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PRJEB1986: zebrafish developmental stages transcriptome

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Results for irf6

Z-value: 0.22

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Transcription factors associated with irf6

Gene Symbol Gene ID Gene Info
irf6
ENSDARG00000101986 interferon regulatory factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
irf6dr11_v1_chr22_+_1170294_1170295-0.272.6e-01Click!

Activity profile of irf6 motif

Sorted Z-values of irf6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_21702317 0.30 ENSDART00000155824
IL4I1
si:dkey-40g16.6
chr19_-_6303099 0.22 ENSDART00000133371
pou2f2a
POU class 2 homeobox 2a
chr6_-_10728057 0.19 ENSDART00000002247
sp3b
Sp3b transcription factor
chr7_-_8881514 0.19 ENSDART00000081620
vax2
ventral anterior homeobox 2
chr12_+_16452575 0.16 ENSDART00000058665
kif20bb
kinesin family member 20Bb
chr12_+_16452912 0.15 ENSDART00000192467
kif20bb
kinesin family member 20Bb
chr7_+_56472585 0.14 ENSDART00000135259
ENSDART00000073596
ist1
increased sodium tolerance 1 homolog (yeast)
chr16_-_46766153 0.14 ENSDART00000115244
MEX3A
mex-3 RNA binding family member A
chr18_+_44532370 0.13 ENSDART00000086952
st14a
suppression of tumorigenicity 14 (colon carcinoma) a
chr16_+_19637384 0.11 ENSDART00000184773
ENSDART00000191895
ENSDART00000182020
ENSDART00000135359
macc1
metastasis associated in colon cancer 1
chr3_-_4501026 0.10 ENSDART00000163052
zgc:162198
zgc:162198
chr18_+_17624295 0.10 ENSDART00000151865
ENSDART00000190408
ENSDART00000189204
ENSDART00000188894
ENSDART00000033762
ENSDART00000193471
nlrc5
NLR family, CARD domain containing 5
chr18_+_44532883 0.10 ENSDART00000121994
st14a
suppression of tumorigenicity 14 (colon carcinoma) a
chr17_-_30666037 0.09 ENSDART00000156509
alkal2b
ALK and LTK ligand 2b
chr7_+_69187585 0.07 ENSDART00000160499
ENSDART00000166258
marveld3
MARVEL domain containing 3
chr9_-_23765480 0.07 ENSDART00000027212
si:ch211-219a4.6
si:ch211-219a4.6
chr17_-_22552678 0.06 ENSDART00000079401
si:ch211-125o16.4
si:ch211-125o16.4
chr10_+_28160265 0.06 ENSDART00000022484
rnft1
ring finger protein, transmembrane 1
chr14_+_33329761 0.05 ENSDART00000161138
sowahd
sosondowah ankyrin repeat domain family d
chr19_-_15420678 0.05 ENSDART00000151454
ENSDART00000027697
serinc2
serine incorporator 2
chr20_-_3911546 0.05 ENSDART00000169787
cnksr3
cnksr family member 3
chr11_-_30508843 0.03 ENSDART00000101667
ENSDART00000179930
map4k3a
mitogen-activated protein kinase kinase kinase kinase 3a
chr2_-_37140423 0.03 ENSDART00000144220
tspan37
tetraspanin 37
chr12_-_16452200 0.02 ENSDART00000037601
rpp30
ribonuclease P/MRP 30 subunit
chr8_+_47897734 0.01 ENSDART00000140266
mfn2
mitofusin 2
chr21_+_21010786 0.01 ENSDART00000079692
ndr1
nodal-related 1
chr16_+_27383717 0.01 ENSDART00000132329
ENSDART00000136256
stx17
syntaxin 17
chr18_+_44532199 0.01 ENSDART00000135386
st14a
suppression of tumorigenicity 14 (colon carcinoma) a

Network of associatons between targets according to the STRING database.

First level regulatory network of irf6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.0 0.1 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.1 GO:0070376 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.0 0.1 GO:1904292 regulation of ERAD pathway(GO:1904292)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0043034 costamere(GO:0043034)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)