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PRJEB1986: zebrafish developmental stages transcriptome

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Results for isl1+isl1l

Z-value: 0.77

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Transcription factors associated with isl1+isl1l

Gene Symbol Gene ID Gene Info
isl1
ENSDARG00000004023 ISL LIM homeobox 1
isl1l
ENSDARG00000021055 islet1, like
isl1l
ENSDARG00000110204 islet1, like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
isl1dr11_v1_chr5_-_40734045_407340450.233.4e-01Click!
isl1ldr11_v1_chr10_+_8680730_8680730-0.223.8e-01Click!

Activity profile of isl1+isl1l motif

Sorted Z-values of isl1+isl1l motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_46941930 2.20 ENSDART00000056962
fbxo5
F-box protein 5
chr4_+_15968483 1.80 ENSDART00000101575
si:dkey-117n7.5
si:dkey-117n7.5
chr14_-_41478265 1.39 ENSDART00000149886
ENSDART00000016002
tspan7
tetraspanin 7
chr13_-_50624173 1.38 ENSDART00000184181
vox
ventral homeobox
chr12_-_13205854 1.37 ENSDART00000077829
pelo
pelota mRNA surveillance and ribosome rescue factor
chr14_-_17072736 1.33 ENSDART00000106333
phox2bb
paired-like homeobox 2bb
chr2_+_11685742 1.28 ENSDART00000138562
greb1l
growth regulation by estrogen in breast cancer-like
chr21_+_723998 1.28 ENSDART00000160956
oaz1b
ornithine decarboxylase antizyme 1b
chr4_+_5506952 1.24 ENSDART00000032857
ENSDART00000160222
mapk11
mitogen-activated protein kinase 11
chr2_-_17114852 1.24 ENSDART00000006549
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr4_-_5826320 1.22 ENSDART00000165354
foxm1
forkhead box M1
chr19_-_47570672 1.17 ENSDART00000112155
rrm2
ribonucleotide reductase M2 polypeptide
chr22_-_24984733 1.09 ENSDART00000142147
ENSDART00000187284
dnal4b
dynein, axonemal, light chain 4b
chr7_-_54679595 1.08 ENSDART00000165320
ccnd1
cyclin D1
chr8_+_8936912 1.08 ENSDART00000135958
si:dkey-83k24.5
si:dkey-83k24.5
chr13_-_50614639 1.05 ENSDART00000170527
vent
ventral expressed homeobox
chr11_-_18107447 1.04 ENSDART00000187376
qrich1
glutamine-rich 1
chr11_-_10850936 1.04 ENSDART00000091901
psmd14
proteasome 26S subunit, non-ATPase 14
chr24_+_18714212 1.04 ENSDART00000171181
cspp1a
centrosome and spindle pole associated protein 1a
chr21_-_22317920 1.03 ENSDART00000191083
ENSDART00000108701
gdpd4b
glycerophosphodiester phosphodiesterase domain containing 4b
chr15_-_23529945 1.03 ENSDART00000152543
hmbsb
hydroxymethylbilane synthase, b
chr2_+_10821579 1.01 ENSDART00000179694
glmna
glomulin, FKBP associated protein a
chr25_+_30131055 1.01 ENSDART00000152705
api5
apoptosis inhibitor 5
chr14_+_16287968 1.00 ENSDART00000106593
prpf19
pre-mRNA processing factor 19
chr5_+_23136544 1.00 ENSDART00000003428
ENSDART00000109340
ENSDART00000171039
ENSDART00000178821
prps1a
phosphoribosyl pyrophosphate synthetase 1A
chr6_-_18618106 0.97 ENSDART00000161562
znf207b
zinc finger protein 207, b
chr8_-_1051438 0.97 ENSDART00000067093
ENSDART00000170737
smyd1b
SET and MYND domain containing 1b
chr11_-_18017287 0.96 ENSDART00000155443
qrich1
glutamine-rich 1
chr13_+_15701849 0.96 ENSDART00000003517
trmt61a
tRNA methyltransferase 61A
chr19_+_42432625 0.96 ENSDART00000076938
pogza
pogo transposable element derived with ZNF domain a
chr3_-_23513155 0.95 ENSDART00000170200
BX682558.1

chr12_+_27034760 0.95 ENSDART00000181170
ENSDART00000153054
fbrs
fibrosin
chr6_+_22326624 0.93 ENSDART00000020333
rae1
ribonucleic acid export 1
chr5_+_25762271 0.92 ENSDART00000181323
tmem2
transmembrane protein 2
chr17_+_32343121 0.91 ENSDART00000156051
dhx32b
DEAH (Asp-Glu-Ala-His) box polypeptide 32b
chr8_+_48942470 0.91 ENSDART00000005464
ENSDART00000132035
rer1
retention in endoplasmic reticulum sorting receptor 1
chr16_+_53203370 0.90 ENSDART00000154669
si:ch211-269k10.2
si:ch211-269k10.2
chr23_+_31596441 0.89 ENSDART00000053534
tbpl1
TBP-like 1
chr6_-_53326421 0.88 ENSDART00000191740
gnb1b
guanine nucleotide binding protein (G protein), beta polypeptide 1b
chr2_+_10821127 0.87 ENSDART00000145770
ENSDART00000174629
ENSDART00000081094
glmna
glomulin, FKBP associated protein a
chr12_-_13205572 0.86 ENSDART00000152670
pelo
pelota mRNA surveillance and ribosome rescue factor
chr15_+_36309070 0.86 ENSDART00000157034
gmnc
geminin coiled-coil domain containing
chr7_+_756942 0.85 ENSDART00000152224
zgc:63470
zgc:63470
chr22_+_9922301 0.84 ENSDART00000105924
blf
bloody fingers
chr12_+_14149686 0.84 ENSDART00000123741
kbtbd2
kelch repeat and BTB (POZ) domain containing 2
chr20_+_34770197 0.84 ENSDART00000018304
mcm3
minichromosome maintenance complex component 3
chr11_-_14813029 0.83 ENSDART00000004920
ENSDART00000122645
sgta
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr4_-_15103646 0.83 ENSDART00000138183
ENSDART00000181044
nrf1
nuclear respiratory factor 1
chr11_-_438294 0.82 ENSDART00000040812
nuf2
NUF2, NDC80 kinetochore complex component, homolog
chr15_-_39969988 0.82 ENSDART00000146054
rps5
ribosomal protein S5
chr25_+_36292057 0.82 ENSDART00000152329
bmb
brambleberry
chr12_-_19028046 0.81 ENSDART00000142253
ENSDART00000078484
rangap1b
Ran GTPase activating protein 1b
chr4_+_9478500 0.81 ENSDART00000030738
lmf2b
lipase maturation factor 2b
chr15_-_44052927 0.81 ENSDART00000166209
wu:fb44b02
wu:fb44b02
chr11_+_6009984 0.79 ENSDART00000185680
gtpbp3
GTP binding protein 3, mitochondrial
chr22_+_438714 0.79 ENSDART00000136491
celsr2
cadherin, EGF LAG seven-pass G-type receptor 2
chr2_-_25140022 0.79 ENSDART00000134543
nceh1a
neutral cholesterol ester hydrolase 1a
chr3_-_58650057 0.78 ENSDART00000057640
dhrs7ca
dehydrogenase/reductase (SDR family) member 7Ca
chr22_+_9918872 0.77 ENSDART00000177953
blf
bloody fingers
chr6_+_16031189 0.75 ENSDART00000015333
gbx2
gastrulation brain homeobox 2
chr17_-_29271359 0.74 ENSDART00000104219
rcor1
REST corepressor 1
chr1_+_51475094 0.73 ENSDART00000146352
meis1a
Meis homeobox 1 a
chr7_+_36898850 0.73 ENSDART00000113342
tox3
TOX high mobility group box family member 3
chr7_+_38897836 0.72 ENSDART00000024330
creb3l1
cAMP responsive element binding protein 3-like 1
chr16_-_55259199 0.70 ENSDART00000161130
iqgap3
IQ motif containing GTPase activating protein 3
chr1_-_19079957 0.70 ENSDART00000141795
phox2ba
paired-like homeobox 2ba
chr1_+_41588170 0.70 ENSDART00000139175
si:dkey-56e3.2
si:dkey-56e3.2
chr7_+_24496894 0.70 ENSDART00000149994
nelfa
negative elongation factor complex member A
chr7_+_36035432 0.69 ENSDART00000179004
irx3a
iroquois homeobox 3a
chr12_+_13205955 0.69 ENSDART00000092906
ppp1cab
protein phosphatase 1, catalytic subunit, alpha isozyme b
chr9_-_35633827 0.69 ENSDART00000077745
zp2l1
zona pellucida glycoprotein 2, like 1
chr9_+_14152211 0.68 ENSDART00000148055
si:ch211-67e16.11
si:ch211-67e16.11
chr17_-_19535328 0.68 ENSDART00000077809
cyp26c1
cytochrome P450, family 26, subfamily C, polypeptide 1
chr7_-_18598661 0.67 ENSDART00000182109
DTX4
si:ch211-119e14.2
chr22_-_14115292 0.67 ENSDART00000105717
ENSDART00000165670
aox5
aldehyde oxidase 5
chr22_-_621888 0.66 ENSDART00000135829
srsf3b
serine/arginine-rich splicing factor 3b
chr5_-_36597612 0.65 ENSDART00000031270
ENSDART00000122098
rhogc
ras homolog gene family, member Gc
chr11_+_6010177 0.64 ENSDART00000170047
ENSDART00000022526
ENSDART00000161001
ENSDART00000188999
gtpbp3
GTP binding protein 3, mitochondrial
chr7_-_30174882 0.64 ENSDART00000110409
frmd5
FERM domain containing 5
chr3_-_58116314 0.63 ENSDART00000154901
si:ch211-256e16.6
si:ch211-256e16.6
chr20_+_25712276 0.62 ENSDART00000121585
ENSDART00000185772
cep135
centrosomal protein 135
chr1_+_59328030 0.62 ENSDART00000172464
CABZ01052576.1

chr15_+_888704 0.62 ENSDART00000182796
si:dkey-7i4.9
si:dkey-7i4.9
chr16_-_35415004 0.62 ENSDART00000170401
ENSDART00000157832
ENSDART00000170048
taf12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr16_+_9762261 0.61 ENSDART00000020654
psmd4b
proteasome 26S subunit, non-ATPase 4b
chr7_+_15871156 0.61 ENSDART00000145946
pax6b
paired box 6b
chr8_-_25033681 0.61 ENSDART00000003493
nfyal
nuclear transcription factor Y, alpha, like
chr10_+_7593185 0.60 ENSDART00000162617
ENSDART00000162590
ENSDART00000171744
ppp2cb
protein phosphatase 2, catalytic subunit, beta isozyme
chr10_-_1961576 0.60 ENSDART00000042441
tdgf1
teratocarcinoma-derived growth factor 1
chr10_+_32104305 0.59 ENSDART00000099880
wnt11r
wingless-type MMTV integration site family, member 11, related
chr20_+_25711718 0.58 ENSDART00000033436
cep135
centrosomal protein 135
chr22_-_26852516 0.57 ENSDART00000005829
gde1
glycerophosphodiester phosphodiesterase 1
chr19_-_30420602 0.56 ENSDART00000144121
ppp1r10
protein phosphatase 1, regulatory subunit 10
chr15_-_25518084 0.56 ENSDART00000158594
hif1al
hypoxia-inducible factor 1, alpha subunit, like
chr21_+_2506013 0.55 ENSDART00000162351
hmgcrb
3-hydroxy-3-methylglutaryl-CoA reductase b
chr7_-_71585065 0.55 ENSDART00000128678
mettl4
methyltransferase like 4
chr7_+_26998169 0.55 ENSDART00000128110
ENSDART00000101018
caprin1a
cell cycle associated protein 1a
chr5_-_68495224 0.55 ENSDART00000187955
ephb4a
eph receptor B4a
chr10_-_11353101 0.54 ENSDART00000092110
lin54
lin-54 DREAM MuvB core complex component
chr15_-_43625549 0.54 ENSDART00000168589
ctsc
cathepsin C
chr22_-_28644517 0.53 ENSDART00000189538
jagn1b
jagunal homolog 1b
chr21_+_26522571 0.53 ENSDART00000134617
adssl
adenylosuccinate synthase, like
chr20_-_22464250 0.53 ENSDART00000165904
pdgfra
platelet-derived growth factor receptor, alpha polypeptide
chr6_+_15268685 0.53 ENSDART00000128090
ENSDART00000154417
ecrg4b
esophageal cancer related gene 4b
chr9_-_14137295 0.53 ENSDART00000127640
ENSDART00000189018
ENSDART00000188985
ttll4
tubulin tyrosine ligase-like family, member 4
chr1_-_43727012 0.52 ENSDART00000181064
bdh2
3-hydroxybutyrate dehydrogenase, type 2
chr6_+_41452979 0.52 ENSDART00000007353
wdr82
WD repeat domain 82
chr4_-_12930086 0.51 ENSDART00000013604
lemd3
LEM domain containing 3
chr3_-_40162843 0.51 ENSDART00000129664
ENSDART00000025285
drg2
developmentally regulated GTP binding protein 2
chr10_-_17587832 0.51 ENSDART00000113101
smarcad1b
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 b
chr7_+_15871408 0.51 ENSDART00000014572
pax6b
paired box 6b
chr1_+_33647682 0.50 ENSDART00000114384
znf654
zinc finger protein 654
chr7_+_67429185 0.50 ENSDART00000162553
ENSDART00000178646
kars
lysyl-tRNA synthetase
chr13_-_42536642 0.50 ENSDART00000134533
btaf1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated
chr18_-_12295092 0.50 ENSDART00000033248
fam107b
family with sequence similarity 107, member B
chr23_-_16734009 0.49 ENSDART00000125449
si:ch211-224l10.4
si:ch211-224l10.4
chr13_-_48388726 0.49 ENSDART00000169473
fbxo11a
F-box protein 11a
chr2_-_10821053 0.49 ENSDART00000056034
rpap2
RNA polymerase II associated protein 2
chr4_+_15899668 0.49 ENSDART00000101592
col7a1l
collagen type VII alpha 1-like
chr14_+_11457500 0.48 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr11_+_2172335 0.48 ENSDART00000170593
hoxc12b
homeobox C12b
chr5_-_42083363 0.48 ENSDART00000162596
cxcl11.5
chemokine (C-X-C motif) ligand 11, duplicate 5
chr16_-_36979592 0.47 ENSDART00000168443
snrnp48
small nuclear ribonucleoprotein 48 (U11/U12)
chr6_+_16406723 0.47 ENSDART00000040035
ccdc80l1
coiled-coil domain containing 80 like 1
chr12_-_7253270 0.46 ENSDART00000035762
ube2d1b
ubiquitin-conjugating enzyme E2D 1b
chr2_+_27010439 0.46 ENSDART00000030547
cdh7a
cadherin 7a
chr9_+_41459759 0.46 ENSDART00000132501
ENSDART00000100265
nemp2
nuclear envelope integral membrane protein 2
chr1_-_35924495 0.45 ENSDART00000184424
smad1
SMAD family member 1
chr8_-_53926228 0.45 ENSDART00000015554
ubiad1
UbiA prenyltransferase domain containing 1
chr15_-_24588649 0.45 ENSDART00000060469
gemin4
gem (nuclear organelle) associated protein 4
chr11_+_24316110 0.45 ENSDART00000186028
rem1
RAS (RAD and GEM)-like GTP-binding 1
chr9_+_3283608 0.45 ENSDART00000192275
hat1
histone acetyltransferase 1
chr5_-_56948058 0.45 ENSDART00000083074
ENSDART00000191028
si:ch211-127d4.3
si:ch211-127d4.3
chr17_-_33716688 0.44 ENSDART00000043651
dnal1
dynein, axonemal, light chain 1
chr25_+_7532627 0.44 ENSDART00000187660
ptdss2
phosphatidylserine synthase 2
chr22_+_16308806 0.44 ENSDART00000162685
lrrc39
leucine rich repeat containing 39
chr11_+_30647545 0.44 ENSDART00000114792
gb:eh507706
expressed sequence EH507706
chr6_-_40581376 0.44 ENSDART00000185412
tspo
translocator protein
chr12_+_11356592 0.44 ENSDART00000148770
si:rp71-19m20.1
si:rp71-19m20.1
chr17_-_36529016 0.44 ENSDART00000025019
colec11
collectin sub-family member 11
chr9_-_27720612 0.43 ENSDART00000000566
gtf2e1
general transcription factor IIE, polypeptide 1, alpha
chr16_+_9400661 0.43 ENSDART00000146174
ice1
KIAA0947-like (H. sapiens)
chr13_+_48359573 0.43 ENSDART00000161959
ENSDART00000165311
msh6
mutS homolog 6 (E. coli)
chr13_-_36391496 0.43 ENSDART00000100217
ENSDART00000140243
actn1
actinin, alpha 1
chr21_-_21178410 0.42 ENSDART00000185277
ENSDART00000141341
ENSDART00000145872
ENSDART00000079678
ftsj1
FtsJ RNA methyltransferase homolog 1
chr7_-_34192834 0.42 ENSDART00000125131
smad6a
SMAD family member 6a
chr2_+_1881334 0.42 ENSDART00000161420
adgrl2b.1
adhesion G protein-coupled receptor L2b, tandem duplicate 1
chr8_+_18830759 0.41 ENSDART00000089079
mpnd
MPN domain containing
chr4_+_17539134 0.41 ENSDART00000013313
itfg2
integrin alpha FG-GAP repeat containing 2
chr3_-_18737126 0.41 ENSDART00000055767
e4f1
E4F transcription factor 1
chr25_+_36348401 0.41 ENSDART00000103006
hist1h2a3
histone cluster 1 H2A family member 3
chr20_-_5400395 0.40 ENSDART00000168103
snw1
SNW domain containing 1
chr20_-_38787341 0.40 ENSDART00000136771
dnajc5ga
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a
chr12_+_27034594 0.40 ENSDART00000111679
fbrs
fibrosin
chr20_+_18703951 0.40 ENSDART00000191070
eif5
eukaryotic translation initiation factor 5
chr12_+_26706745 0.40 ENSDART00000141401
arhgap12b
Rho GTPase activating protein 12b
chr23_+_20431140 0.40 ENSDART00000193950
slc35c2
solute carrier family 35 (GDP-fucose transporter), member C2
chr25_-_27541621 0.40 ENSDART00000130678
spam1
sperm adhesion molecule 1
chr13_-_9159852 0.40 ENSDART00000170185
ENSDART00000158697
ENSDART00000143393
ENSDART00000164973
ENSDART00000159910
HTRA2 (1 of many)
si:dkey-112g5.16
chr22_-_9934011 0.39 ENSDART00000168223
si:dkey-253d23.9
si:dkey-253d23.9
chr22_-_20309283 0.39 ENSDART00000182125
ENSDART00000048775
si:dkey-110c1.10
si:dkey-110c1.10
chr23_+_20431388 0.39 ENSDART00000132920
ENSDART00000102963
ENSDART00000109899
ENSDART00000140219
slc35c2
solute carrier family 35 (GDP-fucose transporter), member C2
chr6_-_31682135 0.39 ENSDART00000153988
cachd1
cache domain containing 1
chr20_+_39686193 0.38 ENSDART00000153142
hddc2
HD domain containing 2
chr1_+_30946231 0.38 ENSDART00000022841
metap1d
methionyl aminopeptidase type 1D (mitochondrial)
chr3_+_13860815 0.37 ENSDART00000162451
ilf3b
interleukin enhancer binding factor 3b
chr17_+_21760032 0.37 ENSDART00000190425
ikzf5
IKAROS family zinc finger 5
chr10_-_2943474 0.37 ENSDART00000188698
oclna
occludin a
chr20_+_29209926 0.37 ENSDART00000152949
ENSDART00000153016
katnbl1
katanin p80 subunit B-like 1
chr16_-_29194517 0.37 ENSDART00000046114
ENSDART00000148899
mef2d
myocyte enhancer factor 2d
chr13_-_36582341 0.36 ENSDART00000137335
lgals3a
lectin, galactoside binding soluble 3a
chr3_+_24062748 0.36 ENSDART00000188574
cbx1a
chromobox homolog 1a (HP1 beta homolog Drosophila)
chr23_+_26142807 0.36 ENSDART00000158878
ptpn22
protein tyrosine phosphatase, non-receptor type 22
chr4_+_59711338 0.35 ENSDART00000150849
si:dkey-149m13.4
si:dkey-149m13.4
chr12_-_3299149 0.35 ENSDART00000182032
lsm12b
LSM12 homolog b
chr14_+_1240419 0.35 ENSDART00000181248
adad1
adenosine deaminase domain containing 1 (testis-specific)
chr24_-_32665283 0.35 ENSDART00000038364
ca2
carbonic anhydrase II
chr18_-_50839033 0.35 ENSDART00000169773
ddb1
damage-specific DNA binding protein 1
chr6_+_36844127 0.35 ENSDART00000020505
chd1l
chromodomain helicase DNA binding protein 1-like
chr8_-_51367298 0.35 ENSDART00000060628
chmp7
charged multivesicular body protein 7
chr12_+_28910762 0.35 ENSDART00000076342
ENSDART00000160939
ENSDART00000076572
rnf40
ring finger protein 40
chr21_-_7781555 0.35 ENSDART00000084380
ENSDART00000189131
aggf1
angiogenic factor with G patch and FHA domains 1
chr5_-_64203101 0.34 ENSDART00000029364
ak5l
adenylate kinase 5, like
chr3_-_21062706 0.34 ENSDART00000155605
ENSDART00000153686
ENSDART00000157168
ENSDART00000156614
ENSDART00000155743
ENSDART00000156275
fam57ba
family with sequence similarity 57, member Ba
chr25_+_19489370 0.34 ENSDART00000091132
glsl
glutaminase like
chr2_-_7189594 0.34 ENSDART00000139703
rc3h1b
ring finger and CCCH-type domains 1b
chr14_-_31693148 0.34 ENSDART00000172958
map7d3
MAP7 domain containing 3
chr23_+_36653376 0.34 ENSDART00000053189
gpr182
G protein-coupled receptor 182
chr5_+_59449762 0.33 ENSDART00000150230
clip2
CAP-GLY domain containing linker protein 2
chr24_-_1023112 0.33 ENSDART00000147508
ENSDART00000066863
ralaa
v-ral simian leukemia viral oncogene homolog Aa (ras related)
chr4_+_29909870 0.33 ENSDART00000150324
znf1111
zinc finger protein 1111
chr7_-_38664947 0.32 ENSDART00000100546
ENSDART00000112405
c6ast1
six-cysteine containing astacin protease 1
chr4_+_52356485 0.32 ENSDART00000170639
zgc:173705
zgc:173705
chr9_-_41025062 0.32 ENSDART00000002053
pms1
PMS1 homolog 1, mismatch repair system component
chr21_+_31253048 0.32 ENSDART00000178521
ENSDART00000132317
ENSDART00000040190
asl
argininosuccinate lyase
chr7_+_8543317 0.31 ENSDART00000114998
jac8
jacalin 8
chr21_-_30408775 0.31 ENSDART00000101037
nhp2
NHP2 ribonucleoprotein homolog (yeast)
chr20_-_38787047 0.31 ENSDART00000152913
ENSDART00000153430
dnajc5ga
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a
chr18_+_35861930 0.30 ENSDART00000185223
ppp1r13l
protein phosphatase 1, regulatory subunit 13 like
chr11_-_16395956 0.30 ENSDART00000115085
lrig1
leucine-rich repeats and immunoglobulin-like domains 1

Network of associatons between targets according to the STRING database.

First level regulatory network of isl1+isl1l

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:0032790 ribosome disassembly(GO:0032790)
0.6 2.2 GO:0051444 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.3 1.3 GO:0061549 sympathetic ganglion development(GO:0061549)
0.3 0.8 GO:1903334 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.3 0.8 GO:0070417 cellular response to cold(GO:0070417)
0.2 1.0 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.2 1.0 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.2 1.1 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.2 2.4 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.2 1.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.2 0.6 GO:0090008 hypoblast development(GO:0090008)
0.2 0.2 GO:0035773 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.2 1.1 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 0.5 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.2 0.5 GO:0070314 G1 to G0 transition(GO:0070314)
0.2 0.5 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.2 0.9 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.2 1.0 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.2 0.8 GO:0000741 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.2 0.5 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2 1.1 GO:0003311 pancreatic D cell differentiation(GO:0003311) pancreatic epsilon cell differentiation(GO:0090104)
0.2 0.5 GO:0042373 vitamin K metabolic process(GO:0042373) cellular response to fluid shear stress(GO:0071498)
0.1 0.4 GO:0001112 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.1 0.4 GO:0006290 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.9 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.1 0.9 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.8 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.1 1.8 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.1 0.8 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.1 0.7 GO:0055014 outflow tract morphogenesis(GO:0003151) atrial cardiac muscle cell development(GO:0055014)
0.1 1.2 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.1 1.2 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.5 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.1 0.3 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 1.2 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 1.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.4 GO:0070084 protein initiator methionine removal(GO:0070084)
0.1 0.6 GO:0001955 blood vessel maturation(GO:0001955)
0.1 0.4 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.9 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 0.3 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 1.3 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.1 0.7 GO:0021871 forebrain regionalization(GO:0021871)
0.1 1.2 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 0.3 GO:0006591 arginine biosynthetic process(GO:0006526) ornithine metabolic process(GO:0006591)
0.1 0.5 GO:0035475 angioblast cell migration involved in selective angioblast sprouting(GO:0035475)
0.1 0.4 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.9 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 0.3 GO:0019884 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 1.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.4 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.1 0.7 GO:0030656 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.1 0.8 GO:0021754 facial nucleus development(GO:0021754)
0.1 0.4 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.5 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 0.7 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.4 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.4 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.2 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.4 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.5 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.5 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.3 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.6 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0003232 bulbus arteriosus development(GO:0003232)
0.0 0.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.4 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.6 GO:0014823 response to activity(GO:0014823)
0.0 0.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.3 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:0044821 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.4 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0050999 regulation of nitric-oxide synthase activity(GO:0050999) positive regulation of nitric-oxide synthase activity(GO:0051000) beta-amyloid clearance(GO:0097242) regulation of beta-amyloid clearance(GO:1900221)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026) peptidyl-lysine dimethylation(GO:0018027)
0.0 0.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.7 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.6 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0030262 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.2 GO:0035094 response to nicotine(GO:0035094)
0.0 0.1 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.5 GO:0060034 notochord cell differentiation(GO:0060034)
0.0 0.2 GO:2000047 regulation of cell-cell adhesion mediated by cadherin(GO:2000047)
0.0 0.1 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.6 GO:0001878 response to yeast(GO:0001878)
0.0 0.4 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.4 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.3 GO:0006298 mismatch repair(GO:0006298)
0.0 0.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.5 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.2 GO:0001881 receptor recycling(GO:0001881)
0.0 0.5 GO:0071219 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.0 0.4 GO:0014029 neural crest formation(GO:0014029)
0.0 0.7 GO:0048484 enteric nervous system development(GO:0048484)
0.0 1.2 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.1 GO:0042766 nucleosome mobilization(GO:0042766)
0.0 0.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.9 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.2 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0072380 TRC complex(GO:0072380)
0.2 1.0 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.2 1.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.2 0.6 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.1 0.4 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.8 GO:0031262 Ndc80 complex(GO:0031262)
0.1 1.0 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.4 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.3 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.7 GO:0032021 NELF complex(GO:0032021)
0.1 0.9 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.4 GO:0031430 M band(GO:0031430)
0.1 0.2 GO:0016600 flotillin complex(GO:0016600)
0.1 0.5 GO:0032797 SMN complex(GO:0032797)
0.1 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.8 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.6 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.2 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 1.1 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 1.2 GO:0005657 replication fork(GO:0005657)
0.0 0.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.4 GO:0030286 dynein complex(GO:0030286)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.0 GO:0000776 kinetochore(GO:0000776)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 1.7 GO:0005581 collagen trimer(GO:0005581)
0.0 1.2 GO:0005814 centriole(GO:0005814)
0.0 1.1 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.8 GO:0031965 nuclear membrane(GO:0031965)
0.0 2.9 GO:0005819 spindle(GO:0005819)
0.0 0.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 0.0 GO:0044279 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.3 1.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 1.0 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.2 1.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.2 0.7 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.2 1.0 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.2 1.2 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.4 GO:0042806 fucose binding(GO:0042806)
0.1 0.4 GO:0032405 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.1 0.5 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.1 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 1.7 GO:0070122 isopeptidase activity(GO:0070122)
0.1 0.2 GO:0034246 core DNA-dependent RNA polymerase binding promoter specificity activity(GO:0000996) mitochondrial RNA polymerase binding promoter specificity activity(GO:0034246)
0.1 0.4 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.4 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 0.6 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 1.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.5 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 1.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.9 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 0.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.6 GO:0070697 activin receptor binding(GO:0070697)
0.0 0.4 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.9 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.6 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.5 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.4 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 1.0 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.8 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.5 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.0 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 1.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 2.4 GO:0004519 endonuclease activity(GO:0004519)
0.0 1.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 2.2 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.0 0.4 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.9 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0016405 CoA-ligase activity(GO:0016405)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 2.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.0 2.0 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.2 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.6 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 3.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.6 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.0 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.9 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.5 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME KINESINS Genes involved in Kinesins
0.0 0.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.5 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis