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PRJEB1986: zebrafish developmental stages transcriptome

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Results for lhx5

Z-value: 0.68

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Transcription factors associated with lhx5

Gene Symbol Gene ID Gene Info
lhx5
ENSDARG00000057936 LIM homeobox 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lhx5dr11_v1_chr21_-_15929041_15929041-0.391.0e-01Click!

Activity profile of lhx5 motif

Sorted Z-values of lhx5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_22099536 2.55 ENSDART00000101923
CR391987.1

chr6_+_7444899 2.46 ENSDART00000053775
arf3b
ADP-ribosylation factor 3b
chr17_-_37395460 2.28 ENSDART00000148160
ENSDART00000075975
crip1
cysteine-rich protein 1
chr3_-_11624694 2.12 ENSDART00000127157
hlfa
hepatic leukemia factor a
chr25_+_31227747 1.87 ENSDART00000033872
tnni2a.1
troponin I type 2a (skeletal, fast), tandem duplicate 1
chr5_+_2815021 1.86 ENSDART00000020472
hpda
4-hydroxyphenylpyruvate dioxygenase a
chr16_-_28658341 1.84 ENSDART00000148456
abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr3_-_59297532 1.75 ENSDART00000187991
CABZ01053748.1

chr19_-_26869103 1.69 ENSDART00000089699
prrt1
proline-rich transmembrane protein 1
chr15_-_37850969 1.64 ENSDART00000031418
hsc70
heat shock cognate 70
chr15_-_44601331 1.64 ENSDART00000161514
zgc:165508
zgc:165508
chr3_-_48716422 1.58 ENSDART00000164979
si:ch211-114m9.1
si:ch211-114m9.1
chr19_+_43297546 1.55 ENSDART00000168002
laptm5
lysosomal protein transmembrane 5
chr16_+_2820340 1.52 ENSDART00000092299
ENSDART00000192931
ENSDART00000148512
si:dkey-288i20.2
si:dkey-288i20.2
chr9_-_22147567 1.45 ENSDART00000110941
crygm2d14
crystallin, gamma M2d14
chr21_+_21195487 1.44 ENSDART00000181746
ENSDART00000184832
rictorb
RPTOR independent companion of MTOR, complex 2b
chr15_-_46718759 1.43 ENSDART00000085926
ENSDART00000154577
zgc:162872
zgc:162872
chr6_+_39905021 1.41 ENSDART00000064904
endou
endonuclease, polyU-specific
chr20_-_2949028 1.36 ENSDART00000104667
ENSDART00000193151
ENSDART00000131946
cdk19
cyclin-dependent kinase 19
chr10_+_45089820 1.35 ENSDART00000175481
camk2b2
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr9_+_34641237 1.34 ENSDART00000133996
shox
short stature homeobox
chr25_-_19420949 1.29 ENSDART00000181338
map1ab
microtubule-associated protein 1Ab
chr12_-_17712393 1.25 ENSDART00000143534
ENSDART00000010144
pvalb2
parvalbumin 2
chr10_-_2524297 1.15 ENSDART00000192475
CU856539.1

chr9_+_2574122 1.13 ENSDART00000166326
ENSDART00000191822
CIR1
si:ch73-167c12.2
chr17_-_200316 1.10 ENSDART00000190561
CABZ01083778.1

chr19_+_5480327 1.09 ENSDART00000148794
jupb
junction plakoglobin b
chr24_-_11309477 1.09 ENSDART00000137257
myrip
myosin VIIA and Rab interacting protein
chr7_-_71829649 1.08 ENSDART00000160449
cacnb2a
calcium channel, voltage-dependent, beta 2a
chr4_-_18309917 1.06 ENSDART00000189084
plxnc1
plexin C1
chr16_-_38118003 1.06 ENSDART00000058667
si:dkey-23o4.6
si:dkey-23o4.6
chr13_-_29421331 1.05 ENSDART00000150228
chata
choline O-acetyltransferase a
chr23_-_17509656 1.05 ENSDART00000148423
dnajc5ab
DnaJ (Hsp40) homolog, subfamily C, member 5ab
chr10_+_17776981 1.04 ENSDART00000141693
ccl19b
chemokine (C-C motif) ligand 19b
chr10_+_38417512 1.02 ENSDART00000112457
samsn1b
SAM domain, SH3 domain and nuclear localisation signals 1b
chr21_-_20939488 1.00 ENSDART00000039043
rgs7bpb
regulator of G protein signaling 7 binding protein b
chr23_-_18024543 1.00 ENSDART00000139695
pm20d1.1
peptidase M20 domain containing 1, tandem duplicate 1
chr20_+_52389858 0.99 ENSDART00000185863
ENSDART00000166651
arhgap39
Rho GTPase activating protein 39
chr9_+_54039006 0.99 ENSDART00000112441
tlr7
toll-like receptor 7
chr18_+_15644559 0.98 ENSDART00000061794
nr1h4
nuclear receptor subfamily 1, group H, member 4
chr7_-_71531846 0.98 ENSDART00000111797
acer2
alkaline ceramidase 2
chr5_-_6377865 0.97 ENSDART00000031775
zgc:73226
zgc:73226
chr12_-_6880694 0.96 ENSDART00000171846
pcdh15b
protocadherin-related 15b
chr6_-_28980756 0.95 ENSDART00000014661
glmnb
glomulin, FKBP associated protein b
chr7_+_24573721 0.94 ENSDART00000173938
ENSDART00000173681
si:dkeyp-75h12.7
si:dkeyp-75h12.7
chr20_+_32552912 0.93 ENSDART00000009691
scml4
Scm polycomb group protein like 4
chr23_+_16638639 0.92 ENSDART00000143545
snphb
syntaphilin b
chr16_-_28856112 0.92 ENSDART00000078543
syt11b
synaptotagmin XIb
chr5_-_41494831 0.91 ENSDART00000051081
eef2l2
eukaryotic translation elongation factor 2, like 2
chr24_-_7697274 0.90 ENSDART00000186077
syt5b
synaptotagmin Vb
chr16_+_51326237 0.88 ENSDART00000168525
CU469384.1

chr8_+_52637507 0.86 ENSDART00000163830
si:dkey-90l8.3
si:dkey-90l8.3
chr17_-_23616626 0.84 ENSDART00000104730
ifit14
interferon-induced protein with tetratricopeptide repeats 14
chr19_-_47323267 0.82 ENSDART00000190077
CU138512.1

chr12_+_45200744 0.81 ENSDART00000098932
wbp2
WW domain binding protein 2
chr23_-_1660708 0.79 ENSDART00000175138
CU693481.1

chr4_-_2219705 0.79 ENSDART00000131046
si:ch73-278m9.1
si:ch73-278m9.1
chr6_-_43677125 0.79 ENSDART00000150128
foxp1b
forkhead box P1b
chr17_+_16564921 0.78 ENSDART00000151904
foxn3
forkhead box N3
chr5_-_21422390 0.77 ENSDART00000144198
tenm1
teneurin transmembrane protein 1
chr1_+_6862917 0.76 ENSDART00000182953
erbb4a
erb-b2 receptor tyrosine kinase 4a
chr6_-_57539141 0.76 ENSDART00000156967
itcha
itchy E3 ubiquitin protein ligase a
chr25_+_3994823 0.75 ENSDART00000154020
eps8l2
EPS8 like 2
chr17_-_16965809 0.75 ENSDART00000153697
nrxn3a
neurexin 3a
chr2_+_2223837 0.74 ENSDART00000101038
ENSDART00000129354
tmie
transmembrane inner ear
chr9_+_54290896 0.73 ENSDART00000149175
pou4f3
POU class 4 homeobox 3
chr2_-_9059955 0.73 ENSDART00000022768
ak5
adenylate kinase 5
chr23_-_39666519 0.73 ENSDART00000110868
ENSDART00000190961
vwa1
von Willebrand factor A domain containing 1
chr3_+_39853788 0.73 ENSDART00000154869
cacna1ha
calcium channel, voltage-dependent, T type, alpha 1H subunit a
chr7_-_74057288 0.72 ENSDART00000189740
CU929544.1

chr11_-_45141309 0.72 ENSDART00000181736
cant1b
calcium activated nucleotidase 1b
chr7_-_66868543 0.71 ENSDART00000149680
ampd3a
adenosine monophosphate deaminase 3a
chr20_-_5291012 0.70 ENSDART00000122892
cyp46a1.3
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3
chr15_-_46779934 0.70 ENSDART00000085136
clcn2c
chloride channel 2c
chr2_+_20430366 0.70 ENSDART00000155108
si:ch211-153l6.6
si:ch211-153l6.6
chr21_-_44081540 0.69 ENSDART00000130833
FO704810.1

chr9_+_38074082 0.68 ENSDART00000017833
cacnb4a
calcium channel, voltage-dependent, beta 4a subunit
chr17_+_28533102 0.65 ENSDART00000156218
mdga2a
MAM domain containing glycosylphosphatidylinositol anchor 2a
chr6_-_1865323 0.65 ENSDART00000155775
dlgap4b
discs, large (Drosophila) homolog-associated protein 4b
chr23_+_26946429 0.65 ENSDART00000185564
cacnb3b
calcium channel, voltage-dependent, beta 3b
chr24_-_31425799 0.65 ENSDART00000157998
cngb3.1
cyclic nucleotide gated channel beta 3, tandem duplicate 1
chr22_-_14739491 0.65 ENSDART00000133385
lrp1ba
low density lipoprotein receptor-related protein 1Ba
chr9_+_7998794 0.64 ENSDART00000138167
myo16
myosin XVI
chr15_+_9327252 0.64 ENSDART00000144381
sgcg
sarcoglycan, gamma
chr1_-_55785722 0.63 ENSDART00000142069
ENSDART00000043933
ndufb7
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7
chr22_-_31060579 0.63 ENSDART00000182376
cand2
cullin-associated and neddylation-dissociated 2 (putative)
chr25_-_27621268 0.63 ENSDART00000146205
ENSDART00000073511
hyal6
hyaluronoglucosaminidase 6
chr6_-_39649504 0.63 ENSDART00000179960
ENSDART00000190951
larp4ab
La ribonucleoprotein domain family, member 4Ab
chr4_-_75678082 0.61 ENSDART00000180201
si:dkey-165o8.1
si:dkey-165o8.1
chr2_+_42072231 0.61 ENSDART00000084517
vcpip1
valosin containing protein (p97)/p47 complex interacting protein 1
chr25_-_25058508 0.61 ENSDART00000087570
ENSDART00000178891
FQ311928.1

chr10_+_16584382 0.60 ENSDART00000112039
CR790388.1

chr1_+_54124209 0.60 ENSDART00000187730
LO017722.1

chr24_+_9475809 0.60 ENSDART00000132688
si:ch211-285f17.1
si:ch211-285f17.1
chr23_+_31405497 0.59 ENSDART00000053546
sh3bgrl2
SH3 domain binding glutamate-rich protein like 2
chr12_+_18681477 0.59 ENSDART00000127981
ENSDART00000143979
rgs9b
regulator of G protein signaling 9b
chr1_-_15797663 0.59 ENSDART00000177122
SGCZ
sarcoglycan zeta
chr9_+_24159280 0.58 ENSDART00000184624
ENSDART00000178422
hecw2a
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2a
chr17_+_38476300 0.58 ENSDART00000123298
stard9
StAR-related lipid transfer (START) domain containing 9
chr5_+_69747417 0.58 ENSDART00000153717
si:ch211-275j6.5
si:ch211-275j6.5
chr16_-_31622777 0.57 ENSDART00000137311
ENSDART00000002930
phf20l1
PHD finger protein 20 like 1
chr15_+_34592215 0.57 ENSDART00000099776
tspan13a
tetraspanin 13a
chr1_+_44127292 0.56 ENSDART00000160542
cabp2a
calcium binding protein 2a
chr3_+_45687266 0.56 ENSDART00000131652
gpr146
G protein-coupled receptor 146
chr15_-_17618800 0.55 ENSDART00000157185
adamts15b
ADAM metallopeptidase with thrombospondin type 1 motif, 15b
chr15_-_40267485 0.54 ENSDART00000152253
kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr25_-_9805269 0.54 ENSDART00000192048
lrrc4c
leucine rich repeat containing 4C
chr21_-_22635245 0.54 ENSDART00000115224
ENSDART00000101782
nectin1a
nectin cell adhesion molecule 1a
chr4_+_20536120 0.52 ENSDART00000125685
zmp:0000000650
zmp:0000000650
chr3_+_7808459 0.51 ENSDART00000162374
hook2
hook microtubule-tethering protein 2
chr1_-_50438247 0.51 ENSDART00000114098
dkk2
dickkopf WNT signaling pathway inhibitor 2
chr19_-_5769728 0.51 ENSDART00000133106
si:ch211-264f5.6
si:ch211-264f5.6
chr21_+_27278120 0.51 ENSDART00000193882
si:dkey-175m17.7
si:dkey-175m17.7
chr11_-_26832685 0.50 ENSDART00000153519
iqsec1b
IQ motif and Sec7 domain 1b
chr10_-_2524917 0.49 ENSDART00000188642
CU856539.1

chr20_-_43663494 0.48 ENSDART00000144564
BX470188.1

chr4_-_5019113 0.48 ENSDART00000189321
ENSDART00000081990
strip2
striatin interacting protein 2
chr22_+_30047245 0.48 ENSDART00000142857
ENSDART00000141247
ENSDART00000140015
ENSDART00000040538
add3a
adducin 3 (gamma) a
chr9_+_24159725 0.46 ENSDART00000137756
hecw2a
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2a
chr10_-_43404027 0.46 ENSDART00000086227
edil3b
EGF-like repeats and discoidin I-like domains 3b
chr19_-_5769553 0.46 ENSDART00000175003
si:ch211-264f5.6
si:ch211-264f5.6
chr7_+_59212666 0.46 ENSDART00000172046
dok1b
docking protein 1b
chr21_-_39327223 0.45 ENSDART00000115097
aifm5
apoptosis-inducing factor, mitochondrion-associated, 5
chr17_-_40956035 0.44 ENSDART00000124715
si:dkey-16j16.4
si:dkey-16j16.4
chr12_+_1139690 0.44 ENSDART00000160442
CABZ01072885.1

chr24_-_33873451 0.44 ENSDART00000159840
asic1c
acid-sensing (proton-gated) ion channel 1c
chr5_-_48664522 0.44 ENSDART00000083229
mblac2
metallo-beta-lactamase domain containing 2
chr12_-_48006835 0.44 ENSDART00000108989
adamts14
ADAM metallopeptidase with thrombospondin type 1 motif, 14
chr5_-_38094130 0.43 ENSDART00000131831
si:ch211-284e13.4
si:ch211-284e13.4
chr16_-_41004731 0.42 ENSDART00000102591
KCNV1
si:dkey-201i6.2
chr8_+_36500061 0.42 ENSDART00000185840
slc7a4
solute carrier family 7, member 4
chr10_-_13343831 0.41 ENSDART00000135941
il11ra
interleukin 11 receptor, alpha
chr18_+_35128685 0.41 ENSDART00000151579
si:ch211-195m9.3
si:ch211-195m9.3
chr5_+_13427826 0.41 ENSDART00000083359
sec14l8
SEC14-like lipid binding 8
chr22_+_19366866 0.41 ENSDART00000137301
si:dkey-21e2.12
si:dkey-21e2.12
chr9_-_9415000 0.40 ENSDART00000146210
si:ch211-214p13.9
si:ch211-214p13.9
chr20_-_13774826 0.39 ENSDART00000063831
opn8c
opsin 8, group member c
chr15_-_14552101 0.39 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr14_-_32631013 0.39 ENSDART00000176815
atp11c
ATPase phospholipid transporting 11C
chr14_-_48765262 0.39 ENSDART00000166463
cnot6b
CCR4-NOT transcription complex, subunit 6b
chr17_+_49281597 0.38 ENSDART00000155599
zgc:113176
zgc:113176
chr16_-_25829779 0.38 ENSDART00000086301
irge4
immunity-related GTPase family, e4
chr11_-_45140227 0.38 ENSDART00000184062
cant1b
calcium activated nucleotidase 1b
chr8_+_7801060 0.37 ENSDART00000161618
tfe3a
transcription factor binding to IGHM enhancer 3a
chr14_-_32631519 0.37 ENSDART00000167282
ENSDART00000052938
atp11c
ATPase phospholipid transporting 11C
chr21_-_2814709 0.36 ENSDART00000097664
SEMA4D
semaphorin 4D
chr11_+_40812590 0.36 ENSDART00000186690
errfi1a
ERBB receptor feedback inhibitor 1a
chr6_+_52350443 0.36 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
si:ch211-239j9.1
chr24_-_35767501 0.36 ENSDART00000105680
ENSDART00000042290
ENSDART00000166264
dtna
dystrobrevin, alpha
chr8_-_25569920 0.36 ENSDART00000136869
prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr13_-_9886579 0.35 ENSDART00000101926
si:ch211-117n7.7
si:ch211-117n7.7
chr1_-_9195629 0.35 ENSDART00000143587
ENSDART00000192174
ern2
endoplasmic reticulum to nucleus signaling 2
chr14_+_36521005 0.34 ENSDART00000192286
TENM3
si:dkey-237h12.3
chr23_+_39970425 0.34 ENSDART00000165376
fyco1a
FYVE and coiled-coil domain containing 1a
chr2_+_49799470 0.34 ENSDART00000146325
si:ch211-190k17.19
si:ch211-190k17.19
chr9_-_37749973 0.33 ENSDART00000087663
sema5ba
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Ba
chr8_+_36560019 0.33 ENSDART00000136418
ENSDART00000061378
ENSDART00000185237
sf3a1
splicing factor 3a, subunit 1
chr23_-_20051369 0.33 ENSDART00000049836
bgnb
biglycan b
chr17_-_45040813 0.33 ENSDART00000075514
entpd5a
ectonucleoside triphosphate diphosphohydrolase 5a
chr9_-_42418470 0.32 ENSDART00000144353
calcrla
calcitonin receptor-like a
chr23_+_42810055 0.32 ENSDART00000186647
myl9a
myosin, light chain 9a, regulatory
chr22_-_13466246 0.32 ENSDART00000134035
cntnap5b
contactin associated protein-like 5b
chr5_-_42904329 0.32 ENSDART00000112807
cxcl20
chemokine (C-X-C motif) ligand 20
chr11_+_30057762 0.31 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr25_+_4751879 0.31 ENSDART00000169465
si:zfos-2372e4.1
si:zfos-2372e4.1
chr11_-_34478225 0.29 ENSDART00000189604
xxylt1
xyloside xylosyltransferase 1
chr14_-_7207961 0.29 ENSDART00000167994
ENSDART00000166532
stox2b
storkhead box 2b
chr15_-_22074315 0.29 ENSDART00000149830
drd2a
dopamine receptor D2a
chr1_+_51721851 0.28 ENSDART00000040397
prdx2
peroxiredoxin 2
chr11_+_45436703 0.28 ENSDART00000168295
ENSDART00000173293
sos1
son of sevenless homolog 1 (Drosophila)
chr7_-_7692992 0.27 ENSDART00000192619
aadat
aminoadipate aminotransferase
chr12_+_7497882 0.26 ENSDART00000134608
phyhiplb
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr4_-_1801519 0.25 ENSDART00000188604
ENSDART00000135749
nudt4b
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr21_-_35534401 0.25 ENSDART00000112308
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr10_-_11261565 0.24 ENSDART00000146727
ptbp3
polypyrimidine tract binding protein 3
chr8_-_31062811 0.24 ENSDART00000142528
slc20a1a
solute carrier family 20, member 1a
chr9_-_50001606 0.23 ENSDART00000161648
ENSDART00000168514
scn1a
sodium channel, voltage-gated, type I, alpha
chr14_-_451555 0.23 ENSDART00000190906
FAT4
FAT atypical cadherin 4
chr22_-_20812822 0.22 ENSDART00000193778
dot1l
DOT1-like histone H3K79 methyltransferase
chr9_+_55154414 0.22 ENSDART00000182924
ANOS1
anosmin 1
chr8_+_36500308 0.20 ENSDART00000098701
slc7a4
solute carrier family 7, member 4
chr1_+_41498188 0.20 ENSDART00000191934
ENSDART00000146310
dtx4
deltex 4, E3 ubiquitin ligase
chr8_-_11834599 0.20 ENSDART00000190986
rapgef1a
Rap guanine nucleotide exchange factor (GEF) 1a
chr22_+_19552987 0.19 ENSDART00000105315
hsd11b1la
hydroxysteroid (11-beta) dehydrogenase 1-like a
chr13_-_2010191 0.19 ENSDART00000161021
ENSDART00000124134
gfral
GDNF family receptor alpha like
chr4_+_12966640 0.19 ENSDART00000113357
vhll
von Hippel-Lindau tumor suppressor like
chr23_+_41800052 0.19 ENSDART00000141484
pdyn
prodynorphin
chr9_-_12811936 0.19 ENSDART00000188490
myo10l3
myosin X-like 3
chr4_+_2482046 0.18 ENSDART00000103371
zdhhc17
zinc finger, DHHC-type containing 17
chr8_+_43340995 0.17 ENSDART00000038566
rflna
refilin A
chr2_+_20605925 0.16 ENSDART00000191510
olfml2bb
olfactomedin-like 2Bb
chr11_-_44979281 0.16 ENSDART00000190972
ldb1b
LIM-domain binding 1b
chr7_-_7692723 0.16 ENSDART00000183352
aadat
aminoadipate aminotransferase
chr18_+_5172848 0.15 ENSDART00000190642
CABZ01080599.1

chr4_+_5255041 0.15 ENSDART00000137966
ccdc167
coiled-coil domain containing 167
chr14_+_16151368 0.15 ENSDART00000160973
polr1a
polymerase (RNA) I polypeptide A
chr17_-_27048537 0.15 ENSDART00000050018
ENSDART00000193861
cnksr1
connector enhancer of kinase suppressor of Ras 1
chr11_-_2838699 0.15 ENSDART00000066189
lhfpl5a
LHFPL tetraspan subfamily member 5a
chr4_+_9669717 0.15 ENSDART00000004604
si:dkey-153k10.9
si:dkey-153k10.9
chr7_-_50410524 0.15 ENSDART00000083346
hypk
huntingtin interacting protein K

Network of associatons between targets according to the STRING database.

First level regulatory network of lhx5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.4 1.6 GO:0099563 modification of synaptic structure(GO:0099563)
0.4 1.1 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.3 1.0 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.3 1.9 GO:0006572 tyrosine catabolic process(GO:0006572)
0.3 0.8 GO:0042546 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.2 1.0 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.2 1.1 GO:0002159 desmosome assembly(GO:0002159)
0.2 0.7 GO:0021611 facial nerve formation(GO:0021611)
0.2 0.6 GO:0010265 SCF complex assembly(GO:0010265)
0.2 0.9 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.2 0.5 GO:0044650 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.2 0.6 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.1 0.4 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.1 0.5 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 1.4 GO:0038203 TORC2 signaling(GO:0038203)
0.1 1.0 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 0.8 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 1.6 GO:0042026 protein refolding(GO:0042026)
0.1 1.0 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 1.0 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 0.3 GO:0046462 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.3 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 0.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 2.0 GO:0009636 response to toxic substance(GO:0009636)
0.1 0.7 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.4 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.0 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 1.8 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.2 GO:1903011 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011)
0.1 0.2 GO:0034729 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.1 0.4 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.7 GO:0032264 IMP salvage(GO:0032264)
0.1 1.1 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 0.3 GO:0071543 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 2.0 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.7 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.8 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.7 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.7 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 1.3 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 2.4 GO:0060048 cardiac muscle contraction(GO:0060048)
0.0 0.3 GO:0055062 phosphate ion homeostasis(GO:0055062) trivalent inorganic anion homeostasis(GO:0072506)
0.0 0.8 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 1.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.3 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.6 GO:0006415 translational termination(GO:0006415)
0.0 1.0 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 1.2 GO:0030282 bone mineralization(GO:0030282)
0.0 0.3 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.8 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.0 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.8 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.3 GO:0036230 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.4 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.5 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.9 GO:0006414 translational elongation(GO:0006414)
0.0 0.0 GO:0036076 ligamentous ossification(GO:0036076)
0.0 0.9 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.4 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.1 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.0 0.6 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 1.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.9 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.4 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.9 GO:0031045 dense core granule(GO:0031045)
0.1 1.4 GO:0031932 TORC2 complex(GO:0031932)
0.1 1.1 GO:0030057 desmosome(GO:0030057)
0.1 1.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 1.0 GO:0032420 stereocilium(GO:0032420)
0.0 3.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.9 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.0 0.6 GO:0044545 NSL complex(GO:0044545)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 1.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.9 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 1.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 2.2 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.6 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.0 GO:0097255 R2TP complex(GO:0097255)
0.0 0.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.4 GO:0030424 axon(GO:0030424)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.6 1.8 GO:0015562 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.3 1.0 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.3 0.8 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 1.0 GO:0032052 bile acid binding(GO:0032052)
0.1 1.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.7 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.1 1.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.3 GO:0001605 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.1 0.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.5 GO:0039706 co-receptor binding(GO:0039706)
0.1 1.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 1.0 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.4 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 1.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.3 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.1 0.7 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.4 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 1.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.6 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.2 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.1 1.4 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.3 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.6 GO:0005222 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.6 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 1.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.5 GO:0033691 sialic acid binding(GO:0033691)
0.0 1.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.8 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 1.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 1.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.1 GO:0017022 myosin binding(GO:0017022)
0.0 0.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.7 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 1.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.2 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.9 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.2 GO:0005504 fatty acid binding(GO:0005504)
0.0 1.4 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 2.1 GO:0042277 peptide binding(GO:0042277)
0.0 0.6 GO:0017124 SH3 domain binding(GO:0017124)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 3.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport