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PRJEB1986: zebrafish developmental stages transcriptome

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Results for klf12b

Z-value: 1.20

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Transcription factors associated with klf12b

Gene Symbol Gene ID Gene Info
klf12b
ENSDARG00000032197 Kruppel-like factor 12b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
klf12bdr11_v1_chr9_+_30720048_307200480.427.7e-02Click!

Activity profile of klf12b motif

Sorted Z-values of klf12b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_25187210 5.49 ENSDART00000101147
ENSDART00000167528
si:dkey-183i3.5
si:dkey-183i3.5
chr6_+_13742899 4.51 ENSDART00000104722
cdk5r2a
cyclin-dependent kinase 5, regulatory subunit 2a (p39)
chr19_-_26863626 3.73 ENSDART00000145568
prrt1
proline-rich transmembrane protein 1
chr15_-_37846047 3.56 ENSDART00000184837
hsc70
heat shock cognate 70
chr5_-_25174420 2.41 ENSDART00000141554
abca2
ATP-binding cassette, sub-family A (ABC1), member 2
chr22_-_282498 2.36 ENSDART00000182766
CABZ01079178.1

chr5_-_67471375 2.30 ENSDART00000147009
si:dkey-251i10.2
si:dkey-251i10.2
chr13_-_11536951 2.15 ENSDART00000018155
adss
adenylosuccinate synthase
chr10_-_19497914 2.15 ENSDART00000132084
si:ch211-127i16.2
si:ch211-127i16.2
chr11_+_36989696 2.13 ENSDART00000045888
tkta
transketolase a
chr4_-_1324141 2.09 ENSDART00000180720
ptn
pleiotrophin
chr13_-_31166544 2.07 ENSDART00000146250
ENSDART00000132129
ENSDART00000139591
mapk8a
mitogen-activated protein kinase 8a
chr8_-_37263524 2.07 ENSDART00000061327
rh50
Rh50-like protein
chr5_-_22501663 2.00 ENSDART00000133174
si:dkey-27p18.5
si:dkey-27p18.5
chr18_-_46241775 1.99 ENSDART00000145999
ENSDART00000134244
ENSDART00000185021
ENSDART00000181855
prx
periaxin
chr9_-_35155089 1.94 ENSDART00000077901
appb
amyloid beta (A4) precursor protein b
chr22_-_263117 1.90 ENSDART00000158134
zgc:66156
zgc:66156
chr2_+_28672152 1.89 ENSDART00000157410
ENSDART00000169614
nadsyn1
NAD synthetase 1
chr22_+_7439186 1.82 ENSDART00000190667
zgc:92041
zgc:92041
chr2_+_54696042 1.82 ENSDART00000074270
ankrd12
ankyrin repeat domain 12
chr2_+_24203229 1.81 ENSDART00000138088
map4l
microtubule associated protein 4 like
chr17_+_18117358 1.75 ENSDART00000144894
bcl11ba
B cell CLL/lymphoma 11Ba
chr10_+_5135842 1.74 ENSDART00000132627
ENSDART00000162434
zgc:113274
zgc:113274
chr11_-_37509001 1.72 ENSDART00000109753
bsnb
bassoon (presynaptic cytomatrix protein) b
chr4_-_68563862 1.68 ENSDART00000182970
BX548011.2

chr1_-_44434707 1.66 ENSDART00000110148
cryba1l2
crystallin, beta A1, like 2
chr8_-_14050758 1.66 ENSDART00000133922
atp2b3a
ATPase plasma membrane Ca2+ transporting 3a
chr11_+_41135055 1.66 ENSDART00000173252
camta1
calmodulin binding transcription activator 1
chr19_+_164013 1.64 ENSDART00000167379
carmil1
capping protein regulator and myosin 1 linker 1
chr1_+_14283692 1.61 ENSDART00000017679
ppp2r2ca
protein phosphatase 2, regulatory subunit B, gamma a
chr20_+_5564042 1.56 ENSDART00000090934
ENSDART00000127050
nrxn3b
neurexin 3b
chr11_+_23957440 1.54 ENSDART00000190721
cntn2
contactin 2
chr23_-_39636195 1.54 ENSDART00000144439
vwa1
von Willebrand factor A domain containing 1
chr21_-_28235361 1.51 ENSDART00000164458
nrxn2a
neurexin 2a
chr20_+_6142433 1.50 ENSDART00000054084
ENSDART00000136986
ttr
transthyretin (prealbumin, amyloidosis type I)
chr25_+_12640211 1.50 ENSDART00000165108
jph3
junctophilin 3
chr17_-_15546862 1.49 ENSDART00000091021
col10a1a
collagen, type X, alpha 1a
chr8_-_25247284 1.47 ENSDART00000132697
gnat2
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr4_+_6643421 1.45 ENSDART00000099462
gpr85
G protein-coupled receptor 85
chr5_-_68927728 1.44 ENSDART00000132838
ank1a
ankyrin 1, erythrocytic a
chr25_-_4146947 1.43 ENSDART00000129268
fads2
fatty acid desaturase 2
chr7_-_24520866 1.43 ENSDART00000077039
faah2b
fatty acid amide hydrolase 2b
chr22_-_294700 1.43 ENSDART00000189179
CABZ01079179.1

chr14_-_8890437 1.42 ENSDART00000167242
ATG2A
si:ch73-45o6.2
chr2_+_47582681 1.42 ENSDART00000187579
scg2b
secretogranin II (chromogranin C), b
chr1_-_51465730 1.41 ENSDART00000074284
spred2a
sprouty-related, EVH1 domain containing 2a
chr8_-_53108207 1.41 ENSDART00000111023
b3galt4
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
chr7_+_21841037 1.40 ENSDART00000077503
tm4sf5
transmembrane 4 L six family member 5
chr10_+_22381802 1.37 ENSDART00000112484
nlgn2b
neuroligin 2b
chr15_+_37197494 1.37 ENSDART00000166203
aplp1
amyloid beta (A4) precursor-like protein 1
chr10_-_20637098 1.37 ENSDART00000080391
sprn2
shadow of prion protein 2
chr10_-_22828302 1.36 ENSDART00000079459
ENSDART00000100468
per1a
period circadian clock 1a
chr23_+_16633951 1.35 ENSDART00000109537
ENSDART00000193323
snphb
syntaphilin b
chr19_+_37458610 1.33 ENSDART00000103151
dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr23_-_24483311 1.33 ENSDART00000185793
ENSDART00000109248
spen
spen family transcriptional repressor
chr6_-_39006449 1.31 ENSDART00000150885
vdrb
vitamin D receptor b
chr21_+_6290566 1.31 ENSDART00000161647
fnbp1b
formin binding protein 1b
chr23_+_10352921 1.31 ENSDART00000081193
KRT18 (1 of many)
si:ch211-133j6.3
chr22_-_600016 1.30 ENSDART00000086434
tmcc2
transmembrane and coiled-coil domain family 2
chr16_-_12173554 1.29 ENSDART00000110567
ENSDART00000155935
clstn3
calsyntenin 3
chr15_-_12319065 1.28 ENSDART00000162973
ENSDART00000170543
fxyd6
FXYD domain containing ion transport regulator 6
chr24_+_40529346 1.25 ENSDART00000168548
CU929259.1

chr10_-_14929392 1.25 ENSDART00000137430
smad2
SMAD family member 2
chr23_+_44883805 1.24 ENSDART00000182805
si:ch73-361h17.1
si:ch73-361h17.1
chr13_+_25853757 1.23 ENSDART00000132521
bcl11aa
B cell CLL/lymphoma 11Aa
chr5_-_23317477 1.22 ENSDART00000090171
nlgn3b
neuroligin 3b
chr5_-_13076779 1.22 ENSDART00000192826
ypel1
yippee-like 1
chr20_+_19119800 1.22 ENSDART00000151881
rp1l1b
retinitis pigmentosa 1-like 1b
chr1_-_22512063 1.20 ENSDART00000031546
ENSDART00000190987
chrna6
cholinergic receptor, nicotinic, alpha 6
chr24_+_29381946 1.20 ENSDART00000189551
ntng1a
netrin g1a
chr2_+_22694382 1.19 ENSDART00000139196
kif1ab
kinesin family member 1Ab
chr21_-_43949208 1.18 ENSDART00000150983
camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr19_-_44089509 1.18 ENSDART00000189136
rad21b
RAD21 cohesin complex component b
chr21_+_6291027 1.17 ENSDART00000180467
ENSDART00000184952
ENSDART00000184006
fnbp1b
formin binding protein 1b
chr4_+_23223881 1.16 ENSDART00000133056
ENSDART00000089126
trhde.1
thyrotropin releasing hormone degrading enzyme, tandem duplicate 1
chr22_-_22130623 1.14 ENSDART00000113168
CU855878.1

chr5_-_38155005 1.14 ENSDART00000097770
gucy2d
guanylate cyclase 2D, retinal
chr4_-_77557279 1.13 ENSDART00000180113
AL935186.10

chr16_-_27749172 1.13 ENSDART00000145198
steap4
STEAP family member 4
chr21_+_10739846 1.12 ENSDART00000084011
cplx4a
complexin 4a
chr14_+_28281744 1.12 ENSDART00000173292
mid2
midline 2
chr9_+_49659114 1.11 ENSDART00000189643
CSRNP3
cysteine and serine rich nuclear protein 3
chr7_+_36539124 1.10 ENSDART00000173653
chd9
chromodomain helicase DNA binding protein 9
chr7_+_24573721 1.10 ENSDART00000173938
ENSDART00000173681
si:dkeyp-75h12.7
si:dkeyp-75h12.7
chr12_+_24344963 1.09 ENSDART00000191648
ENSDART00000183180
ENSDART00000088178
ENSDART00000189696
nrxn1a
neurexin 1a
chr18_+_18104235 1.08 ENSDART00000145342
cbln1
cerebellin 1 precursor
chr6_-_30210378 1.07 ENSDART00000157359
ENSDART00000113924
lrrc7
leucine rich repeat containing 7
chr4_-_23643272 1.07 ENSDART00000112301
ENSDART00000133184
trhde.2
thyrotropin releasing hormone degrading enzyme, tandem duplicate 2
chr22_+_7486867 1.07 ENSDART00000034586
CELA1 (1 of many)
zgc:112302
chr8_+_28900689 1.06 ENSDART00000141634
grid2
glutamate receptor, ionotropic, delta 2
chr6_+_40591149 1.05 ENSDART00000189060
ENSDART00000188298
frs3
fibroblast growth factor receptor substrate 3
chr24_+_29382109 1.05 ENSDART00000184620
ENSDART00000188414
ENSDART00000186132
ENSDART00000191489
ntng1a
netrin g1a
chr11_+_23933016 1.04 ENSDART00000000486
cntn2
contactin 2
chr10_+_20180163 1.04 ENSDART00000080016
ppp3ccb
protein phosphatase 3, catalytic subunit, gamma isozyme, b
chr18_-_37007294 1.03 ENSDART00000088309
map3k10
mitogen-activated protein kinase kinase kinase 10
chr10_+_29698467 1.03 ENSDART00000163402
dlg2
discs, large homolog 2 (Drosophila)
chr15_+_24212847 1.03 ENSDART00000155502
sez6b
seizure related 6 homolog b
chr13_+_28702104 1.02 ENSDART00000135481
si:ch211-67n3.9
si:ch211-67n3.9
chr18_-_15771551 1.02 ENSDART00000130931
ENSDART00000154079
si:ch211-219a15.3
si:ch211-219a15.3
chr6_-_39158953 1.01 ENSDART00000050682
stat2
signal transducer and activator of transcription 2
chr14_-_2209742 1.01 ENSDART00000054889
pcdh2ab5
protocadherin 2 alpha b 5
chr24_+_39137001 1.01 ENSDART00000181086
ENSDART00000183724
ENSDART00000193466
tbc1d24
TBC1 domain family, member 24
chr6_+_24817852 1.01 ENSDART00000165609
barhl2
BarH-like homeobox 2
chr14_-_2213660 1.00 ENSDART00000162537
pcdh2ab3
protocadherin 2 alpha b 3
chr1_-_12160981 1.00 ENSDART00000162146
b4galt1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr6_-_7842078 0.99 ENSDART00000065507
plppr2b
phospholipid phosphatase related 2b
chr5_+_20148671 0.99 ENSDART00000143205
svopa
SV2 related protein a
chr19_-_13733870 0.98 ENSDART00000177773
epb41a
erythrocyte membrane protein band 4.1a
chr4_+_20263097 0.98 ENSDART00000138820
lrtm2a
leucine-rich repeats and transmembrane domains 2a
chr25_+_19955598 0.98 ENSDART00000091547
kcna1a
potassium voltage-gated channel, shaker-related subfamily, member 1a
chr11_-_27874116 0.98 ENSDART00000180579
eif4g3a
eukaryotic translation initiation factor 4 gamma, 3a
chr17_-_51829310 0.98 ENSDART00000154544
numb
numb homolog (Drosophila)
chr20_-_31781941 0.97 ENSDART00000139417
stxbp5a
syntaxin binding protein 5a (tomosyn)
chr18_-_37007061 0.96 ENSDART00000136432
map3k10
mitogen-activated protein kinase kinase kinase 10
chr23_-_8373676 0.96 ENSDART00000105135
ENSDART00000158531
oprl1
opiate receptor-like 1
chr4_+_19535946 0.96 ENSDART00000192342
ENSDART00000183740
ENSDART00000180812
ENSDART00000180017
lrrc4.1
leucine rich repeat containing 4.1
chr9_+_54290896 0.95 ENSDART00000149175
pou4f3
POU class 4 homeobox 3
chr16_-_44512882 0.95 ENSDART00000191241
CR925804.2

chr16_-_40727455 0.95 ENSDART00000162331
si:dkey-22o22.2
si:dkey-22o22.2
chr17_+_43623598 0.94 ENSDART00000154138
znf365
zinc finger protein 365
chr2_+_9822319 0.94 ENSDART00000144078
ENSDART00000144371
anxa13l
annexin A13, like
chr3_-_40955780 0.94 ENSDART00000130130
cyp3c3
cytochrome P450, family 3, subfamily c, polypeptide 3
chr21_-_12272543 0.94 ENSDART00000081510
ENSDART00000151297
celf4
CUGBP, Elav-like family member 4
chr15_-_9593532 0.93 ENSDART00000169912
gab2
GRB2-associated binding protein 2
chr5_-_21970881 0.93 ENSDART00000182907
arhgef9a
Cdc42 guanine nucleotide exchange factor (GEF) 9a
chr23_+_19590598 0.93 ENSDART00000170149
slmapb
sarcolemma associated protein b
chr16_+_6944311 0.93 ENSDART00000144763
eaf1
ELL associated factor 1
chr22_-_10482253 0.93 ENSDART00000143164
aspn
asporin (LRR class 1)
chr20_+_1412193 0.93 ENSDART00000064419
leg1.1
liver-enriched gene 1, tandem duplicate 1
chr14_-_14607855 0.92 ENSDART00000162322
rab9b
RAB9B, member RAS oncogene family
chr9_-_32604414 0.92 ENSDART00000088876
ENSDART00000166502
satb2
SATB homeobox 2
chr23_+_16638639 0.92 ENSDART00000143545
snphb
syntaphilin b
chr21_+_21195487 0.91 ENSDART00000181746
ENSDART00000184832
rictorb
RPTOR independent companion of MTOR, complex 2b
chr24_-_11325849 0.90 ENSDART00000182485
myrip
myosin VIIA and Rab interacting protein
chr15_-_26686908 0.90 ENSDART00000185254
pitpnm3
PITPNM family member 3
chr18_-_12612699 0.90 ENSDART00000090335
hipk2
homeodomain interacting protein kinase 2
chr13_-_5937034 0.90 ENSDART00000045292
spred2b
sprouty-related, EVH1 domain containing 2b
chr17_-_36896560 0.89 ENSDART00000045287
mapre3a
microtubule-associated protein, RP/EB family, member 3a
chr7_-_57933736 0.89 ENSDART00000142580
ank2b
ankyrin 2b, neuronal
chr20_-_1378514 0.88 ENSDART00000181830
scara5
scavenger receptor class A, member 5 (putative)
chr25_-_19090479 0.88 ENSDART00000027465
ENSDART00000177670
cacna2d4b
calcium channel, voltage-dependent, alpha 2/delta subunit 4b
chr12_+_16233077 0.87 ENSDART00000152409
mpp3b
membrane protein, palmitoylated 3b (MAGUK p55 subfamily member 3)
chr18_-_16179129 0.87 ENSDART00000125353
slc6a15
solute carrier family 6 (neutral amino acid transporter), member 15
chr3_+_23247325 0.86 ENSDART00000114190
ppp1r9ba
protein phosphatase 1, regulatory subunit 9Ba
chr5_+_52039067 0.86 ENSDART00000143276
setbp1
SET binding protein 1
chr3_-_37476475 0.85 ENSDART00000148107
si:ch211-278a6.1
si:ch211-278a6.1
chr5_-_38506981 0.85 ENSDART00000097822
atp1b2b
ATPase Na+/K+ transporting subunit beta 2b
chr13_-_32648382 0.85 ENSDART00000138571
ENSDART00000132820
bend3
BEN domain containing 3
chr24_-_31123365 0.85 ENSDART00000182947
tmem56a
transmembrane protein 56a
chr5_-_65782783 0.85 ENSDART00000130888
ENSDART00000050855
notch1b
notch 1b
chr9_-_4598883 0.85 ENSDART00000171927
galnt13
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13
chr2_-_57076687 0.84 ENSDART00000161523
slc25a42
solute carrier family 25, member 42
chr10_+_5159475 0.84 ENSDART00000142507
cdc42se2
CDC42 small effector 2
chr8_-_22826996 0.84 ENSDART00000146563
magixa
MAGI family member, X-linked a
chr12_+_42574148 0.84 ENSDART00000157855
ebf3a
early B cell factor 3a
chr3_-_18373604 0.84 ENSDART00000148132
spag9a
sperm associated antigen 9a
chr13_+_12801092 0.83 ENSDART00000164040
ENSDART00000134725
si:ch211-233a24.2
si:ch211-233a24.2
chr15_-_1962326 0.83 ENSDART00000179669
dock10
dedicator of cytokinesis 10
chr5_-_18046053 0.82 ENSDART00000144898
rnf215
ring finger protein 215
chr10_+_35953068 0.82 ENSDART00000015279
rtn4rl1a
reticulon 4 receptor-like 1a
chr18_-_22753637 0.82 ENSDART00000181589
ENSDART00000009912
hsf4
heat shock transcription factor 4
chr9_-_11655031 0.82 ENSDART00000044314
itgav
integrin, alpha V
chr8_+_26565512 0.82 ENSDART00000140980
sema3bl
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl
chr1_-_56080112 0.82 ENSDART00000075469
ENSDART00000161473
c3a.6
complement component c3a, duplicate 6
chr1_-_46859398 0.82 ENSDART00000135795
agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr25_-_13105310 0.81 ENSDART00000172269
smpd3
sphingomyelin phosphodiesterase 3, neutral
chr25_+_37126921 0.81 ENSDART00000124331
si:ch1073-174d20.1
si:ch1073-174d20.1
chr20_+_46897504 0.81 ENSDART00000158124
si:ch73-21k16.1
si:ch73-21k16.1
chr18_-_14937211 0.81 ENSDART00000141893
mlc1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr10_+_25222367 0.81 ENSDART00000042767
grm5a
glutamate receptor, metabotropic 5a
chr2_+_55916911 0.80 ENSDART00000189483
ENSDART00000183647
ENSDART00000083470
atcayb
ataxia, cerebellar, Cayman type b
chr12_-_25217217 0.80 ENSDART00000152931
kcng3
potassium voltage-gated channel, subfamily G, member 3
chr10_+_439692 0.80 ENSDART00000147740
zdhhc8a
zinc finger, DHHC-type containing 8a
chr16_+_16849220 0.80 ENSDART00000047409
ENSDART00000142155
myh14
myosin, heavy chain 14, non-muscle
chr21_+_24536233 0.79 ENSDART00000145448
ENSDART00000109886
ENSDART00000135191
anapc13
anaphase promoting complex subunit 13
chr15_-_36249087 0.79 ENSDART00000157190
ostn
osteocrin
chr3_+_16722014 0.79 ENSDART00000008711
gys1
glycogen synthase 1 (muscle)
chr5_-_41638039 0.79 ENSDART00000144525
epg5
ectopic P-granules autophagy protein 5 homolog (C. elegans)
chr19_-_3488860 0.78 ENSDART00000172520
hivep1
human immunodeficiency virus type I enhancer binding protein 1
chr3_-_2593859 0.78 ENSDART00000143826
si:dkey-217f16.5
si:dkey-217f16.5
chr7_+_34620418 0.78 ENSDART00000081338
slc9a5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr1_-_21483832 0.78 ENSDART00000102790
glrba
glycine receptor, beta a
chr2_+_258698 0.77 ENSDART00000181330
ENSDART00000181645
phlpp1
PH domain and leucine rich repeat protein phosphatase 1
chr16_+_37470717 0.77 ENSDART00000112003
ENSDART00000188431
ENSDART00000192837
adgrb1a
adhesion G protein-coupled receptor B1a
chr2_-_14390627 0.77 ENSDART00000172367
sgip1b
SH3-domain GRB2-like (endophilin) interacting protein 1b
chr9_-_27442339 0.76 ENSDART00000138602
stxbp5l
syntaxin binding protein 5-like
chr14_+_8328645 0.76 ENSDART00000127494
nrg2b
neuregulin 2b
chr3_+_40841897 0.76 ENSDART00000150081
ENSDART00000126096
mmd2a
monocyte to macrophage differentiation-associated 2a
chr5_-_57641257 0.76 ENSDART00000149282
hspb2
heat shock protein, alpha-crystallin-related, b2
chr22_+_16446052 0.75 ENSDART00000142454
si:dkey-121a11.3
si:dkey-121a11.3
chr7_-_30082931 0.75 ENSDART00000075600
tspan3b
tetraspanin 3b
chr8_+_25247245 0.75 ENSDART00000045798
ampd2b
adenosine monophosphate deaminase 2b
chr9_+_40939336 0.74 ENSDART00000100386
mstnb
myostatin b
chr22_+_696931 0.74 ENSDART00000149712
ENSDART00000009756
gpr37l1a
G protein-coupled receptor 37 like 1a
chr23_+_21544227 0.74 ENSDART00000140253
arhgef10lb
Rho guanine nucleotide exchange factor (GEF) 10-like b
chr20_+_38201644 0.73 ENSDART00000022694
ehd3
EH-domain containing 3
chr12_+_2381213 0.73 ENSDART00000188007
LO018238.1

chr22_+_5103349 0.73 ENSDART00000083474
atcaya
ataxia, cerebellar, Cayman type a
chr19_+_27479838 0.73 ENSDART00000103922
atat1
alpha tubulin acetyltransferase 1
chr17_+_16564921 0.73 ENSDART00000151904
foxn3
forkhead box N3

Network of associatons between targets according to the STRING database.

First level regulatory network of klf12b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.5 1.6 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.5 2.3 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.4 2.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.3 1.2 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.3 2.0 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.3 1.1 GO:0015677 copper ion import(GO:0015677)
0.3 0.8 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.3 0.8 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.3 2.1 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.2 0.7 GO:0097264 self proteolysis(GO:0097264)
0.2 1.4 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.2 3.6 GO:0042026 protein refolding(GO:0042026)
0.2 2.6 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.2 0.9 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.2 0.6 GO:0043455 regulation of secondary metabolic process(GO:0043455)
0.2 1.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.2 0.8 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 0.7 GO:1901862 negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle tissue development(GO:1901862)
0.2 0.9 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.2 0.9 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 1.7 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.2 1.9 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.2 0.7 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.2 0.5 GO:2000793 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.2 1.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 1.5 GO:0072337 modified amino acid transport(GO:0072337)
0.1 0.4 GO:0033210 leptin-mediated signaling pathway(GO:0033210) cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.1 1.5 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.1 0.9 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 1.9 GO:0009435 NAD biosynthetic process(GO:0009435)
0.1 2.8 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.1 0.4 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.9 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 1.0 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.1 1.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 1.7 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.7 GO:0008584 male gonad development(GO:0008584)
0.1 0.4 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.1 0.3 GO:2000376 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.1 1.5 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 0.9 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 1.0 GO:0019233 sensory perception of pain(GO:0019233)
0.1 0.9 GO:1990402 embryonic liver development(GO:1990402)
0.1 0.3 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.8 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.8 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.5 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 0.9 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.8 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 1.3 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 0.8 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.0 GO:0034340 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 0.5 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.1 1.1 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1 1.3 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 0.5 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.1 0.8 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 0.5 GO:0030194 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 0.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.8 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.9 GO:0014812 muscle cell migration(GO:0014812)
0.1 1.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 0.9 GO:0001964 startle response(GO:0001964)
0.1 1.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 3.9 GO:0010842 retina layer formation(GO:0010842)
0.1 0.4 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 0.7 GO:0032264 IMP salvage(GO:0032264)
0.1 0.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.5 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.0 1.7 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 1.3 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.3 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.3 GO:0090303 positive regulation of wound healing(GO:0090303)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.5 GO:0034605 cellular response to heat(GO:0034605)
0.0 1.2 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.7 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 1.3 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 2.5 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.8 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.9 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.3 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.5 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.8 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 1.4 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.0 0.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.3 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 2.1 GO:0003146 heart jogging(GO:0003146)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.6 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.3 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 2.0 GO:0007254 JNK cascade(GO:0007254)
0.0 3.9 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.4 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.9 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:2000434 regulation of protein neddylation(GO:2000434)
0.0 0.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 1.6 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.5 GO:0099565 chemical synaptic transmission, postsynaptic(GO:0099565)
0.0 5.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.8 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:0044857 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.6 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 1.1 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.6 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 1.0 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.4 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.7 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.2 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.4 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370) mRNA methylation(GO:0080009)
0.0 0.3 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 1.1 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.2 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 2.0 GO:0048675 axon extension(GO:0048675)
0.0 0.5 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.2 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.0 1.0 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 1.1 GO:0050919 negative chemotaxis(GO:0050919)
0.0 1.0 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.0 2.1 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.5 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.2 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.3 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 1.1 GO:0014904 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 0.2 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.5 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 1.0 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.4 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.5 GO:0034250 positive regulation of cellular amide metabolic process(GO:0034250) positive regulation of translation(GO:0045727)
0.0 0.8 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.8 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.5 GO:0009612 response to mechanical stimulus(GO:0009612)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.5 1.4 GO:0060077 inhibitory synapse(GO:0060077)
0.2 2.3 GO:0044295 axonal growth cone(GO:0044295)
0.2 1.0 GO:0005955 calcineurin complex(GO:0005955)
0.2 1.7 GO:0098982 GABA-ergic synapse(GO:0098982)
0.2 1.2 GO:0034991 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 0.9 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 2.2 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 0.8 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 1.2 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.5 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.9 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 0.4 GO:0030314 junctional membrane complex(GO:0030314)
0.1 1.0 GO:0033270 paranode region of axon(GO:0033270) juxtaparanode region of axon(GO:0044224)
0.1 1.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 1.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.8 GO:0017119 Golgi transport complex(GO:0017119)
0.1 1.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.4 GO:0001650 fibrillar center(GO:0001650)
0.1 0.9 GO:0030315 T-tubule(GO:0030315)
0.1 1.3 GO:0043195 terminal bouton(GO:0043195)
0.1 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 4.5 GO:0005882 intermediate filament(GO:0005882)
0.0 1.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.8 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 1.3 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.9 GO:0035371 microtubule plus-end(GO:0035371)
0.0 5.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 3.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.5 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.2 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 3.8 GO:0014069 postsynaptic density(GO:0014069)
0.0 2.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.9 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.2 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.8 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.4 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 1.4 GO:0030141 secretory granule(GO:0030141)
0.0 0.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.5 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.5 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.2 GO:0000795 synaptonemal complex(GO:0000795)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.4 1.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.4 2.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.3 4.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3 0.9 GO:0030882 lipid antigen binding(GO:0030882)
0.3 1.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 0.8 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.3 1.3 GO:0070644 vitamin D response element binding(GO:0070644)
0.2 1.0 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.2 3.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 2.0 GO:0004359 glutaminase activity(GO:0004359)
0.2 2.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 2.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 0.8 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.2 1.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 0.9 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 0.9 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.2 1.0 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 1.9 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.2 0.8 GO:0008432 JUN kinase binding(GO:0008432)
0.2 0.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 0.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.6 GO:0070052 collagen V binding(GO:0070052)
0.1 0.5 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.8 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 3.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 1.0 GO:0004985 opioid receptor activity(GO:0004985)
0.1 1.8 GO:0045159 myosin II binding(GO:0045159)
0.1 0.3 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.1 0.5 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.1 2.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.7 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.6 GO:0031779 melanocortin receptor binding(GO:0031779)
0.1 1.2 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.8 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 2.1 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.2 GO:0052833 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.8 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.7 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 1.2 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.0 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.3 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.1 0.4 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 5.2 GO:0008201 heparin binding(GO:0008201)
0.1 1.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 2.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 1.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.0 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.3 GO:0031769 glucagon receptor binding(GO:0031769)
0.1 0.8 GO:0005080 protein kinase C binding(GO:0005080)
0.1 1.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 2.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.9 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.7 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.9 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.5 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.0 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.5 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 1.1 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 1.4 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.9 GO:0017022 myosin binding(GO:0017022)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.7 GO:0052744 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.0 0.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.3 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.1 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.4 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.9 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 2.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.8 GO:0042626 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 0.1 GO:0001607 neuromedin U receptor activity(GO:0001607)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 1.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 3.0 GO:0003774 motor activity(GO:0003774)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 1.3 GO:0004896 cytokine receptor activity(GO:0004896)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 PID CONE PATHWAY Visual signal transduction: Cones
0.2 1.0 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 1.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 1.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 0.2 PID IL23 PATHWAY IL23-mediated signaling events
0.1 2.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 0.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.5 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.1 PID SHP2 PATHWAY SHP2 signaling
0.0 0.1 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 2.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID BMP PATHWAY BMP receptor signaling
0.0 0.6 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.6 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.3 ST GA13 PATHWAY G alpha 13 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.1 REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR Genes involved in Downstream signaling of activated FGFR
0.4 1.2 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.2 2.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 1.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 2.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.4 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1 0.8 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.0 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 0.4 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 0.8 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 1.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 3.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.8 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.5 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 1.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.9 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 1.4 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism