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PRJEB1986: zebrafish developmental stages transcriptome

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Results for hoxd12a

Z-value: 0.64

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Transcription factors associated with hoxd12a

Gene Symbol Gene ID Gene Info
hoxd12a
ENSDARG00000059263 homeobox D12a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxd12adr11_v1_chr9_-_1986014_19860140.789.4e-05Click!

Activity profile of hoxd12a motif

Sorted Z-values of hoxd12a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_6065416 1.83 ENSDART00000037698
uck2b
uridine-cytidine kinase 2b
chr21_-_22357985 1.37 ENSDART00000101751
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr21_+_20715020 1.34 ENSDART00000015224
gadd45gb.1
growth arrest and DNA-damage-inducible, gamma b, tandem duplicate 1
chr11_+_2198831 1.29 ENSDART00000160515
hoxc6b
homeobox C6b
chr8_+_8937723 1.29 ENSDART00000145970
si:dkey-83k24.5
si:dkey-83k24.5
chr19_-_31007417 1.26 ENSDART00000048144
rbbp4
retinoblastoma binding protein 4
chr17_-_31695217 1.23 ENSDART00000104332
ENSDART00000143090
lin52
lin-52 DREAM MuvB core complex component
chr25_+_18964782 1.18 ENSDART00000017299
tdg.1
thymine DNA glycosylase, tandem duplicate 1
chr19_+_7424347 1.15 ENSDART00000004622
sf3b4
splicing factor 3b, subunit 4
chr17_+_17764979 1.15 ENSDART00000105013
alkbh1
alkB homolog 1, histone H2A dioxygenase
chr16_+_20910186 1.08 ENSDART00000046766
hoxa10b
homeobox A10b
chr2_-_34138064 1.00 ENSDART00000133381
cenpl
centromere protein L
chr13_+_35472803 0.99 ENSDART00000011583
mkks
McKusick-Kaufman syndrome
chr25_-_21066136 0.98 ENSDART00000109520
fbxl14a
F-box and leucine-rich repeat protein 14a
chr19_-_1948236 0.97 ENSDART00000163344
znrf2a
zinc and ring finger 2a
chr15_+_29116063 0.96 ENSDART00000016112
ENSDART00000153609
ENSDART00000155630
capns1b
calpain, small subunit 1 b
chr14_+_16287968 0.95 ENSDART00000106593
prpf19
pre-mRNA processing factor 19
chr7_-_24994568 0.95 ENSDART00000002961
rcor2
REST corepressor 2
chr5_+_32490595 0.92 ENSDART00000165417
ndor1
NADPH dependent diflavin oxidoreductase 1
chr2_+_371759 0.90 ENSDART00000153788
si:dkey-33c14.7
si:dkey-33c14.7
chr18_-_17087138 0.90 ENSDART00000135597
zc3h18
zinc finger CCCH-type containing 18
chr23_+_36087219 0.89 ENSDART00000154825
hoxc3a
homeobox C3a
chr8_-_12432604 0.87 ENSDART00000133350
ENSDART00000140699
ENSDART00000101174
traf1
TNF receptor-associated factor 1
chr9_-_42730672 0.85 ENSDART00000136728
fkbp7
FK506 binding protein 7
chr14_+_989733 0.84 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
si:ch73-308l14.2
chr22_-_17611742 0.84 ENSDART00000144031
gpx4a
glutathione peroxidase 4a
chr3_+_11072958 0.84 ENSDART00000158899
mrps7
mitochondrial ribosomal protein S7
chr1_-_38171648 0.84 ENSDART00000137451
ENSDART00000047159
hmgb2a
high mobility group box 2a
chr16_+_33655890 0.83 ENSDART00000143757
fhl3a
four and a half LIM domains 3a
chr5_-_69499486 0.83 ENSDART00000023983
ENSDART00000180293
psat1
phosphoserine aminotransferase 1
chr7_+_49681040 0.79 ENSDART00000176372
ENSDART00000192172
rassf7b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr21_-_3007412 0.78 ENSDART00000190839
CKS2
zgc:86839
chr15_+_2857556 0.78 ENSDART00000157758
mre11a
MRE11 homolog A, double strand break repair nuclease
chr9_+_41080029 0.77 ENSDART00000141179
ENSDART00000019289
zgc:136439
zgc:136439
chr5_-_24542726 0.77 ENSDART00000182975
trmt2a
tRNA methyltransferase 2 homolog A
chr21_+_13128180 0.77 ENSDART00000081426
odf2a
outer dense fiber of sperm tails 2a
chr16_-_33650578 0.76 ENSDART00000058460
utp11l
UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)
chr6_-_13376060 0.76 ENSDART00000104732
ENSDART00000125271
arl6ip6
ADP-ribosylation factor-like 6 interacting protein 6
chr5_-_31856681 0.76 ENSDART00000187817
pkn3
protein kinase N3
chr22_+_10440991 0.75 ENSDART00000064805
cenpp
centromere protein P
chr23_-_16734009 0.74 ENSDART00000125449
si:ch211-224l10.4
si:ch211-224l10.4
chr7_-_26125092 0.74 ENSDART00000079364
snapc2
small nuclear RNA activating complex, polypeptide 2
chr11_-_6880725 0.73 ENSDART00000007204
ddx49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr7_+_7570701 0.72 ENSDART00000172774
si:ch211-42c5.5
si:ch211-42c5.5
chr24_+_21540842 0.71 ENSDART00000091529
wasf3b
WAS protein family, member 3b
chr12_-_17199381 0.71 ENSDART00000193292
lipf
lipase, gastric
chr2_+_31330358 0.70 ENSDART00000178066
clul1
clusterin-like 1 (retinal)
chr11_-_16115804 0.70 ENSDART00000143436
ENSDART00000157928
rpf1
ribosome production factor 1 homolog
chr11_+_2202987 0.69 ENSDART00000190008
ENSDART00000173139
hoxc6b
homeobox C6b
chr7_+_29167744 0.69 ENSDART00000076345
slc38a8b
solute carrier family 38, member 8b
chr14_+_30568961 0.68 ENSDART00000184303
mrpl11
mitochondrial ribosomal protein L11
chr4_-_64336270 0.68 ENSDART00000131672
znf1147
zinc finger protein 1147
chr6_-_7711349 0.68 ENSDART00000032494
ttc26
tetratricopeptide repeat domain 26
chr22_-_10440688 0.68 ENSDART00000111962
nol8
nucleolar protein 8
chr9_-_2892250 0.68 ENSDART00000140695
cdca7a
cell division cycle associated 7a
chr3_-_27065477 0.67 ENSDART00000185660
atf7ip2
activating transcription factor 7 interacting protein 2
chr9_-_2892045 0.66 ENSDART00000137201
cdca7a
cell division cycle associated 7a
chr6_-_34838397 0.65 ENSDART00000060169
ENSDART00000169605
mier1a
mesoderm induction early response 1a, transcriptional regulator
chr11_-_37717709 0.64 ENSDART00000177280
yod1
YOD1 deubiquitinase
chr16_-_12060488 0.64 ENSDART00000188733
si:ch211-69g19.2
si:ch211-69g19.2
chr7_+_55292959 0.64 ENSDART00000147539
ENSDART00000073555
ctu2
cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr12_+_27117609 0.64 ENSDART00000076154
hoxb8b
homeobox B8b
chr16_+_42471455 0.63 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr5_-_32396929 0.63 ENSDART00000023977
fbxw2
F-box and WD repeat domain containing 2
chr25_+_30105628 0.62 ENSDART00000187704
si:ch211-147k10.5
si:ch211-147k10.5
chr19_-_25081711 0.62 ENSDART00000058513
xkr8.3
XK, Kell blood group complex subunit-related family, member 8, tandem duplicate 3
chr2_+_4402765 0.61 ENSDART00000159525
bambib
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b
chr18_-_3571583 0.61 ENSDART00000168842
eif2a
eukaryotic translation initiation factor 2A
chr19_+_29808699 0.60 ENSDART00000051799
ENSDART00000164205
hdac1
histone deacetylase 1
chr7_-_55051692 0.60 ENSDART00000170637
tpcn2
two pore segment channel 2
chr4_-_20108833 0.59 ENSDART00000100867
fam3c
family with sequence similarity 3, member C
chr16_-_10316359 0.59 ENSDART00000104025
flot1b
flotillin 1b
chr7_+_24205034 0.59 ENSDART00000018580
nedd8
neural precursor cell expressed, developmentally down-regulated 8
chr25_+_3294150 0.58 ENSDART00000030683
tmpob
thymopoietin b
chr4_-_25271455 0.58 ENSDART00000066936
tmem110l
transmembrane protein 110, like
chr3_-_40254634 0.58 ENSDART00000154562
top3a
DNA topoisomerase III alpha
chr4_-_18851365 0.58 ENSDART00000021782
mcat
malonyl CoA:ACP acyltransferase (mitochondrial)
chr13_+_29925397 0.57 ENSDART00000123482
cuedc2
CUE domain containing 2
chr2_-_22966076 0.57 ENSDART00000143412
ENSDART00000146014
ENSDART00000183443
ENSDART00000191056
ENSDART00000183539
sap130b
Sin3A-associated protein b
chr21_-_43131752 0.56 ENSDART00000024137
p4ha2
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2
chr15_+_834697 0.56 ENSDART00000154861
ENSDART00000160694
si:dkey-7i4.14
zgc:174573
si:dkey-7i4.14
zgc:174573
chr6_-_14038804 0.56 ENSDART00000184606
ENSDART00000184609
etv5b
ets variant 5b
chr9_+_500052 0.56 ENSDART00000166707
CU984600.1

chr22_+_20169352 0.56 ENSDART00000169055
ENSDART00000061617
hmg20b
high mobility group 20B
chr23_+_39611688 0.55 ENSDART00000034690
otud3
OTU deubiquitinase 3
chr14_-_25985698 0.54 ENSDART00000172909
ENSDART00000123053
atox1
antioxidant 1 copper chaperone
chr25_+_7241084 0.54 ENSDART00000190501
ENSDART00000190588
hmg20a
high mobility group 20A
chr4_+_40955267 0.54 ENSDART00000137775
znf1136
zinc finger protein 1136
chr14_+_33507608 0.53 ENSDART00000038128
mcts1
malignant T cell amplified sequence 1
chr16_-_47426482 0.53 ENSDART00000148631
ENSDART00000149723
sept7b
septin 7b
chr15_+_8767650 0.53 ENSDART00000033871
ap2s1
adaptor-related protein complex 2, sigma 1 subunit
chr6_-_53334259 0.52 ENSDART00000172465
gnb1b
guanine nucleotide binding protein (G protein), beta polypeptide 1b
chr24_-_36175365 0.52 ENSDART00000065338
pak1ip1
PAK1 interacting protein 1
chr8_-_16788626 0.52 ENSDART00000191652
CR759968.2

chr22_-_9860792 0.52 ENSDART00000155908
si:dkey-253d23.2
si:dkey-253d23.2
chr6_-_49215790 0.51 ENSDART00000103376
ENSDART00000132347
ENSDART00000132131
ENSDART00000143252
ENSDART00000065033
ngfb
nerve growth factor b (beta polypeptide)
chr9_-_29039506 0.51 ENSDART00000100744
tmem177
transmembrane protein 177
chr17_+_38295847 0.51 ENSDART00000008532
mbip
MAP3K12 binding inhibitory protein 1
chr7_-_37622370 0.50 ENSDART00000173523
nkd1
naked cuticle homolog 1 (Drosophila)
chr5_+_38744660 0.50 ENSDART00000180506
si:dkey-58f10.6
si:dkey-58f10.6
chr12_-_29233738 0.50 ENSDART00000153175
si:ch211-214e3.5
si:ch211-214e3.5
chr16_+_33144306 0.50 ENSDART00000101953
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr16_+_32014552 0.49 ENSDART00000047570
mboat7
membrane bound O-acyltransferase domain containing 7
chr7_-_25133783 0.48 ENSDART00000173781
ENSDART00000121943
ENSDART00000077219
badb
BCL2 associated agonist of cell death b
chr14_-_10387377 0.48 ENSDART00000145118
commd5
COMM domain containing 5
chr24_+_21174523 0.47 ENSDART00000183849
naa50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr4_-_69127091 0.47 ENSDART00000136092
si:ch211-209j12.3
si:ch211-209j12.3
chr5_+_32490238 0.47 ENSDART00000191839
ndor1
NADPH dependent diflavin oxidoreductase 1
chr22_+_10646928 0.47 ENSDART00000038465
rassf1
Ras association (RalGDS/AF-6) domain family 1
chr19_+_29808471 0.47 ENSDART00000186428
hdac1
histone deacetylase 1
chr7_-_24994722 0.46 ENSDART00000131671
rcor2
REST corepressor 2
chr20_-_19530751 0.46 ENSDART00000148574
eif2b4
eukaryotic translation initiation factor 2B, subunit 4 delta
chr11_+_2416064 0.46 ENSDART00000067117
ube2v1
ubiquitin-conjugating enzyme E2 variant 1
chr3_+_34140507 0.46 ENSDART00000131802
si:dkey-204f11.64
si:dkey-204f11.64
chr2_-_45510699 0.45 ENSDART00000024034
ENSDART00000145634
gpsm2
G protein signaling modulator 2
chr10_+_25947946 0.44 ENSDART00000064393
ufm1
ubiquitin-fold modifier 1
chr16_+_10429770 0.44 ENSDART00000173132
vars
valyl-tRNA synthetase
chr15_+_5132439 0.44 ENSDART00000010350
pgm2l1
phosphoglucomutase 2-like 1
chr6_+_49742164 0.44 ENSDART00000024578
npepl1
aminopeptidase like 1
chr23_+_33752275 0.43 ENSDART00000007260
si:ch211-210c8.6
si:ch211-210c8.6
chr10_-_31805923 0.42 ENSDART00000077785
vps26bl
vacuolar protein sorting 26 homolog B, like
chr18_+_41542542 0.42 ENSDART00000087445
tsen34
TSEN34 tRNA splicing endonuclease subunit
chr11_+_25560632 0.41 ENSDART00000033914
mbd1b
methyl-CpG binding domain protein 1b
chr3_+_36284986 0.41 ENSDART00000059533
wipi1
WD repeat domain, phosphoinositide interacting 1
chr5_+_29714786 0.41 ENSDART00000148314
ddx31
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr18_+_18000887 0.41 ENSDART00000147797
si:ch211-212o1.2
si:ch211-212o1.2
chr8_+_23861461 0.41 ENSDART00000037109
srpk1a
SRSF protein kinase 1a
chr24_-_31223232 0.40 ENSDART00000164155
alg14
ALG14, UDP-N-acetylglucosaminyltransferase subunit
chr22_+_17192767 0.40 ENSDART00000130810
ENSDART00000183006
atpaf1
ATP synthase mitochondrial F1 complex assembly factor 1
chr6_+_3730843 0.40 ENSDART00000019630
FO704755.1

chr24_+_21174851 0.39 ENSDART00000154940
ENSDART00000155977
ENSDART00000122762
naa50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr13_+_30228077 0.39 ENSDART00000100813
ENSDART00000147729
ENSDART00000133404
rps24
ribosomal protein S24
chr17_+_1632294 0.39 ENSDART00000191959
srp14
signal recognition particle 14
chr20_-_154989 0.39 ENSDART00000064542
rpf2
ribosome production factor 2 homolog
chr15_+_21744680 0.39 ENSDART00000016860
ppp2r1bb
protein phosphatase 2, regulatory subunit A, beta b
chr18_+_33725576 0.39 ENSDART00000146816
si:dkey-145c18.5
si:dkey-145c18.5
chr16_+_33144112 0.39 ENSDART00000183149
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr5_-_32489796 0.38 ENSDART00000168870
gpr107
G protein-coupled receptor 107
chr18_+_3140682 0.38 ENSDART00000166382
clns1a
chloride channel, nucleotide-sensitive, 1A
chr21_-_43665537 0.38 ENSDART00000157610
si:dkey-229d11.3
si:dkey-229d11.3
chr20_+_34845672 0.38 ENSDART00000128895
emilin1a
elastin microfibril interfacer 1a
chr5_+_27434601 0.37 ENSDART00000064701
loxl2b
lysyl oxidase-like 2b
chr19_+_30884960 0.37 ENSDART00000140603
ENSDART00000183224
ENSDART00000135484
ENSDART00000139599
yars
tyrosyl-tRNA synthetase
chr6_+_49551614 0.36 ENSDART00000022581
rab22a
RAB22A, member RAS oncogene family
chr6_-_2154137 0.36 ENSDART00000162656
tgm5l
transglutaminase 5, like
chr20_+_405811 0.35 ENSDART00000149311
gpr63
G protein-coupled receptor 63
chr3_+_25166805 0.35 ENSDART00000077493
TST
zgc:162544
chr7_-_18508815 0.35 ENSDART00000173539
rgs12a
regulator of G protein signaling 12a
chr19_+_42227400 0.34 ENSDART00000131574
ENSDART00000135436
jtb
jumping translocation breakpoint
chr11_+_24716837 0.34 ENSDART00000145217
zgc:153953
zgc:153953
chr14_-_42997145 0.33 ENSDART00000172801
pcdh10b
protocadherin 10b
chr10_-_17222083 0.33 ENSDART00000134059
depdc5
DEP domain containing 5
chr10_+_26612321 0.33 ENSDART00000134322
fhl1b
four and a half LIM domains 1b
chr24_-_24796583 0.33 ENSDART00000144791
ENSDART00000146570
pde7a
phosphodiesterase 7A
chr10_-_41397663 0.33 ENSDART00000158038
gpat4
glycerol-3-phosphate acyltransferase 4
chr15_-_28262632 0.32 ENSDART00000134601
ENSDART00000175022
prpf8
pre-mRNA processing factor 8
chr5_+_23599259 0.32 ENSDART00000138902
kat5b
K(lysine) acetyltransferase 5b
chr11_-_36051004 0.32 ENSDART00000025033
gpx1a
glutathione peroxidase 1a
chr7_+_20524064 0.32 ENSDART00000052917
slc3a2a
solute carrier family 3 (amino acid transporter heavy chain), member 2a
chr4_-_30712588 0.31 ENSDART00000142393
si:dkey-16p19.5
si:dkey-16p19.5
chr4_-_64336954 0.31 ENSDART00000157986
znf1147
zinc finger protein 1147
chr22_+_10676981 0.31 ENSDART00000138016
hyal2b
hyaluronoglucosaminidase 2b
chr13_+_21768447 0.31 ENSDART00000100941
chchd1
coiled-coil-helix-coiled-coil-helix domain containing 1
chr5_-_43935119 0.31 ENSDART00000142271
si:ch211-204c21.1
si:ch211-204c21.1
chr17_+_42274825 0.31 ENSDART00000020156
pax1a
paired box 1a
chr19_+_28291062 0.30 ENSDART00000163382
lpcat1
lysophosphatidylcholine acyltransferase 1
chr21_-_36396334 0.30 ENSDART00000183627
mrpl22
mitochondrial ribosomal protein L22
chr10_-_5857548 0.30 ENSDART00000166933
si:ch211-281k19.2
si:ch211-281k19.2
chr6_+_33885828 0.30 ENSDART00000179994
gpbp1l1
GC-rich promoter binding protein 1-like 1
chr4_+_39368978 0.30 ENSDART00000160640
si:dkey-261o4.1
si:dkey-261o4.1
chr6_-_57476465 0.30 ENSDART00000128065
ddx27
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chr16_-_9675982 0.29 ENSDART00000113724
mal2
mal, T cell differentiation protein 2 (gene/pseudogene)
chr2_-_37458527 0.29 ENSDART00000146820
si:dkey-57k2.7
si:dkey-57k2.7
chr20_-_20355577 0.29 ENSDART00000018500
hif1ab
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b
chr6_-_30485009 0.29 ENSDART00000025698
zgc:153311
zgc:153311
chr7_-_23873173 0.29 ENSDART00000101408
zgc:162171
zgc:162171
chr17_+_23255365 0.28 ENSDART00000180277
AL935174.5

chr25_-_3192405 0.28 ENSDART00000104835
hps5
Hermansky-Pudlak syndrome 5
chr20_-_23656516 0.28 ENSDART00000149735
cbr4
carbonyl reductase 4
chr5_+_23598364 0.28 ENSDART00000132155
kat5b
K(lysine) acetyltransferase 5b
chr7_+_30240791 0.27 ENSDART00000109243
sema4bb
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Bb
chr21_-_17296789 0.27 ENSDART00000192180
gfi1b
growth factor independent 1B transcription repressor
chr19_+_3840955 0.27 ENSDART00000172305
lsm10
LSM10, U7 small nuclear RNA associated
chr23_+_19691146 0.27 ENSDART00000143001
si:dkey-93l1.6
si:dkey-93l1.6
chr7_-_30624435 0.27 ENSDART00000173828
rnf111
ring finger protein 111
chr20_-_23657304 0.27 ENSDART00000016913
cbr4
carbonyl reductase 4
chr24_-_26632171 0.27 ENSDART00000008374
ENSDART00000017384
tnikb
TRAF2 and NCK interacting kinase b
chr19_+_30885258 0.27 ENSDART00000143394
yars
tyrosyl-tRNA synthetase
chr18_-_41161828 0.27 ENSDART00000114993
CABZ01005876.1

chr11_+_2554856 0.27 ENSDART00000173000
zgc:113184
zgc:113184
chr24_-_17029374 0.27 ENSDART00000039267
ptgdsb.1
prostaglandin D2 synthase b, tandem duplicate 1
chr22_-_15671525 0.26 ENSDART00000080286
si:ch1073-396h14.1
si:ch1073-396h14.1
chr19_-_33370271 0.26 ENSDART00000132628
nkd3l
naked cuticle homolog 3, like
chr17_+_30843881 0.25 ENSDART00000149600
ENSDART00000148547
tpp1
tripeptidyl peptidase I
chr19_+_7595924 0.25 ENSDART00000140083
s100s
S100 calcium binding protein S
chr22_-_9901788 0.25 ENSDART00000141526
znf991
zinc finger protein 991
chr3_-_50147160 0.24 ENSDART00000191341
btr02
bloodthirsty-related gene family, member 2
chr2_-_55797318 0.24 ENSDART00000158147
calr3b
calreticulin 3b
chr4_+_16768961 0.24 ENSDART00000143926
BX649500.1

chr19_+_19989380 0.24 ENSDART00000142841
osbpl3a
oxysterol binding protein-like 3a

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxd12a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.3 0.8 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 1.0 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.2 1.1 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.2 0.9 GO:0071962 establishment of mitotic sister chromatid cohesion(GO:0034087) mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.2 0.6 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.2 0.5 GO:0002188 translation reinitiation(GO:0002188)
0.2 1.1 GO:0033687 osteoblast proliferation(GO:0033687)
0.1 1.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.4 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.7 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.1 0.4 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.5 GO:0042308 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.1 0.7 GO:0034080 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 0.5 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 1.0 GO:0044211 CTP salvage(GO:0044211)
0.1 0.6 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.1 0.6 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 1.2 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.1 0.8 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.4 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 1.4 GO:1901655 cellular response to ketone(GO:1901655)
0.1 1.0 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.1 0.4 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 1.3 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 0.3 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.1 0.5 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 0.6 GO:2000290 regulation of myotome development(GO:2000290)
0.1 0.5 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.1 0.5 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.1 1.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.3 GO:0045056 transcytosis(GO:0045056)
0.1 0.6 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.5 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.5 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.7 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:0048069 eye pigmentation(GO:0048069)
0.0 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.9 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.6 GO:0045116 protein neddylation(GO:0045116)
0.0 0.6 GO:0021979 hypothalamus cell differentiation(GO:0021979) limb morphogenesis(GO:0035108)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 0.2 GO:0046102 adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.0 2.1 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.4 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.6 GO:0006265 DNA topological change(GO:0006265)
0.0 1.3 GO:0048538 thymus development(GO:0048538)
0.0 1.1 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.1 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 2.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.6 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.2 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.0 0.6 GO:0033505 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 0.2 GO:0031179 peptide modification(GO:0031179)
0.0 0.1 GO:0071871 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.2 GO:1901998 toxin transport(GO:1901998)
0.0 0.6 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.5 GO:0006301 postreplication repair(GO:0006301)
0.0 0.3 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 0.4 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:2000639 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.2 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 0.3 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.3 GO:0032438 melanosome organization(GO:0032438)
0.0 0.3 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 1.3 GO:0031101 fin regeneration(GO:0031101)
0.0 0.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.7 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.2 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.0 0.3 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.2 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.8 GO:0001666 response to hypoxia(GO:0001666)
0.0 0.3 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0033186 CAF-1 complex(GO:0033186)
0.2 0.9 GO:0031415 NatA complex(GO:0031415)
0.2 1.0 GO:1902636 kinociliary basal body(GO:1902636)
0.2 1.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 0.6 GO:0016600 flotillin complex(GO:0016600)
0.1 0.8 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.4 GO:0034709 methylosome(GO:0034709)
0.1 0.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.5 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.1 0.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.2 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.1 0.4 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 0.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 3.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.8 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 1.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.6 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.3 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 2.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.8 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.9 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.3 GO:0030496 midbody(GO:0030496)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0031082 BLOC complex(GO:0031082)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0072546 ER membrane protein complex(GO:0072546)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.3 1.1 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.2 0.8 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 1.2 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.1 0.8 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 1.0 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.7 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.5 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.3 GO:0030623 U5 snRNA binding(GO:0030623)
0.1 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.9 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 0.7 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.4 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1 0.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.4 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.3 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 1.1 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.6 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.6 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.6 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.8 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.7 GO:0019843 rRNA binding(GO:0019843)
0.0 0.6 GO:0031386 protein tag(GO:0031386)
0.0 0.4 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.5 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.3 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.8 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.5 GO:0048038 quinone binding(GO:0048038)
0.0 0.7 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0005035 death receptor activity(GO:0005035)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0043394 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.0 0.6 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.5 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.4 GO:0071617 lysophospholipid acyltransferase activity(GO:0071617)
0.0 1.6 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 1.3 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 1.2 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.6 GO:0000049 tRNA binding(GO:0000049)
0.0 0.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.1 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.1 GO:1903924 estradiol binding(GO:1903924)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 1.4 GO:0003714 transcription corepressor activity(GO:0003714)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.4 PID ATM PATHWAY ATM pathway
0.0 2.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.9 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 3.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 0.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein