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PRJEB1986: zebrafish developmental stages transcriptome

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Results for irf1a

Z-value: 0.85

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Transcription factors associated with irf1a

Gene Symbol Gene ID Gene Info
irf1a
ENSDARG00000043492 interferon regulatory factor 1a

Activity profile of irf1a motif

Sorted Z-values of irf1a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_5523690 1.59 ENSDART00000027304
mapk12b
mitogen-activated protein kinase 12b
chr9_+_37754845 1.29 ENSDART00000100592
pdia5
protein disulfide isomerase family A, member 5
chr19_+_7115223 1.15 ENSDART00000001359
psmb12
proteasome subunit beta 12
chr3_-_12026741 1.01 ENSDART00000132238
cfap70
cilia and flagella associated protein 70
chr3_-_36127234 1.00 ENSDART00000130917
coil
coilin p80
chr4_-_12795030 0.99 ENSDART00000150427
b2m
beta-2-microglobulin
chr17_+_25833947 0.96 ENSDART00000044328
ENSDART00000154604
acss1
acyl-CoA synthetase short chain family member 1
chr15_-_16384184 0.91 ENSDART00000154504
fam222bb
family with sequence similarity 222, member Bb
chr14_+_36414856 0.87 ENSDART00000123343
ENSDART00000015761
neil3
nei-like DNA glycosylase 3
chr21_-_26715270 0.84 ENSDART00000053794
banf1
barrier to autointegration factor 1
chr3_-_18274691 0.84 ENSDART00000161140
BX649434.3

chr2_+_42294944 0.83 ENSDART00000140599
ENSDART00000178811
ftr06
finTRIM family, member 6
chr25_-_27722309 0.82 ENSDART00000148121
zgc:153935
zgc:153935
chr1_-_7930679 0.82 ENSDART00000146090
si:dkey-79f11.10
si:dkey-79f11.10
chr4_-_46948863 0.78 ENSDART00000168835
si:dkey-16p6.1
si:dkey-16p6.1
chr13_+_30912385 0.78 ENSDART00000182642
drgx
dorsal root ganglia homeobox
chr2_-_42035250 0.75 ENSDART00000056460
ENSDART00000140788
gbp1
guanylate binding protein 1
chr23_+_642395 0.74 ENSDART00000186995
irf10
interferon regulatory factor 10
chr8_-_36469117 0.73 ENSDART00000111240
mhc2dab
major histocompatibility complex class II DAB gene
chr17_-_28811747 0.72 ENSDART00000001444
g2e3
G2/M-phase specific E3 ubiquitin protein ligase
chr2_+_24374669 0.71 ENSDART00000133818
nr2f6a
nuclear receptor subfamily 2, group F, member 6a
chr11_-_19775182 0.67 ENSDART00000037894
namptb
nicotinamide phosphoribosyltransferase b
chr7_+_22792895 0.67 ENSDART00000184407
rbm4.3
RNA binding motif protein 4.3
chr20_-_36408836 0.67 ENSDART00000076419
lbr
lamin B receptor
chr15_+_30323491 0.67 ENSDART00000048847
nos2b
nitric oxide synthase 2b, inducible
chr19_-_7115229 0.66 ENSDART00000001930
psmb13a
proteasome subunit beta 13a
chr11_-_20096018 0.66 ENSDART00000030420
ogfrl2
opioid growth factor receptor-like 2
chr12_+_6098713 0.66 ENSDART00000139054
sgms1
sphingomyelin synthase 1
chr13_+_30912117 0.66 ENSDART00000133138
drgx
dorsal root ganglia homeobox
chr14_-_25078569 0.62 ENSDART00000172802
ENSDART00000173345
ENSDART00000135004
matr3l1.1
matrin 3-like 1.1
chr10_-_210703 0.60 ENSDART00000059476
psmg1
proteasome (prosome, macropain) assembly chaperone 1
chr5_-_31856681 0.59 ENSDART00000187817
pkn3
protein kinase N3
chr15_+_2421432 0.58 ENSDART00000193772
hephl1a
hephaestin-like 1a
chr14_+_52481288 0.58 ENSDART00000169164
ENSDART00000159297
tcerg1a
transcription elongation regulator 1a (CA150)
chr22_-_10158038 0.58 ENSDART00000047444
rbck1
RanBP-type and C3HC4-type zinc finger containing 1
chr21_+_34929598 0.57 ENSDART00000135806
si:dkey-71d15.2
si:dkey-71d15.2
chr23_+_12454542 0.57 ENSDART00000182259
ENSDART00000193043
si:ch211-153a8.4
si:ch211-153a8.4
chr2_-_48539673 0.57 ENSDART00000168202
CR391991.4

chr2_+_42271830 0.56 ENSDART00000074027
ENSDART00000146444
ftr10
finTRIM family, member 10
chr16_-_11986321 0.56 ENSDART00000148666
ENSDART00000029121
usp5
ubiquitin specific peptidase 5 (isopeptidase T)
chr16_+_48631412 0.55 ENSDART00000154273
pbx2
pre-B-cell leukemia homeobox 2
chr11_-_30341431 0.55 ENSDART00000078378
cflara
CASP8 and FADD-like apoptosis regulator a
chr6_-_45869127 0.54 ENSDART00000062459
ENSDART00000180563
rbm19
RNA binding motif protein 19
chr10_-_42147318 0.54 ENSDART00000134890
dusp11
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
chr25_-_27722614 0.53 ENSDART00000190154
zgc:153935
zgc:153935
chr20_+_51199666 0.53 ENSDART00000169321
hsp90ab1
heat shock protein 90, alpha (cytosolic), class B member 1
chr22_+_10158502 0.53 ENSDART00000005869
rpp14
ribonuclease P/MRP 14 subunit
chr18_-_6534357 0.52 ENSDART00000192886
ddx11
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
chr5_-_31857345 0.51 ENSDART00000112546
pkn3
protein kinase N3
chr9_+_41459759 0.51 ENSDART00000132501
ENSDART00000100265
nemp2
nuclear envelope integral membrane protein 2
chr19_+_20178978 0.50 ENSDART00000145115
ENSDART00000151175
tra2a
transformer 2 alpha homolog
chr7_+_26049818 0.50 ENSDART00000173611
si:dkey-6n21.12
si:dkey-6n21.12
chr11_-_45385602 0.50 ENSDART00000166691
trappc10
trafficking protein particle complex 10
chr23_+_24604481 0.49 ENSDART00000146332
kansl2
KAT8 regulatory NSL complex subunit 2
chr25_-_31629095 0.49 ENSDART00000170673
ENSDART00000166930
lamb1a
laminin, beta 1a
chr3_+_29941777 0.48 ENSDART00000113889
ifi35
interferon-induced protein 35
chr23_+_20705849 0.48 ENSDART00000079538
ccdc30
coiled-coil domain containing 30
chr23_+_642001 0.47 ENSDART00000030643
ENSDART00000124850
irf10
interferon regulatory factor 10
chr19_-_15281996 0.46 ENSDART00000103784
edn2
endothelin 2
chr3_+_19336286 0.46 ENSDART00000111528
kri1
KRI1 homolog
chr15_-_21702317 0.46 ENSDART00000155824
IL4I1
si:dkey-40g16.6
chr10_-_1961576 0.44 ENSDART00000042441
tdgf1
teratocarcinoma-derived growth factor 1
chr3_-_37148594 0.44 ENSDART00000140855
mlx
MLX, MAX dimerization protein
chr16_+_26439939 0.44 ENSDART00000143073
trim35-28
tripartite motif containing 35-28
chr15_-_15227541 0.43 ENSDART00000184787
rrp8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr7_+_19600262 0.42 ENSDART00000007310
zgc:171731
zgc:171731
chr9_-_23765480 0.41 ENSDART00000027212
si:ch211-219a4.6
si:ch211-219a4.6
chr3_-_3398383 0.40 ENSDART00000047865
si:dkey-46g23.2
si:dkey-46g23.2
chr16_+_5901835 0.40 ENSDART00000060519
ulk4
unc-51 like kinase 4
chr3_+_15394428 0.39 ENSDART00000133168
atxn2l
ataxin 2-like
chr6_+_31684 0.39 ENSDART00000188853
ENSDART00000184553
CZQB01141835.2

chr16_+_29514473 0.39 ENSDART00000034102
ctss2.2
cathepsin S, ortholog 2, tandem duplicate 2
chr20_-_28638871 0.39 ENSDART00000184779
rgs6
regulator of G protein signaling 6
chr10_+_2899108 0.38 ENSDART00000147031
erap1a
endoplasmic reticulum aminopeptidase 1a
chr16_+_35379720 0.38 ENSDART00000170497
si:dkey-34d22.2
si:dkey-34d22.2
chr9_-_9960940 0.37 ENSDART00000092164
prmt2
protein arginine methyltransferase 2
chr14_-_48786708 0.37 ENSDART00000169730
si:ch211-199b20.3
si:ch211-199b20.3
chr5_+_38654215 0.37 ENSDART00000144473
si:dkey-58f10.14
si:dkey-58f10.14
chr1_-_52790724 0.35 ENSDART00000139577
ENSDART00000100937
patl1
protein associated with topoisomerase II homolog 1 (yeast)
chr23_+_36063599 0.34 ENSDART00000103147
hoxc12a
homeobox C12a
chr19_+_4066449 0.34 ENSDART00000162461
btr26
bloodthirsty-related gene family, member 26
chr4_+_59061652 0.34 ENSDART00000150447
znf1127
zinc finger protein 1127
chr3_+_8826905 0.33 ENSDART00000167474
ENSDART00000168088
si:dkeyp-30d6.2
si:dkeyp-30d6.2
chr18_-_6534516 0.33 ENSDART00000009217
ddx11
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
chr1_+_524388 0.32 ENSDART00000020327
mrpl16
mitochondrial ribosomal protein L16
chr7_-_2309236 0.32 ENSDART00000173356
si:dkey-187j14.8
si:dkey-187j14.8
chr1_+_524717 0.32 ENSDART00000102421
ENSDART00000184473
mrpl16
mitochondrial ribosomal protein L16
chr23_+_23485858 0.31 ENSDART00000114067
agrn
agrin
chr21_+_35328025 0.31 ENSDART00000136211
rars
arginyl-tRNA synthetase
chr4_+_43522945 0.30 ENSDART00000183921
ENSDART00000181832
si:dkeyp-53e4.4
si:dkeyp-53e4.4
chr4_-_50933168 0.30 ENSDART00000150296
si:ch211-208f21.3
si:ch211-208f21.3
chr23_-_12906228 0.30 ENSDART00000138807
ndnl2
necdin-like 2
chr3_+_1942219 0.30 ENSDART00000114520
zgc:165583
zgc:165583
chr7_-_30492018 0.29 ENSDART00000099639
ENSDART00000162705
ENSDART00000173663
adam10a
ADAM metallopeptidase domain 10a
chr4_-_17669881 0.29 ENSDART00000066997
dram1
DNA-damage regulated autophagy modulator 1
chr3_+_48473346 0.28 ENSDART00000166294
metrnl
meteorin, glial cell differentiation regulator-like
chr4_-_31993240 0.28 ENSDART00000167842
si:dkey-72l17.5
si:dkey-72l17.5
chr19_-_3742472 0.27 ENSDART00000162132
btr22
bloodthirsty-related gene family, member 22
chr9_+_23765587 0.27 ENSDART00000145120
si:ch211-219a4.3
si:ch211-219a4.3
chr16_-_51271962 0.27 ENSDART00000164021
ENSDART00000046420
serpinb1l1
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1
chr20_+_26683933 0.27 ENSDART00000139852
ENSDART00000077751
foxq1b
forkhead box Q1b
chr16_+_26439518 0.27 ENSDART00000041787
trim35-28
tripartite motif containing 35-28
chr9_-_20853439 0.27 ENSDART00000028247
ENSDART00000133321
gdap2
ganglioside induced differentiation associated protein 2
chr13_+_13681681 0.26 ENSDART00000057825
cfd
complement factor D (adipsin)
chr22_+_36902352 0.26 ENSDART00000036273
trim35-20
tripartite motif containing 35-20
chr4_-_31699842 0.26 ENSDART00000166400
si:dkey-265e15.5
si:dkey-265e15.5
chr4_+_3358383 0.26 ENSDART00000075320
nampta
nicotinamide phosphoribosyltransferase a
chr16_-_40459104 0.26 ENSDART00000032389
plekhf2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr4_+_35130622 0.25 ENSDART00000165372
si:dkey-279j5.1
si:dkey-279j5.1
chr4_+_70911498 0.25 ENSDART00000157674
si:dkey-16p6.1
si:dkey-16p6.1
chr15_+_45591669 0.25 ENSDART00000157459
atg16l1
ATG16 autophagy related 16-like 1 (S. cerevisiae)
chr1_-_58002973 0.25 ENSDART00000140390
si:ch211-114l13.9
si:ch211-114l13.9
chr22_+_32235922 0.25 ENSDART00000114531
ENSDART00000136125
rbm15b
RNA binding motif protein 15B
chr21_+_40695345 0.25 ENSDART00000143594
ccdc82
coiled-coil domain containing 82
chr22_+_1589407 0.25 ENSDART00000175704
si:ch211-255f4.11
si:ch211-255f4.11
chr21_+_8533533 0.25 ENSDART00000077924
FO834888.1

chr4_-_76079075 0.24 ENSDART00000158469
si:ch211-232d10.3
si:ch211-232d10.3
chr4_+_70967639 0.24 ENSDART00000159230
si:dkeyp-80d11.12
si:dkeyp-80d11.12
chr22_-_36926342 0.24 ENSDART00000151804
si:dkey-37m8.11
si:dkey-37m8.11
chr23_+_43668756 0.24 ENSDART00000112598
otud4
OTU deubiquitinase 4
chr1_-_8141135 0.24 ENSDART00000152295
FAM83G
si:dkeyp-9d4.4
chr3_-_48612078 0.24 ENSDART00000169923
ndel1b
nudE neurodevelopment protein 1-like 1b
chr10_-_34889053 0.23 ENSDART00000136966
ccdc169
coiled-coil domain containing 169
chr16_-_50952266 0.23 ENSDART00000165408
si:dkeyp-97a10.3
si:dkeyp-97a10.3
chr22_+_15979430 0.23 ENSDART00000189703
ENSDART00000192674
rc3h1a
ring finger and CCCH-type domains 1a
chr4_+_58240778 0.22 ENSDART00000181184
ENSDART00000192348
ENSDART00000189444
ENSDART00000164424
si:dkey-16p6.1
si:dkey-16p6.1
chr5_+_61799629 0.22 ENSDART00000113508
hnrnpul1l
heterogeneous nuclear ribonucleoprotein U-like 1 like
chr18_+_14684115 0.21 ENSDART00000108469
spata2l
spermatogenesis associated 2-like
chr4_+_34417403 0.21 ENSDART00000186032
ENSDART00000167909
si:ch211-246b8.2
si:ch211-246b8.2
chr5_+_36895860 0.21 ENSDART00000134493
srsf7a
serine/arginine-rich splicing factor 7a
chr5_+_13373593 0.21 ENSDART00000051668
ENSDART00000183883
ccl19a.2
chemokine (C-C motif) ligand 19a, tandem duplicate 2
chr9_+_34334156 0.21 ENSDART00000144272
pou2f1b
POU class 2 homeobox 1b
chr24_-_8730913 0.21 ENSDART00000187228
ENSDART00000082349
ENSDART00000186660
tfap2a
transcription factor AP-2 alpha
chr7_-_804515 0.21 ENSDART00000159359
rela
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr2_-_47904043 0.20 ENSDART00000185328
ENSDART00000126740
ftr22
finTRIM family, member 22
chr19_+_14115838 0.20 ENSDART00000192057
kdf1b
keratinocyte differentiation factor 1b
chr1_-_8000428 0.19 ENSDART00000133098
si:dkey-79f11.5
si:dkey-79f11.5
chr4_-_40008099 0.19 ENSDART00000165574
ENSDART00000171888
si:ch211-215p11.1
si:ch211-215p11.1
chr9_-_14273652 0.19 ENSDART00000135458
abcb6b
ATP-binding cassette, sub-family B (MDR/TAP), member 6b
chr4_-_31668228 0.19 ENSDART00000161639
ENSDART00000159931
si:dkey-16p6.1
si:dkey-16p6.1
chr25_+_245018 0.18 ENSDART00000155344
zgc:92481
zgc:92481
chr3_-_48980319 0.18 ENSDART00000165319
ftr42
finTRIM family, member 42
chr13_+_27328098 0.18 ENSDART00000037585
mb21d1
Mab-21 domain containing 1
chr14_+_22397251 0.18 ENSDART00000185239
ENSDART00000124072
ENSDART00000054977
atp7a
ATPase copper transporting alpha
chr4_-_75641117 0.17 ENSDART00000182165
si:dkey-71l4.2
si:dkey-71l4.2
chr7_-_54430505 0.17 ENSDART00000167905
ano1
anoctamin 1, calcium activated chloride channel
chr24_+_10310577 0.17 ENSDART00000141718
otulina
OTU deubiquitinase with linear linkage specificity a
chr13_-_7387390 0.17 ENSDART00000088322
si:dkey-45k15.1
si:dkey-45k15.1
chr4_+_70782916 0.16 ENSDART00000187960
si:dkey-16p6.1
si:dkey-16p6.1
chr4_+_34417798 0.16 ENSDART00000157757
si:ch211-246b8.2
si:ch211-246b8.2
chr5_+_51111766 0.16 ENSDART00000188552
pomt1
protein-O-mannosyltransferase 1
chr4_-_45028479 0.16 ENSDART00000143150
ENSDART00000076870
si:dkey-51d8.1
si:dkey-51d8.1
chr1_-_31140096 0.16 ENSDART00000172243
kcnq5b
potassium voltage-gated channel, KQT-like subfamily, member 5b
chr2_-_38287987 0.16 ENSDART00000185329
ENSDART00000061677
si:ch211-14a17.6
si:ch211-14a17.6
chr1_-_52447364 0.16 ENSDART00000140740
si:ch211-217k17.10
si:ch211-217k17.10
chr17_-_35361322 0.16 ENSDART00000019617
rsad2
radical S-adenosyl methionine domain containing 2
chr4_-_75511162 0.15 ENSDART00000157651
si:dkey-71l4.5
si:dkey-71l4.5
chr4_+_53115165 0.15 ENSDART00000157470
si:dkey-8o9.2
si:dkey-8o9.2
chr6_-_18121075 0.15 ENSDART00000171072
SEC14L1
si:dkey-237i9.1
chr4_+_33862438 0.15 ENSDART00000165044
si:dkey-28i19.3
si:dkey-28i19.3
chr4_+_8016457 0.15 ENSDART00000014036
optn
optineurin
chr4_-_76206413 0.15 ENSDART00000170738
si:ch211-106j21.5
si:ch211-106j21.5
chr15_+_15786160 0.14 ENSDART00000130670
ENSDART00000090939
tada2a
transcriptional adaptor 2A
chr2_+_49667767 0.14 ENSDART00000191013
ENSDART00000193757
ENSDART00000187134
ENSDART00000189100
BX323861.3

chr3_+_19446997 0.14 ENSDART00000079352
zgc:123297
zgc:123297
chr4_-_51693601 0.14 ENSDART00000189025
ENSDART00000185516
ENSDART00000189576
si:dkeyp-90h9.1
si:dkeyp-90h9.1
chr4_-_71177920 0.14 ENSDART00000158287
si:dkey-193i10.1
si:dkey-193i10.1
chr4_+_59841099 0.14 ENSDART00000144806
si:dkey-196n19.2
si:dkey-196n19.2
chr3_-_7997887 0.14 ENSDART00000172256
TRIM35 (1 of many)
si:ch211-175l6.2
chr5_+_38685089 0.13 ENSDART00000139743
si:dkey-58f10.10
si:dkey-58f10.10
chr22_-_6465060 0.13 ENSDART00000081687
zgc:172133
zgc:172133
chr4_+_5842433 0.13 ENSDART00000124085
ENSDART00000179848
usp18
ubiquitin specific peptidase 18
chr20_-_31497300 0.13 ENSDART00000046841
sash1a
SAM and SH3 domain containing 1a
chr4_-_31699147 0.13 ENSDART00000187481
ENSDART00000182491
ENSDART00000187359
si:dkey-16p6.1
si:dkey-16p6.1
chr19_+_7938121 0.13 ENSDART00000140053
ENSDART00000146649
si:dkey-266f7.5
si:dkey-266f7.5
chr4_-_75616197 0.13 ENSDART00000157778
si:dkey-71l4.3
si:dkey-71l4.3
chr7_+_66884291 0.13 ENSDART00000187499
sbf2
SET binding factor 2
chr3_+_36127287 0.12 ENSDART00000058605
ENSDART00000182500
scpep1
serine carboxypeptidase 1
chr18_-_14901437 0.12 ENSDART00000145842
ENSDART00000008035
trabd
TraB domain containing
chr15_+_20352123 0.12 ENSDART00000011030
ENSDART00000163532
ENSDART00000169537
ENSDART00000161047
il15l
interleukin 15, like
chr22_-_11520405 0.12 ENSDART00000063157
slc26a11
solute carrier family 26 (anion exchanger), member 11
chr16_-_43344859 0.11 ENSDART00000058680
psma2
proteasome subunit alpha 2
chr8_-_12867128 0.11 ENSDART00000142201
slc2a6
solute carrier family 2 (facilitated glucose transporter), member 6
chr7_+_66884570 0.11 ENSDART00000082664
sbf2
SET binding factor 2
chr1_-_49530615 0.11 ENSDART00000113315
si:ch211-281g13.5
si:ch211-281g13.5
chr4_-_60916298 0.11 ENSDART00000142335
si:dkey-196n19.2
si:dkey-196n19.2
chr10_+_40623414 0.11 ENSDART00000187616
zgc:172131
zgc:172131
chr4_-_51692811 0.11 ENSDART00000159625
si:dkeyp-90h9.1
si:dkeyp-90h9.1
chr9_+_22631672 0.10 ENSDART00000101770
ENSDART00000126015
ENSDART00000145005
etv5a
ets variant 5a
chr4_-_64123545 0.10 ENSDART00000170040
BX914205.2

chr6_-_1566581 0.10 ENSDART00000192993
trim107
tripartite motif containing 107
chr4_-_25215968 0.10 ENSDART00000066932
ENSDART00000066933
itih2
inter-alpha-trypsin inhibitor heavy chain 2
chr19_-_7706926 0.10 ENSDART00000151270
si:dkey-204a24.11
si:dkey-204a24.11
chr22_+_1502561 0.10 ENSDART00000159973
AL954741.3

chr3_-_367283 0.09 ENSDART00000155936
ENSDART00000161964
ENSDART00000158560
ENSDART00000135595
ENSDART00000145890
mhc1zaa
major histocompatibility complex class I ZAA
chr19_+_2275019 0.09 ENSDART00000136138
itgb8
integrin, beta 8
chr18_+_50525109 0.09 ENSDART00000098390
ubl7b
ubiquitin-like 7b (bone marrow stromal cell-derived)
chr15_-_591308 0.09 ENSDART00000153884
si:ch73-144d13.5
si:ch73-144d13.5
chr8_-_19051906 0.09 ENSDART00000089024
sema6bb
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb
chr6_+_9793791 0.09 ENSDART00000149896
als2b
amyotrophic lateral sclerosis 2b (juvenile)

Network of associatons between targets according to the STRING database.

First level regulatory network of irf1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.2 1.0 GO:0030576 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.2 0.5 GO:0071635 transforming growth factor beta activation(GO:0036363) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635)
0.2 1.0 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.1 0.4 GO:0090008 hypoblast development(GO:0090008)
0.1 0.6 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 0.7 GO:0030823 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.3 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.1 0.5 GO:0060585 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.2 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.1 0.5 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.7 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.5 GO:0055016 hypochord development(GO:0055016)
0.1 0.5 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 0.4 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 0.4 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 1.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.3 GO:0039694 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.1 0.6 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.7 GO:0051131 proteasome assembly(GO:0043248) chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.2 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.1 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.8 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.7 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.8 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.9 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 0.2 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 0.6 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 0.3 GO:0039014 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.0 GO:0001562 response to protozoan(GO:0001562) TRIF-dependent toll-like receptor signaling pathway(GO:0035666) defense response to protozoan(GO:0042832) regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.0 0.6 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.1 GO:0048662 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 0.5 GO:0048546 digestive tract morphogenesis(GO:0048546)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0005880 nuclear microtubule(GO:0005880)
0.1 0.5 GO:1990071 TRAPPII protein complex(GO:1990071)
0.1 0.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.7 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.4 GO:0042611 MHC protein complex(GO:0042611)
0.1 1.7 GO:0005839 proteasome core complex(GO:0005839)
0.1 1.0 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 2.0 GO:0030496 midbody(GO:0030496)
0.0 1.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.5 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.5 GO:0030686 90S preribosome(GO:0030686)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.2 GO:0016607 nuclear speck(GO:0016607)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0030620 U2 snRNA binding(GO:0030620)
0.2 1.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.7 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.5 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.1 0.3 GO:0015462 protein-transmembrane transporting ATPase activity(GO:0015462)
0.1 1.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.7 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.3 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.1 0.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.9 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 1.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 1.2 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.6 GO:0070628 proteasome binding(GO:0070628)
0.0 0.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.4 GO:0070697 activin receptor binding(GO:0070697)
0.0 0.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.7 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.6 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.1 GO:0016504 peptidase activator activity(GO:0016504) endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0043236 laminin binding(GO:0043236)
0.0 0.6 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.6 GO:0005178 integrin binding(GO:0005178)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.9 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 1.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.8 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 2.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling