Project

PRJEB1986: zebrafish developmental stages transcriptome

Navigation
Downloads

Results for hoxb1a+hoxb1b-2

Z-value: 0.86

Motif logo

logo of

Transcription factors associated with hoxb1a+hoxb1b-2

Gene Symbol Gene ID Gene Info
hoxb1a
ENSDARG00000008174 homeobox B1a
hoxb1b-2
ENSDARG00000112663 homeobox B1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxb1adr11_v1_chr3_+_23768898_23768898-0.917.5e-08Click!

Activity profile of hoxb1a+hoxb1b-2 motif

Sorted Z-values of hoxb1a+hoxb1b-2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_22003942 5.31 ENSDART00000091013
si:dkey-57a22.15
si:dkey-57a22.15
chr8_+_6954984 4.34 ENSDART00000145610
si:ch211-255g12.6
si:ch211-255g12.6
chr24_-_40009446 3.68 ENSDART00000087422
aoc1
amine oxidase, copper containing 1
chr13_-_51065048 3.33 ENSDART00000168085
CABZ01078663.1

chr22_-_600016 2.47 ENSDART00000086434
tmcc2
transmembrane and coiled-coil domain family 2
chr7_-_13381129 2.41 ENSDART00000164326
si:ch73-119p20.1
si:ch73-119p20.1
chr12_-_25916530 2.36 ENSDART00000186386
sncgb
synuclein, gamma b (breast cancer-specific protein 1)
chr14_-_7888748 2.26 ENSDART00000166293
ppp3cb
protein phosphatase 3, catalytic subunit, beta isozyme
chr25_+_20215964 2.18 ENSDART00000139235
tnnt2d
troponin T2d, cardiac
chr8_-_39903803 2.07 ENSDART00000012391
cabp1a
calcium binding protein 1a
chr3_+_29714775 2.03 ENSDART00000041388
cacng2a
calcium channel, voltage-dependent, gamma subunit 2a
chr23_+_20408227 2.01 ENSDART00000134727
si:rp71-17i16.4
si:rp71-17i16.4
chr11_+_30817943 1.99 ENSDART00000150130
ENSDART00000159997
cacna1ab
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b
chr1_-_20911297 1.96 ENSDART00000078271
cpe
carboxypeptidase E
chr1_-_14258409 1.95 ENSDART00000079359
pde5aa
phosphodiesterase 5A, cGMP-specific, a
chr22_-_13544244 1.93 ENSDART00000110136
cntnap5b
contactin associated protein-like 5b
chr10_+_439692 1.92 ENSDART00000147740
zdhhc8a
zinc finger, DHHC-type containing 8a
chr14_-_36378494 1.91 ENSDART00000058503
gpm6aa
glycoprotein M6Aa
chr10_-_27049170 1.89 ENSDART00000143451
cnih2
cornichon family AMPA receptor auxiliary protein 2
chr4_+_21129752 1.83 ENSDART00000169764
syt1a
synaptotagmin Ia
chr10_+_466926 1.81 ENSDART00000145220
arvcfa
ARVCF, delta catenin family member a
chr4_+_26496489 1.76 ENSDART00000160652
iqsec3a
IQ motif and Sec7 domain 3a
chr8_+_44703864 1.76 ENSDART00000016225
star
steroidogenic acute regulatory protein
chr22_+_3223489 1.75 ENSDART00000082011
lim2.2
lens intrinsic membrane protein 2.2
chr25_+_20216159 1.72 ENSDART00000048642
tnnt2d
troponin T2d, cardiac
chr22_-_16997475 1.64 ENSDART00000090237
nfia
nuclear factor I/A
chr3_-_57744323 1.63 ENSDART00000101829
lgals3bpb
lectin, galactoside-binding, soluble, 3 binding protein b
chr16_+_46111849 1.62 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr2_+_2223837 1.57 ENSDART00000101038
ENSDART00000129354
tmie
transmembrane inner ear
chr16_-_13388821 1.53 ENSDART00000144062
grin2db
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr16_-_17175731 1.44 ENSDART00000183057
opn9
opsin 9
chr8_-_44015210 1.31 ENSDART00000186879
ENSDART00000188965
ENSDART00000001313
ENSDART00000188902
ENSDART00000185935
ENSDART00000147869
rimbp2
rimbp2
RIMS binding protein 2
RIMS binding protein 2
chr8_-_5220125 1.30 ENSDART00000035676
bnip3la
BCL2 interacting protein 3 like a
chr10_+_7563755 1.26 ENSDART00000165877
purg
purine-rich element binding protein G
chr18_+_28102620 1.25 ENSDART00000132342
kiaa1549lb
KIAA1549-like b
chr3_-_18675688 1.24 ENSDART00000048218
slc5a11
solute carrier family 5 (sodium/inositol cotransporter), member 11
chr13_-_31829786 1.23 ENSDART00000138667
sertad4
SERTA domain containing 4
chr16_-_31188715 1.21 ENSDART00000058829
scrt1b
scratch family zinc finger 1b
chr17_-_20897407 1.21 ENSDART00000149481
ank3b
ankyrin 3b
chr14_+_34547554 1.20 ENSDART00000074819
gabrp
gamma-aminobutyric acid (GABA) A receptor, pi
chr20_-_49650293 1.18 ENSDART00000151239
col12a1b
collagen, type XII, alpha 1b
chr7_-_52842007 1.17 ENSDART00000182710
map1aa
microtubule-associated protein 1Aa
chr12_-_10220036 1.14 ENSDART00000134619
mpp2b
membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2)
chr24_+_32472155 1.14 ENSDART00000098859
neurod6a
neuronal differentiation 6a
chr1_-_8428736 1.12 ENSDART00000138435
ENSDART00000121823
syngr3b
synaptogyrin 3b
chr1_-_38709551 1.09 ENSDART00000128794
gpm6ab
glycoprotein M6Ab
chr3_-_35800221 1.06 ENSDART00000031390
caskin1
CASK interacting protein 1
chr5_-_22544151 1.03 ENSDART00000006474
glra4b
glycine receptor, alpha 4b
chr17_+_40684 1.02 ENSDART00000164231
CABZ01111555.1

chr20_-_30369598 1.01 ENSDART00000144549
allc
allantoicase
chr7_+_25036188 0.99 ENSDART00000163957
ENSDART00000169749
sb:cb1058
sb:cb1058
chr2_+_33541928 0.98 ENSDART00000162852
BX548164.1

chr7_+_13464878 0.94 ENSDART00000172969
dagla
diacylglycerol lipase, alpha
chr7_+_7151832 0.91 ENSDART00000109485
gal3st3
galactose-3-O-sulfotransferase 3
chr17_-_20897250 0.89 ENSDART00000088106
ank3b
ankyrin 3b
chr25_-_13842618 0.86 ENSDART00000160258
mapk8ip1a
mitogen-activated protein kinase 8 interacting protein 1a
chr9_+_20781047 0.85 ENSDART00000139174
fam46c
family with sequence similarity 46, member C
chr6_+_3640381 0.85 ENSDART00000172078
col28a2b
collagen, type XXVIII, alpha 2b
chr7_+_29952719 0.83 ENSDART00000173737
tpma
alpha-tropomyosin
chr11_-_25213651 0.80 ENSDART00000097316
ENSDART00000152186
myh7ba
myosin, heavy chain 7B, cardiac muscle, beta a
chr4_+_4272622 0.80 ENSDART00000164810
ano2
anoctamin 2
chr3_+_37824268 0.79 ENSDART00000137038
asic2
acid-sensing (proton-gated) ion channel 2
chr7_+_31879649 0.77 ENSDART00000099789
mybpc3
myosin binding protein C, cardiac
chr20_+_1088658 0.77 ENSDART00000162991
BX537249.1

chr9_+_20780813 0.77 ENSDART00000142787
fam46c
family with sequence similarity 46, member C
chr15_-_33304133 0.74 ENSDART00000186092
nbeab
neurobeachin b
chr10_+_7564106 0.74 ENSDART00000159042
purg
purine-rich element binding protein G
chr17_-_7436766 0.74 ENSDART00000162002
grm1b
glutamate receptor, metabotropic 1b
chr17_+_19626479 0.73 ENSDART00000044993
ENSDART00000131863
rgs7a
regulator of G protein signaling 7a
chr25_+_7461624 0.73 ENSDART00000170569
syt12
synaptotagmin XII
chr22_-_16997246 0.70 ENSDART00000090242
nfia
nuclear factor I/A
chr1_-_9227804 0.69 ENSDART00000190360
gng13a
guanine nucleotide binding protein (G protein), gamma 13a
chr24_-_20016817 0.68 ENSDART00000082201
ENSDART00000189448
slc22a13b
solute carrier family 22 member 13b
chr17_-_20394566 0.68 ENSDART00000154667
sorcs3b
sortilin related VPS10 domain containing receptor 3b
chr11_+_37201483 0.67 ENSDART00000160930
ENSDART00000173439
ENSDART00000171273
zgc:112265
zgc:112265
chr10_+_32646402 0.64 ENSDART00000137244
zbtb21
zinc finger and BTB domain containing 21
chr25_-_35497055 0.60 ENSDART00000009271
slc5a12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr2_-_45630823 0.58 ENSDART00000183553
CR450720.1

chr2_+_55984788 0.49 ENSDART00000183599
nmrk2
nicotinamide riboside kinase 2
chr8_-_39739056 0.48 ENSDART00000147992
si:ch211-170d8.5
si:ch211-170d8.5
chr17_+_51764310 0.48 ENSDART00000157171
si:ch211-168d23.3
si:ch211-168d23.3
chr23_-_11870962 0.47 ENSDART00000143481
si:dkey-178k16.1
si:dkey-178k16.1
chr1_-_49505449 0.45 ENSDART00000187294
ENSDART00000132171
si:dkeyp-80c12.5
si:dkeyp-80c12.5
chr1_+_34181581 0.45 ENSDART00000146042
epha6
eph receptor A6
chr24_-_39518599 0.45 ENSDART00000145606
ENSDART00000031486
lyrm1
LYR motif containing 1
chr10_-_2527342 0.43 ENSDART00000184168
CU856539.1

chr6_+_4255319 0.43 ENSDART00000170351
nbeal1
neurobeachin-like 1
chr2_+_29249204 0.43 ENSDART00000168957
cdh18a
cadherin 18, type 2a
chr1_-_20826023 0.41 ENSDART00000054472
tll1
tolloid-like 1
chr2_+_17451656 0.41 ENSDART00000163620
BX640408.1

chr2_-_16216568 0.40 ENSDART00000173758
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr6_-_53143667 0.38 ENSDART00000079694
gnai2b
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
chr6_-_4214297 0.36 ENSDART00000191433
trak2
trafficking protein, kinesin binding 2
chr8_+_6410933 0.35 ENSDART00000168789
lrrtm4l2
leucine rich repeat transmembrane neuronal 4 like 2
chr4_-_13255700 0.35 ENSDART00000162277
ENSDART00000026593
grip1
glutamate receptor interacting protein 1
chr19_+_4463389 0.35 ENSDART00000168805
kcnk9
potassium channel, subfamily K, member 9
chr19_+_13994563 0.33 ENSDART00000164696
tmem222b
transmembrane protein 222b
chr5_-_7199998 0.32 ENSDART00000167316
CABZ01087502.1

chr21_-_25395223 0.28 ENSDART00000016219
ppme1
protein phosphatase methylesterase 1
chr5_-_52921532 0.24 ENSDART00000160566
CU695117.1

chr2_-_16217344 0.22 ENSDART00000152031
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr17_-_50233493 0.21 ENSDART00000172266
fosaa
v-fos FBJ murine osteosarcoma viral oncogene homolog Aa
chr10_+_37182626 0.21 ENSDART00000137636
ksr1a
kinase suppressor of ras 1a
chr16_+_25196572 0.21 ENSDART00000141956
tyrobp
TYRO protein tyrosine kinase binding protein
chr23_+_27782071 0.20 ENSDART00000131379
kmt2d
lysine (K)-specific methyltransferase 2D
chr20_-_25369767 0.19 ENSDART00000180278
itsn2a
intersectin 2a
chr10_+_1396940 0.18 ENSDART00000150096
gdnfa
glial cell derived neurotrophic factor a
chr11_+_2600612 0.18 ENSDART00000173442
dnajc14
DnaJ (Hsp40) homolog, subfamily C, member 14
chr22_+_35089031 0.17 ENSDART00000076040
srfa
serum response factor a
chr2_-_26563978 0.16 ENSDART00000150016
glis1a
GLIS family zinc finger 1a
chr4_-_17642168 0.13 ENSDART00000007030
klhl42
kelch-like family, member 42
chr16_-_37964325 0.11 ENSDART00000148801
mrap2a
melanocortin 2 receptor accessory protein 2a
chr3_-_51109286 0.08 ENSDART00000172010
si:ch211-148f13.1
si:ch211-148f13.1
chr7_+_4386753 0.07 ENSDART00000172915
slc12a10.3
slc12a10.3 solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 3
chr5_+_6617401 0.07 ENSDART00000060532
zgc:110796
zgc:110796
chr9_+_22351443 0.06 ENSDART00000080054
crygs3
crystallin, gamma S3
chr2_+_25657958 0.05 ENSDART00000161407
tnika
TRAF2 and NCK interacting kinase a
chr3_-_21062706 0.04 ENSDART00000155605
ENSDART00000153686
ENSDART00000157168
ENSDART00000156614
ENSDART00000155743
ENSDART00000156275
fam57ba
family with sequence similarity 57, member Ba
chr1_-_10577945 0.03 ENSDART00000179237
ENSDART00000040502
ENSDART00000186876
trpc5a
transient receptor potential cation channel, subfamily C, member 5a
chr24_+_39518774 0.03 ENSDART00000132939
dcun1d3
defective in cullin neddylation 1 domain containing 3
chr20_-_35841570 0.02 ENSDART00000037855
tnfrsf21
tumor necrosis factor receptor superfamily, member 21
chr17_+_28102487 0.02 ENSDART00000131638
ENSDART00000076265
zgc:91908
zgc:91908
chr16_-_32582798 0.02 ENSDART00000137936
fbxl4
F-box and leucine-rich repeat protein 4
chr3_-_1283247 0.01 ENSDART00000149814
tcf20
transcription factor 20
chr25_+_2668892 0.01 ENSDART00000122929
bbs4
Bardet-Biedl syndrome 4
chr16_-_1502699 0.01 ENSDART00000187189
sim1a
single-minded family bHLH transcription factor 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxb1a+hoxb1b-2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.7 GO:0046677 response to antibiotic(GO:0046677)
0.3 1.0 GO:0000256 allantoin catabolic process(GO:0000256)
0.3 1.8 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.2 0.9 GO:0071926 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.2 1.9 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.2 0.8 GO:0003210 cardiac atrium formation(GO:0003210)
0.2 2.3 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.2 3.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 2.5 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 1.3 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 1.5 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 2.0 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.1 5.9 GO:0006937 regulation of muscle contraction(GO:0006937)
0.1 0.4 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.1 1.9 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.7 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.1 2.4 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.1 1.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.6 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.2 GO:0071635 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635)
0.1 1.0 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.2 GO:0061217 regulation of neurotransmitter uptake(GO:0051580) regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.4 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.1 0.7 GO:0050909 sensory perception of taste(GO:0050909)
0.0 1.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 1.2 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 1.8 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 5.4 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.4 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.3 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 1.4 GO:0007602 phototransduction(GO:0007602)
0.0 0.5 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.7 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.2 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 1.4 GO:0021549 cerebellum development(GO:0021549)
0.0 1.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.9 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.9 GO:0046328 regulation of JNK cascade(GO:0046328)
0.0 2.0 GO:0016485 protein processing(GO:0016485)
0.0 0.1 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 1.6 GO:0006836 neurotransmitter transport(GO:0006836)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.3 GO:0005955 calcineurin complex(GO:0005955)
0.4 1.8 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 3.0 GO:0044295 axonal growth cone(GO:0044295)
0.1 5.9 GO:0005861 troponin complex(GO:0005861)
0.1 1.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.4 GO:0043679 axon terminus(GO:0043679)
0.1 1.1 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.8 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 1.2 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.6 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.5 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.2 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:1903136 cuprous ion binding(GO:1903136)
0.7 3.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.4 2.3 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.4 3.9 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.3 2.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 1.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.9 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.6 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1 1.9 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 1.0 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 1.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.7 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 0.9 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 7.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.9 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 1.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 2.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.5 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 2.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.8 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 2.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.0 2.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0031781 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 1.3 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 2.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.8 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.2 REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.0 0.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK