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PRJEB1986: zebrafish developmental stages transcriptome

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Results for hoxc12a+hoxc12b

Z-value: 1.15

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Transcription factors associated with hoxc12a+hoxc12b

Gene Symbol Gene ID Gene Info
hoxc12a
ENSDARG00000070352 homeobox C12a
hoxc12b
ENSDARG00000103133 homeobox C12b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc12bdr11_v1_chr11_+_2172335_21723350.734.4e-04Click!
hoxc12adr11_v1_chr23_+_36063599_360635990.361.3e-01Click!

Activity profile of hoxc12a+hoxc12b motif

Sorted Z-values of hoxc12a+hoxc12b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_20715020 4.82 ENSDART00000015224
gadd45gb.1
growth arrest and DNA-damage-inducible, gamma b, tandem duplicate 1
chr23_+_36087219 3.45 ENSDART00000154825
hoxc3a
homeobox C3a
chr12_+_27129659 3.22 ENSDART00000076161
hoxb5b
homeobox B5b
chr19_+_7424347 2.74 ENSDART00000004622
sf3b4
splicing factor 3b, subunit 4
chr2_-_17114852 2.74 ENSDART00000006549
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr11_+_2198831 2.62 ENSDART00000160515
hoxc6b
homeobox C6b
chr14_+_32022272 2.58 ENSDART00000105760
zic6
zic family member 6
chr15_+_29116063 2.58 ENSDART00000016112
ENSDART00000153609
ENSDART00000155630
capns1b
calpain, small subunit 1 b
chr17_+_21295132 2.56 ENSDART00000103845
eno4
enolase family member 4
chr3_-_49382896 2.50 ENSDART00000169115
si:ch73-167f10.1
si:ch73-167f10.1
chr16_+_20910186 2.49 ENSDART00000046766
hoxa10b
homeobox A10b
chr16_-_6205790 2.46 ENSDART00000038495
ctnnb1
catenin (cadherin-associated protein), beta 1
chr19_+_19762183 2.39 ENSDART00000163611
ENSDART00000187604
hoxa3a
homeobox A3a
chr25_+_3294150 2.39 ENSDART00000030683
tmpob
thymopoietin b
chr17_+_17764979 2.30 ENSDART00000105013
alkbh1
alkB homolog 1, histone H2A dioxygenase
chr21_+_13128180 2.22 ENSDART00000081426
odf2a
outer dense fiber of sperm tails 2a
chr21_-_22357985 2.17 ENSDART00000101751
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr2_-_6065416 2.14 ENSDART00000037698
uck2b
uridine-cytidine kinase 2b
chr5_-_24542726 2.02 ENSDART00000182975
trmt2a
tRNA methyltransferase 2 homolog A
chr3_+_23710839 1.96 ENSDART00000151584
hoxb4a
homeobox B4a
chr3_+_23691847 1.95 ENSDART00000078453
hoxb7a
homeobox B7a
chr23_-_28025943 1.86 ENSDART00000181146
sp5l
Sp5 transcription factor-like
chr6_+_40775800 1.75 ENSDART00000085090
si:ch211-157b11.8
si:ch211-157b11.8
chr16_-_12060488 1.75 ENSDART00000188733
si:ch211-69g19.2
si:ch211-69g19.2
chr2_-_20715094 1.73 ENSDART00000155439
dusp12
dual specificity phosphatase 12
chr3_+_31058464 1.72 ENSDART00000153381
si:dkey-66i24.7
si:dkey-66i24.7
chr4_-_13995766 1.71 ENSDART00000147955
prickle1b
prickle homolog 1b
chr11_-_37717709 1.67 ENSDART00000177280
yod1
YOD1 deubiquitinase
chr3_-_40254634 1.66 ENSDART00000154562
top3a
DNA topoisomerase III alpha
chr5_-_31857345 1.64 ENSDART00000112546
pkn3
protein kinase N3
chr7_+_10563017 1.63 ENSDART00000193520
ENSDART00000173125
zfand6
zinc finger, AN1-type domain 6
chr6_-_9236309 1.61 ENSDART00000160397
ENSDART00000164603
iqcb1
IQ motif containing B1
chr9_-_29039506 1.61 ENSDART00000100744
tmem177
transmembrane protein 177
chr12_-_17199381 1.60 ENSDART00000193292
lipf
lipase, gastric
chr25_-_7670391 1.60 ENSDART00000044970
bet1l
Bet1 golgi vesicular membrane trafficking protein-like
chr22_+_10646928 1.58 ENSDART00000038465
rassf1
Ras association (RalGDS/AF-6) domain family 1
chr20_+_48803248 1.56 ENSDART00000164006
nkx2.4b
NK2 homeobox 4b
chr24_+_21540842 1.55 ENSDART00000091529
wasf3b
WAS protein family, member 3b
chr2_-_22966076 1.55 ENSDART00000143412
ENSDART00000146014
ENSDART00000183443
ENSDART00000191056
ENSDART00000183539
sap130b
Sin3A-associated protein b
chr16_+_11242443 1.54 ENSDART00000024935
gsk3ab
glycogen synthase kinase 3 alpha b
chr16_+_5898878 1.53 ENSDART00000180930
ulk4
unc-51 like kinase 4
chr1_-_38171648 1.51 ENSDART00000137451
ENSDART00000047159
hmgb2a
high mobility group box 2a
chr6_-_28943056 1.47 ENSDART00000065138
tbc1d23
TBC1 domain family, member 23
chr5_-_31856681 1.47 ENSDART00000187817
pkn3
protein kinase N3
chr5_+_41477954 1.46 ENSDART00000185871
pias2
protein inhibitor of activated STAT, 2
chr6_+_27992886 1.44 ENSDART00000160354
amotl2a
angiomotin like 2a
chr16_+_42471455 1.42 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr19_+_26640096 1.42 ENSDART00000067793
ints3
integrator complex subunit 3
chr14_-_26425416 1.40 ENSDART00000088690
lman2
lectin, mannose-binding 2
chr19_+_19761966 1.39 ENSDART00000163697
hoxa3a
homeobox A3a
chr6_-_14038804 1.33 ENSDART00000184606
ENSDART00000184609
etv5b
ets variant 5b
chr7_-_30624435 1.31 ENSDART00000173828
rnf111
ring finger protein 111
chr13_-_25196758 1.30 ENSDART00000184722
adka
adenosine kinase a
chr9_+_22634073 1.30 ENSDART00000181822
etv5a
ets variant 5a
chr6_-_53334259 1.27 ENSDART00000172465
gnb1b
guanine nucleotide binding protein (G protein), beta polypeptide 1b
chr16_+_10429770 1.25 ENSDART00000173132
vars
valyl-tRNA synthetase
chr22_+_10543329 1.25 ENSDART00000091850
atrip
ATR interacting protein
chr6_-_34838397 1.25 ENSDART00000060169
ENSDART00000169605
mier1a
mesoderm induction early response 1a, transcriptional regulator
chr24_-_24797455 1.24 ENSDART00000138741
pde7a
phosphodiesterase 7A
chr12_-_26851726 1.24 ENSDART00000047724
zeb1b
zinc finger E-box binding homeobox 1b
chr15_-_6863150 1.23 ENSDART00000153815
meis3
myeloid ecotropic viral integration site 3
chr7_+_46019780 1.23 ENSDART00000163991
ccne1
cyclin E1
chr5_-_30715225 1.22 ENSDART00000016758
ftr82
finTRIM family, member 82
chr13_+_29925397 1.21 ENSDART00000123482
cuedc2
CUE domain containing 2
chr23_+_33752275 1.21 ENSDART00000007260
si:ch211-210c8.6
si:ch211-210c8.6
chr22_+_10440991 1.21 ENSDART00000064805
cenpp
centromere protein P
chr6_+_27991943 1.19 ENSDART00000143974
ENSDART00000141354
ENSDART00000088914
ENSDART00000139367
amotl2a
angiomotin like 2a
chr19_+_30884960 1.18 ENSDART00000140603
ENSDART00000183224
ENSDART00000135484
ENSDART00000139599
yars
tyrosyl-tRNA synthetase
chr21_-_43131752 1.18 ENSDART00000024137
p4ha2
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2
chr6_+_3730843 1.17 ENSDART00000019630
FO704755.1

chr18_-_31105391 1.14 ENSDART00000039495
pdcd5
programmed cell death 5
chr5_-_69499486 1.12 ENSDART00000023983
ENSDART00000180293
psat1
phosphoserine aminotransferase 1
chr2_+_31330358 1.12 ENSDART00000178066
clul1
clusterin-like 1 (retinal)
chr6_-_3992942 1.11 ENSDART00000182328
unc50
unc-50 homolog (C. elegans)
chr1_-_29061285 1.10 ENSDART00000053933
ENSDART00000142350
ENSDART00000192615
gemin8
gem (nuclear organelle) associated protein 8
chr7_-_18508815 1.09 ENSDART00000173539
rgs12a
regulator of G protein signaling 12a
chr19_+_5315987 1.09 ENSDART00000145749
si:dkeyp-113d7.1
si:dkeyp-113d7.1
chr18_+_18000887 1.08 ENSDART00000147797
si:ch211-212o1.2
si:ch211-212o1.2
chr10_-_31805923 1.08 ENSDART00000077785
vps26bl
vacuolar protein sorting 26 homolog B, like
chr11_-_6880725 1.08 ENSDART00000007204
ddx49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr23_+_8797143 1.04 ENSDART00000132992
sox18
SRY (sex determining region Y)-box 18
chr6_-_53281518 1.04 ENSDART00000157621
rbm5
RNA binding motif protein 5
chr12_-_28910419 1.03 ENSDART00000153278
ENSDART00000152937
CCDC189
si:ch73-81k8.2
chr9_+_38314466 1.00 ENSDART00000048753
ddx18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr6_+_49551614 1.00 ENSDART00000022581
rab22a
RAB22A, member RAS oncogene family
chr15_+_5132439 1.00 ENSDART00000010350
pgm2l1
phosphoglucomutase 2-like 1
chr3_-_18737126 0.99 ENSDART00000055767
e4f1
E4F transcription factor 1
chr13_-_3936555 0.98 ENSDART00000017052
ncoa4
nuclear receptor coactivator 4
chr24_-_31223232 0.96 ENSDART00000164155
alg14
ALG14, UDP-N-acetylglucosaminyltransferase subunit
chr3_+_23707691 0.96 ENSDART00000025449
hoxb5a
homeobox B5a
chr13_-_24447332 0.95 ENSDART00000043004
slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr5_-_54395488 0.94 ENSDART00000160781
zmynd19
zinc finger, MYND-type containing 19
chr18_-_21748808 0.93 ENSDART00000079253
pskh1
protein serine kinase H1
chr5_-_26764298 0.90 ENSDART00000189373
rnf181
ring finger protein 181
chr18_+_3140682 0.90 ENSDART00000166382
clns1a
chloride channel, nucleotide-sensitive, 1A
chr17_+_42274825 0.89 ENSDART00000020156
pax1a
paired box 1a
chr11_-_36051004 0.89 ENSDART00000025033
gpx1a
glutathione peroxidase 1a
chr16_-_10316359 0.89 ENSDART00000104025
flot1b
flotillin 1b
chr7_-_25133783 0.88 ENSDART00000173781
ENSDART00000121943
ENSDART00000077219
badb
BCL2 associated agonist of cell death b
chr18_-_21685055 0.88 ENSDART00000019861
mbtps1
membrane-bound transcription factor peptidase, site 1
chr3_-_15734358 0.87 ENSDART00000137325
mvp
major vault protein
chr2_+_23039041 0.86 ENSDART00000056921
csnk1g2a
casein kinase 1, gamma 2a
chr22_+_2403068 0.86 ENSDART00000132925
ENSDART00000132569
zgc:112977
zgc:112977
chr7_+_30240791 0.85 ENSDART00000109243
sema4bb
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Bb
chr14_-_32866351 0.84 ENSDART00000166133
ENSDART00000172545
ube2a
ubiquitin-conjugating enzyme E2A (RAD6 homolog)
chr7_+_29167744 0.84 ENSDART00000076345
slc38a8b
solute carrier family 38, member 8b
chr2_-_37134169 0.83 ENSDART00000146123
ENSDART00000146533
ENSDART00000040427
elavl1a
ELAV like RNA binding protein 1a
chr3_+_36284986 0.82 ENSDART00000059533
wipi1
WD repeat domain, phosphoinositide interacting 1
chr4_-_28958601 0.80 ENSDART00000111294
zgc:174315
zgc:174315
chr14_-_36862745 0.77 ENSDART00000109293
rnf130
ring finger protein 130
chr22_-_10440688 0.76 ENSDART00000111962
nol8
nucleolar protein 8
chr15_-_28262632 0.76 ENSDART00000134601
ENSDART00000175022
prpf8
pre-mRNA processing factor 8
chr3_+_11072958 0.75 ENSDART00000158899
mrps7
mitochondrial ribosomal protein S7
chr20_+_34671386 0.75 ENSDART00000152836
ENSDART00000138226
elp3
elongator acetyltransferase complex subunit 3
chr8_-_16788626 0.72 ENSDART00000191652
CR759968.2

chr10_-_36825984 0.72 ENSDART00000111104
phf12a
PHD finger protein 12a
chr15_+_27387555 0.71 ENSDART00000018603
tbx4
T-box 4
chr4_-_69127091 0.71 ENSDART00000136092
si:ch211-209j12.3
si:ch211-209j12.3
chr22_+_17192767 0.71 ENSDART00000130810
ENSDART00000183006
atpaf1
ATP synthase mitochondrial F1 complex assembly factor 1
chr13_+_33268657 0.70 ENSDART00000002095
tmem39b
transmembrane protein 39B
chr16_-_47426482 0.69 ENSDART00000148631
ENSDART00000149723
sept7b
septin 7b
chr5_+_32490238 0.68 ENSDART00000191839
ndor1
NADPH dependent diflavin oxidoreductase 1
chr16_-_16761164 0.68 ENSDART00000135872
si:dkey-27n14.1
si:dkey-27n14.1
chrM_+_3803 0.67 ENSDART00000093596
mt-nd1
NADH dehydrogenase 1, mitochondrial
chr12_-_10038870 0.67 ENSDART00000152250
ngfrb
nerve growth factor receptor b
chr4_-_73488406 0.65 ENSDART00000115002
si:ch73-266f23.1
si:ch73-266f23.1
chr19_-_33370271 0.65 ENSDART00000132628
nkd3l
naked cuticle homolog 3, like
chr23_+_23658474 0.65 ENSDART00000162838
agrn
agrin
chr24_-_24796583 0.65 ENSDART00000144791
ENSDART00000146570
pde7a
phosphodiesterase 7A
chr20_-_19530751 0.65 ENSDART00000148574
eif2b4
eukaryotic translation initiation factor 2B, subunit 4 delta
chr18_+_16943911 0.62 ENSDART00000157609
si:dkey-8l13.5
si:dkey-8l13.5
chr22_+_10676981 0.61 ENSDART00000138016
hyal2b
hyaluronoglucosaminidase 2b
chr13_+_45431660 0.61 ENSDART00000099950
syf2
SYF2 pre-mRNA-splicing factor
chr17_+_23255365 0.61 ENSDART00000180277
AL935174.5

chr7_-_23873173 0.60 ENSDART00000101408
zgc:162171
zgc:162171
chr12_-_9123352 0.59 ENSDART00000149655
adam8b
ADAM metallopeptidase domain 8b
chr14_-_28052474 0.59 ENSDART00000172948
ENSDART00000135337
TSC22D3 (1 of many)
zgc:64189
si:ch211-220e11.3
zgc:64189
chr25_-_7670616 0.58 ENSDART00000131583
ENSDART00000142794
bet1l
Bet1 golgi vesicular membrane trafficking protein-like
chr13_+_39182099 0.58 ENSDART00000131434
fam135a
family with sequence similarity 135, member A
chr5_-_32489796 0.58 ENSDART00000168870
gpr107
G protein-coupled receptor 107
chr23_-_39849155 0.58 ENSDART00000115330
ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr20_+_38837238 0.58 ENSDART00000061334
ift172
intraflagellar transport 172
chr15_-_1590858 0.55 ENSDART00000081875
nnr
nanor
chr15_+_34675660 0.54 ENSDART00000009127
lta
lymphotoxin alpha (TNF superfamily, member 1)
chr10_+_26612321 0.54 ENSDART00000134322
fhl1b
four and a half LIM domains 1b
chr21_+_4540127 0.53 ENSDART00000043431
nup188
nucleoporin 188
chr24_+_25913162 0.52 ENSDART00000143099
ENSDART00000184814
map3k15
mitogen-activated protein kinase kinase kinase 15
chr8_+_26293673 0.51 ENSDART00000144977
mgll
monoglyceride lipase
chr1_-_22834824 0.51 ENSDART00000043556
ldb2b
LIM domain binding 2b
chr8_+_23861461 0.51 ENSDART00000037109
srpk1a
SRSF protein kinase 1a
chr2_-_39759059 0.50 ENSDART00000007333
slc25a36a
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36a
chr12_+_2677303 0.49 ENSDART00000093113
antxr1c
anthrax toxin receptor 1c
chr3_+_24190207 0.49 ENSDART00000034762
prr15la
proline rich 15-like a
chr3_-_10749691 0.47 ENSDART00000183088
CU210890.1

chr11_-_1550709 0.46 ENSDART00000110097
si:ch73-303b9.1
si:ch73-303b9.1
chr23_+_36115541 0.45 ENSDART00000130090
hoxc6a
homeobox C6a
chr1_+_31019165 0.43 ENSDART00000102210
itga6b
integrin, alpha 6b
chr1_+_58424507 0.42 ENSDART00000114197
si:ch73-236c18.3
si:ch73-236c18.3
chr20_-_23656516 0.42 ENSDART00000149735
cbr4
carbonyl reductase 4
chr16_-_31452416 0.41 ENSDART00000140880
ENSDART00000008297
ENSDART00000147373
csnk2a1
casein kinase 2, alpha 1 polypeptide
chr18_+_33264609 0.40 ENSDART00000050639
v2ra20
vomeronasal 2 receptor, a20
chr16_-_33806390 0.37 ENSDART00000160671
rspo1
R-spondin 1
chr18_+_41542542 0.37 ENSDART00000087445
tsen34
TSEN34 tRNA splicing endonuclease subunit
chr2_+_20406399 0.36 ENSDART00000006817
ENSDART00000137848
palmda
palmdelphin a
chr20_-_23657304 0.33 ENSDART00000016913
cbr4
carbonyl reductase 4
chr4_-_30712588 0.33 ENSDART00000142393
si:dkey-16p19.5
si:dkey-16p19.5
chr2_-_37874647 0.32 ENSDART00000039386
zgc:66427
zgc:66427
chr15_-_23942861 0.31 ENSDART00000002824
appbp2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr2_+_20410652 0.31 ENSDART00000185940
palmda
palmdelphin a
chr11_+_24716837 0.31 ENSDART00000145217
zgc:153953
zgc:153953
chr6_-_57476465 0.29 ENSDART00000128065
ddx27
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chr12_-_30777540 0.29 ENSDART00000126466
entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr1_-_44638058 0.29 ENSDART00000081835
slc43a1b
solute carrier family 43 (amino acid system L transporter), member 1b
chr15_-_39820491 0.26 ENSDART00000097134
robo1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr6_+_13207139 0.26 ENSDART00000185601
ENSDART00000182182
ino80db
INO80 complex subunit Db
chr7_-_43840418 0.25 ENSDART00000174592
cdh11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr1_+_36612660 0.24 ENSDART00000190784
ednraa
endothelin receptor type Aa
chr9_-_19161982 0.24 ENSDART00000081878
pou1f1
POU class 1 homeobox 1
chr18_+_7456888 0.23 ENSDART00000081468
terb1
telomere repeat binding bouquet formation protein 1
chr11_+_6881001 0.22 ENSDART00000170331
klhl26
kelch-like family member 26
chr19_+_26718074 0.22 ENSDART00000134455
zgc:100906
zgc:100906
chr13_+_8892784 0.21 ENSDART00000075054
ENSDART00000143705
thada
thyroid adenoma associated
chr16_+_38659475 0.20 ENSDART00000023238
emc2
ER membrane protein complex subunit 2
chr13_-_18119696 0.18 ENSDART00000148125
washc2c
WASH complex subunit 2C
chr11_-_18557929 0.16 ENSDART00000110882
ENSDART00000181381
ENSDART00000189312
dido1
death inducer-obliterator 1
chr5_+_17624463 0.16 ENSDART00000183869
ENSDART00000081064
fbrsl1
fibrosin-like 1
chr5_-_9216758 0.15 ENSDART00000134896
ENSDART00000147000
lrp13
low-density lipoprotein receptor related-protein 13
chr4_-_38259998 0.15 ENSDART00000172389
znf1093
zinc finger protein 1093
chr2_-_55797318 0.14 ENSDART00000158147
calr3b
calreticulin 3b
chr24_-_21913426 0.13 ENSDART00000081178
c1qtnf9
C1q and TNF related 9
chr14_-_36863432 0.11 ENSDART00000158052
rnf130
ring finger protein 130
chr13_+_21768447 0.11 ENSDART00000100941
chchd1
coiled-coil-helix-coiled-coil-helix domain containing 1
chr15_+_37954666 0.10 ENSDART00000126534
ENSDART00000155548
si:dkey-238d18.7
si:dkey-238d18.7
chr24_+_34069675 0.10 ENSDART00000143995
si:ch211-190p8.2
si:ch211-190p8.2
chr7_+_59739164 0.10 ENSDART00000110412
gpr78b
G protein-coupled receptor 78b
chr9_-_39005317 0.09 ENSDART00000014207
myl1
myosin, light chain 1, alkali; skeletal, fast
chr6_-_28222592 0.09 ENSDART00000131126
bcl6a
B-cell CLL/lymphoma 6a (zinc finger protein 51)
chr3_+_16663373 0.07 ENSDART00000100961
zgc:55558
zgc:55558
chr15_-_2754056 0.07 ENSDART00000129380
ppp5c
protein phosphatase 5, catalytic subunit
chr12_+_46696867 0.06 ENSDART00000152928
ENSDART00000153445
ENSDART00000123357
ENSDART00000152880
ENSDART00000123834
ENSDART00000174765
ENSDART00000189923
exoc7
exocyst complex component 7

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc12a+hoxc12b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.5 3.8 GO:0060017 parathyroid gland development(GO:0060017)
0.5 4.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.5 1.5 GO:1990403 embryonic brain development(GO:1990403)
0.5 2.3 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.4 1.7 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.4 1.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.3 2.6 GO:0035912 establishment of cell polarity involved in ameboidal cell migration(GO:0003365) aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.3 2.6 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.3 0.9 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.3 2.1 GO:0044211 CTP salvage(GO:0044211)
0.2 0.7 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.2 1.2 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.2 1.2 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.2 0.7 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 3.2 GO:0010002 cardioblast differentiation(GO:0010002)
0.2 2.7 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.2 3.3 GO:0035108 limb morphogenesis(GO:0035108)
0.2 1.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.2 0.7 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.2 1.3 GO:0044209 AMP salvage(GO:0044209)
0.2 1.2 GO:0034080 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.2 1.6 GO:0036372 opsin transport(GO:0036372)
0.2 0.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 1.7 GO:0021535 cell migration in hindbrain(GO:0021535)
0.2 0.5 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.2 2.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.3 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 0.8 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.4 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.7 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 1.6 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.7 GO:0006265 DNA topological change(GO:0006265)
0.1 1.6 GO:0030878 thyroid gland development(GO:0030878)
0.1 1.0 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.9 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.1 1.6 GO:0021508 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.1 2.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 0.2 GO:0090220 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 1.4 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.1 1.6 GO:0072663 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1 1.9 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 0.8 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 1.9 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 1.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 2.2 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.1 1.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 1.5 GO:0038034 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.1 0.5 GO:1901998 toxin transport(GO:1901998)
0.1 3.3 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 0.4 GO:0031179 peptide modification(GO:0031179)
0.1 1.5 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.3 GO:0071405 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.0 0.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.7 GO:1901655 cellular response to ketone(GO:1901655)
0.0 0.5 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.7 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.0 1.0 GO:0060840 artery development(GO:0060840)
0.0 0.2 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.3 GO:0003262 endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262)
0.0 2.6 GO:0021510 spinal cord development(GO:0021510)
0.0 0.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 11.4 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 1.0 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.7 GO:1990798 pancreas regeneration(GO:1990798)
0.0 1.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 1.3 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 1.2 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.8 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.9 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.2 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.8 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.0 0.6 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 1.2 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 1.6 GO:0001666 response to hypoxia(GO:0001666)
0.0 1.3 GO:0034504 protein localization to nucleus(GO:0034504)
0.0 0.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.9 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.7 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.5 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 1.6 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 2.1 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.3 2.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 2.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.3 1.2 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.3 0.9 GO:0034709 methylosome(GO:0034709)
0.3 1.5 GO:0071203 WASH complex(GO:0071203)
0.2 1.4 GO:0070876 SOSS complex(GO:0070876)
0.2 0.9 GO:0016600 flotillin complex(GO:0016600)
0.2 0.6 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.2 0.8 GO:0033503 HULC complex(GO:0033503)
0.1 1.1 GO:0032797 SMN complex(GO:0032797)
0.1 0.5 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 2.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 2.3 GO:0070822 Sin3-type complex(GO:0070822)
0.1 0.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 3.8 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.1 GO:0030904 retromer complex(GO:0030904)
0.1 1.6 GO:0031209 SCAR complex(GO:0031209)
0.1 0.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.8 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.7 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.6 GO:0000974 Prp19 complex(GO:0000974)
0.1 2.7 GO:0005657 replication fork(GO:0005657)
0.0 1.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.3 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 1.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 2.6 GO:0055037 recycling endosome(GO:0055037)
0.0 2.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.2 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.0 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.7 GO:1990204 oxidoreductase complex(GO:1990204)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.5 2.7 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.4 1.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.3 2.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 2.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.3 2.1 GO:0004849 uridine kinase activity(GO:0004849)
0.3 1.3 GO:0004001 adenosine kinase activity(GO:0004001)
0.3 0.8 GO:0030623 U5 snRNA binding(GO:0030623)
0.2 1.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 0.7 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.2 0.5 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.2 0.6 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 1.7 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 3.1 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 1.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 1.4 GO:0005537 mannose binding(GO:0005537)
0.1 1.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.7 GO:0005035 death receptor activity(GO:0005035)
0.1 1.3 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 1.0 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 1.5 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.4 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 1.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 1.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.4 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.9 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 2.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 2.4 GO:0003724 RNA helicase activity(GO:0003724)
0.0 2.0 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.2 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.7 GO:0000049 tRNA binding(GO:0000049)
0.0 1.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 31.2 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 1.2 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.3 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.7 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.6 GO:0019843 rRNA binding(GO:0019843)
0.0 0.5 GO:0044325 ion channel binding(GO:0044325)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 4.8 PID P53 REGULATION PATHWAY p53 pathway
0.1 1.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.7 PID ATM PATHWAY ATM pathway
0.1 2.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.3 PID ATR PATHWAY ATR signaling pathway
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 3.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 2.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 0.9 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 3.4 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.1 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.9 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 1.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions