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PRJEB1986: zebrafish developmental stages transcriptome

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Results for insm1a+insm1b

Z-value: 0.84

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Transcription factors associated with insm1a+insm1b

Gene Symbol Gene ID Gene Info
insm1b
ENSDARG00000053301 insulinoma-associated 1b
insm1a
ENSDARG00000091756 insulinoma-associated 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
insm1bdr11_v1_chr17_+_41463942_414639420.272.6e-01Click!
insm1adr11_v1_chr20_-_48485354_484853540.184.7e-01Click!

Activity profile of insm1a+insm1b motif

Sorted Z-values of insm1a+insm1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_4683325 2.94 ENSDART00000152771
si:ch211-255p10.3
si:ch211-255p10.3
chr24_+_23959487 2.80 ENSDART00000080487
hgd
homogentisate 1,2-dioxygenase
chr18_+_642889 2.63 ENSDART00000189007
CABZ01078320.1

chr5_+_36932718 2.31 ENSDART00000037879
crx
cone-rod homeobox
chr7_+_73397283 2.18 ENSDART00000174390
CABZ01081780.1

chr8_+_1082100 2.03 ENSDART00000149276
lzts3b
leucine zipper, putative tumor suppressor family member 3b
chr1_-_21599219 1.99 ENSDART00000148327
adamtsl7
ADAMTS-like 7
chr8_-_20838342 1.95 ENSDART00000141345
si:ch211-133l5.7
si:ch211-133l5.7
chr21_+_25660613 1.92 ENSDART00000134017
si:dkey-17e16.15
si:dkey-17e16.15
chr1_+_19332837 1.86 ENSDART00000078594
tyrp1b
tyrosinase-related protein 1b
chr12_-_45349849 1.86 ENSDART00000183036
CABZ01068367.1
Danio rerio uncharacterized LOC100332446 (LOC100332446), mRNA.
chr9_-_42989297 1.78 ENSDART00000126871
ttn.2
titin, tandem duplicate 2
chr5_-_51830997 1.71 ENSDART00000163616
homer1b
homer scaffolding protein 1b
chr11_+_25619892 1.64 ENSDART00000146647
ENSDART00000033702
comtb
catechol-O-methyltransferase b
chr9_-_23944470 1.64 ENSDART00000138754
col6a3
collagen, type VI, alpha 3
chr23_-_21797517 1.61 ENSDART00000110041
lrrc38a
leucine rich repeat containing 38a
chr6_-_46875310 1.57 ENSDART00000154442
igfn1.3
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr7_+_23515966 1.41 ENSDART00000186893
ENSDART00000186189
zgc:109889
zgc:109889
chr9_+_53719230 1.40 ENSDART00000165827
PCDH8
si:ch211-199f5.1
chr4_-_17409533 1.39 ENSDART00000011943
pah
phenylalanine hydroxylase
chr9_+_4429593 1.34 ENSDART00000184855
FP015810.1

chr25_-_28443607 1.33 ENSDART00000157243
ptprz1a
protein tyrosine phosphatase, receptor-type, Z polypeptide 1a
chr2_+_1202347 1.31 ENSDART00000075837
CABZ01084566.1

chr8_-_37391372 1.30 ENSDART00000190407
ENSDART00000009569
slc12a5b
solute carrier family 12 (potassium/chloride transporter), member 5b
chr17_-_52579709 1.20 ENSDART00000156806
rps6kl1
ribosomal protein S6 kinase-like 1
chr4_+_13733838 1.17 ENSDART00000067166
ENSDART00000133157
cntn1b
contactin 1b
chr5_-_16274058 1.16 ENSDART00000090684
kremen1
kringle containing transmembrane protein 1
chr19_+_1097393 1.15 ENSDART00000168218
CABZ01111953.1

chr5_+_43006422 1.09 ENSDART00000009182
aqp3a
aquaporin 3a
chr22_-_906757 1.06 ENSDART00000193182
FP016205.1

chr10_+_21801030 1.06 ENSDART00000160881
ENSDART00000187969
pcdh1g30
protocadherin 1 gamma 30
chr10_+_41549819 1.05 ENSDART00000114210
CABZ01049847.1

chr18_+_50278858 1.03 ENSDART00000014582
si:dkey-105e17.1
si:dkey-105e17.1
chr18_+_5137241 1.02 ENSDART00000159601
serpini1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr13_-_49666615 1.01 ENSDART00000148083
tomm20a
translocase of outer mitochondrial membrane 20
chr17_+_9310259 1.00 ENSDART00000186158
ENSDART00000190329
NPAS3
neuronal PAS domain protein 3
chr17_-_4318393 0.97 ENSDART00000167995
ENSDART00000153824
napba
N-ethylmaleimide-sensitive factor attachment protein, beta a
chr8_-_18899427 0.97 ENSDART00000079840
rorca
RAR-related orphan receptor C a
chr24_+_23959107 0.95 ENSDART00000180036
hgd
homogentisate 1,2-dioxygenase
chr9_-_4598883 0.92 ENSDART00000171927
galnt13
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13
chr23_+_19594608 0.91 ENSDART00000134865
slmapb
sarcolemma associated protein b
chr12_-_48992527 0.89 ENSDART00000169696
CDHR1 (1 of many)
cadherin related family member 1
chr2_+_58221163 0.87 ENSDART00000157939
FO704813.1

chr22_+_17536989 0.84 ENSDART00000149531
hnrnpm
heterogeneous nuclear ribonucleoprotein M
chr21_+_26612777 0.83 ENSDART00000142667
esrra
estrogen-related receptor alpha
chr3_-_49566364 0.83 ENSDART00000161507
zgc:153426
zgc:153426
chr4_+_7888047 0.82 ENSDART00000104676
camk1da
calcium/calmodulin-dependent protein kinase 1Da
chr2_-_28682476 0.82 ENSDART00000190178
dhcr7
7-dehydrocholesterol reductase
chr14_-_4076480 0.81 ENSDART00000059231
enpp6
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr20_+_1996202 0.80 ENSDART00000184143
CABZ01092781.1

chr10_+_44940693 0.80 ENSDART00000157515
cnnm4a
cyclin and CBS domain divalent metal cation transport mediator 4a
chr6_-_39051319 0.77 ENSDART00000155093
tns2b
tensin 2b
chr21_+_30673183 0.77 ENSDART00000144652
clcn5a
chloride channel, voltage-sensitive 5a
chr12_+_4573696 0.77 ENSDART00000152534
si:dkey-94f20.4
si:dkey-94f20.4
chr15_-_37921998 0.76 ENSDART00000193597
ENSDART00000181443
ENSDART00000168790
si:dkey-238d18.5
si:dkey-238d18.5
chr21_+_11105007 0.73 ENSDART00000128859
ENSDART00000193105
prlra
prolactin receptor a
chr15_-_33925851 0.69 ENSDART00000187807
ENSDART00000187780
mag
myelin associated glycoprotein
chr25_-_19661198 0.68 ENSDART00000149641
atp2b1b
ATPase plasma membrane Ca2+ transporting 1b
chr18_+_45573251 0.68 ENSDART00000191309
kifc3
kinesin family member C3
chr24_-_2917540 0.67 ENSDART00000164776
fam69c
family with sequence similarity 69, member C
chr12_+_47280839 0.67 ENSDART00000187574
RYR2
ryanodine receptor 2
chr8_-_49705058 0.65 ENSDART00000083760
frmd3
FERM domain containing 3
chr8_-_14484599 0.64 ENSDART00000057644
lhx4
LIM homeobox 4
chr1_+_2112726 0.63 ENSDART00000131714
ENSDART00000138396
mbnl2
muscleblind-like splicing regulator 2
chr25_-_35113891 0.62 ENSDART00000190724
zgc:165555
zgc:165555
chr7_-_72261721 0.62 ENSDART00000172229
RASGRP2
RAS guanyl releasing protein 2
chr10_-_41157135 0.61 ENSDART00000134851
aak1b
AP2 associated kinase 1b
chr1_+_55002583 0.60 ENSDART00000037250
si:ch211-196h16.12
si:ch211-196h16.12
chr9_-_1434484 0.59 ENSDART00000093412
osbpl6
oxysterol binding protein-like 6
chr13_+_45524475 0.58 ENSDART00000074567
ENSDART00000019113
maco1b
macoilin 1b
chr18_+_45573416 0.55 ENSDART00000132184
ENSDART00000145288
kifc3
kinesin family member C3
chr6_+_8129543 0.54 ENSDART00000011724
klf1
Kruppel-like factor 1 (erythroid)
chr3_+_49043917 0.54 ENSDART00000158212
zgc:92161
zgc:92161
chr14_-_14566417 0.51 ENSDART00000159056
si:dkey-27i16.2
si:dkey-27i16.2
chr24_-_10394277 0.50 ENSDART00000127568
ankha
ANKH inorganic pyrophosphate transport regulator a
chr2_+_15100742 0.48 ENSDART00000027171
f3b
coagulation factor IIIb
chr20_-_487783 0.46 ENSDART00000162218
col10a1b
collagen, type X, alpha 1b
chr25_-_21085661 0.45 ENSDART00000099355
prr5a
proline rich 5a (renal)
chr2_+_24507597 0.45 ENSDART00000133109
rps28
ribosomal protein S28
chr13_+_36680564 0.44 ENSDART00000136030
ENSDART00000006923
atp5s
ATP synthase, H+ transporting, mitochondrial F0 complex subunit s
chr15_+_31471808 0.44 ENSDART00000110078
or102-3
odorant receptor, family C, subfamily 102, member 3
chr19_+_9305964 0.44 ENSDART00000136241
si:ch73-15n24.1
si:ch73-15n24.1
chr2_-_16216568 0.43 ENSDART00000173758
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr9_+_38427572 0.43 ENSDART00000108860
CYP27A1 (1 of many)
zgc:136333
chr25_-_13659249 0.42 ENSDART00000045488
csnk2a2b
casein kinase 2, alpha prime polypeptide b
chr13_+_30951155 0.42 ENSDART00000057469
ENSDART00000162254
vstm4a
V-set and transmembrane domain containing 4a
chr23_-_452365 0.42 ENSDART00000146776
tspan2b
tetraspanin 2b
chr13_+_23176330 0.42 ENSDART00000168351
sorbs1
sorbin and SH3 domain containing 1
chr3_-_8765165 0.41 ENSDART00000191131
CABZ01058333.1

chr14_-_6402769 0.41 ENSDART00000121552
slc44a1b
solute carrier family 44 (choline transporter), member 1b
chr25_+_32496877 0.40 ENSDART00000132698
ctdspl2a
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2a
chr7_-_6355459 0.39 ENSDART00000172898
CU457819.1

chr21_+_40261187 0.39 ENSDART00000142204
si:ch211-218m3.11
si:ch211-218m3.11
chr19_+_2726819 0.38 ENSDART00000187122
ENSDART00000112414
rapgef5a
Rap guanine nucleotide exchange factor (GEF) 5a
chr13_+_41819817 0.38 ENSDART00000185778
CABZ01066611.1

chr1_-_40341306 0.36 ENSDART00000190649
maml3
mastermind-like transcriptional coactivator 3
chr5_-_30984271 0.36 ENSDART00000051392
spns3
spinster homolog 3 (Drosophila)
chr11_-_40101246 0.35 ENSDART00000161083
tnfrsf9b
tumor necrosis factor receptor superfamily, member 9b
chr10_-_105100 0.35 ENSDART00000145716
ttc3
tetratricopeptide repeat domain 3
chr15_-_19128705 0.34 ENSDART00000152428
arhgap32a
Rho GTPase activating protein 32a
chr3_+_17346502 0.34 ENSDART00000187786
ENSDART00000131584
si:ch211-210g13.5
si:ch211-210g13.5
chr9_-_30160897 0.34 ENSDART00000143986
abi3bpa
ABI family, member 3 (NESH) binding protein a
chr4_+_75458537 0.33 ENSDART00000166278
si:ch211-266c8.1
si:ch211-266c8.1
chr8_+_41453691 0.32 ENSDART00000061144
arpc5la
actin related protein 2/3 complex, subunit 5-like, a
chr7_+_31871830 0.32 ENSDART00000139899
mybpc3
myosin binding protein C, cardiac
chr14_+_42172677 0.32 ENSDART00000148544
pcdh18b
protocadherin 18b
chr19_+_9032073 0.30 ENSDART00000127755
ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr17_+_6793001 0.30 ENSDART00000030773
foxo3a
forkhead box O3A
chr17_+_45454943 0.28 ENSDART00000074838
kcnk3b
potassium channel, subfamily K, member 3b
chr3_-_61592417 0.28 ENSDART00000155082
nptx2a
neuronal pentraxin 2a
chr13_-_24874950 0.27 ENSDART00000077775
kat6b
K(lysine) acetyltransferase 6B
chr18_-_41211980 0.26 ENSDART00000171431
zbtb38
zinc finger and BTB domain containing 38
chr10_+_15106808 0.26 ENSDART00000141588
scpp8
secretory calcium-binding phosphoprotein 8
chr13_+_40034176 0.26 ENSDART00000189797
golga7bb
golgin A7 family, member Bb
chr4_+_76466751 0.25 ENSDART00000164709
zgc:153116
zgc:153116
chr25_+_32496723 0.24 ENSDART00000087978
ctdspl2a
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2a
chr1_-_18803919 0.23 ENSDART00000020970
pgm2
phosphoglucomutase 2
chr7_-_72423666 0.23 ENSDART00000191214
rph3ab
rabphilin 3A homolog (mouse), b
chr18_+_48608366 0.23 ENSDART00000151229
kcnj5
potassium inwardly-rectifying channel, subfamily J, member 5
chr7_+_22585447 0.22 ENSDART00000149144
chrnb1l
cholinergic receptor, nicotinic, beta 1 (muscle) like
chr2_+_24507770 0.22 ENSDART00000154802
ENSDART00000052063
rps28
ribosomal protein S28
chr19_-_19556778 0.22 ENSDART00000164060
tax1bp1a
Tax1 (human T-cell leukemia virus type I) binding protein 1a
chr6_+_9421279 0.21 ENSDART00000161036
kalrnb
kalirin RhoGEF kinase b
chr21_+_5800306 0.20 ENSDART00000020603
ccng2
cyclin G2
chr14_-_30876299 0.20 ENSDART00000180305
ubl3b
ubiquitin-like 3b
chr7_-_54320088 0.19 ENSDART00000172396
fadd
Fas (tnfrsf6)-associated via death domain
chr3_+_55114097 0.19 ENSDART00000121686
hbbe1.1
hemoglobin beta embryonic-1.1
chr10_-_1180314 0.18 ENSDART00000114261
bmpr1bb
bone morphogenetic protein receptor, type IBb
chr12_+_30368145 0.18 ENSDART00000153454
ccdc186
si:ch211-225b10.4
chr5_-_37252111 0.17 ENSDART00000185110
lrch2
leucine-rich repeats and calponin homology (CH) domain containing 2
chr5_+_50371951 0.17 ENSDART00000184488
ENSDART00000171295
slf1
SMC5-SMC6 complex localization factor 1
chr10_+_6383270 0.16 ENSDART00000170548
zgc:114200
zgc:114200
chr12_+_46740584 0.16 ENSDART00000171563
plaub
plasminogen activator, urokinase b
chr19_-_33996277 0.14 ENSDART00000159384
elmo1
engulfment and cell motility 1 (ced-12 homolog, C. elegans)
chr17_+_53425037 0.14 ENSDART00000154983
fabp10b
fatty acid binding protein 10b, liver basic
chr3_+_20001608 0.13 ENSDART00000137944
asb16
ankyrin repeat and SOCS box containing 16
chr14_+_8504410 0.13 ENSDART00000123364
vegfba
vascular endothelial growth factor Ba
chr23_+_16430559 0.13 ENSDART00000112436
ntsr1
neurotensin receptor 1 (high affinity)
chr21_-_35534401 0.12 ENSDART00000112308
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr24_-_33873451 0.11 ENSDART00000159840
asic1c
acid-sensing (proton-gated) ion channel 1c
chr3_+_40672242 0.10 ENSDART00000188494
BX649559.2

chr2_+_53880669 0.10 ENSDART00000191655
CABZ01050238.1

chr7_+_73649686 0.09 ENSDART00000185589
PCP4L1
si:dkey-46i9.1
chr13_+_18331509 0.09 ENSDART00000181918
zgc:110319
zgc:110319
chr4_+_71018579 0.08 ENSDART00000186727
si:dkeyp-80d11.10
si:dkeyp-80d11.10
chr14_-_49992709 0.08 ENSDART00000159988
fam193b
family with sequence similarity 193, member B
chr4_+_42412212 0.08 ENSDART00000163299
si:dkey-16p6.1
si:dkey-16p6.1
chr21_+_6197223 0.08 ENSDART00000147716
si:dkey-93m18.3
si:dkey-93m18.3
chr4_-_5597802 0.07 ENSDART00000136229
vegfab
vascular endothelial growth factor Ab
chr24_-_28306484 0.06 ENSDART00000148618
prkag2a
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr11_-_26040594 0.05 ENSDART00000144115
kaznb
kazrin, periplakin interacting protein b
chr24_-_6260333 0.05 ENSDART00000136041
myo3a
myosin IIIA
chr4_+_90048 0.05 ENSDART00000166440
lrp6
low density lipoprotein receptor-related protein 6
chr8_-_23684659 0.05 ENSDART00000136865
cfp
complement factor properdin
chr15_-_3078600 0.05 ENSDART00000172842
fndc3a
fibronectin type III domain containing 3A
chr3_+_55122662 0.04 ENSDART00000128380
hbbe1.2
hemoglobin beta embryonic-1.2
chr20_+_1834262 0.04 ENSDART00000185316
CABZ01065423.1

chr12_-_47774807 0.04 ENSDART00000193831
LO017725.1

chr1_+_55452892 0.04 ENSDART00000122508
CR788255.1

chr22_+_344763 0.04 ENSDART00000181934
CU914780.1

chr20_-_40760217 0.02 ENSDART00000101007
cx34.5
connexin 34.5
chr6_+_3166941 0.02 ENSDART00000168912
ptprfa
protein tyrosine phosphatase, receptor type, f, a
chr3_-_31845816 0.02 ENSDART00000157028
map3k3
mitogen-activated protein kinase kinase kinase 3
chr14_-_28567845 0.01 ENSDART00000126095
insb
preproinsulin b
chr7_-_3470451 0.01 ENSDART00000173387
si:ch211-285c6.6
si:ch211-285c6.6

Network of associatons between targets according to the STRING database.

First level regulatory network of insm1a+insm1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.1 GO:0006559 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.4 1.9 GO:0097066 response to thyroid hormone(GO:0097066)
0.3 0.8 GO:0019695 choline metabolic process(GO:0019695)
0.2 1.7 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 1.0 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.2 1.6 GO:0019336 phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.2 1.2 GO:0048903 anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.2 0.8 GO:2000815 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.2 0.7 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 2.9 GO:0006825 copper ion transport(GO:0006825)
0.1 2.0 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 0.6 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 1.8 GO:0048769 sarcomerogenesis(GO:0048769)
0.1 1.4 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.3 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 0.6 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.2 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 1.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.8 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.0 2.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.8 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.8 GO:0042446 hormone biosynthetic process(GO:0042446)
0.0 1.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.2 GO:0017145 stem cell division(GO:0017145)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.8 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.2 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.5 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.2 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.2 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 1.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.2 0.7 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.2 1.9 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 1.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.4 GO:0031209 SCAR complex(GO:0031209)
0.1 2.9 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 0.8 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.3 GO:0001650 fibrillar center(GO:0001650)
0.0 0.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0016586 RSC complex(GO:0016586)
0.0 0.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 3.7 GO:0014069 postsynaptic density(GO:0014069)
0.0 2.7 GO:0000786 nucleosome(GO:0000786)
0.0 1.6 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 1.6 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.8 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.9 GO:0016531 copper chaperone activity(GO:0016531)
0.4 1.6 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.3 1.7 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.3 1.1 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.2 0.7 GO:0004925 prolactin receptor activity(GO:0004925)
0.2 1.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.2 1.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 1.4 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.5 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 1.5 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.3 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.1 1.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 2.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.3 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 0.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.8 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 1.6 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 2.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.8 GO:0010857 calcium-dependent protein kinase activity(GO:0010857)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.8 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.2 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0002020 protease binding(GO:0002020)
0.0 2.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.0 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.7 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 5.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits