.0 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.2 1.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 0.7 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.2 2.5 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.2 0.9 GO:0030586 [methionine synthase] reductase activity(GO:0030586)
0.2 0.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 0.8 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.2 0.8 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.2 1.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 0.6 GO:0042806 fucose binding(GO:0042806)
0.2 0.8 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 2.7 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.2 0.8 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.2 0.6 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2 0.5 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.2 0.9 GO:0005542 folic acid binding(GO:0005542)
0.2 0.5 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.2 0.6 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.1 2.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 1.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 2.8 GO:0008301 DNA binding, bending(GO:0008301)
0.1 3.0 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.7 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 1.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.8 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.5 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.1 0.8 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 0.7 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.6 GO:0009374 biotin binding(GO:0009374)
0.1 0.4 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.5 GO:0043142 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 1.7 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.1 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.1 0.9 GO:0016918 retinal binding(GO:0016918)
0.1 0.4 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.1 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.8 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 1.0 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 0.5 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.9 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 1.1 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1 0.4 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.1 1.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.5 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.4 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.9 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.6 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.8 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 1.4 GO:0051020 GTPase binding(GO:0051020)
0.0 0.4 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 3.3 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.4 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.4 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 1.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.8 GO:0043236 laminin binding(GO:0043236)
0.0 1.6 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 16.8 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.4 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.4 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 2.3 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.3 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.8 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0042164 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.0 0.3 GO:0003916 DNA topoisomerase activity(GO:0003916) DNA topoisomerase type I activity(GO:0003917)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.5 GO:0016411 acylglycerol O-acyltransferase activity(GO:0016411)
0.0 1.7 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.9 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.7 GO:0019956 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 0.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.8 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.7 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.6 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 2.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.5 GO:0031491 nucleosome binding(GO:0031491)
0.0 3.5 GO:0000989 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.2 2.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 4.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 5.9 PID FGF PATHWAY FGF signaling pathway
0.1 3.2 PID PLK1 PATHWAY PLK1 signaling events
0.1 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.4 PID LKB1 PATHWAY LKB1 signaling events
0.1 1.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 0.9 PID AURORA A PATHWAY Aurora A signaling
0.1 1.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.3 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 2.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.2 PID E2F PATHWAY E2F transcription factor network
0.0 0.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID AURORA B PATHWAY Aurora B signaling
0.0 0.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.2 1.9 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 0.8 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1 1.4 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 1.8 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.1 2.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 1.0 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 3.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 4.7 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 1.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 0.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 1.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 0.5 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 2.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 1.1 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 1.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 0.6 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 1.1 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 1.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.8 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.8 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.1 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.5 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.8 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER