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PRJEB1986: zebrafish developmental stages transcriptome

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Results for hbp1

Z-value: 0.45

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Transcription factors associated with hbp1

Gene Symbol Gene ID Gene Info
ENSDARG00000028517 HMG-box transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hbp1dr11_v1_chr25_-_3469576_34695760.417.8e-02Click!

Activity profile of hbp1 motif

Sorted Z-values of hbp1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_13792490 2.59 ENSDART00000136754
cadherin 13, H-cadherin (heart)
chr24_-_6898302 1.99 ENSDART00000158646
dipeptidyl-peptidase 6a
chr15_+_45643787 1.60 ENSDART00000055995
ENSDART00000157750
S-antigen; retina and pineal gland (arrestin) b
chr12_-_11457625 1.47 ENSDART00000012318
HtrA serine peptidase 1b
chr23_+_10352921 1.21 ENSDART00000081193
si:ch211-133j6.3
chr1_-_59252973 1.13 ENSDART00000167061
si:ch1073-286c18.5
chr1_-_14258409 1.00 ENSDART00000079359
phosphodiesterase 5A, cGMP-specific, a
chr7_-_66868543 0.94 ENSDART00000149680
adenosine monophosphate deaminase 3a
chr14_+_6159162 0.93 ENSDART00000128638
Bernardinelli-Seip congenital lipodystrophy 2, like
chr25_+_7229046 0.92 ENSDART00000149965
ENSDART00000041820
leucine rich repeat and Ig domain containing 1a
chr11_-_7355995 0.84 ENSDART00000156595
si:dkey-197i20.6
chr22_+_35068046 0.78 ENSDART00000161660
ENSDART00000169573
si:ch73-173h19.3
chr14_-_2196267 0.76 ENSDART00000161674
ENSDART00000125674
protocadherin 2 alpha b 8
protocadherin 2 alpha b 9
chr3_+_35298078 0.72 ENSDART00000110126
calcium channel, voltage-dependent, gamma subunit 3b
chr14_-_46238186 0.71 ENSDART00000173245
si:ch211-113d11.6
chr8_+_48613040 0.69 ENSDART00000121432
natriuretic peptide A
chr14_+_6159356 0.68 ENSDART00000157730
Bernardinelli-Seip congenital lipodystrophy 2, like
chr14_-_2199573 0.68 ENSDART00000124485
protocadherin 2 alpha b 8
chr21_+_45626136 0.66 ENSDART00000158742
interferon regulatory factor 1b
chr22_-_26865181 0.64 ENSDART00000138311
heme oxygenase 2a
chr13_+_45709380 0.63 ENSDART00000192862
si:ch211-62a1.3
chr13_-_22843562 0.61 ENSDART00000142738
phenazine biosynthesis like protein domain containing
chr22_-_25033105 0.59 ENSDART00000124220
neuronal pentraxin receptor b
chr6_-_40722200 0.58 ENSDART00000035101
kelch repeat and BTB (POZ) domain containing 12
chr17_-_26537928 0.57 ENSDART00000155692
ENSDART00000122366
coiled-coil serine-rich protein 2a
chr17_+_15297398 0.55 ENSDART00000156574
si:ch211-270g19.5
chr18_+_45573251 0.54 ENSDART00000191309
kinesin family member C3
chr25_-_35182347 0.54 ENSDART00000115210
anoctamin 9a
chr23_-_24343363 0.54 ENSDART00000166392
family with sequence similarity 131, member C
chr6_-_24103666 0.50 ENSDART00000164915
scinderin like a
chr15_-_28107502 0.50 ENSDART00000152270
ENSDART00000167129
crystallin, beta A1a
chr20_+_1088658 0.50 ENSDART00000162991

chr6_+_23887314 0.50 ENSDART00000163188
zinc finger protein 648
chr15_-_15357178 0.49 ENSDART00000106120
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2
chr5_+_9434288 0.47 ENSDART00000162089
UDP glucuronosyltransferase 2 family, polypeptide A7
chr3_-_30609659 0.47 ENSDART00000182516
ENSDART00000187047
ENSDART00000110597
synaptotagmin III
chr19_-_27196090 0.45 ENSDART00000045616
gamma-aminobutyric acid (GABA) B receptor, 1b
chr15_-_27972474 0.45 ENSDART00000162753

chr3_-_4303262 0.44 ENSDART00000112819
si:dkey-73p2.2
chr1_+_10221568 0.42 ENSDART00000152424
neuropeptide Y receptor Y2, like
chr3_+_4346854 0.39 ENSDART00000004273
si:dkey-73p2.3
chr3_-_36612877 0.39 ENSDART00000167164
si:dkeyp-72e1.7
chr8_+_22582146 0.39 ENSDART00000157655
ENSDART00000189892

chr11_+_36243774 0.37 ENSDART00000023323
zgc:172270
chr19_-_32487469 0.37 ENSDART00000050130
guanosine monophosphate reductase
chr25_-_31698550 0.36 ENSDART00000058400
laminin, beta 4
chr10_-_15405564 0.35 ENSDART00000020665
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr3_-_23407720 0.34 ENSDART00000155658
Rap guanine nucleotide exchange factor (GEF)-like 1
chr21_-_7035599 0.33 ENSDART00000139777
si:ch211-93g21.1
chr16_-_52916248 0.33 ENSDART00000113931
zinc finger, DHHC-type containing 11
chr11_+_24877820 0.32 ENSDART00000006038
shisa family member 4
chr5_-_28149767 0.32 ENSDART00000051515
zgc:110329
chr7_+_27691647 0.32 ENSDART00000079091
cytochrome P450, family 2, subfamily R, polypeptide 1
chr13_+_18202703 0.31 ENSDART00000109642
tet methylcytosine dioxygenase 1
chr17_+_21514777 0.30 ENSDART00000154633
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr16_-_41439659 0.30 ENSDART00000191624
copine IVa
chr12_-_3453589 0.29 ENSDART00000175918

chr20_-_44496245 0.29 ENSDART00000012229
FK506 binding protein 1b
chr5_-_2721686 0.28 ENSDART00000169404
heat shock protein 5
chr16_+_46453176 0.27 ENSDART00000132793
rapunzel 3
chr23_+_2760573 0.27 ENSDART00000129719
DNA topoisomerase I
chr16_-_51299061 0.27 ENSDART00000148677
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 4
chr2_+_9061885 0.25 ENSDART00000028906
phosphatidylinositol glycan anchor biosynthesis, class K
chr24_+_4373033 0.22 ENSDART00000133360
cyclin Y
chr5_+_20437124 0.22 ENSDART00000159001
transmembrane protein 119a
chr22_+_7923713 0.22 ENSDART00000167210

chr18_-_19103929 0.21 ENSDART00000188370
ENSDART00000177621
DENN/MADD domain containing 4A
chr1_-_47071979 0.21 ENSDART00000160817
intersectin 1 (SH3 domain protein)
chr21_-_35325466 0.21 ENSDART00000134780
ENSDART00000145930
ENSDART00000076715
ENSDART00000065341
ENSDART00000162189
ubiquitin-like domain containing CTD phosphatase 1
chr17_+_37253706 0.20 ENSDART00000076004
transmembrane protein 62
chr1_-_45341760 0.20 ENSDART00000149183
ENSDART00000148289
ENSDART00000110390
zgc:101679
chr3_+_11101585 0.19 ENSDART00000172103
somatostatin receptor 5
chr23_+_23182037 0.19 ENSDART00000137353
kelch-like family member 17
chr9_+_30577925 0.19 ENSDART00000139811
COMM domain containing 6
chr3_-_23406964 0.19 ENSDART00000114723
Rap guanine nucleotide exchange factor (GEF)-like 1
chr1_-_33380011 0.19 ENSDART00000141347
ENSDART00000136383
CD99 molecule
chr11_+_30058139 0.18 ENSDART00000112254
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr1_+_6206950 0.18 ENSDART00000146473
reticulophagy regulator family member 2
chr12_+_2381213 0.17 ENSDART00000188007

chr15_+_31816835 0.17 ENSDART00000189658
ENSDART00000186634
ENSDART00000193032
ENSDART00000180401
furry homolog a (Drosophila)
chr4_+_56379907 0.17 ENSDART00000169142
si:dkey-41c6.3
chr17_-_26911852 0.16 ENSDART00000045842
regulator of calcineurin 3
chr4_-_72468168 0.16 ENSDART00000182995
ENSDART00000174067

chr20_-_46773258 0.16 ENSDART00000060653
si:ch211-57i17.5
chr1_+_7414318 0.15 ENSDART00000127426
si:ch73-383l1.1
chr21_-_22648007 0.15 ENSDART00000121788
grass carp reovirus (GCRV)-induced gene 2l
chr22_-_7778895 0.14 ENSDART00000125489
si:ch73-44m9.3
chr1_-_44901163 0.14 ENSDART00000145354
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3a
chr23_-_32092443 0.13 ENSDART00000133688
LETM1 domain containing 1
chr18_+_17611627 0.13 ENSDART00000046891
cholesteryl ester transfer protein, plasma
chr23_+_5490854 0.13 ENSDART00000175403
tubby like protein 1a
chr7_-_20836625 0.13 ENSDART00000192566
claudin 15a
chr10_-_34916208 0.13 ENSDART00000187371
cyclin A1
chr4_-_76027176 0.12 ENSDART00000165718
si:dkey-71l4.1
chr15_-_19051152 0.12 ENSDART00000186453
Rho GTPase activating protein 32a
chr15_+_1199407 0.12 ENSDART00000163827
major facilitator superfamily domain containing 1
chr5_-_50600512 0.11 ENSDART00000190318
multiple C2 domains, transmembrane 1a
chr14_-_30945515 0.11 ENSDART00000161540
si:zfos-80g12.1
chr12_+_5215795 0.11 ENSDART00000170270
si:ch211-197g18.2
chr12_-_48970299 0.11 ENSDART00000163734
retinal G protein coupled receptor b
chr17_-_27419499 0.11 ENSDART00000186773
YTH N(6)-methyladenosine RNA binding protein 2
chr15_+_32297441 0.10 ENSDART00000153657
tripartite motif containing 3a
chr22_-_7778265 0.10 ENSDART00000097276
si:ch73-44m9.3
chr14_+_918287 0.09 ENSDART00000167066

chr25_-_7650335 0.09 ENSDART00000089034
myosin VAb
chr20_-_27086143 0.09 ENSDART00000008590
inositol-tetrakisphosphate 1-kinase a
chr1_-_633356 0.09 ENSDART00000171019
amyloid beta (A4) precursor protein a
chr16_+_7242610 0.09 ENSDART00000081477
sorcin
chr23_-_11128601 0.09 ENSDART00000131232
contactin 3a, tandem duplicate 2
chr13_+_14006118 0.09 ENSDART00000131875
ENSDART00000089528
attractin
chr5_+_20112032 0.08 ENSDART00000130554
ISG15 ubiquitin-like modifier
chr23_-_37291793 0.08 ENSDART00000083281
ENSDART00000187108
mitochondrial E3 ubiquitin protein ligase 1b
chr21_-_2209012 0.08 ENSDART00000158345
zgc:162971
chr23_-_45111637 0.08 ENSDART00000179776
si:ch73-168d20.1
chr18_+_50669456 0.07 ENSDART00000163005
si:dkey-151j17.4
chr12_+_47698356 0.07 ENSDART00000112010
leucine zipper, putative tumor suppressor 2b
chr13_-_31389661 0.07 ENSDART00000134630
zinc finger, DHHC-type containing 16a
chr15_-_23793641 0.07 ENSDART00000122891
transmembrane protein 97
chr17_+_18810904 0.06 ENSDART00000130899
si:dkey-288a3.2
chr23_+_27740592 0.05 ENSDART00000137875
desert hedgehog
chr12_+_38770654 0.05 ENSDART00000155367
kinesin family member 19
chr4_-_73190246 0.04 ENSDART00000170842

chr4_-_75505048 0.04 ENSDART00000163665
si:dkey-71l4.5
chr22_+_3238474 0.04 ENSDART00000157954
si:ch1073-178p5.3
chr6_+_29402997 0.04 ENSDART00000104298
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 5
chr4_-_76205022 0.04 ENSDART00000159687
ENSDART00000187593
si:ch211-106j21.5
chr7_-_4461104 0.03 ENSDART00000023090
ENSDART00000140770
solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 1
chr14_-_34512859 0.03 ENSDART00000140368
si:ch211-232m8.3
chr4_-_68868229 0.03 ENSDART00000159219
si:dkey-264f17.5
chr21_+_6034783 0.02 ENSDART00000169613
solute carrier family 4 (sodium bicarbonate cotransporter), member 4b
chr4_+_77920666 0.02 ENSDART00000129523
tubulin tyrosine ligase-like family, member 1
chr5_+_12888816 0.02 ENSDART00000139632
galactose-3-O-sulfotransferase 1a
chr23_-_31645760 0.01 ENSDART00000035031
serum/glucocorticoid regulated kinase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of hbp1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.6 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.2 0.7 GO:1905072 cardiac jelly development(GO:1905072)
0.2 1.6 GO:0034389 lipid particle organization(GO:0034389)
0.1 1.6 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 0.3 GO:1903332 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.1 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.6 GO:0006788 heme oxidation(GO:0006788)
0.1 0.2 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.1 0.9 GO:0032264 IMP salvage(GO:0032264)
0.1 2.0 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.1 0.3 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.1 0.7 GO:0050688 regulation of defense response to virus(GO:0050688)
0.1 0.5 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.1 0.3 GO:0070640 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.0 0.2 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.0 0.7 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.5 GO:0043462 regulation of ATPase activity(GO:0043462)
0.0 0.1 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.9 GO:0031103 axon regeneration(GO:0031103)
0.0 0.3 GO:0042026 protein refolding(GO:0042026)
0.0 0.4 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.1 GO:1901031 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 0.1 GO:2000391 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.8 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.4 GO:0051014 actin filament severing(GO:0051014)
0.0 0.4 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.1 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 0.2 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.3 GO:0019319 hexose biosynthetic process(GO:0019319) monosaccharide biosynthetic process(GO:0046364)
0.0 0.1 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.3 GO:0072380 TRC complex(GO:0072380)
0.1 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 0.4 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 2.6 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 2.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.4 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.4 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 2.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.0 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 1.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0047325 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 2.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.4 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0051117 ATPase binding(GO:0051117)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 PID AP1 PATHWAY AP-1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport