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PRJEB1986: zebrafish developmental stages transcriptome

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Results for klf12a

Z-value: 1.51

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Transcription factors associated with klf12a

Gene Symbol Gene ID Gene Info
klf12a
ENSDARG00000015312 Kruppel-like factor 12a
klf12a
ENSDARG00000115152 Kruppel-like factor 12a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
klf12adr11_v1_chr1_+_34527213_345272130.455.1e-02Click!

Activity profile of klf12a motif

Sorted Z-values of klf12a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr24_+_42132962 4.00 ENSDART00000187739
wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr3_+_1211242 3.98 ENSDART00000171287
ENSDART00000165769
poldip3
polymerase (DNA-directed), delta interacting protein 3
chr16_-_17197546 3.70 ENSDART00000139939
ENSDART00000135146
ENSDART00000063800
ENSDART00000163606
gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr17_+_8925232 3.15 ENSDART00000036668
psmc1a
proteasome 26S subunit, ATPase 1a
chr13_+_28417297 3.02 ENSDART00000043658
slc2a15a
solute carrier family 2 (facilitated glucose transporter), member 15a
chr4_+_17417111 2.88 ENSDART00000056005
ascl1a
achaete-scute family bHLH transcription factor 1a
chr25_+_3358701 2.82 ENSDART00000104877
chchd3b
coiled-coil-helix-coiled-coil-helix domain containing 3b
chr20_+_35058634 2.69 ENSDART00000122696
hnrnpub
heterogeneous nuclear ribonucleoprotein Ub
chr7_-_48665305 2.65 ENSDART00000190507
cdkn1ca
cyclin-dependent kinase inhibitor 1Ca
chr17_+_25332711 2.51 ENSDART00000082319
tmem54a
transmembrane protein 54a
chr17_-_14815557 2.47 ENSDART00000154473
nid2a
nidogen 2a (osteonidogen)
chr13_-_33671694 2.42 ENSDART00000143945
ENSDART00000100504
zgc:163030
zgc:163030
chr24_+_42127983 2.39 ENSDART00000190157
ENSDART00000176032
ENSDART00000175790
wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr18_-_14677936 2.36 ENSDART00000111995
si:dkey-238o13.4
si:dkey-238o13.4
chr2_+_59015878 2.31 ENSDART00000148816
ENSDART00000122795
si:ch1073-391i24.1
si:ch1073-391i24.1
chr5_+_66132394 2.28 ENSDART00000073892
zgc:114041
zgc:114041
chr3_-_50998577 2.20 ENSDART00000157735
cdc42ep4a
CDC42 effector protein (Rho GTPase binding) 4a
chr3_-_32541033 2.19 ENSDART00000151476
ENSDART00000055324
rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr21_-_308852 2.13 ENSDART00000151613
lhfpl2a
LHFPL tetraspan subfamily member 2a
chr2_-_39675829 2.12 ENSDART00000147821
spsb4a
splA/ryanodine receptor domain and SOCS box containing 4a
chr4_-_9852318 2.11 ENSDART00000080702
glt8d2
glycosyltransferase 8 domain containing 2
chr18_-_49318823 2.10 ENSDART00000098419
sb:cb81
sb:cb81
chr23_-_3759692 2.05 ENSDART00000028885
hmga1a
high mobility group AT-hook 1a
chr1_-_59232267 2.04 ENSDART00000169658
ENSDART00000163257
akap8l
A kinase (PRKA) anchor protein 8-like
chr3_+_27027781 2.02 ENSDART00000065495
emp2
epithelial membrane protein 2
chr22_-_12626105 2.01 ENSDART00000115344
ENSDART00000193390
ENSDART00000183949
cep70
centrosomal protein 70
chr23_-_31645760 1.97 ENSDART00000035031
sgk1
serum/glucocorticoid regulated kinase 1
chr22_+_5118361 1.95 ENSDART00000168371
ENSDART00000170222
ENSDART00000158846
mibp
muscle-specific beta 1 integrin binding protein
chr7_+_38349667 1.95 ENSDART00000010046
rhpn2
rhophilin, Rho GTPase binding protein 2
chr14_+_33264303 1.89 ENSDART00000130680
ENSDART00000075187
pdzd11
PDZ domain containing 11
chr9_-_1984604 1.85 ENSDART00000082339
hoxd12a
homeobox D12a
chr22_-_2922053 1.80 ENSDART00000178290
pak2b
p21 protein (Cdc42/Rac)-activated kinase 2b
chr11_-_25384213 1.77 ENSDART00000103650
mafbb
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Bb
chr12_+_11080776 1.73 ENSDART00000079336
raraa
retinoic acid receptor, alpha a
chr7_-_18601206 1.72 ENSDART00000111636
DTX4
si:ch211-119e14.2
chr13_+_4405282 1.69 ENSDART00000148280
prr18
proline rich 18
chr13_-_36621926 1.67 ENSDART00000057155
cdkn3
cyclin-dependent kinase inhibitor 3
chr10_+_15777064 1.66 ENSDART00000114483
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr22_-_775776 1.65 ENSDART00000149749
rbbp5
retinoblastoma binding protein 5
chr8_-_4618653 1.64 ENSDART00000025535
sept5a
septin 5a
chr22_-_21676364 1.64 ENSDART00000183668
tle2b
transducin like enhancer of split 2b
chr2_-_27900518 1.64 ENSDART00000109561
ENSDART00000077720
zgc:163121
zgc:163121
chr22_+_835728 1.62 ENSDART00000003325
dennd2db
DENN/MADD domain containing 2Db
chr25_+_3306858 1.60 ENSDART00000137077
slc25a3b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b
chr13_-_6252498 1.60 ENSDART00000115157
tuba4l
tubulin, alpha 4 like
chr19_+_47394270 1.60 ENSDART00000171281
psmb2
proteasome subunit beta 2
chr23_-_3759345 1.59 ENSDART00000132205
ENSDART00000137707
ENSDART00000189382
hmga1a
high mobility group AT-hook 1a
chr1_-_54107321 1.58 ENSDART00000148382
ENSDART00000150357
rfx1b
regulatory factor X, 1b (influences HLA class II expression)
chr24_+_17005647 1.53 ENSDART00000149149
zfx
zinc finger protein, X-linked
chr5_+_23136544 1.52 ENSDART00000003428
ENSDART00000109340
ENSDART00000171039
ENSDART00000178821
prps1a
phosphoribosyl pyrophosphate synthetase 1A
chr23_+_30730121 1.48 ENSDART00000134141
asxl1
additional sex combs like transcriptional regulator 1
chr8_+_17167876 1.48 ENSDART00000134665
cenph
centromere protein H
chr19_+_29854223 1.45 ENSDART00000109729
ENSDART00000157419
si:ch73-130a3.4
si:ch73-130a3.4
chr14_+_26439227 1.45 ENSDART00000054183
gpr137
G protein-coupled receptor 137
chr25_+_34013093 1.43 ENSDART00000011967
anxa2a
annexin A2a
chr6_+_16031189 1.42 ENSDART00000015333
gbx2
gastrulation brain homeobox 2
chr11_+_29790626 1.41 ENSDART00000067822
dynlt3
dynein, light chain, Tctex-type 3
chr22_-_18546241 1.39 ENSDART00000105404
ENSDART00000105405
cirbpb
cold inducible RNA binding protein b
chr14_+_24277556 1.38 ENSDART00000122660
hnrnpa0a
heterogeneous nuclear ribonucleoprotein A0a
chr18_+_41549764 1.38 ENSDART00000059135
bcl7bb
BCL tumor suppressor 7Bb
chr21_+_30549512 1.38 ENSDART00000132831
rab38c
RAB38c, member of RAS oncogene family
chr14_+_97017 1.38 ENSDART00000159300
ENSDART00000169523
mcm7
minichromosome maintenance complex component 7
chr22_-_881080 1.37 ENSDART00000185489
cept1b
choline/ethanolamine phosphotransferase 1b
chr9_+_34425736 1.36 ENSDART00000135147
si:ch211-218d20.15
si:ch211-218d20.15
chr23_-_6749820 1.35 ENSDART00000128772
ptges3b
prostaglandin E synthase 3b (cytosolic)
chr12_+_42436328 1.34 ENSDART00000167324
ebf3a
early B cell factor 3a
chr13_+_16279890 1.34 ENSDART00000101775
ENSDART00000057948
anxa11a
annexin A11a
chr18_-_46258612 1.33 ENSDART00000153930
si:dkey-244a7.1
si:dkey-244a7.1
chr8_+_20157798 1.32 ENSDART00000124809
acsbg2
acyl-CoA synthetase bubblegum family member 2
chr3_+_23692462 1.30 ENSDART00000145934
hoxb7a
homeobox B7a
chr19_-_30420602 1.30 ENSDART00000144121
ppp1r10
protein phosphatase 1, regulatory subunit 10
chr12_+_48815988 1.29 ENSDART00000149089
anxa11b
annexin A11b
chr23_-_19831739 1.29 ENSDART00000125066
haus7
HAUS augmin-like complex, subunit 7
chr7_+_10563017 1.29 ENSDART00000193520
ENSDART00000173125
zfand6
zinc finger, AN1-type domain 6
chr17_-_114121 1.28 ENSDART00000172408
ENSDART00000157784
arhgap11a
Rho GTPase activating protein 11A
chr23_-_27822920 1.28 ENSDART00000023094
acvr1ba
activin A receptor type 1Ba
chr18_+_44649804 1.27 ENSDART00000059063
ehd2b
EH-domain containing 2b
chr7_-_59159253 1.26 ENSDART00000159285
haus6
HAUS augmin-like complex, subunit 6
chr2_-_32513538 1.26 ENSDART00000056640
abcf2a
ATP-binding cassette, sub-family F (GCN20), member 2a
chr19_-_42391383 1.26 ENSDART00000110075
ENSDART00000087002
plekho1a
pleckstrin homology domain containing, family O member 1a
chr25_+_3306620 1.25 ENSDART00000182085
ENSDART00000034704
slc25a3b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b
chr24_-_21923930 1.25 ENSDART00000131944
tagln3b
transgelin 3b
chr19_+_46237665 1.24 ENSDART00000159391
vps28
vacuolar protein sorting 28 (yeast)
chr17_-_14816465 1.23 ENSDART00000156326
ENSDART00000156287
nid2a
nidogen 2a (osteonidogen)
chr13_+_421231 1.22 ENSDART00000188212
ENSDART00000017854
lgi1a
leucine-rich, glioma inactivated 1a
chr14_-_6225336 1.21 ENSDART00000111681
hdx
highly divergent homeobox
chr8_+_17168114 1.21 ENSDART00000183901
cenph
centromere protein H
chr21_-_13856689 1.21 ENSDART00000102197
fam129ba
family with sequence similarity 129, member Ba
chr3_+_15893039 1.19 ENSDART00000055780
jpt2
Jupiter microtubule associated homolog 2
chr16_-_21777545 1.19 ENSDART00000039381
cops7a
COP9 constitutive photomorphogenic homolog subunit 7A
chr13_+_18471546 1.18 ENSDART00000090712
ENSDART00000127962
stox1
storkhead box 1
chr3_-_40528333 1.17 ENSDART00000193047
actb2
actin, beta 2
chr17_+_16429826 1.17 ENSDART00000136078
efcab11
EF-hand calcium binding domain 11
chr22_-_4887401 1.16 ENSDART00000190841
si:ch73-256j6.4
si:ch73-256j6.4
chr25_+_186583 1.15 ENSDART00000161504
pclaf
PCNA clamp associated factor
chr5_-_9824908 1.13 ENSDART00000169698
zgc:158343
zgc:158343
chr15_-_5580093 1.13 ENSDART00000143726
wdr62
WD repeat domain 62
chr20_-_25748407 1.12 ENSDART00000063152
chst14
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr5_-_36597612 1.11 ENSDART00000031270
ENSDART00000122098
rhogc
ras homolog gene family, member Gc
chr15_+_47161917 1.11 ENSDART00000167860
gap43
growth associated protein 43
chr25_+_19008497 1.11 ENSDART00000104420
samm50
SAMM50 sorting and assembly machinery component
chr16_-_45327616 1.11 ENSDART00000158733
si:dkey-33i11.1
si:dkey-33i11.1
chr12_-_49168398 1.10 ENSDART00000186608
FO704624.1

chr24_-_35534273 1.09 ENSDART00000026578
ube2v2
ubiquitin-conjugating enzyme E2 variant 2
chr20_+_29565906 1.09 ENSDART00000062383
ywhaqa
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a
chr4_-_11810365 1.08 ENSDART00000150529
cyb5r3
cytochrome b5 reductase 3
chr10_+_8629275 1.08 ENSDART00000129643
aplnrb
apelin receptor b
chr16_+_28764017 1.08 ENSDART00000122433
trim33l
tripartite motif containing 33, like
chr17_+_44441042 1.07 ENSDART00000142123
ap5m1
adaptor-related protein complex 5, mu 1 subunit
chr5_+_26913120 1.06 ENSDART00000126609
tbx3b
T-box 3b
chr24_-_4450238 1.05 ENSDART00000066835
fzd8a
frizzled class receptor 8a
chr18_-_3166726 1.04 ENSDART00000165002
aqp11
aquaporin 11
chr15_+_17752928 1.04 ENSDART00000155314
si:ch211-213d14.2
si:ch211-213d14.2
chr12_-_48312647 1.03 ENSDART00000114415
ascc1
activating signal cointegrator 1 complex subunit 1
chr8_-_14179798 1.03 ENSDART00000040645
ENSDART00000146749
rhoaa
ras homolog gene family, member Aa
chr7_+_9880811 1.03 ENSDART00000128376
lins1
lines homolog 1
chr6_-_18976168 1.03 ENSDART00000170039
sept9b
septin 9b
chr2_+_30379650 1.01 ENSDART00000129542
crispld1b
cysteine-rich secretory protein LCCL domain containing 1b
chr17_-_24889837 1.01 ENSDART00000187980
gale
UDP-galactose-4-epimerase
chr5_-_72136548 1.00 ENSDART00000007827
spra
sepiapterin reductase a
chr16_+_26747766 1.00 ENSDART00000183257
rad54b
RAD54 homolog B (S. cerevisiae)
chr10_+_15777258 1.00 ENSDART00000140511
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr11_-_36279602 1.00 ENSDART00000122531
ENSDART00000103064
ENSDART00000125616
nfya
nuclear transcription factor Y, alpha
chr1_-_59313465 0.99 ENSDART00000158067
ENSDART00000159419
txndc11
thioredoxin domain containing 11
chr15_-_20468302 0.98 ENSDART00000018514
dlc
deltaC
chr17_-_18898115 0.98 ENSDART00000028044
galcb
galactosylceramidase b
chr1_+_42874410 0.97 ENSDART00000153506
ctnna2
catenin (cadherin-associated protein), alpha 2
chr22_+_661711 0.97 ENSDART00000113795
elf3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr19_-_34011340 0.97 ENSDART00000172618
elmo1
engulfment and cell motility 1 (ced-12 homolog, C. elegans)
chr4_+_9011448 0.97 ENSDART00000192357
samm50l
sorting and assembly machinery component 50 homolog, like
chr19_-_35450661 0.96 ENSDART00000113574
ENSDART00000136895
anln
anillin, actin binding protein
chr7_-_20796935 0.96 ENSDART00000162357
dnajc3b
DnaJ (Hsp40) homolog, subfamily C, member 3b
chr6_-_25165693 0.95 ENSDART00000167259
znf326
zinc finger protein 326
chr9_+_3035128 0.95 ENSDART00000140693
si:ch211-173m16.2
si:ch211-173m16.2
chr3_+_32410746 0.95 ENSDART00000025496
rras
RAS related
chr17_-_20229812 0.94 ENSDART00000155989
ebf3b
early B cell factor 3b
chr6_+_12968101 0.94 ENSDART00000013781
mcm6
minichromosome maintenance complex component 6
chr19_-_31372896 0.94 ENSDART00000046609
scin
scinderin
chr23_+_44080382 0.93 ENSDART00000011715
zgc:56304
zgc:56304
chr2_+_43894368 0.92 ENSDART00000143885
gbp3
guanylate binding protein 3
chr14_+_80685 0.92 ENSDART00000188443
stag3
stromal antigen 3
chr22_+_344763 0.92 ENSDART00000181934
CU914780.1

chr4_-_4612116 0.92 ENSDART00000130601
CABZ01020840.1
Danio rerio apoptosis facilitator Bcl-2-like protein 14 (LOC101885512), mRNA.
chr17_-_31695217 0.91 ENSDART00000104332
ENSDART00000143090
lin52
lin-52 DREAM MuvB core complex component
chr5_+_36850650 0.90 ENSDART00000051186
nccrp1
non-specific cytotoxic cell receptor protein 1
chr3_-_32362872 0.90 ENSDART00000035545
ENSDART00000012630
prmt1
protein arginine methyltransferase 1
chr20_+_20672163 0.90 ENSDART00000027758
rtn1b
reticulon 1b
chr12_+_499881 0.90 ENSDART00000167527
mprip
myosin phosphatase Rho interacting protein
chr6_-_57938043 0.89 ENSDART00000171073
tox2
TOX high mobility group box family member 2
chr4_-_11810799 0.89 ENSDART00000014153
cyb5r3
cytochrome b5 reductase 3
chr3_-_31924643 0.87 ENSDART00000122589
rnf113a
ring finger protein 113A
chr14_+_28545198 0.87 ENSDART00000125362
ENSDART00000105902
hmmr
hyaluronan-mediated motility receptor (RHAMM)
chr5_+_68807170 0.86 ENSDART00000017849
her7
hairy and enhancer of split related-7
chr23_-_37085959 0.85 ENSDART00000139662
ENSDART00000031016
ints11
integrator complex subunit 11
chr21_-_32060993 0.85 ENSDART00000131651
si:ch211-160j14.2
si:ch211-160j14.2
chr2_-_37837056 0.85 ENSDART00000158179
ENSDART00000160317
ENSDART00000171409
mettl17
methyltransferase like 17
chr6_-_40657653 0.84 ENSDART00000154359
ppil1
peptidylprolyl isomerase (cyclophilin)-like 1
chr11_-_36341028 0.84 ENSDART00000146093
sort1a
sortilin 1a
chr23_+_10146542 0.83 ENSDART00000048073
zgc:171775
zgc:171775
chr21_+_25236297 0.83 ENSDART00000112783
tmem45b
transmembrane protein 45B
chr22_+_396840 0.83 ENSDART00000163198
capzb
capping protein (actin filament) muscle Z-line, beta
chr20_+_812012 0.82 ENSDART00000179299
ENSDART00000137135
mei4
meiosis-specific, MEI4 homolog (S. cerevisiae)
chr15_+_28410664 0.82 ENSDART00000132028
ENSDART00000057697
ENSDART00000057257
pitpnaa
phosphatidylinositol transfer protein, alpha a
chr2_+_23222939 0.81 ENSDART00000026800
kifap3b
kinesin-associated protein 3b
chr12_+_6391243 0.80 ENSDART00000152765
prkg1b
protein kinase, cGMP-dependent, type Ib
chr9_+_23895711 0.80 ENSDART00000034686
cops8
COP9 signalosome subunit 8
chr14_-_46442459 0.79 ENSDART00000158770
fgfbp1b
fibroblast growth factor binding protein 1b
chr1_+_45922699 0.79 ENSDART00000033669
lipt1
lipoyltransferase 1
chr21_-_41369370 0.79 ENSDART00000159290
cpeb4b
cytoplasmic polyadenylation element binding protein 4b
chr5_-_64431927 0.79 ENSDART00000158248
brd3b
bromodomain containing 3b
chr14_-_24277805 0.79 ENSDART00000054243
dpf2l
D4, zinc and double PHD fingers family 2, like
chr8_-_32385989 0.78 ENSDART00000143716
ENSDART00000098850
lipg
lipase, endothelial
chr6_+_18520859 0.78 ENSDART00000158263
si:dkey-10p5.10
si:dkey-10p5.10
chr20_-_46554440 0.77 ENSDART00000043298
ENSDART00000060680
fosab
v-fos FBJ murine osteosarcoma viral oncogene homolog Ab
chr7_+_23907692 0.77 ENSDART00000045479
syt4
synaptotagmin IV
chr3_+_22984098 0.77 ENSDART00000043190
lsm12a
LSM12 homolog a
chr2_+_25658112 0.76 ENSDART00000051234
tnika
TRAF2 and NCK interacting kinase a
chr7_+_40083601 0.76 ENSDART00000099046
zgc:112356
zgc:112356
chr19_+_27479838 0.76 ENSDART00000103922
atat1
alpha tubulin acetyltransferase 1
chr3_+_726000 0.76 ENSDART00000158510
dicp1.17
diverse immunoglobulin domain-containing protein 1.17
chr6_+_7533601 0.76 ENSDART00000057823
pa2g4a
proliferation-associated 2G4, a
chr21_+_6197223 0.75 ENSDART00000147716
si:dkey-93m18.3
si:dkey-93m18.3
chr1_-_54100988 0.75 ENSDART00000192662
rfx1b
regulatory factor X, 1b (influences HLA class II expression)
chr10_-_8294965 0.75 ENSDART00000167380
plpp1a
phospholipid phosphatase 1a
chr17_-_30944566 0.74 ENSDART00000192663
evla
Enah/Vasp-like a
chr22_+_1947494 0.74 ENSDART00000159121
si:dkey-15h8.15
si:dkey-15h8.15
chr14_-_1355544 0.74 ENSDART00000060417
cetn4
centrin 4
chr9_+_1654284 0.73 ENSDART00000062854
nfe2l2a
nuclear factor, erythroid 2-like 2a
chr20_+_13894123 0.73 ENSDART00000007744
slc30a1a
solute carrier family 30 (zinc transporter), member 1a
chr8_-_17167819 0.73 ENSDART00000135042
ENSDART00000143920
mrps36
mitochondrial ribosomal protein S36
chr4_+_16710001 0.72 ENSDART00000035899
pkp2
plakophilin 2
chr2_+_20967673 0.72 ENSDART00000057174
arpc5a
actin related protein 2/3 complex, subunit 5A
chr11_-_11301283 0.71 ENSDART00000113311
ENSDART00000180466
col9a1a
collagen, type IX, alpha 1a
chr7_-_48396193 0.71 ENSDART00000083555
sin3ab
SIN3 transcription regulator family member Ab
chr2_+_25657958 0.70 ENSDART00000161407
tnika
TRAF2 and NCK interacting kinase a
chr24_-_11076400 0.70 ENSDART00000003195
chmp4c
charged multivesicular body protein 4C
chr9_+_30421489 0.70 ENSDART00000145025
ENSDART00000132058
zgc:113314
zgc:113314
chr16_-_7793457 0.69 ENSDART00000113483
trim71
tripartite motif containing 71, E3 ubiquitin protein ligase
chr13_-_44808783 0.69 ENSDART00000099984
glo1
glyoxalase 1
chr7_-_31938938 0.68 ENSDART00000132353
bdnf
brain-derived neurotrophic factor

Network of associatons between targets according to the STRING database.

First level regulatory network of klf12a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.7 2.9 GO:0061549 sympathetic ganglion development(GO:0061549)
0.7 2.0 GO:0003093 renal system process involved in regulation of blood volume(GO:0001977) renal system process involved in regulation of systemic arterial blood pressure(GO:0003071) regulation of glomerular filtration(GO:0003093)
0.7 2.7 GO:1904357 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.7 2.0 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.4 1.5 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.4 2.6 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.4 1.9 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.4 1.1 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531) eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.3 1.1 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.2 0.7 GO:1990359 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.2 1.0 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.2 1.0 GO:0008356 asymmetric cell division(GO:0008356)
0.2 2.1 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.2 0.9 GO:0034969 histone arginine methylation(GO:0034969)
0.2 0.7 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.2 2.2 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.2 2.3 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 1.0 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.2 1.1 GO:0050655 dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.2 1.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 1.1 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.2 2.7 GO:0051382 kinetochore assembly(GO:0051382)
0.2 0.5 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.2 0.8 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.2 1.0 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 1.0 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.6 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 1.4 GO:0021871 forebrain regionalization(GO:0021871)
0.1 1.0 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.7 GO:0010586 miRNA metabolic process(GO:0010586)
0.1 1.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.6 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 1.9 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 1.3 GO:0001709 cell fate determination(GO:0001709)
0.1 1.0 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.7 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.1 1.4 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 1.6 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.1 2.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 1.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.8 GO:0009249 protein lipoylation(GO:0009249)
0.1 2.8 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.1 1.6 GO:0042559 pteridine-containing compound biosynthetic process(GO:0042559)
0.1 0.9 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.8 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.7 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.5 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 3.7 GO:0050821 protein stabilization(GO:0050821)
0.1 0.6 GO:0032447 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.1 2.6 GO:0032506 cytokinetic process(GO:0032506)
0.1 0.5 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 2.2 GO:0006301 postreplication repair(GO:0006301)
0.1 0.9 GO:0043144 snoRNA processing(GO:0043144)
0.1 1.4 GO:0009409 response to cold(GO:0009409)
0.1 3.7 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.9 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379) cellular response to fatty acid(GO:0071398)
0.1 0.4 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.1 0.6 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.4 GO:0070292 N-acylphosphatidylethanolamine metabolic process(GO:0070292)
0.1 0.6 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.1 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.5 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.3 GO:1990535 neuron projection maintenance(GO:1990535)
0.1 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.4 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.1 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.1 GO:0016198 axon choice point recognition(GO:0016198)
0.1 1.0 GO:0061055 myotome development(GO:0061055)
0.1 0.5 GO:0021634 optic nerve formation(GO:0021634)
0.1 1.4 GO:0032438 melanosome organization(GO:0032438)
0.1 1.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 1.5 GO:0072662 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1 6.4 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.1 1.8 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 1.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.6 GO:0033260 nuclear DNA replication(GO:0033260)
0.1 0.6 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 0.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 1.7 GO:0032526 response to retinoic acid(GO:0032526)
0.1 0.7 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 0.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 1.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 1.0 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.6 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.6 GO:0051963 regulation of synapse assembly(GO:0051963)
0.0 0.2 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.0 0.9 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.9 GO:0001757 somite specification(GO:0001757)
0.0 0.4 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 1.0 GO:0016180 snRNA processing(GO:0016180)
0.0 0.4 GO:0006108 malate metabolic process(GO:0006108)
0.0 2.7 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 2.6 GO:0051225 spindle assembly(GO:0051225)
0.0 0.7 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.8 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.2 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.0 0.6 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.9 GO:0051014 actin filament severing(GO:0051014)
0.0 1.3 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.3 GO:0061098 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of protein tyrosine kinase activity(GO:0061098) positive regulation of receptor activity(GO:2000273)
0.0 0.8 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.3 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.4 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 1.3 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.0 1.6 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.7 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.2 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.6 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.1 GO:0035143 caudal fin morphogenesis(GO:0035143)
0.0 1.1 GO:0003205 cardiac chamber development(GO:0003205)
0.0 3.5 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.5 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 0.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 2.0 GO:0032147 activation of protein kinase activity(GO:0032147)
0.0 0.3 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.6 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.7 GO:0043648 dicarboxylic acid metabolic process(GO:0043648)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 1.0 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 0.8 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.3 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.5 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.9 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.4 GO:0070831 basement membrane assembly(GO:0070831)
0.0 3.7 GO:0006954 inflammatory response(GO:0006954)
0.0 0.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 1.0 GO:0006476 protein deacetylation(GO:0006476)
0.0 0.4 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.2 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0 1.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 1.2 GO:0042552 myelination(GO:0042552)
0.0 1.4 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 0.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.5 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 0.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.2 GO:0008354 germ cell migration(GO:0008354)
0.0 0.6 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.4 1.5 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.3 2.6 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.3 1.6 GO:0097433 dense body(GO:0097433)
0.3 1.1 GO:0032584 growth cone membrane(GO:0032584)
0.3 2.8 GO:0061617 MICOS complex(GO:0061617)
0.2 0.7 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.2 1.0 GO:0044609 DBIRD complex(GO:0044609)
0.2 3.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.2 1.5 GO:0035517 PR-DUB complex(GO:0035517)
0.2 1.3 GO:0070652 HAUS complex(GO:0070652)
0.2 2.0 GO:0008180 COP9 signalosome(GO:0008180)
0.2 0.8 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 1.0 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 2.3 GO:0042555 MCM complex(GO:0042555)
0.1 1.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.6 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.5 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.5 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.1 1.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 1.3 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.2 GO:0000813 ESCRT I complex(GO:0000813)
0.1 2.7 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 0.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.9 GO:0002102 podosome(GO:0002102)
0.1 2.9 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.5 GO:0001772 immunological synapse(GO:0001772)
0.1 0.7 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.6 GO:0005839 proteasome core complex(GO:0005839)
0.1 5.4 GO:0005604 basement membrane(GO:0005604)
0.1 0.7 GO:0014704 intercalated disc(GO:0014704)
0.1 0.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.7 GO:0000815 ESCRT III complex(GO:0000815)
0.0 4.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.8 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.9 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.0 0.5 GO:0030904 retromer complex(GO:0030904)
0.0 2.7 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.9 GO:0008278 cohesin complex(GO:0008278)
0.0 1.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.4 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.8 GO:0071565 nBAF complex(GO:0071565)
0.0 1.0 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 3.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.5 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.8 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.3 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.5 GO:0044447 axoneme part(GO:0044447)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 4.0 GO:0000785 chromatin(GO:0000785)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 2.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.7 GO:0005814 centriole(GO:0005814)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.6 1.9 GO:0008022 protein C-terminus binding(GO:0008022)
0.5 2.7 GO:0034046 poly(G) binding(GO:0034046)
0.5 3.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.5 2.3 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.4 1.2 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.4 1.5 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.3 1.4 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.3 1.0 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.3 1.0 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.3 2.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3 1.6 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.3 2.7 GO:0043515 kinetochore binding(GO:0043515)
0.3 1.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.3 2.0 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.3 2.0 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.3 1.4 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.2 1.1 GO:0060182 apelin receptor activity(GO:0060182)
0.2 1.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 0.6 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.2 2.7 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.2 1.0 GO:0015616 DNA translocase activity(GO:0015616)
0.2 0.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.4 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.8 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 2.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.7 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 1.4 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.1 0.5 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 1.3 GO:0016405 CoA-ligase activity(GO:0016405)
0.1 1.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 1.0 GO:0005522 profilin binding(GO:0005522)
0.1 0.7 GO:0070888 E-box binding(GO:0070888)
0.1 2.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.3 GO:0000035 acyl binding(GO:0000035)
0.1 1.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.7 GO:0008200 ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
0.1 0.4 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 0.8 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.6 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.7 GO:0035198 miRNA binding(GO:0035198)
0.1 0.4 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.7 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.6 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.9 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1 0.7 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.1 1.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 1.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 2.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.5 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.6 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 1.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 2.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.6 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 1.0 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 1.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.4 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 9.1 GO:0003924 GTPase activity(GO:0003924)
0.0 1.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0004096 catalase activity(GO:0004096)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 7.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.3 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.1 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.0 0.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.8 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0008061 chitin binding(GO:0008061)
0.0 1.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 3.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 1.1 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.3 GO:0042805 actinin binding(GO:0042805)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.0 GO:0045296 cadherin binding(GO:0045296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 0.6 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 5.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 3.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 0.9 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.0 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.1 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.4 PID ATR PATHWAY ATR signaling pathway
0.0 0.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 2.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 2.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 0.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 7.2 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.1 0.6 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 0.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 0.6 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 2.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.6 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 1.6 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 1.1 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.9 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.1 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 1.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling