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PRJEB1986: zebrafish developmental stages transcriptome

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Results for gmeb2

Z-value: 0.61

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Transcription factors associated with gmeb2

Gene Symbol Gene ID Gene Info
gmeb2
ENSDARG00000093240 si_ch73-302a13.2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GMEB2dr11_v1_chr23_-_41824460_41824460-0.725.1e-04Click!

Activity profile of gmeb2 motif

Sorted Z-values of gmeb2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_20195350 3.28 ENSDART00000139675
dao.1
D-amino-acid oxidase, tandem duplicate 1
chr5_-_67365333 1.62 ENSDART00000133438
unga
uracil DNA glycosylase a
chr14_+_10625112 1.60 ENSDART00000143377
ENSDART00000136480
nup62l
nucleoporin 62 like
chr2_-_17114852 1.49 ENSDART00000006549
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr21_+_6397463 1.45 ENSDART00000136539
si:ch211-225g23.1
si:ch211-225g23.1
chr5_+_26138313 1.41 ENSDART00000010041
dhfr
dihydrofolate reductase
chr3_-_49382896 1.36 ENSDART00000169115
si:ch73-167f10.1
si:ch73-167f10.1
chr10_-_17484762 1.20 ENSDART00000137905
ENSDART00000007961
nt5c2l1
5'-nucleotidase, cytosolic II, like 1
chr16_+_40131473 1.12 ENSDART00000155421
ENSDART00000134732
ENSDART00000138699
cenpw
si:ch211-195p4.4
centromere protein W
si:ch211-195p4.4
chr11_-_36475124 1.12 ENSDART00000165203
usp48
ubiquitin specific peptidase 48
chr12_-_43685802 1.07 ENSDART00000170723
zgc:112964
zgc:112964
chr2_+_56012016 0.94 ENSDART00000146160
ENSDART00000188702
loxl5b
lysyl oxidase-like 5b
chr17_-_31611692 0.93 ENSDART00000141480
si:dkey-170l10.1
si:dkey-170l10.1
chr6_-_52675630 0.92 ENSDART00000083830
sdc4
syndecan 4
chr2_-_17115256 0.92 ENSDART00000190488
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr25_+_21098990 0.91 ENSDART00000017488
rad52
RAD52 homolog, DNA repair protein
chr16_+_14201401 0.90 ENSDART00000113679
dap3
death associated protein 3
chr10_-_14545658 0.90 ENSDART00000057865
ier3ip1
immediate early response 3 interacting protein 1
chr7_-_39751540 0.86 ENSDART00000016803
grpel1
GrpE-like 1, mitochondrial
chr8_+_13064750 0.85 ENSDART00000039878
sap30bp
SAP30 binding protein
chr12_+_45238292 0.85 ENSDART00000057983
mrpl38
mitochondrial ribosomal protein L38
chr2_-_42128714 0.84 ENSDART00000047055
trim55a
tripartite motif containing 55a
chr2_-_21170517 0.82 ENSDART00000135417
bmi1b
bmi1 polycomb ring finger oncogene 1b
chr20_-_39367895 0.81 ENSDART00000136476
ENSDART00000021788
ENSDART00000180784
pbk
PDZ binding kinase
chr5_-_16139600 0.80 ENSDART00000051644
coq5
coenzyme Q5, methyltransferase
chr8_+_10304981 0.79 ENSDART00000160766
pim1
Pim-1 proto-oncogene, serine/threonine kinase
chr6_-_40455109 0.77 ENSDART00000103878
vhl
von Hippel-Lindau tumor suppressor
chr7_+_41313568 0.76 ENSDART00000016660
zgc:165532
zgc:165532
chr22_-_26353916 0.76 ENSDART00000077958
capn2b
calpain 2, (m/II) large subunit b
chr1_-_23274038 0.75 ENSDART00000181658
rfc1
replication factor C (activator 1) 1
chr9_+_19529951 0.75 ENSDART00000125416
pknox1.1
pbx/knotted 1 homeobox 1.1
chr3_+_22335030 0.75 ENSDART00000055676
zgc:103564
zgc:103564
chr25_-_21066136 0.74 ENSDART00000109520
fbxl14a
F-box and leucine-rich repeat protein 14a
chr2_+_10821127 0.74 ENSDART00000145770
ENSDART00000174629
ENSDART00000081094
glmna
glomulin, FKBP associated protein a
chr25_+_21098675 0.74 ENSDART00000079012
rad52
RAD52 homolog, DNA repair protein
chr7_-_7493758 0.73 ENSDART00000036703
pfdn2
prefoldin subunit 2
chr6_-_39275793 0.73 ENSDART00000180477
ENSDART00000148531
arhgef25b
Rho guanine nucleotide exchange factor (GEF) 25b
chr1_-_23274393 0.72 ENSDART00000147800
ENSDART00000130277
ENSDART00000054340
ENSDART00000054338
rpl9
ribosomal protein L9
chr22_-_621888 0.72 ENSDART00000135829
srsf3b
serine/arginine-rich splicing factor 3b
chr4_+_23126558 0.71 ENSDART00000162859
mdm2
MDM2 oncogene, E3 ubiquitin protein ligase
chr2_+_2168547 0.71 ENSDART00000029347
higd1a
HIG1 hypoxia inducible domain family, member 1A
chr4_-_12914163 0.70 ENSDART00000140002
ENSDART00000145917
ENSDART00000141355
ENSDART00000067135
msrb3
methionine sulfoxide reductase B3
chr24_+_39638555 0.69 ENSDART00000078313
luc7l
LUC7-like (S. cerevisiae)
chr2_+_10821579 0.67 ENSDART00000179694
glmna
glomulin, FKBP associated protein a
chr16_+_23397785 0.66 ENSDART00000148961
s100a10b
S100 calcium binding protein A10b
chr8_-_4760723 0.66 ENSDART00000064201
cdc45
CDC45 cell division cycle 45 homolog (S. cerevisiae)
chr1_+_9860381 0.66 ENSDART00000054848
pmm2
phosphomannomutase 2
chr1_+_51479128 0.66 ENSDART00000028018
meis1a
Meis homeobox 1 a
chr10_+_22034477 0.65 ENSDART00000133304
ENSDART00000134189
ENSDART00000021240
ENSDART00000100526
npm1a
nucleophosmin 1a
chr2_-_20923864 0.65 ENSDART00000006870
ptgs2a
prostaglandin-endoperoxide synthase 2a
chr19_+_40026041 0.65 ENSDART00000017359
sfpq
splicing factor proline/glutamine-rich
chr7_+_51795667 0.64 ENSDART00000174201
ENSDART00000073839
slc38a7
solute carrier family 38, member 7
chr5_-_67365006 0.64 ENSDART00000136116
unga
uracil DNA glycosylase a
chr11_-_22372072 0.62 ENSDART00000065996
tmem183a
transmembrane protein 183A
chr16_-_47427016 0.62 ENSDART00000074575
sept7b
septin 7b
chr1_-_26063188 0.62 ENSDART00000168640
pdcd4a
programmed cell death 4a
chr12_+_28956374 0.62 ENSDART00000033878
znf668
zinc finger protein 668
chr4_-_11810365 0.61 ENSDART00000150529
cyb5r3
cytochrome b5 reductase 3
chr17_-_51818659 0.61 ENSDART00000111389
ENSDART00000157244
exd2
exonuclease 3'-5' domain containing 2
chr6_-_39903393 0.60 ENSDART00000085945
tsfm
Ts translation elongation factor, mitochondrial
chr23_-_33558161 0.58 ENSDART00000018301
itga5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr7_+_66634167 0.57 ENSDART00000027616
eif4g2a
eukaryotic translation initiation factor 4, gamma 2a
chr16_+_41015163 0.57 ENSDART00000058586
dek
DEK proto-oncogene
chr16_+_31921812 0.56 ENSDART00000176928
ENSDART00000193733
rps9
ribosomal protein S9
chr13_+_42309688 0.56 ENSDART00000158367
ide
insulin-degrading enzyme
chr6_-_10728057 0.56 ENSDART00000002247
sp3b
Sp3b transcription factor
chr2_+_32826235 0.55 ENSDART00000143127
si:dkey-154p10.3
si:dkey-154p10.3
chr1_-_31516091 0.55 ENSDART00000139828
ENSDART00000146567
cenpk
centromere protein K
chr17_-_49407091 0.53 ENSDART00000021950
mthfd1b
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr13_+_3938526 0.53 ENSDART00000012759
yipf3
Yip1 domain family, member 3
chr9_-_23242684 0.53 ENSDART00000053282
ENSDART00000179770
ccnt2a
cyclin T2a
chr11_-_14813029 0.52 ENSDART00000004920
ENSDART00000122645
sgta
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr8_+_10305400 0.52 ENSDART00000172400
pim1
Pim-1 proto-oncogene, serine/threonine kinase
chr2_+_38055529 0.52 ENSDART00000145642
si:rp71-1g18.1
si:rp71-1g18.1
chr4_-_11810799 0.52 ENSDART00000014153
cyb5r3
cytochrome b5 reductase 3
chr9_+_21819082 0.51 ENSDART00000136902
ENSDART00000101991
txndc9
thioredoxin domain containing 9
chr12_+_33460794 0.51 ENSDART00000007053
ENSDART00000142716
narf
nuclear prelamin A recognition factor
chr1_-_26062798 0.51 ENSDART00000185348
pdcd4a
programmed cell death 4a
chr15_-_23692359 0.50 ENSDART00000141618
ercc2
excision repair cross-complementation group 2
chr6_-_37745508 0.50 ENSDART00000078316
nipa2
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr23_+_20640484 0.50 ENSDART00000054691
uba1
ubiquitin-like modifier activating enzyme 1
chr5_-_54395488 0.48 ENSDART00000160781
zmynd19
zinc finger, MYND-type containing 19
chr23_-_33738570 0.48 ENSDART00000131680
si:ch211-210c8.7
si:ch211-210c8.7
chr23_-_33738945 0.46 ENSDART00000136386
si:ch211-210c8.7
si:ch211-210c8.7
chr18_-_14879135 0.46 ENSDART00000099701
selenoo1
selenoprotein O1
chr9_+_25840720 0.46 ENSDART00000024572
gtdc1
glycosyltransferase-like domain containing 1
chr8_-_30944465 0.45 ENSDART00000128792
ENSDART00000191717
ENSDART00000049944
smarcb1a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1a
chr1_+_23274710 0.45 ENSDART00000036448
lias
lipoic acid synthetase
chr10_+_28428222 0.45 ENSDART00000135003
si:ch211-222e20.4
si:ch211-222e20.4
chr22_-_817479 0.44 ENSDART00000123487
zgc:153675
zgc:153675
chr7_+_55292959 0.44 ENSDART00000147539
ENSDART00000073555
ctu2
cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr13_+_30035253 0.44 ENSDART00000181303
ENSDART00000057525
ENSDART00000136622
dnajb12a
DnaJ (Hsp40) homolog, subfamily B, member 12a
chr8_+_20455134 0.43 ENSDART00000079618
rexo1
REX1, RNA exonuclease 1 homolog
chr14_-_21932403 0.43 ENSDART00000054420
rad9a
RAD9 checkpoint clamp component A
chr20_-_37933237 0.42 ENSDART00000142567
ENSDART00000036371
ENSDART00000061445
angel2
angel homolog 2 (Drosophila)
chr22_-_22301929 0.42 ENSDART00000142027
chaf1a
chromatin assembly factor 1, subunit A (p150)
chr13_-_36535128 0.42 ENSDART00000043312
srsf5a
serine/arginine-rich splicing factor 5a
chr7_-_23894879 0.42 ENSDART00000123203
vbp1
von Hippel-Lindau binding protein 1
chr12_+_638435 0.42 ENSDART00000152508
si:ch211-176g6.1
si:ch211-176g6.1
chr5_-_23596339 0.41 ENSDART00000024815
fam76b
family with sequence similarity 76, member B
chr18_+_49248389 0.40 ENSDART00000059285
ENSDART00000142004
ENSDART00000132751
yif1b
Yip1 interacting factor homolog B (S. cerevisiae)
chr22_+_20145036 0.40 ENSDART00000137624
eef2a.2
eukaryotic translation elongation factor 2a, tandem duplicate 2
chr21_-_44772738 0.39 ENSDART00000026178
kif4
kinesin family member 4
chr13_+_36923052 0.39 ENSDART00000026313
tmx1
thioredoxin-related transmembrane protein 1
chr20_-_36809059 0.39 ENSDART00000062925
slc25a27
solute carrier family 25, member 27
chr15_-_31406093 0.38 ENSDART00000123444
or111-8
odorant receptor, family D, subfamily 111, member 8
chr17_+_37932433 0.38 ENSDART00000185349
plekhh1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr25_-_8513255 0.38 ENSDART00000150129
polg
polymerase (DNA directed), gamma
chr5_-_12063381 0.38 ENSDART00000026749
nipsnap1
nipsnap homolog 1 (C. elegans)
chr13_+_21676235 0.38 ENSDART00000137804
ENSDART00000134950
ENSDART00000129653
mtg1
mitochondrial ribosome-associated GTPase 1
chr1_+_49415281 0.37 ENSDART00000015007
taf5
TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr13_-_12486076 0.37 ENSDART00000146195
lamtor3
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
chr4_+_9011448 0.37 ENSDART00000192357
samm50l
sorting and assembly machinery component 50 homolog, like
chr9_-_23747264 0.36 ENSDART00000141461
ENSDART00000010311
ndufa10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10
chr12_+_17603528 0.36 ENSDART00000111565
pms2
PMS1 homolog 2, mismatch repair system component
chr2_+_52049239 0.35 ENSDART00000036813
ccdc94
coiled-coil domain containing 94
chr3_+_26342768 0.35 ENSDART00000163832
si:ch211-156b7.4
si:ch211-156b7.4
chr5_+_25585869 0.35 ENSDART00000138060
si:dkey-229d2.7
si:dkey-229d2.7
chr24_-_7826489 0.34 ENSDART00000112777
si:dkey-197c15.6
si:dkey-197c15.6
chr3_+_53156813 0.34 ENSDART00000114343
brd4
bromodomain containing 4
chr10_+_20070178 0.34 ENSDART00000027612
ENSDART00000145264
ENSDART00000172713
xpo7
exportin 7
chr20_-_9199721 0.34 ENSDART00000064140
ylpm1
YLP motif containing 1
chr3_+_46764022 0.34 ENSDART00000023814
prkcsh
protein kinase C substrate 80K-H
chr15_+_32798333 0.33 ENSDART00000162370
ENSDART00000166525
spartb
spartin b
chr7_+_52761841 0.32 ENSDART00000111444
ppip5k1a
diphosphoinositol pentakisphosphate kinase 1a
chr25_-_28668776 0.32 ENSDART00000126490
fnbp4
formin binding protein 4
chr15_-_43284021 0.32 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr2_-_32486080 0.32 ENSDART00000110821
ttc19
tetratricopeptide repeat domain 19
chr17_-_48805159 0.31 ENSDART00000103662
kif6
kinesin family member 6
chr17_-_6451801 0.31 ENSDART00000064700
fuca2
alpha-L-fucosidase 2
chr18_-_40481028 0.30 ENSDART00000134177
zgc:101040
zgc:101040
chr22_-_621609 0.30 ENSDART00000137264
ENSDART00000106636
srsf3b
serine/arginine-rich splicing factor 3b
chr8_-_4618653 0.29 ENSDART00000025535
sept5a
septin 5a
chr3_+_59880317 0.29 ENSDART00000166922
ENSDART00000108647
alyref
Aly/REF export factor
chr17_-_36860988 0.29 ENSDART00000154981
senp6b
SUMO1/sentrin specific peptidase 6b
chr8_+_53311965 0.29 ENSDART00000130104
gnb1a
guanine nucleotide binding protein (G protein), beta polypeptide 1a
chr20_-_32405440 0.28 ENSDART00000062978
ENSDART00000153411
afg1lb
AFG1 like ATPase b
chr15_+_5116179 0.28 ENSDART00000101937
pgm2l1
phosphoglucomutase 2-like 1
chr20_-_31743817 0.28 ENSDART00000137679
sash1a
SAM and SH3 domain containing 1a
chr3_+_46763745 0.28 ENSDART00000185437
prkcsh
protein kinase C substrate 80K-H
chr3_-_25814097 0.27 ENSDART00000169706
ntn1b
netrin 1b
chr18_-_20674121 0.27 ENSDART00000005145
asz1
ankyrin repeat, SAM and basic leucine zipper domain containing 1
chr9_+_23049500 0.26 ENSDART00000012478
mmadhc
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr23_+_17522867 0.26 ENSDART00000002714
slc17a9b
solute carrier family 17 (vesicular nucleotide transporter), member 9b
chr18_+_30847237 0.25 ENSDART00000012374
foxf1
forkhead box F1
chr12_+_11650146 0.25 ENSDART00000150191
waplb
WAPL cohesin release factor b
chr12_-_27588299 0.25 ENSDART00000178023
ENSDART00000066282
dhx8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr17_-_12058171 0.25 ENSDART00000105236
smyd3
SET and MYND domain containing 3
chr20_+_38837238 0.24 ENSDART00000061334
ift172
intraflagellar transport 172
chr16_-_47426482 0.24 ENSDART00000148631
ENSDART00000149723
sept7b
septin 7b
chr6_-_51541488 0.23 ENSDART00000156336
si:dkey-6e2.2
si:dkey-6e2.2
chr8_-_32354677 0.23 ENSDART00000138268
ENSDART00000133245
ENSDART00000179677
ENSDART00000174450
ipo11
importin 11
chr16_-_20294236 0.23 ENSDART00000059623
plekha8
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
chr1_+_26105141 0.21 ENSDART00000102379
ENSDART00000127154
toporsa
topoisomerase I binding, arginine/serine-rich a
chr17_+_12058509 0.21 ENSDART00000150209
tfb2m
transcription factor B2, mitochondrial
chr8_+_1239 0.21 ENSDART00000067666
ENSDART00000192564
ENSDART00000192612
ENSDART00000190683
tmed7
transmembrane p24 trafficking protein 7
chr16_-_29557338 0.21 ENSDART00000058888
hormad1
HORMA domain containing 1
chr14_-_30808174 0.20 ENSDART00000173262
prss23
protease, serine, 23
chr22_-_22301672 0.19 ENSDART00000111711
chaf1a
chromatin assembly factor 1, subunit A (p150)
chr15_-_31364729 0.19 ENSDART00000185386
or111-2
odorant receptor, family D, subfamily 111, member 2
chr4_+_8638622 0.19 ENSDART00000186829
wnt5b
wingless-type MMTV integration site family, member 5b
chr25_-_6389713 0.19 ENSDART00000083539
sin3aa
SIN3 transcription regulator family member Aa
chr1_-_49521407 0.19 ENSDART00000189845
ENSDART00000143474
zp3c
zona pellucida glycoprotein 3c
chr4_+_9011825 0.19 ENSDART00000058007
samm50l
sorting and assembly machinery component 50 homolog, like
chr11_+_24298432 0.19 ENSDART00000138487
si:dkey-76p14.2
si:dkey-76p14.2
chr17_-_25831569 0.18 ENSDART00000148743
hhat
hedgehog acyltransferase
chr12_-_10409961 0.17 ENSDART00000149521
ENSDART00000052001
eef2k
eukaryotic elongation factor 2 kinase
chr7_-_55539738 0.17 ENSDART00000168721
ENSDART00000013796
ENSDART00000148514
aprt
adenine phosphoribosyltransferase
chr8_-_19467011 0.17 ENSDART00000162010
zgc:92140
zgc:92140
chr22_+_24214665 0.17 ENSDART00000163980
ENSDART00000167996
glrx2
glutaredoxin 2
chr11_+_43419809 0.17 ENSDART00000172982
slc29a1b
solute carrier family 29 (equilibrative nucleoside transporter), member 1b
chr14_+_8947282 0.16 ENSDART00000047993
rps6kal
ribosomal protein S6 kinase a, like
chr14_-_43000836 0.16 ENSDART00000162714
pcdh10b
protocadherin 10b
chr3_+_46764278 0.16 ENSDART00000136051
ENSDART00000164930
prkcsh
protein kinase C substrate 80K-H
chr11_-_44945636 0.15 ENSDART00000157658
orc2
origin recognition complex, subunit 2
chr12_+_3571770 0.14 ENSDART00000164707
ENSDART00000189819
coa3a
cytochrome C oxidase assembly factor 3a
chr16_-_17300030 0.14 ENSDART00000149267
kel
Kell blood group, metallo-endopeptidase
chr7_-_38570878 0.14 ENSDART00000139187
ENSDART00000134570
ENSDART00000041055
celf1
cugbp, Elav-like family member 1
chr20_-_20410029 0.13 ENSDART00000192177
ENSDART00000063483
prkchb
protein kinase C, eta, b
chr13_-_21688176 0.13 ENSDART00000063825
sprn
shadow of prion protein
chr15_+_11683114 0.13 ENSDART00000168233
si:dkey-31c13.1
si:dkey-31c13.1
chr6_+_46668717 0.12 ENSDART00000064853
oxtrl
oxytocin receptor like
chr5_+_24245682 0.12 ENSDART00000049003
atp6v1aa
ATPase H+ transporting V1 subunit Aa
chr6_-_1223551 0.11 ENSDART00000182112
CABZ01063034.1

chr24_+_37484661 0.11 ENSDART00000165125
ENSDART00000109221
wdr90
WD repeat domain 90
chr6_-_25201810 0.11 ENSDART00000168683
lrrc8c
leucine rich repeat containing 8 VRAC subunit C
chr2_+_26647472 0.10 ENSDART00000145415
ENSDART00000157409
ttpa
tocopherol (alpha) transfer protein
chr12_-_11649690 0.10 ENSDART00000149713
btbd16
BTB (POZ) domain containing 16
chr11_-_41132296 0.10 ENSDART00000162944
dnajc11b
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr8_+_30112655 0.10 ENSDART00000099027
fancc
Fanconi anemia, complementation group C
chr24_+_34069675 0.09 ENSDART00000143995
si:ch211-190p8.2
si:ch211-190p8.2
chr18_+_5917625 0.09 ENSDART00000169100
glg1b
golgi glycoprotein 1b
chr3_-_40681001 0.09 ENSDART00000154929
si:dkey-33c3.1
si:dkey-33c3.1
chr1_+_27024068 0.09 ENSDART00000102322
bnc2
basonuclin 2
chr14_-_22495604 0.08 ENSDART00000137167
si:ch211-107m4.1
si:ch211-107m4.1
chr9_+_24920677 0.08 ENSDART00000037025
slc39a10
solute carrier family 39 (zinc transporter), member 10
chr9_-_10769097 0.07 ENSDART00000189967
tmbim1b
transmembrane BAX inhibitor motif containing 1b
chr25_+_32473277 0.07 ENSDART00000146451
sqor
sulfide quinone oxidoreductase
chr21_+_15704556 0.06 ENSDART00000024858
ENSDART00000146909
chchd10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr25_-_17494364 0.06 ENSDART00000154134
lrrc29
leucine rich repeat containing 29

Network of associatons between targets according to the STRING database.

First level regulatory network of gmeb2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0006522 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.5 1.6 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.5 2.3 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.4 1.4 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.3 0.8 GO:0043576 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.2 2.8 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.2 0.9 GO:0048103 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.2 0.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.2 0.6 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.2 0.5 GO:1903644 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.2 0.7 GO:0030091 protein repair(GO:0030091)
0.2 0.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.7 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.1 0.6 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.8 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.1 2.0 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.7 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 0.3 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.1 0.7 GO:0006013 mannose metabolic process(GO:0006013) GDP-mannose biosynthetic process(GO:0009298)
0.1 0.7 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.1 0.6 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 0.3 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.1 0.3 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.1 0.2 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.1 0.7 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.1 0.7 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.4 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.1 0.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.4 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.5 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.1 0.8 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.9 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.4 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.2 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.1 0.6 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.1 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 0.2 GO:0006168 adenine salvage(GO:0006168)
0.0 0.4 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.1 GO:0061400 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion(GO:0061400)
0.0 0.1 GO:0007567 parturition(GO:0007567) maternal process involved in parturition(GO:0060137)
0.0 0.8 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.9 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.2 GO:1904105 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.0 0.8 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.5 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 1.9 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031) pancreas morphogenesis(GO:0061113)
0.0 0.2 GO:0035627 ceramide transport(GO:0035627)
0.0 0.2 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.5 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.3 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.2 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.3 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.0 0.5 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.2 GO:0021794 thalamus development(GO:0021794)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0003160 endocardium morphogenesis(GO:0003160)
0.0 0.4 GO:0071218 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 0.4 GO:0009409 response to cold(GO:0009409)
0.0 0.3 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.6 GO:2000779 regulation of double-strand break repair(GO:2000779)
0.0 0.4 GO:0006298 mismatch repair(GO:0006298)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.4 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.4 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 1.2 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.2 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.4 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.2 GO:0006513 protein monoubiquitination(GO:0006513)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.2 0.8 GO:0017177 glucosidase II complex(GO:0017177)
0.2 0.5 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
0.2 1.6 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.2 0.5 GO:0072380 TRC complex(GO:0072380)
0.2 0.6 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.8 GO:0030891 VCB complex(GO:0030891)
0.1 1.1 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.7 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.1 0.6 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.8 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.6 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 0.4 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.5 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 0.4 GO:0035060 brahma complex(GO:0035060)
0.0 0.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 2.4 GO:0005657 replication fork(GO:0005657)
0.0 0.9 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.4 GO:0032300 mismatch repair complex(GO:0032300)
0.0 1.6 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0071546 pi-body(GO:0071546)
0.0 1.2 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.7 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 1.0 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 2.1 GO:0016607 nuclear speck(GO:0016607)
0.0 1.3 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0097546 ciliary base(GO:0097546)
0.0 0.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 1.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.1 GO:0000776 kinetochore(GO:0000776)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.8 2.3 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.5 2.4 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.5 1.4 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.2 0.6 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.2 0.8 GO:0008169 C-methyltransferase activity(GO:0008169)
0.2 0.7 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 1.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.5 GO:0005521 lamin binding(GO:0005521)
0.1 0.7 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.3 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.3 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.9 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.5 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.2 GO:0034246 core DNA-dependent RNA polymerase binding promoter specificity activity(GO:0000996) mitochondrial RNA polymerase binding promoter specificity activity(GO:0034246)
0.1 0.9 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 1.4 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 1.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.2 GO:0003999 adenine phosphoribosyltransferase activity(GO:0003999)
0.1 1.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.9 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.3 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0035620 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.0 0.1 GO:0004990 oxytocin receptor activity(GO:0004990)
0.0 0.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.6 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.3 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.8 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.3 GO:0019843 rRNA binding(GO:0019843)
0.0 0.5 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.3 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.5 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 2.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.3 PID IL5 PATHWAY IL5-mediated signaling events
0.1 0.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.9 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 2.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.7 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.8 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 0.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.7 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.1 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.6 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.6 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation