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PRJEB1986: zebrafish developmental stages transcriptome

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Results for lhx1a+lhx1b

Z-value: 0.25

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Transcription factors associated with lhx1a+lhx1b

Gene Symbol Gene ID Gene Info
lhx1b
ENSDARG00000007944 LIM homeobox 1b
lhx1a
ENSDARG00000014018 LIM homeobox 1a
lhx1b
ENSDARG00000111635 LIM homeobox 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lhx1bdr11_v1_chr5_+_56268436_562684360.589.9e-03Click!
lhx1adr11_v1_chr15_-_27710513_27710575-0.194.5e-01Click!

Activity profile of lhx1a+lhx1b motif

Sorted Z-values of lhx1a+lhx1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_16422654 0.96 ENSDART00000150149
tdp1
tyrosyl-DNA phosphodiesterase 1
chr7_-_17297156 0.63 ENSDART00000161336
nitr11a
novel immune-type receptor 11a
chr3_-_19368435 0.48 ENSDART00000132987
s1pr5a
sphingosine-1-phosphate receptor 5a
chr4_+_57881965 0.35 ENSDART00000162234
si:dkeyp-44b5.4
si:dkeyp-44b5.4
chr16_+_54209504 0.34 ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr6_-_50730749 0.34 ENSDART00000157153
ENSDART00000110441
pigu
phosphatidylinositol glycan anchor biosynthesis, class U
chr3_+_40164129 0.33 ENSDART00000102526
gfer
growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)
chr9_-_27398369 0.33 ENSDART00000186499
tex30
testis expressed 30
chr2_+_38373272 0.31 ENSDART00000113111
psmb5
proteasome subunit beta 5
chr7_+_20471315 0.31 ENSDART00000173714
si:dkey-19b23.13
si:dkey-19b23.13
chr3_-_15999501 0.30 ENSDART00000160668
nme3
NME/NM23 nucleoside diphosphate kinase 3
chr24_-_38657683 0.30 ENSDART00000154843
si:ch1073-164k15.3
si:ch1073-164k15.3
chr3_-_26806032 0.29 ENSDART00000143710
pigq
phosphatidylinositol glycan anchor biosynthesis, class Q
chr22_-_14247276 0.28 ENSDART00000033332
si:ch211-246m6.5
si:ch211-246m6.5
chr5_+_60590796 0.28 ENSDART00000159859
tmem132e
transmembrane protein 132E
chr3_-_26787430 0.28 ENSDART00000087047
rab40c
RAB40c, member RAS oncogene family
chr25_-_21031007 0.28 ENSDART00000138985
gnaia
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr23_+_20640484 0.28 ENSDART00000054691
uba1
ubiquitin-like modifier activating enzyme 1
chr1_-_669717 0.27 ENSDART00000160564
cyyr1
cysteine/tyrosine-rich 1
chr20_-_45812144 0.27 ENSDART00000147897
ENSDART00000147637
fermt1
fermitin family member 1
chr12_+_13118540 0.27 ENSDART00000077840
ENSDART00000127870
cmn
calymmin
chr11_-_10456553 0.26 ENSDART00000169509
ENSDART00000185574
ENSDART00000188276
ect2
epithelial cell transforming 2
chr5_+_41477954 0.26 ENSDART00000185871
pias2
protein inhibitor of activated STAT, 2
chr24_+_21514283 0.26 ENSDART00000007066
cdk8
cyclin-dependent kinase 8
chr2_-_30668580 0.26 ENSDART00000087270
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr1_-_45616470 0.25 ENSDART00000150165
atf7ip
activating transcription factor 7 interacting protein
chr19_+_7424347 0.25 ENSDART00000004622
sf3b4
splicing factor 3b, subunit 4
chr4_+_77943184 0.25 ENSDART00000159094
pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr22_-_5252005 0.25 ENSDART00000132942
ENSDART00000081801
ncln
nicalin
chr9_+_37152564 0.24 ENSDART00000189497
gli2a
GLI family zinc finger 2a
chr2_+_105748 0.24 ENSDART00000169601
CABZ01098670.1

chr12_-_35830625 0.24 ENSDART00000180028
CU459056.1

chr14_+_16287968 0.24 ENSDART00000106593
prpf19
pre-mRNA processing factor 19
chr11_-_10456387 0.24 ENSDART00000011087
ENSDART00000081827
ect2
epithelial cell transforming 2
chr23_-_16485190 0.24 ENSDART00000155038
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr6_-_12912606 0.23 ENSDART00000164640
ical1
islet cell autoantigen 1-like
chr6_-_34838397 0.23 ENSDART00000060169
ENSDART00000169605
mier1a
mesoderm induction early response 1a, transcriptional regulator
chr5_+_41477526 0.22 ENSDART00000153567
pias2
protein inhibitor of activated STAT, 2
chr2_+_25315591 0.22 ENSDART00000161386
fndc3ba
fibronectin type III domain containing 3Ba
chr25_+_22320738 0.21 ENSDART00000073566
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr13_+_11440389 0.21 ENSDART00000186463
zbtb18
zinc finger and BTB domain containing 18
chr21_+_42717424 0.21 ENSDART00000166936
ENSDART00000172135
sh3pxd2b
SH3 and PX domains 2B
chr10_+_17235370 0.21 ENSDART00000038780
sppl3
signal peptide peptidase 3
chr1_+_21731382 0.20 ENSDART00000054395
pax5
paired box 5
chr21_+_25802190 0.19 ENSDART00000128987
nf2b
neurofibromin 2b (merlin)
chr15_+_9861973 0.19 ENSDART00000170945
si:dkey-13m3.2
si:dkey-13m3.2
chr20_+_11731039 0.19 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
si:ch211-155o21.3
chr3_+_26342768 0.19 ENSDART00000163832
si:ch211-156b7.4
si:ch211-156b7.4
chr18_+_46382484 0.19 ENSDART00000024202
ENSDART00000142790
daw1
dynein assembly factor with WDR repeat domains 1
chr9_-_14504834 0.19 ENSDART00000056103
nrp2b
neuropilin 2b
chr20_-_9095105 0.19 ENSDART00000140792
oma1
OMA1 zinc metallopeptidase
chr22_-_24285432 0.18 ENSDART00000164083
si:ch211-117l17.4
si:ch211-117l17.4
chr20_+_25586099 0.18 ENSDART00000063122
ENSDART00000134047
cyp2p10
cytochrome P450, family 2, subfamily P, polypeptide 10
chr8_+_50953776 0.18 ENSDART00000013870
zgc:56596
zgc:56596
chr22_-_22242884 0.17 ENSDART00000020937
hdgfl2
HDGF like 2
chr6_-_35052145 0.17 ENSDART00000073970
ENSDART00000185790
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr7_+_22809905 0.17 ENSDART00000166900
ENSDART00000143455
ENSDART00000126037
sf1
splicing factor 1
chr5_-_31901468 0.17 ENSDART00000147814
ENSDART00000141446
coro1cb
coronin, actin binding protein, 1Cb
chr17_+_24318753 0.17 ENSDART00000064083
otx1
orthodenticle homeobox 1
chr18_+_14619544 0.17 ENSDART00000010821
utp4
UTP4, small subunit processome component
chr6_+_11989537 0.17 ENSDART00000190817
baz2ba
bromodomain adjacent to zinc finger domain, 2Ba
chr16_-_42965192 0.16 ENSDART00000113714
mtx1a
metaxin 1a
chr1_-_21287724 0.16 ENSDART00000193900
npy1r
neuropeptide Y receptor Y1
chr24_+_21540842 0.15 ENSDART00000091529
wasf3b
WAS protein family, member 3b
chr1_+_10318089 0.15 ENSDART00000029774
pip4p1b
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1b
chr15_-_35112937 0.15 ENSDART00000154565
ENSDART00000099642
zgc:77118
zgc:77118
chr16_-_16761164 0.15 ENSDART00000135872
si:dkey-27n14.1
si:dkey-27n14.1
chr21_-_17482465 0.15 ENSDART00000004548
barhl1b
BarH-like homeobox 1b
chr4_-_9891874 0.14 ENSDART00000067193
adm2a
adrenomedullin 2a
chr23_+_12406722 0.14 ENSDART00000145008
pigt
phosphatidylinositol glycan anchor biosynthesis, class T
chr8_-_53926228 0.14 ENSDART00000015554
ubiad1
UbiA prenyltransferase domain containing 1
chr6_-_55399214 0.13 ENSDART00000168367
ctsa
cathepsin A
chr18_+_8320165 0.13 ENSDART00000092053
chkb
choline kinase beta
chr4_+_69191065 0.13 ENSDART00000170595
znf1075
zinc finger protein 1075
chr6_-_44402358 0.13 ENSDART00000193007
ENSDART00000193603
pdzrn3b
PDZ domain containing RING finger 3b
chr21_-_25801956 0.13 ENSDART00000101219
mettl27
methyltransferase like 27
chr2_+_10878406 0.12 ENSDART00000091497
tceanc2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr1_-_51038885 0.12 ENSDART00000035150
spast
spastin
chr14_+_44794936 0.12 ENSDART00000128881
zgc:195212
zgc:195212
chr4_+_38188797 0.12 ENSDART00000133264
si:ch211-229l10.11
si:ch211-229l10.11
chr23_-_16484383 0.12 ENSDART00000187839
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr22_-_36530902 0.12 ENSDART00000056188
polr2h
info polymerase (RNA) II (DNA directed) polypeptide H
chr8_-_16712111 0.11 ENSDART00000184147
ENSDART00000180419
ENSDART00000076600
rpe65c
retinal pigment epithelium-specific protein 65c
chr8_-_49728590 0.11 ENSDART00000135714
ENSDART00000138810
ENSDART00000098319
gkap1
G kinase anchoring protein 1
chr20_-_28642061 0.11 ENSDART00000135513
rgs6
regulator of G protein signaling 6
chr9_-_43644261 0.11 ENSDART00000023684
cwc22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr11_-_41853874 0.11 ENSDART00000002556
mrto4
MRT4 homolog, ribosome maturation factor
chr22_-_10156581 0.11 ENSDART00000168304
rbck1
RanBP-type and C3HC4-type zinc finger containing 1
chr1_+_6172786 0.11 ENSDART00000126468
prkag3a
protein kinase, AMP-activated, gamma 3a non-catalytic subunit
chr19_+_2631565 0.10 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr21_+_6151953 0.10 ENSDART00000131854
si:dkey-93m18.6
si:dkey-93m18.6
chr15_-_43284021 0.10 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr8_-_30979494 0.10 ENSDART00000138959
si:ch211-251j10.3
si:ch211-251j10.3
chr7_+_21272833 0.09 ENSDART00000052942
serpinh2
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr20_+_6035427 0.09 ENSDART00000054086
tshr
thyroid stimulating hormone receptor
chr23_-_31969786 0.09 ENSDART00000134550
ormdl2
ORMDL sphingolipid biosynthesis regulator 2
chr24_-_40860603 0.09 ENSDART00000188032
CU633479.7

chr17_+_51682429 0.09 ENSDART00000004379
nol10
nucleolar protein 10
chr11_+_17984354 0.09 ENSDART00000179986
rpusd4
RNA pseudouridylate synthase domain containing 4
chr6_-_40029423 0.09 ENSDART00000103230
pfkfb4b
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b
chr16_+_23303859 0.08 ENSDART00000006093
slc50a1
solute carrier family 50 (sugar efflux transporter), member 1
chr2_+_20406399 0.08 ENSDART00000006817
ENSDART00000137848
palmda
palmdelphin a
chr8_+_19504011 0.08 ENSDART00000158859
ENSDART00000159044
sec22bb
SEC22 homolog B, vesicle trafficking protein b
chr3_+_3681116 0.08 ENSDART00000109618
art4
ADP-ribosyltransferase 4 (Dombrock blood group)
chr4_+_52212057 0.08 ENSDART00000165627
znf1034
zinc finger protein 1034
chr23_+_4709607 0.08 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
raf1a
raf1a
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr17_-_10122204 0.08 ENSDART00000160751
BX088587.1

chr25_+_18711804 0.08 ENSDART00000011149
fam185a
family with sequence similarity 185, member A
chr24_+_28953089 0.07 ENSDART00000153761
rnpc3
RNA-binding region (RNP1, RRM) containing 3
chr24_+_26328787 0.07 ENSDART00000003884
mynn
myoneurin
chr23_+_17509794 0.07 ENSDART00000148457
gid8b
GID complex subunit 8 homolog b (S. cerevisiae)
chr19_+_46158078 0.07 ENSDART00000183933
ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr23_-_18567088 0.07 ENSDART00000192371
sephs2
selenophosphate synthetase 2
chr24_+_26329018 0.07 ENSDART00000145752
mynn
myoneurin
chr16_+_13965923 0.07 ENSDART00000103857
zgc:162509
zgc:162509
chr7_+_4474880 0.07 ENSDART00000143528
si:dkey-83f18.14
si:dkey-83f18.14
chr13_-_12602920 0.07 ENSDART00000102311
lrit3b
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3b
chr6_-_21582444 0.06 ENSDART00000151339
si:dkey-43k4.3
si:dkey-43k4.3
chr17_+_22577472 0.06 ENSDART00000045099
yipf4
Yip1 domain family, member 4
chr4_+_49266048 0.06 ENSDART00000127767
ENSDART00000186362
si:ch211-42i6.2
si:ch211-42i6.2
chr13_+_33268657 0.05 ENSDART00000002095
tmem39b
transmembrane protein 39B
chr17_-_25831569 0.05 ENSDART00000148743
hhat
hedgehog acyltransferase
chr8_-_12867128 0.05 ENSDART00000142201
slc2a6
solute carrier family 2 (facilitated glucose transporter), member 6
chr21_-_13972745 0.05 ENSDART00000143874
akna
AT-hook transcription factor
chr22_-_28226948 0.05 ENSDART00000147686
si:dkey-222p3.1
si:dkey-222p3.1
chr6_-_35052388 0.04 ENSDART00000181000
ENSDART00000170116
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr4_+_16885854 0.04 ENSDART00000017726
etnk1
ethanolamine kinase 1
chr18_-_41161828 0.04 ENSDART00000114993
CABZ01005876.1

chr23_+_4689626 0.04 ENSDART00000131532
gp9
glycoprotein IX (platelet)
chr13_-_9450210 0.04 ENSDART00000133768
pimr152
Pim proto-oncogene, serine/threonine kinase, related 152
chr11_-_40204621 0.04 ENSDART00000086287
znf362a
zinc finger protein 362a
chr8_-_53044300 0.03 ENSDART00000191653
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr17_+_45405821 0.03 ENSDART00000189482
ENSDART00000177422
tagapa
T cell activation RhoGTPase activating protein a
chr13_+_35528607 0.03 ENSDART00000075414
ENSDART00000112947
wdr27
WD repeat domain 27
chr8_+_43340995 0.03 ENSDART00000038566
rflna
refilin A
chr4_+_72723304 0.03 ENSDART00000186791
ENSDART00000158902
ENSDART00000191925
rab3ip
RAB3A interacting protein (rabin3)
chr15_-_20939579 0.02 ENSDART00000152371
usp2a
ubiquitin specific peptidase 2a
chr6_+_35052721 0.02 ENSDART00000191090
ENSDART00000082940
uhmk1
U2AF homology motif (UHM) kinase 1
chr10_-_2524917 0.02 ENSDART00000188642
CU856539.1

chr2_-_16217344 0.02 ENSDART00000152031
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr5_-_23843636 0.02 ENSDART00000193280
GBGT1 (1 of many)
si:ch211-135f11.5
chr25_-_13490744 0.02 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr23_-_4409668 0.02 ENSDART00000081823
si:ch73-142c19.1
si:ch73-142c19.1
chr10_-_11261386 0.02 ENSDART00000189946
ptbp3
polypyrimidine tract binding protein 3
chr11_+_13032483 0.01 ENSDART00000108968
ptgfr
prostaglandin F receptor (FP)
chr3_+_23029484 0.01 ENSDART00000187900
nags
N-acetylglutamate synthase
chr22_-_20812822 0.01 ENSDART00000193778
dot1l
DOT1-like histone H3K79 methyltransferase
chr6_+_17053650 0.01 ENSDART00000155296
pimr16
Pim proto-oncogene, serine/threonine kinase, related 16
chr25_+_4855549 0.01 ENSDART00000163839
ap4e1
adaptor-related protein complex 4, epsilon 1 subunit
chr1_+_51039558 0.01 ENSDART00000024743
dpy30
dpy-30 histone methyltransferase complex regulatory subunit
chr7_+_27317174 0.01 ENSDART00000193058
sox6
SRY (sex determining region Y)-box 6
chr25_+_22296666 0.01 ENSDART00000138887
ENSDART00000193410
cyp11a2
cytochrome P450, family 11, subfamily A, polypeptide 2
chr13_+_646700 0.01 ENSDART00000006892
tp53bp2a
tumor protein p53 binding protein, 2a
chr14_-_14607855 0.01 ENSDART00000162322
rab9b
RAB9B, member RAS oncogene family
chr14_-_451555 0.01 ENSDART00000190906
FAT4
FAT atypical cadherin 4
chr16_+_26113457 0.00 ENSDART00000183537
BX571738.1

chr14_-_413273 0.00 ENSDART00000163976
ENSDART00000179907
FAT4
FAT atypical cadherin 4
chr3_-_31619463 0.00 ENSDART00000124559
moto
minamoto
chr20_+_46202188 0.00 ENSDART00000100523
taar13c
trace amine associated receptor 13c
chr5_+_33498253 0.00 ENSDART00000140993
ms4a17c.2
membrane-spanning 4-domains, subfamily A, member 17c.2
chr19_-_14970813 0.00 ENSDART00000184312
CR394532.2

Network of associatons between targets according to the STRING database.

First level regulatory network of lhx1a+lhx1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0000012 single strand break repair(GO:0000012)
0.1 0.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.2 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.1 0.2 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.1 0.3 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 0.3 GO:0031112 positive regulation of microtubule polymerization or depolymerization(GO:0031112)
0.0 0.1 GO:0071498 vitamin K metabolic process(GO:0042373) cellular response to fluid shear stress(GO:0071498)
0.0 0.5 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.2 GO:0071800 podosome assembly(GO:0071800)
0.0 0.1 GO:0016108 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.0 0.3 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.3 GO:0044857 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.2 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.1 GO:0090153 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.6 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.2 GO:0060004 reflex(GO:0060004) vestibular reflex(GO:0060005) vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.3 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.2 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.2 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.0 0.5 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.3 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.2 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.2 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.2 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175) superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.8 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.3 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors