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PRJEB1986: zebrafish developmental stages transcriptome

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Results for hoxa11b

Z-value: 1.37

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Transcription factors associated with hoxa11b

Gene Symbol Gene ID Gene Info
ENSDARG00000007009 homeobox A11b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxa11bdr11_v1_chr16_+_20904754_209047540.854.8e-06Click!

Activity profile of hoxa11b motif

Sorted Z-values of hoxa11b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_20194876 5.26 ENSDART00000122587
D-amino-acid oxidase, tandem duplicate 1
chr18_+_619619 5.05 ENSDART00000159846
protogenin homolog a (Gallus gallus)
chr16_+_29509133 3.70 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr3_-_26183699 3.35 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
chr19_-_47571456 3.19 ENSDART00000158071
ENSDART00000165841
ribonucleotide reductase M2 polypeptide
chr20_-_29499363 3.15 ENSDART00000152889
ENSDART00000153252
ENSDART00000170972
ENSDART00000166420
ENSDART00000163079
ribonucleotide reductase M2 polypeptide
chr19_-_47571797 3.09 ENSDART00000166180
ENSDART00000168134
ribonucleotide reductase M2 polypeptide
chr9_-_48370645 2.94 ENSDART00000140185
collagen, type XXVIII, alpha 2a
chr23_-_43718067 2.91 ENSDART00000015777
ATP-binding cassette, sub-family E (OABP), member 1
chr20_-_26491567 2.89 ENSDART00000147154
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr3_-_26184018 2.83 ENSDART00000191604
si:ch211-11k18.4
chr22_-_4644484 2.75 ENSDART00000167748
fibrillin 2b
chr21_-_22357545 2.70 ENSDART00000134320
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr1_-_53468160 2.69 ENSDART00000143349
zgc:66455
chr5_-_4532516 2.65 ENSDART00000192398
cystatin 14b, tandem duplicate 1
chr18_-_14677936 2.55 ENSDART00000111995
si:dkey-238o13.4
chr13_+_36585399 2.42 ENSDART00000030211
glia maturation factor, beta
chr10_+_22775253 2.35 ENSDART00000190141
transmembrane protein 88 a
chr22_-_10158038 2.33 ENSDART00000047444
RanBP-type and C3HC4-type zinc finger containing 1
chr10_-_13116337 2.29 ENSDART00000164568
muscle, skeletal, receptor tyrosine kinase
chr21_-_19918286 2.27 ENSDART00000180816
protein phosphatase 1, regulatory subunit 3B
chr18_+_26422124 2.26 ENSDART00000060245
cathepsin H
chr22_+_9917007 2.25 ENSDART00000063318
bloody fingers
chr19_-_14191592 2.21 ENSDART00000164594
T-box transcription factor Ta
chr2_-_44777592 2.13 ENSDART00000113351
ENSDART00000169310
non-SMC condensin I complex, subunit D2
chr8_+_12951155 2.11 ENSDART00000081601
choline/ethanolamine phosphotransferase 1a
chr2_-_26596794 2.10 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr8_-_39822917 2.09 ENSDART00000067843
zgc:162025
chr18_-_33979693 2.08 ENSDART00000021215
si:ch211-203b20.7
chr3_-_15999501 2.06 ENSDART00000160668
NME/NM23 nucleoside diphosphate kinase 3
chr7_+_34290051 2.05 ENSDART00000123498
fin bud initiation factor b
chr23_-_23401305 2.04 ENSDART00000078936
hairy-related 9
chr7_+_32695954 2.03 ENSDART00000184425
solute carrier family 39 (zinc transporter), member 13
chr2_+_58841181 2.03 ENSDART00000164102
cold inducible RNA binding protein a
chr8_+_23355484 2.03 ENSDART00000085361
ENSDART00000125729
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a
chr6_-_42388608 2.02 ENSDART00000049425
Sec61 translocon alpha 1 subunit, like
chr16_-_45917322 1.99 ENSDART00000060822
antifreeze protein type IV
chr19_-_18418763 1.99 ENSDART00000167271
zgc:112966
chr9_+_20853894 1.95 ENSDART00000003648
WD repeat domain 3
chr21_-_20328375 1.91 ENSDART00000079593
solute carrier family 26 (anion exchanger), member 1
chr8_-_32805214 1.91 ENSDART00000131597
zgc:194839
chr15_+_30323491 1.90 ENSDART00000048847
nitric oxide synthase 2b, inducible
chr17_-_31611692 1.89 ENSDART00000141480
si:dkey-170l10.1
chr8_+_12118097 1.86 ENSDART00000081819
endonuclease G
chr22_-_10440688 1.82 ENSDART00000111962
nucleolar protein 8
chr23_+_43718115 1.82 ENSDART00000149266
ENSDART00000149503
anaphase promoting complex subunit 10
chr5_+_23136544 1.78 ENSDART00000003428
ENSDART00000109340
ENSDART00000171039
ENSDART00000178821
phosphoribosyl pyrophosphate synthetase 1A
chr11_-_6877973 1.74 ENSDART00000160271
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr2_+_16482338 1.73 ENSDART00000143912
F-box protein 36b
chr1_-_20068155 1.72 ENSDART00000102993
methyltransferase like 14
chr11_+_6116503 1.71 ENSDART00000176170
nuclear receptor subfamily 2, group F, member 6b
chr2_+_20406399 1.71 ENSDART00000006817
ENSDART00000137848
palmdelphin a
chr14_+_14841685 1.69 ENSDART00000158291
ENSDART00000162039
stem-loop binding protein
chr5_-_54712159 1.69 ENSDART00000149207
cyclin B1
chr3_-_32873641 1.68 ENSDART00000075277
zgc:113090
chr19_-_27550768 1.66 ENSDART00000142313
si:dkeyp-46h3.8
chr21_+_39963851 1.64 ENSDART00000144435
solute carrier family 47 (multidrug and toxin extrusion), member 1
chr18_-_15373620 1.64 ENSDART00000031752
regulatory factor X, 4
chr18_+_26428829 1.64 ENSDART00000190779
ENSDART00000193226
ENSDART00000110746
Bloom syndrome, RecQ helicase-like
chr3_-_61387273 1.63 ENSDART00000156479
zinc finger protein 1143
chr25_-_21031007 1.61 ENSDART00000138985
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr14_+_15495088 1.60 ENSDART00000165765
ENSDART00000188577
si:dkey-203a12.6
chr15_+_23799461 1.60 ENSDART00000154885
si:ch211-167j9.4
chr17_-_18797245 1.59 ENSDART00000045991
vaccinia related kinase 1
chr22_+_21516689 1.59 ENSDART00000105550
ENSDART00000136374
mesoderm induction early response 1, family member 2
chr13_+_43400443 1.58 ENSDART00000084321
dishevelled-binding antagonist of beta-catenin 2
chr11_-_17755444 1.58 ENSDART00000154627
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr4_-_56898328 1.57 ENSDART00000169189
si:dkey-269o24.6
chr12_-_20616160 1.57 ENSDART00000105362
sorting nexin 11
chr11_-_26375575 1.54 ENSDART00000079255
UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
chr23_-_21446985 1.54 ENSDART00000044080
hairy-related 12
chr13_-_49802194 1.53 ENSDART00000148722
beta-1,3-N-acetylgalactosaminyltransferase 2
chr7_+_29163762 1.53 ENSDART00000173762
solute carrier family 38, member 8b
chr21_-_14826066 1.51 ENSDART00000067001
nucleolar complex associated 4 homolog
chr9_+_3429662 1.50 ENSDART00000160977
ENSDART00000114168
ENSDART00000082153

integrin, alpha 6a
chr16_+_38940758 1.50 ENSDART00000102482
ENSDART00000136215
enhancer of yellow 2 homolog (Drosophila)
chr20_-_25643667 1.50 ENSDART00000137457
si:dkeyp-117h8.4
chr6_+_13083146 1.49 ENSDART00000172158
trans-L-3-hydroxyproline dehydratase
chr12_+_16087077 1.49 ENSDART00000141898
zinc finger protein 281b
chr17_-_31695217 1.48 ENSDART00000104332
ENSDART00000143090
lin-52 DREAM MuvB core complex component
chr11_+_18130300 1.48 ENSDART00000169146
zgc:175135
chr10_+_25947946 1.47 ENSDART00000064393
ubiquitin-fold modifier 1
chr21_-_3007412 1.47 ENSDART00000190839
zgc:86839
chr12_+_5102670 1.47 ENSDART00000166600
centrosomal protein 55 like
chr4_+_23125689 1.46 ENSDART00000077854
MDM2 oncogene, E3 ubiquitin protein ligase
chr19_-_5699703 1.46 ENSDART00000082050
zgc:174904
chr5_-_54554583 1.46 ENSDART00000158865
ENSDART00000158069
Sjogren syndrome nuclear autoantigen 1
chr11_+_18157260 1.46 ENSDART00000144659
zgc:173545
chr2_-_10098191 1.43 ENSDART00000138081
B-cell CLL/lymphoma 6a, genome duplicate b
chr24_+_21540842 1.43 ENSDART00000091529
WAS protein family, member 3b
chr19_-_29294457 1.43 ENSDART00000130815
ENSDART00000103437
E2F transcription factor 3
chr17_+_2130018 1.42 ENSDART00000193675
ENSDART00000110529
BUB1 mitotic checkpoint serine/threonine kinase Bb
chr12_-_33817114 1.42 ENSDART00000161265
twinkle mtDNA helicase
chr9_-_52598343 1.42 ENSDART00000167922
X-ray repair complementing defective repair in Chinese hamster cells 5
chr22_-_10541372 1.41 ENSDART00000179708
si:dkey-42i9.4
chr2_+_42260021 1.41 ENSDART00000124702
ENSDART00000140203
ENSDART00000184079
ENSDART00000193349
finTRIM family, member 4
chr2_+_35595454 1.40 ENSDART00000098734
calcyclin binding protein
chr7_-_30779575 1.40 ENSDART00000004782
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr17_+_8799661 1.38 ENSDART00000105326
tonsoku-like, DNA repair protein
chr23_+_7379728 1.38 ENSDART00000012194
GATA binding protein 5
chr11_-_34783938 1.37 ENSDART00000135725
ENSDART00000039847
coiled-coil-helix-coiled-coil-helix domain containing 4a
chr2_-_10877765 1.37 ENSDART00000100607
cell division cycle 7 homolog (S. cerevisiae)
chr5_-_32396929 1.36 ENSDART00000023977
F-box and WD repeat domain containing 2
chr9_+_34952203 1.36 ENSDART00000121828
ENSDART00000142347
transcription factor Dp-1, a
chr5_-_33281046 1.36 ENSDART00000051344
ENSDART00000138116
surfeit 6
chr9_-_2892250 1.36 ENSDART00000140695
cell division cycle associated 7a
chr15_+_11814969 1.36 ENSDART00000127248

chr2_-_59145027 1.36 ENSDART00000128320

chr2_-_20715094 1.36 ENSDART00000155439
dual specificity phosphatase 12
chr4_-_32180155 1.36 ENSDART00000164151
si:dkey-72l17.6
chr17_+_17764979 1.35 ENSDART00000105013
alkB homolog 1, histone H2A dioxygenase
chr23_-_42232124 1.33 ENSDART00000149944
glutathione peroxidase 7
chr15_+_1534644 1.32 ENSDART00000130413
structural maintenance of chromosomes 4
chr8_+_15254564 1.32 ENSDART00000024433
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr1_-_44933094 1.32 ENSDART00000147527
si:dkey-9i23.14
chr10_-_25328814 1.31 ENSDART00000123820
transmembrane protein 135
chr4_+_14971239 1.31 ENSDART00000005985
smoothened, frizzled class receptor
chr21_+_13327527 1.30 ENSDART00000114294
small nuclear ribonucleoprotein D3 polypeptide, like
chr24_+_9881219 1.30 ENSDART00000036204
carnitine deficiency-associated gene expressed in ventricle 3
chr15_+_19324697 1.30 ENSDART00000022015
VPS26 retromer complex component B
chr8_-_44904723 1.29 ENSDART00000040804
PRA1 domain family, member 2
chr23_+_44349252 1.29 ENSDART00000097644
eph receptor B4b
chr21_-_17296789 1.29 ENSDART00000192180
growth factor independent 1B transcription repressor
chr8_-_32354677 1.29 ENSDART00000138268
ENSDART00000133245
ENSDART00000179677
ENSDART00000174450
importin 11
chr21_-_32781612 1.29 ENSDART00000031028
CCR4-NOT transcription complex, subunit 6a
chr8_+_23731483 1.28 ENSDART00000099751
Fanconi anemia, complementation group E
chr10_-_10864331 1.28 ENSDART00000122657
NOTCH regulated ankyrin repeat protein a
chr16_-_21903083 1.27 ENSDART00000165849
SET domain, bifurcated 1b
chr2_-_24962002 1.26 ENSDART00000132050
helicase-like transcription factor
chr13_-_11986754 1.26 ENSDART00000164214
nucleophosmin/nucleoplasmin, 3
chr13_+_2894536 1.26 ENSDART00000183678

chr22_+_2403068 1.26 ENSDART00000132925
ENSDART00000132569
zgc:112977
chr7_-_26076970 1.26 ENSDART00000101120
zgc:92664
chr5_+_69686368 1.25 ENSDART00000158237
zinc finger protein 1005
chr22_+_20145036 1.25 ENSDART00000137624
eukaryotic translation elongation factor 2a, tandem duplicate 2
chr20_-_9760424 1.25 ENSDART00000104936
si:dkey-63j12.4
chr16_-_10223741 1.25 ENSDART00000188099
si:rp71-15i12.1
chr3_+_6469754 1.24 ENSDART00000185809
nucleoporin 85
chr11_+_19603251 1.24 ENSDART00000005639
THO complex 7
chr14_-_26425416 1.23 ENSDART00000088690
lectin, mannose-binding 2
chr5_+_66433287 1.23 ENSDART00000170757
kinetochore associated 1
chr6_+_40629066 1.22 ENSDART00000103757
solute carrier family 6 (neurotransmitter transporter), member 11a
chr2_-_6065416 1.22 ENSDART00000037698
uridine-cytidine kinase 2b
chr14_+_989733 1.22 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
chr16_-_28594181 1.21 ENSDART00000059053
ribonuclease P/MRP 38 subunit
chr19_-_30447611 1.21 ENSDART00000073705
ENSDART00000048977
ENSDART00000191237
ATP-binding cassette, sub-family F (GCN20), member 1
chr6_+_58622831 1.21 ENSDART00000128793
Sp7 transcription factor
chr2_+_25839940 1.21 ENSDART00000139927
eukaryotic translation initiation factor 5A2
chr5_-_24542726 1.20 ENSDART00000182975
tRNA methyltransferase 2 homolog A
chr16_+_5908483 1.20 ENSDART00000167393
unc-51 like kinase 4
chr4_-_43280244 1.19 ENSDART00000150762
si:dkeyp-53e4.1
chr12_-_13337033 1.19 ENSDART00000105903
ENSDART00000139786
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
chr16_-_32303835 1.19 ENSDART00000191408
MMS22-like, DNA repair protein
chr23_+_11285662 1.18 ENSDART00000111028
cell adhesion molecule L1-like a
chr5_-_31856681 1.18 ENSDART00000187817
protein kinase N3
chr3_+_26244353 1.17 ENSDART00000103733
ATPase family, AAA domain containing 5a
chr9_+_21977383 1.17 ENSDART00000135032
si:dkey-57a22.11
chr2_+_20793982 1.16 ENSDART00000014785
proteoglycan 4a
chr8_+_23382568 1.16 ENSDART00000129167
microtubule-associated protein, RP/EB family, member 1a
chr6_-_54290227 1.16 ENSDART00000050483
SAM pointed domain containing ETS transcription factor
chr16_+_26777473 1.15 ENSDART00000188870
cadherin 17, LI cadherin (liver-intestine)
chr23_+_39606108 1.15 ENSDART00000109464
G0/G1 switch 2
chr8_-_25814263 1.15 ENSDART00000143397
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr24_+_18286427 1.14 ENSDART00000055443
thiamin pyrophosphokinase 1
chr8_-_17926620 1.14 ENSDART00000187864
LIM homeobox 8b
chr6_+_3693441 1.13 ENSDART00000065256
peptidylprolyl isomerase G (cyclophilin G)
chr23_+_2666944 1.13 ENSDART00000192861

chr17_-_10043273 1.12 ENSDART00000156078
bromodomain adjacent to zinc finger domain, 1A
chr23_+_10146542 1.12 ENSDART00000048073
zgc:171775
chr15_-_25527580 1.12 ENSDART00000167005
ENSDART00000157498
hypoxia-inducible factor 1, alpha subunit, like
chr22_+_2170887 1.11 ENSDART00000147881
ENSDART00000169375
ENSDART00000165871
ENSDART00000166014
zinc finger protein 1151
chr4_-_1776352 1.11 ENSDART00000123089
DnaJ (Hsp40) homolog, subfamily C, member 2
chr21_-_11970199 1.11 ENSDART00000114524
NOP56 ribonucleoprotein homolog
chr17_-_40110782 1.11 ENSDART00000126929
si:dkey-187k19.2
chr11_+_31236001 1.10 ENSDART00000129393
tRNA methyltransferase 1
chr14_-_6285555 1.10 ENSDART00000182280
ENSDART00000147184
elongator complex protein 1
chr15_-_23721618 1.10 ENSDART00000109318
zinc finger CCCH-type containing 4
chr2_+_3823813 1.10 ENSDART00000103596
ENSDART00000161880
ENSDART00000185408
Niemann-Pick disease, type C1
chr9_+_41024973 1.09 ENSDART00000014660
ENSDART00000144467
ORMDL sphingolipid biosynthesis regulator 1
chr13_+_28690355 1.09 ENSDART00000137475
ENSDART00000128246
polymerase (RNA) I polypeptide C
chr24_+_39105051 1.09 ENSDART00000115297
MSS51 mitochondrial translational activator
chr3_+_6443992 1.09 ENSDART00000169325
ENSDART00000162255
nucleoporin 85
chr3_+_23726148 1.09 ENSDART00000174580
homeobox B3a
chr2_+_19163965 1.08 ENSDART00000166073
ELOVL fatty acid elongase 1a
chr18_+_29898955 1.08 ENSDART00000064080
centromere protein N
chr23_+_36122058 1.08 ENSDART00000184448
homeobox C3a
chr14_+_4276394 1.07 ENSDART00000038301
glucosamine-6-phosphate deaminase 2
chr22_-_11648322 1.07 ENSDART00000109596
dipeptidyl-peptidase 4
chr9_+_32178374 1.07 ENSDART00000078576
coenzyme Q10B
chr6_-_50704689 1.07 ENSDART00000074100
oxidative stress induced growth inhibitor 1
chr22_-_11648094 1.07 ENSDART00000191791
dipeptidyl-peptidase 4
chr8_-_17926814 1.06 ENSDART00000147344
LIM homeobox 8b
chr19_-_2317558 1.06 ENSDART00000190300
sp8 transcription factor a
chr10_+_8197827 1.06 ENSDART00000026244
Mtr4 exosome RNA helicase
chr2_+_25839650 1.06 ENSDART00000134077
ENSDART00000140804
eukaryotic translation initiation factor 5A2
chr17_+_51906053 1.05 ENSDART00000159072
ENSDART00000056869
feline leukemia virus subgroup C cellular receptor family, member 2a
chr2_+_12349870 1.05 ENSDART00000134083
Rho GTPase activating protein 21b
chr12_+_19191787 1.04 ENSDART00000152892
solute carrier family 16 (monocarboxylate transporter), member 8
chr24_+_11908480 1.04 ENSDART00000024224
flap structure-specific endonuclease 1
chr14_+_34490445 1.04 ENSDART00000132193
ENSDART00000148044
wingless-type MMTV integration site family, member 8a

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa11b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.3 GO:0006524 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.9 2.7 GO:2000793 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.9 9.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.8 2.3 GO:0055026 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.8 2.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.6 1.8 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.6 2.2 GO:0072045 convergent extension involved in nephron morphogenesis(GO:0072045)
0.5 2.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.5 3.1 GO:0097065 anterior head development(GO:0097065)
0.5 1.9 GO:0019532 oxalate transport(GO:0019532)
0.5 2.3 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.4 3.1 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.4 1.8 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.4 1.3 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.4 1.7 GO:0060019 radial glial cell differentiation(GO:0060019)
0.4 1.6 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.4 1.6 GO:0048313 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.4 1.1 GO:0009229 thiamine diphosphate biosynthetic process(GO:0009229)
0.4 2.6 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.4 1.1 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.4 0.7 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.4 1.1 GO:0006043 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.3 1.4 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.3 1.4 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.3 1.0 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.3 1.0 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.3 1.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.3 1.0 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.3 1.9 GO:0030823 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.3 0.9 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.3 1.8 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.3 1.5 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.3 1.5 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.3 2.0 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.3 2.3 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.3 1.4 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.3 1.1 GO:1900060 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.3 1.6 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.3 1.9 GO:0006921 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.3 0.8 GO:0035331 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.3 1.6 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.3 1.0 GO:0097037 heme export(GO:0097037)
0.2 1.0 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.2 1.7 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2 1.2 GO:0033688 regulation of osteoblast proliferation(GO:0033688) craniofacial suture morphogenesis(GO:0097094)
0.2 0.7 GO:0010656 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.2 1.1 GO:1902804 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 0.7 GO:0042373 vitamin K metabolic process(GO:0042373)
0.2 1.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.2 0.9 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.2 1.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.2 0.9 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.2 0.6 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.2 2.9 GO:0006415 translational termination(GO:0006415)
0.2 1.2 GO:0035909 aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.2 1.6 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.2 0.8 GO:0051645 Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661)
0.2 1.0 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.2 2.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 1.0 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.2 0.8 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.2 2.9 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.2 1.7 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.2 0.8 GO:0000338 protein deneddylation(GO:0000338)
0.2 0.4 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.2 1.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.2 0.7 GO:0034969 histone arginine methylation(GO:0034969)
0.2 1.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.2 0.7 GO:0042306 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.2 1.1 GO:0030308 negative regulation of cell growth(GO:0030308)
0.2 1.4 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.2 0.5 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.2 0.7 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2 3.8 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.2 0.7 GO:0006499 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.2 1.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.2 0.8 GO:0090527 actin filament reorganization(GO:0090527)
0.2 1.0 GO:0006574 valine catabolic process(GO:0006574)
0.2 1.7 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.2 0.8 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 1.2 GO:0044211 CTP salvage(GO:0044211)
0.1 0.6 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.6 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.9 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.4 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.1 1.3 GO:0009791 post-embryonic development(GO:0009791)
0.1 0.8 GO:0061641 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 2.7 GO:0031297 replication fork processing(GO:0031297)
0.1 0.6 GO:0061549 sympathetic ganglion development(GO:0061549)
0.1 1.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.5 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.1 4.8 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1 0.9 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.5 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 2.1 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.6 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.1 0.9 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 0.6 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591)
0.1 0.9 GO:2001271 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.6 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 2.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.7 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.1 3.2 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 0.2 GO:0001839 neural plate morphogenesis(GO:0001839)
0.1 2.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.7 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 0.6 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 1.3 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.7 GO:0015809 arginine transport(GO:0015809)
0.1 2.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.6 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 1.7 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 1.1 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 0.3 GO:0030910 olfactory placode formation(GO:0030910)
0.1 1.0 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 2.0 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.7 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.1 0.7 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 4.3 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.1 2.2 GO:0021884 forebrain neuron development(GO:0021884)
0.1 0.3 GO:1900180 snRNA modification(GO:0040031) regulation of protein localization to nucleus(GO:1900180) positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 1.6 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.7 GO:0031179 peptide modification(GO:0031179)
0.1 0.6 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 0.2 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 1.0 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.1 1.1 GO:0051382 kinetochore assembly(GO:0051382)
0.1 2.1 GO:0060030 dorsal convergence(GO:0060030)
0.1 0.2 GO:0002544 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.1 1.4 GO:0035459 cargo loading into vesicle(GO:0035459)
0.1 1.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.6 GO:0006829 zinc II ion transport(GO:0006829)
0.1 0.8 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.6 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.1 GO:0022009 central nervous system vasculogenesis(GO:0022009)
0.1 0.9 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.1 1.7 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.1 0.5 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 7.5 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.1 0.6 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.1 0.1 GO:0055071 manganese ion homeostasis(GO:0055071)
0.1 0.2 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347) negative regulation of adherens junction organization(GO:1903392)
0.1 0.1 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.1 0.3 GO:0045056 transcytosis(GO:0045056)
0.1 0.9 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.4 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.1 0.7 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 2.1 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.1 1.4 GO:0048264 determination of ventral identity(GO:0048264)
0.1 0.6 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.1 0.6 GO:0010721 negative regulation of cell development(GO:0010721)
0.1 0.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 1.1 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.9 GO:0010458 exit from mitosis(GO:0010458)
0.1 0.7 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 1.3 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 1.6 GO:0051028 mRNA transport(GO:0051028)
0.1 1.7 GO:0048538 thymus development(GO:0048538)
0.1 0.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 2.2 GO:0051781 positive regulation of cell division(GO:0051781)
0.1 1.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 2.9 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 0.4 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 2.7 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 4.3 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 3.2 GO:0034504 protein localization to nucleus(GO:0034504)
0.0 0.3 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.5 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.8 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.5 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 1.1 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 1.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.5 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.2 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.0 0.4 GO:1901989 positive regulation of cell cycle phase transition(GO:1901989)
0.0 0.5 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.7 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 1.2 GO:0032231 regulation of actin filament bundle assembly(GO:0032231)
0.0 0.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.6 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 1.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.3 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 1.3 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.7 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.0 1.0 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.8 GO:0006298 mismatch repair(GO:0006298)
0.0 8.1 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 1.6 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.6 GO:0006623 protein targeting to vacuole(GO:0006623) establishment of protein localization to vacuole(GO:0072666)
0.0 0.7 GO:0051788 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 1.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.7 GO:0035924 cellular response to vascular endothelial growth factor stimulus(GO:0035924)
0.0 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.7 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.9 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.4 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.0 0.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 5.6 GO:0016197 endosomal transport(GO:0016197)
0.0 1.5 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.6 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 1.0 GO:0032543 mitochondrial translation(GO:0032543)
0.0 2.0 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 1.8 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.8 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 1.7 GO:0051225 spindle assembly(GO:0051225)
0.0 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.0 0.2 GO:0035627 ceramide transport(GO:0035627)
0.0 0.4 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.2 GO:0016072 rRNA metabolic process(GO:0016072)
0.0 0.5 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.8 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 0.2 GO:0031113 regulation of microtubule polymerization(GO:0031113)
0.0 0.8 GO:0030199 collagen fibril organization(GO:0030199)
0.0 2.9 GO:0008033 tRNA processing(GO:0008033)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.7 GO:0097061 dendritic spine morphogenesis(GO:0060997) dendritic spine organization(GO:0097061)
0.0 0.0 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.7 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.7 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.9 GO:0039021 pronephric glomerulus development(GO:0039021)
0.0 0.7 GO:0031647 regulation of protein stability(GO:0031647)
0.0 0.7 GO:0035337 fatty-acyl-CoA metabolic process(GO:0035337)
0.0 0.1 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 1.1 GO:0006414 translational elongation(GO:0006414)
0.0 0.2 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.7 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 1.7 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.9 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.3 GO:0032438 melanosome organization(GO:0032438) pigment granule organization(GO:0048753)
0.0 0.4 GO:0032355 response to estradiol(GO:0032355)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 1.5 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.2 GO:0061337 cardiac conduction(GO:0061337)
0.0 0.1 GO:0007624 ultradian rhythm(GO:0007624)
0.0 0.4 GO:0006399 tRNA metabolic process(GO:0006399)
0.0 0.0 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 1.1 GO:0048545 response to steroid hormone(GO:0048545)
0.0 0.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 1.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0015867 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) purine-containing compound transmembrane transport(GO:0072530) mitochondrial ATP transmembrane transport(GO:1990544)
0.0 0.2 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 0.2 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.4 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 0.4 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.7 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.6 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 1.1 GO:0008213 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0 0.6 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)
0.0 0.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.6 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 1.1 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.5 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 1.1 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.1 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.4 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 1.3 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 1.0 GO:0032259 methylation(GO:0032259)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.5 1.5 GO:0030689 Noc complex(GO:0030689)
0.5 1.4 GO:0034457 Mpp10 complex(GO:0034457)
0.4 1.8 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.4 1.7 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.4 2.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.3 1.0 GO:0097189 apoptotic body(GO:0097189)
0.3 1.0 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.3 2.0 GO:0005784 Sec61 translocon complex(GO:0005784)
0.3 1.0 GO:0030896 checkpoint clamp complex(GO:0030896)
0.3 2.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.3 1.5 GO:0070390 transcription export complex 2(GO:0070390)
0.3 2.0 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.3 1.1 GO:0035339 SPOTS complex(GO:0035339)
0.3 2.9 GO:0035101 FACT complex(GO:0035101)
0.3 2.3 GO:0071797 LUBAC complex(GO:0071797)
0.2 0.7 GO:0034515 proteasome storage granule(GO:0034515)
0.2 0.9 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.2 0.9 GO:0005880 nuclear microtubule(GO:0005880)
0.2 0.6 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.2 1.3 GO:0016589 NURF complex(GO:0016589)
0.2 1.3 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.2 0.7 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 1.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 0.7 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.2 1.8 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.2 0.9 GO:0043198 dendritic shaft(GO:0043198)
0.2 1.2 GO:0030681 fibrillar center(GO:0001650) multimeric ribonuclease P complex(GO:0030681)
0.2 1.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.2 0.6 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.2 0.6 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 1.6 GO:0030904 retromer complex(GO:0030904)
0.1 1.0 GO:0000798 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 1.1 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 2.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.8 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 3.2 GO:0035371 microtubule plus-end(GO:0035371)
0.1 2.9 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.7 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 1.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 1.3 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.4 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.1 1.1 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.4 GO:0031209 SCAR complex(GO:0031209)
0.1 0.4 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 2.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 1.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.3 GO:0031213 RSF complex(GO:0031213)
0.1 1.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 3.4 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.8 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.8 GO:0032300 mismatch repair complex(GO:0032300)
0.1 0.6 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 4.0 GO:0005643 nuclear pore(GO:0005643)
0.1 0.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 4.5 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.1 1.5 GO:0032040 small-subunit processome(GO:0032040)
0.1 1.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 1.5 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.1 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 4.7 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1 3.3 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 1.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.3 GO:0071439 clathrin complex(GO:0071439)
0.1 0.4 GO:0030428 cell septum(GO:0030428)
0.1 0.7 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.6 GO:0098833 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 1.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.7 GO:0042555 MCM complex(GO:0042555)
0.0 0.8 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.5 GO:0000177 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 2.4 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 1.0 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.9 GO:0032039 integrator complex(GO:0032039)
0.0 3.7 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 2.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 3.2 GO:0005795 Golgi stack(GO:0005795)
0.0 1.5 GO:0008305 integrin complex(GO:0008305)
0.0 3.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.2 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 1.5 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.5 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.5 GO:0043209 myelin sheath(GO:0043209)
0.0 3.8 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.3 GO:0044545 NSL complex(GO:0044545)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 2.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.2 GO:0070822 Sin3-type complex(GO:0070822)
0.0 4.9 GO:0005730 nucleolus(GO:0005730)
0.0 1.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.5 GO:0000502 proteasome complex(GO:0000502)
0.0 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.4 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 8.1 GO:0005694 chromosome(GO:0005694)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.3 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 75.3 GO:0005634 nucleus(GO:0005634)
0.0 0.8 GO:0031902 late endosome membrane(GO:0031902)
0.0 2.2 GO:0005813 centrosome(GO:0005813)
0.0 0.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 11.0 GO:0005829 cytosol(GO:0005829)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 9.4 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.3 5.3 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.6 1.7 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.4 1.8 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.4 3.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.4 2.9 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.4 1.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.4 1.8 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.4 1.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.4 1.4 GO:0044548 S100 protein binding(GO:0044548)
0.3 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.3 1.0 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.3 1.3 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.3 1.9 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.3 1.2 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.3 0.9 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.3 0.9 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.3 1.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.3 1.9 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.3 3.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.3 1.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.3 1.6 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.3 1.8 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 2.3 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.3 1.0 GO:0051059 NF-kappaB binding(GO:0051059)
0.2 0.7 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.2 1.0 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.2 0.7 GO:0045545 syndecan binding(GO:0045545)
0.2 0.7 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 1.3 GO:0008142 oxysterol binding(GO:0008142)
0.2 0.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 0.6 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.2 0.6 GO:0030623 U5 snRNA binding(GO:0030623)
0.2 1.7 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.2 1.6 GO:0009378 four-way junction helicase activity(GO:0009378)
0.2 3.1 GO:0030515 snoRNA binding(GO:0030515)
0.2 1.6 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2 0.7 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2 0.5 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.2 0.7 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.2 0.8 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 2.0 GO:0005537 mannose binding(GO:0005537)
0.2 2.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 1.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 1.2 GO:0004849 uridine kinase activity(GO:0004849)
0.2 1.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.2 2.3 GO:2001069 glycogen binding(GO:2001069)
0.1 0.7 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.1 0.7 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 1.0 GO:0034632 retinol transporter activity(GO:0034632)
0.1 0.5 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 0.9 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.5 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.1 1.0 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.9 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 1.0 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 1.0 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.8 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.6 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.1 1.1 GO:0048039 ubiquinone binding(GO:0048039)
0.1 2.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.6 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.1 6.1 GO:0043022 ribosome binding(GO:0043022)
0.1 0.9 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 1.6 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.8 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 1.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.9 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.3 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.1 3.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.0 GO:0008263 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.1 1.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.6 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.1 1.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.2 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 2.1 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 1.2 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 2.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.3 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 1.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 2.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.5 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.1 1.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 2.5 GO:0030165 PDZ domain binding(GO:0030165)
0.1 0.4 GO:0043531 ADP binding(GO:0043531)
0.1 0.7 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 6.5 GO:0003724 RNA helicase activity(GO:0003724)
0.1 1.9 GO:0004312 fatty acid synthase activity(GO:0004312)
0.1 0.3 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 0.5 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.2 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.1 1.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.7 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 1.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 2.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.7 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 1.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 2.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 1.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.5 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.4 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.8 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 0.4 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 0.8 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.5 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.4 GO:0004100 chitin synthase activity(GO:0004100)
0.1 1.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 2.0 GO:0000049 tRNA binding(GO:0000049)
0.1 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.6 GO:0052813 phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.7 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 1.9 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.3 GO:0045735 nutrient reservoir activity(GO:0045735)
0.0 1.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.6 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 1.1 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.4 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.2 GO:0035620 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.7 GO:0015026 coreceptor activity(GO:0015026)
0.0 2.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 3.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.4 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 1.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 1.5 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.4 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 4.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.2 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.8 GO:0005518 collagen binding(GO:0005518)
0.0 1.4 GO:0008013 beta-catenin binding(GO:0008013)
0.0 3.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.8 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 4.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0016805 dipeptidase activity(GO:0016805)
0.0 3.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 2.3 GO:0045296 cadherin binding(GO:0045296)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 6.8 GO:0003682 chromatin binding(GO:0003682)
0.0 0.3 GO:0008187 poly-pyrimidine tract binding(GO:0008187) poly(U) RNA binding(GO:0008266)
0.0 1.9 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.0 1.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.5 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 42.7 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 1.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.0 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.3 GO:0015923 mannosidase activity(GO:0015923)
0.0 0.4 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.3 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 1.3 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.7 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 1.1 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.7 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 2.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.9 GO:0008083 growth factor activity(GO:0008083)
0.0 0.2 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 11.9 GO:0003723 RNA binding(GO:0003723)
0.0 1.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 10.1 PID E2F PATHWAY E2F transcription factor network
0.1 3.8 PID MYC PATHWAY C-MYC pathway
0.1 3.1 PID ATM PATHWAY ATM pathway
0.1 2.7 PID BARD1 PATHWAY BARD1 signaling events
0.1 3.5 PID AURORA B PATHWAY Aurora B signaling
0.1 1.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 0.9 PID IL5 PATHWAY IL5-mediated signaling events
0.1 2.4 PID FOXO PATHWAY FoxO family signaling
0.1 2.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 1.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 1.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 1.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.3 PID ATR PATHWAY ATR signaling pathway
0.1 0.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 2.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 1.5 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.9 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 2.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.8 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.6 PID TNF PATHWAY TNF receptor signaling pathway
0.0 2.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID BCR 5PATHWAY BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.4 3.2 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.2 2.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 2.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.2 2.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 2.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 5.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 2.6 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1 2.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 1.5 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 3.1 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 1.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.9 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.1 3.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 1.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 3.0 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.1 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.0 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 1.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 0.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 0.5 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 0.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 2.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.7 REACTOME RNA POL II PRE TRANSCRIPTION EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.0 0.4 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 2.0 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.2 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.9 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 1.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.1 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.7 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis