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PRJEB1986: zebrafish developmental stages transcriptome

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Results for hnf1ba+hnf1bb

Z-value: 1.65

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Transcription factors associated with hnf1ba+hnf1bb

Gene Symbol Gene ID Gene Info
hnf1ba
ENSDARG00000006615 HNF1 homeobox Ba
hnf1bb
ENSDARG00000022295 HNF1 homeobox Bb
hnf1ba
ENSDARG00000115522 HNF1 homeobox Ba

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hnf1bbdr11_v1_chr21_+_38817785_388178430.662.2e-03Click!
hnf1badr11_v1_chr15_-_16012963_160129630.312.0e-01Click!

Activity profile of hnf1ba+hnf1bb motif

Sorted Z-values of hnf1ba+hnf1bb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_17159761 6.48 ENSDART00000080449
slc5a1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr5_-_30620625 6.42 ENSDART00000098273
tcnl
transcobalamin like
chr7_-_35066457 6.27 ENSDART00000058067
zgc:112160
zgc:112160
chr24_-_4765740 6.01 ENSDART00000121576
cpb1
carboxypeptidase B1 (tissue)
chr5_+_45677781 5.18 ENSDART00000163120
ENSDART00000126537
gc
group-specific component (vitamin D binding protein)
chr20_-_40750953 4.47 ENSDART00000061256
cx28.9
connexin 28.9
chr20_-_40754794 3.94 ENSDART00000187251
cx32.3
connexin 32.3
chr10_+_25726694 3.62 ENSDART00000140308
ugt5d1
UDP glucuronosyltransferase 5 family, polypeptide D1
chr6_+_30456788 3.59 ENSDART00000121492
FP236735.1

chr7_-_29534001 3.45 ENSDART00000124028
anxa2b
annexin A2b
chr4_+_18804317 3.30 ENSDART00000101043
slc26a3.2
solute carrier family 26 (anion exchanger), member 3, tandem duplicate 2
chr6_+_60055168 3.25 ENSDART00000008752
pck1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr2_-_41942666 3.13 ENSDART00000075673
ebi3
Epstein-Barr virus induced 3
chr3_-_16760923 3.10 ENSDART00000055855
aspdh
aspartate dehydrogenase domain containing
chr5_+_28848870 2.67 ENSDART00000149563
zgc:174259
zgc:174259
chr14_+_31721171 2.33 ENSDART00000173034
adgrg4a
adhesion G protein-coupled receptor G4a
chr5_+_28830388 2.27 ENSDART00000149150
serpina7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr5_+_28849155 2.25 ENSDART00000079090
zgc:174259
zgc:174259
chr1_-_12126535 2.21 ENSDART00000164817
ENSDART00000015251
mttp
microsomal triglyceride transfer protein
chr5_+_28830643 2.15 ENSDART00000051448
serpina7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr20_-_40755614 2.10 ENSDART00000061247
cx32.3
connexin 32.3
chr6_+_38381957 2.08 ENSDART00000087300
gabrb3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr8_+_46418996 1.93 ENSDART00000144285
si:ch211-196g2.4
si:ch211-196g2.4
chr12_-_6177894 1.93 ENSDART00000152292
a1cf
apobec1 complementation factor
chr4_+_7827261 1.87 ENSDART00000129568
phyh
phytanoyl-CoA 2-hydroxylase
chr5_-_65158203 1.79 ENSDART00000171656
sh2d3cb
SH2 domain containing 3Cb
chr5_+_29851433 1.78 ENSDART00000143434
ubash3ba
ubiquitin associated and SH3 domain containing Ba
chr11_-_37997419 1.75 ENSDART00000102870
slc41a1
solute carrier family 41 (magnesium transporter), member 1
chr14_+_2487672 1.74 ENSDART00000170629
ENSDART00000123063
fgf18a
fibroblast growth factor 18a
chr4_-_9533345 1.72 ENSDART00000128501
si:ch73-139j3.4
si:ch73-139j3.4
chr10_+_21867307 1.62 ENSDART00000126629
cbln17
cerebellin 17
chr21_+_38002879 1.57 ENSDART00000065183
cldn2
claudin 2
chr8_+_50742975 1.54 ENSDART00000155664
ENSDART00000160612
si:ch73-6l19.2
si:ch73-6l19.2
chr20_+_10538025 1.51 ENSDART00000129762
serpina1l
serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like
chr6_+_41039166 1.44 ENSDART00000125659
entpd8
ectonucleoside triphosphate diphosphohydrolase 8
chr18_-_25905574 1.44 ENSDART00000143899
ENSDART00000163369
sema4ba
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ba
chr20_+_51006362 1.43 ENSDART00000028084
mpp5b
membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5)
chr5_+_4054704 1.43 ENSDART00000140537
dhrs11a
dehydrogenase/reductase (SDR family) member 11a
chr16_+_26777473 1.37 ENSDART00000188870
cdh17
cadherin 17, LI cadherin (liver-intestine)
chr6_-_59563597 1.36 ENSDART00000166311
INHBE
inhibin beta E subunit
chr6_-_25180438 1.36 ENSDART00000159696
lrrc8db
leucine rich repeat containing 8 VRAC subunit Db
chr4_-_5317006 1.35 ENSDART00000150867
si:ch211-214j24.15
si:ch211-214j24.15
chr25_-_35497055 1.33 ENSDART00000009271
slc5a12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr13_+_23988442 1.32 ENSDART00000010918
agt
angiotensinogen
chr5_+_28858345 1.30 ENSDART00000111180
si:ch211-186e20.2
si:ch211-186e20.2
chr1_-_19502322 1.29 ENSDART00000181888
ENSDART00000044030
kitb
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr3_+_26734162 1.27 ENSDART00000114552
si:dkey-202l16.5
si:dkey-202l16.5
chr5_-_37886063 1.25 ENSDART00000131378
ENSDART00000132152
si:ch211-139a5.9
si:ch211-139a5.9
chr16_-_22294265 1.24 ENSDART00000124718
aqp10a
aquaporin 10a
chr7_-_4296771 1.21 ENSDART00000128855
cbln11
cerebellin 11
chr5_+_37854685 1.18 ENSDART00000051222
ENSDART00000185283
ins
preproinsulin
chr4_-_12766418 1.17 ENSDART00000024312
dera
deoxyribose-phosphate aldolase (putative)
chr4_-_34480599 1.16 ENSDART00000159602
ENSDART00000182248
si:dkeyp-51g9.4
si:ch211-64i20.3
si:dkeyp-51g9.4
si:ch211-64i20.3
chr11_-_40647190 1.13 ENSDART00000173217
ENSDART00000173276
ENSDART00000147264
fam213b
family with sequence similarity 213, member B
chr19_-_22568203 1.11 ENSDART00000182888
pleca
plectin a
chr2_+_1486822 1.10 ENSDART00000132500
c8a
complement component 8, alpha polypeptide
chr8_-_53490376 1.06 ENSDART00000158789
chdh
choline dehydrogenase
chr21_+_39100289 1.04 ENSDART00000075958
slc13a2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr24_-_39610585 1.03 ENSDART00000066506
cox6b1
cytochrome c oxidase subunit VIb polypeptide 1
chr16_+_11603096 1.03 ENSDART00000146286
si:dkey-11o1.3
si:dkey-11o1.3
chr1_+_34224360 1.02 ENSDART00000192938
arl6
ADP-ribosylation factor-like 6
chr20_+_23440632 1.01 ENSDART00000180685
ENSDART00000042820
si:dkey-90m5.4
si:dkey-90m5.4
chr18_+_3530769 1.00 ENSDART00000163469
si:ch73-338a16.3
si:ch73-338a16.3
chr15_+_29283981 0.98 ENSDART00000099895
rap1gap2a
RAP1 GTPase activating protein 2a
chr6_+_10094061 0.96 ENSDART00000150998
ENSDART00000162236
atp7b
ATPase copper transporting beta
chr12_+_35067863 0.96 ENSDART00000152849
syt15
synaptotagmin XV
chr7_-_72277269 0.95 ENSDART00000161914
ENSDART00000183927
slc35c1
solute carrier family 35 (GDP-fucose transporter), member C1
chr25_+_4091067 0.94 ENSDART00000104926
eps8l2
EPS8 like 2
chr10_-_41664427 0.94 ENSDART00000150213
ggt1b
gamma-glutamyltransferase 1b
chr5_+_9428876 0.92 ENSDART00000081791
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr13_+_31205439 0.92 ENSDART00000132326
ptpn20
protein tyrosine phosphatase, non-receptor type 20
chr16_+_11623956 0.84 ENSDART00000137788
cxcr3.1
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr14_+_32430982 0.84 ENSDART00000017179
ENSDART00000123382
ENSDART00000075593
f9a
coagulation factor IXa
chr6_+_13606410 0.84 ENSDART00000104716
asic4b
acid-sensing (proton-gated) ion channel family member 4b
chr5_-_12063381 0.80 ENSDART00000026749
nipsnap1
nipsnap homolog 1 (C. elegans)
chr10_+_25369859 0.77 ENSDART00000047541
bach1b
BTB and CNC homology 1, basic leucine zipper transcription factor 1 b
chr2_+_1487118 0.77 ENSDART00000147283
c8a
complement component 8, alpha polypeptide
chr6_-_56103718 0.77 ENSDART00000191002
gcnt7
glucosaminyl (N-acetyl) transferase family member 7
chr22_+_16555939 0.74 ENSDART00000012604
pdzk1ip1
PDZK1 interacting protein 1
chr23_+_26491931 0.72 ENSDART00000190124
ENSDART00000132905
si:ch73-206d17.1
si:ch73-206d17.1
chr2_-_5466708 0.72 ENSDART00000136682
proca
protein C (inactivator of coagulation factors Va and VIIIa), a
chr23_+_27740788 0.68 ENSDART00000053871
dhh
desert hedgehog
chr12_+_5209822 0.68 ENSDART00000152610
SLC35G1
si:ch211-197g18.2
chr8_+_30699429 0.67 ENSDART00000005345
upb1
ureidopropionase, beta
chr13_+_43050562 0.67 ENSDART00000016602
cdh23
cadherin-related 23
chr2_-_5475910 0.66 ENSDART00000100954
ENSDART00000172143
ENSDART00000132496
proca
proca
protein C (inactivator of coagulation factors Va and VIIIa), a
protein C (inactivator of coagulation factors Va and VIIIa), a
chr8_-_18535822 0.66 ENSDART00000100558
nexn
nexilin (F actin binding protein)
chr9_+_30720048 0.66 ENSDART00000146115
klf12b
Kruppel-like factor 12b
chr11_+_575665 0.61 ENSDART00000122133
mkrn2os.1
MKRN2 opposite strand, tandem duplicate 1
chr16_-_18702249 0.61 ENSDART00000191595
fhod3b
formin homology 2 domain containing 3b
chr15_+_25156382 0.60 ENSDART00000171092
slc35f2l
info solute carrier family 35, member F2, like
chr25_+_23280220 0.59 ENSDART00000153940
ptprjb.1
protein tyrosine phosphatase, receptor type, Jb, tandem duplicate 1
chr13_-_18835254 0.59 ENSDART00000147579
ENSDART00000146795
lzts2a
leucine zipper, putative tumor suppressor 2a
chr18_+_14342326 0.58 ENSDART00000181013
ENSDART00000138372
si:dkey-246g23.2
si:dkey-246g23.2
chr5_-_42904329 0.58 ENSDART00000112807
cxcl20
chemokine (C-X-C motif) ligand 20
chr8_+_23391263 0.57 ENSDART00000149687
si:dkey-16n15.6
si:dkey-16n15.6
chr25_+_16098620 0.55 ENSDART00000142564
ENSDART00000165598
far1
fatty acyl CoA reductase 1
chr11_-_13341051 0.55 ENSDART00000121872
mast3b
microtubule associated serine/threonine kinase 3b
chr20_+_10544100 0.54 ENSDART00000113927
serpina1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr17_-_51893123 0.54 ENSDART00000103350
ENSDART00000017329
numb
numb homolog (Drosophila)
chr5_+_45322734 0.53 ENSDART00000084411
adamts3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr4_+_34119824 0.52 ENSDART00000165637
si:ch211-223g7.6
si:ch211-223g7.6
chr17_+_15033822 0.49 ENSDART00000154987
samd4a
sterile alpha motif domain containing 4A
chr17_-_50233493 0.49 ENSDART00000172266
fosaa
v-fos FBJ murine osteosarcoma viral oncogene homolog Aa
chr14_+_740032 0.48 ENSDART00000165014
klb
klotho beta
chr3_+_19446997 0.47 ENSDART00000079352
zgc:123297
zgc:123297
chr5_+_13385837 0.47 ENSDART00000191190
ccl19a.1
chemokine (C-C motif) ligand 19a, tandem duplicate 1
chr22_+_26665422 0.45 ENSDART00000164994
adcy9
adenylate cyclase 9
chr8_-_47800754 0.44 ENSDART00000115050
ENSDART00000133669
kank3
KN motif and ankyrin repeat domains 3
chr23_+_27740592 0.43 ENSDART00000137875
dhh
desert hedgehog
chr23_+_39346774 0.43 ENSDART00000190985
src
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr13_-_23666579 0.42 ENSDART00000192457
ENSDART00000179777
map3k21
mitogen-activated protein kinase kinase kinase 21
chr4_-_56954002 0.42 ENSDART00000160934
si:dkey-269o24.1
si:dkey-269o24.1
chr24_-_31123365 0.42 ENSDART00000182947
tmem56a
transmembrane protein 56a
chr8_+_23390844 0.40 ENSDART00000184556
si:dkey-16n15.6
si:dkey-16n15.6
chr9_+_29994439 0.40 ENSDART00000012447
tmem30c
transmembrane protein 30C
chr11_-_19501439 0.40 ENSDART00000158328
ENSDART00000103983
slc2a9l1
solute carrier family 2 (facilitated glucose transporter), member 9-like 1
chr22_-_23706771 0.39 ENSDART00000159771
cfhl1
complement factor H like 1
chr12_-_17152139 0.38 ENSDART00000152478
stambpl1
STAM binding protein-like 1
chr1_+_45085194 0.38 ENSDART00000193863
si:ch211-151p13.8
si:ch211-151p13.8
chr17_-_17948587 0.37 ENSDART00000090447
hhipl1
HHIP-like 1
chr13_-_40726865 0.35 ENSDART00000099847
st3gal7
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr21_+_43669943 0.34 ENSDART00000136025
tmlhe
trimethyllysine hydroxylase, epsilon
chr4_-_32642681 0.33 ENSDART00000188695
ENSDART00000193974
si:dkey-265e7.1
si:dkey-265e7.1
chr4_-_73136420 0.33 ENSDART00000160907
si:ch73-170d6.3
si:ch73-170d6.3
chr11_-_575786 0.32 ENSDART00000019997
mkrn2
makorin, ring finger protein, 2
chr3_-_34084387 0.31 ENSDART00000155365
ighv4-3
immunoglobulin heavy variable 4-3
chr12_-_3940768 0.29 ENSDART00000134292
zgc:92040
zgc:92040
chr1_+_12178215 0.29 ENSDART00000090380
stra6l
STRA6-like
chr23_+_25856541 0.29 ENSDART00000145426
ENSDART00000028236
hnf4a
hepatocyte nuclear factor 4, alpha
chr20_+_31076488 0.29 ENSDART00000136255
ENSDART00000008840
otofa
otoferlin a
chr8_+_26293673 0.26 ENSDART00000144977
mgll
monoglyceride lipase
chr23_+_39346930 0.25 ENSDART00000102843
src
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr6_-_43027828 0.24 ENSDART00000149637
glyctk
glycerate kinase
chr5_-_67661102 0.24 ENSDART00000013605
zbtb20
zinc finger and BTB domain containing 20
chr11_-_45152912 0.22 ENSDART00000167540
ENSDART00000173050
ENSDART00000170795
afmid
arylformamidase
chr7_+_34602991 0.21 ENSDART00000073447
fhod1
formin homology 2 domain containing 1
chr21_+_39941559 0.20 ENSDART00000189718
ENSDART00000160875
ENSDART00000135235
slc47a1
solute carrier family 47 (multidrug and toxin extrusion), member 1
chr15_+_28202170 0.19 ENSDART00000077736
vtna
vitronectin a
chr24_+_14713776 0.19 ENSDART00000134475
gdap1
ganglioside induced differentiation associated protein 1
chr3_+_40170216 0.18 ENSDART00000011568
syngr3a
synaptogyrin 3a
chr5_+_44846434 0.17 ENSDART00000145299
ENSDART00000136521
kank1a
KN motif and ankyrin repeat domains 1a
chr7_+_27317174 0.17 ENSDART00000193058
sox6
SRY (sex determining region Y)-box 6
chr5_+_60919378 0.16 ENSDART00000184915
doc2b
double C2-like domains, beta
chr24_-_17039638 0.16 ENSDART00000048823
c8g
complement component 8, gamma polypeptide
chr6_-_29515709 0.15 ENSDART00000180205
pex5la
peroxisomal biogenesis factor 5-like a
chr2_+_26647472 0.15 ENSDART00000145415
ENSDART00000157409
ttpa
tocopherol (alpha) transfer protein
chr11_-_45152702 0.14 ENSDART00000168066
afmid
arylformamidase
chr17_-_47305034 0.14 ENSDART00000150116
alk
ALK receptor tyrosine kinase
chr21_-_38853737 0.14 ENSDART00000184100
tlr22
toll-like receptor 22
chr17_+_5895500 0.14 ENSDART00000019905
fndc4b
fibronectin type III domain containing 4b
chr6_-_43028270 0.13 ENSDART00000149092
ENSDART00000149559
glyctk
glycerate kinase
chr19_-_15229421 0.12 ENSDART00000055619
phactr4a
phosphatase and actin regulator 4a
chr8_+_26329482 0.12 ENSDART00000048676
prkar2aa
protein kinase, cAMP-dependent, regulatory, type II, alpha A
chr23_+_28770225 0.12 ENSDART00000132179
ENSDART00000142273
masp2
mannan-binding lectin serine peptidase 2
chr18_-_48508585 0.12 ENSDART00000133364
kcnj1a.4
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 4
chr24_+_25913162 0.12 ENSDART00000143099
ENSDART00000184814
map3k15
mitogen-activated protein kinase kinase kinase 15
chr6_+_28140816 0.11 ENSDART00000137907
inpp5d
inositol polyphosphate-5-phosphatase D
chr19_+_8144556 0.10 ENSDART00000027274
ENSDART00000147218
efna3a
ephrin-A3a
chr21_+_39941184 0.10 ENSDART00000133604
slc47a1
solute carrier family 47 (multidrug and toxin extrusion), member 1
chr22_-_23781083 0.09 ENSDART00000166563
ENSDART00000170458
ENSDART00000166158
ENSDART00000171246
cfhl3
complement factor H like 3
chr24_-_6078222 0.08 ENSDART00000146830
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr11_-_13341483 0.07 ENSDART00000164978
mast3b
microtubule associated serine/threonine kinase 3b
chr18_+_13182528 0.06 ENSDART00000166298
zgc:56622
zgc:56622
chr25_+_13406069 0.06 ENSDART00000010495
znrf1
zinc and ring finger 1
chr2_+_36121373 0.05 ENSDART00000187002
CT867973.2

chr7_-_59564011 0.03 ENSDART00000186053
zgc:112271
zgc:112271
chr6_-_49078702 0.02 ENSDART00000135185
slc5a8l
solute carrier family 5 (iodide transporter), member 8-like
chr2_-_43635777 0.01 ENSDART00000148633
itgb1b.1
integrin, beta 1b.1
chr7_-_27696958 0.01 ENSDART00000173470
calca
calcitonin/calcitonin-related polypeptide, alpha
chr14_+_24033718 0.00 ENSDART00000172860
si:ch211-277c7.6
si:ch211-277c7.6

Network of associatons between targets according to the STRING database.

First level regulatory network of hnf1ba+hnf1bb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0044320 leptin-mediated signaling pathway(GO:0033210) cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.8 3.2 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
0.7 3.4 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.4 1.1 GO:0019695 choline metabolic process(GO:0019695)
0.3 1.3 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.3 1.2 GO:0048521 positive regulation of epithelial cell differentiation(GO:0030858) negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.3 2.2 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.3 1.9 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.2 3.5 GO:0009435 NAD biosynthetic process(GO:0009435)
0.2 0.7 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.2 1.0 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.2 1.0 GO:0072530 purine-containing compound transmembrane transport(GO:0072530)
0.2 5.4 GO:0051180 vitamin transport(GO:0051180)
0.2 14.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.2 1.8 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.2 1.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.2 0.9 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 3.3 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.9 GO:0016556 mRNA modification(GO:0016556)
0.1 0.7 GO:0019482 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.1 0.7 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.1 0.9 GO:0031179 peptide modification(GO:0031179)
0.1 1.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 1.2 GO:0046386 deoxyribonucleotide catabolic process(GO:0009264) deoxyribose phosphate catabolic process(GO:0046386)
0.1 1.4 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.1 0.7 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 1.8 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 2.1 GO:0006958 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.1 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 1.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 6.0 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.3 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.0 0.8 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.6 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 1.6 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 7.7 GO:0006814 sodium ion transport(GO:0006814)
0.0 2.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 1.0 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 1.7 GO:0007596 blood coagulation(GO:0007596)
0.0 0.6 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.3 GO:0001964 startle response(GO:0001964)
0.0 1.0 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.4 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.3 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.6 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.5 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.2 GO:0060612 adipose tissue development(GO:0060612)
0.0 1.7 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.2 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.6 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0 0.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.1 GO:0030056 hemidesmosome(GO:0030056)
0.1 2.1 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.0 GO:0060170 ciliary membrane(GO:0060170)
0.0 2.0 GO:0016342 catenin complex(GO:0016342)
0.0 3.3 GO:0005604 basement membrane(GO:0005604)
0.0 3.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 26.6 GO:0005615 extracellular space(GO:0005615)
0.0 2.4 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 3.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.7 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 0.6 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0005499 vitamin D binding(GO:0005499)
0.9 4.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.6 2.2 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.3 1.3 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.3 1.2 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.3 3.4 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.2 6.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 1.7 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2 0.8 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 1.0 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.6 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.1 2.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.1 GO:0005113 patched binding(GO:0005113)
0.1 14.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.4 GO:0004061 arylformamidase activity(GO:0004061)
0.1 0.4 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.1 0.9 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 3.1 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.1 0.4 GO:0008887 glycerate kinase activity(GO:0008887)
0.1 3.2 GO:0030145 manganese ion binding(GO:0030145)
0.1 3.1 GO:0017046 peptide hormone binding(GO:0017046)
0.1 1.4 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 4.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.6 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 1.1 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.8 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 1.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 2.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.5 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 8.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.2 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.7 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 1.9 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 2.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 1.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.5 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.3 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 1.3 GO:0019955 cytokine binding(GO:0019955)
0.0 0.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.1 PID IL27 PATHWAY IL27-mediated signaling events
0.1 4.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 0.7 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 4.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.3 1.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 2.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 5.2 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.2 1.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 2.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 2.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 6.6 REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.1 0.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.5 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.1 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.9 REACTOME MRNA PROCESSING Genes involved in mRNA Processing