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PRJEB1986: zebrafish developmental stages transcriptome

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Results for hey2_hey1+heyl

Z-value: 1.14

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Transcription factors associated with hey2_hey1+heyl

Gene Symbol Gene ID Gene Info
hey2
ENSDARG00000013441 hes-related family bHLH transcription factor with YRPW motif 2
heyl
ENSDARG00000055798 hes related family bHLH transcription factor with YRPW motif like
hey1
ENSDARG00000070538 hes-related family bHLH transcription factor with YRPW motif 1
heyl
ENSDARG00000112770 hes related family bHLH transcription factor with YRPW motif like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hey2dr11_v1_chr20_-_39596338_39596338-0.888.8e-07Click!
hey1dr11_v1_chr19_-_31802296_31802296-0.541.7e-02Click!
heyldr11_v1_chr19_+_32553874_32553874-0.106.8e-01Click!

Activity profile of hey2_hey1+heyl motif

Sorted Z-values of hey2_hey1+heyl motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_13580348 8.33 ENSDART00000067160
opn1sw1
opsin 1 (cone pigments), short-wave-sensitive 1
chr3_+_23488652 6.39 ENSDART00000126282
nr1d1
nuclear receptor subfamily 1, group d, member 1
chr1_-_54765262 5.77 ENSDART00000150362
si:ch211-197k17.3
si:ch211-197k17.3
chr8_-_21372446 5.68 ENSDART00000061481
ENSDART00000079293
ela2l
elastase 2 like
chr8_-_25247284 4.34 ENSDART00000132697
gnat2
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr17_+_25414033 3.97 ENSDART00000001691
tdh2
L-threonine dehydrogenase 2
chr13_-_293250 3.94 ENSDART00000138581
chs1
chitin synthase 1
chr14_+_35748385 3.92 ENSDART00000064617
ENSDART00000074671
ENSDART00000172803
gria2b
glutamate receptor, ionotropic, AMPA 2b
chr2_+_21090317 3.90 ENSDART00000109568
ENSDART00000139633
pip4k2ab
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha b
chr14_+_35748206 3.63 ENSDART00000177391
gria2b
glutamate receptor, ionotropic, AMPA 2b
chr3_+_1015867 3.42 ENSDART00000109912
si:ch1073-464p5.5
si:ch1073-464p5.5
chr11_-_3552067 3.35 ENSDART00000163656
CAMK2N1
si:dkey-33m11.6
chr7_-_73752955 3.34 ENSDART00000171254
ENSDART00000009888
casq1b
calsequestrin 1b
chr10_+_17026870 3.30 ENSDART00000184529
ENSDART00000157480
CR855996.2

chr13_+_46803979 3.17 ENSDART00000159260
CU695232.1

chr21_-_42100471 3.08 ENSDART00000166148
gabra1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr18_-_40684756 3.05 ENSDART00000113799
ENSDART00000139042
si:ch211-132b12.7
si:ch211-132b12.7
chr14_+_46313135 3.04 ENSDART00000172902
cryba1l1
crystallin, beta A1, like 1
chr23_-_24856025 3.00 ENSDART00000142171
syt6a
synaptotagmin VIa
chr14_+_41409697 2.94 ENSDART00000173335
bcorl1
BCL6 corepressor-like 1
chr8_-_18239494 2.90 ENSDART00000079989
ENSDART00000022959
guk1b
guanylate kinase 1b
chr6_-_38818582 2.88 ENSDART00000149833
cnga3a
cyclic nucleotide gated channel alpha 3a
chr20_+_35473288 2.86 ENSDART00000047195
mep1a.1
meprin A, alpha (PABA peptide hydrolase), tandem duplicate 1
chr16_-_45069882 2.86 ENSDART00000058384
gapdhs
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr21_-_41588129 2.81 ENSDART00000164125
crebrf
creb3 regulatory factor
chr8_-_23081511 2.79 ENSDART00000142015
ENSDART00000135764
ENSDART00000147021
si:dkey-70p6.1
si:dkey-70p6.1
chr7_+_38717624 2.77 ENSDART00000132522
syt13
synaptotagmin XIII
chr10_+_158590 2.77 ENSDART00000081982
KCNJ15
potassium voltage-gated channel subfamily J member 15
chr21_+_6290566 2.62 ENSDART00000161647
fnbp1b
formin binding protein 1b
chr6_-_60147517 2.54 ENSDART00000083453
slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr18_+_10784730 2.50 ENSDART00000028938
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr19_+_43563179 2.49 ENSDART00000151478
cd164l2
CD164 sialomucin-like 2
chr18_-_21218851 2.45 ENSDART00000060160
calb2a
calbindin 2a
chr15_+_1148074 2.45 ENSDART00000152638
ENSDART00000152466
ENSDART00000188011
mlf1
myeloid leukemia factor 1
chr20_+_50115335 2.42 ENSDART00000031139
slc24a4b
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4b
chr1_-_50859053 2.41 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr7_-_823304 2.39 ENSDART00000173694
si:cabz01076231.1
si:cabz01076231.1
chr17_-_37195163 2.24 ENSDART00000108514
asxl2
additional sex combs like transcriptional regulator 2
chr24_+_39135419 2.22 ENSDART00000180941
tbc1d24
TBC1 domain family, member 24
chr10_-_41450367 2.20 ENSDART00000122682
ENSDART00000189549
cabp1b
calcium binding protein 1b
chr9_-_22281854 2.19 ENSDART00000146319
crygm2d3
crystallin, gamma M2d3
chr23_+_40452157 2.13 ENSDART00000113106
ENSDART00000140136
soga3b
SOGA family member 3b
chr11_+_45299447 2.13 ENSDART00000172999
mafgb
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb
chr15_+_16897554 2.11 ENSDART00000154679
ypel2b
yippee-like 2b
chr9_+_42066030 2.05 ENSDART00000185311
ENSDART00000015267
pcbp3
poly(rC) binding protein 3
chr21_+_31150438 2.03 ENSDART00000065366
st6gal1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr19_+_42469058 2.02 ENSDART00000076915
si:dkey-166k12.1
si:dkey-166k12.1
chr25_+_37443194 2.00 ENSDART00000163178
ENSDART00000190262
slc10a3
solute carrier family 10, member 3
chr5_-_26950374 1.99 ENSDART00000050542
htra4
HtrA serine peptidase 4
chr11_+_29770966 1.97 ENSDART00000088624
ENSDART00000124471
rpgrb
retinitis pigmentosa GTPase regulator b
chr5_+_26075230 1.97 ENSDART00000098473
klf9
Kruppel-like factor 9
chr21_+_31150773 1.96 ENSDART00000126205
st6gal1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr19_-_8940068 1.94 ENSDART00000043507
ciarta
circadian associated repressor of transcription a
chr17_-_37195354 1.93 ENSDART00000190963
asxl2
additional sex combs like transcriptional regulator 2
chr9_-_22240052 1.92 ENSDART00000111109
crygm2d9
crystallin, gamma M2d9
chr5_-_69314495 1.90 ENSDART00000182335
smtnb
smoothelin b
chr25_+_3328487 1.90 ENSDART00000181143
ldhbb
lactate dehydrogenase Bb
chr20_-_27733683 1.89 ENSDART00000103317
ENSDART00000138139
zgc:153157
zgc:153157
chr22_-_12160283 1.87 ENSDART00000146785
ENSDART00000128176
tmem163b
transmembrane protein 163b
chr12_+_24342303 1.86 ENSDART00000111239
nrxn1a
neurexin 1a
chr20_+_34915945 1.84 ENSDART00000153064
snap25a
synaptosomal-associated protein, 25a
chr1_+_9004719 1.84 ENSDART00000006211
ENSDART00000137211
prkcba
protein kinase C, beta a
chr3_+_32526263 1.84 ENSDART00000150897
si:ch73-367p23.2
si:ch73-367p23.2
chr9_-_22232902 1.83 ENSDART00000101845
crygm2d5
crystallin, gamma M2d5
chr21_+_11969603 1.82 ENSDART00000142247
ENSDART00000140652
mlnl
motilin-like
chr4_+_5180650 1.81 ENSDART00000067390
fgf6b
fibroblast growth factor 6b
chr17_+_43843536 1.80 ENSDART00000164097
FO704777.1

chr19_+_22850657 1.79 ENSDART00000130472
pkhd1l1
polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1
chr11_-_3959889 1.76 ENSDART00000159683
pbrm1
polybromo 1
chr18_+_6479963 1.75 ENSDART00000092752
ENSDART00000136333
wash1
WAS protein family homolog 1
chr8_-_42238543 1.72 ENSDART00000062697
gfra2a
GDNF family receptor alpha 2a
chr25_+_33192796 1.70 ENSDART00000125892
ENSDART00000121680
ENSDART00000014851
TPM1 (1 of many)
zgc:171719
chr6_-_44711942 1.70 ENSDART00000055035
cntn3b
contactin 3b
chr14_+_2095394 1.64 ENSDART00000186847
CT573264.2

chr3_+_32526799 1.63 ENSDART00000185755
si:ch73-367p23.2
si:ch73-367p23.2
chr21_+_6780340 1.63 ENSDART00000139493
ENSDART00000140478
olfm1b
olfactomedin 1b
chr3_+_1223824 1.63 ENSDART00000065922
wbp2nl
WBP2 N-terminal like
chr5_-_18897482 1.61 ENSDART00000010101
ENSDART00000099434
aacs
acetoacetyl-CoA synthetase
chr2_+_20331445 1.59 ENSDART00000186880
plppr4a
phospholipid phosphatase related 4a
chr25_+_37268900 1.59 ENSDART00000156737
si:dkey-234i14.6
si:dkey-234i14.6
chr6_+_22597362 1.59 ENSDART00000131242
cygb2
cytoglobin 2
chr15_-_44077937 1.58 ENSDART00000110112
lamtor1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr25_-_21092222 1.56 ENSDART00000154765
prr5a
proline rich 5a (renal)
chr21_+_6291027 1.53 ENSDART00000180467
ENSDART00000184952
ENSDART00000184006
fnbp1b
formin binding protein 1b
chr20_-_116999 1.51 ENSDART00000149581
ypel5
yippee-like 5
chr19_+_7152966 1.49 ENSDART00000080348
brd2a
bromodomain containing 2a
chr19_+_42470396 1.46 ENSDART00000191679
si:dkey-166k12.1
si:dkey-166k12.1
chr2_+_54696042 1.46 ENSDART00000074270
ankrd12
ankyrin repeat domain 12
chr18_-_226800 1.45 ENSDART00000165180
tarsl2
threonyl-tRNA synthetase-like 2
chr3_-_10425313 1.45 ENSDART00000111833
pctp
phosphatidylcholine transfer protein
chr8_+_25247245 1.45 ENSDART00000045798
ampd2b
adenosine monophosphate deaminase 2b
chr9_-_3149896 1.45 ENSDART00000020861
pdk1
pyruvate dehydrogenase kinase, isozyme 1
chr7_-_823495 1.42 ENSDART00000189926
ENSDART00000192318
si:cabz01076231.1
si:cabz01076231.1
chr24_-_38644937 1.42 ENSDART00000170194
slc6a16b
solute carrier family 6, member 16b
chr20_-_2949028 1.41 ENSDART00000104667
ENSDART00000193151
ENSDART00000131946
cdk19
cyclin-dependent kinase 19
chr11_-_37411492 1.41 ENSDART00000166468
erc2
ELKS/RAB6-interacting/CAST family member 2
chr25_-_35113891 1.40 ENSDART00000190724
zgc:165555
zgc:165555
chr13_-_25284716 1.40 ENSDART00000039828
vcla
vinculin a
chr13_-_37519774 1.39 ENSDART00000141420
ENSDART00000185478
sgpp1
sphingosine-1-phosphate phosphatase 1
chr13_-_3516473 1.36 ENSDART00000146240
prkn
parkin RBR E3 ubiquitin protein ligase
chr3_-_62380146 1.34 ENSDART00000155853
gprc5ba
G protein-coupled receptor, class C, group 5, member Ba
chr7_-_30082931 1.32 ENSDART00000075600
tspan3b
tetraspanin 3b
chr11_-_3959477 1.30 ENSDART00000045971
pbrm1
polybromo 1
chr2_+_6181383 1.30 ENSDART00000153307
si:ch73-344o19.1
si:ch73-344o19.1
chr10_+_10677697 1.29 ENSDART00000188705
fam163b
family with sequence similarity 163, member B
chr6_+_39184236 1.29 ENSDART00000156187
tac3b
tachykinin 3b
chr5_-_38342992 1.29 ENSDART00000140337
mink1
misshapen-like kinase 1
chr10_-_16028082 1.25 ENSDART00000122540
aldh7a1
aldehyde dehydrogenase 7 family, member A1
chr23_+_22819971 1.25 ENSDART00000111345
rerea
arginine-glutamic acid dipeptide (RE) repeats a
chr21_-_20765338 1.24 ENSDART00000135940
ghrb
growth hormone receptor b
chr9_-_35557397 1.20 ENSDART00000100681
ncam2
neural cell adhesion molecule 2
chr1_-_9231952 1.18 ENSDART00000166515
si:dkeyp-57d7.4
si:dkeyp-57d7.4
chr11_+_41135055 1.18 ENSDART00000173252
camta1
calmodulin binding transcription activator 1
chr2_-_5505094 1.18 ENSDART00000145035
saga
S-antigen; retina and pineal gland (arrestin) a
chr7_+_48999723 1.16 ENSDART00000182699
ENSDART00000166329
si:ch211-288d18.1
si:ch211-288d18.1
chr7_+_9922607 1.16 ENSDART00000184532
ENSDART00000113396
cers3a
ceramide synthase 3a
chr19_+_31183495 1.16 ENSDART00000088618
meox2b
mesenchyme homeobox 2b
chr19_+_33732188 1.16 ENSDART00000151192
runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr18_-_11729 1.15 ENSDART00000159781
WHAMM
WAS protein homolog associated with actin, golgi membranes and microtubules
chr19_-_205104 1.15 ENSDART00000011890
zbtb22a
zinc finger and BTB domain containing 22a
chr16_-_31622777 1.15 ENSDART00000137311
ENSDART00000002930
phf20l1
PHD finger protein 20 like 1
chr21_-_36948 1.14 ENSDART00000181230
JMY
junction mediating and regulatory protein, p53 cofactor
chr9_+_10014817 1.13 ENSDART00000132065
nxph2a
neurexophilin 2a
chr5_-_1999417 1.12 ENSDART00000155437
ENSDART00000145781
si:ch211-160e1.5
si:ch211-160e1.5
chr25_+_25123385 1.11 ENSDART00000163892
ldha
lactate dehydrogenase A4
chr18_-_9046805 1.10 ENSDART00000134224
grm3
glutamate receptor, metabotropic 3
chr10_+_21559605 1.08 ENSDART00000123648
ENSDART00000108584
pcdh1a3
pcdh1a3
protocadherin 1 alpha 3
protocadherin 1 alpha 3
chr20_+_19212962 1.08 ENSDART00000063706
fndc4a
fibronectin type III domain containing 4a
chr24_-_22702017 1.08 ENSDART00000179403
ctnnd2a
catenin (cadherin-associated protein), delta 2a
chr23_+_42131509 1.07 ENSDART00000184544
SHISAL2A
shisa like 2A
chr25_-_13871118 1.07 ENSDART00000160866
cry2
cryptochrome circadian clock 2
chr19_-_5103313 1.07 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr12_-_15620090 1.07 ENSDART00000038032
acbd4
acyl-CoA binding domain containing 4
chr20_-_14665002 1.06 ENSDART00000152816
scrn2
secernin 2
chr18_+_660578 1.06 ENSDART00000161203
CELF6
si:dkey-205h23.2
chr19_+_42142381 1.06 ENSDART00000129915
kcnq4
potassium voltage-gated channel, KQT-like subfamily, member 4
chr16_-_3127749 1.06 ENSDART00000063986
csf3r
colony stimulating factor 3 receptor (granulocyte)
chr11_-_43948885 1.03 ENSDART00000164522
CABZ01074203.1

chr18_-_19103929 1.03 ENSDART00000188370
ENSDART00000177621
dennd4a
DENN/MADD domain containing 4A
chr2_-_9489611 1.03 ENSDART00000146715
st6galnac3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr12_+_30586599 1.00 ENSDART00000124920
ENSDART00000126984
nrap
nebulin-related anchoring protein
chr23_+_39089574 0.98 ENSDART00000164711
nfatc2a
nuclear factor of activated T cells 2a
chr9_+_10014514 0.97 ENSDART00000185590
nxph2a
neurexophilin 2a
chr5_-_33935396 0.97 ENSDART00000133578
si:dkeyp-72a4.1
si:dkeyp-72a4.1
chr3_-_28120092 0.96 ENSDART00000151143
rbfox1
RNA binding fox-1 homolog 1
chr18_+_19990412 0.96 ENSDART00000155054
ENSDART00000090310
pias1b
protein inhibitor of activated STAT, 1b
chr1_+_7956030 0.95 ENSDART00000159655
CR855320.1

chr24_-_38787457 0.95 ENSDART00000112318
ENSDART00000154461
ntn2
netrin 2
chr10_+_575929 0.93 ENSDART00000129856
smad4a
SMAD family member 4a
chr6_-_24087279 0.91 ENSDART00000163445
zgc:109982
zgc:109982
chr12_-_33359654 0.91 ENSDART00000001907
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr21_+_1378250 0.91 ENSDART00000186912
TCF4
transcription factor 4
chr11_-_37880492 0.90 ENSDART00000102868
etnk2
ethanolamine kinase 2
chr1_-_54420133 0.87 ENSDART00000190295
CABZ01043826.1

chr13_+_31402067 0.85 ENSDART00000019202
tdrd9
tudor domain containing 9
chr10_-_105100 0.84 ENSDART00000145716
ttc3
tetratricopeptide repeat domain 3
chr5_+_43470544 0.83 ENSDART00000111587
rhobtb2a
Rho-related BTB domain containing 2a
chr5_+_36932718 0.83 ENSDART00000037879
crx
cone-rod homeobox
chr11_+_40032790 0.82 ENSDART00000158809
si:dkey-264d12.1
si:dkey-264d12.1
chr3_-_42981739 0.82 ENSDART00000167844
mafk
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
chr19_+_33732487 0.80 ENSDART00000010294
runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_+_36314867 0.80 ENSDART00000176763
lrp1bb
low density lipoprotein receptor-related protein 1Bb
chr10_+_41159241 0.79 ENSDART00000141657
anxa4
annexin A4
chr24_-_3342665 0.79 ENSDART00000167682
sugct
succinyl-CoA:glutarate-CoA transferase
chr17_+_10748366 0.79 ENSDART00000018683
ENSDART00000097274
ATG14
zgc:113944
chr3_+_17744339 0.78 ENSDART00000132622
znf385c
zinc finger protein 385C
chr15_-_36533322 0.78 ENSDART00000156466
ENSDART00000121755
si:dkey-262k9.4
si:dkey-262k9.4
chr6_-_47953829 0.78 ENSDART00000157264
si:dkey-166d12.2
si:dkey-166d12.2
chr12_+_33038757 0.77 ENSDART00000153146
rbfox3a
RNA binding fox-1 homolog 3a
chr24_+_12074340 0.77 ENSDART00000170997
ENSDART00000166227
ccr9b
chemokine (C-C motif) receptor 9b
chr2_-_48171112 0.76 ENSDART00000156258
pfkpb
phosphofructokinase, platelet b
chr22_-_5099824 0.76 ENSDART00000122341
ENSDART00000161345
zfr2
zinc finger RNA binding protein 2
chr18_+_14693682 0.75 ENSDART00000132249
uri1
URI1, prefoldin-like chaperone
chr12_-_3453589 0.75 ENSDART00000175918
CABZ01063170.1

chr8_-_19649617 0.75 ENSDART00000189033
fam78bb
family with sequence similarity 78, member B b
chr21_+_25054420 0.75 ENSDART00000065132
zgc:171740
zgc:171740
chr11_-_15090564 0.75 ENSDART00000162079
slc1a8a
solute carrier family 1 (glutamate transporter), member 8a
chr17_-_24916889 0.75 ENSDART00000156157
si:ch211-195o20.7
si:ch211-195o20.7
chr3_-_40933415 0.74 ENSDART00000055201
foxk1
forkhead box K1
chr19_-_6774871 0.74 ENSDART00000170952
pvrl2l
poliovirus receptor-related 2 like
chr19_+_43119698 0.74 ENSDART00000167847
ENSDART00000186962
ENSDART00000187305
eef1a1l1
eukaryotic translation elongation factor 1 alpha 1, like 1
chr18_+_6126506 0.74 ENSDART00000125725
si:ch1073-390k14.1
si:ch1073-390k14.1
chr24_-_12981423 0.74 ENSDART00000133166
ENSDART00000131370
ENSDART00000002992
dcaf11
ddb1 and cul4 associated factor 11
chr6_-_57539141 0.73 ENSDART00000156967
itcha
itchy E3 ubiquitin protein ligase a
chr19_-_47832853 0.73 ENSDART00000170988
ago4
argonaute RISC catalytic component 4
chr13_-_280827 0.73 ENSDART00000144819
slc30a6
solute carrier family 30 (zinc transporter), member 6
chr7_-_36358303 0.73 ENSDART00000130028
fto
fat mass and obesity associated
chr8_-_47329755 0.73 ENSDART00000060853
pex10
peroxisomal biogenesis factor 10
chr17_-_7440397 0.72 ENSDART00000162597
grm1b
glutamate receptor, metabotropic 1b
chr6_-_7842078 0.72 ENSDART00000065507
plppr2b
phospholipid phosphatase related 2b
chr20_-_22378401 0.71 ENSDART00000011135
ENSDART00000110967
kita
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a
chr22_-_94352 0.70 ENSDART00000184883
ndufaf3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr16_+_48729947 0.70 ENSDART00000049051
brd2b
bromodomain containing 2b
chr16_-_13388821 0.70 ENSDART00000144062
grin2db
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr21_-_41617372 0.69 ENSDART00000187171
BX005397.1

chr12_+_30200652 0.69 ENSDART00000193405
ENSDART00000132335
ablim1b
actin binding LIM protein 1b
chr25_+_16945348 0.69 ENSDART00000016591
fgf6a
fibroblast growth factor 6a
chr7_-_36358735 0.68 ENSDART00000188392
fto
fat mass and obesity associated
chr1_-_30457062 0.68 ENSDART00000185318
ENSDART00000157924
ENSDART00000161380
igf2bp2b
insulin-like growth factor 2 mRNA binding protein 2b
chr5_-_26247215 0.68 ENSDART00000136806
erap1b
endoplasmic reticulum aminopeptidase 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of hey2_hey1+heyl

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:1904059 regulation of locomotor rhythm(GO:1904059)
1.1 3.3 GO:0014809 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.8 3.9 GO:1901073 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.8 3.0 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.6 3.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.6 2.5 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.5 1.4 GO:0042245 RNA repair(GO:0042245)
0.4 4.0 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.4 4.3 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.4 1.4 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.3 1.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.3 2.5 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.3 2.1 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.3 1.8 GO:0007343 egg activation(GO:0007343)
0.3 1.1 GO:0030224 monocyte differentiation(GO:0030224)
0.2 1.4 GO:0086013 membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.2 10.0 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 0.5 GO:1903504 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.2 1.1 GO:0001919 regulation of receptor recycling(GO:0001919)
0.2 2.0 GO:0046548 retinal rod cell development(GO:0046548)
0.2 0.7 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.2 1.0 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.2 1.6 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.2 1.3 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.2 0.6 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 1.6 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 1.2 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 0.4 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.1 0.4 GO:0033212 iron assimilation(GO:0033212)
0.1 1.6 GO:0038203 TORC2 signaling(GO:0038203)
0.1 1.4 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.1 5.8 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 1.4 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.1 0.8 GO:0007141 male meiosis I(GO:0007141)
0.1 0.9 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.8 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.9 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 1.5 GO:0032264 IMP salvage(GO:0032264)
0.1 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.3 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.1 17.1 GO:0007601 visual perception(GO:0007601)
0.1 0.6 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 0.3 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.1 0.5 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.1 1.1 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.1 1.7 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 0.6 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 1.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 1.6 GO:0015671 oxygen transport(GO:0015671)
0.1 2.7 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 2.1 GO:0006829 zinc II ion transport(GO:0006829)
0.1 0.3 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.8 GO:0006735 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 1.1 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 1.0 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.4 GO:0070375 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.1 1.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 2.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.2 GO:0044771 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.1 2.9 GO:0006096 glycolytic process(GO:0006096)
0.1 0.4 GO:0006788 heme oxidation(GO:0006788)
0.1 1.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 1.8 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 2.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 0.4 GO:0034650 cortisol metabolic process(GO:0034650)
0.1 0.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.3 GO:0071380 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.1 0.5 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.1 3.3 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.1 0.7 GO:0006670 sphingosine metabolic process(GO:0006670)
0.1 1.9 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.1 0.5 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.6 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.2 GO:0045124 regulation of bone resorption(GO:0045124)
0.0 1.1 GO:0060997 dendritic spine morphogenesis(GO:0060997) dendritic spine organization(GO:0097061)
0.0 1.0 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.8 GO:0010675 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.0 0.7 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.3 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.3 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 2.3 GO:0006986 response to unfolded protein(GO:0006986)
0.0 2.6 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 2.1 GO:0031017 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.0 0.2 GO:0048478 replication fork protection(GO:0048478)
0.0 0.7 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.0 GO:0099622 membrane repolarization during action potential(GO:0086011) cardiac muscle cell membrane repolarization(GO:0099622)
0.0 0.3 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 2.5 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 1.7 GO:0048484 enteric nervous system development(GO:0048484)
0.0 2.5 GO:0030042 actin filament depolymerization(GO:0030042)
0.0 0.3 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 0.1 GO:0042766 nucleosome mobilization(GO:0042766)
0.0 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.3 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.0 0.4 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.8 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.6 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.6 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 2.3 GO:0001666 response to hypoxia(GO:0001666)
0.0 0.6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.8 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 3.2 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.1 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.6 GO:0019835 cytolysis(GO:0019835)
0.0 0.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.2 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0014823 response to activity(GO:0014823)
0.0 0.7 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.5 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 1.1 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.6 GO:0045332 phospholipid translocation(GO:0045332)
0.0 4.8 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 1.4 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 1.4 GO:0071774 fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344) response to fibroblast growth factor(GO:0071774)
0.0 0.7 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.9 GO:0016358 dendrite development(GO:0016358)
0.0 4.6 GO:0006897 endocytosis(GO:0006897)
0.0 2.6 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 1.2 GO:0010506 regulation of autophagy(GO:0010506)
0.0 1.3 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 1.0 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.2 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.5 GO:0021854 hypothalamus development(GO:0021854)
0.0 1.5 GO:0035725 sodium ion transmembrane transport(GO:0035725)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.2 GO:0035517 PR-DUB complex(GO:0035517)
0.5 3.9 GO:0030428 cell septum(GO:0030428)
0.5 3.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.4 3.1 GO:0016586 RSC complex(GO:0016586)
0.3 1.7 GO:0071203 WASH complex(GO:0071203)
0.3 1.8 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.3 13.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.3 4.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 1.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.3 1.6 GO:0071986 Ragulator complex(GO:0071986)
0.2 1.3 GO:0070062 extracellular exosome(GO:0070062)
0.2 0.6 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.2 7.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.4 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.4 GO:0016600 flotillin complex(GO:0016600)
0.1 2.5 GO:0043195 terminal bouton(GO:0043195)
0.1 0.3 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 3.1 GO:0032590 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.1 0.7 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 1.1 GO:0044545 NSL complex(GO:0044545)
0.1 0.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.6 GO:0031932 TORC2 complex(GO:0031932)
0.1 3.1 GO:0031941 filamentous actin(GO:0031941)
0.1 0.5 GO:0030904 retromer complex(GO:0030904)
0.1 0.3 GO:1902636 kinociliary basal body(GO:1902636)
0.1 2.2 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.4 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 2.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.1 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 5.8 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.7 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 7.5 GO:0000785 chromatin(GO:0000785)
0.0 2.0 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0032432 actin filament bundle(GO:0032432)
0.0 1.6 GO:0042383 sarcolemma(GO:0042383)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 1.1 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.7 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.0 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.9 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.8 4.0 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.7 2.9 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.6 2.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.5 7.6 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.5 4.0 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.5 3.9 GO:0004100 chitin synthase activity(GO:0004100)
0.4 3.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.4 1.4 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.4 1.4 GO:0043734 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.3 1.4 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.3 1.6 GO:0050699 WW domain binding(GO:0050699)
0.3 1.1 GO:0004903 growth hormone receptor activity(GO:0004903)
0.3 2.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.3 1.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.2 1.6 GO:0098809 nitrite reductase activity(GO:0098809)
0.2 1.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 2.9 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.2 6.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 3.1 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.2 1.1 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.2 2.5 GO:0015295 solute:proton symporter activity(GO:0015295)
0.2 0.6 GO:0004774 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.2 1.3 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.2 8.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.2 0.6 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 1.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.4 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.1 4.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 1.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 1.5 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.0 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 5.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.9 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 0.5 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.1 9.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.7 GO:0099583 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 0.8 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 0.3 GO:0034618 arginine binding(GO:0034618)
0.1 2.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.5 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 1.6 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.1 3.2 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.1 0.5 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 1.4 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 1.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 1.1 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 1.0 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.7 GO:0035198 miRNA binding(GO:0035198)
0.1 4.0 GO:0071949 FAD binding(GO:0071949)
0.1 2.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.5 GO:0005035 death receptor activity(GO:0005035)
0.1 2.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.4 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.1 0.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.6 GO:0005522 profilin binding(GO:0005522)
0.1 0.2 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.1 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 6.7 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.1 0.3 GO:0035173 histone kinase activity(GO:0035173)
0.0 1.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.2 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.7 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 1.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.6 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.4 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0 0.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 1.3 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 3.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 4.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.8 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.7 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.4 GO:0045296 cadherin binding(GO:0045296)
0.0 0.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 2.3 GO:0015293 symporter activity(GO:0015293)
0.0 0.3 GO:0019239 deaminase activity(GO:0019239)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.6 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.0 GO:0052833 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.7 GO:0019955 cytokine binding(GO:0019955)
0.0 0.3 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 2.1 GO:0046982 protein heterodimerization activity(GO:0046982)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.3 4.3 PID CONE PATHWAY Visual signal transduction: Cones
0.2 2.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.4 2.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.3 6.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 3.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 3.8 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.2 2.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 4.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.2 3.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 1.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 0.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 1.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases