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PRJEB1986: zebrafish developmental stages transcriptome

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Results for lhx6

Z-value: 0.34

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Transcription factors associated with lhx6

Gene Symbol Gene ID Gene Info
lhx6
ENSDARG00000006896 LIM homeobox 6
lhx6
ENSDARG00000112520 LIM homeobox 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lhx6dr11_v1_chr10_+_9372702_93727020.541.7e-02Click!

Activity profile of lhx6 motif

Sorted Z-values of lhx6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_22099536 1.20 ENSDART00000101923
CR391987.1

chr3_-_31079186 1.17 ENSDART00000145636
ENSDART00000140569
ELOB (1 of many)
elob
elongin B
elongin B
chr10_-_11385155 1.09 ENSDART00000064214
plac8.1
placenta-specific 8, tandem duplicate 1
chr3_-_50443607 0.85 ENSDART00000074036
rcvrna
recoverin a
chr8_-_23780334 0.79 ENSDART00000145179
ENSDART00000145894
zgc:195245
zgc:195245
chr17_-_37395460 0.74 ENSDART00000148160
ENSDART00000075975
crip1
cysteine-rich protein 1
chr5_-_50992690 0.68 ENSDART00000149553
ENSDART00000097460
ENSDART00000192021
hmgcra
3-hydroxy-3-methylglutaryl-CoA reductase a
chr22_+_7738966 0.64 ENSDART00000147073
si:ch73-44m9.5
si:ch73-44m9.5
chr1_-_50859053 0.62 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr16_-_11798994 0.61 ENSDART00000135408
cnfn
cornifelin
chr6_-_55585423 0.60 ENSDART00000157129
slc12a5a
solute carrier family 12 (potassium/chloride transporter), member 5a
chr23_-_19230627 0.55 ENSDART00000007122
guca1b
guanylate cyclase activator 1B
chr2_+_50608099 0.52 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr17_+_15433518 0.52 ENSDART00000026180
fabp7a
fatty acid binding protein 7, brain, a
chr17_+_15433671 0.51 ENSDART00000149568
fabp7a
fatty acid binding protein 7, brain, a
chr11_+_38280454 0.50 ENSDART00000171496
CDK18
si:dkey-166c18.1
chr4_+_21129752 0.49 ENSDART00000169764
syt1a
synaptotagmin Ia
chr16_+_46111849 0.48 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr20_-_40755614 0.48 ENSDART00000061247
cx32.3
connexin 32.3
chr8_+_16025554 0.48 ENSDART00000110171
elavl4
ELAV like neuron-specific RNA binding protein 4
chr22_+_27090136 0.47 ENSDART00000136770
si:dkey-246e1.3
si:dkey-246e1.3
chr1_-_23308225 0.47 ENSDART00000137567
ENSDART00000008201
smim14
small integral membrane protein 14
chr5_+_64732270 0.47 ENSDART00000134241
olfm1a
olfactomedin 1a
chr23_+_40460333 0.47 ENSDART00000184658
soga3b
SOGA family member 3b
chr15_+_6114109 0.46 ENSDART00000184937
PCP4 (1 of many)
Purkinje cell protein 4
chr6_+_9870192 0.44 ENSDART00000150894
MPP4 (1 of many)
si:ch211-222n4.6
chr4_+_11384891 0.44 ENSDART00000092381
ENSDART00000186577
ENSDART00000191054
ENSDART00000191584
pcloa
piccolo presynaptic cytomatrix protein a
chr20_-_2134620 0.44 ENSDART00000064375
tmem244
transmembrane protein 244
chr3_-_61162750 0.44 ENSDART00000055064
pvalb8
parvalbumin 8
chr21_+_42226113 0.43 ENSDART00000170362
GABRB2 (1 of many)
gamma-aminobutyric acid type A receptor beta2 subunit
chr21_-_22827548 0.43 ENSDART00000079161
angptl5
angiopoietin-like 5
chr14_+_15155684 0.43 ENSDART00000167966
zgc:158852
zgc:158852
chr5_+_64732036 0.42 ENSDART00000073950
olfm1a
olfactomedin 1a
chr20_-_9436521 0.42 ENSDART00000133000
zgc:101840
zgc:101840
chr14_+_17376940 0.41 ENSDART00000054590
ENSDART00000010148
spon2b
spondin 2b, extracellular matrix protein
chr21_-_18993110 0.40 ENSDART00000144086
si:ch211-222n4.6
si:ch211-222n4.6
chr15_+_47903864 0.39 ENSDART00000063835
otx5
orthodenticle homolog 5
chr9_+_34641237 0.39 ENSDART00000133996
shox
short stature homeobox
chr3_+_23092762 0.39 ENSDART00000142884
ENSDART00000024136
gngt2a
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr14_+_40874608 0.39 ENSDART00000168448
si:ch211-106m9.1
si:ch211-106m9.1
chr4_+_12612723 0.39 ENSDART00000133767
lmo3
LIM domain only 3
chr14_-_33105434 0.38 ENSDART00000163795
dlg3
discs, large homolog 3 (Drosophila)
chr23_+_21966447 0.38 ENSDART00000189378
lactbl1a
lactamase, beta-like 1a
chr12_-_4781801 0.38 ENSDART00000167490
ENSDART00000121718
mapta
microtubule-associated protein tau a
chr14_-_33872092 0.37 ENSDART00000111903
si:ch73-335m24.2
si:ch73-335m24.2
chr18_-_20869175 0.37 ENSDART00000090079
synm
synemin, intermediate filament protein
chr1_+_25801648 0.36 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr10_-_27049170 0.35 ENSDART00000143451
cnih2
cornichon family AMPA receptor auxiliary protein 2
chr14_-_30587814 0.35 ENSDART00000144912
ENSDART00000149714
tmem265
transmembrane protein 265
chr17_-_200316 0.35 ENSDART00000190561
CABZ01083778.1

chr6_-_12588044 0.35 ENSDART00000047896
slc15a1b
solute carrier family 15 (oligopeptide transporter), member 1b
chr24_+_13316737 0.33 ENSDART00000191658
SBSPON
somatomedin B and thrombospondin type 1 domain containing
chr5_+_61301525 0.33 ENSDART00000128773
doc2b
double C2-like domains, beta
chr9_-_43538328 0.32 ENSDART00000140526
znf385b
zinc finger protein 385B
chr12_+_41697664 0.32 ENSDART00000162302
bnip3
BCL2 interacting protein 3
chr16_+_31804590 0.32 ENSDART00000167321
wnt4b
wingless-type MMTV integration site family, member 4b
chr20_-_34750363 0.31 ENSDART00000152845
znf395b
zinc finger protein 395b
chr14_-_33872616 0.31 ENSDART00000162840
si:ch73-335m24.2
si:ch73-335m24.2
chr25_-_27564205 0.30 ENSDART00000157319
hyal4
hyaluronoglucosaminidase 4
chr21_+_21340864 0.29 ENSDART00000183151
sdhaf1
succinate dehydrogenase complex assembly factor 1
chr3_+_34919810 0.29 ENSDART00000055264
ca10b
carbonic anhydrase Xb
chr21_+_28958471 0.29 ENSDART00000144331
ENSDART00000005929
ppp3ca
protein phosphatase 3, catalytic subunit, alpha isozyme
chr14_+_25817628 0.29 ENSDART00000047680
glra1
glycine receptor, alpha 1
chr15_+_9072821 0.29 ENSDART00000154463
si:dkey-202g17.3
si:dkey-202g17.3
chr2_+_20332044 0.29 ENSDART00000112131
plppr4a
phospholipid phosphatase related 4a
chr16_+_34531486 0.29 ENSDART00000043291
paqr7b
progestin and adipoQ receptor family member VII, b
chr2_-_5505094 0.29 ENSDART00000145035
saga
S-antigen; retina and pineal gland (arrestin) a
chr20_-_46362606 0.28 ENSDART00000153087
bmf2
BCL2 modifying factor 2
chr20_-_16171297 0.28 ENSDART00000012476
coa7
cytochrome c oxidase assembly factor 7
chr10_+_21726853 0.28 ENSDART00000162869
pcdh1g14
protocadherin 1 gamma 14
chr10_-_42519773 0.28 ENSDART00000039187
march5l
membrane-associated ring finger (C3HC4) 5, like
chr16_+_47207691 0.28 ENSDART00000062507
ica1
islet cell autoantigen 1
chr7_-_49594995 0.28 ENSDART00000174161
ENSDART00000109147
brsk2b
BR serine/threonine kinase 2b
chr3_+_32553714 0.28 ENSDART00000165638
pax10
paired box 10
chr7_+_30787903 0.27 ENSDART00000174000
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr13_+_38521152 0.27 ENSDART00000145292
adgrb3
adhesion G protein-coupled receptor B3
chr12_-_32421046 0.27 ENSDART00000075567
enpp7.1
ectonucleotide pyrophosphatase/phosphodiesterase 7, tandem duplicate 1
chr20_-_48604199 0.27 ENSDART00000161762
ENSDART00000170894
mgst3a
microsomal glutathione S-transferase 3a
chr25_-_19224298 0.26 ENSDART00000149917
acanb
aggrecan b
chr5_-_6567464 0.26 ENSDART00000184985
tnks1bp1
tankyrase 1 binding protein 1
chr25_+_4760489 0.25 ENSDART00000167399
FP245455.1

chr4_-_4834617 0.25 ENSDART00000141539
coa6
cytochrome c oxidase assembly factor 6
chr24_+_35881124 0.25 ENSDART00000143015
klhl14
kelch-like family member 14
chr17_+_8212477 0.25 ENSDART00000064665
slc18b1
solute carrier family 18, subfamily B, member 1
chr20_-_34750045 0.25 ENSDART00000186130
znf395b
zinc finger protein 395b
chr1_-_15797663 0.25 ENSDART00000177122
SGCZ
sarcoglycan zeta
chr19_+_233143 0.24 ENSDART00000175273
syngap1a
synaptic Ras GTPase activating protein 1a
chr5_+_37903790 0.24 ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr17_-_36896560 0.24 ENSDART00000045287
mapre3a
microtubule-associated protein, RP/EB family, member 3a
chr14_-_858985 0.24 ENSDART00000148687
ENSDART00000149375
slc34a1a
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1a
chr19_-_12648122 0.24 ENSDART00000151184
fam210aa
family with sequence similarity 210, member Aa
chr3_-_56541723 0.23 ENSDART00000156398
ENSDART00000050576
ENSDART00000184874
si:ch211-189a21.1
cyth1a
si:ch211-189a21.1
cytohesin 1a
chr2_+_44571200 0.23 ENSDART00000098132
klhl24a
kelch-like family member 24a
chr25_-_19648154 0.23 ENSDART00000148570
atp2b1b
ATPase plasma membrane Ca2+ transporting 1b
chr25_-_29087925 0.23 ENSDART00000171758
rpp25a
ribonuclease P and MRP subunit p25, a
chr4_+_74929427 0.23 ENSDART00000174082
nup50
nucleoporin 50
chr22_-_10121880 0.22 ENSDART00000002348
rdh5
retinol dehydrogenase 5 (11-cis/9-cis)
chr11_+_28476298 0.22 ENSDART00000122319
lrrc38b
leucine rich repeat containing 38b
chr3_+_17537352 0.22 ENSDART00000104549
hcrt
hypocretin (orexin) neuropeptide precursor
chr11_-_39044595 0.22 ENSDART00000065461
cldn19
claudin 19
chr9_+_50001746 0.22 ENSDART00000058892
slc38a11
solute carrier family 38, member 11
chr15_-_33925851 0.22 ENSDART00000187807
ENSDART00000187780
mag
myelin associated glycoprotein
chr23_+_28582865 0.22 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr4_+_3980247 0.21 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr25_-_13842618 0.21 ENSDART00000160258
mapk8ip1a
mitogen-activated protein kinase 8 interacting protein 1a
chr10_-_35103208 0.21 ENSDART00000192734
zgc:110006
zgc:110006
chr1_-_19845378 0.21 ENSDART00000139314
ENSDART00000132958
ENSDART00000147502
grhprb
glyoxylate reductase/hydroxypyruvate reductase b
chr19_-_12648408 0.21 ENSDART00000103692
fam210aa
family with sequence similarity 210, member Aa
chr24_+_16547035 0.21 ENSDART00000164319
sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr11_+_5588122 0.21 ENSDART00000113281
zgc:172302
zgc:172302
chr5_-_16996482 0.20 ENSDART00000144501
galnt9
polypeptide N-acetylgalactosaminyltransferase 9
chr3_+_45687266 0.20 ENSDART00000131652
gpr146
G protein-coupled receptor 146
chr11_-_40257225 0.20 ENSDART00000139009
TRIM62 (1 of many)
si:ch211-193i15.2
chr7_-_28148310 0.20 ENSDART00000044208
lmo1
LIM domain only 1
chr23_-_42752550 0.20 ENSDART00000187059
si:ch73-217n20.1
si:ch73-217n20.1
chr22_-_21897203 0.20 ENSDART00000158501
ENSDART00000105566
ENSDART00000136795
gna11a
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr4_-_28158335 0.20 ENSDART00000134605
gramd4a
GRAM domain containing 4a
chr20_-_1141722 0.20 ENSDART00000152675
gabrr1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr19_-_9882821 0.20 ENSDART00000147128
cacng7a
calcium channel, voltage-dependent, gamma subunit 7a
chr12_-_46112892 0.20 ENSDART00000187128
ENSDART00000114268
zgc:153932
zgc:153932
chr19_-_5103141 0.19 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr19_-_5103313 0.19 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr3_-_32902138 0.18 ENSDART00000144026
ENSDART00000083874
ENSDART00000145443
ENSDART00000148239
ENSDART00000134917
kat7a
K(lysine) acetyltransferase 7a
chr21_-_32060993 0.18 ENSDART00000131651
si:ch211-160j14.2
si:ch211-160j14.2
chr9_+_17983463 0.18 ENSDART00000182150
akap11
A kinase (PRKA) anchor protein 11
chr18_+_28106139 0.18 ENSDART00000089615
kiaa1549lb
KIAA1549-like b
chr10_+_16584382 0.18 ENSDART00000112039
CR790388.1

chr12_-_33357655 0.18 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr2_-_15324837 0.17 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr12_+_10631266 0.17 ENSDART00000161455
csf3a
colony stimulating factor 3 (granulocyte) a
chr3_+_62353650 0.17 ENSDART00000112428
iqck
IQ motif containing K
chr1_+_23161369 0.17 ENSDART00000162827
si:dkey-92j12.5
si:dkey-92j12.5
chr12_+_16168342 0.17 ENSDART00000079326
ENSDART00000170024
lrp2b
low density lipoprotein receptor-related protein 2b
chr4_-_68563862 0.17 ENSDART00000182970
BX548011.2

chr13_-_29420885 0.17 ENSDART00000024225
chata
choline O-acetyltransferase a
chr8_+_20776654 0.17 ENSDART00000135850
nfic
nuclear factor I/C
chr17_-_37195163 0.17 ENSDART00000108514
asxl2
additional sex combs like transcriptional regulator 2
chr6_-_51386656 0.17 ENSDART00000154732
ENSDART00000177990
ENSDART00000184928
ENSDART00000180197
ptprt
protein tyrosine phosphatase, receptor type, t
chr9_-_23994225 0.17 ENSDART00000140346
col6a3
collagen, type VI, alpha 3
chr14_-_7207961 0.16 ENSDART00000167994
ENSDART00000166532
stox2b
storkhead box 2b
chr17_-_5610514 0.16 ENSDART00000004043
enpp4
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr4_-_4834347 0.16 ENSDART00000141803
coa6
cytochrome c oxidase assembly factor 6
chr8_+_49778756 0.16 ENSDART00000083790
ntrk2a
neurotrophic tyrosine kinase, receptor, type 2a
chr5_-_58112032 0.16 ENSDART00000016418
drd2b
dopamine receptor D2b
chr4_-_17629444 0.16 ENSDART00000108814
nrip2
nuclear receptor interacting protein 2
chr11_-_42554290 0.16 ENSDART00000130573
atp6ap1la
ATPase H+ transporting accessory protein 1 like a
chr6_+_24398907 0.15 ENSDART00000167482
tgfbr3
transforming growth factor, beta receptor III
chr17_-_37195354 0.15 ENSDART00000190963
asxl2
additional sex combs like transcriptional regulator 2
chr6_+_102506 0.15 ENSDART00000172678
ldlrb
low density lipoprotein receptor b
chr23_-_35790235 0.15 ENSDART00000142369
ENSDART00000141141
ENSDART00000011004
mfsd5
major facilitator superfamily domain containing 5
chr25_+_13621563 0.15 ENSDART00000159428
si:ch211-172l8.4
si:ch211-172l8.4
chr8_-_3773374 0.14 ENSDART00000115036
bicdl1
BICD family like cargo adaptor 1
chr5_+_36768674 0.14 ENSDART00000146854
mark4a
MAP/microtubule affinity-regulating kinase 4a
chr13_+_15838151 0.14 ENSDART00000008987
klc1a
kinesin light chain 1a
chr19_+_7152966 0.13 ENSDART00000080348
brd2a
bromodomain containing 2a
chr6_+_24420523 0.13 ENSDART00000185461
tgfbr3
transforming growth factor, beta receptor III
chr10_-_5847655 0.13 ENSDART00000192773
ankrd55
ankyrin repeat domain 55
chr21_+_32820175 0.13 ENSDART00000076903
adra2db
adrenergic, alpha-2D-, receptor b
chr18_-_43884044 0.13 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr12_-_6880694 0.13 ENSDART00000171846
pcdh15b
protocadherin-related 15b
chr4_-_77557279 0.13 ENSDART00000180113
AL935186.10

chr10_+_31222433 0.13 ENSDART00000185080
tmem218
transmembrane protein 218
chr2_-_32558795 0.13 ENSDART00000140026
smarcd3a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3a
chr11_-_2838699 0.12 ENSDART00000066189
lhfpl5a
LHFPL tetraspan subfamily member 5a
chr24_-_39518599 0.12 ENSDART00000145606
ENSDART00000031486
lyrm1
LYR motif containing 1
chr6_+_39232245 0.12 ENSDART00000187351
b4galnt1b
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr23_-_42752387 0.12 ENSDART00000149781
si:ch73-217n20.1
si:ch73-217n20.1
chr15_-_34785594 0.12 ENSDART00000154256
gabbr1a
gamma-aminobutyric acid (GABA) B receptor, 1a
chr19_-_657439 0.12 ENSDART00000167100
slc6a18
solute carrier family 6 (neutral amino acid transporter), member 18
chr11_-_44801968 0.11 ENSDART00000161846
map1lc3c
microtubule-associated protein 1 light chain 3 gamma
chr1_-_513762 0.11 ENSDART00000148162
ENSDART00000144606
trmt10c
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr5_-_64831207 0.11 ENSDART00000144816
lix1
limb and CNS expressed 1
chr17_-_47220934 0.11 ENSDART00000158740
alk
ALK receptor tyrosine kinase
chr2_+_35728033 0.10 ENSDART00000002094
ankrd45
ankyrin repeat domain 45
chr1_-_5455498 0.10 ENSDART00000040368
ENSDART00000114035
mnx2b
motor neuron and pancreas homeobox 2b
chr2_+_20605186 0.10 ENSDART00000128505
olfml2bb
olfactomedin-like 2Bb
chr8_-_21142550 0.10 ENSDART00000143192
ENSDART00000186820
ENSDART00000135938
cpt2
carnitine palmitoyltransferase 2
chr1_-_44701313 0.10 ENSDART00000193926
si:dkey-28b4.8
si:dkey-28b4.8
chr12_-_46145635 0.10 ENSDART00000074682
zgc:153932
zgc:153932
chr1_+_18811679 0.10 ENSDART00000078610
slc25a51a
solute carrier family 25, member 51a
chr5_+_19094153 0.10 ENSDART00000186525
ENSDART00000064752
unc13ba
unc-13 homolog Ba (C. elegans)
chr15_-_14552101 0.10 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr9_-_9415000 0.10 ENSDART00000146210
si:ch211-214p13.9
si:ch211-214p13.9
chr6_-_6487876 0.10 ENSDART00000137642
cep170ab
centrosomal protein 170Ab
chr4_-_68868700 0.10 ENSDART00000187985
si:dkey-264f17.5
si:dkey-264f17.5
chr3_-_29941357 0.10 ENSDART00000147732
ENSDART00000137973
ENSDART00000103523
grna
granulin a
chr10_-_32494304 0.10 ENSDART00000028161
uvrag
UV radiation resistance associated gene
chr10_-_11261565 0.10 ENSDART00000146727
ptbp3
polypyrimidine tract binding protein 3
chr14_+_14662116 0.09 ENSDART00000161693
cetn2
centrin, EF-hand protein, 2
chr25_-_10791437 0.09 ENSDART00000127054
BX572619.1

chr17_+_50524573 0.09 ENSDART00000187974
CR382385.1

chr8_+_49778486 0.09 ENSDART00000131732
ntrk2a
neurotrophic tyrosine kinase, receptor, type 2a
chr10_+_42423318 0.09 ENSDART00000134282
npy8ar
neuropeptide Y receptor Y8a
chr17_+_11675362 0.09 ENSDART00000157911
kif26ba
kinesin family member 26Ba
chr16_-_26296477 0.09 ENSDART00000157553
erfl1
Ets2 repressor factor like 1
chrM_+_8130 0.09 ENSDART00000093609
mt-co2
cytochrome c oxidase II, mitochondrial
chr10_-_5581487 0.09 ENSDART00000141943
syk
spleen tyrosine kinase
chr13_+_2442841 0.09 ENSDART00000114456
ENSDART00000137124
ENSDART00000193737
ENSDART00000189722
ENSDART00000187485
arfgef3
ARFGEF family member 3
chr18_-_48547564 0.09 ENSDART00000138607
kcnj1a.1
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr11_+_41540862 0.08 ENSDART00000173210
kcnab2a
potassium voltage-gated channel, shaker-related subfamily, beta member 2 a

Network of associatons between targets according to the STRING database.

First level regulatory network of lhx6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.9 GO:0061075 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.1 0.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.4 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.4 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.1 0.3 GO:1990416 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.8 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 0.3 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.1 0.3 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.2 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.1 0.2 GO:0042755 eating behavior(GO:0042755)
0.1 0.3 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.2 GO:0034164 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.2 GO:0070316 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.4 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.4 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.3 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.7 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 0.1 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.2 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.1 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.3 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.2 GO:0050820 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.0 0.2 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:2000434 regulation of protein neddylation(GO:2000434)
0.0 0.6 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.1 GO:0090330 regulation of platelet activation(GO:0010543) positive regulation of cell adhesion mediated by integrin(GO:0033630) regulation of platelet aggregation(GO:0090330)
0.0 1.1 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.4 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.2 GO:0033700 phospholipid efflux(GO:0033700)
0.0 0.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.3 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.3 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 0.1 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.4 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.1 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.3 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.0 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.0 0.3 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0035493 SNARE complex assembly(GO:0035493)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0030891 VCB complex(GO:0030891)
0.1 0.5 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.4 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.1 GO:0030677 ribonuclease P complex(GO:0030677)
0.0 0.8 GO:0043204 perikaryon(GO:0043204)
0.0 0.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.7 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.3 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.1 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0005903 brush border(GO:0005903)
0.0 0.0 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.0 0.1 GO:0032420 stereocilium(GO:0032420)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.3 GO:0060175 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 0.2 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.6 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 1.0 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.4 GO:0042936 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.3 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0090554 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.3 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.6 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.0 GO:0031530 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.0 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.1 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.0 0.1 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions