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PRJEB1986: zebrafish developmental stages transcriptome

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Results for gli1+gli2b

Z-value: 0.95

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Transcription factors associated with gli1+gli2b

Gene Symbol Gene ID Gene Info
gli2b
ENSDARG00000020884 GLI family zinc finger 2b
gli1
ENSDARG00000101244 GLI family zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gli1dr11_v1_chr6_-_59505589_59505589-0.615.4e-03Click!
gli2bdr11_v1_chr11_+_43661735_43661735-0.615.8e-03Click!

Activity profile of gli1+gli2b motif

Sorted Z-values of gli1+gli2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_464007 3.58 ENSDART00000106669
dhrs7cb
dehydrogenase/reductase (SDR family) member 7Cb
chr20_+_35484070 3.21 ENSDART00000026234
ENSDART00000141675
mep1a.2
meprin A, alpha (PABA peptide hydrolase), tandem duplicate 2
chr12_-_4756478 3.09 ENSDART00000152181
mapta
microtubule-associated protein tau a
chr4_-_8040436 2.72 ENSDART00000113033
si:ch211-240l19.6
si:ch211-240l19.6
chr9_-_46399611 2.57 ENSDART00000164914
ENSDART00000145931
lct
si:dkey-79p17.3
lactase
si:dkey-79p17.3
chr24_-_6158933 2.49 ENSDART00000021609
gad2
glutamate decarboxylase 2
chr20_-_25518488 2.38 ENSDART00000186993
cyp2n13
cytochrome P450, family 2, subfamily N, polypeptide 13
chr14_+_15155684 2.37 ENSDART00000167966
zgc:158852
zgc:158852
chr21_-_41873065 2.31 ENSDART00000014538
endou2
endonuclease, polyU-specific 2
chr6_+_42918933 2.31 ENSDART00000064896
gnat1
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
chr1_-_21599219 2.21 ENSDART00000148327
adamtsl7
ADAMTS-like 7
chr17_-_17447899 2.21 ENSDART00000156928
ENSDART00000109034
nrxn3a
neurexin 3a
chr2_+_51783120 2.14 ENSDART00000177559
crygn1
crystallin, gamma N1
chr11_+_44300548 1.94 ENSDART00000191626
CABZ01100304.1

chr20_+_13969414 1.92 ENSDART00000049864
rd3
retinal degeneration 3
chr21_+_10739846 1.92 ENSDART00000084011
cplx4a
complexin 4a
chr13_+_3954540 1.91 ENSDART00000092646
lrrc73
leucine rich repeat containing 73
chr17_+_30587333 1.87 ENSDART00000156500
nhsl1a
NHS-like 1a
chr19_-_10243148 1.82 ENSDART00000148073
shisa7b
shisa family member 7
chr19_-_6988837 1.79 ENSDART00000145741
ENSDART00000167640
znf384l
zinc finger protein 384 like
chr12_-_31422433 1.75 ENSDART00000186075
ENSDART00000153172
ENSDART00000066256
vti1a
vesicle transport through interaction with t-SNAREs 1A
chr23_+_20422661 1.74 ENSDART00000144047
ENSDART00000104336
tnnc2
troponin C type 2 (fast)
chr2_+_54482603 1.73 ENSDART00000130977
ENSDART00000183090
mtcl1
microtubule crosslinking factor 1
chr2_+_46589798 1.73 ENSDART00000128457
ENSDART00000145347
ephb1
EPH receptor B1
chr24_+_3972260 1.65 ENSDART00000131753
pfkpa
phosphofructokinase, platelet a
chr4_-_17741513 1.61 ENSDART00000141680
mybpc1
myosin binding protein C, slow type
chr2_-_57707039 1.58 ENSDART00000097685
CABZ01060891.1

chr18_+_25653599 1.54 ENSDART00000007856
fkbp16
FK506 binding protein 16
chr5_-_2752573 1.46 ENSDART00000168121
lzts3a
leucine zipper, putative tumor suppressor family member 3a
chr21_-_41873584 1.45 ENSDART00000188089
endou2
endonuclease, polyU-specific 2
chr19_+_49721 1.44 ENSDART00000160489
col14a1b
collagen, type XIV, alpha 1b
chr23_+_28582865 1.42 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr14_+_15231097 1.41 ENSDART00000172430
si:dkey-203a12.3
si:dkey-203a12.3
chr6_-_11768198 1.41 ENSDART00000183463
march7
membrane-associated ring finger (C3HC4) 7
chr20_-_915234 1.38 ENSDART00000164816
cnr1
cannabinoid receptor 1
chr2_-_30784502 1.36 ENSDART00000056735
rgs20
regulator of G protein signaling 20
chr15_+_7992906 1.34 ENSDART00000090790
cadm2b
cell adhesion molecule 2b
chr7_+_29952169 1.32 ENSDART00000173540
ENSDART00000173940
ENSDART00000173906
ENSDART00000173772
ENSDART00000173506
ENSDART00000039657
tpma
alpha-tropomyosin
chr12_+_47162456 1.32 ENSDART00000186272
ENSDART00000180811
RYR2
ryanodine receptor 2
chr19_+_56351 1.29 ENSDART00000168334
col14a1b
collagen, type XIV, alpha 1b
chr17_-_722218 1.28 ENSDART00000160385
SLC25A29
solute carrier family 25 member 29
chr10_-_35542071 1.28 ENSDART00000162139
si:ch211-244c8.4
si:ch211-244c8.4
chr3_+_19621034 1.25 ENSDART00000025358
itgb3a
integrin beta 3a
chr6_-_30859656 1.23 ENSDART00000156235
pde4ba
phosphodiesterase 4B, cAMP-specific a
chr14_-_45702721 1.21 ENSDART00000165727
si:dkey-226n24.1
si:dkey-226n24.1
chr1_-_31505144 1.17 ENSDART00000087115
rims1b
regulating synaptic membrane exocytosis 1b
chr24_-_38574631 1.16 ENSDART00000154539
slc17a7b
solute carrier family 17 (vesicular glutamate transporter), member 7b
chr17_-_50331351 1.15 ENSDART00000149294
otofb
otoferlin b
chr2_-_30784198 1.13 ENSDART00000182523
ENSDART00000147355
rgs20
regulator of G protein signaling 20
chr24_-_21587335 1.12 ENSDART00000091528
gpr12
G protein-coupled receptor 12
chr17_-_26604946 1.12 ENSDART00000087062
fam149b1
family with sequence similarity 149, member B1
chr7_+_10701938 1.10 ENSDART00000158162
arnt2
aryl-hydrocarbon receptor nuclear translocator 2
chr5_-_34185115 1.09 ENSDART00000192771
fibcd1
fibrinogen C domain containing 1
chr1_+_59090743 1.09 ENSDART00000100199
mfap4
microfibril associated protein 4
chr5_+_13472234 1.07 ENSDART00000114069
ENSDART00000132406
cnnm4b
cyclin and CBS domain divalent metal cation transport mediator 4b
chr22_-_38459316 1.06 ENSDART00000149683
ENSDART00000098461
ptk7a
protein tyrosine kinase 7a
chr20_+_27194833 1.06 ENSDART00000150072
si:dkey-85n7.8
si:dkey-85n7.8
chr24_+_39137001 1.04 ENSDART00000181086
ENSDART00000183724
ENSDART00000193466
tbc1d24
TBC1 domain family, member 24
chr19_+_9050852 1.04 ENSDART00000151031
ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr9_+_45227028 1.04 ENSDART00000185579
adarb1b
adenosine deaminase, RNA-specific, B1b
chr5_-_17876709 1.02 ENSDART00000141978
si:dkey-112e17.1
si:dkey-112e17.1
chr7_+_29951997 1.01 ENSDART00000173453
tpma
alpha-tropomyosin
chr13_+_228045 0.99 ENSDART00000161091
zgc:64201
zgc:64201
chr5_-_34185497 0.98 ENSDART00000146321
fibcd1
fibrinogen C domain containing 1
chr5_-_25123807 0.97 ENSDART00000183171
abca2
ATP-binding cassette, sub-family A (ABC1), member 2
chr8_-_18316482 0.96 ENSDART00000190156
rnf220b
ring finger protein 220b
chr23_+_26009266 0.95 ENSDART00000054025
si:dkey-78k11.9
si:dkey-78k11.9
chr25_-_28384954 0.94 ENSDART00000073500
ptprz1a
protein tyrosine phosphatase, receptor-type, Z polypeptide 1a
chr7_+_4162994 0.94 ENSDART00000172800
si:ch211-63p21.1
si:ch211-63p21.1
chr7_+_53156810 0.90 ENSDART00000189816
cdh29
cadherin 29
chr9_-_33749556 0.89 ENSDART00000149383
ndp
Norrie disease (pseudoglioma)
chr9_-_46072805 0.89 ENSDART00000169682
hdac4
histone deacetylase 4
chr13_-_865193 0.89 ENSDART00000187053
AL929536.7

chr16_-_31644545 0.86 ENSDART00000181634
CR855311.5

chr10_+_5645887 0.82 ENSDART00000171426
pdzph1
PDZ and pleckstrin homology domains 1
chr14_+_15597049 0.80 ENSDART00000159732
si:dkey-203a12.8
si:dkey-203a12.8
chr2_+_30147504 0.80 ENSDART00000190947
kcnb2
potassium voltage-gated channel, Shab-related subfamily, member 2
chr7_+_29952719 0.78 ENSDART00000173737
tpma
alpha-tropomyosin
chr15_+_16525126 0.77 ENSDART00000193455
galnt17
polypeptide N-acetylgalactosaminyltransferase 17
chr13_-_50002852 0.76 ENSDART00000099439
lyst
lysosomal trafficking regulator
chr10_-_45379831 0.76 ENSDART00000186205
CABZ01117348.1

chr3_-_16068236 0.74 ENSDART00000157315
si:dkey-81l17.6
si:dkey-81l17.6
chr9_+_4252839 0.74 ENSDART00000169740
kalrna
kalirin RhoGEF kinase a
chr14_-_33821515 0.73 ENSDART00000173218
vimr2
vimentin-related 2
chr4_+_5132951 0.72 ENSDART00000103279
ccnd2b
cyclin D2, b
chr17_-_7371564 0.71 ENSDART00000060336
rab32b
RAB32b, member RAS oncogene family
chr1_+_59090583 0.71 ENSDART00000150658
mfap4
microfibril associated protein 4
chr5_+_69878693 0.71 ENSDART00000073671
ythdc1
YTH domain containing 1
chr13_-_9598320 0.70 ENSDART00000184613
cpxm1a
carboxypeptidase X (M14 family), member 1a
chr4_-_5856200 0.69 ENSDART00000121936
slc5a8
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
chr19_-_42651615 0.68 ENSDART00000123360
susd5
sushi domain containing 5
chr16_-_12784373 0.68 ENSDART00000080396
foxj2
forkhead box J2
chr25_+_26923193 0.68 ENSDART00000187364
grm8b
glutamate receptor, metabotropic 8b
chr14_+_15331486 0.68 ENSDART00000172077
ENSDART00000183370
ENSDART00000182467
SPINK2
si:dkey-203a12.5
si:dkey-203a12.4
si:dkey-203a12.5
chr8_-_14121634 0.67 ENSDART00000184946
bgna
biglycan a
chr6_-_31326398 0.66 ENSDART00000190749
ENSDART00000192789
dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr8_+_1065458 0.64 ENSDART00000081432
sprb
sepiapterin reductase b
chr25_+_7461624 0.63 ENSDART00000170569
syt12
synaptotagmin XII
chr10_-_15053507 0.61 ENSDART00000157446
ENSDART00000170441
CLDN23
si:ch211-95j8.5
chr10_-_39154594 0.61 ENSDART00000148825
slc37a4b
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr25_+_30298377 0.60 ENSDART00000153622
C11orf96
chromosome 11 open reading frame 96
chr23_+_4226341 0.60 ENSDART00000012445
zgc:113278
zgc:113278
chr18_-_1143996 0.60 ENSDART00000189186
ENSDART00000136140
hcn4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr15_+_42431198 0.59 ENSDART00000189951
ENSDART00000089694
tiam1b
T cell lymphoma invasion and metastasis 1b
chr11_+_2855430 0.55 ENSDART00000172837
kif21b
kinesin family member 21B
chr4_-_2219705 0.54 ENSDART00000131046
si:ch73-278m9.1
si:ch73-278m9.1
chr1_+_19434198 0.53 ENSDART00000012552
clockb
clock circadian regulator b
chr6_+_7123980 0.52 ENSDART00000179738
ENSDART00000151311
si:ch211-237c6.4
si:ch211-237c6.4
chr10_+_42691210 0.52 ENSDART00000193813
rhobtb2b
Rho-related BTB domain containing 2b
chr18_-_16395668 0.51 ENSDART00000186004
mgat4c
mgat4 family, member C
chr10_-_44411032 0.50 ENSDART00000111509
CABZ01072096.1

chr10_-_15910974 0.50 ENSDART00000148169
pip5k1ba
phosphatidylinositol-4-phosphate 5-kinase, type I, beta a
chr6_+_11850359 0.47 ENSDART00000109552
ENSDART00000188139
ENSDART00000181499
ENSDART00000178269
baz2ba
bromodomain adjacent to zinc finger domain, 2Ba
chr21_-_8370500 0.47 ENSDART00000055328
nek6
NIMA-related kinase 6
chr4_+_27130412 0.44 ENSDART00000145083
brd1a
bromodomain containing 1a
chr25_-_3087556 0.42 ENSDART00000193249
best1
bestrophin 1
chr2_+_54086436 0.42 ENSDART00000174581
CU179656.1

chr12_+_30367079 0.42 ENSDART00000190112
ccdc186
si:ch211-225b10.4
chr1_+_31706668 0.42 ENSDART00000057879
as3mt
arsenite methyltransferase
chr14_+_25464681 0.42 ENSDART00000067500
ENSDART00000187601
si:dkey-280e21.3
si:dkey-280e21.3
chr23_-_33038423 0.41 ENSDART00000180539
plxna2
plexin A2
chr24_-_39518599 0.41 ENSDART00000145606
ENSDART00000031486
lyrm1
LYR motif containing 1
chr18_-_17485419 0.40 ENSDART00000018764
foxl1
forkhead box L1
chr19_-_26235219 0.39 ENSDART00000104008
dtnbp1b
dystrobrevin binding protein 1b
chr5_+_36439405 0.39 ENSDART00000102973
eda
ectodysplasin A
chr9_+_56194410 0.39 ENSDART00000168530
LO018176.1

chr8_-_7078575 0.37 ENSDART00000137413
si:ch73-233m11.2
si:ch73-233m11.2
chr11_+_40831620 0.35 ENSDART00000160023
errfi1a
ERBB receptor feedback inhibitor 1a
chr21_-_36948 0.34 ENSDART00000181230
JMY
junction mediating and regulatory protein, p53 cofactor
chr3_-_25814097 0.33 ENSDART00000169706
ntn1b
netrin 1b
chr14_+_15257658 0.33 ENSDART00000161625
ENSDART00000193577
si:dkey-77g12.4
si:dkey-203a12.5
si:dkey-77g12.4
si:dkey-203a12.5
chr22_+_26665422 0.32 ENSDART00000164994
adcy9
adenylate cyclase 9
chr12_-_30338779 0.32 ENSDART00000192511
vwa2
von Willebrand factor A domain containing 2
chr22_-_3261879 0.32 ENSDART00000159643
gpr35.1
G protein-coupled receptor 35, tandem duplicate 1
chr23_+_44049509 0.32 ENSDART00000102003
txk
TXK tyrosine kinase
chr23_+_18779043 0.32 ENSDART00000158267
emp3b
epithelial membrane protein 3b
chr15_-_19128705 0.31 ENSDART00000152428
arhgap32a
Rho GTPase activating protein 32a
chr3_+_48561112 0.31 ENSDART00000159682
slc16a5b
solute carrier family 16 (monocarboxylate transporter), member 5b
chr18_+_5547185 0.30 ENSDART00000193977
nnt2
nicotinamide nucleotide transhydrogenase 2
chr1_+_55293424 0.30 ENSDART00000152464
zgc:172106
zgc:172106
chr7_+_18075504 0.26 ENSDART00000173689
si:ch73-40a2.1
si:ch73-40a2.1
chr20_+_26095530 0.25 ENSDART00000139350
syne1a
spectrin repeat containing, nuclear envelope 1a
chr16_-_40373836 0.25 ENSDART00000134498
si:dkey-242e21.3
si:dkey-242e21.3
chr16_+_13822137 0.24 ENSDART00000163251
flcn
folliculin
chr17_-_8562586 0.23 ENSDART00000154257
ENSDART00000157308
fzd3b
frizzled class receptor 3b
chr12_+_30367371 0.23 ENSDART00000153364
ccdc186
si:ch211-225b10.4
chr11_-_21304452 0.23 ENSDART00000163008
RASSF5
si:dkey-85p17.3
chr23_+_42304602 0.23 ENSDART00000166004
cyp2aa11
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr7_+_31871830 0.22 ENSDART00000139899
mybpc3
myosin binding protein C, cardiac
chr8_+_28469054 0.22 ENSDART00000062716
slc52a3
solute carrier family 52 (riboflavin transporter), member 3
chr20_-_54377933 0.19 ENSDART00000182664
entpd5b
ectonucleoside triphosphate diphosphohydrolase 5b
chr24_+_39518774 0.17 ENSDART00000132939
dcun1d3
defective in cullin neddylation 1 domain containing 3
chr19_+_13994563 0.17 ENSDART00000164696
tmem222b
transmembrane protein 222b
chr11_+_24314148 0.16 ENSDART00000171491
rem1
RAS (RAD and GEM)-like GTP-binding 1
chr13_-_40754499 0.16 ENSDART00000111641
ENSDART00000159255
morn4
MORN repeat containing 4
chr22_+_38762693 0.15 ENSDART00000015016
ENSDART00000150187
alpi.1
alkaline phosphatase, intestinal, tandem duplicate 1
chr12_+_18358082 0.14 ENSDART00000123315
si:dkey-7e14.3
si:dkey-7e14.3
chr14_-_15171435 0.14 ENSDART00000159148
ENSDART00000166622
si:dkey-77g12.1
si:dkey-77g12.1
chr16_-_37964325 0.14 ENSDART00000148801
mrap2a
melanocortin 2 receptor accessory protein 2a
chr25_+_32473433 0.14 ENSDART00000152326
sqor
sulfide quinone oxidoreductase
chr2_-_12242695 0.13 ENSDART00000158175
gpr158b
G protein-coupled receptor 158b
chr8_-_43847138 0.13 ENSDART00000148358
adgrd1
adhesion G protein-coupled receptor D1
chr21_+_45819662 0.11 ENSDART00000193362
ENSDART00000184255
pitx1
paired-like homeodomain 1
chr5_-_18043460 0.11 ENSDART00000082583
rnf215
ring finger protein 215
chr5_+_10046643 0.10 ENSDART00000137543
ENSDART00000186917
gstt2
glutathione S-transferase theta 2
chr25_-_12982193 0.09 ENSDART00000159617
ccl39.5
chemokine (C-C motif) ligand 39, duplicate 5
chr21_+_13389499 0.07 ENSDART00000151268
zgc:113162
zgc:113162
chr20_+_2669017 0.06 ENSDART00000058777
slc35a1
solute carrier family 35 (CMP-sialic acid transporter), member A1
chr5_-_25620594 0.04 ENSDART00000189346
cyp1d1
cytochrome P450, family 1, subfamily D, polypeptide 1
chr14_+_15430991 0.04 ENSDART00000158221
si:dkey-203a12.5
si:dkey-203a12.5
chr16_+_12632428 0.03 ENSDART00000184600
ENSDART00000180537
nat14
N-acetyltransferase 14 (GCN5-related, putative)
chr6_-_436658 0.02 ENSDART00000191515
grap2b
GRB2-related adaptor protein 2b
chr2_-_44199722 0.02 ENSDART00000140633
ENSDART00000145728
sdhc
succinate dehydrogenase complex, subunit C, integral membrane protein
chr10_+_40235959 0.00 ENSDART00000145862
gramd1ba
GRAM domain containing 1Ba

Network of associatons between targets according to the STRING database.

First level regulatory network of gli1+gli2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 0.9 GO:0090299 regulation of neural crest formation(GO:0090299)
0.2 2.3 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.2 1.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 1.7 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 1.4 GO:0038171 cannabinoid signaling pathway(GO:0038171) positive regulation of feeding behavior(GO:2000253)
0.2 1.7 GO:0006735 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 1.2 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 0.4 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.1 0.4 GO:0003403 optic vesicle formation(GO:0003403)
0.1 1.1 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 1.1 GO:0090660 cerebrospinal fluid circulation(GO:0090660) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.7 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.9 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 1.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.3 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.1 0.4 GO:0060155 secretory granule organization(GO:0033363) platelet dense granule organization(GO:0060155)
0.1 1.5 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 1.1 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 1.7 GO:0014823 response to activity(GO:0014823)
0.1 1.0 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 1.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 1.2 GO:0070527 platelet aggregation(GO:0070527)
0.1 1.0 GO:0048796 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.1 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.1 3.4 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 0.6 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 1.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.7 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 0.6 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 2.6 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.3 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.7 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.2 GO:0003210 cardiac atrium formation(GO:0003210)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.2 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.7 GO:0032438 melanosome organization(GO:0032438)
0.0 1.9 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.0 0.2 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.4 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 2.5 GO:0061515 myeloid cell development(GO:0061515)
0.0 0.6 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.7 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.8 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.9 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.7 GO:0015908 fatty acid transport(GO:0015908)
0.0 1.6 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 0.5 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.5 GO:0009648 photoperiodism(GO:0009648)
0.0 1.0 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 1.7 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.6 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 1.7 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.4 GO:0042476 odontogenesis(GO:0042476)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 1.1 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.0 GO:0016586 RSC complex(GO:0016586)
0.1 1.4 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.5 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 1.2 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.9 GO:0043195 terminal bouton(GO:0043195)
0.1 1.0 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.0 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 1.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.3 GO:0001650 fibrillar center(GO:0001650)
0.0 1.7 GO:0005861 troponin complex(GO:0005861)
0.0 1.2 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.0 2.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.2 GO:0008305 integrin complex(GO:0008305)
0.0 3.1 GO:0005884 actin filament(GO:0005884)
0.0 0.4 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.9 GO:0016342 catenin complex(GO:0016342)
0.0 2.1 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.4 1.2 GO:0070051 fibrinogen binding(GO:0070051)
0.3 1.4 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.3 1.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 2.6 GO:0008422 beta-glucosidase activity(GO:0008422)
0.2 0.5 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 1.7 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.4 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.1 0.7 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 1.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.0 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 0.7 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 1.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 1.2 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.1 0.5 GO:0070888 E-box binding(GO:0070888)
0.1 0.3 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 2.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.9 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 3.8 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 1.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.8 GO:0003823 antigen binding(GO:0003823)
0.1 1.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 2.5 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 1.0 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 5.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0031781 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.6 GO:0030552 cAMP binding(GO:0030552)
0.0 0.4 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 2.5 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.6 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.4 GO:0048018 death receptor binding(GO:0005123) receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 2.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.3 GO:0008013 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) beta-catenin binding(GO:0008013)
0.0 1.2 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.7 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.0 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.5 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 2.7 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 1.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 0.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 2.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 2.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 3.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 2.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 1.0 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.7 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.7 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.9 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events