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PRJEB1986: zebrafish developmental stages transcriptome

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Results for hoxd11a

Z-value: 1.05

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Transcription factors associated with hoxd11a

Gene Symbol Gene ID Gene Info
hoxd11a
ENSDARG00000059267 homeobox D11a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxd11adr11_v1_chr9_-_1978090_1978090-0.831.2e-05Click!

Activity profile of hoxd11a motif

Sorted Z-values of hoxd11a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr24_-_40009446 6.55 ENSDART00000087422
aoc1
amine oxidase, copper containing 1
chr23_+_27068225 4.99 ENSDART00000054238
mipa
major intrinsic protein of lens fiber a
chr11_+_30244356 4.53 ENSDART00000036050
ENSDART00000150080
rs1a
retinoschisin 1a
chr14_-_33613794 3.90 ENSDART00000010022
xpnpep2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr24_+_402493 3.63 ENSDART00000036472
VSTM2A
zgc:110852
chr7_-_26457208 3.44 ENSDART00000173519
zgc:172079
zgc:172079
chr16_-_28658341 3.40 ENSDART00000148456
abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr24_+_40529346 3.38 ENSDART00000168548
CU929259.1

chr24_-_6158933 3.13 ENSDART00000021609
gad2
glutamate decarboxylase 2
chr2_+_21128391 2.94 ENSDART00000136814
pip4k2ab
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha b
chr17_-_15498275 2.83 ENSDART00000156905
ENSDART00000080661
si:ch211-266g18.10
si:ch211-266g18.10
chr4_-_8043839 2.74 ENSDART00000190047
ENSDART00000057567
si:ch211-240l19.5
si:ch211-240l19.5
chr22_+_31821815 2.65 ENSDART00000159825
dock3
dedicator of cytokinesis 3
chr7_+_2467057 2.65 ENSDART00000154517
si:dkey-125e8.3
si:dkey-125e8.3
chr15_+_20403903 2.63 ENSDART00000134182
cox7a1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr25_+_29161609 2.60 ENSDART00000180752
pkmb
pyruvate kinase M1/2b
chr1_+_17900306 2.53 ENSDART00000089480
cyp4v8
cytochrome P450, family 4, subfamily V, polypeptide 8
chr1_+_52481332 2.48 ENSDART00000074231
cldnd1b
claudin domain containing 1b
chr9_+_33154841 2.46 ENSDART00000132465
dopey2
dopey family member 2
chr6_-_40697585 2.38 ENSDART00000113196
si:ch211-157b11.14
si:ch211-157b11.14
chr1_-_22512063 2.32 ENSDART00000031546
ENSDART00000190987
chrna6
cholinergic receptor, nicotinic, alpha 6
chr3_+_49074008 2.32 ENSDART00000168864
zgc:112146
zgc:112146
chr24_+_5840258 2.31 ENSDART00000087034
trpc1
transient receptor potential cation channel, subfamily C, member 1
chr8_+_52637507 2.26 ENSDART00000163830
si:dkey-90l8.3
si:dkey-90l8.3
chr21_+_11969603 2.10 ENSDART00000142247
ENSDART00000140652
mlnl
motilin-like
chr2_+_2223837 2.02 ENSDART00000101038
ENSDART00000129354
tmie
transmembrane inner ear
chr18_+_15876385 1.99 ENSDART00000142527
eea1
early endosome antigen 1
chr10_+_2587234 1.99 ENSDART00000126937
wu:fb59d01
wu:fb59d01
chr18_+_2189211 1.96 ENSDART00000170827
ccpg1
cell cycle progression 1
chr23_-_30431333 1.92 ENSDART00000146633
camta1a
calmodulin binding transcription activator 1a
chr20_+_25879826 1.89 ENSDART00000018519
zgc:153896
zgc:153896
chr7_-_45076131 1.87 ENSDART00000110590
zgc:194678
zgc:194678
chr19_+_1370504 1.84 ENSDART00000158946
dgat1a
diacylglycerol O-acyltransferase 1a
chr24_-_30091937 1.81 ENSDART00000148249
plppr4b
phospholipid phosphatase related 4b
chr16_-_49505275 1.79 ENSDART00000160784
satb1b
SATB homeobox 1b
chr3_+_19299309 1.79 ENSDART00000046297
ENSDART00000146955
ldlra
low density lipoprotein receptor a
chr1_-_14332283 1.70 ENSDART00000090025
wfs1a
Wolfram syndrome 1a (wolframin)
chr25_-_20258508 1.70 ENSDART00000133860
ENSDART00000006840
ENSDART00000173434
dnm1l
dynamin 1-like
chr1_+_44173245 1.67 ENSDART00000159450
ENSDART00000106048
ENSDART00000157763
ctnnd1
catenin (cadherin-associated protein), delta 1
chr23_+_11669337 1.66 ENSDART00000131355
cntn3a.1
contactin 3a, tandem duplicate 1
chr10_-_24371312 1.66 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr19_+_42469058 1.61 ENSDART00000076915
si:dkey-166k12.1
si:dkey-166k12.1
chr2_+_5927255 1.60 ENSDART00000152866
si:ch211-168b3.2
si:ch211-168b3.2
chr25_-_31739309 1.60 ENSDART00000098896
acot19
acyl-CoA thioesterase 19
chr6_-_60147517 1.52 ENSDART00000083453
slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr13_-_36034582 1.51 ENSDART00000133565
si:dkey-157l19.2
si:dkey-157l19.2
chr2_+_36862473 1.50 ENSDART00000135624
si:dkey-193b15.8
si:dkey-193b15.8
chr19_+_7810028 1.48 ENSDART00000081592
ENSDART00000140719
aqp10b
aquaporin 10b
chr18_+_38908903 1.45 ENSDART00000159834
myo5aa
myosin VAa
chr22_+_18786797 1.42 ENSDART00000141864
cbarpb
calcium channel, voltage-dependent, beta subunit associated regulatory protein b
chr23_-_12014931 1.40 ENSDART00000134652
si:dkey-178k16.1
si:dkey-178k16.1
chr25_+_336503 1.40 ENSDART00000160395
CU929262.1

chr5_-_42272517 1.39 ENSDART00000137692
ENSDART00000164363
si:ch211-207c6.2
si:ch211-207c6.2
chr1_+_44826593 1.37 ENSDART00000162200
STX3
zgc:165520
chr24_+_30392834 1.37 ENSDART00000162555
dpyda.1
dihydropyrimidine dehydrogenase a, tandem duplicate 1
chr25_-_13614702 1.37 ENSDART00000165510
ENSDART00000190959
fa2h
fatty acid 2-hydroxylase
chr24_+_7495945 1.37 ENSDART00000133525
ENSDART00000182460
ENSDART00000162954
kmt2ca
lysine (K)-specific methyltransferase 2Ca
chr8_+_40477264 1.36 ENSDART00000085559
gck
glucokinase (hexokinase 4)
chr10_-_44788554 1.36 ENSDART00000166965
tacr1b
tachykinin receptor 1b
chr23_+_11669109 1.36 ENSDART00000091416
cntn3a.1
contactin 3a, tandem duplicate 1
chr24_+_7782313 1.35 ENSDART00000111090
ptprh
protein tyrosine phosphatase, receptor type, h
chr18_-_15559817 1.35 ENSDART00000061681
si:ch211-245j22.3
si:ch211-245j22.3
chr3_+_15271943 1.32 ENSDART00000141752
asphd1
aspartate beta-hydroxylase domain containing 1
chr24_-_11908115 1.31 ENSDART00000184329
tm9sf1
transmembrane 9 superfamily member 1
chr3_-_3366590 1.31 ENSDART00000109428
ENSDART00000175329
si:dkey-46g23.1
si:dkey-46g23.1
chr9_-_23990416 1.30 ENSDART00000113176
col6a3
collagen, type VI, alpha 3
chr3_+_49097775 1.27 ENSDART00000169185
zgc:123284
zgc:123284
chr22_+_2207502 1.26 ENSDART00000169162
si:dkeyp-79b7.12
si:dkeyp-79b7.12
chr22_+_8979955 1.26 ENSDART00000144005
si:ch211-213a13.1
si:ch211-213a13.1
chr25_-_19433244 1.25 ENSDART00000154778
map1ab
microtubule-associated protein 1Ab
chr21_-_3770636 1.25 ENSDART00000053596
scamp1
secretory carrier membrane protein 1
chr9_+_54290896 1.25 ENSDART00000149175
pou4f3
POU class 4 homeobox 3
chr1_-_9249943 1.24 ENSDART00000055011
zgc:136472
zgc:136472
chr13_-_22843562 1.24 ENSDART00000142738
pbld
phenazine biosynthesis like protein domain containing
chr3_+_29714775 1.22 ENSDART00000041388
cacng2a
calcium channel, voltage-dependent, gamma subunit 2a
chr21_-_14966718 1.19 ENSDART00000151200
mmp17a
matrix metallopeptidase 17a
chr3_+_19609638 1.17 ENSDART00000079319
rprml
reprimo-like
chr22_-_34551568 1.17 ENSDART00000148147
rnf123
ring finger protein 123
chr15_+_43166511 1.12 ENSDART00000011737
flj13639
flj13639
chr5_+_45140914 1.11 ENSDART00000172702
smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr12_+_43585527 1.11 ENSDART00000161590
clrn3
clarin 3
chr1_-_9228007 1.09 ENSDART00000147277
ENSDART00000135219
gng13a
guanine nucleotide binding protein (G protein), gamma 13a
chr9_+_51265283 1.09 ENSDART00000137426
gcgb
glucagon b
chr25_-_34973211 1.08 ENSDART00000045177
cdk10
cyclin-dependent kinase 10
chr16_-_52821023 1.07 ENSDART00000074718
spire1b
spire-type actin nucleation factor 1b
chr18_+_14342326 1.02 ENSDART00000181013
ENSDART00000138372
si:dkey-246g23.2
si:dkey-246g23.2
chr4_+_7391110 1.01 ENSDART00000160708
ENSDART00000187823
tnni4a
troponin I4a
chr2_-_43196595 1.00 ENSDART00000141087
crema
cAMP responsive element modulator a
chr2_+_16597011 0.99 ENSDART00000160641
ENSDART00000125413
xrn1
5'-3' exoribonuclease 1
chr3_-_19495814 0.99 ENSDART00000162248
CU571315.3

chr13_-_25719628 0.99 ENSDART00000135383
si:dkey-192p21.6
si:dkey-192p21.6
chr21_+_27278120 0.97 ENSDART00000193882
si:dkey-175m17.7
si:dkey-175m17.7
chr21_-_30648106 0.97 ENSDART00000160800
ENSDART00000177022
phka1b
phosphorylase kinase, alpha 1b (muscle)
chr14_+_45028062 0.96 ENSDART00000184717
ENSDART00000185481
ATP8A1
ATPase phospholipid transporting 8A1
chr11_+_36231248 0.95 ENSDART00000131104
GPR62 (1 of many)
si:ch211-213o11.11
chr14_+_36497250 0.95 ENSDART00000184727
TENM3
si:dkey-237h12.3
chr20_-_7128612 0.93 ENSDART00000146755
ENSDART00000036871
si:ch211-121a2.4
si:ch211-121a2.4
chr18_-_39188664 0.92 ENSDART00000162983
mapk6
mitogen-activated protein kinase 6
chr14_+_15597049 0.92 ENSDART00000159732
si:dkey-203a12.8
si:dkey-203a12.8
chr24_+_25259154 0.91 ENSDART00000171125
gabrr3b
gamma-aminobutyric acid (GABA) A receptor, rho 3b
chr9_-_34986827 0.90 ENSDART00000137862
si:ch211-160b11.4
si:ch211-160b11.4
chr20_-_25709247 0.90 ENSDART00000146711
si:dkeyp-117h8.2
si:dkeyp-117h8.2
chr17_+_13031497 0.90 ENSDART00000115208
fbxo33
F-box protein 33
chr19_-_617246 0.88 ENSDART00000062551
cyp51
cytochrome P450, family 51
chr11_-_36009924 0.86 ENSDART00000189959
ENSDART00000167472
ENSDART00000191211
ENSDART00000191662
ENSDART00000191780
ENSDART00000192622
ENSDART00000179911
itpr1b
inositol 1,4,5-trisphosphate receptor, type 1b
chr3_+_24458899 0.85 ENSDART00000156655
cbx6b
chromobox homolog 6b
chr24_+_25258904 0.84 ENSDART00000155714
gabrr3b
gamma-aminobutyric acid (GABA) A receptor, rho 3b
chr6_-_33685325 0.84 ENSDART00000181883
mast2
microtubule associated serine/threonine kinase 2
chr2_-_30734098 0.82 ENSDART00000133769
rp1
retinitis pigmentosa 1 (autosomal dominant)
chr19_-_43750108 0.81 ENSDART00000171806
ppt1
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
chr4_+_19534833 0.81 ENSDART00000140028
lrrc4.1
leucine rich repeat containing 4.1
chr13_-_18174864 0.79 ENSDART00000079884
alox5a
arachidonate 5-lipoxygenase a
chr19_-_32600823 0.79 ENSDART00000134149
ENSDART00000187858
zgc:91944
zgc:91944
chr6_-_31348999 0.79 ENSDART00000153734
dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr17_+_23554932 0.78 ENSDART00000135814
pank1a
pantothenate kinase 1a
chr8_+_7740004 0.78 ENSDART00000170184
ENSDART00000187811
fgd1
FYVE, RhoGEF and PH domain containing 1
chr25_-_13614863 0.78 ENSDART00000121859
fa2h
fatty acid 2-hydroxylase
chr2_-_32738535 0.76 ENSDART00000135293
nrbp2a
nuclear receptor binding protein 2a
chr5_-_62940851 0.76 ENSDART00000137052
specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr1_+_44711446 0.75 ENSDART00000193481
ENSDART00000003895
ssrp1b
structure specific recognition protein 1b
chr5_+_25317061 0.74 ENSDART00000170097
trpm6
transient receptor potential cation channel, subfamily M, member 6
chr10_-_10969596 0.74 ENSDART00000092011
exd3
exonuclease 3'-5' domain containing 3
chr15_+_21276735 0.73 ENSDART00000111213
ubash3bb
ubiquitin associated and SH3 domain containing Bb
chr23_+_22785375 0.71 ENSDART00000142085
rerea
arginine-glutamic acid dipeptide (RE) repeats a
chr14_-_8271686 0.70 ENSDART00000165120
purab
purine-rich element binding protein Ab
chr4_+_20954929 0.70 ENSDART00000143674
nav3
neuron navigator 3
chr16_+_11188810 0.70 ENSDART00000186011
cicb
capicua transcriptional repressor b
chr17_-_50355512 0.69 ENSDART00000041685
otofb
otoferlin b
chr11_-_15090564 0.65 ENSDART00000162079
slc1a8a
solute carrier family 1 (glutamate transporter), member 8a
chr11_-_40257225 0.64 ENSDART00000139009
TRIM62 (1 of many)
si:ch211-193i15.2
chr4_+_14899720 0.64 ENSDART00000187456
akr1b1
aldo-keto reductase family 1, member B1 (aldose reductase)
chr14_-_4120636 0.64 ENSDART00000059230
irf2
interferon regulatory factor 2
chr5_-_57289872 0.63 ENSDART00000189893
ENSDART00000050957
fer
fer (fps/fes related) tyrosine kinase
chr16_+_20934353 0.62 ENSDART00000052660
skap2
src kinase associated phosphoprotein 2
chr4_+_10888762 0.61 ENSDART00000136049
syt10
synaptotagmin X
chr15_+_29024895 0.61 ENSDART00000141164
ENSDART00000144126
si:ch211-137a8.2
si:ch211-137a8.2
chr22_+_1421212 0.60 ENSDART00000161813
zgc:101130
zgc:101130
chr9_+_30275139 0.60 ENSDART00000131781
rpgra
retinitis pigmentosa GTPase regulator a
chr20_-_49889111 0.60 ENSDART00000058858
kif13bb
kinesin family member 13Bb
chr17_-_29311835 0.59 ENSDART00000104224
tecpr2
tectonin beta-propeller repeat containing 2
chr25_+_33063762 0.59 ENSDART00000189974
tln2b
talin 2b
chr14_+_3071110 0.59 ENSDART00000162445
hmgxb3
HMG box domain containing 3
chr2_+_52847049 0.58 ENSDART00000121980
creb3l3b
cAMP responsive element binding protein 3-like 3b
chr22_-_9736050 0.57 ENSDART00000152919
si:dkey-286j17.4
si:dkey-286j17.4
chr22_-_13165186 0.57 ENSDART00000105762
ahr2
aryl hydrocarbon receptor 2
chr15_-_563877 0.55 ENSDART00000128032
cbln18
cerebellin 18
chr5_+_11290851 0.54 ENSDART00000180408
CABZ01077124.1

chr3_-_19200571 0.54 ENSDART00000131503
ENSDART00000012335
rfx1a
regulatory factor X, 1a (influences HLA class II expression)
chr11_+_37049347 0.53 ENSDART00000109235
bicd2
bicaudal D homolog 2 (Drosophila)
chr9_-_41784799 0.52 ENSDART00000144573
ENSDART00000112542
ENSDART00000190486
obsl1b
obscurin-like 1b
chr13_-_37619159 0.52 ENSDART00000186348
zgc:152791
zgc:152791
chr16_+_54829293 0.52 ENSDART00000024729
pabpc1a
poly(A) binding protein, cytoplasmic 1a
chr21_+_2102829 0.51 ENSDART00000157922
AL627305.1

chr3_-_24456451 0.50 ENSDART00000024480
ENSDART00000156814
baiap2l2a
BAI1-associated protein 2-like 2a
chr1_+_2321384 0.50 ENSDART00000157662
farp1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr17_-_23727978 0.50 ENSDART00000079600
minpp1a
multiple inositol-polyphosphate phosphatase 1a
chr20_+_41906960 0.49 ENSDART00000193460
cep85l
centrosomal protein 85, like
chr25_-_32449235 0.49 ENSDART00000115343
atp8b4
ATPase phospholipid transporting 8B4
chr13_-_25745089 0.47 ENSDART00000189333
ENSDART00000147420
sgpl1
sphingosine-1-phosphate lyase 1
chr12_-_18872717 0.46 ENSDART00000126300
shisa8b
shisa family member 8b
chr20_-_34028967 0.46 ENSDART00000153408
ENSDART00000033817
scyl3
SCY1-like, kinase-like 3
chr7_-_52334840 0.46 ENSDART00000174173
CR938716.1

chr4_-_22338906 0.46 ENSDART00000131402
golgb1
golgin B1
chr15_+_29276508 0.44 ENSDART00000170537
ENSDART00000126559
rap1gap2a
RAP1 GTPase activating protein 2a
chr22_-_32360464 0.44 ENSDART00000148886
pcbp4
poly(rC) binding protein 4
chr23_+_34047413 0.44 ENSDART00000143933
ENSDART00000123925
ENSDART00000176139
chchd6a
coiled-coil-helix-coiled-coil-helix domain containing 6a
chr7_-_7692992 0.43 ENSDART00000192619
aadat
aminoadipate aminotransferase
chr10_-_42882215 0.43 ENSDART00000180580
ENSDART00000187374
FP236542.1

chr5_+_42400777 0.43 ENSDART00000183114
BX548073.8

chr7_+_18075504 0.42 ENSDART00000173689
si:ch73-40a2.1
si:ch73-40a2.1
chr2_-_44038698 0.42 ENSDART00000079582
ENSDART00000146804
kirrel1b
kirre like nephrin family adhesion molecule 1b
chr7_+_13639473 0.38 ENSDART00000157870
ENSDART00000032899
clpxa
caseinolytic mitochondrial matrix peptidase chaperone subunit a
chr20_+_52546186 0.37 ENSDART00000110777
ENSDART00000153377
ENSDART00000153013
ENSDART00000042704
eef1db
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr21_-_22827548 0.37 ENSDART00000079161
angptl5
angiopoietin-like 5
chr7_+_24522308 0.36 ENSDART00000173542
btr09
bloodthirsty-related gene family, member 9
chr15_+_44093286 0.36 ENSDART00000114352
zgc:112998
zgc:112998
chr8_-_38159805 0.36 ENSDART00000112331
ENSDART00000180006
adgra2
adhesion G protein-coupled receptor A2
chr3_-_29910547 0.36 ENSDART00000151501
RUNDC1
si:dkey-151m15.5
chr24_+_1042594 0.35 ENSDART00000109117
si:dkey-192l18.9
si:dkey-192l18.9
chr11_-_6265574 0.35 ENSDART00000181974
ENSDART00000104405
ccl25b
chemokine (C-C motif) ligand 25b
chr7_+_66822229 0.34 ENSDART00000112109
lyve1a
lymphatic vessel endothelial hyaluronic receptor 1a
chr4_-_16334362 0.34 ENSDART00000101461
epyc
epiphycan
chr12_-_18872927 0.34 ENSDART00000187717
shisa8b
shisa family member 8b
chr10_-_36618674 0.33 ENSDART00000135302
rsf1b.1
remodeling and spacing factor 1b, tandem duplicate 1
chr10_+_20628698 0.33 ENSDART00000064666
prnpb
prion protein b
chr7_-_8022741 0.33 ENSDART00000172841
si:ch211-163c2.1
si:ch211-163c2.1
chr22_+_2632961 0.33 ENSDART00000106278
znf1173
zinc finger protein 1173
chr9_+_13229585 0.31 ENSDART00000154879
ENSDART00000141705
carf
calcium responsive transcription factor
chr8_+_30709685 0.30 ENSDART00000133989
upb1
ureidopropionase, beta
chr20_+_43379029 0.29 ENSDART00000142486
ENSDART00000186486
unc93a
unc-93 homolog A
chr11_-_15090118 0.28 ENSDART00000171118
slc1a8a
solute carrier family 1 (glutamate transporter), member 8a
chr8_+_23521974 0.28 ENSDART00000188130
ENSDART00000129378
sema3gb
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr8_-_43834442 0.27 ENSDART00000191927
adgrd1
adhesion G protein-coupled receptor D1
chr8_-_38317914 0.26 ENSDART00000125920
pdlim2
PDZ and LIM domain 2 (mystique)
chr10_-_10969444 0.25 ENSDART00000138041
exd3
exonuclease 3'-5' domain containing 3
chr17_-_2690083 0.25 ENSDART00000135374
ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr3_+_13482542 0.24 ENSDART00000161287
CABZ01079251.1

chr8_+_28467893 0.24 ENSDART00000189724
slc52a3
solute carrier family 52 (riboflavin transporter), member 3
chr16_+_21242491 0.23 ENSDART00000145886
osbpl3b
oxysterol binding protein-like 3b
chr17_+_52823015 0.23 ENSDART00000160507
ENSDART00000186979
meis2a
Meis homeobox 2a

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxd11a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.5 GO:0046677 response to antibiotic(GO:0046677)
1.0 3.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.8 2.5 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.7 6.5 GO:0006833 water transport(GO:0006833)
0.5 1.4 GO:0071312 response to cocaine(GO:0042220) cellular response to alkaloid(GO:0071312) cellular response to cocaine(GO:0071314)
0.4 2.6 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.3 1.7 GO:1903146 regulation of mitophagy(GO:1903146)
0.3 1.8 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.3 2.0 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.3 1.4 GO:0006212 uracil catabolic process(GO:0006212) uracil metabolic process(GO:0019860)
0.2 1.4 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.2 1.0 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.2 1.5 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 1.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.2 1.1 GO:0016572 histone phosphorylation(GO:0016572)
0.2 0.8 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.2 0.6 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.2 0.8 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.2 1.1 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.2 0.3 GO:0019483 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.1 4.0 GO:0009636 response to toxic substance(GO:0009636)
0.1 1.4 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 0.4 GO:0022009 central nervous system vasculogenesis(GO:0022009)
0.1 0.4 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.1 2.0 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.3 GO:0061400 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion(GO:0061400)
0.1 2.4 GO:0006828 manganese ion transport(GO:0006828)
0.1 1.1 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.7 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.1 0.4 GO:0048025 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 1.3 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 2.2 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 1.2 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.1 0.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.8 GO:0019372 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 1.0 GO:0016075 rRNA catabolic process(GO:0016075)
0.1 1.2 GO:0014823 response to activity(GO:0014823)
0.1 0.6 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.8 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.2 GO:0035994 response to muscle stretch(GO:0035994)
0.1 0.5 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.1 0.7 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 2.3 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 0.8 GO:0060325 face morphogenesis(GO:0060325)
0.1 3.2 GO:0015914 phospholipid transport(GO:0015914)
0.1 0.7 GO:0072576 liver morphogenesis(GO:0072576)
0.0 1.7 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.2 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 1.1 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 1.3 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 2.6 GO:0006096 glycolytic process(GO:0006096)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 1.2 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.9 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.1 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.0 0.4 GO:0042407 cristae formation(GO:0042407)
0.0 1.4 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.8 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.9 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 2.1 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 1.0 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.9 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 1.8 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.4 GO:0039022 pronephric duct development(GO:0039022)
0.0 1.8 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 1.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.7 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 2.1 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 2.3 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 1.2 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.1 GO:0006531 aspartate metabolic process(GO:0006531)
0.0 2.9 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.0 1.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.5 GO:0003094 glomerular filtration(GO:0003094)
0.0 1.0 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.7 GO:0051262 protein tetramerization(GO:0051262)
0.0 0.8 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.6 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 1.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.5 GO:0030149 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.0 0.6 GO:0042113 B cell activation(GO:0042113)
0.0 2.3 GO:0042391 regulation of membrane potential(GO:0042391)
0.0 0.2 GO:0045661 regulation of myoblast differentiation(GO:0045661)
0.0 1.0 GO:0042594 response to starvation(GO:0042594)
0.0 0.2 GO:1902017 regulation of cilium assembly(GO:1902017)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0097225 sperm midpiece(GO:0097225)
0.1 2.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.3 GO:0031213 RSF complex(GO:0031213)
0.1 1.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.4 GO:1990909 Wnt signalosome(GO:1990909)
0.1 1.0 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.0 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 0.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 1.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 1.7 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 2.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.9 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.1 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.0 GO:0005861 troponin complex(GO:0005861)
0.0 1.4 GO:0030141 secretory granule(GO:0030141)
0.0 0.1 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 1.0 GO:0031941 filamentous actin(GO:0031941)
0.0 0.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 2.3 GO:0034703 cation channel complex(GO:0034703)
0.0 1.3 GO:0043025 neuronal cell body(GO:0043025)
0.0 1.3 GO:0016459 myosin complex(GO:0016459)
0.0 0.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 2.2 GO:0030424 axon(GO:0030424)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.5 GO:0008131 primary amine oxidase activity(GO:0008131)
1.1 3.4 GO:0015562 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
1.0 3.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.7 2.1 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
0.6 5.2 GO:0015250 water channel activity(GO:0015250)
0.5 1.4 GO:0016496 substance P receptor activity(GO:0016496)
0.4 1.8 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.4 2.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.3 1.7 GO:0005372 water transmembrane transporter activity(GO:0005372)
0.3 1.4 GO:0002058 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.2 1.0 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.2 1.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 1.4 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 1.1 GO:0031769 glucagon receptor binding(GO:0031769)
0.2 0.8 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.2 1.8 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.8 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.5 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.1 3.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.5 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.1 1.5 GO:0015295 solute:proton symporter activity(GO:0015295)
0.1 2.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 2.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 2.9 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.1 2.1 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.5 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.8 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 0.9 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.8 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 1.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.6 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 0.5 GO:0034452 dynactin binding(GO:0034452)
0.1 2.2 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 1.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.2 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 1.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.0 1.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.9 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 1.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.5 GO:0042805 actinin binding(GO:0042805)
0.0 1.1 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.8 GO:0044325 ion channel binding(GO:0044325)
0.0 1.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 1.7 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 1.0 GO:0030276 clathrin binding(GO:0030276)
0.0 1.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 3.8 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 2.1 GO:0020037 heme binding(GO:0020037)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.3 2.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 0.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 1.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.7 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 2.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 2.0 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production