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PRJEB1986: zebrafish developmental stages transcriptome

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Results for hoxb2a

Z-value: 0.72

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Transcription factors associated with hoxb2a

Gene Symbol Gene ID Gene Info
hoxb2a
ENSDARG00000000175 homeobox B2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxb2adr11_v1_chr3_+_23752150_237521500.561.3e-02Click!

Activity profile of hoxb2a motif

Sorted Z-values of hoxb2a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_14507567 4.17 ENSDART00000015681
dbx1b
developing brain homeobox 1b
chr21_-_37973819 2.12 ENSDART00000133405
ripply1
ripply transcriptional repressor 1
chr3_-_16719244 1.95 ENSDART00000055859
pold1
polymerase (DNA directed), delta 1, catalytic subunit
chr11_-_35171768 1.79 ENSDART00000192896
traip
TRAF-interacting protein
chr1_-_999556 1.74 ENSDART00000170884
ENSDART00000172235
gart
phosphoribosylglycinamide formyltransferase
chr8_+_23355484 1.70 ENSDART00000085361
ENSDART00000125729
dnmt3ba
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a
chr16_+_29509133 1.68 ENSDART00000112116
ctss2.1
cathepsin S, ortholog2, tandem duplicate 1
chr13_-_21660203 1.60 ENSDART00000100925
mxtx1
mix-type homeobox gene 1
chr18_+_619619 1.57 ENSDART00000159846
prtga
protogenin homolog a (Gallus gallus)
chr10_-_35257458 1.44 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
prr11
proline rich 11
chr17_-_16422654 1.41 ENSDART00000150149
tdp1
tyrosyl-DNA phosphodiesterase 1
chr20_-_27225876 1.40 ENSDART00000149204
ENSDART00000149732
si:dkey-85n7.7
si:dkey-85n7.7
chr1_-_55248496 1.40 ENSDART00000098615
nanos3
nanos homolog 3
chr11_-_25418856 1.38 ENSDART00000013714
gata1a
GATA binding protein 1a
chr4_+_9177997 1.36 ENSDART00000057254
ENSDART00000154614
nfyba
nuclear transcription factor Y, beta a
chr8_-_50888806 1.36 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr3_+_26244353 1.33 ENSDART00000103733
atad5a
ATPase family, AAA domain containing 5a
chr10_-_44560165 1.32 ENSDART00000181217
ENSDART00000076084
npm2b
nucleophosmin/nucleoplasmin, 2b
chr17_+_8799451 1.30 ENSDART00000189814
ENSDART00000191577
tonsl
tonsoku-like, DNA repair protein
chr8_+_30452945 1.30 ENSDART00000062303
foxd5
forkhead box D5
chr12_-_33817114 1.30 ENSDART00000161265
twnk
twinkle mtDNA helicase
chr23_-_23401305 1.23 ENSDART00000078936
her9
hairy-related 9
chr6_+_41191482 1.23 ENSDART00000000877
opn1mw3
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr17_+_16046132 1.20 ENSDART00000155005
si:ch73-204p21.2
si:ch73-204p21.2
chr17_+_21295132 1.16 ENSDART00000103845
eno4
enolase family member 4
chr17_+_16046314 1.16 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr15_+_36309070 1.15 ENSDART00000157034
gmnc
geminin coiled-coil domain containing
chr25_-_21031007 1.14 ENSDART00000138985
gnaia
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr2_+_33326522 1.14 ENSDART00000056655
klf17
Kruppel-like factor 17
chr16_+_28994709 1.12 ENSDART00000088023
gon4l
gon-4-like (C. elegans)
chr21_+_43404945 1.10 ENSDART00000142234
frmd7
FERM domain containing 7
chr16_+_5908483 1.10 ENSDART00000167393
ulk4
unc-51 like kinase 4
chr21_-_19918286 1.08 ENSDART00000180816
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr11_+_33818179 1.07 ENSDART00000109418
spoplb
speckle-type POZ protein-like b
chr17_-_31611692 1.07 ENSDART00000141480
si:dkey-170l10.1
si:dkey-170l10.1
chr19_+_12406583 1.06 ENSDART00000013865
ENSDART00000151535
seh1l
SEH1-like (S. cerevisiae)
chr14_-_33945692 1.06 ENSDART00000168546
ENSDART00000189778
zdhhc24
zinc finger, DHHC-type containing 24
chr3_+_22442445 1.04 ENSDART00000190921
wnk4b
WNK lysine deficient protein kinase 4b
chr21_-_31013817 1.04 ENSDART00000065504
ncbp3
nuclear cap binding subunit 3
chr16_+_54209504 1.04 ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr7_-_25895189 1.03 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
cd99l2
CD99 molecule-like 2
chr18_+_19456648 1.02 ENSDART00000079695
zwilch
zwilch kinetochore protein
chr5_+_66433287 1.01 ENSDART00000170757
kntc1
kinetochore associated 1
chr19_+_31585917 1.01 ENSDART00000132182
gmnn
geminin, DNA replication inhibitor
chr21_+_34088110 1.01 ENSDART00000145123
ENSDART00000029599
ENSDART00000147519
mtmr1b
myotubularin related protein 1b
chr2_-_10600950 1.01 ENSDART00000160216
BX323564.1

chr6_-_40922971 0.98 ENSDART00000155363
sfi1
SFI1 centrin binding protein
chr17_+_24687338 0.98 ENSDART00000135794
selenon
selenoprotein N
chr10_+_2799285 0.97 ENSDART00000030709
pnx
posterior neuron-specific homeobox
chr3_-_26244256 0.97 ENSDART00000103741
ppp4ca
protein phosphatase 4, catalytic subunit a
chr10_+_22775253 0.96 ENSDART00000190141
tmem88a
transmembrane protein 88 a
chr10_+_16036246 0.96 ENSDART00000141586
ENSDART00000135868
ENSDART00000065037
ENSDART00000124502
lmnb1
lamin B1
chr13_+_22295905 0.96 ENSDART00000180133
ENSDART00000181125
usp54a
ubiquitin specific peptidase 54a
chr13_+_35637048 0.96 ENSDART00000085037
thbs2a
thrombospondin 2a
chr13_+_27232848 0.95 ENSDART00000138043
rin2
Ras and Rab interactor 2
chr7_+_69019851 0.94 ENSDART00000162891
CABZ01057488.1

chr1_+_513986 0.94 ENSDART00000109083
ENSDART00000081945
txnl4b
thioredoxin-like 4B
chr15_+_1534644 0.93 ENSDART00000130413
smc4
structural maintenance of chromosomes 4
chr3_+_18807006 0.92 ENSDART00000180091
tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr15_-_44052927 0.92 ENSDART00000166209
wu:fb44b02
wu:fb44b02
chr6_-_43283122 0.92 ENSDART00000186022
frmd4ba
FERM domain containing 4Ba
chr10_+_17714866 0.92 ENSDART00000039969
slc20a1b
solute carrier family 20 (phosphate transporter), member 1b
chr1_+_21731382 0.91 ENSDART00000054395
pax5
paired box 5
chr2_-_23768818 0.90 ENSDART00000148685
ENSDART00000191167
xirp1
xin actin binding repeat containing 1
chr15_-_16177603 0.89 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr12_-_35830625 0.88 ENSDART00000180028
CU459056.1

chr2_+_41526904 0.88 ENSDART00000127520
acvr1l
activin A receptor, type 1 like
chr20_-_23426339 0.87 ENSDART00000004625
zar1
zygote arrest 1
chr17_-_31695217 0.87 ENSDART00000104332
ENSDART00000143090
lin52
lin-52 DREAM MuvB core complex component
chr9_-_32753535 0.86 ENSDART00000060006
olig2
oligodendrocyte lineage transcription factor 2
chr22_-_15593824 0.85 ENSDART00000123125
tpm4a
tropomyosin 4a
chr2_-_50272077 0.84 ENSDART00000127623
cul1a
cullin 1a
chr5_+_27897504 0.84 ENSDART00000130936
adam28
ADAM metallopeptidase domain 28
chr8_+_17168114 0.83 ENSDART00000183901
cenph
centromere protein H
chr23_+_31912882 0.83 ENSDART00000140505
armc1l
armadillo repeat containing 1, like
chr14_-_25935167 0.81 ENSDART00000139855
g3bp1
GTPase activating protein (SH3 domain) binding protein 1
chr25_-_37262220 0.79 ENSDART00000153789
ENSDART00000155182
rfwd3
ring finger and WD repeat domain 3
chr24_+_19415124 0.78 ENSDART00000186931
sulf1
sulfatase 1
chr25_-_31423493 0.78 ENSDART00000027661
myod1
myogenic differentiation 1
chr2_+_20793982 0.78 ENSDART00000014785
prg4a
proteoglycan 4a
chr23_-_1017605 0.76 ENSDART00000138290
cdh26.1
cadherin 26, tandem duplicate 1
chr6_+_21001264 0.75 ENSDART00000044519
ENSDART00000151278
cx44.2
connexin 44.2
chr23_+_31913292 0.74 ENSDART00000136910
armc1l
armadillo repeat containing 1, like
chr12_+_16087077 0.74 ENSDART00000141898
znf281b
zinc finger protein 281b
chr23_+_32028574 0.74 ENSDART00000145501
ENSDART00000143121
ENSDART00000111877
tpx2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr7_-_17816175 0.73 ENSDART00000091272
ENSDART00000173757
ecsit
ECSIT signalling integrator
chr15_+_897280 0.73 ENSDART00000155470
znf1012
zinc finger protein 1012
chr13_-_42400647 0.73 ENSDART00000043069
march5
membrane-associated ring finger (C3HC4) 5
chr15_+_17345609 0.71 ENSDART00000111753
vmp1
vacuole membrane protein 1
chr23_-_31913069 0.71 ENSDART00000135526
mtfr2
mitochondrial fission regulator 2
chr23_-_20126257 0.71 ENSDART00000005021
tktb
transketolase b
chr7_+_17543487 0.71 ENSDART00000126652
CU672228.2
Danio rerio novel immune-type receptor 1l (nitr1l), mRNA.
chr7_+_34290051 0.70 ENSDART00000123498
fibinb
fin bud initiation factor b
chr10_-_41980797 0.69 ENSDART00000076575
rhof
ras homolog family member F
chr17_-_48944465 0.69 ENSDART00000154110
si:ch1073-80i24.3
si:ch1073-80i24.3
chr7_+_17106160 0.69 ENSDART00000190048
ENSDART00000180004
ENSDART00000013409
prmt3
protein arginine methyltransferase 3
chr23_+_4741543 0.68 ENSDART00000144761
raf1a
Raf-1 proto-oncogene, serine/threonine kinase a
chr17_+_12658411 0.68 ENSDART00000139918
gpn1
GPN-loop GTPase 1
chr25_-_27722614 0.68 ENSDART00000190154
zgc:153935
zgc:153935
chr4_-_77125693 0.68 ENSDART00000174256
CU467646.3

chr3_+_28860283 0.67 ENSDART00000077235
alg1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr5_-_25733745 0.67 ENSDART00000051566
zgc:101016
zgc:101016
chr23_-_31913231 0.67 ENSDART00000146852
ENSDART00000085054
mtfr2
mitochondrial fission regulator 2
chr5_-_63302944 0.67 ENSDART00000047110
gsnb
gelsolin b
chr3_-_23643751 0.67 ENSDART00000078425
ENSDART00000140264
eve1
even-skipped-like1
chr10_+_7709724 0.66 ENSDART00000097670
ggcx
gamma-glutamyl carboxylase
chr5_-_26765188 0.66 ENSDART00000029450
rnf181
ring finger protein 181
chr14_+_24845941 0.65 ENSDART00000187513
arhgef37
Rho guanine nucleotide exchange factor (GEF) 37
chr16_-_28268201 0.65 ENSDART00000121671
ENSDART00000141911
si:dkey-12j5.1
si:dkey-12j5.1
chr4_-_72296520 0.64 ENSDART00000182638
si:cabz01071911.3
si:cabz01071911.3
chr19_-_32914227 0.64 ENSDART00000186115
ENSDART00000124246
mtdha
metadherin a
chr7_+_17816006 0.64 ENSDART00000080834
eml3
echinoderm microtubule associated protein like 3
chr10_-_21362071 0.63 ENSDART00000125167
avd
avidin
chr7_+_38936132 0.63 ENSDART00000173945
creb3l1
cAMP responsive element binding protein 3-like 1
chr23_+_44236281 0.62 ENSDART00000149842
MEPCE
si:ch1073-157b13.1
chr10_-_21362320 0.62 ENSDART00000189789
avd
avidin
chr5_+_63302660 0.61 ENSDART00000142131
si:ch73-376l24.2
si:ch73-376l24.2
chr17_-_22324727 0.61 ENSDART00000160341
CU104709.1

chr18_-_20458840 0.61 ENSDART00000177125
kif23
kinesin family member 23
chr22_-_10440688 0.61 ENSDART00000111962
nol8
nucleolar protein 8
chr7_+_33132074 0.61 ENSDART00000073554
zgc:153219
zgc:153219
chr5_-_14326959 0.60 ENSDART00000137355
tet3
tet methylcytosine dioxygenase 3
chr2_-_55298075 0.60 ENSDART00000186404
ENSDART00000149062
rab8a
RAB8A, member RAS oncogene family
chr2_+_56213694 0.60 ENSDART00000162582
upf1
upf1 regulator of nonsense transcripts homolog (yeast)
chr3_+_30922947 0.59 ENSDART00000184060
cldni
claudin i
chr8_+_25145464 0.59 ENSDART00000136505
gnai3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr8_+_48484455 0.59 ENSDART00000122737
PRDM16
si:ch211-263k4.2
chr8_-_37249813 0.59 ENSDART00000098634
ENSDART00000140233
ENSDART00000061328
rbm39b
RNA binding motif protein 39b
chr17_+_24722646 0.59 ENSDART00000138356
mtfr1l
mitochondrial fission regulator 1-like
chr23_+_11285662 0.59 ENSDART00000111028
chl1a
cell adhesion molecule L1-like a
chr18_-_25568994 0.58 ENSDART00000133029
si:ch211-13k12.2
si:ch211-13k12.2
chr16_-_28878080 0.58 ENSDART00000149501
si:dkey-239n17.4
si:dkey-239n17.4
chr24_-_4450238 0.58 ENSDART00000066835
fzd8a
frizzled class receptor 8a
chr3_+_13624815 0.58 ENSDART00000161451
pglyrp6
peptidoglycan recognition protein 6
chr22_-_36996856 0.58 ENSDART00000165923
ATP11B
si:dkey-211e20.10
chr24_-_34680956 0.58 ENSDART00000171009
ctnna1
catenin (cadherin-associated protein), alpha 1
chr20_+_34671386 0.57 ENSDART00000152836
ENSDART00000138226
elp3
elongator acetyltransferase complex subunit 3
chr25_+_16116740 0.57 ENSDART00000139778
far1
fatty acyl CoA reductase 1
chr17_-_23446760 0.57 ENSDART00000104715
pcgf5a
polycomb group ring finger 5a
chr5_-_50781623 0.57 ENSDART00000114950
zgc:194908
zgc:194908
chr9_-_20372977 0.57 ENSDART00000113418
igsf3
immunoglobulin superfamily, member 3
chr23_+_44374041 0.57 ENSDART00000136056
ephb4b
eph receptor B4b
chr9_-_31278048 0.57 ENSDART00000022204
zic5
zic family member 5 (odd-paired homolog, Drosophila)
chr24_-_26981848 0.56 ENSDART00000183198
stag1b
stromal antigen 1b
chr14_-_33481428 0.56 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lamp2
lysosomal-associated membrane protein 2
chr12_-_3077395 0.56 ENSDART00000002867
ENSDART00000126315
rfng
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr4_-_16833518 0.56 ENSDART00000179867
ldhba
lactate dehydrogenase Ba
chr13_+_30903816 0.56 ENSDART00000191727
ercc6
excision repair cross-complementation group 6
chr19_-_3742472 0.56 ENSDART00000162132
btr22
bloodthirsty-related gene family, member 22
chr2_+_6253246 0.56 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr21_+_34088377 0.55 ENSDART00000170070
mtmr1b
myotubularin related protein 1b
chr8_-_23612462 0.55 ENSDART00000025024
slc38a5b
solute carrier family 38, member 5b
chr11_-_34219211 0.55 ENSDART00000098472
tmem44
transmembrane protein 44
chr16_+_9400661 0.55 ENSDART00000146174
ice1
KIAA0947-like (H. sapiens)
chr17_-_25649079 0.55 ENSDART00000130955
ppp1cb
protein phosphatase 1, catalytic subunit, beta isozyme
chr5_+_40837539 0.55 ENSDART00000188279
si:dkey-3h3.3
si:dkey-3h3.3
chr1_-_26444075 0.55 ENSDART00000125690
ints12
integrator complex subunit 12
chr20_-_9095105 0.54 ENSDART00000140792
oma1
OMA1 zinc metallopeptidase
chr20_-_48898371 0.54 ENSDART00000170617
xrn2
5'-3' exoribonuclease 2
chr23_+_42254960 0.54 ENSDART00000102980
zcchc11
zinc finger, CCHC domain containing 11
chr1_+_40613297 0.54 ENSDART00000040798
ENSDART00000168067
ENSDART00000130490
naa15b
N(alpha)-acetyltransferase 15, NatA auxiliary subunit b
chr3_+_45365098 0.54 ENSDART00000052746
ENSDART00000156555
ube2ia
ubiquitin-conjugating enzyme E2Ia
chr16_-_17347727 0.53 ENSDART00000144392
zyx
zyxin
chr25_-_27722309 0.53 ENSDART00000148121
zgc:153935
zgc:153935
chr3_+_22035863 0.53 ENSDART00000177169
cdc27
cell division cycle 27
chr15_-_34930727 0.52 ENSDART00000179723
dhx16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr22_+_37631234 0.52 ENSDART00000007346
psmd1
proteasome 26S subunit, non-ATPase 1
chr7_+_17816470 0.52 ENSDART00000173807
eml3
echinoderm microtubule associated protein like 3
chr10_-_44482911 0.52 ENSDART00000085556
hip1ra
huntingtin interacting protein 1 related a
chr18_-_18875308 0.51 ENSDART00000127182
arl2bp
ADP-ribosylation factor-like 2 binding protein
chr16_+_16969060 0.51 ENSDART00000182819
ENSDART00000191876
si:ch211-120k19.1
rpl18
si:ch211-120k19.1
ribosomal protein L18
chr5_-_11809710 0.51 ENSDART00000186998
ENSDART00000181363
ENSDART00000180681
nf2a
neurofibromin 2a (merlin)
chr11_+_24703108 0.51 ENSDART00000159173
gpr25
G protein-coupled receptor 25
chr24_+_5237753 0.51 ENSDART00000106488
ENSDART00000005901
plod2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr20_+_46513651 0.51 ENSDART00000152977
zc3h14
zinc finger CCCH-type containing 14
chr6_+_40922572 0.51 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr19_+_30884706 0.51 ENSDART00000052126
yars
tyrosyl-tRNA synthetase
chr7_+_7511914 0.50 ENSDART00000172848
clcn3
chloride channel 3
chr11_+_31864921 0.50 ENSDART00000180252
diaph3
diaphanous-related formin 3
chr6_+_50393047 0.50 ENSDART00000055502
ENSDART00000055511
ergic3
ERGIC and golgi 3
chr23_-_20345473 0.49 ENSDART00000140935
si:rp71-17i16.6
si:rp71-17i16.6
chr15_+_7086327 0.49 ENSDART00000114560
pik3cb
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr21_+_25802190 0.49 ENSDART00000128987
nf2b
neurofibromin 2b (merlin)
chr15_+_34988148 0.49 ENSDART00000076269
ccdc105
coiled-coil domain containing 105
chr6_-_35046735 0.49 ENSDART00000143649
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr21_-_26028205 0.49 ENSDART00000034875
sdf2
stromal cell-derived factor 2
chr8_+_41037541 0.48 ENSDART00000129344
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr20_-_38787047 0.48 ENSDART00000152913
ENSDART00000153430
dnajc5ga
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a
chr4_+_11723852 0.48 ENSDART00000028820
mkln1
muskelin 1, intracellular mediator containing kelch motifs
chr6_+_20647155 0.47 ENSDART00000193477
slc19a1
solute carrier family 19 (folate transporter), member 1
chr11_-_30158191 0.47 ENSDART00000155278
ENSDART00000156121
scml2
Scm polycomb group protein like 2
chr7_+_67749251 0.47 ENSDART00000167562
dhx38
DEAH (Asp-Glu-Ala-His) box polypeptide 38
chr12_-_42214 0.47 ENSDART00000045071
foxk2
forkhead box K2
chr2_+_27010439 0.47 ENSDART00000030547
cdh7a
cadherin 7a
chr2_-_59145027 0.47 ENSDART00000128320
FO834803.1

chr25_+_35553542 0.47 ENSDART00000113723
spi1a
Spi-1 proto-oncogene a
chr13_+_36923052 0.46 ENSDART00000026313
tmx1
thioredoxin-related transmembrane protein 1
chr18_+_20560616 0.46 ENSDART00000136710
ENSDART00000151974
ENSDART00000121699
ENSDART00000040074
wee2
WEE1 homolog 2 (S. pombe)
chr4_+_69559692 0.46 ENSDART00000164383
znf993
zinc finger protein 993
chr20_-_54924593 0.46 ENSDART00000151522
si:dkey-15f23.1
si:dkey-15f23.1

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxb2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0000012 single strand break repair(GO:0000012)
0.5 2.0 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.4 1.1 GO:0048785 hatching gland development(GO:0048785)
0.4 1.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.3 1.4 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.3 1.7 GO:0046083 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.3 1.4 GO:0030224 monocyte differentiation(GO:0030224)
0.3 1.0 GO:0061317 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.3 1.1 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.3 0.8 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.2 1.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.2 0.9 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.2 0.9 GO:0021742 abducens nucleus development(GO:0021742)
0.2 3.4 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.2 1.0 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.2 1.0 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.2 1.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.2 0.6 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531) eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.2 0.6 GO:0098581 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.2 0.6 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.2 0.5 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.2 0.5 GO:0098838 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.2 0.6 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 1.3 GO:0060118 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.1 0.4 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.1 1.2 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 1.3 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.1 1.0 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.1 0.6 GO:1902024 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.5 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 0.4 GO:0046104 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.5 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.1 0.6 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.1 1.1 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1 1.0 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.1 0.7 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 1.2 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 0.8 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 1.3 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.1 1.6 GO:0001757 somite specification(GO:0001757) segment specification(GO:0007379)
0.1 0.6 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.3 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.6 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 0.6 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.5 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 0.5 GO:0061055 myotome development(GO:0061055)
0.1 0.4 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.9 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.3 GO:0061549 sympathetic ganglion development(GO:0061549)
0.1 1.3 GO:0031297 replication fork processing(GO:0031297)
0.1 0.3 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.5 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 4.6 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.1 0.7 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.1 0.5 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.1 0.8 GO:0051382 kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.1 1.0 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 0.7 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.7 GO:0060236 regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224)
0.1 1.7 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.1 1.0 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 1.1 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.1 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.8 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 1.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.6 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.9 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.7 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.3 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.0 0.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 1.6 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.3 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.0 0.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.6 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0 0.2 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.0 0.9 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.5 GO:0072595 maintenance of protein localization in organelle(GO:0072595)
0.0 0.6 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.5 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 1.0 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.1 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.2 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.3 GO:0097300 necrotic cell death(GO:0070265) programmed necrotic cell death(GO:0097300)
0.0 0.2 GO:0036268 swimming(GO:0036268)
0.0 0.3 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.4 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 1.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.4 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.2 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.8 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.4 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.4 GO:0007340 acrosome reaction(GO:0007340)
0.0 1.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.9 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.4 GO:0060173 limb development(GO:0060173)
0.0 0.8 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 1.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.7 GO:0051014 actin filament severing(GO:0051014)
0.0 0.5 GO:0060034 notochord cell differentiation(GO:0060034)
0.0 0.2 GO:0071451 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 1.0 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.9 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 2.2 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.0 0.4 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.6 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 1.6 GO:0034504 protein localization to nucleus(GO:0034504)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.4 GO:0002761 regulation of myeloid leukocyte differentiation(GO:0002761)
0.0 0.7 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.5 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.1 GO:0046462 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0032689 negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.3 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.3 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.5 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.1 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.0 1.4 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.7 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.6 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.4 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.6 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.3 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.0 0.6 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.4 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 0.4 GO:0000281 mitotic cytokinesis(GO:0000281)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 1.1 GO:0070724 BMP receptor complex(GO:0070724)
0.2 0.6 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.2 1.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 0.7 GO:0005880 nuclear microtubule(GO:0005880)
0.2 0.5 GO:0034515 proteasome storage granule(GO:0034515)
0.2 1.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 1.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.3 GO:0005682 U5 snRNP(GO:0005682)
0.1 1.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.5 GO:0043186 P granule(GO:0043186)
0.0 1.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.3 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 1.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.9 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 2.1 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.6 GO:0008278 cohesin complex(GO:0008278)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818)
0.0 2.4 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0030496 midbody(GO:0030496)
0.0 0.6 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.5 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 3.2 GO:0005730 nucleolus(GO:0005730)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0072546 ER membrane protein complex(GO:0072546)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.2 1.2 GO:0009374 biotin binding(GO:0009374)
0.2 0.9 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.2 0.6 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.2 1.7 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.2 2.0 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.2 0.5 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.2 0.7 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.2 0.5 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.2 1.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.6 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.5 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 1.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.2 GO:0043515 kinetochore binding(GO:0043515)
0.1 1.4 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.7 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.1 0.5 GO:0060182 apelin receptor activity(GO:0060182)
0.1 0.3 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.5 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.1 1.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.6 GO:0070888 E-box binding(GO:0070888)
0.1 0.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.6 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 1.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.4 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.1 0.6 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.5 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 2.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.2 GO:0000035 acyl binding(GO:0000035)
0.1 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 1.0 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 1.0 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.9 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.5 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.5 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 1.0 GO:0032190 acrosin binding(GO:0032190)
0.1 1.0 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.6 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.7 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.4 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 2.7 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.4 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.7 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 1.0 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 1.9 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.3 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.6 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 1.1 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.9 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.2 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.0 0.1 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 1.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.5 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.0 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 1.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 3.4 GO:0042393 histone binding(GO:0042393)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.0 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.0 0.1 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.4 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 1.5 GO:0045296 cadherin binding(GO:0045296)
0.0 1.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.6 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.8 ST GA13 PATHWAY G alpha 13 Pathway
0.0 1.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.5 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.3 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.0 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 0.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.4 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.1 1.0 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 3.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.9 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.2 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.5 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.0 REACTOME TRAF6 MEDIATED INDUCTION OF NFKB AND MAP KINASES UPON TLR7 8 OR 9 ACTIVATION Genes involved in TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism