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PRJEB1986: zebrafish developmental stages transcriptome

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Results for hnf1a

Z-value: 2.51

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Transcription factors associated with hnf1a

Gene Symbol Gene ID Gene Info
hnf1a
ENSDARG00000009470 HNF1 homeobox a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hnf1adr11_v1_chr8_+_39802506_398025060.077.9e-01Click!

Activity profile of hnf1a motif

Sorted Z-values of hnf1a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_35066457 14.42 ENSDART00000058067
zgc:112160
zgc:112160
chr4_+_18804317 11.66 ENSDART00000101043
slc26a3.2
solute carrier family 26 (anion exchanger), member 3, tandem duplicate 2
chr5_-_30620625 10.38 ENSDART00000098273
tcnl
transcobalamin like
chr24_-_4765740 10.27 ENSDART00000121576
cpb1
carboxypeptidase B1 (tissue)
chr5_+_45677781 9.71 ENSDART00000163120
ENSDART00000126537
gc
group-specific component (vitamin D binding protein)
chr1_-_59348118 9.50 ENSDART00000170901
cyp3a65
cytochrome P450, family 3, subfamily A, polypeptide 65
chr9_-_9982696 8.77 ENSDART00000192548
ENSDART00000125852
ugt1ab
UDP glucuronosyltransferase 1 family a, b
chr9_-_9977827 8.17 ENSDART00000187315
ENSDART00000010246
ugt1ab
UDP glucuronosyltransferase 1 family a, b
chr6_-_39344259 7.23 ENSDART00000104074
zgc:158846
zgc:158846
chr20_+_35473288 7.12 ENSDART00000047195
mep1a.1
meprin A, alpha (PABA peptide hydrolase), tandem duplicate 1
chr6_+_30456788 6.10 ENSDART00000121492
FP236735.1

chr7_-_29534001 6.03 ENSDART00000124028
anxa2b
annexin A2b
chr21_+_40092301 5.98 ENSDART00000145150
serpinf2a
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a
chr20_-_40750953 5.70 ENSDART00000061256
cx28.9
connexin 28.9
chr3_+_31039923 5.28 ENSDART00000147706
cox6a2
cytochrome c oxidase subunit VIa polypeptide 2
chr8_-_40555340 5.15 ENSDART00000163348
NPC1L1
NPC1 like intracellular cholesterol transporter 1
chr5_+_28848870 5.13 ENSDART00000149563
zgc:174259
zgc:174259
chr12_+_6117682 5.02 ENSDART00000146650
asah2
N-acylsphingosine amidohydrolase 2
chr6_+_34028532 4.96 ENSDART00000155827
si:ch73-185c24.2
si:ch73-185c24.2
chr14_+_31721171 4.43 ENSDART00000173034
adgrg4a
adhesion G protein-coupled receptor G4a
chr11_-_23332592 4.39 ENSDART00000125024
golt1a
golgi transport 1A
chr5_+_9382301 4.34 ENSDART00000124017
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr5_+_28849155 4.24 ENSDART00000079090
zgc:174259
zgc:174259
chr9_+_27339505 4.21 ENSDART00000011822
slc10a2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr7_+_2849020 4.16 ENSDART00000168695
BX004857.1

chr5_+_28830643 4.15 ENSDART00000051448
serpina7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr12_-_6172154 4.06 ENSDART00000185434
a1cf
apobec1 complementation factor
chr12_-_6177894 3.97 ENSDART00000152292
a1cf
apobec1 complementation factor
chr4_+_7827261 3.79 ENSDART00000129568
phyh
phytanoyl-CoA 2-hydroxylase
chr5_+_28830388 3.75 ENSDART00000149150
serpina7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr6_+_38381957 3.60 ENSDART00000087300
gabrb3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr2_-_41942666 3.54 ENSDART00000075673
ebi3
Epstein-Barr virus induced 3
chr4_-_9533345 3.51 ENSDART00000128501
si:ch73-139j3.4
si:ch73-139j3.4
chr5_+_9405283 3.44 ENSDART00000127306
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr13_+_23988442 3.43 ENSDART00000010918
agt
angiotensinogen
chr1_-_12126535 3.30 ENSDART00000164817
ENSDART00000015251
mttp
microsomal triglyceride transfer protein
chr5_+_9377005 3.24 ENSDART00000124924
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr16_+_34531486 3.08 ENSDART00000043291
paqr7b
progestin and adipoQ receptor family member VII, b
chr2_-_23778180 3.04 ENSDART00000136782
si:dkey-24c2.7
si:dkey-24c2.7
chr8_+_16990120 3.02 ENSDART00000018934
pde4d
phosphodiesterase 4D, cAMP-specific
chr5_-_37886063 2.92 ENSDART00000131378
ENSDART00000132152
si:ch211-139a5.9
si:ch211-139a5.9
chr24_-_39610585 2.87 ENSDART00000066506
cox6b1
cytochrome c oxidase subunit VIb polypeptide 1
chr6_+_41039166 2.87 ENSDART00000125659
entpd8
ectonucleoside triphosphate diphosphohydrolase 8
chr17_-_7371564 2.80 ENSDART00000060336
rab32b
RAB32b, member RAS oncogene family
chr11_-_37997419 2.63 ENSDART00000102870
slc41a1
solute carrier family 41 (magnesium transporter), member 1
chr12_+_35067863 2.55 ENSDART00000152849
syt15
synaptotagmin XV
chr14_-_41556720 2.49 ENSDART00000149244
itga6l
integrin, alpha 6, like
chr18_+_15644559 2.45 ENSDART00000061794
nr1h4
nuclear receptor subfamily 1, group H, member 4
chr15_-_23467750 2.45 ENSDART00000148804
pdzd3a
PDZ domain containing 3a
chr5_+_9417409 2.45 ENSDART00000125421
ENSDART00000130265
ugt2b5
UDP glucuronosyltransferase 2 family, polypeptide B5
chr12_+_31673588 2.39 ENSDART00000152971
dnmbp
dynamin binding protein
chr4_-_12766418 2.39 ENSDART00000024312
dera
deoxyribose-phosphate aldolase (putative)
chr10_+_21867307 2.37 ENSDART00000126629
cbln17
cerebellin 17
chr4_-_34480599 2.26 ENSDART00000159602
ENSDART00000182248
si:dkeyp-51g9.4
si:ch211-64i20.3
si:dkeyp-51g9.4
si:ch211-64i20.3
chr7_+_40205394 2.25 ENSDART00000173742
ENSDART00000148390
ncapg2
non-SMC condensin II complex, subunit G2
chr18_+_3530769 2.18 ENSDART00000163469
si:ch73-338a16.3
si:ch73-338a16.3
chr7_-_4296771 2.17 ENSDART00000128855
cbln11
cerebellin 11
chr8_+_50742975 2.12 ENSDART00000155664
ENSDART00000160612
si:ch73-6l19.2
si:ch73-6l19.2
chr10_+_2981090 2.08 ENSDART00000111830
zfyve16
zinc finger, FYVE domain containing 16
chr12_+_47044707 2.08 ENSDART00000186506
zranb1a
zinc finger, RAN-binding domain containing 1a
chr15_-_33964897 2.07 ENSDART00000172075
ENSDART00000158126
ENSDART00000160456
lsr
lipolysis stimulated lipoprotein receptor
chr5_+_28858345 2.05 ENSDART00000111180
si:ch211-186e20.2
si:ch211-186e20.2
chr21_+_10076203 2.03 ENSDART00000190383
CABZ01043506.1

chr9_-_1459985 2.02 ENSDART00000124777
osbpl6
oxysterol binding protein-like 6
chr5_-_65158203 2.01 ENSDART00000171656
sh2d3cb
SH2 domain containing 3Cb
chr1_-_19502322 2.00 ENSDART00000181888
ENSDART00000044030
kitb
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr5_+_4054704 1.97 ENSDART00000140537
dhrs11a
dehydrogenase/reductase (SDR family) member 11a
chr2_+_49417900 1.96 ENSDART00000122742
ENSDART00000160783
rorcb
RAR-related orphan receptor C b
chr5_+_9428876 1.95 ENSDART00000081791
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr6_+_40723554 1.91 ENSDART00000103833
slc26a6l
solute carrier family 26, member 6, like
chr22_-_36770649 1.89 ENSDART00000169442
acy1
aminoacylase 1
chr10_-_41664427 1.86 ENSDART00000150213
ggt1b
gamma-glutamyltransferase 1b
chr25_+_4091067 1.80 ENSDART00000104926
eps8l2
EPS8 like 2
chr19_-_31042570 1.77 ENSDART00000144337
ENSDART00000136213
ENSDART00000133101
ENSDART00000190949
bzw2
basic leucine zipper and W2 domains 2
chr11_-_2270069 1.74 ENSDART00000189005
znf740a
zinc finger protein 740a
chr12_+_5209822 1.73 ENSDART00000152610
SLC35G1
si:ch211-197g18.2
chr6_-_47953829 1.72 ENSDART00000157264
si:dkey-166d12.2
si:dkey-166d12.2
chr6_-_59563597 1.72 ENSDART00000166311
INHBE
inhibin beta E subunit
chr5_+_29851433 1.71 ENSDART00000143434
ubash3ba
ubiquitin associated and SH3 domain containing Ba
chr12_+_2648043 1.70 ENSDART00000082220
gdf2
growth differentiation factor 2
chr16_+_11603096 1.68 ENSDART00000146286
si:dkey-11o1.3
si:dkey-11o1.3
chr8_+_1187928 1.66 ENSDART00000127252
slc35d2
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr17_-_34952562 1.66 ENSDART00000021128
kidins220a
kinase D-interacting substrate 220a
chr16_+_11623956 1.65 ENSDART00000137788
cxcr3.1
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr8_+_999421 1.62 ENSDART00000149528
fabp1b.1
fatty acid binding protein 1b, tandem duplicate 1
chr19_-_22387141 1.61 ENSDART00000151234
eppk1
epiplakin 1
chr3_+_26734162 1.60 ENSDART00000114552
si:dkey-202l16.5
si:dkey-202l16.5
chr1_-_9134045 1.59 ENSDART00000142132
palb2
partner and localizer of BRCA2
chr22_-_23625351 1.58 ENSDART00000192588
ENSDART00000163423
cfhl4
complement factor H like 4
chr15_+_14109652 1.58 ENSDART00000156370
clca1
chloride channel accessory 1
chr21_+_38002879 1.57 ENSDART00000065183
cldn2
claudin 2
chr21_+_39100289 1.56 ENSDART00000075958
slc13a2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr24_-_23675446 1.56 ENSDART00000066644
hnf4g
hepatocyte nuclear factor 4, gamma
chr15_+_29283981 1.55 ENSDART00000099895
rap1gap2a
RAP1 GTPase activating protein 2a
chr3_+_49097775 1.55 ENSDART00000169185
zgc:123284
zgc:123284
chr15_-_17868870 1.53 ENSDART00000170950
atf5b
activating transcription factor 5b
chr5_+_26795773 1.52 ENSDART00000145631
tcn2
transcobalamin II
chr25_+_19238175 1.51 ENSDART00000110730
ENSDART00000193619
ENSDART00000154420
ppip5k1b
diphosphoinositol pentakisphosphate kinase 1b
chr3_+_49521106 1.50 ENSDART00000162799
crb3a
crumbs homolog 3a
chr25_+_7670683 1.50 ENSDART00000040275
kcnj11l
potassium inwardly-rectifying channel, subfamily J, member 11, like
chr13_-_42579437 1.49 ENSDART00000135172
fam83ha
family with sequence similarity 83, member Ha
chr19_-_22568203 1.48 ENSDART00000182888
pleca
plectin a
chr6_-_56103718 1.46 ENSDART00000191002
gcnt7
glucosaminyl (N-acetyl) transferase family member 7
chr8_+_7144066 1.43 ENSDART00000146306
slc6a6a
solute carrier family 6 (neurotransmitter transporter), member 6a
chr25_+_16098620 1.43 ENSDART00000142564
ENSDART00000165598
far1
fatty acyl CoA reductase 1
chr2_-_5475910 1.39 ENSDART00000100954
ENSDART00000172143
ENSDART00000132496
proca
proca
protein C (inactivator of coagulation factors Va and VIIIa), a
protein C (inactivator of coagulation factors Va and VIIIa), a
chr13_-_40726865 1.37 ENSDART00000099847
st3gal7
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr21_+_21803363 1.34 ENSDART00000081184
neu3.3
sialidase 3 (membrane sialidase), tandem duplicate 3
chr21_+_21803596 1.32 ENSDART00000084600
ENSDART00000184899
neu3.3
sialidase 3 (membrane sialidase), tandem duplicate 3
chr5_+_13385837 1.30 ENSDART00000191190
ccl19a.1
chemokine (C-C motif) ligand 19a, tandem duplicate 1
chr1_-_21409877 1.30 ENSDART00000102782
gria2a
glutamate receptor, ionotropic, AMPA 2a
chr11_-_40647190 1.27 ENSDART00000173217
ENSDART00000173276
ENSDART00000147264
fam213b
family with sequence similarity 213, member B
chr21_-_3613702 1.24 ENSDART00000139194
dym
dymeclin
chr18_-_25905574 1.19 ENSDART00000143899
ENSDART00000163369
sema4ba
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ba
chr12_-_20373058 1.18 ENSDART00000066382
aqp8a.1
aquaporin 8a, tandem duplicate 1
chr14_+_8504410 1.16 ENSDART00000123364
vegfba
vascular endothelial growth factor Ba
chr18_+_9382847 1.16 ENSDART00000061886
sema3ab
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr4_+_34119824 1.15 ENSDART00000165637
si:ch211-223g7.6
si:ch211-223g7.6
chr24_-_31123365 1.13 ENSDART00000182947
tmem56a
transmembrane protein 56a
chr23_+_26491931 1.12 ENSDART00000190124
ENSDART00000132905
si:ch73-206d17.1
si:ch73-206d17.1
chr16_-_18702249 1.06 ENSDART00000191595
fhod3b
formin homology 2 domain containing 3b
chr6_+_13606410 1.05 ENSDART00000104716
asic4b
acid-sensing (proton-gated) ion channel family member 4b
chr9_-_34269066 1.04 ENSDART00000059955
ildr1b
immunoglobulin-like domain containing receptor 1b
chr9_+_30720048 1.04 ENSDART00000146115
klf12b
Kruppel-like factor 12b
chr5_+_9348284 1.03 ENSDART00000149417
tal2
T-cell acute lymphocytic leukemia 2
chr23_-_24394719 1.03 ENSDART00000044918
epha2b
eph receptor A2 b
chr5_-_29488245 1.01 ENSDART00000047719
ENSDART00000141154
ENSDART00000171165
cacna1ba
calcium channel, voltage-dependent, N type, alpha 1B subunit, a
chr2_-_5466708 1.01 ENSDART00000136682
proca
protein C (inactivator of coagulation factors Va and VIIIa), a
chr13_-_23666579 0.98 ENSDART00000192457
ENSDART00000179777
map3k21
mitogen-activated protein kinase kinase kinase 21
chr4_-_56954002 0.98 ENSDART00000160934
si:dkey-269o24.1
si:dkey-269o24.1
chr3_+_12718100 0.95 ENSDART00000162343
ENSDART00000192425
cyp2k20
cytochrome P450, family 2, subfamily k, polypeptide 20
chr17_-_44440832 0.94 ENSDART00000148786
exoc5
exocyst complex component 5
chr17_-_47305034 0.93 ENSDART00000150116
alk
ALK receptor tyrosine kinase
chr15_+_40079468 0.93 ENSDART00000154947
ngef
neuronal guanine nucleotide exchange factor
chr24_-_3304664 0.93 ENSDART00000183168
sugct
succinyl-CoA:glutarate-CoA transferase
chr6_+_20647155 0.92 ENSDART00000193477
slc19a1
solute carrier family 19 (folate transporter), member 1
chr17_+_1496107 0.92 ENSDART00000187804
LO018430.1

chr13_+_2394264 0.91 ENSDART00000168595
elovl5
ELOVL fatty acid elongase 5
chr3_+_15505275 0.90 ENSDART00000141714
nupr1
nuclear protein 1
chr20_+_6543674 0.90 ENSDART00000134204
tns3.1
tensin 3, tandem duplicate 1
chr6_-_18250857 0.87 ENSDART00000159486
anapc11
APC11 anaphase promoting complex subunit 11 homolog (yeast)
chr3_+_40170216 0.85 ENSDART00000011568
syngr3a
synaptogyrin 3a
chr11_-_27962757 0.84 ENSDART00000147386
ece1
endothelin converting enzyme 1
chr9_+_29994439 0.83 ENSDART00000012447
tmem30c
transmembrane protein 30C
chr22_-_23781083 0.83 ENSDART00000166563
ENSDART00000170458
ENSDART00000166158
ENSDART00000171246
cfhl3
complement factor H like 3
chr8_-_18535822 0.82 ENSDART00000100558
nexn
nexilin (F actin binding protein)
chr20_-_25436389 0.82 ENSDART00000153266
itsn2a
intersectin 2a
chr17_+_15033822 0.79 ENSDART00000154987
samd4a
sterile alpha motif domain containing 4A
chr3_-_34084387 0.78 ENSDART00000155365
ighv4-3
immunoglobulin heavy variable 4-3
chr21_+_37442458 0.77 ENSDART00000180161
ENSDART00000186950
cox7b
cytochrome c oxidase subunit VIIb
chr24_-_20016817 0.77 ENSDART00000082201
ENSDART00000189448
slc22a13b
solute carrier family 22 member 13b
chr13_+_48617974 0.74 ENSDART00000168596
si:ch1073-268j14.1
si:ch1073-268j14.1
chr3_-_18047150 0.73 ENSDART00000020376
hsd17b1
hydroxysteroid (17-beta) dehydrogenase 1
chr8_-_47800754 0.71 ENSDART00000115050
ENSDART00000133669
kank3
KN motif and ankyrin repeat domains 3
chr14_+_740032 0.70 ENSDART00000165014
klb
klotho beta
chr20_+_10544100 0.68 ENSDART00000113927
serpina1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr18_-_5111449 0.68 ENSDART00000046902
pdcd10a
programmed cell death 10a
chr21_+_43669943 0.68 ENSDART00000136025
tmlhe
trimethyllysine hydroxylase, epsilon
chr7_-_29625509 0.67 ENSDART00000173723
rorab
RAR-related orphan receptor A, paralog b
chr14_-_41556533 0.61 ENSDART00000074401
itga6l
integrin, alpha 6, like
chr10_+_20108557 0.59 ENSDART00000142708
dmtn
dematin actin binding protein
chr25_+_23280220 0.56 ENSDART00000153940
ptprjb.1
protein tyrosine phosphatase, receptor type, Jb, tandem duplicate 1
chr22_-_23706771 0.53 ENSDART00000159771
cfhl1
complement factor H like 1
chr14_+_23874062 0.51 ENSDART00000172149
sh3rf2
SH3 domain containing ring finger 2
chr7_-_61901695 0.49 ENSDART00000110328
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr2_-_44746723 0.48 ENSDART00000041806
acsm3
acyl-CoA synthetase medium chain family member 3
chr5_+_45322734 0.47 ENSDART00000084411
adamts3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr2_-_43635777 0.45 ENSDART00000148633
itgb1b.1
integrin, beta 1b.1
chr2_-_48396061 0.43 ENSDART00000161657
si:ch211-195j11.30
si:ch211-195j11.30
chr11_-_19501439 0.39 ENSDART00000158328
ENSDART00000103983
slc2a9l1
solute carrier family 2 (facilitated glucose transporter), member 9-like 1
chr6_-_49078702 0.39 ENSDART00000135185
slc5a8l
solute carrier family 5 (iodide transporter), member 8-like
chr17_+_30591287 0.38 ENSDART00000154243
si:dkey-190l8.2
si:dkey-190l8.2
chr6_-_37744430 0.37 ENSDART00000150177
ENSDART00000149722
nipa2
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr3_-_6191950 0.34 ENSDART00000161931
si:ch73-144l3.1
si:ch73-144l3.1
chr4_-_32642681 0.34 ENSDART00000188695
ENSDART00000193974
si:dkey-265e7.1
si:dkey-265e7.1
chr20_+_18740799 0.34 ENSDART00000174532
fam167ab
family with sequence similarity 167, member Ab
chr18_+_13182528 0.33 ENSDART00000166298
zgc:56622
zgc:56622
chr23_+_25856541 0.33 ENSDART00000145426
ENSDART00000028236
hnf4a
hepatocyte nuclear factor 4, alpha
chr20_-_7293837 0.32 ENSDART00000100060
dsc2l
desmocollin 2 like
chr22_-_36750589 0.32 ENSDART00000010824
acy1
aminoacylase 1
chr21_-_38853737 0.30 ENSDART00000184100
tlr22
toll-like receptor 22
chr16_+_4138331 0.30 ENSDART00000192403
ENSDART00000193036
mtf1
metal-regulatory transcription factor 1
chr8_-_13013123 0.29 ENSDART00000147802
dennd2da
DENN/MADD domain containing 2Da
chr2_-_24402341 0.29 ENSDART00000155442
ENSDART00000088572
zgc:154006
zgc:154006
chr22_+_12770877 0.28 ENSDART00000044683
ftcd
formimidoyltransferase cyclodeaminase
chr9_-_43538328 0.26 ENSDART00000140526
znf385b
zinc finger protein 385B
chr13_+_38430466 0.25 ENSDART00000132691
adgrb3
adhesion G protein-coupled receptor B3
chr24_+_14713776 0.25 ENSDART00000134475
gdap1
ganglioside induced differentiation associated protein 1
chr25_+_16194979 0.24 ENSDART00000185592
ENSDART00000158582
ENSDART00000161109
ENSDART00000139013
mical2b
microtubule associated monooxygenase, calponin and LIM domain containing 2b
chr14_-_11507211 0.24 ENSDART00000186873
ENSDART00000109181
ENSDART00000186166
ENSDART00000186986
zgc:174917
zgc:174917
chr11_-_13341483 0.23 ENSDART00000164978
mast3b
microtubule associated serine/threonine kinase 3b
chr15_+_9297340 0.23 ENSDART00000055554
slc37a4a
solute carrier family 37 (glucose-6-phosphate transporter), member 4a
chr4_+_2620751 0.16 ENSDART00000013924
gpr22a
G protein-coupled receptor 22a
chr6_+_28140816 0.16 ENSDART00000137907
inpp5d
inositol polyphosphate-5-phosphatase D
chr2_-_10943093 0.16 ENSDART00000148999
ssbp3a
single stranded DNA binding protein 3a
chr15_-_17869115 0.15 ENSDART00000112838
atf5b
activating transcription factor 5b
chr11_-_12801157 0.13 ENSDART00000103449
txlng
taxilin gamma
chr4_+_45484774 0.11 ENSDART00000150573
si:dkey-256i11.6
si:dkey-256i11.6
chr11_-_12800945 0.11 ENSDART00000191178
txlng
taxilin gamma
chr21_+_11535304 0.08 ENSDART00000158901
ENSDART00000081600
cd8b
cd8 beta

Network of associatons between targets according to the STRING database.

First level regulatory network of hnf1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.0 GO:0030299 intestinal cholesterol absorption(GO:0030299)
1.2 3.5 GO:0033210 leptin-mediated signaling pathway(GO:0033210) cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.6 8.0 GO:0016556 mRNA modification(GO:0016556)
0.5 1.5 GO:0006824 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.5 11.7 GO:0015701 bicarbonate transport(GO:0015701)
0.5 2.0 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.5 5.0 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.4 2.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.4 3.3 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.4 5.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.4 10.3 GO:0051180 vitamin transport(GO:0051180)
0.3 29.4 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.3 1.9 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.3 2.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.3 4.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.3 1.8 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.2 2.6 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.2 1.9 GO:0031179 peptide modification(GO:0031179)
0.2 1.2 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.2 1.6 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.2 0.7 GO:1903358 regulation of Golgi organization(GO:1903358)
0.2 2.7 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.2 2.4 GO:0046386 deoxyribonucleotide catabolic process(GO:0009264) deoxyribose phosphate catabolic process(GO:0046386)
0.2 2.9 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.2 18.6 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.2 2.5 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.2 3.0 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 3.1 GO:0001556 oocyte maturation(GO:0001556)
0.1 2.8 GO:0032438 melanosome organization(GO:0032438)
0.1 1.5 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 1.2 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.7 GO:0008210 estrogen biosynthetic process(GO:0006703) estrogen metabolic process(GO:0008210)
0.1 2.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.3 GO:0019557 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 2.0 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 1.3 GO:0048899 anterior lateral line development(GO:0048899)
0.1 3.0 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.3 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.1 1.5 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 0.9 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 0.8 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.3 GO:0002159 desmosome assembly(GO:0002159)
0.1 1.4 GO:0072348 sulfur compound transport(GO:0072348)
0.1 2.3 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.1 1.0 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.1 2.5 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 2.2 GO:0030261 chromosome condensation(GO:0030261)
0.1 0.3 GO:0016322 neuron remodeling(GO:0016322)
0.0 1.1 GO:0051639 actin filament network formation(GO:0051639)
0.0 1.0 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 3.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 1.9 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 1.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.9 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.9 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 4.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 1.3 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 1.0 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 0.6 GO:0048844 artery morphogenesis(GO:0048844)
0.0 1.5 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 2.4 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.3 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 1.7 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 1.2 GO:0007596 blood coagulation(GO:0007596)
0.0 3.0 GO:0006814 sodium ion transport(GO:0006814)
0.0 3.1 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.8 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 1.6 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 18.0 GO:0006508 proteolysis(GO:0006508)
0.0 0.2 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.5 GO:0046328 regulation of JNK cascade(GO:0046328)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 10.3 GO:0045095 keratin filament(GO:0045095)
0.4 5.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.3 2.2 GO:0000796 condensin complex(GO:0000796)
0.2 0.7 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.1 2.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 5.0 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 3.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 1.5 GO:0030056 hemidesmosome(GO:0030056)
0.1 3.3 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 6.0 GO:0005604 basement membrane(GO:0005604)
0.1 7.6 GO:0016324 apical plasma membrane(GO:0016324)
0.1 0.8 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.9 GO:0008305 integrin complex(GO:0008305)
0.0 0.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 48.3 GO:0005615 extracellular space(GO:0005615)
0.0 3.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.9 GO:0000145 exocyst(GO:0000145)
0.0 1.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 7.5 GO:0043235 receptor complex(GO:0043235)
0.0 2.2 GO:0005795 Golgi stack(GO:0005795)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.1 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 5.6 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.8 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 13.8 GO:0005887 integral component of plasma membrane(GO:0005887)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.7 GO:0005499 vitamin D binding(GO:0005499)
0.8 5.0 GO:0017040 ceramidase activity(GO:0017040)
0.8 3.3 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.8 2.5 GO:0030251 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.7 13.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.7 4.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.6 32.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.5 3.1 GO:0019215 intermediate filament binding(GO:0019215)
0.5 2.5 GO:0032052 bile acid binding(GO:0032052)
0.5 6.0 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.5 1.4 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.4 1.7 GO:0005463 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.4 1.7 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.4 10.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 1.5 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.3 0.9 GO:0043621 protein self-association(GO:0043621)
0.3 0.9 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.3 29.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 2.7 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.2 2.2 GO:0004046 aminoacylase activity(GO:0004046)
0.2 6.1 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 1.9 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.2 1.4 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.2 1.5 GO:0031419 cobalamin binding(GO:0031419)
0.2 0.7 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.2 2.9 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.2 2.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.3 GO:0005542 folic acid binding(GO:0005542)
0.1 2.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 10.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 2.4 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 1.2 GO:0015250 water channel activity(GO:0015250)
0.1 3.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.9 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 1.6 GO:0005504 fatty acid binding(GO:0005504)
0.1 8.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 1.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 1.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 3.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.5 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 4.6 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 0.4 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1 3.5 GO:0017046 peptide hormone binding(GO:0017046)
0.1 0.5 GO:0098639 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 1.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 1.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 2.0 GO:0015248 sterol transporter activity(GO:0015248)
0.1 16.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.4 GO:1901682 sulfur compound transmembrane transporter activity(GO:1901682)
0.1 4.7 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.1 0.3 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 1.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.7 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 8.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.9 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.9 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0 0.5 GO:0016408 C-acyltransferase activity(GO:0016408)
0.0 0.8 GO:0030371 translation repressor activity(GO:0030371)
0.0 3.0 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 1.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 2.9 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.8 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 5.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 1.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 PID IL27 PATHWAY IL27-mediated signaling events
0.1 2.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 3.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 3.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 1.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 4.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID FGF PATHWAY FGF signaling pathway
0.0 0.8 PID INSULIN PATHWAY Insulin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.4 10.4 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.3 1.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 3.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 3.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 5.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.2 0.9 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 3.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 1.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 2.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 5.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 3.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 3.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.9 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.7 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 5.6 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 0.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors