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PRJEB1986: zebrafish developmental stages transcriptome

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Results for gsc

Z-value: 1.48

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Transcription factors associated with gsc

Gene Symbol Gene ID Gene Info
gsc
ENSDARG00000059073 goosecoid
gsc
ENSDARG00000111184 goosecoid
gsc
ENSDARG00000115937 goosecoid

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gscdr11_v1_chr17_-_19344999_193449990.716.7e-04Click!

Activity profile of gsc motif

Sorted Z-values of gsc motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_54077740 14.28 ENSDART00000027000
rho
rhodopsin
chr17_-_51202339 8.70 ENSDART00000167117
si:ch1073-469d17.2
si:ch1073-469d17.2
chr14_+_32838110 7.37 ENSDART00000158077
arr3b
arrestin 3b, retinal (X-arrestin)
chr6_+_41186320 7.24 ENSDART00000025241
opn1mw2
opsin 1 (cone pigments), medium-wave-sensitive, 2
chr6_-_345503 6.48 ENSDART00000168901
pde6ha
phosphodiesterase 6H, cGMP-specific, cone, gamma, paralog a
chr11_-_15090118 6.25 ENSDART00000171118
slc1a8a
solute carrier family 1 (glutamate transporter), member 8a
chr3_-_32170850 6.15 ENSDART00000055307
ENSDART00000157366
tnnt1
troponin T type 1 (skeletal, slow)
chr11_-_15090564 5.55 ENSDART00000162079
slc1a8a
solute carrier family 1 (glutamate transporter), member 8a
chr14_+_32839535 5.22 ENSDART00000168975
arr3b
arrestin 3b, retinal (X-arrestin)
chr15_+_45640906 5.10 ENSDART00000149361
ENSDART00000149079
sagb
S-antigen; retina and pineal gland (arrestin) b
chr19_+_40856534 5.07 ENSDART00000051950
gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr14_+_32837914 5.05 ENSDART00000158888
arr3b
arrestin 3b, retinal (X-arrestin)
chr7_-_13882988 4.76 ENSDART00000169828
rlbp1a
retinaldehyde binding protein 1a
chr10_-_20453995 4.62 ENSDART00000168541
ENSDART00000164072
si:ch211-113d22.2
si:ch211-113d22.2
chr19_+_40856807 4.60 ENSDART00000139083
gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr14_+_46313396 4.46 ENSDART00000047525
cryba1l1
crystallin, beta A1, like 1
chr5_+_28973264 4.28 ENSDART00000005638
stxbp1b
syntaxin binding protein 1b
chr1_-_58009216 4.14 ENSDART00000143829
nxnl1
nucleoredoxin like 1
chr5_+_28972935 4.12 ENSDART00000193274
stxbp1b
syntaxin binding protein 1b
chr23_+_39854566 3.99 ENSDART00000190423
ENSDART00000164473
ENSDART00000161881
si:ch73-217b7.1
si:ch73-217b7.1
chr2_+_7192966 3.90 ENSDART00000142735
si:ch211-13f8.1
si:ch211-13f8.1
chr14_+_46313135 3.86 ENSDART00000172902
cryba1l1
crystallin, beta A1, like 1
chr22_+_34701848 3.83 ENSDART00000082066
atpv0e2
ATPase H+ transporting V0 subunit e2
chr5_-_38161033 3.54 ENSDART00000145907
gucy2d
guanylate cyclase 2D, retinal
chr6_+_48618512 3.49 ENSDART00000111190
FAM19A3
si:dkey-238f9.1
chr3_-_28828242 3.41 ENSDART00000151445
si:ch211-76l23.4
si:ch211-76l23.4
chr17_-_16965809 3.34 ENSDART00000153697
nrxn3a
neurexin 3a
chr14_-_36378494 3.12 ENSDART00000058503
gpm6aa
glycoprotein M6Aa
chr17_+_36627099 2.99 ENSDART00000154104
impg1b
interphotoreceptor matrix proteoglycan 1b
chr10_-_22845485 2.92 ENSDART00000079454
vamp2
vesicle-associated membrane protein 2
chr21_-_28235361 2.90 ENSDART00000164458
nrxn2a
neurexin 2a
chr13_+_29462249 2.87 ENSDART00000147903
lrit1a
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1a
chr7_+_56615554 2.77 ENSDART00000098430
dpep1
dipeptidase 1
chr2_-_5356686 2.75 ENSDART00000124290
MFN1
mitofusin 1
chr12_+_5530247 2.67 ENSDART00000114637
ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr10_-_22249444 2.64 ENSDART00000148831
fgf11b
fibroblast growth factor 11b
chr9_+_33357011 2.57 ENSDART00000088569
nyx
nyctalopin
chr23_+_6232895 2.57 ENSDART00000139795
syt2a
synaptotagmin IIa
chr2_-_4797512 2.56 ENSDART00000160765
tnk2b
tyrosine kinase, non-receptor, 2b
chr16_+_32059785 2.53 ENSDART00000134459
si:dkey-40m6.8
si:dkey-40m6.8
chr13_+_3954715 2.50 ENSDART00000182477
ENSDART00000192142
ENSDART00000190962
lrrc73
leucine rich repeat containing 73
chr8_+_23142946 2.50 ENSDART00000152933
si:ch211-196c10.13
si:ch211-196c10.13
chr3_+_34919810 2.50 ENSDART00000055264
ca10b
carbonic anhydrase Xb
chr13_+_3954540 2.50 ENSDART00000092646
lrrc73
leucine rich repeat containing 73
chr5_+_1278092 2.48 ENSDART00000147972
ENSDART00000159783
dnm1a
dynamin 1a
chr7_-_49594995 2.40 ENSDART00000174161
ENSDART00000109147
brsk2b
BR serine/threonine kinase 2b
chr15_+_9053059 2.40 ENSDART00000012039
ppm1na
protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative)
chr23_-_21797517 2.40 ENSDART00000110041
lrrc38a
leucine rich repeat containing 38a
chr13_+_12528043 2.38 ENSDART00000057761
rrh
retinal pigment epithelium-derived rhodopsin homolog
chr16_-_17188294 2.37 ENSDART00000165883
opn9
opsin 9
chr17_-_15149192 2.35 ENSDART00000180511
ENSDART00000103405
gch1
GTP cyclohydrolase 1
chr2_+_24199073 2.34 ENSDART00000144110
map4l
microtubule associated protein 4 like
chr2_-_30784198 2.34 ENSDART00000182523
ENSDART00000147355
rgs20
regulator of G protein signaling 20
chr22_+_5103349 2.34 ENSDART00000083474
atcaya
ataxia, cerebellar, Cayman type a
chr25_+_27923846 2.32 ENSDART00000047007
slc13a1
solute carrier family 13 member 1
chr19_+_1097393 2.28 ENSDART00000168218
CABZ01111953.1

chr1_+_41690402 2.22 ENSDART00000177298
fbxo41
F-box protein 41
chr19_-_10373630 2.21 ENSDART00000131517
si:ch211-232m10.6
si:ch211-232m10.6
chr9_+_13685921 2.18 ENSDART00000145775
mpp4a
membrane protein, palmitoylated 4a (MAGUK p55 subfamily member 4)
chr1_-_45920632 2.14 ENSDART00000140890
pnpla6
patatin-like phospholipase domain containing 6
chr24_-_6501211 2.14 ENSDART00000186241
ENSDART00000109040
ENSDART00000136154
gpr158a
G protein-coupled receptor 158a
chr11_-_44873780 2.10 ENSDART00000160465
opn6a
opsin 6, group member a
chr3_+_34220194 2.08 ENSDART00000145859
slc25a23b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23b
chr6_+_9867426 2.05 ENSDART00000151749
MPP4 (1 of many)
si:ch211-222n4.6
chr25_-_17552299 2.01 ENSDART00000154327
si:dkey-44k1.5
si:dkey-44k1.5
chr23_-_10137322 1.97 ENSDART00000142442
plxnb1a
plexin b1a
chr23_-_1587955 1.93 ENSDART00000136037
fndc7b
fibronectin type III domain containing 7b
chr7_-_66864756 1.87 ENSDART00000184462
ENSDART00000189424
ampd3a
adenosine monophosphate deaminase 3a
chr6_-_35401282 1.87 ENSDART00000127612
rgs5a
regulator of G protein signaling 5a
chr17_+_15845765 1.80 ENSDART00000130881
ENSDART00000074936
gabrr2a
gamma-aminobutyric acid (GABA) A receptor, rho 2a
chr17_-_20979077 1.75 ENSDART00000006676
phyhipla
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr3_-_49504023 1.72 ENSDART00000168108
prkacaa
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a
chr12_+_41991635 1.69 ENSDART00000186161
ENSDART00000192510
TCERG1L
transcription elongation regulator 1 like
chr20_+_29587995 1.67 ENSDART00000153339
adam17b
ADAM metallopeptidase domain 17b
chr25_+_192116 1.66 ENSDART00000153983
zgc:114188
zgc:114188
chr12_+_47044707 1.65 ENSDART00000186506
zranb1a
zinc finger, RAN-binding domain containing 1a
chr20_-_25436389 1.62 ENSDART00000153266
itsn2a
intersectin 2a
chr1_-_45177373 1.60 ENSDART00000143142
ENSDART00000034549
zgc:111983
zgc:111983
chr22_+_38164486 1.57 ENSDART00000137521
tm4sf18
transmembrane 4 L six family member 18
chr20_-_18736281 1.51 ENSDART00000142837
enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr17_-_33414781 1.49 ENSDART00000142203
ENSDART00000034638
ccdc28a
coiled-coil domain containing 28A
chr23_-_17509656 1.47 ENSDART00000148423
dnajc5ab
DnaJ (Hsp40) homolog, subfamily C, member 5ab
chr24_-_7777389 1.45 ENSDART00000138541
rpgrip1
RPGR interacting protein 1
chr1_-_7894255 1.45 ENSDART00000167126
ENSDART00000145460
radil
Ras association and DIL domains
chr20_-_14680897 1.43 ENSDART00000063857
ENSDART00000161314
scrn2
secernin 2
chr3_+_26144765 1.43 ENSDART00000146267
ENSDART00000043932
atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr2_+_28995776 1.43 ENSDART00000138733
cdh12a
cadherin 12, type 2a (N-cadherin 2)
chr24_-_24271629 1.40 ENSDART00000135060
rps6ka3b
ribosomal protein S6 kinase, polypeptide 3b
chr3_-_16227683 1.35 ENSDART00000111707
cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr4_-_14926637 1.35 ENSDART00000110199
prdm4
PR domain containing 4
chr3_+_14157090 1.34 ENSDART00000156766
si:ch211-108d22.2
si:ch211-108d22.2
chr11_-_28148033 1.32 ENSDART00000177182
lactbl1b
lactamase, beta-like 1b
chr6_-_59381391 1.30 ENSDART00000157066
ppp1r16b
protein phosphatase 1, regulatory subunit 16B
chr8_+_4337312 1.30 ENSDART00000182228
myl2b
myosin, light chain 2b, regulatory, cardiac, slow
chr7_-_57933736 1.30 ENSDART00000142580
ank2b
ankyrin 2b, neuronal
chr17_-_15657029 1.30 ENSDART00000153925
fut9a
fucosyltransferase 9a
chr22_-_910926 1.29 ENSDART00000180075
FP016205.1

chr24_-_38079261 1.28 ENSDART00000105662
crp1
C-reactive protein 1
chr15_+_15375607 1.27 ENSDART00000129751
si:ch211-105f12.2
si:ch211-105f12.2
chr10_+_22134606 1.26 ENSDART00000155228
si:dkey-4c2.11
si:dkey-4c2.11
chr2_-_1569250 1.25 ENSDART00000167202
dab1b
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr7_-_9674073 1.22 ENSDART00000187902
lrrk1
leucine-rich repeat kinase 1
chr18_-_36135799 1.21 ENSDART00000059344
b3gat1a
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a
chr10_+_6013076 1.18 ENSDART00000167613
ENSDART00000159216
hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr21_-_15046065 1.18 ENSDART00000178507
mmp17a
matrix metallopeptidase 17a
chr1_+_55758257 1.13 ENSDART00000139312
tecrb
trans-2,3-enoyl-CoA reductase b
chr18_-_1228688 1.13 ENSDART00000064403
nptnb
neuroplastin b
chr11_+_36180349 1.13 ENSDART00000012940
grm2b
glutamate receptor, metabotropic 2b
chr7_-_35516251 1.12 ENSDART00000045628
irx6a
iroquois homeobox 6a
chr2_+_30721070 1.08 ENSDART00000099052
si:dkey-94e7.2
si:dkey-94e7.2
chr22_+_38581012 1.06 ENSDART00000169239
BX088728.1

chr24_-_24060632 1.06 ENSDART00000090514
abcc13
ATP-binding cassette, sub-family C (CFTR/MRP), member 13
chr20_-_9963713 1.04 ENSDART00000104234
gjd2b
gap junction protein delta 2b
chr21_-_2348838 1.03 ENSDART00000160337
si:ch73-299h12.8
si:ch73-299h12.8
chr19_+_24068223 1.00 ENSDART00000141351
ENSDART00000100420
pex11b
peroxisomal biogenesis factor 11 beta
chr25_+_22274642 1.00 ENSDART00000127099
nr2e3
nuclear receptor subfamily 2, group E, member 3
chr9_-_29544720 1.00 ENSDART00000130317
arhgap20
Rho GTPase activating protein 20
chr18_-_43884044 1.00 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr10_-_36738619 0.99 ENSDART00000093000
ENSDART00000157179
PLEKHB1
si:ch211-176g13.7
chr2_-_52365251 0.98 ENSDART00000097716
tle2c
transducin like enhancer of split 2c
chr2_+_30878864 0.98 ENSDART00000009326
oprk1
opioid receptor, kappa 1
chr19_-_11846958 0.96 ENSDART00000148516
ctdp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr17_-_21368775 0.96 ENSDART00000058027
shtn1
shootin 1
chr21_-_39327223 0.95 ENSDART00000115097
aifm5
apoptosis-inducing factor, mitochondrion-associated, 5
chr4_-_7212875 0.94 ENSDART00000161297
lrrn3b
leucine rich repeat neuronal 3b
chr15_-_38154616 0.91 ENSDART00000099392
irgq2
immunity-related GTPase family, q2
chr16_-_22585289 0.87 ENSDART00000134239
ENSDART00000193959
ENSDART00000077998
si:dkey-238m4.3
cgna
si:dkey-238m4.3
cingulin a
chr12_+_7865470 0.86 ENSDART00000161683
BX548028.1

chr18_-_7948188 0.85 ENSDART00000091805
shank3a
SH3 and multiple ankyrin repeat domains 3a
chr5_+_24287927 0.85 ENSDART00000143563
zdhhc23a
zinc finger, DHHC-type containing 23a
chr3_-_33574576 0.77 ENSDART00000184881
CR847537.1

chr7_+_4384863 0.76 ENSDART00000042955
ENSDART00000134653
slc12a10.3
slc12a10.3 solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 3
chr7_-_35515931 0.75 ENSDART00000193324
irx6a
iroquois homeobox 6a
chr3_-_16227490 0.73 ENSDART00000057159
ENSDART00000130611
ENSDART00000012835
cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr21_-_20733615 0.72 ENSDART00000145544
si:ch211-22d5.2
si:ch211-22d5.2
chr1_-_7893808 0.70 ENSDART00000110154
radil
Ras association and DIL domains
chr19_+_4061699 0.69 ENSDART00000158309
ENSDART00000166512
btr25
btr26
bloodthirsty-related gene family, member 25
bloodthirsty-related gene family, member 26
chr16_+_29555801 0.68 ENSDART00000169425
ensab
endosulfine alpha b
chr19_-_32944050 0.67 ENSDART00000137611
azin1b
antizyme inhibitor 1b
chr4_-_760560 0.67 ENSDART00000103601
agbl5
ATP/GTP binding protein-like 5
chr3_-_30941362 0.60 ENSDART00000076830
coro1a
coronin, actin binding protein, 1A
chrM_+_12897 0.59 ENSDART00000093622
mt-nd5
NADH dehydrogenase 5, mitochondrial
chr6_-_19270484 0.59 ENSDART00000186894
ENSDART00000188709
zgc:174863
zgc:174863
chr13_-_36525982 0.58 ENSDART00000114744
pacs2
phosphofurin acidic cluster sorting protein 2
chr14_+_44545092 0.56 ENSDART00000175454
lingo2a
leucine rich repeat and Ig domain containing 2a
chr8_+_2656231 0.55 ENSDART00000160833
fam102aa
family with sequence similarity 102, member Aa
chr7_+_17063761 0.55 ENSDART00000182880
htatip2
HIV-1 Tat interactive protein 2
chr10_+_13279079 0.54 ENSDART00000135082
tmem267
transmembrane protein 267
chr20_+_37295006 0.50 ENSDART00000153137
cx23
connexin 23
chr7_-_12821277 0.50 ENSDART00000091584
zgc:158785
zgc:158785
chr25_+_19041329 0.45 ENSDART00000153467
lrtm2b
leucine-rich repeats and transmembrane domains 2b
chr2_-_16986894 0.44 ENSDART00000145720
clcn2a
chloride channel, voltage-sensitive 2a
chr17_-_14559576 0.42 ENSDART00000162452
daam1a
dishevelled associated activator of morphogenesis 1a
chr11_+_27973055 0.42 ENSDART00000135135
alpl
alkaline phosphatase, liver/bone/kidney
chr9_-_14084743 0.41 ENSDART00000056105
fer1l6
fer-1-like family member 6
chr2_-_9818640 0.38 ENSDART00000139499
ENSDART00000165548
ENSDART00000012442
ENSDART00000046587
ap2m1b
adaptor-related protein complex 2, mu 1 subunit, b
chr2_-_42071558 0.37 ENSDART00000142792
cspp1b
centrosome and spindle pole associated protein 1b
chr2_+_30531726 0.35 ENSDART00000146518
ankrd33bb
ankyrin repeat domain 33Bb
chr19_+_24882845 0.35 ENSDART00000010580
si:ch211-195b13.1
si:ch211-195b13.1
chr21_-_36948 0.34 ENSDART00000181230
JMY
junction mediating and regulatory protein, p53 cofactor
chr3_+_52475058 0.32 ENSDART00000035867
si:ch211-241f5.3
si:ch211-241f5.3
chr7_+_30970045 0.31 ENSDART00000155974
tjp1a
tight junction protein 1a
chr24_+_3478871 0.30 ENSDART00000111491
ENSDART00000134598
ENSDART00000142407
wdr37
WD repeat domain 37
chr1_+_16573982 0.28 ENSDART00000166317
mtus1b
microtubule associated tumor suppressor 1b
chr19_+_2275019 0.27 ENSDART00000136138
itgb8
integrin, beta 8
chr5_-_33274645 0.27 ENSDART00000188584
kyat1
kynurenine aminotransferase 1
chr17_-_50010121 0.26 ENSDART00000122747
tmem30aa
transmembrane protein 30Aa
chr3_-_10970502 0.25 ENSDART00000127500
CR382337.1

chr20_+_13533544 0.23 ENSDART00000143115
sytl3
synaptotagmin-like 3
chr5_-_57526807 0.21 ENSDART00000022866
pisd
phosphatidylserine decarboxylase
chr16_-_31675669 0.20 ENSDART00000168848
ENSDART00000158331
c1r
complement component 1, r subcomponent
chr16_+_11297703 0.19 ENSDART00000125158
znf574
zinc finger protein 574
chr22_-_20695237 0.17 ENSDART00000112722
org
oogenesis-related gene
chr24_-_1303553 0.17 ENSDART00000190984
nrp1a
neuropilin 1a
chr7_+_20031202 0.16 ENSDART00000052904
slc16a13
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr8_+_48848200 0.16 ENSDART00000130673
tp73
tumor protein p73
chr5_+_67371650 0.13 ENSDART00000142156
sebox
SEBOX homeobox
chr8_+_21280360 0.13 ENSDART00000144488
itpr3
inositol 1,4,5-trisphosphate receptor, type 3
chr5_+_8767290 0.12 ENSDART00000189377
CR854981.1

chr23_-_28294763 0.11 ENSDART00000139537
znf385a
zinc finger protein 385A
chr15_-_14486534 0.10 ENSDART00000179368
numbl
numb homolog (Drosophila)-like
chr21_-_35419486 0.10 ENSDART00000138529
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr3_-_58798815 0.09 ENSDART00000082920
si:ch73-281f12.4
si:ch73-281f12.4
chr25_-_22889519 0.09 ENSDART00000128250
mob2a
MOB kinase activator 2a
chr7_-_50517023 0.09 ENSDART00000073910
adamtsl5
ADAMTS like 5
chr7_-_18656069 0.08 ENSDART00000021559
coro1b
coronin, actin binding protein, 1B
chr11_-_3366782 0.08 ENSDART00000127982
suox
sulfite oxidase
chr20_+_32473584 0.08 ENSDART00000192449
ostm1
osteopetrosis associated transmembrane protein 1
chr22_+_661505 0.06 ENSDART00000149460
elf3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr4_+_33012407 0.06 ENSDART00000151873
si:dkey-26h11.2
si:dkey-26h11.2
chr24_+_5826005 0.04 ENSDART00000154930
si:ch211-157j23.5
si:ch211-157j23.5
chr17_-_32863250 0.04 ENSDART00000167292
prox1a
prospero homeobox 1a
chr1_+_27690 0.03 ENSDART00000162928
eed
embryonic ectoderm development
chr7_-_17780048 0.03 ENSDART00000183336
si:dkey-106g10.7
si:dkey-106g10.7
chr20_+_36629173 0.02 ENSDART00000161241
ephx1
epoxide hydrolase 1, microsomal (xenobiotic)
chr18_-_25646286 0.02 ENSDART00000099511
ENSDART00000186890
si:ch211-13k12.2
si:ch211-13k12.2

Network of associatons between targets according to the STRING database.

First level regulatory network of gsc

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 14.3 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
1.9 22.7 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
1.1 6.5 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.9 6.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.6 2.4 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.4 1.2 GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.4 1.4 GO:0031448 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.3 1.7 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.3 1.0 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.3 7.3 GO:0007634 optokinetic behavior(GO:0007634)
0.3 13.3 GO:0007602 phototransduction(GO:0007602)
0.3 1.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 1.7 GO:0071331 cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.2 1.0 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.2 2.3 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.2 2.9 GO:0035493 SNARE complex assembly(GO:0035493)
0.2 8.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.2 1.0 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.2 2.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 1.0 GO:0016559 peroxisome fission(GO:0016559)
0.2 5.1 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.2 1.3 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 0.6 GO:0015990 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.1 2.1 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 3.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.9 GO:0032264 IMP salvage(GO:0032264)
0.1 0.7 GO:0035608 protein deglutamylation(GO:0035608)
0.1 1.4 GO:0046548 retinal rod cell development(GO:0046548)
0.1 2.5 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 1.0 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.8 GO:2000463 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 2.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.7 GO:1902269 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 2.4 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 2.0 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 2.3 GO:0008272 sulfate transport(GO:0008272)
0.1 3.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 1.3 GO:0036065 fucosylation(GO:0036065)
0.1 0.6 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 1.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 1.7 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 2.5 GO:0036269 swimming behavior(GO:0036269)
0.1 10.6 GO:0007601 visual perception(GO:0007601)
0.1 2.1 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 1.6 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.1 3.8 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 1.2 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 1.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.1 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 1.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 1.2 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 3.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 2.6 GO:0007098 centrosome cycle(GO:0007098)
0.0 1.1 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 2.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 1.6 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.7 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.8 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 1.3 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 1.4 GO:0001503 ossification(GO:0001503)
0.0 5.1 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.0 0.4 GO:0006821 chloride transport(GO:0006821)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.9 13.6 GO:0060170 ciliary membrane(GO:0060170)
0.6 9.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.5 2.6 GO:0042584 chromaffin granule membrane(GO:0042584)
0.5 18.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.4 3.0 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.4 1.4 GO:0031673 H zone(GO:0031673)
0.3 4.1 GO:0044295 axonal growth cone(GO:0044295)
0.3 3.8 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.2 1.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 6.2 GO:0005861 troponin complex(GO:0005861)
0.1 2.5 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 1.0 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 8.5 GO:0030141 secretory granule(GO:0030141)
0.1 1.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 2.0 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 2.9 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.3 GO:0030315 T-tubule(GO:0030315)
0.1 1.0 GO:0005922 connexon complex(GO:0005922)
0.1 1.8 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 3.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 2.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 2.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 3.4 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.4 GO:0016342 catenin complex(GO:0016342)
0.0 2.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 2.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 14.3 GO:0005502 11-cis retinal binding(GO:0005502)
0.6 2.8 GO:0070573 metallodipeptidase activity(GO:0070573)
0.5 6.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.5 9.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.5 1.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.4 1.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.3 1.7 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.3 1.3 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.3 1.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3 13.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.3 1.4 GO:0070004 dipeptidase activity(GO:0016805) cysteine-type exopeptidase activity(GO:0070004)
0.3 11.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 5.6 GO:0005523 tropomyosin binding(GO:0005523)
0.2 3.9 GO:0005080 protein kinase C binding(GO:0005080)
0.2 2.3 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.2 1.3 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.2 1.0 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.2 3.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 2.4 GO:0019238 cyclohydrolase activity(GO:0019238)
0.2 1.9 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 1.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.2 2.0 GO:0005222 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 1.0 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.8 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 1.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.7 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 2.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 2.1 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 1.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 2.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 22.7 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.1 2.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 7.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 3.3 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 0.3 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.1 2.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.8 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 1.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 2.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 2.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 11.8 GO:0015293 symporter activity(GO:0015293)
0.1 2.4 GO:0030145 manganese ion binding(GO:0030145)
0.1 2.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 3.0 GO:0044325 ion channel binding(GO:0044325)
0.1 1.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 2.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 4.2 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 1.6 GO:0051020 GTPase binding(GO:0051020)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 3.8 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 3.4 GO:0008201 heparin binding(GO:0008201)
0.0 1.1 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.0 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.1 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 1.4 GO:0045296 cadherin binding(GO:0045296)
0.0 2.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 26.9 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.3 2.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 2.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.4 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 23.9 REACTOME OPSINS Genes involved in Opsins
2.4 9.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
1.0 2.9 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.3 2.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 6.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 2.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.0 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 1.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.4 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 1.0 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events