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PRJEB1986: zebrafish developmental stages transcriptome

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Results for gli2a+gli3

Z-value: 0.76

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Transcription factors associated with gli2a+gli3

Gene Symbol Gene ID Gene Info
gli2a
ENSDARG00000025641 GLI family zinc finger 2a
gli3
ENSDARG00000052131 GLI family zinc finger 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gli2adr11_v1_chr9_+_37141836_37141836-0.871.7e-06Click!
gli3dr11_v1_chr24_-_11821505_11821505-0.804.1e-05Click!

Activity profile of gli2a+gli3 motif

Sorted Z-values of gli2a+gli3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_3252950 5.60 ENSDART00000020671
prph2b
peripherin 2b (retinal degeneration, slow)
chr16_+_52512025 4.00 ENSDART00000056095
fabp10a
fatty acid binding protein 10a, liver basic
chr10_-_22854758 3.16 ENSDART00000079449
and3
actinodin3
chr5_+_51594209 2.24 ENSDART00000164668
ENSDART00000058403
ENSDART00000055857
ckmt2b
creatine kinase, mitochondrial 2b (sarcomeric)
chr6_-_35446110 2.23 ENSDART00000058773
rgs16
regulator of G protein signaling 16
chr13_+_3954540 2.01 ENSDART00000092646
lrrc73
leucine rich repeat containing 73
chr21_+_10739846 1.95 ENSDART00000084011
cplx4a
complexin 4a
chr19_-_40192249 1.95 ENSDART00000051972
grn1
granulin 1
chr2_+_51783120 1.94 ENSDART00000177559
crygn1
crystallin, gamma N1
chr23_-_27875140 1.85 ENSDART00000143662
ankrd33aa
ankyrin repeat domain 33Aa
chr17_-_51202339 1.75 ENSDART00000167117
si:ch1073-469d17.2
si:ch1073-469d17.2
chr23_+_28582865 1.64 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr2_-_30784502 1.56 ENSDART00000056735
rgs20
regulator of G protein signaling 20
chr25_-_210730 1.56 ENSDART00000187580
FP236318.1

chr12_-_464007 1.55 ENSDART00000106669
dhrs7cb
dehydrogenase/reductase (SDR family) member 7Cb
chr15_+_7992906 1.53 ENSDART00000090790
cadm2b
cell adhesion molecule 2b
chr2_-_57707039 1.52 ENSDART00000097685
CABZ01060891.1

chr4_+_72797711 1.47 ENSDART00000190934
ENSDART00000163236
MYRFL
myelin regulatory factor-like
chr19_-_10243148 1.47 ENSDART00000148073
shisa7b
shisa family member 7
chr4_-_55785014 1.46 ENSDART00000181348
CT583728.24

chr4_-_55801210 1.46 ENSDART00000186943
CT583728.13

chr4_-_55829342 1.46 ENSDART00000185611
CT583728.26

chr20_+_27194833 1.44 ENSDART00000150072
si:dkey-85n7.8
si:dkey-85n7.8
chr4_-_17741513 1.43 ENSDART00000141680
mybpc1
myosin binding protein C, slow type
chr25_-_17403598 1.43 ENSDART00000104216
cyp2x9
cytochrome P450, family 2, subfamily X, polypeptide 9
chr16_+_20220225 1.32 ENSDART00000182208
colq
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr23_+_20422661 1.28 ENSDART00000144047
ENSDART00000104336
tnnc2
troponin C type 2 (fast)
chr6_-_10320676 1.26 ENSDART00000151247
scn1lab
sodium channel, voltage-gated, type I like, alpha b
chr23_+_43834376 1.25 ENSDART00000148989
si:ch211-149b19.4
si:ch211-149b19.4
chr5_-_20678300 1.24 ENSDART00000088639
wscd2
WSC domain containing 2
chr10_-_35542071 1.24 ENSDART00000162139
si:ch211-244c8.4
si:ch211-244c8.4
chr4_-_75175407 1.22 ENSDART00000180125
CABZ01043953.1

chr18_+_9641210 1.21 ENSDART00000182024
pclob
piccolo presynaptic cytomatrix protein b
chr10_+_29963518 1.11 ENSDART00000011317
ENSDART00000099964
ENSDART00000182990
ENSDART00000113912
ntm
neurotrimin
chr1_-_19845378 1.09 ENSDART00000139314
ENSDART00000132958
ENSDART00000147502
grhprb
glyoxylate reductase/hydroxypyruvate reductase b
chr15_+_16525126 1.08 ENSDART00000193455
galnt17
polypeptide N-acetylgalactosaminyltransferase 17
chr19_+_9050852 1.06 ENSDART00000151031
ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr20_-_915234 1.05 ENSDART00000164816
cnr1
cannabinoid receptor 1
chr1_-_17797802 1.04 ENSDART00000041215
sorbs2a
sorbin and SH3 domain containing 2a
chr1_-_46862190 1.04 ENSDART00000145167
agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr25_+_30298377 1.02 ENSDART00000153622
C11orf96
chromosome 11 open reading frame 96
chr18_+_9635178 1.00 ENSDART00000183486
pclob
piccolo presynaptic cytomatrix protein b
chr6_+_54358529 0.99 ENSDART00000153704
anks1ab
ankyrin repeat and sterile alpha motif domain containing 1Ab
chr22_-_10487490 0.93 ENSDART00000064798
aspn
asporin (LRR class 1)
chr4_+_5132951 0.92 ENSDART00000103279
ccnd2b
cyclin D2, b
chr16_-_31644545 0.90 ENSDART00000181634
CR855311.5

chr1_+_9557212 0.89 ENSDART00000111131
elfn1b
extracellular leucine-rich repeat and fibronectin type III domain containing 1b
chr5_-_17876709 0.88 ENSDART00000141978
si:dkey-112e17.1
si:dkey-112e17.1
chr7_-_2129076 0.87 ENSDART00000182385
si:cabz01007807.1
si:cabz01007807.1
chr11_+_30314885 0.87 ENSDART00000187418
ENSDART00000123244
ugt1b2
UDP glucuronosyltransferase 1 family, polypeptide B2
chr12_+_24562667 0.86 ENSDART00000056256
nrxn1a
neurexin 1a
chr16_+_42667560 0.86 ENSDART00000023452
dpy19l1l
dpy-19-like 1, like (H. sapiens)
chr16_+_37470717 0.84 ENSDART00000112003
ENSDART00000188431
ENSDART00000192837
adgrb1a
adhesion G protein-coupled receptor B1a
chr2_+_50738325 0.80 ENSDART00000114182
fyco1b
FYVE and coiled-coil domain containing 1b
chr22_+_38173960 0.80 ENSDART00000010537
cp
ceruloplasmin
chr8_-_47800754 0.80 ENSDART00000115050
ENSDART00000133669
kank3
KN motif and ankyrin repeat domains 3
chr5_+_13521081 0.79 ENSDART00000171975
si:ch211-230g14.6
si:ch211-230g14.6
chr9_-_46072805 0.79 ENSDART00000169682
hdac4
histone deacetylase 4
chr8_+_31119548 0.79 ENSDART00000136578
syn1
synapsin I
chr2_-_30784198 0.78 ENSDART00000182523
ENSDART00000147355
rgs20
regulator of G protein signaling 20
chr3_-_46410387 0.78 ENSDART00000156822
cdip1
cell death-inducing p53 target 1
chr5_+_36768674 0.75 ENSDART00000146854
mark4a
MAP/microtubule affinity-regulating kinase 4a
chr18_+_16963881 0.74 ENSDART00000147583
si:ch211-242e8.1
si:ch211-242e8.1
chr7_+_73780936 0.73 ENSDART00000092691
pea15
proliferation and apoptosis adaptor protein 15
chr25_-_28384954 0.71 ENSDART00000073500
ptprz1a
protein tyrosine phosphatase, receptor-type, Z polypeptide 1a
chr4_-_2219705 0.68 ENSDART00000131046
si:ch73-278m9.1
si:ch73-278m9.1
chr5_-_58112032 0.68 ENSDART00000016418
drd2b
dopamine receptor D2b
chr17_+_30587333 0.65 ENSDART00000156500
nhsl1a
NHS-like 1a
chr21_-_30935262 0.63 ENSDART00000172390
stim1b
stromal interaction molecule 1b
chr17_-_7371564 0.62 ENSDART00000060336
rab32b
RAB32b, member RAS oncogene family
chr8_-_40075983 0.62 ENSDART00000141455
ggt1a
gamma-glutamyltransferase 1a
chr19_+_32201991 0.62 ENSDART00000022667
fam8a1a
family with sequence similarity 8, member A1a
chr8_+_47342586 0.61 ENSDART00000007624
plch2a
phospholipase C, eta 2a
chr14_+_25464681 0.61 ENSDART00000067500
ENSDART00000187601
si:dkey-280e21.3
si:dkey-280e21.3
chr6_+_10094061 0.60 ENSDART00000150998
ENSDART00000162236
atp7b
ATPase copper transporting beta
chr16_-_4026265 0.59 ENSDART00000149339
si:ch211-175f12.2
si:ch211-175f12.2
chr5_+_36439405 0.58 ENSDART00000102973
eda
ectodysplasin A
chr8_-_49201258 0.58 ENSDART00000114584
ENSDART00000142172
zgc:171501
zgc:171501
chr20_-_38610360 0.58 ENSDART00000168783
ENSDART00000164638
slc30a2
solute carrier family 30 (zinc transporter), member 2
chr2_+_54086436 0.57 ENSDART00000174581
CU179656.1

chr10_-_44411032 0.56 ENSDART00000111509
CABZ01072096.1

chr10_+_2232023 0.55 ENSDART00000097695
cntnap3
contactin associated protein like 3
chr7_-_15413019 0.55 ENSDART00000172147
si:ch211-106j24.1
si:ch211-106j24.1
chr8_-_18316482 0.53 ENSDART00000190156
rnf220b
ring finger protein 220b
chr16_+_50741154 0.53 ENSDART00000101627
IGLON5
zgc:110372
chr12_-_46145635 0.50 ENSDART00000074682
zgc:153932
zgc:153932
chr8_-_7078575 0.50 ENSDART00000137413
si:ch73-233m11.2
si:ch73-233m11.2
chr25_+_7461624 0.50 ENSDART00000170569
syt12
synaptotagmin XII
chr1_+_7956030 0.50 ENSDART00000159655
CR855320.1

chr17_+_31580960 0.49 ENSDART00000188157
si:dkey-13p1.4
si:dkey-13p1.4
chr20_-_35052823 0.47 ENSDART00000153033
kif26bb
kinesin family member 26Bb
chr13_-_15799391 0.47 ENSDART00000124688
bag5
BCL2 associated athanogene 5
chr21_+_22985078 0.46 ENSDART00000156491
lpar6b
lysophosphatidic acid receptor 6b
chr2_+_47718605 0.46 ENSDART00000189180
ENSDART00000148824
mbnl1
muscleblind-like splicing regulator 1
chr3_-_19091024 0.45 ENSDART00000188485
ENSDART00000110554
grin2ca
glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca
chr20_-_7000225 0.43 ENSDART00000100098
adcy1a
adenylate cyclase 1a
chr2_+_48638827 0.43 ENSDART00000163634
CR381673.2

chr5_+_20437124 0.43 ENSDART00000159001
tmem119a
transmembrane protein 119a
chr14_+_46020282 0.42 ENSDART00000190087
c1qtnf2
C1q and TNF related 2
chr21_-_5856050 0.42 ENSDART00000115367
CABZ01071020.1

chr3_+_5083407 0.41 ENSDART00000146883
si:ch73-338o16.4
si:ch73-338o16.4
chr12_-_26582607 0.41 ENSDART00000045186
slc16a5a
solute carrier family 16 (monocarboxylate transporter), member 5a
chr7_+_73801377 0.40 ENSDART00000184051
si:ch73-252p3.1
si:ch73-252p3.1
chr19_+_56351 0.40 ENSDART00000168334
col14a1b
collagen, type XIV, alpha 1b
chr6_+_7123980 0.40 ENSDART00000179738
ENSDART00000151311
si:ch211-237c6.4
si:ch211-237c6.4
chr14_+_25465346 0.40 ENSDART00000173436
si:dkey-280e21.3
si:dkey-280e21.3
chr10_+_26747755 0.39 ENSDART00000100329
f9b
coagulation factor IXb
chr22_-_188102 0.39 ENSDART00000125391
ENSDART00000170463
CABZ01052268.1

chr3_-_18805225 0.38 ENSDART00000133471
ENSDART00000131758
msrb1a
methionine sulfoxide reductase B1a
chr7_-_15413188 0.37 ENSDART00000185980
si:ch211-106j24.1
si:ch211-106j24.1
chr20_+_10498704 0.37 ENSDART00000192985
zgc:100997
zgc:100997
chr24_-_39354829 0.36 ENSDART00000169108
kcnj12a
potassium inwardly-rectifying channel, subfamily J, member 12a
chr21_-_26520629 0.35 ENSDART00000142731
rce1b
Ras converting CAAX endopeptidase 1b
chr20_-_6131686 0.35 ENSDART00000145964
ENSDART00000086578
ENSDART00000164090
pum2
pumilio RNA-binding family member 2
chr9_-_11655031 0.34 ENSDART00000044314
itgav
integrin, alpha V
chr17_-_34952562 0.33 ENSDART00000021128
kidins220a
kinase D-interacting substrate 220a
chr15_+_42431198 0.33 ENSDART00000189951
ENSDART00000089694
tiam1b
T cell lymphoma invasion and metastasis 1b
chr4_-_38476901 0.32 ENSDART00000167124
si:ch211-209n20.59
si:ch211-209n20.59
chr17_-_8562586 0.32 ENSDART00000154257
ENSDART00000157308
fzd3b
frizzled class receptor 3b
chr25_+_32473433 0.30 ENSDART00000152326
sqor
sulfide quinone oxidoreductase
chr10_-_24868581 0.29 ENSDART00000193055
CABZ01058107.1

chr18_+_22793743 0.29 ENSDART00000150106
gnao1a
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a
chr15_-_19128705 0.27 ENSDART00000152428
arhgap32a
Rho GTPase activating protein 32a
chr13_-_45201300 0.27 ENSDART00000074750
ENSDART00000180265
runx3
runt-related transcription factor 3
chr19_-_26235219 0.27 ENSDART00000104008
dtnbp1b
dystrobrevin binding protein 1b
chr23_-_41824460 0.26 ENSDART00000131235
GMEB2
si:ch73-302a13.2
chr4_+_4902392 0.24 ENSDART00000133866
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr9_-_33136990 0.22 ENSDART00000131742
slc5a3b
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3b
chr11_-_23025949 0.22 ENSDART00000184859
ENSDART00000167818
ENSDART00000046122
ENSDART00000193120
atp2b2
ATPase plasma membrane Ca2+ transporting 2
chr14_-_41091667 0.22 ENSDART00000170042
drp2
dystrophin related protein 2
chr24_-_6258869 0.22 ENSDART00000006636
ENSDART00000178667
myo3a
myosin IIIA
chr6_-_15639087 0.21 ENSDART00000128940
ENSDART00000183092
mlpha
melanophilin a
chr10_+_18952271 0.21 ENSDART00000146517
dpysl2b
dihydropyrimidinase-like 2b
chr23_-_14057191 0.21 ENSDART00000154908
adcy6a
adenylate cyclase 6a
chr25_+_22730490 0.21 ENSDART00000149455
abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr3_+_57991074 0.21 ENSDART00000076077
myadml2
myeloid-associated differentiation marker-like 2
chr7_+_34790768 0.18 ENSDART00000075116
si:dkey-148a17.6
si:dkey-148a17.6
chr11_+_36355348 0.18 ENSDART00000145427
sypl2a
synaptophysin-like 2a
chr25_-_24247584 0.17 ENSDART00000046349
spty2d1
SPT2 chromatin protein domain containing 1
chr17_-_4252221 0.17 ENSDART00000152020
gdf3
growth differentiation factor 3
chr3_+_56574623 0.17 ENSDART00000130877
rac1b
Rac family small GTPase 1b
chr20_-_35052464 0.15 ENSDART00000037195
kif26bb
kinesin family member 26Bb
chr24_-_25184553 0.15 ENSDART00000166917
plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr14_+_30774515 0.15 ENSDART00000191666
atl3
atlastin 3
chr11_+_440305 0.15 ENSDART00000082517
rab43
RAB43, member RAS oncogene family
chr8_-_14484599 0.14 ENSDART00000057644
lhx4
LIM homeobox 4
chr19_+_7954679 0.14 ENSDART00000150909
si:dkey-266f7.10
si:dkey-266f7.10
chr21_-_38619305 0.13 ENSDART00000139178
slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr18_-_17485419 0.12 ENSDART00000018764
foxl1
forkhead box L1
chr7_-_8374950 0.12 ENSDART00000057101
aep1
aerolysin-like protein
chr10_+_40235959 0.12 ENSDART00000145862
gramd1ba
GRAM domain containing 1Ba
chr1_+_10129099 0.11 ENSDART00000187740
rbm46
RNA binding motif protein 46
chr8_+_28467893 0.11 ENSDART00000189724
slc52a3
solute carrier family 52 (riboflavin transporter), member 3
chr14_+_49152341 0.11 ENSDART00000084114
nsd1a
nuclear receptor binding SET domain protein 1a
chr5_-_23715861 0.10 ENSDART00000019992
gbgt1l1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr5_+_20599658 0.10 ENSDART00000143019
CMKLR1 (1 of many)
si:ch211-240b21.4
chr3_-_51109286 0.09 ENSDART00000172010
si:ch211-148f13.1
si:ch211-148f13.1
chr17_+_6563307 0.09 ENSDART00000156454
adgrf3a
adhesion G protein-coupled receptor F3a
chr16_-_7827517 0.09 ENSDART00000189975
tcaim
T cell activation inhibitor, mitochondrial
chr22_+_38762693 0.09 ENSDART00000015016
ENSDART00000150187
alpi.1
alkaline phosphatase, intestinal, tandem duplicate 1
chr24_+_7828613 0.08 ENSDART00000135161
zgc:101569
zgc:101569
chr20_+_2669017 0.08 ENSDART00000058777
slc35a1
solute carrier family 35 (CMP-sialic acid transporter), member A1
chr6_-_8480815 0.08 ENSDART00000162300
rasal3
RAS protein activator like 3
chr13_-_865193 0.07 ENSDART00000187053
AL929536.7

chr24_-_10828560 0.05 ENSDART00000132282
fam49bb
family with sequence similarity 49, member Bb
chr5_-_31926906 0.05 ENSDART00000187340
ssh1b
slingshot protein phosphatase 1b
chr14_-_215051 0.04 ENSDART00000054822
nkx3.2
NK3 homeobox 2
chr9_-_12736089 0.04 ENSDART00000088042
myo10l3
myosin X-like 3
chr14_+_30774032 0.04 ENSDART00000139552
atl3
atlastin 3
chr21_+_35327589 0.03 ENSDART00000145191
ENSDART00000132743
rars
arginyl-tRNA synthetase
chr4_+_38937575 0.02 ENSDART00000150385
znf997
zinc finger protein 997
chr22_+_1751640 0.02 ENSDART00000162093
znf1169
zinc finger protein 1169
chr16_-_37964325 0.01 ENSDART00000148801
mrap2a
melanocortin 2 receptor accessory protein 2a
chr20_+_26095530 0.01 ENSDART00000139350
syne1a
spectrin repeat containing, nuclear envelope 1a
chr4_+_64921810 0.00 ENSDART00000157654
BX928743.1

Network of associatons between targets according to the STRING database.

First level regulatory network of gli2a+gli3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.3 0.9 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.2 2.2 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.2 0.8 GO:0090299 regulation of neural crest formation(GO:0090299)
0.2 2.2 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.2 1.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 0.8 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.4 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.1 1.0 GO:0038171 cannabinoid signaling pathway(GO:0038171) positive regulation of feeding behavior(GO:2000253)
0.1 0.6 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.4 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 0.6 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 0.6 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.6 GO:0031179 peptide modification(GO:0031179)
0.1 0.3 GO:0033363 secretory granule organization(GO:0033363) platelet dense granule organization(GO:0060155)
0.1 1.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 1.3 GO:0014823 response to activity(GO:0014823)
0.1 0.7 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 0.2 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 0.9 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 0.3 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 0.2 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 2.5 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.7 GO:0051967 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.9 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.0 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.2 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 7.2 GO:0007601 visual perception(GO:0007601)
0.0 0.6 GO:0032438 melanosome organization(GO:0032438)
0.0 1.0 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 1.4 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.8 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.1 GO:0015744 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.5 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.5 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 1.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.3 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 0.8 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.6 GO:0042476 odontogenesis(GO:0042476)
0.0 1.4 GO:0014904 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 0.6 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 0.5 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.1 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.8 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.2 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 1.6 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.1 GO:0016586 RSC complex(GO:0016586)
0.1 1.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 2.0 GO:0043195 terminal bouton(GO:0043195)
0.1 1.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 1.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.3 GO:0001650 fibrillar center(GO:0001650)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.7 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.8 GO:0005776 autophagosome(GO:0005776)
0.0 0.8 GO:0000118 histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.0 GO:0032052 bile acid binding(GO:0032052)
0.4 1.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3 1.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 1.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.2 0.7 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 2.2 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 2.2 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.6 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.4 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.1 1.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.6 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 0.2 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.1 0.3 GO:0031852 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.8 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.8 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 1.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.7 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 1.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.1 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.6 GO:0030546 death receptor binding(GO:0005123) receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.9 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 2.6 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.9 GO:0005518 collagen binding(GO:0005518)
0.0 1.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 1.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.1 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.8 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 2.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 2.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels