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PRJEB1986: zebrafish developmental stages transcriptome

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Results for hmbox1a+zgc:91944

Z-value: 0.73

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Transcription factors associated with hmbox1a+zgc:91944

Gene Symbol Gene ID Gene Info
hmbox1a
ENSDARG00000027082 homeobox containing 1a
zgc
ENSDARG00000035887 91944
hmbox1a
ENSDARG00000109287 homeobox containing 1 b
zgc
ENSDARG00000114642 91944

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CABZ01078261.1dr11_v1_chr20_+_49787584_497875840.474.3e-02Click!
zgc:91944dr11_v1_chr19_-_32600638_32600638-0.135.8e-01Click!
hmbox1adr11_v1_chr17_-_16324565_163245650.048.6e-01Click!

Activity profile of hmbox1a+zgc:91944 motif

Sorted Z-values of hmbox1a+zgc:91944 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_71758307 2.19 ENSDART00000161067
ENSDART00000165253
myom1b
myomesin 1b
chr11_+_43043171 1.52 ENSDART00000180344
CABZ01092982.1

chr7_+_35075847 1.44 ENSDART00000193469
ENSDART00000037346
ctrb1
chymotrypsinogen B1
chr4_-_77506362 1.31 ENSDART00000174387
ENSDART00000181181
CABZ01087415.1

chr15_-_17074393 1.00 ENSDART00000155526
si:ch211-24o10.6
si:ch211-24o10.6
chr4_+_72798545 0.91 ENSDART00000181727
MYRFL
myelin regulatory factor-like
chr19_-_40192249 0.90 ENSDART00000051972
grn1
granulin 1
chr12_+_34896956 0.89 ENSDART00000055415
prph2a
peripherin 2a (retinal degeneration, slow)
chr3_+_39540014 0.86 ENSDART00000074848
zgc:165423
zgc:165423
chr23_-_44786844 0.79 ENSDART00000148669
si:ch73-269m23.5
si:ch73-269m23.5
chr3_-_31079186 0.79 ENSDART00000145636
ENSDART00000140569
ELOB (1 of many)
elob
elongin B
elongin B
chr17_-_24919297 0.78 ENSDART00000154424
zgc:193593
zgc:193593
chr17_-_36896560 0.71 ENSDART00000045287
mapre3a
microtubule-associated protein, RP/EB family, member 3a
chr8_+_39724138 0.70 ENSDART00000009323
pla2g1b
phospholipase A2, group IB (pancreas)
chr24_+_9178064 0.69 ENSDART00000142971
dlgap1b
discs, large (Drosophila) homolog-associated protein 1b
chr7_+_2849020 0.68 ENSDART00000168695
BX004857.1

chr23_-_11130683 0.68 ENSDART00000181189
cntn3a.2
contactin 3a, tandem duplicate 2
chr19_+_9174166 0.67 ENSDART00000104637
ENSDART00000150968
si:ch211-81a5.8
si:ch211-81a5.8
chr4_+_76509294 0.67 ENSDART00000099899
ms4a17a.17
membrane-spanning 4-domains, subfamily A, member 17A.17
chr3_-_18675688 0.66 ENSDART00000048218
slc5a11
solute carrier family 5 (sodium/inositol cotransporter), member 11
chr25_+_35706493 0.64 ENSDART00000176741
kif21a
kinesin family member 21A
chr20_-_47051996 0.62 ENSDART00000153330
dnmt3aa
DNA (cytosine-5-)-methyltransferase 3 alpha a
chr16_+_45930962 0.59 ENSDART00000124689
ENSDART00000041811
otud7b
OTU deubiquitinase 7B
chr25_+_25737386 0.57 ENSDART00000108476
lrrc61
leucine rich repeat containing 61
chr1_-_9641845 0.57 ENSDART00000121490
ENSDART00000159411
ugt5b2
ugt5b3
UDP glucuronosyltransferase 5 family, polypeptide B2
UDP glucuronosyltransferase 5 family, polypeptide B3
chr5_-_12687357 0.56 ENSDART00000193206
aifm3
apoptosis-inducing factor, mitochondrion-associated, 3
chr3_+_49043917 0.56 ENSDART00000158212
zgc:92161
zgc:92161
chr8_-_37328112 0.55 ENSDART00000140365
slc12a5b
solute carrier family 12 (potassium/chloride transporter), member 5b
chr17_-_15188440 0.54 ENSDART00000151885
wdhd1
WD repeat and HMG-box DNA binding protein 1
chr5_-_61624693 0.54 ENSDART00000141323
si:dkey-261j4.4
si:dkey-261j4.4
chr18_+_9615147 0.53 ENSDART00000160284
pclob
piccolo presynaptic cytomatrix protein b
chr20_-_7133546 0.53 ENSDART00000160910
si:ch211-121a2.4
si:ch211-121a2.4
chr9_-_54248182 0.52 ENSDART00000129540
larsa
leucyl-tRNA synthetase a
chr7_+_41295974 0.52 ENSDART00000173568
ENSDART00000173544
si:dkey-86l18.10
si:dkey-86l18.10
chr20_-_1378514 0.51 ENSDART00000181830
scara5
scavenger receptor class A, member 5 (putative)
chr23_-_14766902 0.51 ENSDART00000168113
gss
glutathione synthetase
chr13_+_46718518 0.51 ENSDART00000160401
ENSDART00000182884
tmem63ba
transmembrane protein 63Ba
chr24_-_8887825 0.51 ENSDART00000066781
elovl2
ELOVL fatty acid elongase 2
chr1_+_53374454 0.51 ENSDART00000038807
ucp1
uncoupling protein 1
chr10_+_4874542 0.51 ENSDART00000101431
palm2
paralemmin 2
chr21_-_22474362 0.50 ENSDART00000169659
myo5b
myosin VB
chr10_+_439692 0.49 ENSDART00000147740
zdhhc8a
zinc finger, DHHC-type containing 8a
chr18_+_11506561 0.49 ENSDART00000121647
PRMT8
protein arginine methyltransferase 8
chr18_-_341489 0.49 ENSDART00000168333
si:ch1073-83b15.1
si:ch1073-83b15.1
chr21_-_42097736 0.49 ENSDART00000100000
gabra1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr7_-_71758613 0.48 ENSDART00000166724
myom1b
myomesin 1b
chr13_+_1542493 0.47 ENSDART00000181968
CABZ01044281.1

chr24_-_29868151 0.47 ENSDART00000184802
aglb
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase b
chr18_+_13077800 0.46 ENSDART00000161153
GAN
gigaxonin
chr2_+_2503396 0.45 ENSDART00000168418
crhr2
corticotropin releasing hormone receptor 2
chr18_-_2727764 0.45 ENSDART00000160841
ARHGEF17
si:ch211-248g20.5
chr9_-_34986827 0.44 ENSDART00000137862
si:ch211-160b11.4
si:ch211-160b11.4
chr19_+_24394560 0.43 ENSDART00000142506
si:dkey-81h8.1
si:dkey-81h8.1
chr5_+_20257225 0.43 ENSDART00000127919
ssh1a
slingshot protein phosphatase 1a
chr7_+_19016023 0.43 ENSDART00000185212
CU972454.5

chr19_-_25271155 0.43 ENSDART00000104027
rims3
regulating synaptic membrane exocytosis 3
chr17_+_33375469 0.42 ENSDART00000032827
zgc:162964
zgc:162964
chr19_+_43669122 0.42 ENSDART00000139151
si:ch211-193k19.1
si:ch211-193k19.1
chr13_-_21660203 0.41 ENSDART00000100925
mxtx1
mix-type homeobox gene 1
chr16_-_46587938 0.41 ENSDART00000181433
BX323793.1

chr19_+_823945 0.41 ENSDART00000142287
ppp1r18
protein phosphatase 1, regulatory subunit 18
chr21_+_33459524 0.40 ENSDART00000053205
cd74b
CD74 molecule, major histocompatibility complex, class II invariant chain b
chr11_-_29650930 0.39 ENSDART00000166969
chd5
chromodomain helicase DNA binding protein 5
chr17_-_47142249 0.39 ENSDART00000184705
CU915775.1

chr2_+_55914699 0.38 ENSDART00000157905
atcayb
ataxia, cerebellar, Cayman type b
chr19_+_9295244 0.37 ENSDART00000132255
ENSDART00000144299
si:ch73-15n24.1
si:ch73-15n24.1
chr1_+_44395976 0.37 ENSDART00000159686
ENSDART00000189905
ENSDART00000025145
unc93b1
unc-93 homolog B1, TLR signaling regulator
chr14_-_29858883 0.36 ENSDART00000141034
sorbs2b
sorbin and SH3 domain containing 2b
chr13_-_37620091 0.36 ENSDART00000135875
ENSDART00000193270
ENSDART00000018064
zgc:152791
zgc:152791
chr11_+_11030908 0.35 ENSDART00000111091
pla2r1
phospholipase A2 receptor 1
chr10_-_44508249 0.34 ENSDART00000160018
DUSP26
dual specificity phosphatase 26
chr23_-_30960506 0.33 ENSDART00000142661
osbpl2a
oxysterol binding protein-like 2a
chr21_+_5635420 0.33 ENSDART00000168158
shroom3
shroom family member 3
chr2_-_48966431 0.32 ENSDART00000147948
kcnj9
potassium inwardly-rectifying channel, subfamily J, member 9
chr2_-_3403020 0.32 ENSDART00000092741
snap47
synaptosomal-associated protein, 47
chr12_-_13650344 0.32 ENSDART00000124364
ENSDART00000124638
ENSDART00000171929
stat5b
signal transducer and activator of transcription 5b
chr14_+_21222287 0.32 ENSDART00000159905
si:ch211-175m2.4
si:ch211-175m2.4
chr24_-_7321928 0.32 ENSDART00000167570
ENSDART00000045150
actr3b
ARP3 actin related protein 3 homolog B
chr19_+_31585917 0.32 ENSDART00000132182
gmnn
geminin, DNA replication inhibitor
chr12_+_29054907 0.32 ENSDART00000152936
gabrz
gamma-aminobutyric acid (GABA) A receptor, zeta
chr11_+_1764203 0.30 ENSDART00000173023
lrp1aa
low density lipoprotein receptor-related protein 1Aa
chr12_+_30200652 0.30 ENSDART00000193405
ENSDART00000132335
ablim1b
actin binding LIM protein 1b
chr14_+_23709134 0.30 ENSDART00000191162
ENSDART00000179754
ENSDART00000054266
gnpda1
glucosamine-6-phosphate deaminase 1
chr7_+_13609457 0.30 ENSDART00000172857
ankdd1a
ankyrin repeat and death domain containing 1A
chr23_+_26946429 0.30 ENSDART00000185564
cacnb3b
calcium channel, voltage-dependent, beta 3b
chr8_+_53064920 0.30 ENSDART00000164823
nadka
NAD kinase a
chr10_-_28513861 0.29 ENSDART00000177781
bbx
bobby sox homolog (Drosophila)
chr7_+_36467796 0.29 ENSDART00000146202
aktip
akt interacting protein
chr19_+_31585341 0.29 ENSDART00000052185
gmnn
geminin, DNA replication inhibitor
chr11_-_1400507 0.28 ENSDART00000173029
ENSDART00000172953
ENSDART00000111140
rpl29
ribosomal protein L29
chr22_-_8388678 0.28 ENSDART00000184389
CABZ01061498.1

chr12_+_10631266 0.28 ENSDART00000161455
csf3a
colony stimulating factor 3 (granulocyte) a
chr18_-_502722 0.28 ENSDART00000185757
sdr42e1
short chain dehydrogenase/reductase family 42E, member 1
chr7_+_65261576 0.28 ENSDART00000169566
bco1
beta-carotene oxygenase 1
chr12_-_19153177 0.28 ENSDART00000057125
tefa
thyrotrophic embryonic factor a
chr13_-_36050303 0.27 ENSDART00000134955
ENSDART00000139087
lgmn
legumain
chr12_-_20665164 0.27 ENSDART00000105352
gip
gastric inhibitory polypeptide
chr12_-_26538823 0.27 ENSDART00000143213
acsf2
acyl-CoA synthetase family member 2
chr8_+_10339869 0.27 ENSDART00000132253
tbc1d22b
TBC1 domain family, member 22B
chr16_-_48071632 0.27 ENSDART00000148564
CSMD3 (1 of many)
si:ch211-236p22.1
chr12_+_35654749 0.26 ENSDART00000169889
ENSDART00000167873
baiap2b
BAI1-associated protein 2b
chr4_+_26056548 0.26 ENSDART00000171204
SCYL2
si:ch211-244b2.1
chr7_-_38570878 0.26 ENSDART00000139187
ENSDART00000134570
ENSDART00000041055
celf1
cugbp, Elav-like family member 1
chr6_+_10450000 0.26 ENSDART00000151288
ENSDART00000187431
ENSDART00000192474
ENSDART00000188214
ENSDART00000184766
ENSDART00000190082
kcnh7
potassium channel, voltage gated eag related subfamily H, member 7
chr13_+_8693410 0.25 ENSDART00000138448
ttc7a
tetratricopeptide repeat domain 7A
chr14_+_16151636 0.25 ENSDART00000159352
polr1a
polymerase (RNA) I polypeptide A
chr24_-_18809433 0.25 ENSDART00000152009
arfgef1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr3_-_11878490 0.25 ENSDART00000129961
coro7
coronin 7
chr7_-_18416741 0.24 ENSDART00000097882
sstr1b
somatostatin receptor 1b
chr23_-_23160088 0.24 ENSDART00000141853
noc2l
NOC2-like nucleolar associated transcriptional repressor
chr24_-_20321012 0.24 ENSDART00000163683
map3k20
mitogen-activated protein kinase kinase kinase 20
chr3_+_15805917 0.24 ENSDART00000055834
phospho1
phosphatase, orphan 1
chr2_+_49713592 0.24 ENSDART00000189624
BX323861.3

chr13_-_8279533 0.24 ENSDART00000109666
si:ch211-250c4.5
si:ch211-250c4.5
chr14_-_29859067 0.24 ENSDART00000136380
sorbs2b
sorbin and SH3 domain containing 2b
chr17_+_25197180 0.24 ENSDART00000148775
arhgef10
Rho guanine nucleotide exchange factor (GEF) 10
chr8_+_14890821 0.24 ENSDART00000190966
soat1
sterol O-acyltransferase 1
chr24_-_35269991 0.24 ENSDART00000185424
sntg1
syntrophin, gamma 1
chr6_-_30658755 0.23 ENSDART00000065215
ENSDART00000181302
lurap1
leucine rich adaptor protein 1
chr8_+_7144066 0.22 ENSDART00000146306
slc6a6a
solute carrier family 6 (neurotransmitter transporter), member 6a
chr4_-_45100253 0.22 ENSDART00000163870
si:dkey-51d8.3
si:dkey-51d8.3
chr2_-_43191465 0.22 ENSDART00000025254
crema
cAMP responsive element modulator a
chr6_-_30683637 0.21 ENSDART00000065212
ttc4
tetratricopeptide repeat domain 4
chr8_+_30699429 0.21 ENSDART00000005345
upb1
ureidopropionase, beta
chr20_-_30377221 0.21 ENSDART00000126229
rps7
ribosomal protein S7
chr1_-_11372456 0.21 ENSDART00000144164
ENSDART00000141238
sdk1b
sidekick cell adhesion molecule 1b
chr3_-_30186296 0.21 ENSDART00000134395
ENSDART00000077057
ENSDART00000017422
tbc1d17
TBC1 domain family, member 17
chr7_+_53199763 0.20 ENSDART00000160097
cdh28
cadherin 28
chr8_-_11546175 0.20 ENSDART00000081909
si:ch211-248e11.2
si:ch211-248e11.2
chr2_+_23677179 0.20 ENSDART00000153918
oxsr1a
oxidative stress responsive 1a
chr10_-_22912255 0.20 ENSDART00000131992
si:ch1073-143l10.2
si:ch1073-143l10.2
chr11_-_40030139 0.20 ENSDART00000021916
uts2b
urotensin 2, beta
chr9_+_29643036 0.20 ENSDART00000023210
ENSDART00000175160
trim13
tripartite motif containing 13
chr5_+_19448078 0.20 ENSDART00000088968
ube3b
ubiquitin protein ligase E3B
chr10_+_35952532 0.20 ENSDART00000184730
rtn4rl1a
reticulon 4 receptor-like 1a
chr13_+_40019001 0.19 ENSDART00000158820
golga7bb
golgin A7 family, member Bb
chr12_+_40945319 0.19 ENSDART00000183435
CDH18
cadherin 18
chr7_-_27037990 0.19 ENSDART00000173561
nucb2a
nucleobindin 2a
chr2_-_45331115 0.19 ENSDART00000158003
si:dkey-13n23.3
si:dkey-13n23.3
chr21_-_4923427 0.19 ENSDART00000181489
kcnt1
potassium channel, subfamily T, member 1
chr18_-_30021479 0.19 ENSDART00000144562
si:ch211-220f16.2
si:ch211-220f16.2
chr2_+_29491314 0.19 ENSDART00000181774
dlgap1a
discs, large (Drosophila) homolog-associated protein 1a
chr23_+_26946744 0.19 ENSDART00000115141
cacnb3b
calcium channel, voltage-dependent, beta 3b
chr25_-_19486399 0.19 ENSDART00000155076
ENSDART00000156016
zgc:193812
zgc:193812
chr9_-_49805218 0.18 ENSDART00000179290
GALNT3
polypeptide N-acetylgalactosaminyltransferase 3
chr8_+_21384288 0.18 ENSDART00000079263
fhad1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr11_-_36230146 0.18 ENSDART00000135888
ENSDART00000189782
rrp9
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
chr21_-_37973081 0.17 ENSDART00000136569
ripply1
ripply transcriptional repressor 1
chr19_-_22328154 0.17 ENSDART00000090464
si:ch73-196l6.5
si:ch73-196l6.5
chr2_-_30460293 0.17 ENSDART00000113193
cbln2a
cerebellin 2a precursor
chr20_-_456998 0.17 ENSDART00000149973
frk
fyn-related Src family tyrosine kinase
chr2_+_11029138 0.16 ENSDART00000138737
ENSDART00000081058
ENSDART00000153662
acot11a
acyl-CoA thioesterase 11a
chr6_-_48473694 0.16 ENSDART00000154237
ppm1j
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr20_+_53522059 0.16 ENSDART00000147570
pak6b
p21 protein (Cdc42/Rac)-activated kinase 6b
chr5_-_13564961 0.16 ENSDART00000146827
si:ch211-230g14.3
si:ch211-230g14.3
chr4_+_20566371 0.16 ENSDART00000127576
BX248410.1

chr13_+_48359573 0.16 ENSDART00000161959
ENSDART00000165311
msh6
mutS homolog 6 (E. coli)
chr18_-_8857137 0.16 ENSDART00000126331
prrt4
proline-rich transmembrane protein 4
chr17_-_25382367 0.15 ENSDART00000162306
ENSDART00000165282
lck
LCK proto-oncogene, Src family tyrosine kinase
chr12_+_35011899 0.15 ENSDART00000153007
ENSDART00000153020
qki2
QKI, KH domain containing, RNA binding 2
chr23_+_41679586 0.15 ENSDART00000067662
CU914487.1

chr2_-_24061575 0.15 ENSDART00000089234
slc12a7a
solute carrier family 12 (potassium/chloride transporter), member 7a
chr4_+_71989418 0.15 ENSDART00000170996
parp11
poly(ADP-ribose) polymerase family member 11
chr10_-_22095505 0.15 ENSDART00000140210
ponzr10
plac8 onzin related protein 10
chr22_-_16755885 0.15 ENSDART00000036467
patj
PATJ, crumbs cell polarity complex component
chr3_-_60827402 0.15 ENSDART00000053494
anks4b
ankyrin repeat and sterile alpha motif domain containing 4B
chr13_+_15190677 0.15 ENSDART00000142240
ENSDART00000129045
mavs
mitochondrial antiviral signaling protein
chr15_+_44366556 0.14 ENSDART00000133449
GUCY1A2
guanylate cyclase 1 soluble subunit alpha 2
chr7_-_16195144 0.14 ENSDART00000173492
btr04
bloodthirsty-related gene family, member 4
chr6_-_31325400 0.14 ENSDART00000188869
dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr11_+_44622019 0.14 ENSDART00000159618
rbm34
RNA binding motif protein 34
chr16_-_43011470 0.14 ENSDART00000131898
ENSDART00000142003
ENSDART00000017966
nudt17
nudix (nucleoside diphosphate linked moiety X)-type motif 17
chr13_-_18548729 0.14 ENSDART00000187686
BX908770.1

chr6_+_4160579 0.14 ENSDART00000105278
ENSDART00000187932
ENSDART00000111817
trim25l
tripartite motif containing 25, like
chr22_+_19366866 0.14 ENSDART00000137301
si:dkey-21e2.12
si:dkey-21e2.12
chr21_-_4922981 0.13 ENSDART00000191819
ENSDART00000113556
ENSDART00000193269
ENSDART00000182961
kcnt1
potassium channel, subfamily T, member 1
chr14_+_31498439 0.13 ENSDART00000173281
phf6
PHD finger protein 6
chr13_-_31938512 0.13 ENSDART00000026726
ENSDART00000182666
diexf
digestive organ expansion factor homolog
chr8_-_36112278 0.13 ENSDART00000183283
CT583723.1

chr18_-_31051847 0.13 ENSDART00000170982
gas8
growth arrest-specific 8
chr24_+_12133814 0.13 ENSDART00000158562
ENSDART00000159029
ENSDART00000168248
lztfl1
leucine zipper transcription factor-like 1
chr4_-_1908179 0.13 ENSDART00000139586
ano6
anoctamin 6
chr22_-_17586064 0.13 ENSDART00000060786
ENSDART00000188303
ENSDART00000181212
ENSDART00000181951
pip5k1ca
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a
chr2_-_2957970 0.13 ENSDART00000162505
si:ch1073-82l19.1
si:ch1073-82l19.1
chr10_+_45302425 0.13 ENSDART00000159954
zmiz2
zinc finger, MIZ-type containing 2
chr25_+_4750972 0.13 ENSDART00000168903
si:zfos-2372e4.1
si:zfos-2372e4.1
chr22_-_17585618 0.13 ENSDART00000183123
pip5k1ca
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a
chr5_-_67799821 0.12 ENSDART00000017881
eif4e1b
eukaryotic translation initiation factor 4E family member 1B
chr17_-_37184655 0.12 ENSDART00000180447
asxl2
additional sex combs like transcriptional regulator 2
chr5_+_36439405 0.12 ENSDART00000102973
eda
ectodysplasin A
chr1_-_513762 0.12 ENSDART00000148162
ENSDART00000144606
trmt10c
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr15_-_23814330 0.12 ENSDART00000153843
si:ch211-167j9.5
si:ch211-167j9.5
chr16_+_43401005 0.12 ENSDART00000110994
sqlea
squalene epoxidase a
chr4_-_14486822 0.12 ENSDART00000048821
plxnb2a
plexin b2a
chr17_+_17861681 0.12 ENSDART00000123311
ism2a
isthmin 2a
chr7_+_65813301 0.12 ENSDART00000187449
ENSDART00000179834
ENSDART00000082740
ENSDART00000178627
tead1b
TEA domain family member 1b
chr6_+_37441789 0.12 ENSDART00000157317
gtpbp6
GTP binding protein 6 (putative)
chr17_+_5985933 0.12 ENSDART00000190844
zgc:194275
zgc:194275
chr19_-_5669122 0.12 ENSDART00000112211
si:ch211-264f5.2
si:ch211-264f5.2
chr5_-_11809404 0.11 ENSDART00000132564
nf2a
neurofibromin 2a (merlin)

Network of associatons between targets according to the STRING database.

First level regulatory network of hmbox1a+zgc:91944

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0060907 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.5 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 0.5 GO:0003245 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.4 GO:0034154 toll-like receptor 3 signaling pathway(GO:0034138) toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.6 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.3 GO:0006043 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.1 0.5 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.7 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 0.5 GO:0070206 protein trimerization(GO:0070206)
0.1 0.3 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.3 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.1 0.3 GO:0061113 endodermal digestive tract morphogenesis(GO:0061031) pancreas morphogenesis(GO:0061113)
0.1 0.5 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.5 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.3 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.5 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.2 GO:0006290 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.9 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 0.7 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.1 GO:0072526 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.0 0.1 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.4 GO:0042214 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0019483 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.0 0.2 GO:0039694 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.0 0.1 GO:0097435 fibril organization(GO:0097435)
0.0 0.1 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.4 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.5 GO:0044247 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus(GO:0039528) cellular response to virus(GO:0098586)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.2 GO:0034434 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0 0.7 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.6 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.2 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.7 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.2 GO:0071385 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.1 GO:0035889 otolith tethering(GO:0035889)
0.0 0.6 GO:0001757 somite specification(GO:0001757)
0.0 1.1 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.2 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)
0.0 0.3 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.3 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.2 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.5 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.3 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.0 2.7 GO:0006936 muscle contraction(GO:0006936)
0.0 0.2 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 0.3 GO:0001843 neural tube closure(GO:0001843) primary neural tube formation(GO:0014020)
0.0 0.1 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.0 0.3 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.1 GO:1903828 negative regulation of cellular protein localization(GO:1903828)
0.0 0.3 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.1 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.5 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.2 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0030891 VCB complex(GO:0030891)
0.1 2.7 GO:0031430 M band(GO:0031430)
0.1 0.2 GO:0030689 Noc complex(GO:0030689)
0.1 0.5 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 0.2 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 0.9 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.7 GO:0043195 terminal bouton(GO:0043195)
0.0 0.9 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.4 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.5 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.5 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.5 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.1 0.5 GO:0043295 glutathione binding(GO:0043295)
0.1 0.3 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 0.3 GO:0031956 medium-chain fatty acid-CoA ligase activity(GO:0031956) butyrate-CoA ligase activity(GO:0047760)
0.1 0.2 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 0.3 GO:0031769 glucagon receptor binding(GO:0031769)
0.1 0.2 GO:0032404 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.0 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.4 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.5 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.4 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.0 0.5 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.7 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.7 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 0.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.0 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.0 0.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 2.6 GO:0019900 kinase binding(GO:0019900)
0.0 2.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.0 GO:0004945 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.0 0.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.6 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.2 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 0.7 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.6 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.5 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway